K2 HealthVentures
Venture debtBoston · Series A–Late Stage · 22 people tracked
Investment thesis
K2 HealthVentures backs innovative private and public companies across the life sciences and healthcare sectors, offering flexible, long-term capital tailored to companies' evolving needs throughout their lifecycles. Its investment professionals combine deep experience in healthcare finance and operations with scientific expertise. The firm's primary focus is customized debt financings, though it can also engage in equity and convertible structures thanks to a broad investment mandate and a permanent capital base. K2HV has committed over $1 billion in capital since inception, and emphasizes impact investing that supports underserved areas of healthcare.
Source: firm website, verified Aug 3, 2026.
Team · 22 people
from the firm's website & public directories
What they invest in
from 27 of 32 portfolio companiesHealthtech ×21Digital Health ×13Biotech ×11Medical Devices ×7AI & Machine Learning ×3InsurTech ×2Longevity ×2Mental Health ×2
HQs:United States×18
Investments · 32 tracked
founders shown can be your intro pathBy year:2022 · 22021 · 12020 · 25 dated
Alto Neuroscience is a precision psychiatry company developing personalized drug treatments for people with neuropsychiatric conditions, using neuroscience research and clinical data to match patients to appropriate therapies.
BiotechDigital HealthMental HealthMountain View, US
Amit Etkin(Founder)Adam Savitz(Executive Officer)Nicholas C. Smith(Executive Officer)Michael Hanley(Executive Officer)Aaron Weaver(Director)Po Yu (Jeff) Chen(Director)
Cartesian Therapeutics develops mRNA-based cell therapies for autoimmune diseases.
BiotechHealthtechWatertown, US
Metin Kurtoglu(Executive Officer)Chris Jewell(Executive Officer)Carsten Brunn(Executive Officer, Director)Emily English(Executive Officer)Blaine Davis(Executive Officer)Stephen Smolinksi(Executive Officer)
Neumora is a clinical research company developing investigational medications, with a focus on conducting clinical trials to obtain regulatory approval and make treatments available to patients.
BiotechDeep TechDigital HealthMedical DevicesWatertown, US
Matthew Fust(Director)Kari Stefansson(Director)Joshua Pinto(Executive Officer)Maykin Ho(Director)Alaa Halawa(Director)Tamara Tompkins(Executive Officer)
89bio is a clinical-stage biopharmaceutical company developing therapies for patients with liver and cardiometabolic diseases.
Biotech
Acumen is a biopharmaceutical company developing targeted therapies for Alzheimer's disease.
BiotechHealthtech
Alignment Health offers Medicare Advantage health insurance plans for Medicare beneficiaries, featuring 24/7 concierge services that schedule doctor appointments, arrange transportation, and answer healthcare questions in-person, in-home, or via mobile.
Digital HealthHealthtechInsurTech
Concert Health is a behavioral health medical group that integrates behavioral health into primary care using the Collaborative Care Model, employing clinicians to treat patients and measure outcomes.
Digital HealthHealthtechMental Health
Fuze Health provides technology-led healthcare services including disease screening, genomics, telehealth, digital pharmacy, and patient engagement to help partners deliver personalized care.
AI & Machine LearningDigital HealthHealthtech
BiotechSouth San Francisco, US
Jonathan Drachman(Director)Joanne Viney(Director)Joseph Bailes(Director)Ronald Hunt(Director)Andrew Robbins(Director)Mark Chin(Director)
Honest Health partners with primary care physicians to help them transition from fee-for-service to value-based care, focusing on Medicare populations.
Digital HealthHealthtech
Robert Bessler, MD(Chief Executive Officer and Board Member)Jason Howard(President)Greg Johnson, MD, MBA, CMD(Chief Medical Officer)Michael Feeney, MBA(Chief Financial Officer)Dave Crocker(Chief Information Officer)Aaron DeBoer, MBA(Executive Vice President)
Infusion for Health provides infusion and injection therapies delivered by nurses in private clinic suites or at patients' homes.
Digital HealthHealthtech
LetsGetChecked provides at-home health testing kits, telehealth consultations, and pharmacy services to consumers and organizations.
Digital HealthHealthtechMedical Devices
Dr. Robert Mordkin(Chief Medical Officer)
Longevity Health Plan is a Medicare Institutional Special Needs Plan (I-SNP) for adults in long-term care, primarily residents of skilled nursing facilities receiving nursing home level care.
Digital HealthHealthtechLongevity
Mighty Therapeutics is a biopharmaceutical company developing mitochondria-targeted medicines to treat mitochondrial dysfunction in rare genetic mitochondrial diseases and common age-related conditions.
