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HEALTHCARE ROYALTY PARTNERS

Venture debt

New York · 27 people tracked

Also known as HEALTHCARE ROYALTY MANAGEMENT, LLC

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Investment thesis

HCRx focuses on advancing biopharmaceutical innovation through creative capital solutions, principally royalty monetization and corporate financing arrangements for life sciences and biopharma companies. Since inception the firm has committed more than $7 billion across over 110 biopharma products, supporting companies that develop and commercialize approved and near-approval therapeutics. Its financing model provides non-dilutive capital tied to product revenues and royalty streams rather than traditional early-stage venture equity.

Source: firm website, verified Aug 25, 2026.

HQ
New York, US
Instruments
Debt
Founded
2016
AUM
$3.8B
Tracked investments
77

Team · 27 people

from the firm's website
Joshua C. House· Managing Director
Aaron B. Simon· Associate
Amy J. Zacharias· Senior Vice President and Controller
Hayden C.B. Futch· Associate
Jeffrey Jung· Chief Legal Officer
Lauren C. Dunn· Executive Assistant
Michele D. Romaniello· Chief of Staff
Rosa I. Mercado· Finance Clerk
Ryan P. Delaney· Associate
Stephanie A. Gilbey· Executive Assistant

What they invest in

from 38 of 77 portfolio companies

Biotech ×38Healthtech ×26Medical Devices ×7Digital Health ×5Deep Tech ×1

HQs:United States×13France×1

Investments · 77 tracked

founders shown can be your intro path

By year:2025 · 12022 · 12017 · 13 dated

Agenusagenusbio.comNASDAQ: AGEN

BiotechHealthtechMedical DevicesLexington, US

Garo Armen(Executive Officer, Director)Ozer Baysal(Executive Officer)Robert Stein(Executive Officer)Christine Klaskin(Executive Officer)Karen Valentine(Executive Officer)

BoardBrian Corvese(Director)

Co-investorsAdvent Life SciencesGrazia Equity GmbHOberland CapitalCommodore CapitalInvusLigand Pharmaceuticals+1 more

Apnimedapnimed.comin𝕏NASDAQ: APMD

Apnimed develops investigational oral pharmaceutical therapies for obstructive sleep apnea (OSA), including its lead clinical candidate AD109, a neuromuscular approach intended to treat undertreated and untreated OSA patients.

BiotechDigital HealthHealthtechCambridge, US

Lawrence G. Miller(Executive Officer, Director)Dennis Molnar(Executive Officer)Barry Wohl(Chief Business Officer)Ketan Mehta(Head of Product and Engineering, Connected Wearables)Ron Farquhar(Director)Gerald Chan(Director)

Co-investorsAlpha Wave GlobalMorningside GroupSectoral Asset Management

Aptevo TherapeuticsNASDAQ: APVOApr 2025

BiotechSeattle, US

Marvin L White(Executive Officer, Director)

Co-investorsYorkville Advisors

Atara Biotherapeuticsatarabio.comin𝕏NASDAQ: ATRA

Atara Biotherapeutics develops allogeneic T-cell immunotherapies using its proprietary EBV T-cell platform to harness the immune system for treating disease.

BiotechHealthtechMedical DevicesThousand Oaks, US

Co-investorsDag VenturesEcoR1 CapitalKleiner Perkins

Coherus Biosciencescoherus.comin𝕏NASDAQ: CHRS

Coherus Oncology develops and commercializes immuno-oncology therapies, including the approved LOQTORZI, to treat patients with cancer.

BiotechHealthtechMedical DevicesRedwood City, US

Dennis M. Lanfear(Executive Officer, Director)Denny Lanfear(Founder)inAlan C. Herman(Executive Officer)Jean-Frederic Viret, Ph.D.(Executive Officer)Peter K. Watler, Ph.D.(Executive Officer)Barbara K Finck, M.D.(Executive Officer)

Co-investorsF-Prime CapitalSofinnova VenturesVenrock

Nektar Therapeuticsnektar.comNASDAQ: NKTR

Nektar develops therapies that modulate the immune system to treat autoimmune diseases and inflammatory conditions, targeting the root causes of immune dysfunction.

BiotechHealthtechSan Francisco, US

Howard W. Robin(Executive Officer, Director)Gil M. Labrucherie(Executive Officer)Maninder Hora(Executive Officer)Stephen K. Doberstein(Executive Officer)John Nicholson(Executive Officer)Jillian B. Thomsen(Executive Officer)

Co-investorsNew Enterprise Associates (NEA)

RedHill Biopharma Ltdredhillbio.comNASDAQ: RDHL

BiotechTel Aviv

Shmuel Cabilly(Director)June Almenoff(Executive Officer)Ofer Tsimchi(Director)Rick D Scruggs(Executive Officer, Director)Nicolas Weinstein(Director)Alla Felder(Director)

Co-investorsLifeSci Venture Partners

Spero Therapeuticssperotherapeutics.cominNASDAQ: SPRO

Spero Therapeutics is a clinical-stage biopharmaceutical company developing medicines for immune-mediated diseases, led by SP001, a third-generation anti-CD40L antibody targeting IgG4-related disease.

