GreatPoint Ventures
Venture capitalActively deployingSan Francisco · Seed–Series B · 18 people tracked
Also known as GREATPOINT INVESTMENT MANAGEMENT, LLC · GreatPoint Ventures Innovation
Investment thesis
GreatPoint Ventures positions itself as an entrepreneur-first, in-the-trenches investor guided by the motto 'Make no little plans,' seeking revolutionary rather than incremental ideas that transform industries and benefit society. The firm deliberately makes fewer than ten new investments per year so it can work closely with each team, helping founders recruit top talent and build key industry relationships. It emphasizes early-stage investing and long-term commitment, backing companies through obstacles over the long haul. Areas it cites as examples of positive change include affordable healthier foods, curing diseases, and helping first responders save lives.
Source: firm website, verified Aug 3, 2026.
Team · 18 people
from the firm's website & public directories
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What they invest in
from 44 of 95 portfolio companiesAI & Machine Learning ×22Enterprise Software ×18Healthtech ×14Data & Infrastructure ×10SaaS ×10Developer Tools ×7Cloud Computing ×6Digital Health ×6
HQs:United States×41Mexico×1
Investments · 95 tracked
founders shown can be your intro path
Beyond Meat creates plant-based protein products, including burgers and other foods designed to provide nutritional value while supporting environmental sustainability and soil regeneration.
Advanced ManufacturingAgTechClimate TechFoodTechEl Segundo, US
Ethan Brown(Founder & CEO)Colleen Jay(Director)Teri L. Witteman(Executive Officer)Nandita Bakhshi(Director)Jonathan Nelson(Executive Officer)Raymond J. Lane(Director)
Onymos builds software development components and platform services that companies integrate into their web and mobile applications, handling front-end, back-end, and data functionality.
Cloud ComputingDeveloper ToolsHealthtechSaaSRedwood Shores, US
SHIVAGURU NATHAN(Executive Officer, Director)Shiva Nathan(Founder)Bhavani Vangala(CTO)
Seraphic provides browser security software for enterprises, embedding adaptive security directly into browsers to protect against phishing, advanced threats, and data risks while preserving productivity.
CybersecurityEnterprise SoftwareSaaS
Ilan Yeshua(CEO & Co-founder)inAvihay Cohen(CTO & Co-founder)inSuresh Batchu(COO & Co-Founder)in
Activ Surgical develops digital surgery imaging technology that uses augmented reality, artificial intelligence, and machine learning to help surgeons visualize critical physiological structures during surgery.
AI & Machine LearningHealthtechMedical DevicesBoston, US
Michael Ruehlman(Executive Officer)Emily Casey(Director)David Wells(Director)Peter Kim(Director)Todd Usen(Executive Officer, Director)
Board seatAshok Krishnamurthi· per SEC Form D
Biobot pioneers wastewater epidemiology, monitoring pathogens and substances in sewage to provide real-time public health surveillance at the community level.
BiotechData & InfrastructureGovTechHealthtechBoston, US
Newsha Ghaeli(Cofounder & President)inMariana Matus(Founder)inVivek Pattipati(Director)Andrew Perlman(Director)Mariana Guadalupe Matus Garcia(Executive Officer, Director)
Board seatAndrew Perlman· per SEC Form D · $13.6M raise · filed Jun 2025
San Francisco, US
Board seatAshok Krishnamurthi· per SEC Form D · $10.5M raise · filed Mar 2021
Tucker, US
Andrew Perlman(Director)James Dahlman(Executive Officer, Director)Julie Sunderland(Director)
Board seatAndrew Perlman· per SEC Form D
Reston, US
Jared N Shepard(Executive Officer, Director)Jerry Raphael(Executive Officer)James Cushman(Executive Officer, Director)
BoardJohn M. Murray(Director)Richard Sawchak(Director)
Board seatRay Lane· per SEC Form D · $12.3M raise · filed Jan 2025
Portola Valley, US
William Deihl(Executive Officer)Jason Camm(Director)Steven T. Kent(Executive Officer, Director)Harold Kent(Executive Officer, Director)
Board seatAndrew Perlman· per SEC Form D · $25M raise · filed Apr 2023
Austin, US
Steve Jurvetson(Director)David Fick(Executive Officer, Director, Promoter)Michael Henry(Executive Officer, Director, Promoter)
BoardShahin Farshchi(Director)
Board seatAndrew Perlman· per SEC Form D · $23.7M raise · filed Feb 2023
KlearNow provides AI infrastructure for supply chain trade intelligence and compliance management.
AI & Machine LearningEnterprise SoftwareLogistics & Supply Chain
Board seatAshok Krishnamurthi· per SEC Form D
BiotechNorth Brunswick, US
Manish Arora(Executive Officer, Director)
BoardRafi Syed(Director)Amol Deshpande(Director)
Board seatAshok Krishnamurthi· per SEC Form D · $10M raise · filed Aug 2024
Sirona Medical builds RadOS, a cloud-native platform that reimagines radiology practice in the AI age for physicians and radiology practices.
