Fundraising Fox

RiverVest Venture Partners

Venture capital

St. Louis · Pre-Seed–Late Stage · 23 people tracked

Also known as RiverVest Venture · RIVERVEST VENTURE MANAGEMENT LLC

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Investment thesis

RiverVest focuses on building life sciences companies, aiming to improve patient outcomes by backing innovation in biotechnology, pharmaceuticals, and medical technology. The firm supports entrepreneurs through a combination of scientific insight, strategic guidance, and operational involvement, and seeks to earn the trust of its investors. Its portfolio spans therapeutics areas such as neurodegenerative disease, rare liver diseases, and metabolic conditions like difficult-to-control type 2 diabetes, reflecting a deep-science approach to venture creation.

Source: firm website, verified Aug 25, 2026.

Stage
Pre-Seed–Late Stage
Check
$500K – $3M
HQ
St. Louis, Missouri, US
Leads rounds
Leads
Instruments
Equity
Founded
2000
Last 12 months
1 investment
AUM
$275M
VC funds
5
Tracked investments
69

Team · 23 people

from the firm's website & public directories
Alessandro Sette· Scientific Advisor; Professor and Member, La Jolla Institute for Immunology
Corrin Short· Executive Assistantin
Jared Rutter· Scientific Advisor; Professor of Biochemistry and HHMI Investigator, University of Utah
Jeff Seitz· Senior Analyst
Kelly Cathey· Director of Administration
Peter Tontonoz· Scientific Advisor; Professor of Pathology and Biological Chemistry, UCLA
Poppy Keller· Consultant

What they invest in

from 46 of 69 portfolio companies

Biotech ×35Healthtech ×26Medical Devices ×19Digital Health ×7Hardware ×2SaaS ×2AdTech ×1AgTech ×1

HQs:United States×34Mexico×1Vietnam×1

Who they back

founder profiles across 14 portfolio companies
86%
solo founders
12 of 14 mapped founding teams
~5 yrs
old at investment
median across 11 dated deals

Founding team size:solo founder×122 founders×2

Investments · 69 tracked

founders shown can be your intro path

By year:2026 · 12025 · 52024 · 12023 · 32021 · 32020 · 12019 · 12018 · 12017 · 22015 · 22014 · 222 dated

Spruce Biosciencessprucebiosciences.comin𝕏NASDAQ: SPRBAug 2020

Spruce Biosciences develops and commercializes therapies for serious neurological and endocrine disorders with unmet medical need, with a lead investigational enzyme replacement therapy (TA-ERT) for Mucopolysaccharidosis Type IIIB (Sanfilippo Syndrome Type B).

BiotechHealthtechSouth San Francisco, US

Javier Szwarcberg(Executive Officer, Director)Samir Gharib(Executive Officer)RICHARD KING(Executive Officer, Director)

BoardSimpson Camilla(Director)Tiba Aynechi(Director)inBali Muralidhar(Director)in

Board seatNiall O'Donnell· per SEC Form D

Co-investorsAisling CapitalHealthCapAbingworthNorwest Venture PartnersOrbiMed

Avalyn Pharma Incavalynpharma.cominNASDAQ: AVLNSep 2023 · $175M

Avalyn Pharma develops inhaled therapies for pulmonary fibrosis, using a nebulization approach that delivers treatment directly to the lungs to reduce the tolerability problems of existing oral therapies.

BiotechHealthtech

Lyn Baranowski(CEO)in

Co-investorsAndera PartnersCatalio Capital Management, LPF-Prime CapitalInVivium CapitalNorwest Venture PartnersSR One Capital Management+7 more

Macrogenics Incmacrogenics.cominNASDAQ: MGNX

MacroGenics is a clinical-stage biopharmaceutical company developing antibody-based therapies for cancer patients.

BiotechHealthtechMedical Devices

Co-investorsHavencrest Capital ManagementRidgeback CapitalSanofi Ventures

Mirum Pharmaceuticalsmirumpharma.comin𝕏NASDAQ: MIRM

Mirum Pharmaceuticals is a biopharmaceutical company that develops and delivers therapies for people living with rare diseases.

