Oxford · Pre-Seed–Growth · 82 people tracked
Find your way into Oxford Science Enterprises
2,240 people in our graph share verified history with the Oxford Science Enterprises team — schools, employers, funds. One of them is your warm intro.
Investment thesis
OSE partners with researchers and innovators across Oxford, Harwell and Culham to explore the commercial potential of cutting-edge science, co-create ventures and build companies. It backs Oxford's spinouts from pre-seed to growth, raising capital from global investors keen to access world-leading science and partnering with specialist co-investors to fund and scale portfolio companies. The firm focuses on deep tech, life sciences and healthtech, and has raised over £850m, with more than £3bn invested alongside co-investors.
Source: firm website, verified Aug 27, 2026.
Team · 82 people
from the firm's website & curated & public directoriesWhat they invest in
from 51 of 95 portfolio companiesDeep Tech ×32AI & Machine Learning ×20Biotech ×20Hardware ×16Medical Devices ×14Healthtech ×13Cleantech ×9Quantum Computing ×7
HQs:United Kingdom×29United States×2
Who they back
founder profiles across 21 portfolio companiesFounding team size:solo founder×92 founders×63 founders×24+ founders×4
Where their founders studiedfrom 20 founders with education data
University of Oxford ×9Imperial College London ×2
What their founders studiedfrom 22 founders with field-of-study data
Engineering ×7Physics ×7Chemistry ×3Computer Science ×3Life Sciences ×3Medicine ×2
Where their founders worked beforefrom 22 founders with career history
University of Oxford ×12Merton College ×2
18 founders hold a PhD (of 22 with degree data)
Investments · 95 tracked
founders shown can be your intro pathBy year:2026 · 42025 · 32024 · 12023 · 22022 · 42021 · 32019 · 118 dated
Barinthus Biotherapeutics is a clinical-stage biopharmaceutical company developing antigen-specific immunotherapies designed to guide T cells to treat autoimmune and inflammatory diseases.
BiotechHealthtechMedical Devices
Geoffrey Lynn(Chief Scientific Officer)William Enright(Chief Executive Officer & Board Director)Leon Hooftman(Chief Medical Officer)
Co-investorsGV (Google Ventures)Milltrust International GroupXfund
PepGen is a clinical-stage biotech company developing oligonucleotide therapies for neuromuscular and neurological diseases using its Enhanced Delivery Oligonucleotide (EDO) platform to improve tissue penetration and uptake in muscle tissues.
AI & Machine LearningBiotechHealthtechMedical DevicesBoston, US
James McArthur(Executive Officer, Director)inNoel P. Donnelly(Chief Financial Officer)inJoseph D. Vittiglio(Chief Business & Legal Officer and Secretary)inKasra Kasraian(Chief Technical Officer)in
BoardRamin Farzaneh-Far(Director)inJoshua Resnick(Director)
Co-investorsRA Capital
Beacon Therapeutics develops gene therapies for patients with serious diseases that lack or have limited treatment options, including investigational products like laru-zova for genetic conditions.
BiotechDigital HealthMedical Devices
Daniel Chung(Chief Medical Officer)inLance Baldo(Chief Executive Officer)inAbraham Scaria(Chief Scientific Officer)in
Co-investorsAdvent Life SciencesForbionTCG Crossover
Sereact builds AI foundation models that enable industrial robots to perform complex manipulation tasks like warehouse picking and returns handling without retraining.
Advanced ManufacturingAI & Machine LearningDeep TechEnterprise SoftwareQuantum ComputingRoboticsOxford, GB
Ralf Gulde(CEO and co-founder)Marc Tuscher(CTO and co-founder)Gerald Mullally(CEO)
Co-investorsAlpha EdisonBritish Business BankChevron Technology VenturesInvusBackstage AB
Dark Blue Therapeutics develops novel medicines for cancer through integrated drug discovery combining internal expertise with academic partnerships.
BiotechDeep TechHealthtechLondon, GB
Alastair MacKinnon(Chief Executive Officer)in
ModelLabs develops open microcavity sensing technologies for remote environmental monitoring.
