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Novartis Venture Fund

Corporate VC

Basel · Pre-Seed–Late Stage · 25 people tracked

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Investment thesis

The Novartis Venture Fund backs innovative life science companies working in biotechnology and biopharmaceuticals across a range of stages, from early-stage startups to later-stage companies. It seeks to develop novel therapeutics and platforms that address unmet patient needs across the healthcare spectrum. The fund takes a hands-on approach, working closely with boards and management to deliver clinical impact. Its team, split between Basel and Cambridge, has expertise in drug development across diverse therapeutic areas and modalities. The fund manages over USD 750 million in committed capital and holds more than 40 portfolio companies across North America and Europe.

Invests inBiotechDigital HealthHealthtechMedical DevicesEuropeNorth AmericaSwitzerlandUnited States

Source: firm website, verified Aug 3, 2026.

Stage
Pre-Seed–Late Stage
Check
$5M – $25M
HQ
Basel, MA, CH
Leads rounds
Leads
Instruments
Equity
Founded
1996
AUM
$750M
Tracked investments
35

Team · 25 people

from the firm's website & public directories
Anja Koenig· Global Head of NVFin
Aaron Nelson· Managing Directorin
Florian Müllershausen· Managing Directorin
Henry Skinner· Managing Directorin

What they invest in

from 23 of 35 portfolio companies

Biotech ×21Medical Devices ×13Deep Tech ×8AI & Machine Learning ×3Digital Health ×3Healthtech ×3Cybersecurity ×1Defense Tech ×1

HQs:United States×6Switzerland×3Australia×1Colombia×1Spain×1France×1

Investments · 35 tracked

founders shown can be your intro path
Granite Biogranitebio.comin✓ verified

Granite Bio develops first-in-class therapeutic antibodies targeting inflammation, autoimmunity, and fibrosis for patients lacking effective treatment options.

BiotechMedical DevicesBasel, CH

Patrick Loustau(President and Chief Executive Officer)

HYKU Bioscienceshykubiosciences.comin✓ verified

Hyku Biosciences develops covalent medicines to improve patient outcomes by advancing the scientific boundaries of this therapeutic approach.

BiotechDeep TechMedical DevicesBurlington, US

JOHN GUSTOFSON(Director)LAURA TADVALKAR(Director)KLEEM CHAUDHARY(Executive Officer, Director, Promoter)MATTHIAS VAN WOENSEL(Director)Kleem Chaudhary, PhD(President & CEO)Ku-Lung (Ken) Hsu, PhD(Endowed Associate Professor of Chemistry)

ONL Therapeuticsonltherapeutics.com✓ verified

ONL Therapeutics is a clinical-stage biopharmaceutical company developing neuroprotective treatments for retinal diseases including retinal detachment, geographic atrophy, and glaucoma.

BiotechHealthtechMedical DevicesAnn Arbor, US

David Zacks(Executive Officer)David Esposito(Executive Officer, Director)Constance Chang(Executive Officer)Loic Couraud(Director)William Brinkerhoff(Director)Mark Hooper(Director)

RhyGaze AGrhygaze.com✓ verified

RhyGaze develops gene therapies using optogenetic proteins to restore sight in patients with vision loss caused by retinal photoreceptor dysfunction.

BiotechDigital HealthMedical DevicesBasel, CH

Botond Roska(Researcher (M.D., Ph.D.))Bence György(IOB Assistant Professor & Head of Clinical Translation)Katherine High(CEO)

Splice Biosplice.bioin𝕏✓ verified

SpliceBio develops genetic medicines using a proprietary protein splicing platform to treat diseases caused by mutations in large genes.

BiotechDeep TechDigital HealthBarcelona, ES

Dr. Frutos(Co-founder)Dr. Vila-Perelló(CEO)

ImmPACT Bio USA Inc.SEC filingmedium confidence

West Hills, US

Board seatMichal Silverberg· per SEC Form D · $5.5M raise · filed Aug 2020

Mediar Therapeuticsmediartx.comin

Mediartx develops novel therapies for patients with fibrotic diseases.

BiotechMedical DevicesBoston, US

Rahul Ballal, PhD(CEO)Paul Yaworsky, PhD(CSO)inRahul Ballal(Executive Officer, Director)Brian Hubbard(Director)Stacey Brenner(Executive Officer)David de Graaf(Director)

Board seatAnja Konig· per SEC Form D

0 2 AstronauTxastronautx.bioin
Alestaalestatherapeutics.comin
Amphistaamphista.com
Anaveonanaveon.comin

Anaveon develops engineered antibodies targeting immune system regulatory nodes to treat autoimmune diseases by selectively eliminating or reprogramming pathogenic immune cells.