BiotechHealthtechSan Diego, US

Chris Peetz(Co-founder & Chief Executive Officer)inChristopher Peetz(Executive Officer, Director)Eric Bjerkholt(Executive Officer)Peter Radovich(Executive Officer)

BoardPatrick Heron(Director)Michael Grey(Director)

Co-investorsChiesi VenturesFrazier Life SciencesNew Enterprise Associates (NEA)Norwest Venture Partners

Onkure Therapeutics Inconkuretherapeutics.comin𝕏NASDAQ: OKUR

OnKure Therapeutics is a clinical-stage biopharmaceutical company developing PI3Kα pan-mutant selective inhibitor medicines for the treatment of breast cancer and vascular anomalies.

BiotechDigital HealthHealthtechMedical DevicesBoulder, US

Jason Leverone(Executive Officer)Samuel Agresta(Executive Officer)Dylan Hartley(Executive Officer)Nicholas Saccomano(Executive Officer, Director)Wendy Johnson(Executive Officer)

BoardIsaac Manke(Director)in

Co-investorsAccess BiotechnologyAbingworthACORN BIOVENTURESBoulder VenturesNew Enterprise Associates (NEA)

Xilio Therapeuticsxiliotx.cominNASDAQ: XLO

Xilio Therapeutics is a clinical-stage biotechnology company developing masked immuno-oncology therapies that use protein engineering to remain inactive until activated by tumor-specific proteases within the tumor microenvironment.

BiotechHealthtechWaltham, US

Rene Russo(Executive Officer, Director)inJoseph Farmer(Executive Officer)Timothy Clackson(Executive Officer)Paul Clancy(Director)Daniel Curran(Director)Nancy Hong(Director)

Co-investorsBain Capital Life SciencesBay City CapitalF-Prime CapitalM VenturesMRL Ventures FundRA Capital+4 more

Engrail Therapeuticsengrail.comin✓ verified

Engrail Therapeutics is a clinical-stage pharmaceutical company developing precision-targeted therapeutics for neupropsychiatric and neurodevelopmental disorders.

BiotechDigital HealthMedical DevicesSan Diego, US

Stephen(Co-founder, EVP Research & Development and Chief Development Officer)Paul Cayer(Chief Financial Officer)Vikram(President and Chief Executive Officer)Kimberly(Chief Scientific Officer)Quentin(Chief Technical Officer)

Co-investorsForesite CapitalLongwood FundNorwest Venture PartnersYsios Capitalabrdn plcEight Roads Ventures+4 more

Alleviant Medical Incalleviantmedical.comin𝕏Jan 2025

Alleviant Medical develops an investigational minimally invasive medical device using interatrial shunt therapy to treat heart failure patients, currently in FDA-approved clinical trials (ALLAY-HF and ALLAY-HFrEF).

BiotechHealthtechMedical DevicesAustin, US

Adam Berman(Executive Officer, Director)Jacob Kriegel(Executive Officer, Director)Avni Patel(Executive Officer, Director)Christopher Alex Arevalos(Executive Officer, Director)Albertien Greijdanus(Executive Officer, Director)

BoardGeoff Pardo(Director)

Board seatJay W. Schmelter· per SEC Form D

Co-investorsBroadview VenturesTMC Venture FundCadence Healthcare VenturesGilde HealthcareGilmartin Capital LLCS3 Ventures+1 more

Bonum Therapeuticsbonumtx.comin𝕏Apr 2026

Bonum Therapeutics develops antibody-controlled protein therapeutics that remain inactive until bound to their target, using a sensor-domain mechanism to deliver regulated, targeted activity.

BiotechHealthtechSeattle, US

John Mulligan(Executive Officer, Director, Promoter)inNeela Patel(Executive Officer)inDiane Hollenbaugh(Executive Officer)in

BoardSamuel Bjork(Director)inMonique Schiersing(Director)in

Board seatJohn McKearn· per SEC Form D

Co-investorsRoche Venture FundVivo Capital3x5 PartnersCodon CapitalDigitalis Ventures

Cardialen Inccardialen.comJul 2021

HealthtechSt. Louis, US

Igor R. Efimov(Director)M. Brent Shelton(Executive Officer)Paula Skjefte(Executive Officer, Director)Nick Lanners(Executive Officer)Igor Efimov(Director)

BoardEric A. Gulve(Executive Officer, Director)

Board seatJay W. Schmelter· per SEC Form D

Curzion Pharmaceuticals IncMar 2019acquired by Horizon Therapeutics

Acquired by Horizon Therapeutics in 2020.

