Advent Life Sciences
Venture capitalActively deployingLondon · Seed–Late Stage · 28 people tracked
Also known as Advent Life Science Partners Llp · ADVENT LIFE SCIENCES LLP · Advent Ventures Life Sciences Llp
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Investment thesis
Advent Life Sciences backs early and mid-stage life sciences companies with a first-in-class or best-in-class approach, aiming to turn breakthrough science into approved medicines and medical products. Its investment focus spans new drug discovery across all modalities, medical technology, enabling technologies and vaccines. The firm typically invests as early as Seed or Series A and takes a hands-on approach, working in close partnership with management teams. Drawing on the team's entrepreneurial and investment experience, Advent aims to deliver superior financial returns by bringing innovation to patients. Since 2006, Advent-backed companies have brought numerous medicines and products to approval.
Source: firm website, verified Sep 29, 2026.
Team · 28 people
from the firm's website & curated & public directoriesFounder mafia
3 people who came through Advent Life Sciences went on to found or lead other companies.
What they invest in
from 40 of 86 portfolio companiesBiotech ×33Healthtech ×27Medical Devices ×18Digital Health ×7AI & Machine Learning ×4Deep Tech ×3Advanced Manufacturing ×2Hardware ×2
HQs:United States×21United Kingdom×5France×2Belgium×1Canada×1Finland×1
Who they back
founder profiles across 11 portfolio companiesFounding team size:solo founder×52 founders×43 founders×2
Investments · 86 tracked
founders shown can be your intro pathBy year:2026 · 12025 · 12024 · 32022 · 32021 · 12020 · 42019 · 22018 · 22017 · 32016 · 12015 · 22012 · 126 dated
X4 Pharmaceuticals is a biopharmaceutical company developing medicines for people living with rare immune disorders, including chronic neutropenia.
BiotechBoston, US
Mary DiBiase(Executive Officer)inChristophe Arbet-Engels(Executive Officer)inDavid Kirske(Executive Officer)inJohn Volpone(Executive Officer)inMark Baldry(Executive Officer)Adam Craig(Executive Officer, Director)in
Board seatAlan Walts· per SEC Form D · $1.2M raise · filed Jan 2015
Co-investorsBain Capital Life SciencesLumira VenturesNew Enterprise Associates (NEA)Partners ResoluteThynk CapitalOmega Funds+1 more
Agenus is a biotechnology company developing cancer immunotherapies, including its lead investigational combination of botensilimab (an anti-CTLA-4 antibody) and balstilimab (a PD-1 inhibitor), known as BOT+BAL.
BiotechHealthtechLexington, US
Garo Armen(Chairman & CEO, Co-founder)Ozer Baysal(Executive Officer)Robert Stein(Executive Officer)Christine Klaskin(Executive Officer)inKaren Valentine(Executive Officer)Steven O'Day(Chief Medical Officer)in
Co-investorsGrazia Equity GmbHHEALTHCARE ROYALTY PARTNERSOberland CapitalCommodore CapitalInvusLigand Pharmaceuticals+1 more
Aura Biosciences develops Virus-Like Drug Conjugates (VDCs), a platform using Virus-Like Particles conjugated with drugs or loaded with nucleic acids to target solid tumors.
BiotechHealthtechMedical DevicesCambridge, US
Elisabet de los Pinos, Ph.D.(Executive Officer, Director)Elisabet de los Pinos(Founder)inMichael Wyzga(Executive Officer)Dale Pfost, Ph.D.(Director)Alan E. Walts, Ph.D.(Director)Lewis Geffen(Executive Officer)
Co-investorsChiesi VenturesColumbus Venture PartnersDroia VenturesForesite CapitalJazzya InvestmentsMedicxi+4 more
Emergent BioSolutions is a public health company that develops, manufactures, and supplies medical countermeasures for national security and preparedness, along with commercialized products addressing threats such as the opioid epidemic.
