/Investor DB

Epidarex Capital

Venture capitaloperating company · company profile

Bethesda · Seed–Series A · 13 people tracked

Also known as EPIDAREX CAPITAL MANAGEMENT LLC

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Investment thesis

Epidarex is a transatlantic early-stage venture capital firm that invests in and helps build breakthrough life science companies located in emerging innovation hubs. Led by a diverse team of early-stage investors, the firm positions itself as a trusted partner to founders and co-investors, leveraging deep scientific and industry networks to create value and drive shared success across its portfolio.

Source: firm website, verified Sep 29, 2026.

Stage
Seed–Series A
Check
$2.5M – $6.3M
HQ
Bethesda, Maryland, US
Leads rounds
Leads
Instruments
Equity
Founded
2010
Last 12 months
1 investment
AUM
$190.5M
VC funds
3
Tracked investments
41
Unicorns
1
Acquisitions
5

Team · 13 people

from curated & public directories
A. Sinclair Dunlop· Managing Partnerin
Henning Steinhagen· Venture Partner

Founder mafia

2 people who came through Epidarex Capital went on to found or lead other companies.

What they invest in

from 27 of 41 portfolio companies

Biotech ×24Healthtech ×15Medical Devices ×8Deep Tech ×3AI & Machine Learning ×2Digital Health ×2Longevity ×2Impact & Social Good ×1

HQs:United States×10United Kingdom×5Germany×1

Who they back

founder profiles across 8 portfolio companies
38%
solo founders
3 of 8 mapped founding teams

Founding team size:solo founder×32 founders×44+ founders×1

Investments · 41 tracked

founders shown can be your intro path

By year:2026 · 12022 · 22020 · 12016 · 12015 · 12014 · 17 dated

Harness Therapeutics Ltdharnesstx.comin✓ verified

Harness Therapeutics develops disease-modifying precision therapies for hard-to-treat neurodegenerative diseases through controlled modulation of CNS targets.

BiotechHealthtech

Jan Thirkettle(CEO Director)in

Co-investorsOno Venture Investment, Inc.Dementia Discovery FundSV Health Investors

Lunac Therapeuticslunactherapeutics.com✓ verified

LUNAC Therapeutics develops first-in-class oral and intravenous anticoagulants targeting activated Factor XII to treat and prevent thrombotic events with reduced bleeding risk.

BiotechHealthtechMedical DevicesLeeds, GB

Professor Helen Philippou(Scientific Founder)Dr. Richard Foster(Scientific Founder)

Macomicsmacomics.comin✓ verified

Macomics is a drug discovery company developing therapies that target macrophage activity for diseases with limited or ineffective treatment options.

BiotechLongevity

Co-investorsScottish EnterpriseLifelink

Nyra Medicalnyramedical.comin𝕏Nov 2022✓ verified

Nyra Medical develops the CARLEN (Cardiac Leaflet Enhancer) system, a transcatheter single-leaflet device for repairing functional mitral regurgitation while preserving native valve function.

BiotechHealthtechMedical DevicesAtlanta, US

Dr. Murali Padala(Founder)Dr. Eric Sarin(Founder, Director)Dr. Kirthana Suresh(Founder)Sai Muralidhar Padala(Executive Officer, Director)Lori Chmura(CEO)inGowri Raman(Director)

Co-investorsBroadview VenturesVensana CapitalGRA Venture

Theolyticstheolytics.com✓ verified

Theolytics develops systemically deliverable immunotherapies based on oncolytic adenoviruses designed to target solid tumours and their supporting microenvironment.

BiotechHealthtech

Co-investorsOxford Science EnterprisesSound BioventuresTaiho Ventures, LLCM Ventures

CONFLUENCE LIFE SCIENCES, INC.confluencelifesciences.cominApr 2016acquired by Aclaris Therapeutics

Technology-focused company on rational drug design for cancer and chronic inflammatory diseases (acquired by Aclaris Therapeutics in August 2017).

HealthtechSaint Louis, US

Jennifer Bohnert(Executive Officer)Walter Smith(Executive Officer, Director)Joseph Monahan(Executive Officer, Director)in

BoardDaniel Janiak(Director)Charles Bolten(Director)Thomas Smart(Director)

Board seatKyparissia Sirinakis· per SEC Form D

Hawkhill Therapeuticshawkhilltherapeutics.comApr 2026SEC filingmedium confidence

BiotechDundee, Scotland

Timothy Jason Sparey(Executive Officer)Antoine Boulanger(Executive Officer)Francisca Peixoto(Executive Officer)Christopher Andrew Woodland(Executive Officer, Director)

Board seatMary Canning· per SEC Form D · $290.5K raise · filed Sep 2026

Co-investorsO2h Ventures

Slate Bioslatebio.cominDec 2020

Slate Bio develops regulatory T cell (Treg) therapies for treating autoimmune diseases.

BiotechDigital HealthMedical DevicesCharlottesville, US

Robert Creeden(Director)Kurt Woerpel(Executive Officer)Andrew J Krouse(Executive Officer, Director)

Board seatKyparissia Sirinakis· per SEC Form D

Co-investorsVTC Ventures

Apellis Pharmaceuticalsapellis.comin𝕏acquired by Biogen · May 2026 · $5.6B

NASDAQ-listed company developing therapies for complement cascade-driven diseases in haematology, ophthalmology, and nephrology.

