Mission Biocapital
Venture capitalActively deployingSan Francisco · Pre-Seed–Series A · 21 people tracked
Also known as AWESOME ENABLERS, L.L.C. · BIOINNOVATION MANAGEMENT LLC · MBC FII MANAGEMENT, LLC · MISSION BIOCAPITAL MANAGEMENT COMPANY LLC
Investment thesis
Mission BioCapital invests early-stage capital in life science startups, pairing funding with a platform that includes shared lab space to accelerate the journey from scientific discovery to medical breakthrough. The firm emphasizes collaboration, mentorship, innovation in deal structuring, and respect for founders. Its team of scientists, investors, founders, and serial entrepreneurs has a long history of launching and building early-stage life science companies. Investing out of its fifth fund, the firm aims to be a partner from a founder's first experiment through to the clinic, helping deliver scientific solutions faster and more efficiently to individuals and communities in need.
Source: firm website, verified Aug 3, 2026.
Team · 21 people
from the firm's website & public directories
What they invest in
from 52 of 63 portfolio companiesBiotech ×43Medical Devices ×29Healthtech ×19Deep Tech ×14AI & Machine Learning ×7Consumer ×4Climate Tech ×3Longevity ×3
HQs:United States×39Azerbaijan×1
Investments · 63 tracked
founders shown can be your intro pathAlector develops therapies targeting neurodegenerative diseases including Alzheimer's, frontotemporal dementia, and Parkinson's disease through protein removal, replacement, and immune cell restoration.
AI & Machine LearningBiotechHealthtechLongevityMedical DevicesSan Francisco, US
Arnon Rosenthal(Ph.D.)Carl Gordon(Director)Tillman Gerngross(Director)Terry McGuire(Director)
Caribou Biosciences is a clinical-stage biopharmaceutical company developing CRISPR genome-editing therapies, including off-the-shelf CAR-T cell therapies for hematologic malignancies and armored cell therapies using its Cas12a chRDNA platform.
BiotechMedical DevicesBerkeley, US
Jennifer Doudna(Co-founder)Rachel Haurwitz(President and Chief Executive Officer, Co-founder)Martin Jinek(Co-founder)Andrew May(Executive Officer)Rodolphe Barrangou(Director)Jenny Rooke(Director)
Arase Therapeutics develops first-in-class oncology therapeutics that target ADP-ribose Hydrolases, novel proteins in cancer stress pathways.
BiotechMedical Devices
Paul Chang(President, CEO / CSO and Lead Founder)W. Lee Kraus(Scientific Founder)Michael Taylor(Executive Chairman)
March Bioscience is a cell therapy company assembling leading scientists and drug developers to advance cell therapy treatments.
BiotechMedical DevicesHouston, US
Sarah Hein(CEO, Co-Founder)inMaksim Mamonkin(Co-Founder, Chair Scientific Advisory Board)Malcolm Brenner(Co-founder)
BoardThomas Luby(Director)inPeter Olagunju(Director)inJoseph Petrosino(Director)
Alessa Therapeutics develops a proprietary drug-delivery platform for sustained and localized release of therapies to treat early-stage prostate cancer.
BiotechHealthtechMedical DevicesSan Carlos, US
Pamela Munster(Founder, Chief Scientific Advisor and Director)Zachary Collins(Executive Officer)Cam Gallagher(Executive Officer, Director)inRichard Lim(Director)inJohn Maroney(Executive Officer, Director)Doug Crawford(Director)in
Board seatDouglas CrawfordSteve Tregay· per SEC Form D
BiotechWaltham, US
Anthony Sun(Director)Alaa Halawa(Director)Ulrik Nielsen(Director)Jason Camm(Director)Jason Coloma(Director)Christian Kanady(Director)
Board seatUlrik B. Nielsen· per SEC Form D · $40M raise · filed Apr 2026
Cambridge, US
Board seatSteve Tregay· per SEC Form D · $170.2M raise · filed Jul 2018
Mediartx develops novel therapies for patients with fibrotic diseases.
BiotechMedical DevicesBoston, US
Rahul Ballal, PhD(CEO)Paul Yaworsky, PhD(CSO)inRahul Ballal(Executive Officer, Director)Brian Hubbard(Director)Stacey Brenner(Executive Officer)David de Graaf(Director)
Board seatCassidy Blundell· per SEC Form D
Progentos develops small-molecule therapeutics to stimulate myelin regeneration in multiple sclerosis patients by activating oligodendrocyte progenitor cells.