Advanced ManufacturingBiotechHealthtechGaithersburg, US
Fuad El-Hibri(Director, Executive Officer)inRobert G Kramer(Executive Officer)inKatherine Strei(Executive Officer)Adam R Havey(Executive Officer)inDaniel J Abdun-Nabi(Executive Officer, Director)inJoseph C. Papa(President, CEO and Director)
Co-investorsOrbiMed
Shionogi is a pharmaceutical company that discovers and develops medicines for challenging human diseases, including antibiotics and treatments for HIV, influenza, and COVID-19.
BiotechHealthtech
Co-investorsSolas BioVentures
Beacon Therapeutics develops gene therapies for patients with serious diseases that lack or have limited treatment options, including investigational products like laru-zova for genetic conditions.
BiotechDigital HealthMedical Devices
Daniel Chung(Chief Medical Officer)inLance Baldo(Chief Executive Officer)inAbraham Scaria(Chief Scientific Officer)in
Co-investorsForbionOxford Science EnterprisesTCG Crossover
Levicept is a company in the life sciences sector with backing from prominent healthcare and pharmaceutical investors including Medicxi, Pfizer Ventures, Gilde Healthcare, and Advent Life Sciences.
BiotechHealthtechMedical Devices
Simon Westbrook(Founder and CSO)
Co-investorsGilde HealthcareIndex VenturesMedicxiPfizer VenturesPfizer Venture InvestmentsRedwood Ventures
Orphalan develops and commercializes innovative therapies for patients with rare diseases, with a focus on unmet medical needs where current treatments are limited or absent.
BiotechHealthtechImpact & Social GoodMedical DevicesParis, FR
Massimo BorieroinDmitry ParamonovinJohn FatuhiSandra BensoussaninAngelita BriffainOmar Camille Kamlin
Co-investorsBpifrance
Relief Cardiovascular develops transcatheter smart implant systems for volume management in congestive heart failure, including the Relief System, a preload-modulating implant for inferior vena cava flow modulation with autonomous hemodynamic monitoring.
BiotechHealthtechMedical DevicesCosta Mesa, US
Co-investorsBroadview VenturesGood Growth CapitalVensana Capital
Tridek-One Therapeutics develops bispecific antibodies that agonize the CD31 ITIM inhibitory checkpoint receptor to modulate immune cell activation for inflammatory and autoimmune diseases.
BiotechDeep TechHealthtechParis, FR
Co-investorsBioqube VenturesBpifrancePureos BioventuresAdBio partners
Arrakis Therapeutics develops RNA-targeted small-molecule (rSM) medicines, working independently and with partners to create drug candidates aimed at the root causes of disease.
AI & Machine LearningBiotechDeep TechHealthtechCambridge, US
Michael Gilman(Executive Officer, Director)inMark DeLong(CEO)inDavid Neafus(Executive Officer)inRussell C. Petter(Executive Officer)
BoardColleen Cuffaro(Director)inAlan E. Walts(Director)in
Board seatRaj ParekhAlan Walts· per SEC Form D
Co-investorsCanaan PartnersPfizer VenturesHBM Healthcare InvestmentsHBM PartnersNextech InvestOUP (Osage University Partners)+3 more
Artax Biopharma is a Phase 2 clinical-stage biotechnology company developing first-in-class oral small-molecule Nck modulators that target T cell receptor Signal 1 activation to treat autoimmune diseases without causing immunosuppression.
BiotechHealthtechCambridge, US
Damia Tormo(President, CEO, Treasurer and Founder)inJoe Suarez(Executive Officer)Maria Nichol(Executive Officer)inRobert W. Armstrong, Ph.D.(Executive Officer, Director)Rob Armstrong(CEO)in
BoardAndre Hoekema(Director)
Board seatRaj ParekhAlan Walts· per SEC Form D
Co-investorsSound BioventuresColumbus Venture Partners
Uses a T-cell antigen discovery platform to develop vaccines for oncology and infectious disease.
