F-Prime Capital Partners
Venture capitalCambridge · Pre-Seed–Late Stage · 104 people tracked
Also known as IMPRESA MANAGEMENT LLC
Investment thesis
F-Prime helps founders turn bold ambitions into breakthroughs across life sciences, technology, healthtech + services, and crypto. In healthcare, the firm invests in therapeutics, medtech, and healthtech + services in a stage-agnostic manner. In technology, it focuses on enterprise software, fintech, frontier tech, and crypto. Although it prefers early-stage investing, it will support exceptional teams at any stage. Its team includes scientists, engineers, physicians, operators, and investors who bring real-world expertise to help companies accelerate toward scalable growth.
Source: firm website, verified Aug 3, 2026.
Team · 104 people
from the firm's website & public directoriesWhat they invest in
from 155 of 393 portfolio companiesBiotech ×64Healthtech ×62Medical Devices ×40AI & Machine Learning ×31Digital Health ×30Enterprise Software ×30Fintech ×26SaaS ×25
HQs:United States×113China×3India×3United Kingdom×2Japan×2Brazil×1
Investments · 393 tracked
founders shown can be your intro pathCaribou Biosciences is a clinical-stage biopharmaceutical company developing CRISPR genome-editing therapies, including off-the-shelf CAR-T cell therapies for hematologic malignancies and armored cell therapies using its Cas12a chRDNA platform.
BiotechMedical DevicesBerkeley, US
Jennifer Doudna(Co-founder)Rachel Haurwitz(President and Chief Executive Officer, Co-founder)Martin Jinek(Co-founder)Andrew May(Executive Officer)Rodolphe Barrangou(Director)Jenny Rooke(Director)
Board seatRobert Weisskoff· per SEC Form D
Neumora is a clinical research company developing investigational medications, with a focus on conducting clinical trials to obtain regulatory approval and make treatments available to patients.
BiotechDeep TechDigital HealthMedical DevicesWatertown, US
Kristina Burow(Director)Matthew Fust(Director)Robert Nelsen(Director)Kari Stefansson(Director)Paul Berns(Executive Officer, Director)Stacie Weninger(Director)
Board seatStacie Weninger· per SEC Form D
Boston, US
John Raguin(Director)Phillip Riese(Director)Matthew Harris(Director)Alex Finkelstein(Director)Pablo Ventura Aranguren(Director)Michael Massaro(Executive Officer, Director)
Board seatDavid Jegen· per SEC Form D · $171.1M raise · filed Feb 2020
BiotechSouth San Francisco, US
Robert Weisskoff(Director)Ramy Farid(Director)Jessica Lifton(Director)Ting Xie(Director)Raymond Stevens(Director)Daniel Auerbach(Director)
Board seatRobert Weisskoff· per SEC Form D · $7M raise · filed Jan 2022
BiotechBrisbane, US
Stephen Brady(Director)Christine Pellizzari(Director)Matthew Angel(Executive Officer, Director)Ronit Simantov(Director)Michael Raab(Director)Nicholas Maestas(Executive Officer)
Board seatRobert Weisskoff· per SEC Form D
BiotechWaltham, US
Paul Clancy(Director)Daniel Curran(Director)Peter Dudek(Director)David Grayzel(Director)Nancy Hong(Director)Rachel Humphrey(Director)
Board seatRobert Weisskoff· per SEC Form D · $50.2M raise · filed Jan 2021
Aclaris develops investigational monoclonal antibodies and small-molecule inhibitors targeting immune pathways for the treatment of atopic, autoimmune, and respiratory diseases.
BiotechHealthtechMedical DevicesWayne, US
Neal Walker(Executive Officer, Director)Joseph Monahan(Executive Officer)Hugh Davis(Executive Officer, Director)James Loerop(Executive Officer)Kevin Balthaser(Executive Officer)Kamil Ali-Jackson(Executive Officer)
Adagene is a clinical-stage immunotherapy company that uses computational biology and artificial intelligence to discover and design therapeutic antibodies for cancer treatment.
AI & Machine LearningBiotech
Avalyn Pharma develops a nebulized inhalation treatment for pulmonary fibrosis designed to improve tolerability compared to existing oral therapies by directly delivering the drug to the lungs.
