Deerfield Management Company
Venture capitalNew York · Growth–Late Stage · 90 people tracked
Also known as DEERFIELD MANAGEMENT COMPANY, L.P.
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Investment thesis
Deerfield advances healthcare through the combination of investment, information, and philanthropy. It provides flexible funding models to companies spanning the healthcare ecosystem and applies AI, data, and market research to drive healthcare technology and innovation. The firm builds companies independently and alongside strategic partners, forming alliances with research institutions and technology companies. Its New York City-based not-for-profit foundation supports innovative healthcare initiatives, reflecting a broad approach that blends capital, information services, and charitable activity across the sector.
Source: firm website, verified Sep 15, 2026.
Team · 90 people
from the firm's website & public directoriesWhat they invest in
from 67 of 80 portfolio companiesHealthtech ×42Biotech ×35Medical Devices ×21Digital Health ×17AI & Machine Learning ×12Deep Tech ×6SaaS ×5Enterprise Software ×3
HQs:United States×62
Investments · 80 tracked
founders shown can be your intro pathBy year:2026 · 32025 · 52024 · 52023 · 22022 · 132021 · 52020 · 112019 · 22018 · 32017 · 32016 · 22015 · 357 dated
Black Diamond Therapeutics develops small-molecule kinase inhibitors targeting families of oncogenic mutations across cancer types, including its lead candidate silevertinib for EGFR-mutant lung cancer and glioblastoma.
Elizabeth Buck(Chief Scientific Officer)inBrent Hatzis-Schoch(Chief Operating Officer and General Counsel)inSergey Yurasov(Chief Medical Officer)inMelanie Morrison(Chief Development Officer)
Co-investorsLAVLilly Asia VenturesNew Enterprise Associates (NEA)Nextech InvestNSG VenturesRA Capital+3 more
Cabaletta Bio is a clinical-stage biotechnology company developing engineered T cell therapies for patients with autoimmune diseases.
BiotechHealthtechRadnor, US
Steven Nichtberger(Executive Officer, Director)inSteven Nichtberger, MD(Founder)inDan Geffken(Executive Officer)inAnup Marda(Chief Financial Officer)inMark Simon(Director)
BoardBrian Daniels(Director)in
Co-investors5AM VenturesBain Capital Life Sciences
Edgewise Therapeutics discovers and develops small molecule medicines targeting muscle proteins to treat neuromuscular and cardiac diseases, including sevasemten for muscular dystrophies and EDG-7500 for cardiomyopathy, leveraging a proprietary drug discovery platform based on muscle physiology and high-throughput functional assays.
BiotechDigital HealthBoulder, US
Kevin Koch(Executive Officer, Director)inAlan Russell(Director)inBadreddin Edris(Director and Co-Founder)inKenneth Harrison(Director)
BoardPeter Thompson(Director)inJonathan Root(Director)in
Co-investorsBoulder VenturesForesite CapitalOrbiMedUS Venture PartnersNovo Holdings
Editas Medicine develops gene editing medicines using CRISPR/Cas9 and CRISPR/Cas12a technology to treat serious diseases including blood disorders, cardiovascular conditions, and cancer.
BiotechDeep TechMedical DevicesCambridge, US
Feng Zhang(Scientific Founder, Core Member, Broad Institute of MIT and Harvard)inGeorge Church(Scientific Founder, Professor of Genetics, Harvard University and MIT)inKeith Joung(Scientific Founder, Professor of Pathology, Harvard Medical School)inDavid Liu(Scientific Founder, Professor of Chemistry and Chemical Biology, Harvard University)inKatrine Bosley(Executive Officer, Director)inVic Myer(Executive Officer)in
Co-investorsEcoR1 CapitalSofinnova VenturesFlagship VenturesPolaris Partners
Foghorn Therapeutics is a clinical-stage biotech developing chromatin-targeted cancer drugs via its Gene Traffic Control platform, including a candidate co-developed with Eli Lilly.
Adrian Gottschalk(President and Chief Executive Officer)
Co-investorsFlagship PioneeringBiotechnology Value Fund
GeneDx provides advanced genetic testing and clinical interpretation services to help clinicians diagnose rare and inherited genetic disorders, with AI-driven genomic intelligence that supports patient care decisions and accelerates research and drug discovery.
AI & Machine LearningBiotechDigital HealthHealthtech
Katherine Stueland(CEO)in
Co-investorsOak HC/FT
Kiniksa is a global biopharmaceutical company that discovers and develops novel therapies for patients with unmet medical needs, with a focus on cardiovascular diseases and related conditions.