BiotechCambridge, US
Narinder Singh(Executive Officer)Derek Meisner(Executive Officer)inMichael Alfieri(Executive Officer)Jessica Flechtner(Executive Officer)Girish Aakalu(Executive Officer)Thomas Davis(Executive Officer)
Board seatKatrine Bosley· per SEC Form D · $15M raise · filed Feb 2019
Co-investorsCycad Group LLCLux CapitalMC Healthcare VenturesAlexandriaAuriga PartnersBill & Melinda Gates Foundation+1 more
BiotechWatertown, US
Edward Mascioli(Executive Officer)Andrew Myers(Director)
BoardMarkus Goebel(Director)Henry Skinner(Director)inVikas Goyal(Director)
Board seatRaj Parekh· per SEC Form D
Co-investorsGurnet Point CapitalNovartis Venture FundRoche Venture Fund
HealthtechFremont, US
Anton Clifford(Executive Officer)inJames Leech(Executive Officer)inChristopher Gleason(Executive Officer)inKevin K. Sidow(Executive Officer, Director)
BoardJoshua Makower(Director)
Board seatShahzad Malik· per SEC Form D
Co-investorsLightstone VenturesNew Enterprise Associates (NEA)Runway Growth CapitalGBS Venture Partners Ltd.Gilde HealthcareVertex Ventures HC
HealthtechCarlsbad, US
Christoph Scharf(Director)inRandy Werneth(Executive Officer, Director)Graydon Beatty(Executive Officer)inVince Burgess(Director)inJohn Dahldorf(Executive Officer)
BoardAditya Puri(Director)
Co-investorsOrbiMedXeraya CapitalDeerfield Management CompanyFormation GroupGE VenturesIndex Ventures
Algeta was a Norwegian oncology company developing alpha-particle radiopharmaceuticals, notably Xofigo (radium-223 dichloride) for bone metastases in prostate cancer.
Co-investorsBirk VentureHealthCapAbingworth
AlphaRose develops genetic technologies and treatments for children with rare genetic diseases, aiming to make and commercialize such medicines at scale.
BiotechHealthtech
Co-investorsSuncoast Ventures
Amphista Therapeutics develops next-generation targeted protein degradation (TPD) medicines using its proprietary Targeted Glue technology, which is engineered to selectively trigger the destruction of disease-causing proteins.
BiotechCambridge, GB
Louise Modis(Chief Executive Officer)inMartin Pass(Chief Development Officer)inGiles Brown(Executive VP Drug Discovery)in
Co-investorsNovartis Venture FundSV Health InvestorsDementia Discovery FundEuropean Investment FundForbionGilde Healthcare+2 more
BiotechHouston, US
Amato Giaccia(Director)Rudy Howard(Chief Financial Officer)Robert B. Geller(Chief Medical Officer)inGail McIntyre(Chief Executive Officer)Leonard Scott Dove(Chief Operating Officer)Joshua Brumm(Executive Officer)
Co-investors3E Bioventures CapitalEshelman Ventures, LLC
Argá Medtech is developing a non-thermal cardiac ablation system based on a proprietary Pulsed Field Ablation (PFA) technology using sine wave energy and a proprietary catheter to treat atrial fibrillation and other heart arrhythmias.
HardwareHealthtechMedical Devices
Co-investorsEarlybird Venture CapitalGilde Healthcare
AviadoBio is a biotech company focused on frontotemporal dementia (FTD), a form of early-onset dementia.
BiotechHealthtechMedical Devices
David Cooper(Chief Medical Officer)Farah Speer(SVP, Communications and External Relations)
AviadoBio is a gene therapy company developing adeno-associated viral (AAV) treatments for neurodegenerative disorders such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
BiotechDeep TechDigital HealthHealthtech
Chris Shaw(Co-Founder & Chief Scientific and Clinical Advisor)inDo Young Lee(Co-Founder)Youn Bok Lee(Co-Founder)inLisa Deschamps(Chief Executive Officer)inGraeme Fielder(Chief Operating Officer)inAlex Bloom(Chief Development Officer)in
Co-investorsDementia DiscoveryF-Prime CapitalLifeArc VenturesMonograph Capital PartnersNew Enterprise Associates (NEA)
Boston Scientific develops medical devices and technologies used by healthcare professionals to treat patients across a range of conditions.
