25Madison
Venture studioOperating companyNew York · Pre-Seed–Seed · 43 people tracked
Also known as 25MADISON PROPEL FUND MANAGEMENT COMPANY, LLC · 25MADISON VENTURES MANAGEMENT COMPANY, LLC
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Investment thesis
25Madison focuses on harnessing artificial intelligence to modernize legacy businesses across two main strategies. On the early-stage venture side, it incubates and invests in AI-native software and tech-enabled companies through its Studio (incubation) and Ventures (investment) arms. On the buyout side, its Propel strategy acquires and transforms lower-middle market businesses by applying AI. The platform combines company building, direct investment, and transformation buyouts under a unified applied-AI approach.
Source: firm website, verified Sep 29, 2026.
Team · 43 people
from the firm's website & public directoriesFounder mafia
5 people who came through 25Madison went on to found or lead other companies.
What they invest in
from 42 of 57 portfolio companiesHealthtech ×25AI & Machine Learning ×21Digital Health ×18SaaS ×17Enterprise Software ×5HR Tech ×5Data & Infrastructure ×4Advanced Manufacturing ×3
HQs:United States×26Canada×1
Who they back
founder profiles across 20 portfolio companiesFounding team size:solo founder×132 founders×33 founders×24+ founders×2
Where their founders studiedfrom 20 founders with education data
Imperial College London ×3University of Pennsylvania ×3Harvard Business School ×2Massachusetts Institute of Technology ×2
What their founders studiedfrom 19 founders with field-of-study data
Computer Science ×8Engineering ×6Business & Management ×3
Where their founders worked beforefrom 21 founders with career history
Boston Children's Hospital ×2Glispa Global Group ×2Google ×2National Guard of Cyprus ×2
1 founders hold a PhD · 4 hold an MBA (of 20 with degree data)
Investments · 57 tracked
founders shown can be your intro pathBy year:2026 · 62025 · 22024 · 12022 · 42021 · 12016 · 115 dated
Hut 8 provides secure Canadian cloud, colocation, backup, and disaster recovery services for businesses with data residency, compliance, and uptime requirements.
Cloud ComputingCrypto & Web3CybersecurityData & InfrastructureEnergy
Asher GenootinSean Glennan(Chief Financial Officer)inMichael Ho(Chief Strategy Officer & Director)inVictor Semah(Chief Legal Officer & Corporate Secretary)
Co-investorsArchetypeBitfuryCoatue ManagementFlucas VenturesOssian CapitalVisary Capital
Abstraction builds a code comprehension layer that compiles source code into a universal semantic model to generate auto-validated wikis, process graphs, system maps, and semantic PR reviews.
AI & Machine LearningDeveloper ToolsSaaS
Co-investorsInception Fund2048 VenturesAlumni VenturesAntlerBankless VenturesCosmostation+11 more
April Health provides mental healthcare integration tools and services for primary care providers, particularly serving underserved and rural communities where psychiatric specialists are scarce.
Digital HealthHealthtechMental Health
Liberty Eberly, D.O. , eMBAin
Co-investorsThe MBA Fund
Basalt is a healthcare software tool that reads incoming patient referral packets—including faxed PDFs, photographs, and scanned handwriting—extracts clinical and payer signals, and checks each referral against a facility's admission criteria, flagging findings as red, yellow, or green with links to the source document.
AI & Machine LearningDigital HealthHealthtech
Co-investorsNew Enterprise Associates (NEA)Frist Cressey Ventures
Canopy develops an IoT-based wearable safety platform for healthcare organizations to protect workers from safety risks and workplace violence.
Enterprise SoftwareHealthtechIoTPalo Alto, US
Shan Sinha(Co-founder & CEO)inVinay Pulim(Co-founder & Chief Technology Officer)inHemanth Meenakshisundaram(Co-founder & Chief Scientist)in
Co-investorsACME CapitalFounder CollectiveNextView VenturesSpero Ventures
Century Health is an AI company serving the healthcare and life sciences sector, with a stated focus on using data to support patient outcomes and its partners.