BiotechMedical DevicesHamilton
THOMAS W BEETHAM(Executive Officer)inSanj K. Patel(Chief Executive Officer and Chairman of the Board)
BoardSTEPHEN R BIGGAR(Director)FELIX J BAKER(Director)G. BRADLY COLE(Director)RICHARD S LEVY(Director)
Co-investorsSofinnova VenturesSofinnova Venture Partners
Pacific Biosciences develops long-read DNA and RNA sequencing platforms and kits for genomics research, including whole genome, targeted, epigenetic, and RNA sequencing applications.
BiotechDeep TechMedical DevicesMenlo Park, US
Christian O. Henry(Executive Officer, Director)inJeff Eidel(Executive Officer)inSusan G. Kim(Executive Officer)inMark Van Oene(Executive Officer)
BoardWilliam W. Ericson(Director)Hannah A. Valantine(Director)
Co-investorsDag VenturesKleiner PerkinsMaverick CapitalMohr Davidow VenturesThe Blackstone Group
SCYNEXIS develops fungerp-based antifungal therapies, including SCY-247, for treating and preventing severe, progressive, and often fatal fungal diseases and antimicrobial-resistant infections.
BiotechDurham, US
Yves J. Ribeill(Executive Officer, Director)inCharles F. Osborne, Jr.(Executive Officer)Brian Schwab(Executive Officer)inDavid Angulo(Chief Executive Officer, President and Director)in
BoardLaurent Arthaud(Director)Mounia Chaoui(Director)
Co-investorsDecheng CapitalForesite CapitalRA Capital
Xilio Therapeutics is a clinical-stage biotechnology company developing masked immuno-oncology therapies that use protein engineering to remain inactive until activated by tumor-specific proteases within the tumor microenvironment.
BiotechHealthtechWaltham, US
René Russo(Executive Officer, Director)inJoseph Farmer(Executive Officer)Timothy Clackson(Executive Officer)Christopher Frankenfield(Chief Financial and Operating Officer)inKatarina Luptakova(Chief Medical Officer)inPaul Clancy(Director)
Co-investorsBain Capital Life SciencesBay City CapitalF-Prime CapitalM VenturesMRL Ventures FundRA Capital+9 more
MMI develops miniaturized robotic surgical instruments and platforms to enable surgeons to perform complex microsurgery and supermicrosurgery on delicate anatomical structures with greater precision.
HealthtechMedical DevicesRoboticsJacksonville, US
Mark Toland(Executive Officer, Director)inAndrew Cleeland(Director)Justin Lynch(Director)inTheresa Jean Cameron(Director)Caleb Moore(Executive Officer)Augusto Vianna Castello(Director)
Board seatAndrew ElBardissi· per SEC Form D
Co-investorsAndera PartnersBioStar CapitalFidelity InvestmentsRA CapitalCorewell Health VenturesFountain Healthcare Partners
NXT Biomedical is a medical device incubator that develops and spins out startups building clinical medical technologies aimed at addressing unmet needs and reducing healthcare costs.
BiotechHealthtechMedical DevicesIrvine, US
Stanton Rowe(CEO)inDon Bobo(Director)
BoardKadhiresan V Kadir(Director)Steven Hochberg(Director)Andrew Cleeland(Director)
Board seatAndrew ElBardissi· per SEC Form D
Alo Solutions provides capital investment and practice transition support services for independent physicians seeking to expand their practices, plan for succession, or transition their patient panels.
Digital HealthEnterprise SoftwareFintechHealthtechSaaSRaleigh, US
Matt Eirich(CEO)inAngie Cain(Chief Administrative Officer)inLynn Gordon(Chief Legal & Compliance Officer)in
Pleno develops a genomic testing instrument platform designed to make multiomics testing faster, lower-cost, and higher-plex than existing methods like NGS, PCR, and microarrays.
BiotechHardwareHealthtech
Co-investorsForesite CapitalMedical Excellence Capital
SpectraWAVE develops optical and computational imaging technologies to diagnose and guide treatment decisions for patients with coronary artery disease and cardiovascular disease.