AI & Machine LearningCleantechClimate TechDeep TechHardwareQuantum ComputingOxford, GB
Daniel Miles-Barrett(CTO)Prof. Jason Smith(Academic Founder)Dean James(CEO)in
OMass is a biotech company that originated as a spinout from Oxford University, developing specialized treatments for patient populations with high unmet medical needs.
BiotechDeep TechDigital HealthHealthtechMedical DevicesOxford, GB
Professor Dame Carol Robinson(Founder and Chair of Scientific Advisory Board)Idlir Liko(Founder)inJonathan Hopper(Vice President, Platforms and Founder)inHsin Yung (Jason) Yen(Founder)inRos Deeganin
Co-investorsGV (Google Ventures)Sanofi VenturesNorthpond Ventures
Opsydia develops optical and photonic technologies for precision manufacturing, emerging from research in adaptive optics and laser processing at the University of Oxford.
Advanced ManufacturingAI & Machine LearningDeep TechHardwareNew MaterialsSemiconductorsOxford, GB
Martin Booth(Founder and Director)inPatrick Salter(Founder and Director)inDr. Noel Moore(Chief Technology Officer)
BoardNigel Vaughan(Chairman)
Co-investorsForesight GroupOxford University InnovationParkwalk Advisors
Oxford Quantum Circuits (OQC) develops and operates superconducting quantum computers for commercial and strategic applications, offering Quantum-Compute-as-a-Service and integrating quantum systems directly into commercial data centres.
Deep TechEnterprise SoftwareHardwareQuantum ComputingOxford, GB
Peter Leek(Founder & CSO)inGerald Mullally(CEO)inSimon Phillips(CTO)inNikki Cooper(CLO)inRobert Coutts(CFO)in
BoardJack Boyer(Chairman of the Board)
Co-investorsBritish Business BankOxfordOxford Investment Consultants LLPUTEC
Refeyn develops mass photometry instruments that measure the mass of individual biomolecules in solution without labels, enabling analysis of protein purity, interactions, and viral vector characterization for research and manufacturing applications.
BiotechDeep TechHardwareMedical DevicesOxford, GB
Philipp Kukura(Founder)Dan Cole(Chief Scientist and co-founder)inJustin Benesch(Co-founder)in
Co-investorsHorizons VenturesOxford Technology Management
Seloxium develops a metal recovery and refining technology (branded "Selectal") used for tailings reprocessing, wastewater treatment, bulk metal recovery, and high-purity refining.
Circular EconomyCleantechDeep TechNew MaterialsTeesside, GB
Christian Peters(CEO & Co-founder)inSteve Colley(Co-founder, Technical Advisor & Director)Nick Hankins(Co-founder, Scientific Advisor & Director)Steve van Zutphen(Co-founder, CEO Advisor)Dr Richard Dixon(CCO)Roberto Ricci(CFO)in
Co-investorsOxford Investment Opportunity Network (OION)
Sitryx is a biotechnology company, founded in 2018, developing therapeutics with a focus on immunometabolism.
BiotechDeep TechHealthtech
Co-investorsLongwood FundSofinnova PartnersSV Health Investors
Snow Fox Discovery explores for and develops natural (geologic) hydrogen resources, aiming to supply low-carbon hydrogen for a net-zero energy transition.
CleantechClimate TechEnergy
Daniel McMahonin
Co-investorsAP VenturesOxfordbp ventures
Theolytics develops systemically deliverable immunotherapies based on oncolytic adenoviruses designed to target solid tumours and their supporting microenvironment.
BiotechHealthtech
Co-investorsEpidarex CapitalSound BioventuresTaiho Ventures, LLCM Ventures
Ultromics develops AI models that analyze routine echocardiography studies to help clinicians detect HFpEF and screen for cardiac amyloidosis, delivered through a single workflow platform.
AI & Machine LearningDigital HealthMedical Devices
Ross Upton(Founder & CEO)in
Co-investorsGV (Google Ventures)Legal & GeneralFuture Planet CapitalNina CapitalNovaCapitalOptum Ventures+2 more
AlveoGene develops respiratory gene therapies, led by executives and academic researchers from the UK Respiratory Gene Therapy Consortium.