AI & Machine LearningDigital HealthHealthtech
Vish Srivastava(Founder)in
Co-investors2048 VenturesAlumni VenturesEnsemble LabsEverywhere VenturesLifeX VenturesNext Play Ventures+1 more
Clear Health provides patient billing and payment collection software for healthcare providers, helping them recover revenue from patient responsibility by delivering accurate cost estimates before service and enabling pre-visit payment options.
Data & InfrastructureDigital HealthHealthtechSaaS
Co-investorsFortySix Venture Capital
Clearpol provides AI-powered software solutions for post-acute and long-term care providers, including clinical oversight with real-time alerts, automated plan-of-correction generation, and regulatory compliance management.
AI & Machine LearningHealthtechSaaS
Arash Hosseini Jafari M.S.(Founder)in
Co-investorsIA Seed VenturesVertex VenturesRembrandt Venture Partners
Creature Studio is a design and branding firm that works across brand strategy, product design, and customer experience for its clients.
Sector Agnostic
Co-investorsActive PartnersBoost Capital PartnersTorch Capital
Croissant is a resale app and browser extension that lets consumers see the resale value of fashion and branded items they own, then sell them for cash or store credit by shipping them in.
Circular EconomyConsumerMarketplaces
John Howard(Founder)in
Co-investorsBoxGroupSidekick PartnersThird Prime
Flourish Health provides in-home mental health care for young people with serious psychiatric needs, combining clinical expertise with technology to deliver evidence-based treatment through multidisciplinary care teams.
Digital HealthHealthtechMental HealthNorth Carolina, US
Natalia Birgisson(CEO and Co-Founder)John Haskell(Co-Founder and President)Josh Gachnang(Co-Founder and Chief Technology Officer)
Co-investorsAcumen AmericaAV8 VenturesB Capital GroupCity LightF-Prime CapitalGratitude Railroad+5 more
Gratia Health offers an employee engagement platform for healthcare organizations that uses gamification, smart rewards, and real-time recognition to reinforce behaviors like shift reliability, safety, and patient experience.
HealthtechHR TechSaaS
Co-investorsCity LightHeadwater VenturesJumpstart Capital
Handspring provides virtual mental health therapy for children, teens, and young adults, with insurance coverage and rapid access to care without waitlists.
Digital HealthHealthtechMental Health
Sahil Choudhryin
Co-investorsCobalt VenturesCornucopian Capital ManagementNextView VenturesNVP CapitalRPS VenturesVamosVentures+4 more
Keragon offers a no-code platform for healthcare organizations to build HIPAA-compliant workflow automations, aimed at clinical and operations teams.
AI & Machine LearningDigital HealthHealthtechSaaS
George Eracleous(Founder)inPanos Papageorgiou(Founder)inConno Christou(Founder)inGeorge Makkoulis(Founder)
Co-investorsAfore CapitalFocal VenturesUpfront VenturesDarling VenturesFocal
Kouper builds an AI platform that automates patient-facing healthcare workflows — including appointment scheduling, insurance verification, discharge planning, and care coordination — for healthcare organizations.
AI & Machine LearningDigital HealthHealthtech
Co-investorsCVS Health VenturesGeneral Catalyst
Kyra runs influencer marketing programs for global brands, activating creators across TikTok, Instagram, and YouTube and analyzing large volumes of creator video to forecast and measure campaign outcomes.
AdTechAI & Machine LearningCreator EconomyMarketing Tech
Dev Karaca(Founder)inDevran Amaratunga Karaca(CEO & Co-Founder)Nicholas Dart(COO/CTO & Co-Founder)inStewart Rawle(Chief Commercial Officer)inSteph Fadahunsi(Chief People Officer)Ed Galvin(Chief Financial Officer)in
Co-investorsGMG VenturesTorch CapitalBonnier VenturesLionTreeBonnier CapitalMercuri.vc+6 more
Kyra is an ICHRA (Individual Coverage Health Reimbursement Arrangement) platform that handles contribution modeling, quoting, enrollment, compliance, and year-round benefits support for employers, brokers, and employees.