AI & Machine LearningDeep TechHealthtechMedical DevicesBedford, US
Eman Namati(President & CEO)inGuillermo Tearney(Founder; Professor of Pathology, Massachusetts General Hospital)Gregg Stone(Founder; Professor of Medicine, Mount Sinai Heart Health System)James Muller(Founder; Cardiologist, Brigham and Women's Hospital)inJeffrey O'Donnell(Founder; Managing General Partner, Runway Healthcare)Vivek Walimbe(Chief Operating Officer)in
Co-investorsLumira VenturesS3 VenturesSV Health InvestorsJohnson & Johnson Innovation – JJDC
HealthtechCarlsbad, US
Christoph Scharf(Director)inRandy Werneth(Executive Officer, Director)Graydon Beatty(Executive Officer)inVince Burgess(Director)inJohn Dahldorf(Executive Officer)
BoardAditya Puri(Director)
Board seatAndrew ElBardissi· per SEC Form D
Co-investorsAdvent Life SciencesOrbiMedFormation GroupGE VenturesIndex Ventures
Adela develops blood-based tests for cancer detection using epigenetics and liquid biopsy technology, aimed at helping patients and clinicians detect and act on cancer earlier.
BiotechDigital HealthHealthtechMedical DevicesFoster City, US
Daniel Diniz De Carvalho(Executive Officer, Promoter)Scott Bratman(Executive Officer, Director)inAnne-Renee Hartman(Founder)inAlan Williams(Executive Officer)inLisa Alderson(Executive Officer, Director)inPriscilla Huang(Executive Officer)in
Board seatAndrew ElBardissi· per SEC Form D
Co-investorsDecheng CapitalF-Prime CapitalOrbiMedMenlo Ventures
Appello Pharma is a biopharmaceutical company focused on drug discovery and development for neurological and metabolic diseases.
BiotechDigital HealthHealthtechMedical DevicesNashville, US
Dr. Laden(Co-founder)Christopher Rand(Executive Officer)Vaughn Bryson(Director)Jeff P. Conn(Director)
BoardWilliam Slattery(Director)Howie Furst(Director)in
Board seatHoward Furst· per SEC Form D · $13.5M raise · filed Jan 2022
Co-investorsMountain Group CapitalRelevance Ventures
BiotechSan Francisco, US
Matthew Patterson(Executive Officer, Director)in
BoardJonathan Silverstein(Director)inSteve Squinto(Director)inKush Parmar(Director)inThomas Woiwode(Director)
Board seatJonathan Leff· per SEC Form D · filed Sep 2015
Co-investorsAsset Management CompanyRA CapitalvenBio Partners5AM VenturesOrbiMedVenrock
Aurion Biotech develops regenerative cell therapies for ophthalmology, focused on treating blindness and vision loss from corneal endothelial disease.
BiotechHealthtechMedical DevicesSeattle, US
DAVID ROSTOV(Executive Officer)inGREG KUNST(Executive Officer, Director)PATRICK LALLY(Director)JEANNETTE BANKES(Director)CHRISTINE MCCAULEY(Director)ARNAUD LACOSTE(Executive Officer)
Board seatAndrew ElBardissi· per SEC Form D
Co-investorsVisionary VenturesFlying L Partners
Axon Therapies develops the SAVM procedure, an implant-free catheter-based ablation therapy that targets the right greater splanchnic nerve to reduce overactive sympathetic nerve activity in patients with heart failure with preserved ejection fraction (HFpEF).
HealthtechMedical DevicesNew York, US
Howard R. Levin(Executive Officer, Director)Mark Gelfand(Executive Officer)
BoardPaul LaViolette(Director)in
Board seatAndrew ElBardissi· per SEC Form D · $15M raise · filed Feb 2019
Co-investorsEarlybird Venture CapitalSV Health Investors
Dracen Pharmaceuticals is a private drug developer working at the intersection of cancer metabolism and immuno-oncology, developing glutamine antagonists that inhibit tumor glutamine metabolism and remodel the tumor microenvironment.
BiotechHealthtechBaltimore, US
Robert Wild(Co-founder & Chief Scientific Officer)Thomas M. Estok(Chief Executive Officer, President and Treasurer)Drew Pardoll, M.D., Ph.D.(Director)
BoardRobert Jackson(Director)
Board seatJonathan Leff· per SEC Form D · $40.5M raise · filed Jan 2018
Co-investorsBiotech Investments S.R.OOUP (Osage University Partners)
Jewel is a wearable patch cardioverter defibrillator designed to provide continuous protection from sudden cardiac arrest, using machine learning to minimize false alarms while requiring no daily maintenance for up to a week.
AI & Machine LearningHealthtechMedical DevicesSan Francisco, US
Uday N. Kumar(Executive Officer, Director)in
BoardRussell Hirsch(Director)Neil Exter(Director)inKrishna Yeshwant(Director)inWilliam H. Kucheman(Director)
Board seatAndrew ElBardissi· per SEC Form D · $145.6M raise · filed Mar 2020
Co-investorsThird Rock VenturesGV (Google Ventures)
Clinical-stage biotech developing next-generation polyene antifungals for life-threatening invasive fungal infections.
