APERTURE Venture Partners
Venture capitalBoston · Seed–Series C · 4 people tracked
Also known as APERTURE MANAGEMENT LLC
Investment thesis
Aperture Venture Partners focuses on healthcare investing, partnering with entrepreneurs to build innovative companies across medical devices, pharmaceuticals, healthcare IT and services, and diagnostics. The firm emphasizes its partners' deep industry knowledge and track record of helping companies reach their potential, pointing to several portfolio companies that have surpassed $1 billion valuations.
Source: firm website, verified Aug 3, 2026.
Team · 4 people
from the firm's website & public directoriesWhat they invest in
from 20 of 34 portfolio companiesHealthtech ×19Medical Devices ×15Biotech ×10Digital Health ×3Hardware ×3Deep Tech ×2SaaS ×1
HQs:United States×17
Investments · 34 tracked
founders shown can be your intro pathAclaris develops investigational monoclonal antibodies and small-molecule inhibitors targeting immune pathways for the treatment of atopic, autoimmune, and respiratory diseases.
BiotechHealthtechMedical DevicesWayne, US
Neal Walker(Executive Officer, Director)Joseph Monahan(Executive Officer)Hugh Davis(Executive Officer, Director)James Loerop(Executive Officer)Kevin Balthaser(Executive Officer)Kamil Ali-Jackson(Executive Officer)
BiotechCanton, US
Gino Santini(Director)Eran Nadav(Director)John Freund(Director)Patrick Heron(Director)Garen Bohlin(Director)David Hirsch(Director)
Shoulder Innovations develops InSet® glenoid technology for shoulder joint implants that reduce the rocking horse effect and provide mechanical stability, serving patients with severe shoulder arthritis.
HardwareHealthtechMedical DevicesNorthern California, US
Robert Ball(CEO & Executive Chairman)Matthew Ahearn(Chief Operating Officer)Geoff Pardo(Director)Jeff Points(Executive Officer)Paul Buckman(Director)Mike Carusi(Director)
Trevi Therapeutics is a clinical-stage biopharmaceutical company developing Haduvio (oral nalbuphine ER), an investigational therapy for chronic cough that targets the central and peripheral cough reflex arc.
BiotechHealthtechNew Haven, US
Edward Mathers(Director)Michael Heffernan(Director)Lisa Delfini(Executive Officer)James Cassella(Director)Dominick Colangelo(Director)Jennifer L. Good(Executive Officer, Director)
Glaukos develops surgical and pharmaceutical therapies for ophthalmic diseases including glaucoma, corneal health, and retinal disease.
BiotechHealthtechMedical DevicesWaltham, US
Jason Hong(Director)David F. Muller(Executive Officer, Director)Jeff Dykan(Director)Anthony Natale(Director)Robert Palmisano(Director)Philip J. Ferneau(Director)
BardyDx develops the Carnation Ambulatory Monitor (CAM), a lightweight cardiac patch monitor designed for extended-wear ambulatory ECG monitoring that emphasizes P-wave signal clarity.
Digital HealthHealthtechMedical Devices
Mark Querry(Executive Officer)Kevin Nelson, III(Executive Officer)Garheng Kong(Director)Rik Vandevenne(Director)Gust H. Bardy(Executive Officer, Director, Promoter)Alan Levy(Director)
Biohaven is a biopharmaceutical company focused on discovering and developing treatments in immunology, obesity, neuroscience, and oncology, including approved migraine medications.
BiotechHealthtechMedical Devices
Cardiac Dimensions develops the Carillon Mitral Contour System, an implantable device therapy for treating functional mitral regurgitation (FMR) in heart failure patients.
BiotechHealthtechMedical Devices
HealthtechEmeryville, US
Dr. Jason Hong(Director)Daniel Burnett(Director)Anthony Natale(Director)Carter Mayer(Director)Ulric Cote(Executive Officer, Director)Andrew Farquharson(Director)
Cortica provides in-home, in-clinic, and telehealth neurological therapies for children with autism and developmental differences, integrating neurological, biomedical, behavioral, speech-language, and sensorimotor treatments.
Digital HealthHealthtechMedical Devices<UNKNOWN>, US
Dr. Suzanne Goh(Founder)Neil Hattangadi(Executive Officer, Director)Briana Elvaiah(Executive Officer)Michael Wert(Director)
BoardRyan Drant(Director)Stephen Anastos(Director)
Fremont, US
Erik Engelson(Director)Skott Greenhalgh(Director)Michael Wallace(Executive Officer, Director)
Healthtech
Jerry Griffin(Director)Timothy Herbert(Executive Officer, Director)Gary Brothers(Director)Mudit Jain(Director)Marilyn Nelson(Director)Joyce Erony(Director)
HealthtechWestborough, US
Tom Patton(Director)Marc-Andre Marcotte(Director)Chris Joyce(Executive Officer)Joyce Erony(Director)Fernando Pacheco(Director)Patrick McBrayer(Executive Officer, Director)
Neuros Medical develops the Altius Direct Electrical Nerve Stimulation System, an FDA-approved implantable device for managing chronic phantom limb pain and residual limb pain in adults with lower limb loss.