BiotechMedical Devices
Lyn Baranowski(CEO)in
Beam Therapeutics develops gene-editing medicines, particularly base editors and precision genome editing technologies, to create lifelong cures for patients with serious genetic diseases.
BiotechDeep TechMedical DevicesCambridge, US
David R. Liu(Founder and Inventor)J. Keith Joung(Founder and Inventor)Feng Zhang(Founder and Inventor)CAROLE HO(Director)John Evans(Executive Officer, Director)MARK FISHMAN(Director)
Coherus Oncology develops and commercializes immuno-oncology therapies, including the approved LOQTORZI, to treat patients with cancer.
BiotechHealthtechMedical DevicesRedwood City, US
Barbara K Finck, M.D.(Executive Officer)Ali J. Satvat(Director)Mats Wahlstrom(Director)Alan C. Herman(Executive Officer)Dennis M. Lanfear(Executive Officer, Director)Jean-Frederic Viret, Ph.D.(Executive Officer)
Coinbase is a cryptocurrency exchange platform that offers trading, custody, and financial services for cryptocurrencies, stocks, derivatives, and prediction markets to consumers, institutions, and developers.
Crypto & Web3FintechLos Angeles, US
Brian Armstrong(Founder/CEO)in
Cambridge, US
Cytek Biosciences develops high-parametric analytical instruments and software that enable scientists at pharmaceutical companies, contract research organizations, and academic institutions to generate and analyze biological datasets.
BiotechDeep TechHardwareHealthtechMedical DevicesBellevue, US
Wenbin Jiang, Ph.D.(CEO and Chairman of the Board)Ming Yan, Ph.D.(Chief Technology Officer)Ming Yan(Executive Officer, Director)Jiecheng Zhang(Director)Allen Poirson(Director)Andrew Levin(Director)
Denali Therapeutics develops therapeutics for neurodegenerative diseases.
BiotechHealthtechMedical DevicesSan Francisco, US
Carole Ho(Executive Officer)Vicki L. Sato(Director)Nancy A. Thornberry(Director)Peter S. Klein(Director)Marc Tessier-Lavigne(Director)Jay T. Flatley(Director)
Insmed is a biopharmaceutical company that provides grants and charitable funding to support healthcare provider education and patient care initiatives focused on nontuberculous mycobacterial lung disease, non-cystic fibrosis bronchiectasis, and other serious lung diseases.
BiotechDigital HealthHealthtechMedical Devices<UNKNOWN>, US
Precision BioSciences is a clinical-stage biotechnology company developing genome-editing therapies based on its ARCUS platform.
BiotechDeep TechHealthtechDurham, US
JEFF SMITH(Executive Officer)DEREK JANTZ(Executive Officer, Director)MATTHEW KANE(Executive Officer, Director)TODD MELBY(Executive Officer)BEN AUSPITZ(Director)Jeff Smith(Co-founder)
Prime Medicine develops Prime Editing, a gene editing platform designed to correct disease-causing mutations in the human genome.
BiotechHealthtechMedical Devices
Seattle, US
Boston, US
Stephen Fredette(Executive Officer, Director, Promoter)Steve Papa(Director, Promoter)Jonathan Grimm(Director, Promoter)Christopher Comparato(Executive Officer, Director)Aman Narang(Director, Promoter)
PartnerDavid Jegen· led
Cogent Biosciences discovers, develops, and commercializes therapies targeting genetically defined diseases, with a focus on precision medicine and addressing underlying causes rather than symptoms.
BiotechDigital HealthMedical DevicesCambridge, US
Ben Auspitz(Director)Liam Ratcliffe(Director)Charles Wilson(Executive Officer, Director)Christiana Stamoulis(Executive Officer)
BoardBruce Booth(Director)
1up.Health provides healthcare data acquisition, management, and integration solutions for insurance payers.
Data & InfrastructureHealthtechBoston, US
Victor Echevarria(Director)David Jegan(Director)T. Scott Law, Jr.(Director)Joseph Gagnon(Director)Ritwik Sahu(Executive Officer, Director)
Board seatDavid Jegen· per SEC Form D
Affinia Therapeutics develops genetically engineered adeno-associated virus (AAV) therapies for treating genetic diseases, focusing initially on cardiovascular and central nervous system conditions.