BiotechNew York, US
Kieren Marr(Executive Officer, Director)
BoardJim Flynn(Director)Martin Heidecker(Director)in
Board seatJonathan Leff· per SEC Form D
Co-investorsAMR Action FundIllinois Ventures
Incardatherapeutics develops drug therapies for treating atrial fibrillation using synergistic combinations of anti-arrhythmic agents, with delivery platforms designed for both hospital and at-home settings.
BiotechDigital HealthMedical DevicesBrisbane, US
Carlos A. Schuler(Executive Officer, Director)inJohn S. Patton(Executive Officer, Director)inRangachari Narasimhan(Executive Officer, Director)Grace Colon(Executive Officer, Director)inMiller Samantha(Executive Officer)
BoardMcCarthy Reenie(Director)
Board seatAndrew ElBardissi· per SEC Form D
Co-investorsAsset Management CompanyHealthCapSofinnova Ventures
BiotechNew York, US
Nader Halim(Executive Officer, Director)Althea Stillman(Executive Officer, Director)
BoardDavid Greenwald(Director)in
Board seatJonathan Leff· per SEC Form D
Co-investorsBioAdvance
NeoChord develops a medical device system for beating heart mitral valve repair in patients with mitral valve regurgitation.
Advanced ManufacturingHealthtechMedical DevicesMaple Grove, US
Todd Berg(Executive Officer, Director)inDavid H. Chung(Executive Officer, Director)inRon Nelson(Executive Officer)in
BoardCasey Tansey(Director)Mudit K. Jain(Director)
Board seatAndrew ElBardissi· per SEC Form D · $6M raise · filed Nov 2022
Co-investorsTreo Ventures, LlcUS Venture Partners
Reprieve Cardiovascular develops a decongestion management system that uses real-time patient data to guide and personalize diuretic therapy for fluid removal in heart failure patients.
Digital HealthHealthtechMedical DevicesMilford, US
Tony Fields(Executive Officer)Adam Bartnik(Executive Officer)inMark Pacyna(Executive Officer, Director)inJim Dillon(Executive Officer, Director)Hanson S. Gifford III(Director)Gregory W Mann(Executive Officer)
Board seatAndrew ElBardissi· per SEC Form D
Co-investorsArboretum VenturesLightstone VenturesRex Health VenturesGenesis Venture CapitalSante Ventures
Neomorph develops a molecular glue discovery platform to identify small-molecule medicines that degrade disease-causing proteins through targeted protein degradation.
AI & Machine LearningBiotechDeep TechSan Diego, US
Co-investorsLongwood Fund
Actio is a precision medicine company developing therapeutics by leveraging genetic insights to treat rare diseases and common conditions at their molecular root.
AI & Machine LearningBiotech
Co-investorsDroia VenturesCanaan Partners
Ascertain provides an agentic AI platform that automates healthcare administrative work such as prior authorizations, referrals, eligibility checks, and care coordination by integrating with existing systems and embedding human review.
AI & Machine LearningDigital HealthHealthtechNew York, US
Mark Michalski(Executive Officer, Director)inMarc Berger(Executive Officer)Gregg Fergus(Executive Officer, Director)Laurence Kraemer(Executive Officer)
BoardMoses Adubi(Director)Konstantine Costalas(Director)
Co-investorsAegis Ventures
Cohere Health provides a platform aimed at aligning the interests of patients, physicians, and health plans to support care decisions and improve member outcomes.
AI & Machine LearningDigital HealthEnterprise SoftwareHealthtechSaaSBoston, US
Siva Namasivayam(Executive Officer, Director)inRobert Shepardson(Executive Officer)inKristen Carucci(Executive Officer)inDuncan Reese(Executive Officer)
BoardDavid Barrett(Director)Amir Debourou(Director)
Co-investorsCota CapitalFlare Capital PartnersLongitude CapitalDefine VenturesFlare Capital StrategiesPolaris Partners+1 more
ConcertoCare provides coordinated in-home and center-based medical, behavioral, and social care for seniors and adults with complex care needs who have Medicare, Medicare Advantage, or Medicare+Medicaid coverage.
Digital HealthHealthtechLongevity
Co-investorsAtento CapitalObvious VenturesSteelSky VenturesAddeparArboretum VenturesVast Ventures+1 more
Cortica provides in-home, in-clinic, and telehealth neurological therapies for children with autism and developmental differences, integrating neurological, biomedical, behavioral, speech-language, and sensorimotor treatments.
