Pivotal Life Sciences
Crossover fundSan Francisco · Seed–Late Stage · 15 people tracked
Also known as Pivotal bioVenture Partners · Pivotal bioVenture Partners CNS · Pivotal bioVenture Partners CNS SLP · PIVOTAL BIOVENTURE PARTNERS INVESTMENT ADVISOR LLC · Pivotal bioVenture Partners SLP
Investment thesis
Pivotal Life Sciences invests across all company stages, with a primary emphasis on 'high impact' therapeutics. The firm targets solutions that address growing unmet medical needs and offer near-curative or otherwise transformative disease-management potential. Its name reflects both its investment approach and the pivotal role it aims to play in the companies it backs.
Source: firm website, verified Aug 3, 2026.
Team · 15 people
from the firm's website & public directoriesWhat they invest in
from 3 of 3 portfolio companiesBiotech ×2AI & Machine Learning ×1Deep Tech ×1Enterprise Software ×1Fintech ×1SaaS ×1
HQs:United States×2
Investments · 3 tracked
founders shown can be your intro pathBy year:2025 · 12020 · 12 dated
BiotechSouth San Francisco, US
Tracy Saxton(Director)Grant E Pickering(Executive Officer, Director, Promoter)Jeff Fairman(Executive Officer)Ashish Khanna(Executive Officer)William Newell(Director)Patrick Enright(Director)
Board seatRob Hopfner· per SEC Form D · $110M raise · filed Apr 2020
Plexium is a targeted protein degradation company developing small molecule therapeutics for treating diseases with high unmet medical needs using their proprietary DELTA Discovery platform.
AI & Machine LearningBiotechDeep TechSan Diego, US
Michael Martin, Ph.D.(Chief Executive Officer, President)Jorge F. DiMartinoMichael Martin(President, Chief Executive Officer)
BoardMike Grey(Executive Chairman)in
Board seatRob Hopfner· per SEC Form D · $60.1M raise · filed Aug 2025
Ark provides a customizable digital platform for venture capital and private equity firms to manage investor communications, performance reporting, and document sharing with their limited partners.
Enterprise SoftwareFintechSaaS
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Exits · 1
IPOs and acquisitions across the tracked portfolioSutroVaxNASDAQ: PCVX
Frequently asked questions
- What stage does Pivotal Life Sciences invest at?
- Pivotal Life Sciences invests at the Seed, Series A, Series B, Series C, Growth, Late Stage stages.
- What sectors does Pivotal Life Sciences focus on?
- Pivotal Life Sciences focuses on Biotech, Digital Health, Healthtech, Medical Devices.
- Where is Pivotal Life Sciences located?
- Pivotal Life Sciences is headquartered in San Francisco, US.
- Does Pivotal Life Sciences lead rounds?
- Pivotal Life Sciences typically participates in rounds rather than leading them.
Images
Co-investors · 33
DCVC (Data Collective) is a venture capital firm that backs founders building companies which apply technology to major challenges across areas such as energy, biotech, agriculture, and machine learning.
The Column Group (TCG) is a venture capital firm focused on building and backing biotechnology companies, applying an edge-to-edge investment model centered on company formation with capacity for long-term private and public capital support.
Abingworth is a life science venture capital firm that backs early-stage biopharma and biotech companies, helping entrepreneurs translate scientific discoveries into new therapeutics.
SV Angel is an investment firm that partners with and supports founders building transformative companies, providing long-term backing and close advisory relationships.
Norwest is a venture and growth equity investment firm that has backed over 700 companies across sectors including AI, retail, and healthcare, working alongside entrepreneurs from early to late-stage growth.
Canaan is an early-stage venture capital firm backing founders with transformative ideas across technology and healthcare.
F-Prime Capital Partners is a venture capital firm whose team of scientists, engineers, physicians, operators, and investors supports companies in scaling and accelerating growth.
Revolution is an investment firm that has backed founders, communities, and ideas for over two decades, spanning venture capital, entrepreneurship advocacy, and real estate and hospitality investments.
Maveron is a venture capital firm that partners with founders building consumer-facing businesses, emphasizing vision and people over transactions.
Operator Partners is an investment firm run by operators that invests its own capital in technology companies from inception through Series B.
Flatiron Health is a healthcare technology and oncology data company that combines AI-powered technology, clinical expertise, and real-world oncology data to support cancer care and research. It operates one of the world's largest oncology datasets and provides point-of-care technology to oncologists.
Atlas Venture is a life sciences venture capital firm with three decades of experience investing in and building biotech and medical innovation companies, including startups launched from its own incubator.
▶21 more co-investors
boldstart venturesOrbiMedEarlybird Venture CapitalRA CapitalScalar CapitalEQT Life SciencesOUP (Osage University Partners)Dimension CapitalSofinnova PartnersSR One Capital ManagementForbionJohnson & Johnson Innovation – JJDCDomain AssociatesSofinnova VenturesSV Health InvestorsInkefRiverVest VentureRiverVest Venture PartnersJMI EquityLongitude CapitalBVCF
Firms observed investing alongside Pivotal Life Sciences, from public investor directories. Shared companies are the overlap with Pivotal Life Sciences's recorded portfolio.
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