BiotechSan Diego, US

Mike Grey(Executive Officer, Director)Susan Dube(Executive Officer)

BoardKyle Rasbach(Director)Johan Kordel(Director)Ed Mathers(Director)in

Board seatNiall O'Donnell· per SEC Form D

Co-investorsNew Enterprise Associates (NEA)

Genoa Pharmaceuticalsgenoa-pharmaceuticals.appspot.comOct 2023SEC filingmedium confidence

Avalyn Pharma (formerly Genoa Pharmaceuticals) is a biopharma company developing inhaled therapies for idiopathic pulmonary fibrosis (IPF) and other severe respiratory diseases.

BiotechHealthtechSan Diego, US

Mark W. Surber, Ph.D.(Executive Officer, Director)Richard G. Vincent(Executive Officer)

BoardMichael J. Kamdar(Director)Daniel D. Burgess(Director)

Board seatNiall O'Donnell· per SEC Form D · $189.2M raise · filed Oct 2023

Co-investorsNorwest Venture PartnersSofinnova Ventures

Intervene Incintervene-med.cominMar 2023

InterVene, Inc. is a medical device company that has developed a fully integrated mechanical thrombectomy system to treat venous in-stent restenosis and residual thrombotic venous obstructions and occlusions.

BiotechHealthtechMedical DevicesMountain View, US

Fletcher Wilson(Executive Officer, Director)

BoardThomas Fogarty(Director)Mel Schatz(Director)

Board seatJay W. Schmelter· per SEC Form D

Co-investorsLaunchCapitalTreo Ventures, LlcEmergent Medical Partners, LLP

Lyric PharmaceuticalsFeb 2015SEC filingmedium confidence

BiotechSouth San Francisco, US

David Wurtman(Executive Officer, Director)M. Scott Harris(Executive Officer)

BoardJason Hong(Director)Casey Cunningham(Director)Sanford Zweifach(Director)

Board seatNiall O'Donnell· per SEC Form D · $33.9M raise · filed Apr 2017

OncoResponseoncoresponseinc.comMay 2025 · $14M

Clinical-stage immuno-oncology company developing antibodies derived from the immune systems of 'Elite' cancer responders.

BiotechHouston, US

Alice Bexon(Executive Officer)Clifford J. Stocks(Director, Executive Officer)Kamal D. Puri(Executive Officer)Chris Russell(Executive Officer)Russ Hawkinson(Executive Officer)

BoardSteven Gillis(Director)in

Board seatJohn McKearn· per SEC Form D

Co-investors3B Future Health FundCanaan PartnersGreatPoint VenturesARCH Venture PartnersBering CapitalIntervest+3 more

Smart Wiressmartwires.comMay 2018SEC filingmedium confidence

EnergyOakland, US

James C David(Executive Officer, Director)Woody Gibson(Executive Officer)Stewart Ramsay(Executive Officer, Director)

BoardAnthony Arnerich(Director)Jay Schmelter(Director)inTony Arnerich(Director)

Board seatJay W. Schmelter· per SEC Form D · $85.8M raise · filed Jan 2020

Co-investorsEnergy Transition Ventures3x5 Partners

Sparrow Pharmasparrowpharma.comin𝕏Jul 2025

Sparrow Pharmaceuticals is a clinical-stage biopharmaceutical company developing targeted therapies for cardiometabolic disease.

BiotechHealthtechMedical DevicesPortland, US

Robert Jacks(Executive Officer, Director)David Aaron Katz(Executive Officer, Director)

BoardJonathan Root(Director)inZach Scheiner(Director)inKlaus Veitinger(Director)in

Board seatNiall O'Donnell· per SEC Form D

Co-investorsOrbiMedRA CapitalUS Venture Partners

Tryton MedicalJan 2017SEC filingmedium confidence

Durham, US

AARON V. KAPLAN(Director)SHAWN MCCARTHY(Director)Alejandro Sanchez(Director)Shawn P. McCarthy(Executive Officer, Director)Brett Farabaugh(Executive Officer)Aaron V. Kaplan(Director)