Digital HealthHealthtechMedical DevicesSan Diego, US
Dr. Suzanne Goh(Founder)Neil Hattangadi(Executive Officer, Director)inBriana Elvaiah(Executive Officer)in
BoardRyan Drant(Director)inStephen Anastos(Director)Justin Brock(Director)in
Co-investors.406 VenturesAIFAPERTURE Venture PartnersCVS Health VenturesEcho Health VenturesLongitude Capital+5 more
cystetic Medicines is a drug development company creating an inhaled dry-powder therapy based on an FDA-approved antifungal compound to treat cystic fibrosis, targeting the roughly 10% of patients not helped by existing modulators.
BiotechHealthtechMedical DevicesChampaign, US
MARTIN BURKE, MD., PH.D.(Director)Dr. Martin D. Burke(Co-founder)Dr. Michael J. Welsh(Co-founder)Dr. Jeffry Weers(Chief Technology Officer)PETER W STEELMAN(Director)inJONATHAN RAMOS(Director)
Co-investorsIllinois Ventures
Deerfield Catalyst is a medtech incubator that develops medical technology solutions aimed at improving patient outcomes and care delivery.
HealthtechMedical Devices
Howard Levin(CEO & CMO)inMark Gelfand(Chief Technology Officer)inZoar Engelman(Chief Science Officer)inAdam Rosenwach(Chief Business Officer)inMaybelle Jordan(Chief Strategy Officer)in
San Diego protein-sequencing company behind the ProteoCode platform; ceased operations in late 2025.
Co-investorsARCH Venture PartnersDecheng CapitalAlexandriaGV (Google Ventures)Nan Fung Life SciencesNorthpond Ventures
Excelsior Sciences develops automated chemistry technology for small-molecule discovery and manufacturing, targeting pharmaceutical and materials development.
AI & Machine LearningBiotechDeep Tech
Marty BurkeBartosz GrzybowskiMichael Foley(CEO)inJana Jensen(COO)in
Co-investorsKhosla VenturesSofinnova PartnersCornucopian Capital ManagementIllinois Ventures
Frontier is a drug discovery company developing small-molecule covalent drugs aimed at previously undruggable protein targets across the proteome.
AI & Machine LearningBiotechSouth San Francisco, US
Chris Varma, Ph.D.(Executive Officer, Director)Chris Varma(Co-founder, Chairman and CEO)inJim Winkler(Executive Officer)Johannes Hermann, Ph.D.(Executive Officer)Kevin Webster(Executive Officer)inGregory Chow(Executive Officer)
Co-investorsBerkeley CatalystDCVC (Data Collective)Droia VenturesMPM BioImpactRA CapitalDCVC Bio
Hallux Inc. develops Hallux Subungual Gel (HSG), a physician-administered terbinafine treatment applied directly to the nail bed to treat onychomycosis (fungal nail infection).
BiotechHealthtechMedical DevicesLaguna Hills, US
Hendrik Arend Kroon(Executive Officer)Mark Taylor(Executive Officer, Director)inJay Birnbaum(Executive Officer, Director)
BoardPeter Steelman(Director)inZheng Su(Director)Bryan Sendrowski(Director)
Clinical-stage genetic medicines company using human-derived AAV vectors and nuclease-free gene editing for rare diseases.
BiotechBedford, US
Siyamak Rasty(Executive Officer)Albert Seymour(Executive Officer)
BoardSteven Gillis(Director)Arthur Tzianabos(Executive Officer, Director)Kush Parmar(Director)inRichard Gregory(Director)
Co-investors5AM VenturesARCH Venture PartnersOUP (Osage University Partners)AlexandriaHBM Healthcare InvestmentsMaverick Ventures+4 more
Humanity offers an enterprise employee wellness platform that uses biological age monitoring to help teams improve health and productivity.
Digital HealthHealthtechHR TechLongevityWellness & Fitness
Peter Ward(Founder)in
Co-investorsOne Way VenturesScientia VenturesAndreessen HorowitzJump CryptoJumpstart NovaPantera Capital+1 more
Humanity provides AI-powered employee scheduling and shift-planning software for frontline and enterprise workforces, automating schedule building, demand forecasting, and labor-cost control.
Future of WorkHR TechSaaSBoston, US
Peter Ward(Executive Officer, Director)inMichael Geer(Director)
Co-investorsPoint NineSaaS CapitalJumpstart Nova
Jaguar Gene Therapy develops gene therapy treatments for severe genetic diseases, focusing on AAV-based platform therapies designed to deliver one-time, long-lasting treatments.
