25Madison
Venture studioNew York · Pre-Seed–Series A · 45 people tracked
Also known as 25MADISON PROPEL FUND MANAGEMENT COMPANY, LLC · 25MADISON VENTURES MANAGEMENT COMPANY, LLC
Investment thesis
25Madison focuses on harnessing artificial intelligence to modernize legacy businesses across two main strategies. On the early-stage venture side, it incubates and invests in AI-native software and tech-enabled companies through its Studio (incubation) and Ventures (investment) arms. On the buyout side, its Propel strategy acquires and transforms lower-middle market businesses by applying AI. The platform combines company building, direct investment, and transformation buyouts under a unified applied-AI approach.
Source: firm website, verified Aug 11, 2026.
Team · 45 people
from the firm's website & public directoriesWhat they invest in
from 20 of 54 portfolio companiesHealthtech ×12AI & Machine Learning ×10Digital Health ×9SaaS ×6Enterprise Software ×4Data & Infrastructure ×2Future of Work ×2HR Tech ×2
HQs:United States×9
Investments · 54 tracked
founders shown can be your intro pathBy year:2025 · 12024 · 12022 · 12021 · 12016 · 15 dated
New York, US
Alexander Toporek(Executive Officer, Director)Daniel Teran(Director)
Board seatGrant Silow· per SEC Form D · $2.4M raise · filed Jan 2025
New York, US
Keith Cowing(Executive Officer, Director)
BoardJustine Lee(Director)
Board seatGrant Silow· per SEC Form D · filed Jun 2021
New York, US
Michael Greene(Executive Officer, Director)Miles McMullin(Executive Officer)Elie Gordis(Director)Paul Tumpowsky(Executive Officer, Director)
BoardPaul Metselaar(Director)
Board seatKirk Posmantur· per SEC Form D · $1.6M raise · filed Oct 2024
Basalt uses AI to read inbound patient referral packets and clinical documentation at intake, checking them against a facility's admission criteria and flagging risks (red/yellow/green) with citations to their source.
AI & Machine LearningDigital HealthHealthtech
Canopy develops an IoT-based wearable safety platform for healthcare organizations to protect workers from safety risks and workplace violence.
Enterprise SoftwareHealthtechIoT
Shan Sinha(Co-founder & CEO)Vinay Pulim(Co-founder & Chief Technology Officer)Hemanth Meenakshisundaram(Co-founder & Chief Scientist)
Clearpol provides AI-powered software solutions for post-acute and long-term care providers, including clinical oversight with real-time alerts, automated plan-of-correction generation, and regulatory compliance management.
AI & Machine LearningHealthtechSaaS
Hut 8 acquires, develops, and operates energy assets such as powered land, interconnects, substations, and switchyards, and builds purpose-built facilities and specialized hardware for energy-intensive technology applications.
Cloud ComputingData & InfrastructureEnergy
Ladder Health provides virtual pediatric therapy services, including speech, occupational, and physical therapy delivered by clinicians to children and families at home.
Digital HealthHealthtechBoston, US
Lynd Clinical builds and operates a fully owned network of clinical research sites focused on rural and community populations in the U.S., partnering with health systems to run trials across therapeutic areas such as metabolic, cardiovascular, neurology, and infectious disease.
AI & Machine LearningBiotechDigital Health
Marit is a free career platform for physicians and advanced practice providers (APPs) that offers crowdsourced, anonymous salary data and aggregated job listings from employers, associations, and job boards.
Digital HealthHealthtechHR Tech
Rob Anderson(Co-founder)
MIDI develops digital health solutions for patients and clinicians to improve access to and delivery of care across diverse populations.
Digital HealthHealthtechLos Altos Hills, US
Allison Gates(Director)Joanna Stober(Executive Officer, Director)Sharon Meers(Executive Officer, Director)
AI-powered sales intelligence platform analyzing body language and verbal communication from virtual meetings using NLP and non-verbal language processing.
Sift Search is a recruiting service that helps early-stage, venture-backed startups make foundational hires across engineering, product, and go-to-market roles, from founding engineers to first sales leads.
Future of WorkHR Tech
Silkline provides supply chain orchestration software for advanced manufacturers, automating procurement workflows and enabling supplier collaboration to reduce time to revenue and improve operational efficiency.
Advanced ManufacturingEnterprise SoftwareLogistics & Supply ChainSaaS
Swap Health provides telehealth nutrition care from registered dietitians who specialize in disease prevention, weight loss, and management of chronic conditions such as type 2 diabetes, hypertension, and kidney disease.
Digital HealthHealthtechWellness & Fitness
TCARE provides family caregivers with data-driven care action plans, support from TCARE specialists, and family care protection products to help them manage the emotional, physical, and financial challenges of caregiving.
Digital HealthHealthtechWellness & FitnessSt.Louis, US
Vijay Anand(Executive Officer)Mike Mings(Executive Officer)Bikram Bakshi(Director)Mohammad Ali Ahmadi(Executive Officer, Director)
Thrive Mobile provides affordable wireless plans through the Lifeline program, powered by SafetyNet Wireless, with plans starting at $0/month and integrated health resources for low-income users.
ConsumerHealthtechSaaS
Vinesight offers an AI-driven platform that detects disinformation and toxic narratives in real time, providing evidence-backed alerts to help organizations respond quickly.
AI & Machine LearningCybersecuritySaaS
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Exits · 1
IPOs and acquisitions across the tracked portfolioHut 8NASDAQ: HUT
Portfolio news
latest coverage across their companiesSilkline · originventures.com · Oct 23, 2025
Frequently asked questions
- What stage does 25Madison invest at?
- 25Madison invests at the Pre-Seed, Seed, Series A stages.
- What sectors does 25Madison focus on?
- 25Madison focuses on AI & Machine Learning, Enterprise Software, Fintech, Healthtech, Retail Tech, SaaS.
- Where is 25Madison located?
- 25Madison is headquartered in New York, US.
Images
Co-investors · 7
Founder Collective is an early-stage venture capital firm focused on seed and pre-seed investments across all sectors.
Slow Ventures is an early-stage investment firm backing curious founders at the intersection of technology and the edges of science, society, and culture, providing resources, connections, and support to build durable companies.
The General Partnership (thegp) is a venture firm that supports founders with hiring, product execution, and go-to-market help to close the execution gaps that can undermine growing companies.
23andMe Research Institute is a genetic research organization that unites a community of 11 million members to advance health discoveries and deepen understanding of human DNA through collaborative research. The institute operates a cycle where members contribute genetic data that fuels research, which produces insights and breakthroughs that flow back to members and society.
XFactor Ventures is an early-stage venture firm affiliated with the broader Flybridge community, giving portfolio founders access to a network of founders, builders, and mentors.
An investment firm focused on entrepreneurs who translate cutting-edge science and technology into solutions that advance human health.
Stage 2 Capital is a venture capital firm backed by a network of go-to-market and revenue executives, focused on helping B2B software companies scale their revenue.
Firms observed investing alongside 25Madison, from public investor directories. Shared companies are the overlap with 25Madison's recorded portfolio.
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