AI & Machine LearningDigital HealthHealthtechSan Francisco, US
Cameron Andrews(Founder & President)Ankit Goyal(Executive Officer, Director)Francisco Gimenez(Director)
Board seatAndrew Perlman· per SEC Form D
Ark provides a customizable digital platform for venture capital and private equity firms to manage investor communications, performance reporting, and document sharing with their limited partners.
Enterprise SoftwareFintechSaaS
Atlas Health uses AI-driven patient assistance to help health systems connect patients to financial resources and reduce barriers to care.
AI & Machine LearningDigital HealthEnterprise SoftwareHealthtech
Berwyn, US
Kanishka Rao(Executive Officer, Director)Bharat Rao(Executive Officer, Director)
Chronosphere provides an observability platform for microservices and containers that helps teams detect and fix customer-impacting issues while controlling costs and complexity.
Cloud ComputingData & InfrastructureDeveloper ToolsPalo Alto, US
MARTIN CHEN MAO(Executive Officer, Director)ROBERT JAMES SKILLINGTON(Executive Officer, Director)
Confluent provides a cloud-native platform for real-time data streaming and movement, enabling organizations to connect applications and respond to business events as they occur.
AI & Machine LearningCloud ComputingData & InfrastructureEnterprise SoftwareMountain View, US
Neha Narkhede(Founder)
Chicago, US
Arsen Avakian(Executive Officer, Director)Gregory Wasson(Director)Glen Tullman(Executive Officer, Director)
Devoted Health offers Medicare Advantage plans and integrated healthcare services for older Americans, including virtual and in-home care, member support guides, and coordination with local providers across 29 states.
HealthtechInsurTechUnited States, US
Todd Park(Executive Officer, Director)Bryan Roberts(Director)Edward Park(Executive Officer, Director)Robert Kocher(Director)William Frist(Director)Kathleen Sebelius(Director)
Diffuse designs proteins using AI models trained on experimental data collected through proprietary assays and software, delivering validated AI-designed proteins to partners.
AI & Machine LearningBiotechDeep TechHealthtechSan Francisco, US
Namrata Anand(Founder)in
Even Financial operates a financial marketplace network that matches consumers with financial products through precision targeting and personalization.
B2B MarketplacesFintechMarketing TechBrooklyn, US
Phill Rosen(Founder & CEO)Ian Rosen(Executive Officer, Director)Jarid Maged(Executive Officer, Director)
BoardBrendan Dickinson(Director)
Austin, US
Raymond J. Lane(Director)Brett Meyerowitz(Director)Reinhard Ekl(Executive Officer)Steven Raucher(Executive Officer, Director)
San Francisco, US
Wade Khadder(Executive Officer, Director)Jocelyn Goldfein(Director)
BiotechCambridge, US
Theresia Guow(Director)Sirshendu Roopom Banerjee(Executive Officer)Gabriel Kwong(Executive Officer)Stan Lapidus(Director)Amy Schulman(Director)
GOOD PLANeT Foods makes plant-based cheese made with olive oil, offering products with minimal saturated fat and good melt as an alternative to dairy cheese for consumers.
Advanced ManufacturingConsumerDirect to ConsumerFoodTechBellevue, US
Joe Essa(Director)Michael Frey(Director)Dan Gross(Director)David Israel(Founder)Josh Wand(Director)Keith Kravcik(Director)
Abett offers a data management platform that integrates, validates, and manages healthcare and benefits data for large employers and health plans.
Data & InfrastructureEnterprise SoftwareHealthtech
Hero is a direct-to-consumer brand that produces and sells low-carb and nutritionally-optimized pasta, bread, bagels, and other baked goods.
Direct to ConsumerFoodTech
Austin, US
Richard E Anderson(Director)Brian Vetter(Executive Officer, Director)Simon Yoo(Director)Justin Marston(Executive Officer, Director)
Inkeep provides a platform for building and deploying AI agents and automations through both code and visual interfaces, serving developers and non-technical users who need to automate customer support, sales, and internal workflows.
AI & Machine LearningDeveloper ToolsEnterprise SoftwareSan Francisco, US
Mundo AI creates a multilingual dataset library to address the scarcity of high-quality training data in languages other than English for AI model development.
AI & Machine LearningData & InfrastructureEnterprise SoftwareSan Francisco, US
Jason Liao(CEO and Founder)inNaijide Anwaer(Founder)inGarreth Lee(Founder)inKenneth Wu(Founder)in
Aurora, US
Alan Hahn(Executive Officer, Director, Promoter)Peter Lubar(Director)Sanjeev Krishnan(Director)Scott Horner(Director)Ephraim Lindenbaum(Director)Robert Schier(Director)
Nixtla provides enterprise-grade forecasting and anomaly detection platform using AI/ML techniques like TimeGPT for time series analysis.