AI & Machine LearningBiotechDeep TechWaltham, US
Carole Faig(Director)Rami Daoud(Executive Officer)Diana Brainard(Director)Rick Modi(Executive Officer, Director)Luc Vandenberghe(Director)Elliott Sigal(Director)
Board seatRobert Weisskoff· per SEC Form D
HealthtechMaple Grove, US
Michael Liang(Director)Dan Sachs(Director)Tom Ressemann(Executive Officer, Director)
Board seatRobert Weisskoff· per SEC Form D
BiotechEncinitas, US
Ankit Mahadevia(Executive Officer, Director)Ben Auspitz(Director)Martin Taylor(Director)Carlos Garcia Echeverria(Director)Nihal Sinha(Director)Brian Laurence Johnson(Executive Officer, Director)
Board seatMartin TaylorNihal Sinha· per SEC Form D · $20M raise · filed Jun 2026
Buoy provides digital health symptom assessment and decision support to help people navigate healthcare more effectively.
Digital HealthHealthtechBoston, US
Adam Lathram(Executive Officer, Director, Promoter)Jose Eduardo Reyes(Director)Andrew Le(Executive Officer, Director, Promoter)Nathanael Yu Ren(Director)
Board seatCarl Byers· per SEC Form D
HealthtechLondon
Gary Glick(Director)Rishi Gupta(Director)Nihal Sinha(Director)Lakshyaditya Singh Aithani(Executive Officer, Director)Muzammil Mansuri(Director)
Board seatMuzammil MansuriNihal Sinha· per SEC Form D · $20M raise · filed Apr 2023
BiotechCambridge, US
Barry Labinger(Executive Officer, Director)Ben Auspitz(Director)Art Krieg(Executive Officer, Director)Chuck Abdalian(Executive Officer)David Mauro(Executive Officer)Karen Brennan(Executive Officer)
Board seatRobert Weisskoff· per SEC Form D
BiotechConcord, US
Arthur Levin(Director)Brendan Bulik-Sullivan(Director)Muzammil Mansuri(Director)Paul Antinori(Executive Officer)Allison August(Executive Officer)Ann Taylor(Director)
Board seatKetan PatelMuzammil Mansuri· per SEC Form D
Boston, US
Board seatCarl Byers· per SEC Form D · $75M raise · filed Jul 2021
Boston, US
Board seatStephen Knight· per SEC Form D · $79M raise · filed Jan 2023
BiotechCambridge, US
Geoff McDonoughy(Executive Officer, Director)Glenn Goddard(Executive Officer)Jason Rhodes(Director)Anthony Quinn(Director)Gustav Christensen(Director)Donald Nicholson(Director)
Board seatCatherine Stehman-Breen· per SEC Form D · $100.4M raise · filed Mar 2018
Notabene provides compliance and regulatory technology for crypto businesses and financial institutions, helping them meet regulatory requirements like the FATF Crypto Travel Rule through real-time screening, sanctions checks, and wallet identification.
Crypto & Web3CybersecurityEnterprise SoftwareFintechNew York City, US
Pelle Braendgaard(CEO/ Co-Founder)inAndres Junge(Founder)inAnia Lipinska(Founder)inAlice Nawfal(Founder)inMatthew Walsh(Director)Peter Johnson(Director)
Board seatDavid Jegen· per SEC Form D
Miami, US
Chris Downer(Director)Rafi Lurie(Director)Robert Nance(Executive Officer, Director, Promoter)Madalyn Armijo(Director, Promoter)
Board seatDavid Jegen· per SEC Form D · $18M raise · filed Jul 2025
Walnut, US
Roberto Cebrian Flores(Executive Officer, Director)David Villarreal Ortiz(Executive Officer, Director)
Board seatDavid Jegen· per SEC Form D · $5M raise · filed Feb 2024
Seattle, US
Robert Shepler(Director)Ronald Seubert(Executive Officer, Director, Promoter)Evan Castiglia(Executive Officer)Brian Daniels(Director)Joseph Victor(Executive Officer, Director)Frank Witney(Director)
Board seatRobert Weisskoff· per SEC Form D
San Francisco, US
John Martinez(Director)Edgar Green(Director)Thomas Sponholtz(Executive Officer, Director)James Riccitelli(Executive Officer, Director)Douglas H. Lowrey(Director)
Board seatDavid Jegen· per SEC Form D · $40M raise · filed Jun 2018
Snapdocs automates the digital mortgage closing process by connecting lending, settlement, and secondary market teams.