BiotechCambridge, US

Ankit Mahadevia(Executive Officer, Director)Stephen Garbacz(Executive Officer)

BoardJean-Francois Formela(Director)inReza Halse(Director)Casper Breum(Director)Vikas Goyal(Director)

Co-investorsMRL Ventures FundOUP (Osage University Partners)RA CapitalAlphabetAtlas Venture

Acorda Therapeutics Inc
Adamas Pharmaceuticals
Adc Therapeutics
Adynovateadynovate.com

The site presents ADYNOVATE, a PEGylated recombinant antihemophilic Factor VIII injectable used to treat and control bleeding in adults and children with hemophilia A.

BiotechHealthtech

Akebia
Albireo Pharmaalbireopharma.comin

A biopharmaceutical company (Ipsen, following its acquisition of Albireo Pharma) developing and commercializing medicines in oncology, rare diseases, and neuroscience for patients with high unmet medical needs.

BiotechHealthtech

Co-investorsDecheng Capital

Ardelyxardelyx.com

Ardelyx is a biopharmaceutical company that develops first-in-class medicines for patients with unmet medical needs.

BiotechFremont, US

Michael Raab(Executive Officer, Director)Mark Kaufmann(Executive Officer)Elizabeth Grammer(Executive Officer)David Rosenbaum(Executive Officer)Jeremy Caldwell(Executive Officer)Mike Raabin

Co-investorsForesite CapitalNew Enterprise Associates (NEA)

Bexacat
Beyonttra
Bridgebiobridgebio.comin𝕏

BridgeBio develops treatments for genetic conditions and cancers using a decentralized hub-and-spoke model, where autonomous teams focus on specific diseases or drug candidates while a central hub provides clinical, regulatory, and commercial support.

BiotechHealthtech

Co-investorsAisling CapitalAmzak HealthEcoR1 CapitalFrazier Life SciencesLongwood FundSequoia Capital

Cara Therapeutics
Cetrotide
Chiasmachiasmapharma.com

BiotechNewton Centre, US

Chaime Orlev(Executive Officer)Roni Mamluk(Executive Officer, Director)

BoardScott Minick(Director)Todd T. Foley(Director)inVincent Miles(Director)Ansbert K. Gadicke(Director)in

Co-investorsSofinnova VenturesMPM BioImpact

Clearside Biomedicalclearsidebio.com

Clearside Biomedical is an intellectual property holding, investment, and commercialization company focused on its suprachoroidal space (SCS) ocular drug-delivery platform and microinjector technology.

BiotechHealthtechMedical DevicesAlpharetta, US

Charles Deignan(Executive Officer)Glenn Noronha(Executive Officer)Daniel H. White(Executive Officer, Director)Christy Shaffer(Director)Clay Thorp(Director)Mark Prausnitz(Director)

Co-investorsMountain Group CapitalSolasta VenturesHatterasHatteras Venture Partners

Copiktratm
Curis Inccuris.com

Curis is a biopharmaceutical company developing therapeutics for cancer treatment, with a pipeline targeting hematologic malignancies and other cancers through drug candidates such as its lead IRAK4 inhibitor.

BiotechHealthtech

Dyax

Biotech company focused on cancer.

Co-investorsRho Capital PartnersRho Ventures

Ebvalloebvallo-ebv.com

EBVALLO is an on-demand allogeneic T-cell immunotherapy approved to treat relapsed or refractory EBV-positive post-transplant lymphoproliferative disease (PTLD) in patients whose disease has failed rituximab with or without chemotherapy.

BiotechDigital Health

Eligardeligard.com

ELIGARD is an androgen deprivation therapy used to lower testosterone levels, which may slow the growth of prostate cancer.

BiotechHealthtech

Elobixibat
Erivedge
Esperion
Fampyra
Genfit
Heidelberg
Hemgenix
Inavir
Iqirvoiqirvo.com

IQIRVO is a prescription medicine for treating primary biliary cholangitis (PBC) in adults, used with ursodeoxycholic acid (UDCA) or alone for patients who cannot tolerate UDCA.

BiotechHealthtech

Jnj 1900 Nbtxr3
Karyopharmkaryopharm.comin𝕏Dec 2022

Karyopharm is a pharmaceutical company developing drugs based on its SINE (Selective Inhibitor of Nuclear Export) technology, with medicines targeting cancers including multiple myeloma and diffuse large B-cell lymphoma.