BiotechHealthtechMedical DevicesAliso Viejo, US
David Veino(President, Chief Executive Officer, and Secretary)Joyce Erony(Director)William Harrington(Director)Fouad Azzam(Director)Zach Stassen(Chief Financial Officer)Marc-Andre Marcotte(Director)
NuXcel is a global medical device accelerator that founds and incubates bioelectronics and neuromodulation startups addressing large unmet clinical needs, using a lean innovation model.
Deep TechHealthtechMedical Devices
ShiraTronics is a medical device company developing an implantable device to treat chronic migraine disease.
BiotechHardwareHealthtechMedical DevicesBrooklyn Park, US
Robert Binney(Executive Officer, Director)
BoardJoyce Erony(Director)Zack Scott(Director)Brad Vale(Director)Casey Tansey(Director)Mudit Jain(Executive Officer, Director)
Menlo Park, US
Camille Samuels(Director)Duke Rohlen(Chief Executive Officer)Anthony Natale(Director)Doug Koo(Secretary)Reed Gaither(Director)Ron Kuppersmith(Director)
uLab Systems provides clear aligner and retainer solutions for dental practices, including software for treatment planning and manufacturing.
BiotechHealthtechMedical DevicesSaaS
AmirAli Talasaz(Director)Mark Foley(Director)David Thrower(Executive Officer)Tim Dumore(Director)Rita O'Connor(Director)Robert Doty(Executive Officer)
Venus Concept designs and manufactures medical aesthetic devices for dermatology and cosmetic procedures.
BiotechHealthtechMedical DevicesToronto, US
Kirk Gunhus(Executive Officer)Ross Portaro(Executive Officer)Anna Georgiadis(Executive Officer)Melissa Kang(Executive Officer)Michael Mandarello(Executive Officer)Avinash Amin(Director)
XII Medical develops neuromodulation therapies for treating obstructive sleep apnea, focusing on simplifying treatment options and improving patient outcomes.
Deep TechDigital HealthHealthtechMedical DevicesUnion City, US
Garrett Schwab(Chief Executive Officer)Shane Kreidel(Secretary and Chief Financial Officer)Aftab Kherani(Director)Zachary Eisen(Director)
BoardDuke Rohlen(Director)JD Friedland(Director)
Frequently asked questions
- What stage does APERTURE Venture Partners invest at?
- APERTURE Venture Partners invests at the Seed, Series A, Series B, Series C stages.
- What is APERTURE Venture Partners's typical check size?
- APERTURE Venture Partners typically writes checks of $1M – $5M.
- What sectors does APERTURE Venture Partners focus on?
- APERTURE Venture Partners focuses on Biotech, Digital Health, Healthtech, Medical Devices.
- Where is APERTURE Venture Partners located?
- APERTURE Venture Partners is headquartered in Boston, US.
Media · Podcasts & interviews
featuring the teamTony Natale, MD, Aperture Venture Partners, Intro: 2nd Annual PE/VC Conference
CFA Society New York · Tony Natale
Co-investors · 5
US Venture Partners (USVP) is an early-stage venture capital firm investing in information technology and healthcare companies, with four decades of investing experience.
OUP (Osage University Partners) is a venture capital firm that backs science-driven startups commercializing deep technology innovations emerging from university and breakthrough research.
Signet Healthcare Partners provides growth capital to commercial-stage healthcare companies worldwide, focusing on pharmaceutical and medical device businesses that are revenue-generating or preparing for commercial launch.
EQT Life Sciences, formerly LSP, is one of Europe's largest and most experienced life sciences investors, backing companies developing therapeutics, medical devices, diagnostics and healthtech globally. It is part of EQT Group.
Deerfield Management is a healthcare-focused investment firm that supports companies across the healthcare ecosystem through flexible funding, market intelligence, and philanthropic initiatives.
Firms observed investing alongside APERTURE Venture Partners, from public investor directories. Shared companies are the overlap with APERTURE Venture Partners's recorded portfolio.
Similar investors
Amadeus Capital Partners is a UK-based deep tech venture capital firm founded in 1997 that invests from seed to growth stages across artificial intelligence, health, and sustainability-focused technologies.
B Capital Group is a global venture capital firm that backs founders from early to late stage, with dedicated stage-based funds and a portfolio spanning technology, healthcare, and energy and resilience sectors.
Breyer Capital is a venture capital firm that backs high-impact entrepreneurs, making strategic investments guided by founder passion and its network of experienced investors.
Capricorn Venture Partners is a European investment firm managing several thematic funds across growth capital, healthcare, and cleantech, as well as a combined private/quoted investment vehicle.
DCVC (Data Collective) is a venture capital firm that backs founders building companies which apply technology to major challenges across areas such as energy, biotech, agriculture, and machine learning.