Board seatJay W. Schmelter· per SEC Form D · $8M raise · filed Feb 2017

VasculoxDec 2014SEC filingmedium confidence

BiotechSaint Louis, US

Kalthleen L. Beckmann(Executive Officer)Robert W. Karr(Executive Officer, Director)Pamela Manning(Executive Officer)William Frazier(Director)

BoardCharles Bolten(Director)

Board seatJohn T. McKearnJohn McKearn· per SEC Form D · $86.3M raise · filed Aug 2016

VentureMed GroupFeb 2025

HealthtechPlymouth, US

John Pigott(Executive Officer, Director)Jenny Zeroni(Executive Officer)Dave Michaelson(Executive Officer)Kathy Leith(Executive Officer)Jill Schweiger(Executive Officer)Shelby Hautman(Executive Officer)

Board seatKaren Spilizewski· per SEC Form D

Co-investorsEndeavour VisionS3 Ventures

Wugenwugen.comJul 2021 · $115M

Allotera (formerly Wugen) develops allogeneic T-cell therapies.

BiotechHealthtechMedical DevicesSt. Louis, US

Ayman Kabakibi(Executive Officer)Cherry Thomas(Executive Officer)Kumar Srinivasan(Executive Officer, Director)Keith Vendola(Executive Officer)Daniel M Kemp(Executive Officer, Director)Matthew Cooper(Executive Officer)

Board seatNiall O'DonnellJohn McKearn· per SEC Form D

Co-investorsAisling CapitalAlpha Wave GlobalBioGenerator VenturesAbingworthFidelity InvestmentsIntermediate Capital Group+1 more

Allakos Incallakos.comNov 2017

Portfolio company that completed a successful 2018 biotech IPO, resulting in a 9x return for RiverVest.

BiotechSan Carlos, US

Nenad Tomasevic(Executive Officer)Christopher Bebbington(Executive Officer, Director)Alejandro Dorenbaum(Executive Officer)

BoardFarah Champsi(Director)inJohn McKearn(Director)inPeter Moldt(Director)

Co-investorsAlta PartnersNew Enterprise Associates (NEA)Samsara BioCapitalRoche Venture Fund

Allotera Therapeuticsalloteratx.com

Co-investorsAisling CapitalLYZZ Capital

Amplyx PharmaceuticalsAug 2015

Developing broad-spectrum antifungal agents for invasive fungal infections.

BiotechSan Diego, US

Mitchell Mutz(Executive Officer, Director)

BoardChrysa Mineo(Director)Jack Florio(Director)Elaine Heron(Director)Santosh Vetticaden(Director)Karen Talmadge(Director)

Co-investorsNew Enterprise Associates (NEA)Pappas CapitalSofinnova VenturesSofinnova Venture Partners

Anacorin𝕏

Pfizer discovers, develops, manufactures, and distributes pharmaceutical medicines and vaccines across therapeutic areas including oncology, cardiology, immunology, and infectious diseases.

BiotechHealthtechMedical DevicesNew York, US

Charles Pfizer

Co-investorsAisling CapitalAndera PartnersRho Capital PartnersRho VenturesVenrockNew Enterprise Associates (NEA)

Arch Oncology Incarchoncology.com

Co-investorsAvego BioScience CapitalBioGenerator VenturesPerot Jain

Archmont Biopharma Inc
Atalantaatalantatx.comin𝕏Jan 2025 · $97M

Atalanta develops RNA interference-based therapeutics aimed at treating central nervous system and neurological diseases.

BiotechHealthtech

Co-investorsF-Prime CapitalNovartis Venture FundSanofi Venturesabrdn plcEQT Life Sciences

Biogen Idecbiogen.comin𝕏

Biogen is a biotechnology company founded in 1978 that focuses on breakthroughs in biology.

BiotechMedical Devices

Co-investorsAlpha Wave GlobalAsset Management Company

Biolinqbiolinq.comin

Biolinq develops the Shine sensor, a needle-free glucose monitor that measures glucose along with physical activity and sleep in a single wearable device.

