SignalFire
San Francisco · Seed–Series C · 40 people tracked
Investment thesis
SignalFire invests in early-stage companies and differentiates through deep operational support beyond traditional venture services. The firm leverages proprietary AI/ML tools (Beacon AI platform), data analytics, structured advisory programs, and in-house sector expertise to help founders scale. The firm emphasizes a product-oriented approach to founder support and positions itself as a technology-enabled venture investor.
Source: firm website, verified Jul 19, 2026.
Team · 40 people
from the firm's websiteWhat they invest in
from 19 of 20 portfolio companiesAI & Machine Learning ×12Enterprise Software ×10SaaS ×10Data & Infrastructure ×6Developer Tools ×5Healthtech ×4Fintech ×3Sales Tech ×3
HQs:United States×8Germany×1
Investments · 20 tracked
founders shown can be your intro pathGreybeam builds a compute layer that optimizes query costs for data warehouses, reducing expensive cloud database usage by routing queries away from data warehouses when more efficient alternatives exist. The platform serves organizations using AI-driven workflows and automated agents that query databases at scale, helping them achieve significant cost reductions without migration or code changes.
AI & Machine LearningCloud ComputingData & InfrastructureSaaS
Lago is an open-source billing platform that enables companies to build and manage their billing infrastructure with transparency and control. The platform serves tech companies that need flexible billing solutions without the limitations of third-party black-box systems.
Developer ToolsEnterprise SoftwareFintechSaaSSan Francisco, US
Anh-Tho CHUONG(Founder)inRaffi SARKISSIAN(Founder)inAnh-Tho Chuong(CEO & co-founder)Raffi Sarkissian(CPO & co-founder)
Centaur.ai uses performance-based AI and collective intelligence methods to improve medical decision-making in skin lesion assessment for cancer detection. The company combines expert human judgment with AI algorithms weighted by demonstrated accuracy rather than credentials.
AI & Machine LearningData & InfrastructureHealthtechMedical DevicesBoston, US
Erik Duhaime(Founder)inTom Gellatly(Founder)inZach Rausnitz(Founder)in
Centaur.ai combines human medical professionals' assessments with AI algorithms to improve diagnostic accuracy for skin lesion evaluation and cancer detection. The platform weights opinions based on performance metrics to achieve results superior to either doctors or AI alone.
AI & Machine LearningData & InfrastructureDigital HealthHealthtechMedical Devices
Erik Duhaime
Formant Metaphysics is an AI-powered incident management and ticketing system designed for physical operations in industrial settings. It consolidates institutional knowledge, manages alarms, and enables predictive maintenance for enterprise fleets using goal-oriented agents and generative AI.
AI & Machine LearningEnterprise SoftwareIoT
Freshpaint provides a platform for healthcare marketers to securely connect and activate customer data across marketing channels while maintaining privacy compliance. The platform helps healthcare organizations measure marketing performance, optimize spending, and scale growth within regulatory constraints.
Data & InfrastructureDeveloper ToolsDigital HealthEnterprise SoftwareHealthtechMarketing TechSaaSSan Francisco, US
Steven Fitzsimmons(Founder)inMichael Malis(Founder)inRay Mina(Chief Executive Officer)inTom Spiegelman(Chief Product & Technology Officer)in
Grow Therapy provides online mental health therapy services designed to be more accessible, affordable, and user-friendly than traditional therapy. The platform connects patients with therapists and works with insurance companies and employers to expand mental health access.
B2B MarketplacesHealthtechMental HealthSaaS
Karat conducts technical interviews and evaluates engineering talent for organizations, providing workforce intelligence through expert-led assessments and AI-native simulations. The company serves large enterprises seeking to build a more capable, AI-ready workforce through consistent evaluation methodologies.
AI & Machine LearningEnterprise SoftwareHR Tech
Karat provides financial products and credit solutions for creators and entrepreneurs. The platform serves individual creators, talent agencies, and creator-focused businesses with tools to manage finances and access credit.
Creator EconomyFintechLos Angeles, US
Ledger is a brokerage and advisory firm specializing in casualty insurance-linked securities (ILS), connecting insurers and reinsurers with institutional capital providers. The firm structures transactions to provide off-balance sheet capital solutions for insurance and risk markets.
FintechInsurTechUnited States, US
Samir Shah(Founder/CEO)in
Mercura builds software to improve productivity and operations at companies in construction and manufacturing. The company serves enterprises in traditional industries that form the backbone of the economy.
AI & Machine LearningConstruction TechEnterprise SoftwareSaaSSales Tech
Lukas Bock(Business Development)inStefan Zheng(Product Development)inSean Sdahl(Technical Development)
Scope AR develops augmented reality software and solutions for enterprise customers in aerospace, aviation, manufacturing, medical device, semiconductor, and CPG industries to help workers visualize and solve complex tasks.
Advanced ManufacturingAI & Machine LearningConsumerDeep TechEnterprise SoftwareHardwareSaaSSan Francisco, US
SigNoz provides observability and monitoring tools that help DevOps engineers and developers reduce noise and extract actionable signals from their systems. The platform serves engineering teams working with microservices and distributed systems.
Cloud ComputingData & InfrastructureDeveloper ToolsEnterprise SoftwareSan Francisco, US
Pranay Prateek(Co-founder & CEO)inAnkit Nayan(Co-Founder & CTO)in
Tapcart is a mobile commerce platform for Shopify brands that helps merchants build custom mobile apps to improve customer experience and drive sales. The platform enables ecommerce companies to create mobile shopping experiences that strengthen brand-customer relationships.
AI & Machine LearningDirect to ConsumerE-commerceRetail TechSaaS
Eric Netsch(Founder & CEO)Sina Mobasser(Co-founder)
Tapcart is a mobile commerce platform that helps Shopify brands build custom shopping apps to strengthen customer relationships and increase sales. The platform serves fast-growing ecommerce merchants seeking to deliver a differentiated mobile shopping experience.
AI & Machine LearningDirect to ConsumerE-commerceSaaS
Eric Netsch(Founder & CEO)Sina Mobasser(Co-founder)
TestBox is a buying and selling operating system designed to optimize the software purchasing experience for customers. The platform helps buyers make confident purchasing decisions and enables sellers to close larger deals through improved customer experience design.
AI & Machine LearningDeveloper ToolsEnterprise SoftwareMarketing TechSaaSSales Tech
Finder for Teams is an AI-powered analytics platform that automatically discovers patterns in data warehouse systems and identifies business outcomes that impact KPIs. It integrates with data platforms like Snowflake and BigQuery to help analytics teams find and validate actionable insights with estimated financial impact before implementation.
AI & Machine LearningData & InfrastructureDeveloper ToolsEnterprise Software
Frequently asked questions
- What stage does SignalFire invest at?
- SignalFire invests at the Seed, Series A, Series B, Series C stages.
- What sectors does SignalFire focus on?
- SignalFire focuses on AI & Machine Learning, Sector Agnostic.
- Where is SignalFire located?
- SignalFire is headquartered in San Francisco, US.
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