Keyhorse Capital

Advanced Energy Materials develops hydrodesulfurization and fuel upgrading catalysts for refinery applications, addressing desulfurization needs across different hydrogen availability scenarios.

CleantechEnergyNew Materials

Airtrek builds autonomous robots for aircraft ground operations, including wingwalking support during towing and inspection tasks. The robots use LiDAR and camera perception to monitor aircraft movements, detect foreign objects, and inspect surfaces, serving airport ramp operations teams.

AI & Machine LearningHardwareRobotics

Beverage and ingredient innovation for the modern pantry.

Another Nine operates private indoor golf simulator suites equipped with Trackman technology, offering 350+ courses and practice ranges for flexible hourly bookings without membership requirements. The company serves golfers of all skill levels seeking convenient, anytime access to golf entertainment.

ConsumerColumbia, US

Two founders (names not specified)

AquiSense develops UV-C LED-based water disinfection systems for residential, commercial, and industrial applications without the use of chemicals. The company also provides air and surface disinfection products and research tools for laboratory use.

CleantechHardwareIoTKentucky, US

AuraSense builds physics-informed AI software that analyzes human movement from video in real-time, delivering biomechanical insights for gaming, sports, and clinical research applications.

AI & Machine LearningDeep TechHardware

AuthoFi provides an automated platform for healthcare pre-authorization processing that integrates with existing insurance workflows to reduce administrative burden and claims denials. The solution serves healthcare payers and providers managing prior authorization processes.

Enterprise SoftwareHealthtechSaaS

Avana Health develops treatments for abnormal uterine bleeding and postpartum hemorrhage, targeting unmet needs in women's health. The company is in clinical development of uterine health treatments designed to be safe, effective, and accessible globally.

BiotechFemTechHealthtech

Bailout Systems develops hands-free descent technology for professionals working in high-stakes environments where safe controlled descent is critical. The systems are lightweight, portable, and designed to reduce training requirements and allow users to focus on their primary task rather than their descent.

Hardware

Michael Ragsdale(Founder and CEO)

BehaVR develops virtual reality therapeutics that address mental and behavioral health conditions including anxiety, stress, pain management, addiction recovery, and maternal health. The company delivers evidence-based VR programs designed to build coping skills and help patients manage trauma, triggers, and fears.

Digital HealthHealthtechMental Health

Beltways develops modular pedestrian conveyance systems (accelerators) designed to move large volumes of people quickly over short distances, competing with trains and vehicles for urban transit. The systems use proprietary OS software for motion control and predictive maintenance.

HardwareMobility & Transportation

Bexion Pharmaceuticals develops BXQ-350, a biologic therapy that targets sphingolipid metabolism to enhance cancer cell death and improve the effectiveness of standard therapies in patients with advanced solid tumors, particularly metastatic colorectal cancer.

BiotechMedical Devices

BeyondWill is a software platform that helps independent financial advisors identify growth opportunities in their client books by analyzing estate plans to surface held-away assets, life events, and at-risk inheritances. The platform integrates with advisors' existing CRM systems and can monitor both uploaded client plans and those prepared through attorney-approved templates.

Enterprise SoftwareFintechSaaS

Bioglitz produces a plant-based glitter adhesive and skincare serum made from algae that holds cosmetic glitz designs while moisturizing skin. The product is marketed as a beauty and personal care item for consumers seeking long-lasting glitter looks.

BiotechConsumer

Biscuit Belly is a casual dining restaurant that serves scratch-made biscuits baked fresh daily, along with biscuit sandwiches, brunch items, and a curated selection of coffee and alcohol. The restaurant operates in the foodservice sector, offering Southern-style comfort food in a quick-casual dining format.

ConsumerFoodTech<UNKNOWN>

Blue Sky Case Management is a Kentucky-based Medicaid case management agency serving adults and children with intellectual and developmental disabilities. The company connects clients with waiver programs (SCL, Michelle P. Waiver, and PDS) to enable community living and independent life choices.

HealthtechKentucky, US

Joseph J. MacDonald(Co-Founder & President & Chief Executive Officer)Tara Clarkson(Co-Founder, Executive Director)Chris Lanham(Co-Founder, Referral Director, Billing Consultant)Brittney McConville(Co-Founder, Director of Business Information Systems)

BrainSTEM offers summer STEAM camps for children in grades 3-9, teaching 3D printing, game development, artificial intelligence, coding, drones, and robotics through in-person and virtual formats in Louisville, Kentucky.

EdTechImpact & Social GoodLouisville, US

Ricky Mason(Founder)

C2 Keep provides software for controlled substance inventory management in pharmacies, helping practitioners comply with the Controlled Substance Act. The solution replaces manual logbook processes to reduce compliance risk and administrative burden.

HealthtechSaaS

David GalowniaDan Murphy

CleanSpace is a mobile app that connects customers with background-checked cleaners for on-demand residential cleaning services across the United States. The platform allows users to book same-day cleaning appointments, manage recurring services, and pay through a single app.

ConsumerMarketplaces

Cloverleaf provides automated coaching and assessment solutions that integrate into employees' daily workflows to help organizations develop their talent and enable individuals to perform their best work.