AI & Machine LearningFintechLegalTechPropTechSaaSPortland, US
Aaron King(Founder/CEO)inMatt Schindel(Executive Officer)Anu Hariharan(Director)Ian Small(Director)Sanam Pangali(Executive Officer)
Board seatDavid Jegen· per SEC Form D · $150M raise · filed May 2021
CybersecurityBoston, US
Brian Ahern(Executive Officer, Director)
Board seatGaurav Tuli· per SEC Form D
Charlotte, US
Dan Raju(Executive Officer, Director)Robert Kopple(Director)
Board seatDavid Jegen· per SEC Form D
Brooklyn, US
Jacey Jones(Executive Officer, Director, Promoter)Christopher John Graves(Executive Officer, Director, Promoter)
Board seatGaurav Tuli· per SEC Form D
Oakwood Village, US
David Chandler(Mr. Chandler is the Chief Financial Officer of the Issuer.)Joshua Bilenker(Director)Mark Roemer(Director)David Bonita(Director)Robert Weisskoff(Director)Philip Yang(Director)
Board seatRobert Weisskoff· per SEC Form D
Zenflow develops medical devices for treating benign prostatic hyperplasia (BPH) in men, founded from the Stanford Byers Center for Biodesign with a team experienced in medical device development and FDA regulation.
HealthtechMedical DevicesSan Francisco, US
Shreya Mehta(Founder/CTO)inJohn Beck(Executive Officer)Nick Damiano(Executive Officer, Director)
BoardBryan Kim(Director)Blayne Roeder(Director)
Board seatRobert Weisskoff· per SEC Form D · $25.2M raise · filed Nov 2024
Zus provides a platform that removes data waste in healthcare, enabling developers, clinicians, and operators to innovate in patient and care team experience without building underlying infrastructure.
Cloud ComputingData & InfrastructureDigital HealthHealthtechWatertown, US
Jonathan Bush(CEO)inSteven Fisher(Director)Fay Rotenberg(Director)Benjamin Silver(Director)Travis Smith(Executive Officer)
BoardJulie Yoo(Director)
Board seatCarl Byers· per SEC Form D · $40M raise · filed Mar 2023
Biotech
James A. Geraghty(Director)Joanne T. Beck(Director)Bobby Gaspar(Executive Officer, Director)Marc Dunoyer(Director)Steven M. Altschuler(Director)Frank E. Thomas(Executive Officer)
ABK Biomedical is a clinical-stage medical device company developing imageable microsphere products for treating cancer, including Eye90 microspheres for Y90 radioembolization in liver cancer and Easi-Vue embolic microspheres for embolization of arteriovenous malformations and hypervascular tumors.
BiotechHealthtechMedical DevicesHalifax, CA
Anthony Headley(Executive Officer)Gary Donofrio(Executive Officer)Michael Mangano(Executive Officer, Director)David Dobrowsky(Executive Officer)Keten Patel(Director)Lucy Bataneant(Executive Officer)
Adaptimmune Therapeutics is a biotechnology company, though the specific focus of their therapeutic work is not detailed on this investors and media page.
BiotechHealthtechMedical Devices
Adcentrx Therapeutics is a clinical-stage biotechnology company developing protein conjugate therapeutics for cancer and other life-threatening diseases.