HealthtechMedical DevicesIrvine, US
Michael Williamson(Executive Officer)Dan L. Dearen(Executive Officer)inRaymond Cohen(Executive Officer, Director)in
BoardDarren Cai(Director)Raphael Wisniewski(Director)Erik Amble(Director)
Co-investorsAndera PartnersLongitude CapitalGilde Healthcare
Centessa is a biopharmaceutical company developing an Orexin Receptor 2 Agonist program aimed at treating sleep-wake, neurological, neurodegenerative, and neuropsychiatric disorders.
BiotechHealthtech
Co-investorsEcoR1 CapitalForesite CapitalLifeSci Venture PartnersMedicxiOberland CapitalScion Life Sciences+3 more
Cyted Health develops diagnostics for earlier and more accurate detection of esophageal disease, including its EndoSign capsule sponge cell collection device and molecular diagnostics, intended for clinicians screening for conditions such as Barrett's Esophagus and esophageal cancer.
BiotechHealthtechMedical Devices
Co-investorsEQT Life Sciences
Epitopea develops off-the-shelf cancer vaccines targeting aberrantly expressed tumor-specific antigens using its proprietary CryptoMap platform.
AI & Machine LearningBiotechHealthtechMontreal, CA
Claude PerreaultPierre Thibault
Co-investorsCambridge Innovation CapitalCTI Life Sciences Fund L.P.adMare BioInnovationsFonds de solidarité FTQ
F2G develops medicines to treat serious fungal diseases where existing therapies have failed or are ineffective.
BiotechDigital HealthHealthtechMedical Devices
Co-investorsAisling CapitalAMR Action FundAstellas Venture Management LLCBrace PharmaSofinnova PartnersSunstone Capital+3 more
Glycomine develops therapeutics for rare diseases, many of which currently lack disease-modifying treatment options.
BiotechSan Francisco, US
Agnes Rafalko(Executive Officer, Director)inSteven Axon(Chief Executive Officer)inHicham Alaoui(Chief Scientific Officer)inRose Marino(Chief Medical Officer)inPeter McWilliams(Chief Business Officer)Geoffrey Hird(Chief Technology Officer)in
Co-investorsChiesi VenturesCTI Life Sciences Fund L.P.Mission Bay CapitalMission BiocapitalRemiges Ventures, Inc.RiverVest Venture Partners+5 more
Iterum Therapeutics develops anti-infective compounds to treat infections caused by multi-drug resistant pathogens.
BiotechDigital HealthHealthtechMedical DevicesDublin, US
Michael W. Dunne(Executive Officer, Promoter)inCorey N. Fishman(Executive Officer, Director, Promoter)inJudith M. Matthews(Executive Officer, Promoter)Jeff Schaffnit(Executive Officer)
BoardBrenton K. Ahrens(Director)Ronald M. Hunt(Director)
Co-investorsBay City CapitalCanaan PartnersSofinnova VenturesDolby Family VenturesFrazier Life SciencesSofinnova Venture Partners
Little Dog Communications is a biotech communications firm that helps life science companies translate complex scientific and technical concepts into clear narratives for investors, media, and other stakeholders.
BiotechMarketing TechSan Diego, US
Jessica Yingling(Ph.D., President)
Nalu Medical develops a non-integrated neurostimulation system that uses electrical impulses to interrupt pain signals for patients with intractable chronic nerve pain.
HardwareHealthtechMedical DevicesCarlsbad, US
Earl Fender(President & CEO)inLee Hartley(Executive Officer)inAllen Meacham(Executive Officer)inBick Sellers(Executive Officer)inThomas A. West(Executive Officer, Director)inJeffrey Swiecki(Executive Officer)
Co-investorsAPERTURE Venture PartnersB Capital GroupB4 CapitalDecheng CapitalEndeavour VisionLongitude Capital+2 more
Co-investorsFountain Healthcare PartnersOrbiMedColumbus Venture PartnersForbionRedwood Ventures
Pheno Therapeutics is a clinical-stage biotech company developing GPR17 antagonists that target oligodendrocytes to promote brain repair.