BiotechDeep TechDigital HealthHealthtechMedical Devices
David Hipkiss(Executive Chair)in
Amber Therapeutics develops medical technology focused on treating mixed urinary incontinence, advancing toward pivotal clinical trials in the US with expanded feasibility studies in Europe.
Medical Devices
Co-investorsF-Prime CapitalIntuitive VenturesLightstone VenturesNew Enterprise Associates (NEA)
Archangel builds laser (optical) communication systems that connect satellite networks in space with terrestrial networks, offering an alternative to radio frequency and subsea cable infrastructure.
Deep TechHardwareSpace Tech
Co-investorsBlackfinch VenturesOxford
BibliU is a digital learning platform that partners with publishers to provide students affordable, instant access to course content, and offers institutions workflow automation to reduce administrative burden.
EdTechSaaS
Dave Sherwood(Co-Founder & CEO)in
Co-investorsBrick Capital VenturesGreen Shores CapitalGuinness VenturesParkwalk AdvisorsBeyond VenturesBlackRock+2 more
Co-investorsCreative Destruction Lab (CDL)Longwall Venture Partners LLPOxford Investment Consultants LLP
Diffblue offers an AI-powered solution that automatically generates Java unit tests, freeing developers from manual test writing.
AI & Machine LearningDeveloper ToolsEnterprise Software
Co-investorsAlbionVCPerivoli Innovations
Endlyz develops small-molecule disease-modifying therapeutics targeting the ATP13A2 and ATP10B lysosomal transporters to restore endo-lysosomal function and counter neurodegeneration.
BiotechDeep TechBoston, US
Joanna Wolak(Executive Officer, Director)inJonathan Behr(Director)John Gustofson(Director)Damian Crowther(Director)Zaven Kaprielian(Executive Officer, Director)
BoardLaurence Barker(Director)
Co-investorsDementia Discovery Fund
Evolito develops and manufactures electric propulsion and power generation systems for aerospace, including electric engines, motors, and motor control systems for type-certifiable and volume-manufactured applications.
CleantechHardwareMobility & Transportation
Co-investorsPerivoli Innovations
Evox Therapeutics develops exosome-based gene editing therapies using its ExoEdit platform, which combines exosome delivery with a proprietary CRISPR-based editor to treat severe neurodegenerative and other genetically-driven diseases.
BiotechDeep Tech
Co-investorsOrbiMedPanacea VentureCowen Healthcare InvestmentsGV (Google Ventures)REDMILE
First Light Fusion develops fusion energy technology through experimental validation of projectile-based fusion concepts and computational modeling for inertial confinement fusion applications.
CleantechDeep TechEnergyOxfordshire, GB
Yiannis Ventikos(Co-founder & Non-Executive Director)
Co-investorsSalica Investments
FluoRok, a spin-out of the University of Oxford, develops patented fluorinating technologies to produce fluorochemicals such as Li-ion battery electrolytes, agrochemicals, and pharmaceutical ingredients without generating toxic hydrofluoric acid.
CleantechDeep TechNew Materials
Gabriele Pupo(CEO & Founder)inVéronique Gouverneur(Founder)in
Co-investorsExcellis HoldingGGFGreen Generation FundClub degli Investitori
Fractile designs processors for AI acceleration, offering the next generation of computing hardware.
AI & Machine LearningDeep TechHardwareSemiconductorsBristol, GB
Walter Goodwin(Founder & CEO)in
Co-investors01 AdvisorsAccelFactorial FundsFelicis VenturesGigascale CapitalInovia Capital+3 more
Greywolf is a clinical-stage biotech developing antigen modulation therapies, including oral small molecules in Phase 1/2 trials, for people with cancers and autoimmune disorders.
BiotechDigital HealthHealthtechMedical DevicesOxford, GB
Peter Joyce(Co-founder)inTom McCarthy(Co-founder)in
Co-investorsAndera PartnersCanaan PartnersPfizer Venture InvestmentsBritish Patient CapitalEarlybird Venture CapitalPfizer Ventures
Living Optics develops hyperspectral imaging cameras and software that enable users to capture and analyze hidden details in images across applications in food, healthcare, security, and industrial markets.