HealthtechHR TechInsurTech
Lucas Hearn(Founder)in
Co-investorsDorm RoomFlyover CapitalWavemaker Three-Sixty Health
Ladder Health provides digital health services focused on pediatric care and developmental screening, helping families navigate healthcare options for their children.
Digital HealthHealthtechBoston, US
Elizabeth Kidderin
Co-investorsGROOVE CAPITALHatteras Venture PartnersJumpstart CapitalMairs & Power VCNina CapitalCREATE HEALTH VENTURES
HealthtechBrentwood, US
Paul D. Gilbert(Executive Officer)inMichael S. Coggin(Executive Officer)Leif Murphy(Executive Officer)William F. Carpenter(Executive Officer, Director)inJohn P. Bumpus(Executive Officer)inDavid M. Dill(Executive Officer)in
Co-investorsApollo
Lynd Clinical operates a network of clinical research sites in underserved rural and community markets, using technology and local partnerships to expand patient access to clinical trials.
AI & Machine LearningBiotechDigital HealthHealthtech
Matt Ullum(CEO)in
M7 Health builds an AI-powered nurse and staff scheduling platform that forecasts staffing demand, auto-balances schedules, fills open shifts, and provides real-time coverage visibility for hospitals and health systems.
AI & Machine LearningDigital HealthHealthtechSaaS
Ilana Borkenstein(Co-founder)inEric Gruskin(Co-founder)in
Co-investorsFirst Round CapitalJanuary VenturesLakehouse Venture PartnersPhoenix FundThreshold VenturesBanter Capital
Marit is a free career platform for physicians and advanced practice providers (APPs) that offers crowdsourced, anonymous salary data and aggregated job listings from employers, associations, and job boards.
Digital HealthHealthtechHR Tech
Rob Anderson(Co-founder)in
Co-investorsF-Prime CapitalDefine VenturesReach Capital
MIDI develops digital health solutions for patients and clinicians to improve access to and delivery of care across diverse populations.
Digital HealthHealthtechLos Altos Hills, US
Joanna Stober(Executive Officer, Director)Sharon Meers(President & Co-founder)inJoanna Strober(Founder)inKathleen Jordan MD(Chief Medical Officer & Co-founder)inKathleen Jordan(Founder)
BoardAllison Gates(Director)in
Co-investors1843 CapitalAble PartnersAdvance Venture PartnersAvestria VenturesCity Lightf7 Ventures+19 more
Miravoice uses natural language processing to conduct automated voice interviews and surveys, capturing structured data, transcripts, and recordings.
AI & Machine LearningData & InfrastructureMarketing TechSaaSSan Francisco, US
Shreyas Tirumala(Founder)inNishant Jain(Founder)in
Co-investorsStartXUnusual Ventures
AI-powered sales intelligence platform analyzing body language and verbal communication from virtual meetings using NLP and non-verbal language processing.
Co-investorsSixth Millennium Venture Partners Management, Llc
Offload is an AI-powered platform for oversized and overweight freight operations that digitizes permits, maps route restrictions into compliant navigation, and connects dispatchers and drivers.
AI & Machine LearningLogistics & Supply ChainSaaS
Co-investorsFireroad VenturesMarket Square VenturesCERVIN VENTURES
Opsera provides a no-code, AI-powered platform for DevOps and DevSecOps automation that helps enterprises orchestrate software delivery and security across multiple tools and cloud environments.
AI & Machine LearningDeveloper ToolsEnterprise SoftwarePalo Alto, US
Kumar Chivukula(Founder)Ravi Kumar Chivukula(Executive Officer, Director)Chandra Ranganathan(Founder)
BoardRajeev Madhavan(Director)inWesley Chan(Director)inHuang Lee(Director)
Co-investorsAlumni VenturesClear VenturesFelicis VenturesHitachi VenturesProsperity7 VenturesTrinity Ventures+2 more
Paxton AI is a legal AI assistant for attorneys, law firms, and legal professionals that automates tasks such as contract review, case law research, document drafting, and analysis of medical or billing records.