BiotechDeep TechMedical DevicesWatertown, US
Aleks Radovic-Moreno(Director)Dmitrij Hristodorov(Director)Dan Janney(Director)Christopher Loose(Executive Officer, Director)Cassidy Blundell(Director)Sanjay Magavi(Executive Officer)
Board seatCassidy Blundell· per SEC Form D
QurAlis develops precision therapies for amyotrophic lateral sclerosis (ALS) and related neurodegenerative diseases by targeting specific disease-causing genetic drivers and molecular mechanisms.
BiotechDeep TechMedical DevicesCambridge, US
Kevin Eggan(Co-founder)Roet(Co-founder)Woolf(Co-founder)Laia Crespo-Martin(Director)Shafique Virani(Executive Officer)Johannes Fruehauf(Director)
Board seatJohannes Fruehauf· per SEC Form D
BiotechSan Francisco, US
Robert G. Blazej(Director)Robert Bell(Executive Officer, Director)Joseph Costello(Director)Michael D. Taylor(Director)
Board seatRobert BlazejMichael Taylor· per SEC Form D · $10.2M raise · filed Jun 2022
BiotechCambridge, US
Livio Valenti(Executive Officer)Kathryn Kosuda(Executive Officer, Director)Matthew Dirckx(Executive Officer)Lynda Tussey(Executive Officer)John Spiridigliozzi(Executive Officer)Weiner Tilsner(Executive Officer)
Board seatJohannes Fruehauf· per SEC Form D · $2M raise · filed Mar 2021
AI Proteins designs engineered miniproteins for drug discovery and development in the biopharmaceutical industry.
AI & Machine LearningBiotechDeep TechAndover, US
Dominique Verhelle(Director)Bill McKee(Director)Julia Novina(Executive Officer)Marc A. Cohen(Executive Officer, Director)Geoff Meyerson(Director)Elena Prokupets(Director)
Ambagon develops small molecule stabilizers of 14-3-3 protein complexes to modulate disease-related protein interactions, targeting therapeutic areas including cancer, metabolic disorders, neurodegenerative and infectious diseases.
BiotechDeep TechMedical DevicesEindhoven, US
Christian Ottmann(Executive Officer)Josh Seidenfeld(Executive Officer)Michelle Arkin(Director)Nancy Pryer(Executive Officer)Margarita Chavez(Director)Peter Dudek(Director)
Avvio Medical develops Microbubble SonoLithotripsy, a minimally invasive outpatient procedure that uses low-intensity ultrasound to break down ureteral stones without requiring general anesthesia or stents.
Deep TechHealthtechMedical DevicesSan Francisco, US
Arkuda is an independent information platform that provides analysis and reviews of online gaming platforms operating in Azerbaijan, focusing on legal compliance, security protocols, and user protection for gaming platforms like Mostbet.
ConsumerGamingBaku, AZ
BiotechRedwood City, US
William Robinson(Director)Lawrence Steinman(Director)Tito Serafini(Executive Officer, Director)Franklin Berger(Director)Brian Atwood(Director)
Bolt Threads was a manufacturer of biomaterials for personal care formulations.
BiotechNew MaterialsFoxboro, US
Jerry Fiddler(Director)Ethan Mirsky(Executive Officer)David Breslauer(Executive Officer, Director)Steven Vassallo(Director)Jim Kim(Director)Daniel Widmaier(Executive Officer, Director)
Cavalry Biosciences is a biopharmaceutical company focused on developing medicines that leverage the body's inherent regenerative and repair mechanisms, particularly in areas of age-related disease and tissue regeneration.
BiotechDeep TechLongevityMedical Devices
Jan van Deursen, PhD(Co-founder, Advisor)inNathaniel (Ned) David, PhD(Co-founder, Chairman)in
Circle Pharma develops cancer treatments using macrocycle therapies designed to reduce side effects compared to conventional therapies.
BiotechDigital HealthHealthtechMedical DevicesSouth San Francisco, US
Matthew P. Jacobson(Co-founder)David J. Earp(President & CEO)Paul Park(Executive Officer)Scott R. Lokey(Director)Douglas Crawford(Director)Walter Moos(Director)
Cambridge, US
ENEJ KUSCER, PH.D.(Executive Officer)PETER VAN VLASSELAER, PH.D.(Director)HENRIJETTE RICHTER, PH.D.(Director)BERNARDUS MACHIELSE(Director)LUCAS DE BREED(Director)DAVID DE GRAAF, PH.D.(Executive Officer, Director)
Dren Bio is a clinical-stage biopharmaceutical company developing novel antibody therapeutics designed to selectively eliminate pathogenic cells and disease-causing agents, with a pipeline targeting oncology, autoimmune diseases, immunology, and neurology.
BiotechHealthtechMedical DevicesFoster City, US
Nenad Tomasevic(Executive Officer, Director)Ivan Trifunovich(Director)John Wesley(Director)
eFFECTOR Therapeutics was a clinical-stage biopharmaceutical company.