BiotechHealthtechNewton, US

Stuart Poulton(Executive Officer)Michael Mano(Executive Officer)Reshma Rangwala(Executive Officer)Richard Paulson(Executive Officer, Director)Stephen Mitchener(Executive Officer)Michael Mason(Executive Officer)

Co-investorsAvoro Capital AdvisorsForesite Capital

Korsuvakorsuva.com

KORSUVA is an FDA-approved prescription medicine that treats moderate-to-severe chronic kidney disease-associated pruritus (itching) in adults undergoing hemodialysis.

BiotechDigital Health

La Jolla Pharmaceutical Company
Lantheuslantheus.com

Lantheus is a radiopharmaceutical company that develops and delivers diagnostic imaging and therapeutic products used to detect, treat, and monitor disease.

BiotechHealthtechMedical Devices

Lexiva
Liquidia
Lumify
Lyricalyrica.com

Landing page for LYRICA, an FDA-approved prescription medication.

BiotechHealthtech

Modeyso
Movantik
Nanobiotixnanobiotix.comin𝕏

Nanobiotix develops physics-based nanotherapeutics for cancer treatment, applying nanotechnology to expand therapeutic options for oncology patients.

BiotechDeep TechMedical Devices

Co-investorsKarista

Opkoopko.com

OPKO Health is an integrated healthcare and pharmaceutical company that develops diagnostics and therapies for serious diseases, working with partner pharmaceutical firms across global markets.

BiotechHealthtechMedical Devices

Oracea
Orenitramorenitram.com

Orenitram is a prescription oral medication containing treprostinil, indicated to treat pulmonary arterial hypertension (PAH) by slowing disease progression and improving exercise capacity in adults.

BiotechHealthtech

Portola
Progenics Pharmaceuticals

Co-investorsSofinnova Ventures

Qs 21 Adjuvant Including Shingrix
Raptor
Regenx Biosciencesregenxbio.com

REGENXBIO is a gene therapy company developing treatments for rare and retinal diseases using its NAV Technology Platform of viral vectors, which it also licenses to other pharmaceutical and biotech companies.

BiotechHealthtechRockville, US

Kenneth T. Mills(Executive Officer, Director)

BoardJohn Daniel Kiser(Director)Allan M. Fox(Director)Benjamin Auspitz(Director)Donald J. Hayden, Jr.(Director)

Co-investorsF-Prime CapitalVenrock

Relistorrelistor.com

RELISTOR is an FDA-approved prescription medication specifically designed to treat opioid-induced constipation (OIC) by targeting the constipating effect of opioids in the gut without affecting central pain relief.

BiotechDigital Health

Relypsa

Co-investors5AM Ventures

Rezurock
Rhythm Pharmaceuticalsrhythmtx.comin𝕏Jan 2017

Rhythm Pharmaceuticals is a biopharmaceutical company that develops precision medicines and treatment options for patients with rare neuroendocrine diseases, including hyperphagia and obesity.

BiotechHealthtechBoston, US

Keith Gottesdiener(Executive Officer, Director)Bart Henderson(Mr. Henderson is the President and Treasurer of the Issuer.)

BoardEdward T. Mathers(Director)inJonathan Silverstein(Director)inNeil Exter(Director)inTodd Foley(Director)

Co-investorsForesite CapitalNew Enterprise Associates (NEA)Pfizer Venture InvestmentsOrbiMedThird Rock Ventures

Exits · 8

IPOs and acquisitions across the tracked portfolio

AgenusNASDAQ: AGENApnimedNASDAQ: APMDAptevo TherapeuticsNASDAQ: APVOAtara BiotherapeuticsNASDAQ: ATRACoherus BiosciencesNASDAQ: CHRSNektar TherapeuticsNASDAQ: NKTRRedHill Biopharma LtdNASDAQ: RDHLSpero TherapeuticsNASDAQ: SPRO

Portfolio news

latest coverage across their companies

Fund performance · per public LP disclosures

as of Jun 2024
FundVintageCommittedNet IRRTVPIDPI
HealthCare Royalty Partners III, L.P.LPs: Florida State Board of Administration20079.1%1.27x1.27x

Source: public limited-partner disclosures (CalPERS, CalSTRS). Net IRR / TVPI / DPI as reported by the limited partner; a fund's early-year IRR is an interim estimate (J-curve).

Frequently asked questions

How many investments has HEALTHCARE ROYALTY PARTNERS made?
HEALTHCARE ROYALTY PARTNERS has 77 tracked investments, including 1 dated in the last 24 months.
What sectors does HEALTHCARE ROYALTY PARTNERS focus on?
HEALTHCARE ROYALTY PARTNERS focuses on Biotech, Healthtech.
Where is HEALTHCARE ROYALTY PARTNERS located?
HEALTHCARE ROYALTY PARTNERS is headquartered in New York, US.
Who does HEALTHCARE ROYALTY PARTNERS co-invest with?
HEALTHCARE ROYALTY PARTNERS most often shares deals with Foresite Capital, New Enterprise Associates (NEA), Sofinnova Ventures, among 30 tracked co-investors.

Images

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