AI & Machine LearningDigital HealthHealthtechLegalTechSaaS
Michael Ulin(Founder)Tanguy Chau(Founder)Tanguy Chau Michael Ulin(Founder)
Co-investorsFlori VenturesKyber Knight CapitalUnusual VenturesVoyager CapitalGaingelsIdentity.vc
Quantivly provides data liquidity and analytics tools for radiology providers, converting heterogeneous and legacy imaging data into usable insights about radiology operations.
AI & Machine LearningData & InfrastructureDigital HealthHealthtechSaaS
Robert MacDougall(Founder)in
Co-investorsBoxOne VenturesLair East LabsNina CapitalNovaCapitalOne Way VenturesService Provider Capital+1 more
Ranger provides an intelligence platform for industrial enterprises to manage procurement, engineering, and document workflows.
AI & Machine LearningDeep TechEnterprise SoftwareSaaS
Co-investorsNorthside VenturesPanache Ventures
Rebuild provides an AI-powered estimation tool designed for restoration companies to automate and accelerate the estimate generation process.
AI & Machine LearningConstruction TechInsurTechSaaS
Angelo Ferrante(Co-founder)
Co-investorsGreen Egg VenturesGutter CapitalAsymmetric Capital PartnersLightbank
Recourse automates the U.S. federal Independent Dispute Resolution (IDR) process for healthcare providers, reading claims and remittance (837/835) data to identify eligible disputes, assemble evidence, file submissions, and capture outcomes that inform future claims.
AI & Machine LearningHealthtechSaaS
Sift Search is a recruiting service that helps early-stage, venture-backed startups make foundational hires across engineering, product, and go-to-market roles, from founding engineers to first sales leads.
Future of WorkHR TechNew York, US
Silkline provides supply chain orchestration software for advanced manufacturers, automating procurement workflows and enabling supplier collaboration to reduce time to revenue and improve operational efficiency.
Advanced ManufacturingEnterprise SoftwareLogistics & Supply ChainSaaSChicago, US
Brent Shulman(Founder)in
Co-investorsBarrel VenturesMatchstick VenturesOrigin VenturesValia VenturesForward Deployed VCPlow Ventures
SNSE is an AI transformation consultancy that helps companies build strategy, integrate AI into brand, creative, UX, and operations workflows, and establish AI governance—including for regulated industries.
AI & Machine LearningEnterprise SoftwareFuture of Work
Swap Health connects patients with registered dietitians for evidence-based, personalized nutrition care and lifestyle coaching.
Digital HealthHealthtechWellness & FitnessGrove City, US
Syndicate provides infrastructure to scale the Ethereum blockchain, supporting staking and development operations on the network.
Crypto & Web3Mountain View, US
William Raphael Papper(Executive Officer, Director)Ian John Lee(Executive Officer, Director)ian //(Founder)inIan Lee(Founder)inWill Papper(Founder)
Co-investorsA.Capital Venturesa16z cryptoAndreessen HorowitzArchetypeAtelierBlueYard Capital+28 more
TCARE provides a clinical protocol combining data-driven risk algorithms and dedicated specialists to assess and reduce burnout among family caregivers.
AI & Machine LearningDigital HealthHealthtechWellness & FitnessSt.Louis, US
Mohammad Ali Ahmadi(Executive Officer, Director)Vijay Anand(Executive Officer)Mike Mings(Executive Officer)Bikram Bakshi(Director)in
Co-investorsAmerican Family VenturesClaritas CapitalConnetic VenturesSixThirty VenturesZiegler Link-age Funds
Thrive Mobile provides affordable wireless plans through the Lifeline program, powered by SafetyNet Wireless, with plans starting at $0/month and integrated health resources for low-income users.