BiotechSolana Beach, US
Stephen F. Worland, Ph.D.(Executive Officer, Director)Alana McNulty(Executive Officer)Simeon George(Director)Jonathan Root(Director)Ken Haas(Director)Laurence Lasky(Director)
Eikonizo develops small molecule therapeutics targeting neurodegenerative and cardiorenal diseases.
AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesBeverly, US
William Shaw(Executive Officer, Director)Kevin Kinsella(Director)Stacie Weninger(Director)Janice Kranz(Executive Officer, Director)
Epibiologics develops protein degradation medicines using protein sciences and antibody engineering capabilities.
BiotechMedical Devices
BoardMichael Kavanaugh(Founding Advisor)
Epiodyne develops small-molecule opioids designed to optimize therapeutic outcomes, with initial focus on safer pain relief and improved opioid use disorder treatment with reduced addiction and respiratory depression risk.
BiotechHealthtechMedical DevicesSan Francisco, US
Douglas Crawford, Ph.D.(CEO)Don Gehlert, Ph.D.(Head of Biology)Brian Shoichet(Director)
BoardDouglas Crawford(Executive Officer, Director)
Glycomine develops therapeutics for rare diseases, many of which currently lack disease-modifying treatment options.
Biotech
Steven Axon(Chief Executive Officer)Hicham Alaoui(Chief Scientific Officer)Rose Marino(Chief Medical Officer)Peter McWilliams(Chief Business Officer)Geoffrey Hird(Chief Technology Officer)
Immunos Therapeutics develops therapies for immuno-oncology and inflammatory diseases.
BiotechHealthtechMedical Devices
Invenio develops rapid on-site tissue imaging systems combined with AI to improve cancer patient care.
AI & Machine LearningBiotechDeep TechMedical Devices
Jay Trautman(President & CEO, Co-Founder)Chris Freudiger(Chief Technology Officer, Co-Founder)Christian Freudiger(Director)Doug Crawford(Director)Xiaoliang Xie(Director)
Jupiter is a biotech company that discovers and develops new medicines across multiple therapeutic areas.
BiotechChapel Hill, US
Ned Sharpless(Co-founder & CEO)Leigh Delacy(Co-founder & Partner and COO)
Mammoth Bio develops technology to read and write the code of life, operating in the biotechnology sector.
BiotechDeep TechMedical DevicesBrisbane, US
Jennifer Doudna(Founder)inTrevor Martin(Co-founder, Chief Executive Officer)Janice Chen(Co-founder, Chief Scientific Officer & President, Research)Lucas Harrington(Co-founder)inUrshit Parikh(Director)Ashley Tehranchi(Executive Officer, Director)
Myka Labs develops AI-powered sensor systems and medical devices for minimally invasive surgical repair of congenital birth defects, particularly tracheoesophageal malformations.
AI & Machine LearningDeep TechMedical DevicesSan Francisco, US
Michael Harrison(Founder and Chief Scientific Officer)Daniel Laser(CEO)Lee Swanstrom(Chief Medical Officer)
Nitrase Therapeutics develops medicines based on nitrases, a class of enzymes it discovered that are involved in a range of diseases.
Biotech
Nobell Foods produces plant-based dairy cheese made from soybean plants engineered to grow casein protein, working with Midwest farmers.
BiotechClimate TechConsumerFoodTechSan Francisco, US
Magi Richani(Founder/CEO)inKyle Vogt(Director)Chris Rivest(Director)Vijay Pande(Director)
Nocion Therapeutics develops small molecule charged sodium channel blockers (nocions) designed to silence overactive sensory nerves.
BiotechHealthtechMedical DevicesWatertown, US
VIJAY MURTHY(Director)PINI ORBACH(Director)ROSY HU(Director)MATTHEW FRANKEL(Executive Officer)PETER COUROSSI(Executive Officer)RICHARD BATYCKY(Executive Officer, Director)
PanTher develops targeted cancer therapeutics that deliver drugs directly to tumor sites at high concentrations over extended periods, aiming to improve clinical outcomes while reducing side effects.
BiotechHealthtechMedical DevicesAustin, US
Laura Indolfi(Chief Executive Officer and Co-Founder)David Ting(Director)Elazer Edelman(Director)
BoardD Mackey(Director)Daniel Wildman(Director)Darshana Zaveri(Director)
HealthtechSan Francisco, US
Leon Chen, Ph.D.(Director)Matthew F. Krummel, Ph.D.(Director)Michael Powell(Director)Carol Gallagher(Director)Joshua Resnick, M.D.(Director)Steven P. James(Executive Officer, Director, Promoter)
BiotechSouth San Francisco, US
MARTIN BABLER(Executive Officer, Director)PETER THOMPSON(Director)SRINIVAS AKKARAJU(Director)LEWIS J. SHUSTER(Director)MICHAEL DYBBS(Director)SIMEON GEORGE(Director)
Developed site-specific protein conjugation and linker technologies; acquired by Catalent Pharma Solutions in 2014.
