Fundraising Fox

Pivotal Life Sciences

Crossover fund

San Francisco · Seed–Late Stage · 15 people tracked

Also known as Pivotal bioVenture Partners · Pivotal bioVenture Partners CNS · Pivotal bioVenture Partners CNS SLP · PIVOTAL BIOVENTURE PARTNERS INVESTMENT ADVISOR LLC · Pivotal bioVenture Partners SLP

Fox Verdict
Sign up to see your fit

Investment thesis

Pivotal Life Sciences invests across all company stages, with a primary emphasis on 'high impact' therapeutics. The firm targets solutions that address growing unmet medical needs and offer near-curative or otherwise transformative disease-management potential. Its name reflects both its investment approach and the pivotal role it aims to play in the companies it backs.

Invests inBiotechDigital HealthHealthtechMedical DevicesAsia-PacificChinaEuropeNorth AmericaSan FranciscoUnited StatesWilmington

Source: firm website, verified Aug 3, 2026.

Stage
Seed–Late Stage
HQ
San Francisco, California, US
Leads rounds
Follows
Instruments
Equity
Founded
2017
AUM
$2B
VC funds
2
Tracked investments
3

Team · 15 people

from the firm's website & public directories
Benjamin Li· Vice Presidentin
Joseph Charalel· Vice Presidentin

What they invest in

from 3 of 3 portfolio companies

Biotech ×2AI & Machine Learning ×1Deep Tech ×1Enterprise Software ×1Fintech ×1SaaS ×1

HQs:United States×2

Investments · 3 tracked

founders shown can be your intro path

By year:2025 · 12020 · 12 dated

SutroVaxNASDAQ: PCVXMar 2020SEC filingmedium confidence

BiotechSouth San Francisco, US

Tracy Saxton(Director)Grant E Pickering(Executive Officer, Director, Promoter)Jeff Fairman(Executive Officer)Ashish Khanna(Executive Officer)William Newell(Director)Patrick Enright(Director)

Board seatRob Hopfner· per SEC Form D · $110M raise · filed Apr 2020

Plexiumplexium.cominJul 2025SEC filingmedium confidence

Plexium is a targeted protein degradation company developing small molecule therapeutics for treating diseases with high unmet medical needs using their proprietary DELTA Discovery platform.

AI & Machine LearningBiotechDeep TechSan Diego, US

Michael Martin, Ph.D.(Chief Executive Officer, President)Jorge F. DiMartinoMichael Martin(President, Chief Executive Officer)

BoardMike Grey(Executive Chairman)in

Board seatRob Hopfner· per SEC Form D · $60.1M raise · filed Aug 2025

Ark PESarkpes.com

Ark provides a customizable digital platform for venture capital and private equity firms to manage investor communications, performance reporting, and document sharing with their limited partners.

Enterprise SoftwareFintechSaaS

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

Exits · 1

IPOs and acquisitions across the tracked portfolio

SutroVaxNASDAQ: PCVX

Frequently asked questions

What stage does Pivotal Life Sciences invest at?
Pivotal Life Sciences invests at the Seed, Series A, Series B, Series C, Growth, Late Stage stages.
What sectors does Pivotal Life Sciences focus on?
Pivotal Life Sciences focuses on Biotech, Digital Health, Healthtech, Medical Devices.
Where is Pivotal Life Sciences located?
Pivotal Life Sciences is headquartered in San Francisco, US.
Does Pivotal Life Sciences lead rounds?
Pivotal Life Sciences typically participates in rounds rather than leading them.

Images

Pivotal Life Sciences photoPivotal Life Sciences photoPivotal Life Sciences photoPivotal Life Sciences photoPivotal Life Sciences photoPivotal Life Sciences photo

Co-investors · 33

DCVC (Data Collective)

DCVC (Data Collective) is a venture capital firm that backs founders building companies which apply technology to major challenges across areas such as energy, biotech, agriculture, and machine learning.

Both backed · 1
$5M – $25M
The Column Group

The Column Group (TCG) is a venture capital firm focused on building and backing biotechnology companies, applying an edge-to-edge investment model centered on company formation with capacity for long-term private and public capital support.

Both backed · 1
$30M
Abingworth

Abingworth is a life science venture capital firm that backs early-stage biopharma and biotech companies, helping entrepreneurs translate scientific discoveries into new therapeutics.

Both backed · 1
$15M – $30M
SV Angel

SV Angel is an investment firm that partners with and supports founders building transformative companies, providing long-term backing and close advisory relationships.

Norwest Venture Partners

Norwest is a venture and growth equity investment firm that has backed over 700 companies across sectors including AI, retail, and healthcare, working alongside entrepreneurs from early to late-stage growth.

$10M – $30M
Canaan Partners

Canaan is an early-stage venture capital firm backing founders with transformative ideas across technology and healthcare.

$500K – $20M
F-Prime Capital Partners

F-Prime Capital Partners is a venture capital firm whose team of scientists, engineers, physicians, operators, and investors supports companies in scaling and accelerating growth.

$3M – $10M
Revolution

Revolution is an investment firm that has backed founders, communities, and ideas for over two decades, spanning venture capital, entrepreneurship advocacy, and real estate and hospitality investments.

$100K – $1M
Maveron

Maveron is a venture capital firm that partners with founders building consumer-facing businesses, emphasizing vision and people over transactions.

$5M – $10M
Operator LP

Operator Partners is an investment firm run by operators that invests its own capital in technology companies from inception through Series B.

$250K – $300K
Flatiron Health

Flatiron Health is a healthcare technology and oncology data company that combines AI-powered technology, clinical expertise, and real-world oncology data to support cancer care and research. It operates one of the world's largest oncology datasets and provides point-of-care technology to oncologists.

Atlas Venture

Atlas Venture is a life sciences venture capital firm with three decades of experience investing in and building biotech and medical innovation companies, including startups launched from its own incubator.

$500K – $1M
21 more co-investors

boldstart venturesOrbiMedEarlybird Venture CapitalRA CapitalScalar CapitalEQT Life SciencesOUP (Osage University Partners)Dimension CapitalSofinnova PartnersSR One Capital ManagementForbionJohnson & Johnson Innovation – JJDCDomain AssociatesSofinnova VenturesSV Health InvestorsInkefRiverVest VentureRiverVest Venture PartnersJMI EquityLongitude CapitalBVCF

Firms observed investing alongside Pivotal Life Sciences, from public investor directories. Shared companies are the overlap with Pivotal Life Sciences's recorded portfolio.

Similar investors

Featured in lists