BiotechBasel, CH

Thaminda(Chief Business Officer)inLaetitia Pouzol(Chief Scientific Officer)in

Aravaxaravax.com.auin

Aravax develops immunotherapies using proprietary peptides to treat food allergies, with a focus on retraining the immune system to tolerate specific foods.

BiotechHealthtechMelbourne, AU

Artios
Arvada
Atalantaatalanta.techin𝕏

Atalanta is a mathematical AI company that provides software verification and formal methods capabilities to ensure provably correct decision-making in complex systems for high-stakes missions in energy, space, and defense sectors.

AI & Machine LearningDeep TechDefense Tech

Atalantaatalantatx.com
Avernatxavernatx.comin

Averna Therapeutics develops non-viral gene delivery technology using lipid nanoparticles and engineered retrotransposons to safely insert genetic instructions into cells.

BiotechDeep TechMedical Devices

CatalYmcatalym.comin
Citryllcitryll.comin
Epi Biologicsepibiologics.comin

Epibiologics develops protein degradation medicines using protein sciences and antibody engineering capabilities.

BiotechMedical Devices

BoardMichael Kavanaugh(Founding Advisor)

Epsilogenepsilogen.comin

Epsilogen discovers and develops antibody therapeutics across multiple immunoglobulin isotypes (IgE, IgA, IgG) for cancer treatment.

Biotech

Exo Therapeuticsexo-therapeutics.comin𝕏

Exo Therapeutics is a small molecule drug discovery company developing therapeutics through its ExoSight platform, which targets exosites—unique binding pockets on enzymes—to address previously undruggable diseases in oncology, inflammation, and other therapeutic areas.

BiotechDeep TechMedical Devices

David Liu, PhD(Founder)Alan Saghatelian, PhD(Co-Founder)David LiuAlan Saghetelian

Forefore.bioin𝕏

FORE Biotherapeutics develops next-generation targeted oncology treatments, specifically plixorafenib, a novel BRAF inhibitor designed to treat patients with BRAF-altered solid tumors and other cancers.

BiotechMedical Devices

FoRx Therapeuticsforxtherapeutics.comin
Gentibiogentibio.comin𝕏

GentiBio develops engineered T-regulatory cells (Tregs) as allogeneic therapeutics for autoimmune and inflammatory diseases.

BiotechHealthtechMedical Devices

Immunitas Therapeuticsimmunitastx.comin

Immunitas discovers and develops therapeutic antibodies for cancer and autoimmune diseases, with its lead program targeting CD161 for solid tumors and hematological malignancies.

BiotechDigital HealthMedical DevicesWaltham, US

Laura Brass(Director)Amanda Wagner(Executive Officer)Kai Wucherpfennig(Director)Dan Matloff(Executive Officer)Jiaping Gu(Director)Jeffrey Goldberg(Executive Officer, Director)

LoQus23loqus23.comin

LoQus23 Therapeutics develops small molecule somatic expansion inhibitors aimed at stopping DNA instability to slow neurodegeneration.

BiotechDeep Tech

NRG Therapeuticsnrgtherapeutics.comin
Peptonepeptone.ioin

Peptone develops a product engine to design small-molecule drug candidates targeting intrinsically disordered proteins, which have been difficult to address with conventional drug discovery approaches.

AI & Machine LearningBiotechDeep Tech

Protegoprotegosolutions.ioin𝕏

Protego provides chargeback management software that automates dispute processes and tracks chargebacks in real time to help merchants identify patterns in fraudulent activity and recover revenue.

CybersecurityEnterprise SoftwareSaaSBogotá, CO

Pablo Rojas(Founder)in

Protegoprotegobio.com

Protego Bio develops first-in-class small molecule pharmacological chaperones designed to restore protein function and treat protein misfolding diseases such as cardiomyopathy and AL amyloidosis.

AI & Machine LearningBiotechDeep Tech

Salvinasip-baselarea.comin𝕏
Sidewinderbiosidewinderbio.comin

Sidewinder Bio develops next-generation bispecific antibody-drug conjugates (ADCs) designed to treat solid tumors with enhanced specificity for difficult-to-treat cancers.