Sensorium Therapeutics is a clinical-stage biotech company developing novel CNS therapies for anxiety, epilepsy, and cognitive dysfunction using its SensAI platform, which integrates AI, chemistry, and curated natural product data to identify therapeutic patterns from over 50 million biological relationships.
AI & Machine LearningBiotechDigital HealthMedford, US
Jerrold Rosenbaum(Director)inKevin Lalande(Director)inRichard Simon(Director)Balkrishan Gill(Director)Alexandra Glucksmann(Director)Jacob Hooker(Executive Officer, Director)in
ShapeTX develops programmable RNA medicines by combining artificial intelligence with RNA technology to address genetic causes of disease.
AI & Machine LearningBiotechDeep Tech
Josef von Rickenbach, PhD(Co-Founder)in
Symbiome develops skin microbiome-based wellness products that restore ancestral skin health through proprietary fermentation and Amazonian botanical ingredients.
ConsumerHealthtechWellness & FitnessSan Francisco, US
Adam Klausner(Executive Officer)Vicki Levine(Executive Officer, Director)Adam D'Augelli(Director)Larry Weiss(Executive Officer, Director)
Tangible Science develops contact lens solutions designed to improve comfort and durability for wearers and to provide eye care professionals with more effective treatment options.
HealthtechMedical DevicesMenlo Park, US
Chip Heath(Director)Brandon Felkins(Director)Karen Havenstrite(Director)Victor McCray(Executive Officer, Director)Richard Popp(Director)Hanson Gifford(Director)
Tune Therapeutics develops a therapeutic platform targeting the epigenome to treat complex diseases and regenerative medicine applications.
BiotechDeep TechHealthtechLongevityMedical DevicesDurham and Seattle, US
Akira Matsuno(Executive Officer)Derek Jantz(Executive Officer)Charles Gersbach(Director)John McHutchison(CEO, Chairman of the Board)Dan McHugh(Executive Officer, Director)Blythe Sather(Executive Officer)
Terrestrial develops the Tacterra microarray patch platform, a dissolvable skin-patch technology for delivering therapies including GLP-1 without injection.
BiotechHealthtechMedical Devices
Rachel Sha(CEO)
Vedere Bio develops optogenetics-based gene therapies for inherited retinal diseases (IRDs) and geographic atrophy (GA), using proprietary AAV vectors for intravitreal administration to restore vision in visually impaired patients globally.
BiotechDeep TechMedical DevicesCambridge, US
Vivace Therapeutics is an oncology-focused drug discovery and development company creating small-molecule inhibitors targeting the Hippo-YAP pathway to treat cancers including mesothelioma, meningioma, and various other tumor types.
BiotechHealthtechMedical DevicesSan Mateo, US
Edward Hu(Director)Jun Wu(Director)Jake Simson(Director)Chenguang Zhou(Director)Shuang Qiao(Executive Officer, Director)Sheng Ding(Executive Officer)
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Frequently asked questions
- What stage does Mission Biocapital invest at?
- Mission Biocapital invests at the Pre-Seed, Seed, Series A stages.
- What is Mission Biocapital's typical check size?
- Mission Biocapital typically writes checks of $500K.
- What sectors does Mission Biocapital focus on?
- Mission Biocapital focuses on Biotech, Deep Tech, Digital Health, Healthtech, Longevity, Medical Devices.
- Where is Mission Biocapital located?
- Mission Biocapital is headquartered in San Francisco, US.
- Does Mission Biocapital lead rounds?
- Mission Biocapital typically participates in rounds rather than leading them.
Images
Co-investors · 4
Polaris Partners is a venture capital firm that partners with biotech and healthcare entrepreneurs to build transformational companies.
Sanofi Ventures is the corporate venture capital arm of Sanofi, investing in early-stage biotech and digital health companies focused on improving human health. It serves as Sanofi's entry point into the innovation ecosystem.
A healthcare-focused investment firm that partners with healthcare entrepreneurs to build novel technologies and therapeutics.
EQT Life Sciences, formerly LSP, is one of Europe's largest and most experienced life sciences investors, backing companies developing therapeutics, medical devices, diagnostics and healthtech globally. It is part of EQT Group.
Firms observed investing alongside Mission Biocapital, from public investor directories. Shared companies are the overlap with Mission Biocapital's recorded portfolio.
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