AI & Machine LearningData & InfrastructureEnterprise SoftwareFintechMexico City, MX
Max Mergenthaler Canseco(Executive Officer, Director)Toni Schneider(Director)Cristian Challu(Executive Officer, Director)
BoardJuan Muldoon(Director)
Nowsta is an AI-powered workforce management platform that enables organizations to source, schedule, manage, and pay hourly and contingent workers from a unified interface with advanced scheduling, payroll integration, and compliance features.
Enterprise SoftwareHR TechSaaSBrooklyn, US
Lou Forster(Director)Moo Kim(Director)Nicholas Lillios(Executive Officer, Director)
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Frequently asked questions
- What stage does GreatPoint Ventures invest at?
- GreatPoint Ventures invests at the Seed, Series A, Series B stages.
- What is GreatPoint Ventures's typical check size?
- GreatPoint Ventures typically writes checks of $250K – $20M.
- What sectors does GreatPoint Ventures focus on?
- GreatPoint Ventures focuses on Biotech, Crypto & Web3, Defense Tech, Enterprise Software, Fintech, FoodTech, Hardware, Healthtech, Medical Devices, New Materials, Retail Tech, SaaS.
- Where is GreatPoint Ventures located?
- GreatPoint Ventures is headquartered in San Francisco, US.
- Does GreatPoint Ventures lead rounds?
- Yes, GreatPoint Ventures leads investment rounds.
Media · Podcasts & interviews
featuring the teamHacking Postgres S2E10: DJ Patil and Ray Lane, GreatPoint Ventures
Tembo · Ray Lane
Entrepreneurship Bootcamp: Fireside Chat with Ray Lane, GreatPoint Ventures
CMU Swartz Center for Entrepreneurship · Ray Lane
New Normal: Ray Lane of GreatPoint Ventures
Deal Architect Inc · Ray Lane
Ray Lane of GreatPoint Ventures Describes Why He Invested in Kinetica
Kinetica · Ray Lane
Images
Co-investors · 50
Menlo Ventures is a venture capital firm that backs transformative, early-stage technology companies reshaping how people live and work.
Cathay Innovation is a multi-stage venture capital firm founded in Paris in 2015 that invests in startups building technologies transforming how people live and work, backed by industry and corporate partners.
GV (formerly Google Ventures) is a venture investment firm that backs founders across many industries, aiming to build long-term relationships and support companies across multiple stages and milestones.
Greylock Partners is a venture capital firm that backs founders at the earliest stages, often as their first investor before a product exists.
Index Ventures is a venture capital firm that backs founders across the globe, investing in the people behind ideas from early through later stages.
NextView Ventures is a seed-stage venture capital firm that works closely with founders, providing hands-on support to help build companies from inception to scale.
Andreessen Horowitz's Strategic Partnerships page describes collaborations that connect its portfolio companies with established institutions to help scale and deploy their technology.
General Catalyst is a venture capital and investment firm that backs founders across industries, with a strong focus on AI-driven transformation, fintech, healthcare, and other sectors.
Accel is a venture capital firm that partners with exceptional founding teams, positioning itself as a first partner to startups globally.
True Ventures is an early-stage venture capital firm that writes the first check for founders and supports them through subsequent stages of growth.
Bond is a venture capital fund spun out from Kleiner Perkins that combines Mary Meeker's famous multi-hundred-page "Trends" reports with late-stage investing, positioning itself as both a macro research house and capital provider for category-defining Internet and software businesses. The fund operates with a small, senior-heavy partnership that blends operators and growth investors, focusing on companies that have already proven product-market fit and helping them architect global expansion and IPO readiness.
8VC is a technology investment firm that builds and invests in ambitious companies across sectors including life sciences, healthcare, manufacturing, enterprise, logistics, and defense.
▶38 more co-investors
AbstractVenrockPolaris PartnersGolden VenturesDrive CapitalShield CapitalLightspeed Venture PartnersCraft VenturesUncork CapitalBenchmarkSV AngelFirst Round CapitalCRV (Charles River Ventures)Union Square Ventures (USV)FloodgateSouth Park CommonsIA VenturesNext47GustoMatrixUncorrelated VenturesCyberstartsFuel Venture CapitalNext Play VenturesAIX VenturesSaga VenturesTeamworthy VenturesThird Kind Venture CapitalConvictionEuclid Venture PartnersRace CapitalS32PIPELINE CAPITAL PARTNERSBain Capital CryptoCrowdStrikeNew Markets Venture PartnersHarpoon VenturesARK Investment Management
Firms observed investing alongside GreatPoint Ventures, from public investor directories. Shared companies are the overlap with GreatPoint Ventures's recorded portfolio.
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