Digital HealthHardwareMedical Devices

Jared Tangney(Founder)inRich Yangin

Co-investorsAble PartnersAlpha Wave GlobalAphelion CapitalAverin CapitalBOLD LongevityHikma Ventures+2 more

Biolinqbiolinq.mein

Biolinq develops a non-invasive glucose sensor that uses light to display glucose levels in real time, while also tracking activity and sleep to provide personalized health insights via a mobile app.

BiotechDigital HealthHealthtechMedical DevicesSan Diego, US

Jared Tangney(Executive Officer, Director, Promoter)inRichard Yang(Executive Officer, Director)Edward Kliphuis(Director)

BoardDaniel Bradbury(Director)inLana Ghanem(Director)

Co-investorsAlpha Wave GlobalBeyond CapitalBioBritJDRF T1D FundAphelion CapitalHikma Ventures+1 more

Bluejay TherapeuticsinMay 2024 · $182M

Healthcare company acquired by Mirum Pharmaceuticals, a former RiverVest portfolio company.

San Mateo, US

Keting Chu(Executive Officer, Director)Dajun Yang(Director)Nancy Hong(Director)Alon Lazarus(Director)William J. Rutter(Director)Ting Jia(Director)

Co-investorsFrazier Life SciencesRA CapitalHBM Healthcare InvestmentsNovo HoldingsT. Rowe PriceWellington Management

Cabrellisacquired by Pharmion

Portfolio company acquired by Pharmion, delivering a 6x return.

Cameron Health Inc
Centerre Healthcare Corporationlifepointhealth.netin

Lifepoint is a diversified healthcare delivery network operating community hospitals, rehabilitation and behavioral health hospitals, and additional sites of care across the healthcare continuum.

Digital HealthHealthtech

Scott Mercy(Founding Chairman and CEO)

Codeable Therapeutics
CV Therapeuticsgilead.comin𝕏

Gilead discovers, develops, and delivers innovative therapeutics for people with life-threatening diseases, focusing on virology, oncology, and inflammation across more than 35 countries.

BiotechDigital HealthHealthtechMedical DevicesFoster City, US

Lou Lange(Founder)Michael L. Riordan(Founder)inDaniel O'Dayin

Co-investorsAisling CapitalAsset Management CompanyFrazier Life SciencesKleiner PerkinsLongitude CapitalLumira Ventures+5 more

Cydex Pharmaceuticals Inccaptisol.comin

Captisol is a pharmaceutical-grade sulfobutylether beta-cyclodextrin (SBECD), a derivatized beta cyclodextrin used to solubilize and stabilize difficult-to-deliver molecules across routes such as parenteral, oral, ophthalmic, nasal, and inhalation.

BiotechHealthtechNew Materials

Epix Therapeuticsin

Medtronic designs and develops medical technology for treating complex diseases.

AI & Machine LearningDigital HealthHealthtechMedical Devices

Co-investors8VCCWRU Technology VenturesElevate VenturesMenlo VenturesOak Investment PartnersPfizer Venture Investments+5 more

Excaliard Pharmaceuticals Inc
Flex Vascularflexvascular.comin𝕏

FLEX Vascular makes the FLEX Vessel Prep System, an endovascular device that creates kinetic microincisions in a vessel prior to balloon angioplasty to treat difficult AVF and SFA lesions.

HealthtechMedical Devices

Gloucester Pharmaceuticalsbms.comin𝕏

Bristol Myers Squibb is a biopharmaceutical company that develops and delivers medicines across oncology, hematology, neuroscience, immunology, and cardiovascular disease areas.

BiotechHealthtechMedical DevicesNew York, US

Co-investorsKleiner PerkinsNew Enterprise Associates (NEA)Nextech InvestProspect Venture PartnersRho Capital PartnersRho Ventures+2 more

Glycomine

Developing therapies for congenital disorders of glycosylation combining replacement therapies with intracellular delivery vehicles.

BiotechSan Francisco, US

Christopher Starr(Director)Peter C.M. McWilliams(Director)Agnes Rafalko(Executive Officer, Director)

BoardGiacomo Chiesi(Director)

Co-investorsAdvent Life SciencesChiesi VenturesCTI Life Sciences Fund L.P.Remiges Ventures, Inc.Sanderling VenturesSanofi Ventures

Glycomine www.glycomine.comglycomine.comin𝕏

Glycomine develops therapeutics for rare diseases, many of which currently lack disease-modifying treatment options.