BiotechHealthtechMedical Devices
Co-investorsAIFARCH Venture PartnersJDRF T1D FundGoldman SachsSamsung Ventures
Lark provides AI-powered testing infrastructure for engineering teams that can test UIs, APIs, SDKs, and async workflows through natural language tests.
AI & Machine LearningDeveloper ToolsEnterprise SoftwareSan Francisco, US
Vijit Dhingra(Founder)inJack Brown(Founder)in
Co-investorsY CombinatorBridge BankFranklin TempletonKing River CapitalOlive Tree CapitalSteelSky Ventures+1 more
Lark develops AI agents that automate manual workflows for wholesale distributors, integrating with their existing ERP systems and learning from each distributor's historical data and team decisions.
Advanced ManufacturingAI & Machine LearningSan Francisco, US
Jason Wang(Founder/CEO)inMichael Wang(Co-Founder)in
Co-investorsY CombinatorFranklin TempletonKing River Capital
Lumos Pharma is a clinical-stage biopharmaceutical company developing therapies for rare diseases, with a lead candidate targeting Pediatric Growth Hormone Deficiency.
BiotechHealthtechAustin, US
Richard John Hawkins(Executive Officer, Director)John C. McKew(President and Chief Scientific Officer)inPisit "Duke" Pitukcheewanont(Chief Medical Officer)inLori Lawley(Chief Financial Officer)inBrad Powers(Chief Compliance Officer and General Counsel)inCampbell Murray(Executive Chairman)in
Co-investorsNew Enterprise Associates (NEA)Clarus VenturesSante Health VenturesSante VenturesWellcome Trust
myLaurel provides in-home medical care aimed at improving access for high-risk patients, working with clinicians and care teams.
Digital HealthHealthtech
Co-investorsBeresford VenturesCity LightFrist Cressey VenturesGV (Google Ventures)SteelSky VenturesWEEKEND
HealthtechBranford, US
Sofia Noori(Executive Officer, Director)Mariam Malik(Executive Officer)in
BoardLaura Veroneau(Director)Adrienne Rosenthal(Director)
Co-investors.406 VenturesOptum Ventures
Octave is a mental health practice platform that connects licensed therapists with patients seeking in-network mental health care.
Digital HealthHealthtechMental HealthSaaSSan Francisco, US
Sandeep Acharya(Founder, CEO)inDavid White(Executive Officer)in
BoardSaurabh Bhansali(Director)inEllie Wheeler(Director)Craig Cimini(Director)
Co-investorsFelicis VenturesGreycroftHealthier CapitalObvious VenturesHealth Velocity CapitalS32
Cambridge, US
Christophe Queva(Executive Officer)inTheodore Ashburn(Executive Officer, Director)Alon Lazarus(Director)Cameron Wheeler(Director)in
BoardBriggs Morrison(Director)inMitchell Finer(Executive Officer, Director)
Co-investorsAstellas Venture Management LLCCowen Healthcare InvestmentsK2 HealthVenturesMPM BioImpact
Practice Fusion provides a cloud-based electronic health record (EHR) platform with integrated medical billing services and e-prescribing for independent medical practices.
Digital HealthHealthtechSaaSSan Francisco, US
Ryan Howard(Executive Officer, Director)in
BoardMark Goines(Director)Beth Seidenberg(Director)inMichael Harden(Director)Cora Tellez(Director)
Co-investorsBand of AngelsCanvas VenturesLongitude CapitalArtis VenturesFelicis VenturesFounders Fund+6 more
Brooklyn, US
Marah Lidey(Executive Officer, Director)Naomi Hirabayashi(Executive Officer, Director)
BoardVictoria Song(Director)
Co-investorsComcast VenturesLaunchCapitalFidelity InvestmentsOaktreeSumitomo Corporation
ShineMed pursues a step-by-step commercialization approach to fusion energy, aiming to prove market value at each stage while generating revenue toward the goal of clean, abundant fusion power.
CleantechDeep TechEnergyHealthtechJanesville, US
Gregory Richard Piefer(Executive Officer, Director)Katrina Pitas(Executive Officer)Darin Janecek(Executive Officer)Anton Asmuth(Executive Officer, Director)James Costedio(Executive Officer)David A. Weissburg(Executive Officer, Director, Promoter)in
Co-investorsVenture ManagementWisconsin Investment PartnersBaillie GiffordKoch Disruptive Technologies
Somatus provides value-based, integrated kidney care and a congestive heart failure management solution for patients, providers, and health plan partners.
