F-Prime Capital — 2024 Investments

Comanche Biopharma is a biopharmaceutical company developing an investigational siRNA medicine (CBP-4888) targeting a root cause of preterm preeclampsia in pregnant women.

BiotechFemTechHealthtechConcord, US

MYMike Young(Founder)inTST Scott Johnson(Founder)inPAPaul Antinori(Executive Officer)AAAllison August(Executive Officer)inThomas Scott Johnson(Executive Officer, Director)

BoardBBBrendan Bulik-Sullivan(Director)in

Board seatMMMuz MansuriKPKetan Patel· per SEC Form D

Co-investorsATAtlas VentureGVGV (Google Ventures)BRBroadview VenturesLILilly Asia VenturesNENew Enterprise Associates (NEA)

TripSuite is a software platform for travel agencies that combines CRM, commission tracking, accounting, itinerary management, analytics, and workflow automation in one system.

SaaSTravel & HospitalityBrooklyn, US

Jacey Jones(Executive Officer, Director, Promoter)inChristopher John Graves(Executive Officer, Director, Promoter)

Board seatGTGaurav Tuli· per SEC Form D

Zenflow develops medical devices for treating benign prostatic hyperplasia (BPH) in men, founded from the Stanford Byers Center for Biodesign with a team experienced in medical device development and FDA regulation.

HealthtechMedical DevicesSan Francisco, US

SMShreya Mehta(CTO)inNDNick Damiano(CEO)inJohn Beck(Executive Officer)in

BoardBryan Kim(Director)Blayne Roeder(Director)

Board seatRWRobert Weisskoff· per SEC Form D

Co-investorsASAstiaCLCloudStone CapitalDODorm RoomSHShangBay Capital LLCY Y CombinatorAGAgrolimen Ventures+15 more

Amber Therapeutics develops medical technology focused on treating mixed urinary incontinence, advancing toward pivotal clinical trials in the US with expanded feasibility studies in Europe.

Medical Devices

Co-investorsINIntuitive VenturesLILightstone VenturesNENew Enterprise Associates (NEA)OXOxford Science Enterprises

AvenCell Therapeutics develops next-generation cell therapies for hard-to-treat cancers, including solid tumors, combining switchable universal CAR-T technology with a CRISPR/Cas9-based allogeneic platform.

BiotechLongevityMedical Devices

ASAndrew Schiermeier(Chief Executive Officer)in

Co-investorsNONovo HoldingsBLBlackstone Life SciencesEIEight Roads VenturesNYNYBC Ventures

Burro builds autonomous robots for agricultural and outdoor operations that mow, tow, carry, and spray to automate manual labor tasks.

AgTechAI & Machine LearningRobotics

TSTerry Scott(Founder)inCharlie Andersen(Founder)Vibhor Sood(Founder)

Co-investorsASAsimov VenturesCACatalyst InvestorsCICIBUS ENTERPRISE FUND II LPEVEverywhere VenturesFFFf Venture CapitalNENextFab Ventures+6 more

Chaos Labs builds AI-driven intelligence and risk-management infrastructure that converts fragmented data into institutional-grade insights, offering risk simulations, parameter tuning, and oracle technology for crypto protocols and financial institutions.

AI & Machine LearningCrypto & Web3Data & Infrastructure

OGOmer Goldberg(Founder)in

Co-investorsBABalaji SrinivasanBLBlueYard CapitalCOCoinbase VenturesGAGalaxy VenturesHAHaun VenturesLILightspeed Venture Partners+14 more

Engrail Therapeutics is a clinical-stage pharmaceutical company developing precision-targeted therapeutics for neupropsychiatric and neurodevelopmental disorders.

BiotechDigital HealthMedical DevicesSan Diego, US

Stephen(Co-founder, EVP Research & Development and Chief Development Officer)Paul Cayer(Chief Financial Officer)inVikram(President and Chief Executive Officer)Kimberly(Chief Scientific Officer)Quentin(Chief Technical Officer)

Co-investorsFOForesite CapitalLOLongwood FundNONorwest Venture PartnersPIPivotal Life SciencesRIRiverVest Venture PartnersYSYsios Capital+4 more

Expressable provides speech therapy services using research-based techniques with a focus on family engagement and accessibility.