BiotechMedical DevicesEdinburgh, GB
Neil Carragher(Founder)in
Co-investorsLifeArc VenturesOld College Capital
BiotechBoston, US
Dr. Richard Peters(Director)Belinda Termeer(Director)Dr. Alan E. Walts(Director)inDr. Gerhard Wagner(Director)Sun Altbach(Executive Officer, Director)in
Co-investorsLumira VenturesOrbiMed
Proximie provides a cloud-based operating system for connected operating rooms, giving medtech companies and hospitals real-time OR connectivity, structured surgical data, and AI-driven insights.
AI & Machine LearningDigital HealthMedical DevicesSaaSAltrincham
Nadine Haram(Director)inNadine Hachach-Haram(Founder)inJonathan Lim(Director)inScott Huennekens(Director)in
BoardMohammed Shahzad Ahmed Malik(Director)
Co-investorsCapria VenturesCedar Mundi VenturesCOTU VenturesDraper AssociatesF-Prime CapitalQuesta Capital+5 more
Purespring develops genetic therapies targeting podocytes to treat renal diseases through its proprietary GlomThera platform.
BiotechDigital HealthHealthtechMedical Devices
Moin Saleem(Co-founder & Chief Scientific Advisor)in
Co-investorsSofinnova PartnersForbionGilde HealthcareBritish Patient Capital
Rappta Therapeutics develops small molecule compounds that reactivate protein phosphatase 2A (PP2A) to treat cancer by restoring the enzyme's tumor suppressor function.
AI & Machine LearningBiotechHealthtechMedical Devices
Co-investorsNovartis Venture FundNovo Holdings
Boston-based biotech developing drugs against the 'dark genome'/repeatome for autoimmune disease, cancer and neurodegeneration.
Co-investorsAndreessen HorowitzARCH Venture PartnersGV (Google Ventures)Luma GroupSanofi VenturesAbingworth+11 more
uniQure is a biotech company developing gene therapies for serious genetic diseases.
BiotechHealthtechMedical Devices
Co-investorsForesite CapitalHEALTHCARE ROYALTY PARTNERSRidgeback Capital
Co-investorsAisling CapitalSofinnova Ventures
Zyme Communications provides PR and marketing services to life science companies across Europe and the USA, helping them build visibility with investors, commercial partners, and customers through specialized communications and media outreach.
BiotechMarketing TechSaaS
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
AcutusALETAArtaxAuraAvananAvilaAxonics Modular TechnologiesBeaconBeacon TherapeuticsCardiacAssistCardiAQCardiAQ Valve TechnologiesCardiokineCellnovoCn CreativeConatusCurveEloxxEmergentEUSAEUSA PharmaHighlightInfinityInfinity PharmaceuticalsIterumKaNDyKaNDy TherapeuticsKuDosMicrometMiroBioNeRRePhenoPICPowderMedRespivertSantarusSEPThiakisTridek-OneVentusVentus MedicalVestagen Technical TextilesWondr Medical
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Exits · 16
5 IPOs · 11 acquisitionsX4 PharmaNASDAQ: XFORAgenusNASDAQ: AGENAura BiosciencesNASDAQ: AURAEmergent BiosolutionsNYSE: EBSShionogiOTC: SGIOFAlgetaacq. by BayerCardiAQacq. by Edwards LifesciencesCardiAQ Valve Technologiesacq. by Edwards LifesciencesCardiokineacq. by Cornerstone TherapeuticsConatusacq. by HISTOGEN INC.EUSAacq. by Jazz PharmaceuticalsMicrometacq. by AmgenPowderMedacq. by PfizerRespivertacq. by Centocor Ortho Biotech (Johnson & Johnson)Santarusacq. by Salix PharmaceuticalsThiakisacq. by Wyeth Pharmaceuticals
Portfolio news
latest coverage across their companiesAgenus · simplywall.st · Aug 15, 2026
Zyme Communications · zymecommunications.com · Jul 29, 2026
Arrakis Therapeutics · biospace.com · Jun 25, 2026
Nalu · trysignalbase.com · Mar 25, 2026
Purespring · purespringtx.com · Oct 4, 2025
Principals & officers · per Companies House
what is this? ⓘLLP designated member · since 2009
LLP designated member · since 2009
LLP member · since 2010
LLP member · since 2010
LLP member · since 2011
LLP member · since 2013
LLP member · since 2011
LLP member · since 2009
LLP member · since 2012
LLP member · since 2012
+7 more officers on the register
Rajesh Bhikhu Parekh — 25–50% of voting rights, right to share surplus assets 25 to 50 percent limited liability partnership
Mohammed Shahzad Ahmed Malik — 25–50% of voting rights, right to share surplus assets 25 to 50 percent limited liability partnership
IPO stake values · per SEC filings
Value of this firm's stake in each portfolio company at its IPO price, from the prospectus principal-stockholder table.