Biotech

Steven Axon(Chief Executive Officer)Hicham Alaoui(Chief Scientific Officer)Rose Marino(Chief Medical Officer)Peter McWilliams(Chief Business Officer)Geoffrey Hird(Chief Technology Officer)

Co-investorsAdvent Life SciencesMission Bay CapitalMission BiocapitalRemiges Ventures, Inc.Sanderling VenturesSanofi Ventures

Good Therapeuticsgoodtherapeutics.comin𝕏Dec 2021acquired by Roche

Portfolio company acquired by Roche.

BiotechSeattle, US

John Mulligan(Executive Officer, Director, Promoter)Mitchell Mutz(Director)Nicholas Walrod(Director)

BoardJohn McKearn(Director)inKarl Handelsman(Director)

Co-investorsDigitalis VenturesRoche Venture Fund

Idev Technologies Inc
InterVene Medical

RiverVest portfolio company where Andrew Kleiboeker holds a board observer seat.

Lumena Pharmaceuticalsin𝕏acquired by Shire

Acquired by Shire in 2014 (now part of Takeda).

BiotechMedical Devices

Co-investorsFrazier Life SciencesLongitude CapitalOberland Capital

Lutonix

Company founded by RiverVest that exited with an 8.0x gross return.

Maxwell Biomedicalmaxwellbiomedical.comin

Maxwell Biomedical develops a device-based alternative to catheter ablation for atrial fibrillation, using closed-loop adaptive left atrial multisite pacing and Spatial Resynchronization Therapy (SRT) to terminate AF without high-energy shock.

BiotechHardwareHealthtechMedical Devices

Randy Werneth(CEO, President)Timothy Corvi(Sr. VP, R&D)Derrick Chou(VP, Science & Technology)

Co-investorsBroadview Ventures

Mpex Pharmaceuticals Inchorizontherapeutics.ca
Myonid Therapeutics
Neuros Medicalneurosmedical.com

Neuros Medical develops the Altius Direct Electrical Nerve Stimulation System, an FDA-approved implantable device that delivers patient-controlled electrical stimulation to treat chronic post-amputation pain in adult lower limb amputees.

BiotechHealthtechMedical DevicesAliso Viejo, US

David Veino(President and CEO)Zach Stassen(Chief Financial Officer)Robert J. Centa(Chief Financial Officer)Jon J. Snyder(Director, President, Secretary and CEO)

BoardJoyce Erony(Director)inWilliam Harrington(Director)

Co-investorsAmzak HealthAPERTURE Venture PartnersCWRU Technology VenturesiSelect FundJobsOhio VenturesJumpstart Ventures+5 more

Outrigger
Oxalurx Inc
Reneo Pharmaceuticalsreneopharma.com

Xoilac TV is a free online football (soccer) live-streaming platform serving fans in Vietnam, offering Full HD match broadcasts of European, Asian, Vietnamese, and international competitions.

ConsumerMedia & EntertainmentSports Tech

Co-investorsAisling CapitalNew Enterprise Associates (NEA)AbingworthLundbeckfonden VenturesPappas Capital

Reneo Pharmaceuticals
Salient Surgical

Medical device company co-founded by Jay Schmelter; one of RiverVest's first two investments.

Scout Bio Incscoutbio.coin𝕏acquired by Ceva Santé Animale

Scout Bio developed biotechnology therapies for pets, including a pipeline of monoclonal antibodies and gene therapy programs targeting chronic diseases in companion animals.

AgTechBiotechDeep TechHealthtechPhiladelphia, US

Mark Hefferman(Executive Officer, Director)

BoardAditya Kohli(Director)inTadataka Yamada(Director)Patrick Heron(Director)inCindy Cole(Director)inNancy Hong(Director)

Co-investorsCompanion FundDigitalis VenturesFrazier Life Sciences

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

Exits · 11

IPOs and acquisitions across the tracked portfolio

Spruce BiosciencesNASDAQ: SPRBAvalyn Pharma IncNASDAQ: AVLNMacrogenics IncNASDAQ: MGNXMirum PharmaceuticalsNASDAQ: MIRMOnkure Therapeutics IncNASDAQ: OKURXilio TherapeuticsNASDAQ: XLOCurzion Pharmaceuticals Incacq. by Horizon TherapeuticsCabrellisacq. by PharmionGood Therapeuticsacq. by RocheLumena Pharmaceuticalsacq. by ShireScout Bio Incacq. by Ceva Santé Animale