AI & Machine LearningDeep TechHardwareMedical DevicesOxford, GB
Co-investorsOctopus Ventures
Marley Health combines veterinary and human healthcare expertise with machine learning and technology to develop healthcare solutions.
AI & Machine LearningConsumerHealthtechMedical Devices
Nate Notwell(Co-founder & CEO)Dr Amanda Boag(Co-founder & CMO)Dr Jenny Wilshaw(Co-founder & Head of Data)Prof David Clifton(Co-founder & Technology Advisor)
Mind Foundry develops deployed AI and machine learning systems for high-risk, high-complexity operational domains, including defense applications such as multi-sensor data fusion for battlespace situational awareness and threat-signature analysis.
AI & Machine LearningDeep TechDefense Tech
Stephen Roberts(Co-founder)inMichael Osborne(Co-founder)
Co-investorsParkwalk Advisors
Mixergy manufactures smart hot water cylinders with patented heating technology and machine learning controls that reduce energy consumption by up to 40%.
CleantechClimate TechEnergyHardwareIoTUK, GB
Co-investorsKiko Ventures
NavLive provides a handheld scanning device and cloud platform that captures point clouds and generates 2D floor plans, elevations, and sections in real time using multi-sensor SLAM tracking and AI feature detection.
AI & Machine LearningConstruction TechHardwarePropTech
David Wisth(Founder)in
Co-investorsClearance Venture PartnersOxford
Nucleome develops 3D genomics technology to map genetic variants in the non-coding genome to the genes they dysregulate, with applications in understanding inflammatory diseases and discovering therapeutic targets.
AI & Machine LearningBiotechDeep Tech
Co-investorsM VenturesPfizer Venture InvestmentsBritish Patient CapitalJJDCPfizer Ventures
ONI develops the Nanoimager, an automated super-resolution imaging system.
BiotechDeep TechHardwareMedical DevicesOxford, GB
Co-investorsARCH Venture PartnersArtis VenturesFuture Planet CapitalOxford Technology ManagementVertical Venture PartnersAxon Ventures+5 more
Orbit Discovery provides peptide discovery solutions for pharmaceutical and biotechnology companies, serving both large pharmaceutical firms and smaller biotech enterprises.
AI & Machine LearningBiotechDeep TechHealthtechOxford, GB
Co-investorsFuture Planet CapitalOxford Technology ManagementPerivoli InnovationsBorealis Ventures
ORCA Computing develops full-stack photonic quantum computing systems, including on-premises hardware and software tools, for research institutions, government bodies, and industry applications such as generative AI, machine learning, and optimisation.
AI & Machine LearningDeep TechHardwareQuantum ComputingLondon, GB
Ian Walmsley(Co-founder)inRichard Murray(Co-founder & CEO)inJosh Nunn(Co-founder & Chief Science Officer)inPer Nyberg(Chief Commercial Officer)inMike Piraino(Chief Operating Officer)Thien-An Nguyen(Chief Technology Officer)in
Co-investorsInnovating CapitalOctopus VenturesPerscitus LLPQuantonationVerve Ventures
Oxford Flow manufactures precision valves and regulators using a single-piston design for oil & gas, hydrogen, and water infrastructure.
Advanced ManufacturingCleantechEnergyHardwareOxford, GB
Co-investorsEnergy Impact PartnersFuture Planet Capitalbp ventures
Oxford Ionics develops trapped-ion quantum computers using proprietary Electronic Qubit Control technology, designed for businesses to deploy quantum computing applications.
Deep TechHardwareQuantum Computing
Co-investorsOxford University Innovation2xNLansdowne PartnersProsus Ventures
Oxford Semantic Technologies develops RDFox, an in-memory knowledge graph and semantic reasoning engine that uses logic-based inference to deduce new facts and deliver explainable, auditable results for AI applications.
AI & Machine LearningData & InfrastructureDeep TechOxford, GB
Ian Horrocks(Co-founder)inPeter Crocker(Founder)in
PQShield develops post-quantum cryptography (PQC) products, including optimized software libraries, SDKs, OpenSSL integration layers, and lattice-based hardware IP cores, to help organizations migrate systems to quantum-resistant cryptography.