| Company | Owned | IPO price | At IPO | Stake value |
|---|---|---|---|---|
| Aura Biosciences | 6.5% | $14.00 | Nov 2021 | $25.8M |
Source: SEC S-1 / 424B prospectus filings. Stake value = shares beneficially owned × the initial public offering price, as disclosed — a market value at IPO, not a return multiple (the firm's original cost is not disclosed).
Frequently asked questions
- How many investments has Advent Life Sciences made?
- Advent Life Sciences has 86 tracked investments, 16 of which have exited, including 3 dated in the last 24 months.
- What stage does Advent Life Sciences invest at?
- Advent Life Sciences invests at the Seed, Series A, Series B, Series C, Growth, Late Stage stages.
- What sectors does Advent Life Sciences focus on?
- Advent Life Sciences focuses on Biotech, Digital Health, Healthtech, Longevity, Medical Devices.
- Where is Advent Life Sciences located?
- Advent Life Sciences is headquartered in London, GB.
- Who does Advent Life Sciences co-invest with?
- Advent Life Sciences most often shares deals with OrbiMed, F-Prime Capital, Foresite Capital, among 75 tracked co-investors.
- What size deals does Advent Life Sciences back?
- Across 9 deals with disclosed amounts, Advent Life Sciences has joined rounds of $3M – $120M (median $29M).
Images
Co-investors · 24
Forbion is a global venture capital firm focused on advancing biotech innovations and other sustainable solutions aimed at improving human and planetary health.
OrbiMed is a healthcare-focused investment firm providing tailored financing solutions and global resources to build world-class healthcare companies across biopharmaceuticals, medical devices, digital health, diagnostics, and healthcare services.
F-Prime Capital is an early-stage-focused investment firm backing companies across life sciences, technology, healthtech and services, and crypto.
The Novartis Venture Fund invests in innovative life science companies, primarily in biotechnology and biopharmaceuticals, at various stages of development across North America and Europe.
Abingworth is a life science venture capital firm that backs early-stage biopharma and biotech companies, helping entrepreneurs translate scientific discoveries into new therapeutics.
Columbus Venture Partners is a Spanish life sciences venture firm that invests in therapeutic and industrial biotech products through its life science funds, aiming to advance healthcare while generating returns.
Canaan Partners is a venture capital firm with over 30 years of history, backing companies across technology and healthcare sectors through close, hands-on partnerships with founders.
Pureos Bioventures is a venture capital firm that invests in private, innovative drug development companies, with a focus on next-generation biological drugs and drug formats to treat severe diseases.
Broadview Ventures is an impact investor focused on accelerating the development of technology for the diagnosis and treatment of cardiovascular disease and stroke through targeted investments.
Polaris Partners is a venture capital firm that partners with biotech and healthcare entrepreneurs to build transformational companies.
Atlas Venture is a life sciences venture capital firm with three decades of experience investing in and building biotech and medical innovation companies, including startups launched from its own incubator.
ARCH Venture Partners is a venture capital firm that invests in and helps build transformational companies, with a strong focus on the life sciences and biotechnology sector.
▶12 more co-investors
GE VenturesEQT Life SciencesDolby Family VenturesRiverVest Venture PartnersSamsara BioCapitalQuesta CapitalSR One Capital ManagementJohnson & Johnson Innovation – JJDCSparkLabs Global VenturesBusiness Growth FundJMI EquityAberdare Ventures
Firms observed investing alongside Advent Life Sciences, from public investor directories. Shared companies are the overlap with Advent Life Sciences's recorded portfolio.
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