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has RiverVest Venture Partners made?
RiverVest Venture Partners has 62 tracked investments, 5 of which have exited via acquisition or IPO, including 5 dated in the last 24 months.
What stage does RiverVest Venture Partners invest at?
RiverVest Venture Partners invests at the Pre-Seed, Seed, Series A, Series B, Series C, Growth, Late Stage stages.
What is RiverVest Venture Partners's typical check size?
RiverVest Venture Partners typically writes checks of $500K – $3M.
What sectors does RiverVest Venture Partners focus on?
RiverVest Venture Partners focuses on Biotech, Digital Health, Healthtech, Medical Devices.
Where is RiverVest Venture Partners located?
RiverVest Venture Partners is headquartered in St. Louis, US.
Does RiverVest Venture Partners lead rounds?
Yes, RiverVest Venture Partners leads investment rounds.
Who does RiverVest Venture Partners co-invest with?
RiverVest Venture Partners most often shares deals with New Enterprise Associates (NEA), Aisling Capital, Frazier Life Sciences, among 122 tracked co-investors.

Media · Podcasts & interviews

featuring the team

Tom Melzer, Managing Director & Co-Founder, RiverVest Venture Partners

InvestMidwest Venture Capital (Forum) · Tom Melzer

Co-investors · 21

New Enterprise Associates (NEA)

New Enterprise Associates (NEA) is a venture capital firm that invests in and provides long-term support to founders building new companies.

$200K – $40M
F-Prime Capital

F-Prime Capital is an early-stage-focused investment firm backing companies across life sciences, technology, healthtech and services, and crypto.

$3M – $10M
Sanofi Ventures

Sanofi Ventures is the corporate venture capital arm of Sanofi, investing in early-stage biotech and digital health companies focused on improving human health. It serves as Sanofi's entry point into the innovation ecosystem.

$5M
Abingworth

Abingworth is a life science venture capital firm that backs early-stage biopharma and biotech companies, helping entrepreneurs translate scientific discoveries into new therapeutics.

$15M – $30M
Digitalis Ventures

Digitalis Ventures invests in solutions to unmet needs in biomedicine and health, backing biotechnology and technology-enabled companies across human health and animal health.

$100K – $10M
Roche Venture Fund

Roche Venture Fund is a corporate venture arm that invests in early-stage biotech and diagnostics companies across more than 10 countries, with a portfolio exceeding 30 portfolio companies. The fund is headquartered in Basel, Switzerland.

$648K – $3.2M
OrbiMed

OrbiMed is a global healthcare-focused investment firm providing financing and operational support to companies across biopharmaceuticals, medical devices, digital health, diagnostics, and healthcare services.

$1M – $75M
S3 Ventures

S3 Ventures is a venture capital firm founded in 2005 that invests in technology companies and medical device/health software startups, backed by a single philanthropic limited partner.

$500K – $15M
Pivotal Life Sciences

Pivotal Life Sciences is an investment platform focused on funding innovative companies developing therapeutic products and technologies aimed at major unmet medical needs.

Advent Life Sciences

Advent Life Sciences is a trans-Atlantic venture capital firm investing in early and mid-stage life sciences companies across the UK, Europe and the USA.

Canaan Partners

Canaan Partners is a venture capital firm with over 30 years of history, backing companies across technology and healthcare sectors through close, hands-on partnerships with founders.

Both backed · 1
$500K – $20M
SR One Capital Management

SR One is a biotechnology-focused venture capital firm that partners with founders to develop innovative science into new medicines.

Both backed · 1
9 more co-investors

ForbionAlta PartnersCodon CapitalUnknown VenturesPolaris PartnersOUP (Osage University Partners)Deerfield Management CompanyDomain AssociatesFrazier Healthcare Partners

Firms observed investing alongside RiverVest Venture Partners, from public investor directories. Shared companies are the overlap with RiverVest Venture Partners's recorded portfolio.

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