CybersecurityDeep TechQuantum ComputingSemiconductors
Co-investorsBY Venture PartnersCrane Venture PartnersKindred CapitalAdditionChevron Technology Ventures
Prolific connects researchers, AI developers, and product teams with vetted participants for collecting high-quality human data for AI training, surveys, and behavioral research.
AI & Machine LearningData & InfrastructureEnterprise SoftwareMarketplacesSaaSLondon, GB
Phelim Bradley(Founder)in
Co-investors10xvaluepartnersY CombinatorPartech Ventures
Proxisense develops high-performance sensors for monitoring manufacturing processes and diagnostics, with origins in aerospace and defence applications.
Advanced ManufacturingDeep TechHardwareIoTMedical DevicesOxford, GB
Paul Vickery(Founder and Chairman)Kam Chana(Founder and NED)
Co-investorsFuture Planet CapitalParkwalk Advisors
Quantum Motion develops utility-scale quantum computers using silicon spin-qubit architecture compatible with standard semiconductor manufacturing processes and existing foundry supply chains.
Deep TechQuantum ComputingSemiconductors
Co-investorsBosch VenturesDCVC (Data Collective)Octopus VenturesRobert Bosch Venture CapitalSony Ventures CorporationBritish Business Bank+3 more
RQ Bio discovers and develops long-acting monoclonal antibodies (LAAbs) targeting seasonal influenza to provide protection against severe viral disease.
BiotechHealthtech
Co-investorsFrazier Life SciencesLifeArc VenturesEQT Life SciencesForbionRed Tree VentureWellington Management
Spin-out from the Universities of Oxford and Munster developing a novel semiconductor chip.
Vaysh Kewada(Founder)in
Co-investorsCambridge Innovation CapitalPerivoli InnovationsSilicon CatalystApplied VenturesDeeptech Labs
Scenic Biotech develops modifier therapy, a genetic medicine approach that targets secondary functions in the genome to neutralize the impact of disease-causing mutations.
AI & Machine LearningBiotechDeep TechDigital HealthHealthtech
Co-investorsBioMedPartnersEIR VenturesBioGeneration VenturesInkef
Scripta Therapeutics is a drug discovery company that maps and modulates transcription factors using AI/ML models and patient-derived disease models to identify novel therapeutics.
AI & Machine LearningBiotechDeep Tech
Co-investorsAlbionVCApollo Health Ventures
A biotech company dedicated to developing new vaccines, combining scientific expertise with commercial and operational capabilities.
BiotechDeep TechHealthtechMedical DevicesCambridge, GB
Mark Howarth(Co-founder)inSumi Biswas(President, Co-founder, Chief Scientific Officer)inSimon Draper(Co-founder)inJing Jin(Co-founder)in
Co-investorsGV (Google Ventures)
Stateful builds a decision intelligence engine that turns operational requirements into optimised, adaptive missions for mobile robots, coordinating single-robot, multi-robot, and human-robot operations across changing real-world environments.
AI & Machine LearningDeep TechRobotics
Kirsty Lloyd-Jukes(CEO & Co-Founder)inNick Hawes(Chief Scientist & Co-Founder)Bruno Lacerda(CTO & Co-Founder)inDavid Parker(Advisor & Co-Founder)
Co-investorsAmadeus Capital PartnersOxford University InnovationAmadeus Capital SA
T-Cypher Bio develops drugs with curative potential, focusing on antibody development, T cell biology, and TCR discovery.
AI & Machine LearningBiotechDeep Tech
Co-investorsFuture Planet CapitalLifeArc VenturesPerivoli Innovations
Tidal Cyber develops tools and services that help enterprises adopt MITRE ATT&CK framework for threat-informed defense.
CybersecurityEnterprise Software
Co-investorsAccess Venture PartnersBright Pixel CapitalDreamit VenturesGlasswing VenturesStoneMill VenturesTFX Capital+8 more
YASA develops axial flux electric motors ('eMotors') and control systems for electric vehicles and other electrification applications, using a proprietary Yokeless And Segmented Armature design that reduces motor size and weight while increasing power and torque density.