Digital HealthHealthtechMclean, US
Ikenna Okezie(Executive Officer, Director)inAlexander Houlday(Executive Officer)inStacey Queen-Pyndell(Executive Officer)Larry Renfro(Interim President & CEO)
BoardAnna Haghgooie(Director)Anthony Welters(Director)
Co-investorsFlare Capital PartnersOptum VenturesHealthQuest CapitalBlue Venture FundsDefy PartnersLongitude Capital+7 more
Soon is a portfolio management platform that automates buying and selling of assets across multiple exchanges using strategies like dollar-cost averaging and tax-loss harvesting.
Crypto & Web3FintechSalt Lake City, US
Michael Shattuck(Founder)in
Co-investorsY CombinatorFidelity InvestmentsOaktree
Strata Oncology develops precision oncology biomarkers and predictive diagnostic tools for cancer treatment, including treatment response scores for antibody-drug conjugates (ADCs) and an Immunotherapy Response Score for anti-PD-1/PD-L1 therapies.
AI & Machine LearningBiotechDigital HealthMedical DevicesAnn Arbor, US
Daniel Rhodes(Executive Officer, Director)Matthew Martin(Executive Officer)Jeffrey Williams(Executive Officer, Director)
BoardChristopher O'Donnell(Director)inDavid Rubin(Director)inJames Pavlik(Director)in
Co-investorsArboretum VenturesPfizer Venture InvestmentsMerck Global Health Innovation FundPfizer Ventures
Synthekine is a clinical-stage biotechnology company using protein engineering platforms to develop cytokine-based immunotherapies designed to preserve therapeutic efficacy while avoiding toxicities linked to cytokine pleiotropy.
BiotechHealthtech
K. Christopher Garcia(Founder)Susan Molineaux(CEO)inMartin Oft(Chief Scientific Officer)inNaiyer Rizvi(Chief Medical Officer)inGregory(Chief Technical Officer)Geoff(Chief Business Officer)
Co-investorsSamsara BioCapitalThe Column GroupBain Capital Life SciencesCanaan PartnersRA CapitalTCG Crossover+2 more
Endologix develops endovascular medical devices for treating vascular conditions such as abdominal aortic aneurysms and peripheral arterial disease in the femoropopliteal arteries.
HardwareHealthtechMedical Devices
John Liddicoat(President and Chief Executive Officer)Graham Phillips(Chief Operating Officer)Cindy Pinto(Chief Financial Officer)Jorge O'Hara(Chief Commercial Officer)in
Co-investors415 CapitalNew Enterprise Associates (NEA)
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Aprecia PharmaceuticalsConventus OrthopaedicsHumanity Health, Inc.Iowa ApproachPerfect HealthSpringtide Child DevelopmentBitterroot BioBlade TherapeuticsEpion HealthIntus CareLiquid WireMMIPerceive BiotherapeuticsPhoenix Nuclear LabsPQ BypassRay TherapeuticsReady RespondersV-WaveVibliome Therapeutics剂泰科技 (METiS TechBio)
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Exits · 11
11 IPOs · showing 10Black Diamond Therapeutics, IncNASDAQ: BDTXCabaletta BioNASDAQ: CABAEdgewise TherapeuticsNASDAQ: EWTXEditas MedicineNASDAQ: EDITFoghorn TherapeuticsNASDAQ: FHTXGenedxNASDAQ: WGSKiniksaNASDAQ: KNSAPacific Biosciences of CaliforniaNASDAQ: PACBScynexisNASDAQ: SCYXXilio TherapeuticsNASDAQ: XLO
Portfolio news
latest coverage across their companiesEditas Medicine · za.investing.com · Sep 9, 2026
Humanity · highlandsnews.com · Sep 3, 2026

Black Diamond Therapeutics, Inc · finance.yahoo.com · Sep 2, 2026

Aurion Biotech · regmednet.com · Aug 20, 2026


Shine · outlookbusiness.com · Aug 17, 2026
Edgewise Therapeutics · themarketsdaily.com · Aug 17, 2026
Xilio Therapeutics · tickerreport.com · Aug 15, 2026
Fund performance · per public LP disclosures
as of Jun 2024| Fund | Vintage | Committed | Net IRR | TVPI | DPI |
|---|---|---|---|---|---|
| Deerfield Private Design Fund IVLPs: Florida State Board of Administration, Robert Wood Johnson Foundation | 2007 | — | 7.9% | 1.45x | 0.11x |
Source: public limited-partner disclosures (CalPERS, CalSTRS). Net IRR / TVPI / DPI as reported by the limited partner; a fund's early-year IRR is an interim estimate (J-curve).