BiotechHealthtech
Browse all 393 investments with full details →
▶193 more tracked companies
Iriva MedicalIRWDIvenixJumpK36 TherapeuticsKanastraKenshoKilnKintsuKnowyourselfKryuus IncLakeShore BiopharmaLatchelLaurus BioLaurus LabsLeadiqLemonLenomedLeyden LabsLiazonLighthouseLigocyteLimitless ExchangeLogixboardMadaketMarit HealthMddfMedbanksMeditrust HealthMedwellMeldMetcelaMetseraMindshiftMineralTreeModis TherapeuticsMoEngageMonark MarketsMyolabMythical GamesNanos MedicalNapsterNava TherapeuticsnChroma BioNebula GenomicsNeo4jNeurosmartNextwavepharmaNflection TherapeuticsnocdNocion TherapeuticsNodtheraNotableNovamed PharmaceuticalsNuance CommunicationsNYDIGOakley NetworksOdasevaOncoveryCareOncusp TherapeuticsOpennodeOptimus RideOrient Speech Therapy OstOrigynmedOviva PRIVATE DEBTOWKINOwncloud IncOxioOzivaPapaya PaymentsParadigmParrotPathPatientPingPediatrix TherapeuticsPeptonePercyPharmEasyPiePing IdentityPlasmagen BiosciencesPlume NetworkPortfolio Category AiPortfolio Category CryptoPortfolio Category EnterprisePortfolio Category FintechPortfolio Category FrontierPortfolio Category MedtechPortfolio Category TherapeuticsPortfolio Region AsiaPortfolio Region EuropePortfolio Region South AmericaPortfolio Status AcquiredPortfolio Status PrivatePortfolio Status PublicProcured HealthPromentis PharmaceuticalsProsperProtenusProteostasis TherapeuticsProximiePuffer FinancePulmocideQuantum CircuitsQuarry TheraQuartet HealthQuovoR1 TherapeuticsReadmeReceipts Depositary CorporationRecurlyRedpineRegenx BiosciencesRespivertRhyGazeRialticRighthand RoboticsRigimmuneRipplRisklensRiskreconRoarkRugen TherapeuticsSecuronixSemma TherapeuticsSeyondShift BioscienceShinobi TherapeuticsSilexonSilqSimonSingular GenomicsSironaxSnapsheetSolidus LabsSolv ProtocolSonderMindSpace and TimeSpectrumaiSpinwheelSpryStride HealthSts DigitalSurface OncologySymbiomixT TherapeuticsTandemaiTct Medical IncTeam Sector CryptoTeam Sector Life SciencesTeam Sector TechnologyTeleoTenpoint TherapeuticsTenvieTetraphase PharmaceuticalsThe Giving BlockTokensoftTokuTopaz PharmaceuticalsTracelinkTradeblockTransaveTreeentTrivitron HealthcareTruth SystemsTurnstone BiologicsU S HealthVestUltragenyxUnbox RoboticsUnbxdValor HealthValrVendrVeridVerve TherapeuticsVestwellVicept Therapeuticsvisit www.mersana.comVitalwareVyne TherapeuticsWanhu HealthcareWarmlyWelbe Healthwell beamWellframeWhatfixWintermuteWww Akrevia ComXaira TherapeuticsXoomZeen HealthZusジェイファーマ株式会社
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Frequently asked questions
- What stage does F-Prime Capital Partners invest at?
- F-Prime Capital Partners invests at the Pre-Seed, Seed, Series A, Series B, Series C, Growth, Late Stage stages.
- What is F-Prime Capital Partners's typical check size?
- F-Prime Capital Partners typically writes checks of $3M – $10M.
- What sectors does F-Prime Capital Partners focus on?
- F-Prime Capital Partners focuses on Biotech, Crypto & Web3, Deep Tech, Digital Health, Enterprise Software, Fintech, Healthtech, Medical Devices, SaaS.
- Where is F-Prime Capital Partners located?
- F-Prime Capital Partners is headquartered in Cambridge, US.
- Does F-Prime Capital Partners lead rounds?
- Yes, F-Prime Capital Partners leads investment rounds.
Images
Co-investors · 165
GV (formerly Google Ventures) is a venture investment firm that backs founders across many industries, aiming to build long-term relationships and support companies across multiple stages and milestones.
Eight Roads Ventures is a venture capital firm that backs and partners with technology and healthcare companies.
ARCH Venture Partners is a venture capital firm that backs and helps build transformational companies, with a strong focus on the life sciences and biotech sector.
Foresite Capital is a multi-stage investment firm focused on healthcare and life sciences, backing companies across all stages of growth. It applies a data science-driven approach to invest in businesses leveraging biology and big data to transform healthcare.
OrbiMed is a global healthcare-focused investment firm providing financing and operational support to companies across biopharmaceuticals, medical devices, digital health, diagnostics, and healthcare services.