CleantechHardwareMobility & TransportationOxford, GB
Tim Woolmer(CTO & Founder)in
Co-investors24 HaymarketParkwalk AdvisorsInovia Capital
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Acionna TherapeuticsAlethio TherapeuticsAlethiotxAllosAlloyedApplied AtomicsAscensionBase GenomicsBeacon TherapeuticsCaudal EnergyCircadian TherapeuticsCredo TherapiesDensixDJS AntibodiesExposing cancer’s hidden vulnerabilitiesGenomicsGround Truth LabsHEXRIota Sciences SeedISOgenixKesmaleaKneu HealthLatent LogicMatchBioMirae HealthMiroBioMoa TechnologyNatcapOath SurgicalOdqa Renewable Energy TechnologiesORFonyxOsler DiagnosticsOxford EndovascularOxford NanoimagingPerspectumRinri TherapeuticsSalienceScriptaStronger, lighter, fasterThelior BioVivid Dx
Exits · 3
2 IPOs · 1 acquisitionsBarinthusbioNASDAQ: BRNSPepGenNASDAQ: PEPGYasaacq. by Mercedes Benz
Portfolio news
latest coverage across their companies
Archangel · startupdaily.net · Aug 17, 2026

First Light Fusion · stockpil.com · Aug 16, 2026

Bullhound Capital · alleywatch.com · Aug 13, 2026
Refeyn · refeyn.com · Aug 11, 2026
PepGen · tickerreport.com · Aug 8, 2026
Oxford Quantum Circuits · datacenterdynamics.com · Jul 27, 2026
Amber Therapeutics · foodsommelier.com · Jul 24, 2026
Frequently asked questions
- How many investments has Oxford Science Enterprises made?
- Oxford Science Enterprises has 95 tracked investments, 3 of which have exited, including 7 dated in the last 24 months.
- What stage does Oxford Science Enterprises invest at?
- Oxford Science Enterprises invests at the Pre-Seed, Seed, Series A, Series B, Series C, Growth stages.
- What is Oxford Science Enterprises's typical check size?
- Oxford Science Enterprises typically writes checks of $63.5K – $31.8M.
- What sectors does Oxford Science Enterprises focus on?
- Oxford Science Enterprises focuses on AgTech, AI & Machine Learning, Biotech, Cleantech, Climate Tech, Deep Tech, Energy, Healthtech, Medical Devices, Quantum Computing, Robotics, Sector Agnostic.
- Where is Oxford Science Enterprises located?
- Oxford Science Enterprises is headquartered in Oxford, GB.
- Does Oxford Science Enterprises lead rounds?
- Yes, Oxford Science Enterprises leads investment rounds.
- Who does Oxford Science Enterprises co-invest with?
- Oxford Science Enterprises most often shares deals with Future Planet Capital, Perivoli Innovations, Oxford, among 78 tracked co-investors.
Media · Podcasts & interviews
featuring the teamFII9: Ed Bussey – CEO, Oxford Science Enterprises
FII Institute · Ed Bussey
Ed Bussey, CEO of Oxford Science Enterprises, on the need for talent in the UK's spinout ecosystem.
Global Corporate Venturing · Ed Bussey
Ed Bussey, CEO, Oxford Science Enterprises
American European Business Association - AEBA · Ed Bussey
Bloomberg Talks: Oxford Science Enterprises CEO Ed Bussey | Bloomberg Talks
Bloomberg Podcasts · Ed Bussey
Images
Co-investors · 4
Parkwalk Advisors is a UK-based investment manager focused on backing deeptech companies spun out of UK universities, bridging the gap between academic research and commercial success. It operates as part of IP Group plc and is a leading EIS fund manager.
GV (Google Ventures) is a venture capital firm that has invested in artificial intelligence and machine learning since its early days, building a global portfolio of more than 100 AI companies across infrastructure, life sciences, and applications.
Apollo Health Ventures is a biotech-focused investor that combines traditional funding with venture building to back transformative healthcare and longevity companies in Europe and the US.
Borealis Ventures is a venture capital firm focused on building and backing healthcare companies.
Firms observed investing alongside Oxford Science Enterprises, from public investor directories. Shared companies are the overlap with Oxford Science Enterprises's recorded portfolio.
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