Digital HealthHealthtechSaaSAustin, US

NBNicholas Barbara(Executive Officer, Director)inLeanne Sherred(President and Chief Clinical Officer)inBenjamin Pincus(Executive Officer)inSpencer Magloff(Executive Officer)inRyan Hinojosa(Executive Officer)Brett Cook(Director)

Co-investorsDIDigitalis VenturesLELerer HippeauNENextView VenturesHAHarbourVest Partners (Canada)

Genomics company building a multi-ancestry biobank and AI-driven analytics for clinical genetic testing and drug discovery.

HealthtechMiami Lakes, US

CDCarlos D. Bustamante(Executive Officer, Director)inArthur Polk(Executive Officer)Alexander Ioannidis(Director)

BoardWAWale Ayeni(Director)inMohit Kaushal(Director)Nicholas Katsanis(Director)

Co-investorsCECEI VenturesCICitta CapitalFOFounder CollectiveFUFunction VenturesHEHelios Digital VenturesLILifeX Ventures+4 more

Laurus Bio, a subsidiary of Laurus Labs, is a biomanufacturing company using precision fermentation and recombinant DNA technology to produce animal-origin-free recombinant proteins, growth factors, and cell-culture media supplements.

BiotechDeep TechFoodTechNew MaterialsBengaluru, IN

Subramani Ramachandrappa(Founder and Non-Executive Director)inRajesh Krishnamurthy(Executive Director & CEO)inKrishna Kalyan(Executive Director & COO)in

BoardDr. Satyanarayana Chava(Chairman)

Co-investorsEIEight Roads Ventures

Metsera was a clinical-stage biotechnology company developing injectable and oral medicines for obesity and metabolic diseases, including next-generation GLP-1 and amylin-based therapies.

BiotechHealthtechMedical DevicesNew York, US

CAClive A. Meanwell(Director)Christopher J. Visioli(Executive Officer)inBrian Hubbard(Executive Officer)inChristopher Whitten Bernard(Executive Officer, Director)Steven Marso(Executive Officer)Clive Meanwell(Founder)

Co-investorsALAlpha Wave GlobalARARCH Venture PartnersGVGV (Google Ventures)RARA CapitalSOSoftBank Vision FundVIViking Global+5 more

nChroma Bio develops in vivo targeted delivery and genetic engineering technologies for genetic medicine applications.

BiotechDeep TechMedical DevicesBoston, US

LGLuke Gilbert, PhD(Founder)Keith Joung, MD, PhD(Founder)DLDavid Liu, PhD(Founder)ALAngelo Lombardo, PhD(Founder)Luigi Naldini, MD, PhD(Founder)JWJonathan Weissman, PhD

Co-investorsATAtlas VentureNENewpath Partners5A5AM VenturesARARCH Venture PartnersDCDCVC (Data Collective)GVGV (Google Ventures)+11 more

Nocion Therapeutics develops small molecule charged sodium channel blockers (nocions) designed to silence overactive sensory nerves.

BiotechHealthtechMedical DevicesWatertown, US

MATTHEW FRANKEL(Executive Officer)inPCPETER COUROSSI(Executive Officer)RICHARD BATYCKY(President and Chief Executive Officer)JAMES ELLIS(Executive Officer)MLMICHAEL LIPP(Executive Officer)inCSCHRISTOPHER SILBER(Executive Officer)in

Co-investorsCACanaan PartnersLULumira VenturesMIMission BiocapitalMOMonograph Capital PartnersOUOUP (Osage University Partners)

Odaseva provides data management, backup, and protection tools built for large enterprises running Salesforce at scale.

Data & InfrastructureEnterprise SoftwareSaaSSan Francisco, US

SBSovan Bin(CEO and Founder)in

Co-investorsCRCRESCENT COVE CAPITALEIEight Roads VenturesPAPartech VenturesSESerenaEUEurazeoSESerena Capital

OnCusp Therapeutics develops oncology therapeutics for cancer treatment, including antibody-drug conjugates and small molecule compounds in clinical and preclinical stages.