AI & Machine LearningEnterprise SoftwareHR TechSaaS<UNKNOWN>

Cognision develops an objective measurement system for evaluating patients with cognitive disorders including concussion, mTBI, and dementia, serving clinicians, pharmaceutical companies, and researchers through brain-based biomarkers and qEEG/ERP testing.

AI & Machine LearningDigital HealthMedical Devices

ConnectRate provides AI-powered phone number validation for sales teams to increase connect rates on outbound calling. The platform validates phone numbers and predicts which will answer, helping sales development representatives reach decision-makers more efficiently.

AI & Machine LearningSaaSSales Tech

Content Credits provides a pay-per-article monetization layer for digital publishers, allowing casual readers to unlock individual articles without committing to subscriptions. The platform includes engagement analytics and upcoming tools to track and monetize AI-driven content access and zero-click search traffic.

Marketing TechMedia & EntertainmentSaaS

DataRovers provides AI-powered denial management software for healthcare revenue cycle management teams to identify, analyze, and appeal insurance claim denials. The platform automates appeal letter generation, prioritizes claims by recovery potential, and integrates with major EHR systems to help health systems reduce denial rates and recover lost revenue.

AI & Machine LearningHealthtechSaaS

Deepshot provides AI tools for video content creation, specifically focusing on lip-sync generation using generative AI technology. The platform is designed for content creators to modify video content with minimal effort.

AI & Machine LearningCreator EconomyMedia & Entertainment

DesiCorp develops advanced packaging and stabilization solutions for biopharmaceutical and therapeutic products, extending shelf-life without refrigeration to improve access in rural, remote, and emergency care settings. The company uses specialized materials and two-chambered packaging designs to preserve sensitive compounds during transport and storage in austere environments.

BiotechHealthtechNew Materials

Brett Janis(CEO/CSO, Treasurer, and Co-founder)Jonathan Kopechek(Secretary and Co-founder)Michael Menze(President and Co-founder)

Ecoshell produces eggshell-derived bio-calcium additives and resins for plastic reduction, helping brands develop sustainable plastic alternatives and meet environmental mandates. The company offers design, manufacturing, and sourcing services from its Asia-based network to bring eco-certified products to market.

Advanced ManufacturingCircular EconomyCleantechTaiwan, TW

Elixir Kombucha produces raw, unpasteurized kombucha in multiple flavors sold direct-to-consumer through cans and subscription boxes. The company targets consumers focused on gut health and wellness beverages.

Direct to ConsumerFoodTechWellness & Fitness

Endoprotech develops anti-inflammatory liposome therapeutics that modify cell plasma membranes to address microvascular dysfunction, with a focus on reducing injury and recovery time in cardiac conditions.

BiotechDeep TechMedical Devices

Enviro-Fresh manufactures sealed compartment storage systems for towels and linens in healthcare facilities and hospitality settings. The product reduces laundering costs and environmental impact while maintaining hygiene standards through tamper-evident indicators.

HardwareHealthtechImpact & Social Good

Mary fox(Accountant)

EQL is a game studio and lottery content provider that creates and distributes lottery games for lottery operators and players in the US and internationally. The company develops original games and aggregates third-party content to modernize traditional lottery offerings.

Gaming

ROIHire is a platform that helps employers optimize hiring decisions by aggregating workforce data and connecting them to available federal and state hiring incentives while estimating candidate retention probability. The platform serves employers and workforce partners seeking to reduce hiring risk, access unclaimed incentives, and improve retention outcomes.

Data & InfrastructureEnterprise SoftwareHR TechKentucky, US

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Feed Coyote is an all-in-one project management platform designed for freelancers and professionals to collaborate, communicate, and manage work across 130+ countries. The platform includes built-in tools for payments tracking, deadline management, and team communication.

B2B MarketplacesFintechFuture of WorkSaaSPaducah, US

Heybesti offers personalized period care and perimenopause solutions through customizable monthly subscription boxes delivered alongside a free cycle and symptom tracking app, serving women seeking tailored menstrual health products and wellness essentials.

Direct to ConsumerFemTechWellness & Fitness

The Kentucky Science and Technology Corporation (KSTC) is a state organization that accelerates innovation-driven economic growth and supports entrepreneurship across Kentucky. It operates regional innovation hubs, manages STEM education initiatives, and coordinates economic development programs throughout the commonwealth.

EdTechGovTechKentucky, US

CLMA provides predictive labor market intelligence and risk analysis tools for construction project planners and contractors. The platform helps owners, prime contractors, and subcontractors assess labor supply-demand risk, manage workforce development, and plan resource allocation across craft, engineering, and project controls disciplines.

Construction TechData & Infrastructure

Narratize is an AI-powered system of intelligence for new product development that orchestrates knowledge from PLM, ERP, and other systems of record alongside expert knowledge, delivering structured portfolio intelligence to accelerate innovation cycles for advanced manufacturers. The platform serves mid-market and enterprise manufacturers in chemicals, medical devices, aerospace, industrial equipment, CPG, energy, and electronics by centralizing product knowledge and enabling cross-functional teams to make faster, more aligned decisions.

Advanced ManufacturingAI & Machine LearningEnterprise Software

Connect provides marketing analytics and ad management tools that track revenue attribution and help customers optimize ad spending through data-driven insights. The platform serves marketing teams, operations teams, asset managers, and regional managers.

AdTechMarketing TechSaaS