ConsumerHealthtechSaaS
Co-investorsPrimetime PartnersCVS Health VenturesFrist Cressey VenturesWinter Street Ventures
Truehold Financial provides financing for real estate investors, including long-term loans for rental properties qualified on property cash flow and short-term loans covering purchase and renovation costs.
FintechPropTechSt. Louis, US
Azat Tulegenov(Founder)inConnie Adams(CEO)in
Co-investorsBAM VenturesClocktower VenturesGreat Wave VenturesHabitat PartnersLaunchpad CapitalSamsung Next+3 more
Vinesight offers an AI-driven platform that detects disinformation and toxic narratives in real time, providing evidence-backed alerts to help organizations respond quickly.
AI & Machine LearningCybersecuritySaaSNew York City, US
Nir Hauser(Founder)
Co-investorsAnD VenturesLightbankSeedIL Ventures
A scheduling and workforce management platform for frontline workers in manufacturing that enables flexible work arrangements and skill-based assignment matching.
Advanced ManufacturingFuture of WorkHR TechSaaS
Rahil Siddiquiin
Co-investorsIron PrairieIronspring VentureSchematic VenturesMotivate Venture Capital
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Rebuild TechnologyRuby Home ServicesSkylark Travel GroupApril HealthClearEonFlyteHealthGratiaLadderMaritNoopsRangerRanger RFXRecourse
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Exits · 1
1 IPOsHut 8NASDAQ: HUT
Portfolio news
latest coverage across their companies
Basalt Health · hitconsultant.net · Sep 24, 2026

Rebuild · thesaasnews.com · Sep 16, 2026
Ladder Health · finsmes.com · Jun 23, 2026
Century Health · trysignalbase.com · May 21, 2026
Kyra Health · kyra.health · Apr 8, 2026
Croissant · finsmes.com · Feb 25, 2026
Midi Health · finsmes.com · Feb 3, 2026
Silkline · geekwire.com · Oct 22, 2025
Frequently asked questions
- How many investments has 25Madison made?
- 25Madison has 57 tracked investments, 1 of which have exited, including 8 dated in the last 24 months.
- What stage does 25Madison invest at?
- 25Madison invests at the Pre-Seed, Seed stages.
- What sectors does 25Madison focus on?
- 25Madison focuses on AI & Machine Learning, Enterprise Software, Fintech, Healthtech, Retail Tech, SaaS.
- Where is 25Madison located?
- 25Madison is headquartered in New York, US.
- Who does 25Madison co-invest with?
- 25Madison most often shares deals with City Light, F-Prime Capital, Felicis Ventures, among 114 tracked co-investors.
Media · Podcasts & interviews
featuring the team#21 - Jaja Liao, Principal at 25Madison
Nick's Notes · Jaja Liao
Images
Co-investors · 7
Founder Collective is a seed and pre-seed stage venture capital firm that invests across sectors, describing itself as sector agnostic and anti-thematic.
23andMe is a personal genetics company that analyzes customers' saliva samples in CLIA-certified labs to deliver ancestry, trait, and health insights through direct-to-consumer DNA testing kits and subscription services.
An investment firm focused on entrepreneurs who translate cutting-edge science and technology into solutions that advance human health.
Slow Ventures is a generalist early-stage venture capital firm founded in 2011, with offices in San Francisco, Boston, and New York, investing in the earliest rounds of companies across many sectors.
The General Partnership (thegp) is a venture firm that supports founders with hiring, product execution, and go-to-market help to close the execution gaps that can undermine growing companies.
XFactor Ventures is an early-stage venture firm affiliated with the broader Flybridge community, giving portfolio founders access to a network of founders, builders, and mentors.
Stage 2 Capital is a venture firm that pairs investment with go-to-market and revenue-scaling expertise, providing portfolio companies methodologies to drive sustainable revenue growth.
Firms observed investing alongside 25Madison, from public investor directories. Shared companies are the overlap with 25Madison's recorded portfolio.
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