Andreessen Horowitz's Strategic Partnerships page describes collaborations that connect its portfolio companies with established institutions to help scale and deploy their technology.
Bessemer Venture Partners is a venture capital firm that partners with entrepreneurs from early stages through every stage of growth, publishing investment roadmaps across multiple technology sectors.
Sofinnova is an investment firm that partners with biotech companies from inception through growth, supporting drug development, the regulatory process, company building, and IPO.
Atlas Venture is a life sciences venture capital firm with three decades of experience investing in and building biotech and medical innovation companies, including startups launched from its own incubator.
RA Capital invests in public and private healthcare and life science companies developing pharmaceuticals, medical devices, and diagnostic tools. The firm operates as a crossover fund across multiple investment stages.
.406 Ventures is an early-stage venture capital firm that partners with founders building companies in healthcare, data and AI, and cybersecurity.
B Capital Group is a global venture capital firm that backs founders from early to late stage, with dedicated stage-based funds and a portfolio spanning technology, healthcare, and energy and resilience sectors.
▶153 more co-investors
Digital Currency Group5AM VenturesOak HC/FTVivo CapitalSpark CapitalCanaan PartnersQED InvestorsSanofi VenturesVolition CapitalSequoia CapitalGeneral CatalystInsight PartnersMenlo VenturesNextView VenturesPolaris PartnersSocial LeverageJAZZ Venture PartnersSofinnova PartnersDigitalis VenturesBrewer Lane VenturesNextech InvestAdvent Life SciencesLightstone VenturesAccelKhosla VenturesGreylock PartnersIndex VenturesBain Capital VenturesTiger Global ManagementInovia CapitalVenrockWinklevoss CapitalFika9Yards CapitalOptum VenturesAnterra CapitalAIFRed Tree VentureFounders FundCraft VenturesNew Enterprise Associates (NEA)Alumni VenturesRedpoint VenturesFounder CollectiveFirst Round CapitalCRV (Charles River Ventures)Plug and Play VenturesEniac VenturesFundersClubFreestyle CapitalLux CapitalSignalFireScale Venture PartnersCanvas VenturesSoftBank Vision FundMaveronLerer HippeauUS Venture PartnersCreandumCiti VenturesFounders' Co-opAccelerator VenturesJackson Square VenturesDawn Capital LLPGolden VenturesKickstart FundXfundMassMutual VenturesJump CapitalVersant VenturesMaven VenturesCambridge Innovation CapitalSparkLabs Global VenturesFlagship Pioneering7wire VenturesArboretum VenturesGPO FundOmega FundsQuesta CapitalaMoonCVS Health VenturesFlyover CapitalHelios Digital VenturesAlkemi Growth CapitalBenchmarkKleiner PerkinsFoundation CapitalGreat Oaks Venture CapitalStreamlined VenturesRRE VenturesUpHonest CapitalForerunner VenturesHeadlineIA VenturesPear VCUpfront VenturesTwo Sigma VenturesThreshold VenturesWingGeneral PartnershipDell Technologies CapitalBetter Tomorrow VenturesSaga VenturesBrainchild HoldingsTCVCompany CapitalHeartcore CapitalFlourish VenturesWork-BenchAmerican Express Ventures (Amex)Mucker CapitalNyca PartnersFf Venture CapitalBDC Venture CapitalHighbury HoldingsRubicon Venture CapitalPitangoIrishAngelsForum VenturesEQT Life SciencesStripeArriveBread And Butter Ventures, LlcForbionPage One VenturesThird Rock VenturesAbingworthPivotal bioVenture PartnersVenture Guides Management, L.P.Firefly HealthPicture CapitalZelkova VenturesArthur VenturesBaird CapitalIn-Q-TelTown Hall VenturesIlluminate FinancialSurface VenturesBrighton Park CapitalHealthQuest CapitalDFJRiverVest VentureFireblocks4BIO CapitalVendep CapitalCasdin CapitalJMI EquityBluebird VenturesDe Novo VenturesNeon AdventuresNina CapitalInternational Finance CorporationWillowWorks
Firms observed investing alongside F-Prime Capital Partners, from public investor directories. Shared companies are the overlap with F-Prime Capital Partners's recorded portfolio.
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