F-Prime Capital Partners
Boston · Pre-Seed–Late Stage · 99 people tracked
Investment thesis
F-Prime believes that successful investing requires venture investors to embody the same entrepreneurial drive as the founders they back. The firm targets transformative breakthroughs across healthcare—including therapeutics, medical devices, and health services—and technology including enterprise software, frontier technologies, and cryptocurrency. Though primarily an early-stage investor by philosophy, the firm maintains flexibility to support exceptional teams across all funding stages. The firm's deep bench of domain experts enables hands-on support for portfolio companies pursuing scalable growth.
Source: firm website, verified Jul 20, 2026.
Team · 99 people
from the firm's websiteWhat they invest in
from 20 of 383 portfolio companiesBiotech ×8Healthtech ×8Medical Devices ×8AI & Machine Learning ×7Deep Tech ×4Enterprise Software ×4SaaS ×4Digital Health ×3
HQs:United States×12United Kingdom×1
Investments · showing 60 of 383
founders shown can be your intro path1Money builds a decentralized payment network for stablecoin and tokenized deposit transfers, designed for global financial settlements. The network emphasizes security, compliance, and transaction speed without smart contract vulnerabilities.
Crypto & Web3Fintech
Aclaris develops investigational monoclonal antibodies and small-molecule inhibitors targeting immune pathways for the treatment of atopic, autoimmune, and respiratory diseases. The company's clinical and preclinical pipeline includes candidates in development for severe asthma, atopic dermatitis, and T-cell-mediated autoimmune conditions.
BiotechHealthtechMedical Devices
Adagene is a clinical-stage immunotherapy company that uses computational biology and artificial intelligence to discover and design therapeutic antibodies for cancer treatment. The company's platform generates novel antibodies aimed at improving safety and efficacy in precision-guided antibody-drug conjugates and other therapeutic approaches.
AI & Machine LearningBiotech
Adaptimmune Therapeutics is a biotechnology company, though the specific focus of their therapeutic work is not detailed on this investors and media page.
BiotechHealthtechMedical Devices
Aera Therapeutics develops genetic medicines using next-generation delivery technologies and precision payloads optimized for specific diseases. The company focuses on advancing transformative treatments in areas including oncology, rare genetic diseases, and cell therapies.
AI & Machine LearningBiotechDeep TechMedical Devices
Akin Akinc, Ph.D.(CEO)
Affinia Therapeutics develops genetically engineered adeno-associated virus (AAV) therapies for treating genetic diseases, focusing initially on cardiovascular and central nervous system conditions. The company uses AI and structural modeling to redesign viral delivery vectors for one-time-dose genetic medicines across rare and prevalent diseases.
AI & Machine LearningBiotechDeep Tech
Albert provides an operating system for chemists that combines structured data management with AI trained on molecular structures and individual company chemistry datasets. The platform centralizes lab notebooks, experiments, and projects while enabling AI-driven predictions for formulation optimization and discovery acceleration in materials and chemical R&D.
AI & Machine LearningDeep TechEnterprise Software
Alfred Pay provides an API and platform enabling businesses to issue local bank accounts and move money across Latin American countries without establishing local entities. It serves crypto platforms, fintech companies, and trade/logistics businesses needing local currency payments and instant settlements.
FintechSaaS
Alibaba.com operates a global B2B e-commerce marketplace that connects buyers with suppliers and manufacturers for wholesale products across multiple industries. The platform provides trade services, logistics support, payment protection, and AI-powered sourcing tools for businesses.
AI & Machine LearningB2B MarketplacesE-commerce
Amber Therapeutics develops medical technology focused on treating mixed urinary incontinence, advancing toward pivotal clinical trials in the US with expanded feasibility studies in Europe.
Medical Devices
AmplifyMD provides an EHR-integrated virtual care platform combined with a network of remote specialists to help hospitals and health systems expand telehealth services, automate clinical workflows, and manage virtual care programs. The platform serves healthcare organizations seeking to deliver remote consultations and specialist coverage across their operations.
Digital HealthEnterprise SoftwareHealthtech
AppliedVR develops immersive therapeutic software using technology to deliver drug-free clinical treatments for patients. The company focuses on healthcare applications where traditional medical approaches have limitations.
Digital HealthHealthtechMedical DevicesLos Angeles, US
Matthew Stoudt(Co-Founder and CEO)Josh Sackman(Co-Founder and President)David Sackman(Chairman)
Beam Therapeutics develops gene-editing medicines, particularly base editors and precision genome editing technologies, to create lifelong cures for patients with serious genetic diseases. The company works across multiple therapeutic areas to advance precision medicine treatments at the molecular level.
BiotechDeep TechMedical DevicesCambridge, US
John Evans(CEO)David R. Liu(Founder and Inventor)J. Keith Joung(Founder and Inventor)Feng Zhang(Founder and Inventor)
Benchling provides an AI-powered cloud platform for scientific research teams to design experiments, automate lab workflows, and manage structured data from biomolecules to cell lines. The platform integrates predictive models, lab automation, and data capture to help researchers in biotech and life sciences accelerate discovery cycles.
AI & Machine LearningBiotechEnterprise SoftwareSaaSSan Francisco, US
Sajith Wickramasekara(Founder/CEO)
Board seats · per SEC filings · 4
what is this? ⓘ$20M raise · filed Jun 2026 · via Martin Garcia Taylor, Nihal Garcia Sinha
$75M raise · filed Jan 2024 · via Ketan Scott Patel, Muzammil Scott Mansuri
$45M raise · filed Apr 2023 · via David Scott Jegen
$20M raise · filed Apr 2023 · via Muzammil Singh Mansuri, Nihal Singh Sinha
Inferred from directors named on each company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Frequently asked questions
- What stage does F-Prime Capital Partners invest at?
- F-Prime Capital Partners invests at the Pre-Seed, Seed, Series A, Series B, Series C, Growth, Late Stage stages.
- What sectors does F-Prime Capital Partners focus on?
- F-Prime Capital Partners focuses on Biotech, Crypto & Web3, Deep Tech, Enterprise Software, Fintech, Healthtech, Medical Devices.
- Where is F-Prime Capital Partners located?
- F-Prime Capital Partners is headquartered in Boston, US.
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