BiotechMedical DevicesNew York, US

Dr. Bing Yuan(Co-Founder, Chief Executive Officer)Dr. Eric Slosberg(Co-Founder, Chief Development Officer)Dr. Andy Fu(Co-Founder, Chief Business Officer)Bing Yuan, Ph.D., MBA(Co-Founder, Chief Executive Officer)Eric Slosberg, Ph.D.(Co-Founder, Chief Development Officer)Andy Fu, PharmD, MBA(Co-Founder, Chief Business Officer)

Co-investorsOROrbiMedCACatalio Capital Management, LPSOSofinnova VenturesDEDe Novo VenturesINInsight PartnersNVNVIDIA

Quantum Circuits develops superconducting quantum computers using dual-rail qubits with built-in error detection, designed to accelerate the path to fault-tolerant quantum computing.

Advanced ManufacturingDeep TechHardwareQuantum ComputingMadison, US

RSRob Schoelkopf(Sterling Professor, Founder)inLFLuigi Frunzio(Founder)RSRay SmetsinMichel Devoret(Founder)Robert Schoelkopf(Founder)

Co-investorsARARCH Venture PartnersCACanaan PartnersCOConnecticut InnovationsFIFitz Gate VenturesINIn-Q-TelOUOUP (Osage University Partners)+2 more

Rippl delivers evidence-based dementia care through a combination of technology and human support for people living with dementia and their families.

Digital HealthHealthtechSeattle, US

KEKris Engskov(Co-founder & CEO)inRNRobert Nelsen(Co-Founder & Board Chair)Paul Engskov(Executive Officer, Director)

BoardHMHolly Maloney(Director)inIyah Romm(Director)Ryan Watts(Director)

Co-investors181843 CapitalARARCH Venture PartnersCICity LightEQEquitage Ventures, L.L.C.GEGeneral CatalystGVGV (Google Ventures)+2 more

Shift Bioscience develops siRNA therapeutics for cell rejuvenation, using a target identification platform that has identified an anti-fibrotic candidate initially aimed at liver fibrosis.

AI & Machine LearningBiotechLongevityCambridge, GB

DIDaniel Ives(Founder & CEO)inBSBrendan Swain(Co-founder & CSO)in

Co-investorsIKIKJ CapitalKIKindred CapitalCACambridge Innovation Capital

Space and Time provides blockchain indexing, secure offchain data, and zero-knowledge proofs for onchain financial applications.

Crypto & Web3Data & Infrastructure

Scott Dykstra(Founder)in

Co-investorsALAlliance DAO (ex DeFi Alliance)ALAlumni VenturesARArrington CapitalCICircle VenturesDIDigital Currency GroupETEterna Capital+12 more

Toku Eyes develops AI-driven solutions for eye health diagnostics and monitoring, bringing together medical expertise in endocrinology and ophthalmology with artificial intelligence capabilities.

AI & Machine LearningDigital HealthHealthtechMedical Devices

Michael V. McConnell(Chief Health Officer and Interim CEO)inFrancesca Logan(Chief Commercial Officer)inYariv Levin(Chief Compliance, Ethics and Clinical Affairs Officer)in

Co-investorsARArc AngelsICIcehouse VenturesOUOutset VenturesBLBlockchain CapitalFUFunders Club ManagementGMgmjp+8 more

Toku provides payroll infrastructure that lets companies pay teams in stablecoins, fiat, or tokens through a single API that integrates with existing systems like ADP, Gusto, and Workday.

Crypto & Web3Enterprise SoftwareFintechHR TechNew York, US

KOKenneth O'Friel(Founder)inDSDominika Stobiecka(Cofounder)in

Co-investorsBLBlockchain CapitalFIFirestreak VenturesWIWinklevoss CapitalFUFunders Club ManagementGMgmjpGRGradient Ventures+7 more

Toku is a cloud communications provider offering customer experience solutions, including a hosted contact centre (CCaaS) offering, to businesses.

AI & Machine LearningCloud ComputingEnterprise SoftwareSaaSSingapore, SG

TLThomas Laboulle(Founder)in

Co-investorsBEBetatron Venture GroupOSOSK Ventures InternationalBLBlockchain CapitalFUFunders Club ManagementGMgmjpGRGradient Ventures+7 more