IPO stake values · per SEC filings · 7
Value of this firm's stake in each portfolio company at its IPO price, from the prospectus principal-stockholder table.
| Company | Owned | IPO price | At IPO | Stake value |
|---|---|---|---|---|
| Edgewise Therapeutics | 7.0% | $16.00 | Mar 2021 | $52.9M |
| Pacific Biosciences of California | 3.9% | $16.00 | Oct 2010 | $32.4M |
| Editas Medicine | 4.8% | $16.00 | Feb 2016 | $27.4M |
| Xilio Therapeutics | 5.7% | $16.00 | Oct 2021 | $24.2M |
| Kiniksa | 6.7% | $18.26 | Feb 2019 | $22.4M |
| Cabaletta Bio | 3.9% | $11.00 | Oct 2019 | $10.2M |
| Scynexis | 3.8% | $7.70 | Apr 2015 | $3.9M |
Source: SEC S-1 / 424B prospectus filings. Stake value = shares beneficially owned × the initial public offering price, as disclosed — a market value at IPO, not a return multiple (the firm's original cost is not disclosed).
Public market activity · per SEC filings
what is this? ⓘ59 insider ownership filings (Forms 3/4/5)
From the firm's own SEC EDGAR filings — stakes and insider roles in public companies, typically portfolio companies after an IPO. Not a portfolio list published by the firm.
Frequently asked questions
- How many investments has Deerfield Management Company made?
- Deerfield Management Company has 80 tracked investments, 11 of which have exited, including 9 dated in the last 24 months.
- What stage does Deerfield Management Company invest at?
- Deerfield Management Company invests at the Growth, Late Stage stages.
- What sectors does Deerfield Management Company focus on?
- Deerfield Management Company focuses on AI & Machine Learning, Biotech, Digital Health, Healthtech, Medical Devices.
- Where is Deerfield Management Company located?
- Deerfield Management Company is headquartered in New York, US.
- Does Deerfield Management Company lead rounds?
- Deerfield Management Company has led 9 of the 15 rounds where its role is on record.
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Co-investors · 38
GV (Google Ventures) is a venture capital firm that has invested in artificial intelligence and machine learning since its early days, building a global portfolio of more than 100 AI companies across infrastructure, life sciences, and applications.
OrbiMed is a global healthcare-focused investment firm providing financing and operational support to companies across biopharmaceuticals, medical devices, digital health, diagnostics, and healthcare services.
ARCH Venture Partners is a venture capital firm that invests in and helps build transformational companies, with a strong focus on the life sciences and biotechnology sector.
Optum Ventures is a venture capital firm that invests in entrepreneurs building companies to transform healthcare.
New Enterprise Associates (NEA) is a venture capital firm that invests in and provides long-term support to founders building new companies.
OUP (Osage University Partners) is a venture firm that invests in science-driven startups commercializing deep technology innovations emerging from university and breakthrough research.
5AM Ventures is a life science venture capital firm founded in 2002 that invests primarily in private therapeutic companies, with a focus on biopharmaceuticals, drug delivery technologies, and life science instruments.
MPM BioImpact combines 30+ years of biotech venture capital expertise with impact investing and public market experience, managing early-stage venture funds, private/public impact funds, and a public equities fund focused on transforming patient outcomes.
Foresite Capital is a healthcare-focused investment firm backing companies at the intersection of technology and biotechnology to personalize healthcare and accelerate medical innovation.
SteelSky Ventures is an AI-focused healthcare venture fund that backs companies opening new markets and advancing healthcare innovation, with an emphasis on women's health and health equity.
Canaan Partners is a venture capital firm with over 30 years of history, backing companies across technology and healthcare sectors through close, hands-on partnerships with founders.
Obvious is a venture capital firm focused on supporting founders building solutions to humanity's largest challenges across planetary health, human health, and economic health.
▶26 more co-investors
US Venture PartnersFlare Capital PartnersCity LightAndera PartnersFranklin TempletonAndreessen HorowitzDCVC (Data Collective)Oak HC/FTVast VenturesS32Northpond VenturesVivo CapitalRiverVest Venture PartnersMerck Global Health Innovation FundKing River CapitalAPERTURE Venture PartnersSequoia CapitalBain Capital VenturesTiger Global ManagementC2 InvestmentsParadigmHaun VenturesDomain AssociatesNovartis Venture FundFrazier Healthcare PartnersRoche Venture Fund
Firms observed investing alongside Deerfield Management Company, from public investor directories. Shared companies are the overlap with Deerfield Management Company's recorded portfolio.
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