BiotechMedical Devices

Tagworks Pharmaceuticalstagworkspharma.comin𝕏

Tagworks Pharmaceuticals develops a controlled drug-release technology platform using click chemistry to enable targeted activation of antibody-drug conjugates and immunomodulators in tumors.

BiotechMedical DevicesNijmegen, NL

Vivet Therapeuticsvivet-therapeutics.comin𝕏

Vivet Therapeutics is a company focused on gene and cell therapy development, presenting research at major scientific conferences.

BiotechParis, FR

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

Frequently asked questions

What stage does Novartis Venture Fund invest at?
Novartis Venture Fund invests at the Pre-Seed, Seed, Series A, Series B, Series C, Growth, Late Stage stages.
What is Novartis Venture Fund's typical check size?
Novartis Venture Fund typically writes checks of $5M – $25M.
What sectors does Novartis Venture Fund focus on?
Novartis Venture Fund focuses on Biotech, Digital Health, Healthtech, Medical Devices.
Where is Novartis Venture Fund located?
Novartis Venture Fund is headquartered in Basel, CH.
Does Novartis Venture Fund lead rounds?
Yes, Novartis Venture Fund leads investment rounds.

Co-investors · 26

BioGeneration Ventures

BioGeneration Ventures is a venture capital firm that invests in early-stage biotech companies in Europe, with a focus on healthcare innovations.

Both backed · 4
EpsilogenRhyGaze AGCatalYmCitryll
Sanofi Ventures

Sanofi Ventures is the corporate venture capital arm of Sanofi, investing in early-stage biotech and digital health companies focused on improving human health. It serves as Sanofi's entry point into the innovation ecosystem.

$5M
Pfizer Venture Investments

Pfizer Ventures is the corporate venture arm of Pfizer that invests in life science innovation across oncology, inflammation & immunology, cardiovascular, metabolic/obesity, and vaccines, as well as platform technology companies aligned with Pfizer's strategic focus areas.

Both backed · 3
$5M – $20M
Ysios Capital

Ysios Capital is a life sciences investor that finances innovative biotech companies worldwide, providing resources to develop novel therapies for indications with high unmet medical needs.

$5.4M – $21.6M
Roche Venture Fund

Roche Venture Fund is a corporate venture arm that invests in early-stage biotech and diagnostics companies across more than 10 countries, with a portfolio exceeding 30 portfolio companies. The fund is headquartered in Basel, Switzerland.

$648K – $3.2M
GV (Google Ventures)

GV (formerly Google Ventures) is a venture investment firm that backs founders across many industries, aiming to build long-term relationships and support companies across multiple stages and milestones.

$250K – $50M
Forbion

Forbion is a global venture capital firm focused on advancing biotech innovations and sustainable solutions aimed at improving human and planetary health.

Both backed · 2
RA Capital

RA Capital invests in public and private healthcare and life science companies developing pharmaceuticals, medical devices, and diagnostic tools. The firm operates as a crossover fund across multiple investment stages.

Both backed · 1
Sofinnova Partners

Sofinnova Partners is a life sciences venture capital firm investing across the value chain from seed to later stage, with a focus on healthcare and sustainability. It backs companies in biopharma, medtech, digital medicine, agriculture and industrial processes.

Both backed · 1
$540K – $27M
MPM Capital

MPM BioImpact combines 30+ years of biotech venture capital expertise with impact investing and public market experience, managing early-stage venture funds, private/public impact funds, and a public equities fund focused on transforming patient outcomes.

Both backed · 1
0 2 AstronauTx
Advent Life Sciences

Advent Life Sciences is a trans-Atlantic venture capital firm investing in early and mid-stage life sciences companies across the UK, Europe and the USA.

Both backed · 1
Amphista
Omega Funds

Omega Funds invests in venture capital and growth equity opportunities across the life sciences sector.

Both backed · 1
14 more co-investors

Lightstone Ventures3B Future Health FundBayern KapitalNew Enterprise Associates (NEA)DCVC (Data Collective)Atlas VentureEQT Life SciencesSR One Capital ManagementDeerfield Management CompanySofinnova VenturesFrazier Healthcare PartnersAndera PartnersSeventure PartnersClarus Ventures

Firms observed investing alongside Novartis Venture Fund, from public investor directories. Shared companies are the overlap with Novartis Venture Fund's recorded portfolio.

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