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Nocion Therapeutics

Watertown, US · Founded 2017 · Delaware corporation · 19 employees on LinkedIn · 6 known investors

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Nocion Therapeutics develops small molecule charged sodium channel blockers (nocions) designed to silence overactive sensory nerves. The company is advancing taplucainium inhalation powder, a first-in-class therapy in Phase 2b clinical development for refractory and unexplained chronic cough, with potential applications in pain, itch, and other conditions driven by neurogenic inflammation.

Founders & leadership

MF
MATTHEW FRANKELChief Medical OfficerHe brings over two decades of clinical development and medical affairs experience across major biopharmaceutical companies including Novartis (where he led the Immunology and Dermatology Medical Unit), Boehringer Ingelheim (Vice President of Clinical Development overseeing oncology, immunology, pulmonary, and CNS programs), and Chemomab (Chief Medical Officer). He holds an M.D. from UCLA, an MBA from Northwestern University's Kellogg School of Management, and a B.A. from Vassar College, and is board-certified in internal medicine.
PCPETER COUROSSI
PETER COUROSSIExecutive
RB
RICHARD BATYCKYPresident and Chief Executive Officer
JE
JAMES ELLISExecutive
MLMICHAEL LIPP
MICHAEL LIPPSenior Vice President, Pharmaceutical Development2019–2023Michael Lipp holds a B.S. in Chemical Engineering from Cornell University and a Ph.D. in Chemical Engineering and Materials Science from UC Santa Barbara, with over two decades of experience in pharmaceutical development and drug delivery across preclinical through commercial stages. He previously held senior roles in pharmaceutical development at Nocion Therapeutics, Civitas Therapeutics (acquired by Acorda), Pulmatrix, and Alkermes, and began his career as a postdoctoral fellow and staff scientist at Advanced Inhalation Research focusing on pulmonary product development.
CSCHRISTOPHER SILBER
CHRISTOPHER SILBERChief Medical Officer2020–2023
BMBRIDGET M. COLE
BRIDGET M. COLESenior Vice President & Head of Chemistry2020–2023Bridget M. Cole is an Executive Officer at Nocion Therapeutics with a background in medicinal chemistry and drug discovery; she has directed discovery research and managed chemistry, manufacturing, controls, and preclinical development activities across multiple compounds from screening through Phase 2 clinical development.
BB
Bruce Bean, PhDFounder; Professor of Neurobiology, Harvard Medical School
BL
Bruce Levy, MDFounder; Chief of Pulmonology & Critical Care, Brigham and Women's Hospital
CW
Clifford Woolf, PhD, MB, BChFounder; Professor of Neurology and Neurobiology, Harvard Medical School

Board

VM
VIJAY MURTHYBoard director
JGJULIE GRANT
JULIE GRANTBoard MemberGeneral Partner at Canaan Partners

Investors · 6

Funding

SEC filings, press & company announcements

$103.1M disclosed across 5 rounds · 2019–2025

▶$23MraisedMar 2026 · 13 investors · Pharmaceuticals
Rule 506(b)
Officers, directors & promoters on the filing
  • VIJAY MURTHYDirector
  • JULIE GRANTDirector
  • PINI ORBACHDirector
  • ROSY HUDirector
  • MATTHEW FRANKELExecutive Officer
  • PETER COUROSSIExecutive Officer
  • RICHARD BATYCKYExecutive Officer, Director
  • JAMES ELLISExecutive Officer
  • FREDDIE DEARDirector
  • MICHAEL HIGGINSDirector
Offering amount
$23M
Amount sold
$23M
First sale
Dec 2025
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$31.1MraisedMar 2024 · 13 investors · Pharmaceuticals
Rule 506(b)
Officers, directors & promoters on the filing
  • JULIE GRANTDirector
  • ROSY HUDirector
  • BERNARD SILVERMANExecutive Officer
  • RICHARD BATYCKYExecutive Officer, Director
  • FREDDIE DEARDirector
  • PINI ORBACHDirector
  • PETER COUROSSIExecutive Officer
  • MICHAEL HIGGINSDirector
  • JAMES ELLISExecutive Officer
  • VIJAY MURTHYDirector
Offering amount
$70M
Amount sold
$31.1M
First sale
Feb 2024
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$7MraisedAug 2022 · 10 investors · Pharmaceuticals
Rule 506(b)
Officers, directors & promoters on the filing
  • JULIE PAPANEK GRANTDirector
  • BRIDGET M. COLEExecutive Officer
  • JESSICA ALSTONDirector
  • MICHAEL HIGGINSDirector
  • RICHARD BATYCKYExecutive Officer, Director
  • MICHAEL LIPPExecutive Officer
  • JONATHAN GARENExecutive Officer
  • MEREDITH FISHERDirector
  • JAMES ELLISExecutive Officer
  • CHRISTOPHER SILBERExecutive Officer
Offering amount
$17M
Amount sold
$7M
First sale
Aug 2021
Incorporated
Corporation, Delaware
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$15MraisedJan 2021 · 11 investors · Pharmaceuticals
Rule 506(b)
Officers, directors & promoters on the filing
  • MICHAEL HIGGINSDirector
  • JULIE PAPANEK GRANTDirector
  • MEREDITH FISHERDirector
  • JESSICA ALSTONDirector
  • MICHAEL LIPPExecutive Officer
  • JAMES ELLISExecutive Officer
  • CHRISTOPHER SILBERExecutive Officer
  • RICHARD BATYCKYExecutive Officer, Director
  • BRIDGET M. COLEExecutive Officer
Offering amount
$25M
Amount sold
$15M
First sale
Jan 2021
Incorporated
Corporation, Delaware, 2017
Federal exemptions
06b
Full filing on SEC EDGAR ↗

Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.

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In the news

Frequently asked questions

What does Nocion Therapeutics do?
Nocion Therapeutics develops small molecule charged sodium channel blockers (nocions) designed to silence overactive sensory nerves. The company is advancing taplucainium inhalation powder, a first-in-class therapy in Phase 2b clinical development for refractory and unexplained chronic cough, with potential applications in pain, itch, and other conditions driven by neurogenic inflammation.
Who are Nocion Therapeutics's investors?
Nocion Therapeutics's investors include Canaan Partners, F-Prime Capital, Lumira Ventures, Mission Biocapital, Monograph Capital Partners, OUP (Osage University Partners).
How much funding has Nocion Therapeutics raised?
Nocion Therapeutics has disclosed $103.1M raised across 5 rounds.
Where is Nocion Therapeutics headquartered?
Nocion Therapeutics is headquartered in Watertown, US.