BiotechHealthtechLongevityNeedham, US
Reenie McCarthy(CEO)
BiotechWaltham, US
Chrystiyna Bedrij(Director)Peter Bisgaard(Director)Vincent Cheung(Director)Laura Benjamin(Director)Benjamin Chen(Director)
Orthofix is a medical device company that develops orthopedic products including spine reconstruction and regenerative solutions, limb reconstruction hardware, surgical navigation systems, and non-invasive therapeutic and bracing solutions.
HardwareHealthtechMedical Devices
Integrated digital hub, pharmacy network, and script-level data to improve patient outcomes for brands.
Sidecar Health offers ACA-compliant major medical insurance plans for large employers, providing price transparency and direct access to care through fully insured and self-funded administrative services options.
HealthtechInsurTech
Patrick Quigley(Chief Executive Officer & Co-founder)Veronica Osetinsky(Chief Operating Officer & Co-founder)
Spark Pediatrics operates prescribed pediatric extended care (PPEC) medical daycare centers staffed by pediatric nurses and aides, providing all-day medical care, therapy, and a social setting for children with complex medical needs up to age 21.
Digital HealthHealthtech
ActaStim offers an FDA-approved electrical bone growth stimulation device used as an adjunct to lumbar spinal fusion surgery to improve fusion success and reduce failure rates.
HealthtechMedical DevicesManassas, US
Jon Christopher McAuliffe(Executive Officer)Jan A. Buck(Director)Kimball Chen(Director)Alex W. Evans(Director)Gary Grenter(Executive Officer, Director)Frithjof Fuchs(Director)
Umoja Biopharma develops in vivo CAR T cell therapies for cancer treatment using its VivoVec platform, which generates CAR T cells directly in patients' bodies.
BiotechDigital HealthMedical DevicesSeattle, US
Philip S. Low(Director)Irena Melnikova(Executive Officer)Anna French(Director)Robert Glassman(Director)Andrew M. Scharenberg(Executive Officer, Director)
BoardJohn Hamer(Director)
BiotechHealthtechCambridge, US
Bernat Olle(Executive Officer, Director)Daniel Couto(Executive Officer)Mark Mullikin(Executive Officer)Jeffrey Silber(Executive Officer)Bharatt Chowrira(Director)Christopher Viehbacher(Director)
Werewolf Therapeutics is a biotechnology company developing immunotherapy treatments for cancer.
BiotechHealthtechMedical DevicesWatertown, US
Daniel J. Hicklin(Founder, President, Chief Executive Officer, and Board member)Luke Evnin(Co-founder, Board member (Chairman))Daniel Hicklin(Executive Officer, Director)Alon Lazarus(Director)David Cordo(Executive Officer)
BoardChristoph Westphal(Director)
Exits · 3
IPOs and acquisitions across the tracked portfolioAlto NeuroscienceNYSE: ANROCartesian Therapeutics (NASDAQ: RNAC)NASDAQ: RNACNeumora TherapeuticsNASDAQ: NMRA
Portfolio news
latest coverage across their companiesGravie · pulse2.com · Aug 2, 2026
Phil · fortuneindia.com · Jul 17, 2026
Neumora Therapeutics · dailypolitical.com · Jul 16, 2026
Frequently asked questions
- What stage does K2 HealthVentures invest at?
- K2 HealthVentures invests at the Series A, Series B, Series C, Growth, Late Stage stages.
- What is K2 HealthVentures's typical check size?
- K2 HealthVentures typically writes checks of $10M – $100M.
- What sectors does K2 HealthVentures focus on?
- K2 HealthVentures focuses on Biotech, Digital Health, Healthtech, Longevity, Medical Devices.
- Where is K2 HealthVentures located?
- K2 HealthVentures is headquartered in Boston, US.
Similar investors
GV (formerly Google Ventures) is a venture investment firm that backs founders across many industries, aiming to build long-term relationships and support companies across multiple stages and milestones.
EQT Life Sciences, formerly LSP (Life Sciences Partners), is one of Europe's largest and most experienced life sciences investors, backing companies developing therapeutics, medical devices, diagnostics and healthtech.
Novo Holdings is the holding and investment company that manages the assets of the Novo Nordisk Foundation, serving as controlling shareholder of Novo Nordisk and Novonesis. It invests in life science companies across all stages and manages a diversified portfolio of equities, bonds, real estate, infrastructure and private equity.
Lumira Ventures is a North American life sciences venture capital firm that partners with mission-driven entrepreneurs to build companies developing and commercializing healthcare products for patients.
OrbiMed is a global healthcare-focused investment firm providing financing and operational support to companies across biopharmaceuticals, medical devices, digital health, diagnostics, and healthcare services.