BiotechCrestwood, US

Pascal Deschatelets(Executive Officer)inCedric Francois(Executive Officer, Director)in

BoardGerald Chan(Director)Stephanie O'Brien(Director)Alec Machiels(Director)A. Sinclair Dunlop(Director)

Co-investorsAvoro Capital AdvisorsEMBL VenturesF-Prime CapitalKeyhorse CapitalSofinnova VenturesSolasta Ventures+1 more

Clyde Biosciences Cardiomyocyte Assayclydebio.com

Clyde Biosciences is a contract research organization offering predictive cardiac safety and efficacy testing using human iPSC-derived cardiomyocyte models, aimed at pharmaceutical and biotech teams assessing cardiotoxicity for clinical translation.

BiotechDeep TechHealthtech

Godfrey Smith(Chief Scientific Officer and Co-Founder)Francis Burton(Head of Software and Modeling & Co-Founder)Richard Henderson(Chief Executive Officer)Mark Bryant(Chief Business Officer)

Curve Therapeuticscurvetx.comin

Curve Therapeutics uses its mammalian cell-based Microcycle discovery platform to develop cyclic peptide and small molecule drugs against intracellular targets.

AI & Machine LearningBiotech

Co-investorsPfizer Venture InvestmentsColumbus Venture Partners

Dunaddunadtx.comin

Dunad Therapeutics is a biotech company developing oral small-molecule medicines using a covalent chemistry discovery platform to target neurodegenerative diseases such as ALS, Parkinson's disease, and FTD.

BiotechDeep TechCambridge, GB

Pearl Huang(President & CEO)inStephen Huhn(CMO)

Co-investorsBGVAlpha Wave Global

Edinburgh Molecular Imagingemimaging.com

University of Edinburgh spin-out clinical-phase biotech developing C-Met molecular targeting technology for cancer radiotherapy and imaging.

Co-investorsScottish Investment Bank

Enterprise Therapeuticsenterprisetherapeutics.comin𝕏

Enterprise Therapeutics is a drug discovery company developing therapies for respiratory diseases such as cystic fibrosis, asthma, and COPD.

BiotechHealthtechBrighton, GB

John Ford(Co-founder)inMartin Gosling(Founder)in

Co-investorsNovartis Venture FundVersant VenturesForbionIP GroupPanakes Partners

Epsilogenepsilogen.comin

Epsilogen develops antibody therapeutics based on the IgE, IgA, and IgG immunoglobulin isotypes for the treatment of cancer, matching each isotype to specific tumor types and combining isotypes into single antibody molecules.

BiotechHealthtech

Tim Wilson(Chief Executive Officer)Kevin FitzGerald(Chief Scientific Officer)inCristina Oliva(Chief Medical Officer)inNick Robbins-Cherry(Chief Financial Officer)inElizabeth Hardaker(Chief Translational Science Officer)

Co-investors3B Future Health FundAlbionVCBioGeneration VenturesGlobal BioAccess FundNovartis Venture FundUCL Technology Fund

Kidneykidney.orgin

The National Kidney Foundation works to eliminate preventable kidney disease, accelerate innovation in patient care, and address structural inequities in kidney treatment and transplantation services.

HealthtechImpact & Social Good

Co-investorsYsios CapitalBioGeneration VenturesRoche Venture FundScottish National Investment BankSofinnova Partners

Kodikaz websitekodikaz.comin𝕏

Kodikaz develops Zip-Code, a non-viral cell-specific delivery platform for gene therapy applications, particularly focused on oncology and cancer treatments.

AI & Machine LearningBiotechMedical DevicesAtlanta, US

Anthony Johnson(Co-Founder & CEO)inDr. Leon Bernal-Mizrachi(Co-Founder, CSO)in

Co-investorsGRA VentureIllumina Ventures

Lariotxlariotx.com

Lario Therapeutics develops first-in-class precision medicines aimed at disease-modifying treatments for severe neurological disorders, including developmental and epileptic encephalopathies and Parkinson's disease.

BiotechDeep Tech

Leucidleucid.com

Leucid Bio develops CAR-T cell therapies based on a proprietary Lateral CAR platform that redesigns the CAR structure to mimic the lateral signalling arrangement of natural immune receptors.

BiotechHealthtechLondon, GB

John Maher(Founder)

Co-investorsSofinnova PartnersVulpes Investment Management

Libra Therapeuticslibratherapeutics.comin𝕏

Libra Therapeutics develops small molecule therapeutics targeting lysosomal function and autophagy to treat neurodegenerative diseases including ALS, Parkinson's, Alzheimer's, and Huntington's disease.

BiotechLongevityMedical Devices

Dr. Gill(Chief Scientific Officer)

Co-investorsDolby Family VenturesAMR Action FundBoehringer Ingelheim Venture Fund

Mironidmironid.comin𝕏

Mironid is a drug development company building a pipeline of therapies targeting cAMP-degrading phosphodiesterase enzymes to treat Autosomal Dominant Polycystic Kidney Disease (ADPKD) and other rare kidney diseases.

BiotechMedical Devices

Adele Rowley(Chief Scientific Officer)in

Co-investorsBioGeneration VenturesRoche Venture FundSofinnova PartnersScottish National Investment Bank

RapidPulserapidpulsemed.com

RapidPulse Medical is an investor relations page showcasing multiple healthcare-focused investment firms and incubators that back medical device and healthcare technology companies.

BiotechDigital HealthHealthtechMedical Devices

Co-investorsBroadview VenturesFlorida Opportunity FundHatteras Venture PartnersS3 VenturesSante Ventures

Rezeranodthera.comin𝕏

NodThera develops clinical-stage small-molecule therapies targeting inflammation for cardiometabolic and neuroinflammatory diseases, including cardiovascular disease, metabolic dysfunction, and neuroinflammation.

BiotechHealthtech

Geoff McDonough(Executive Team / Board)inChris Guiffre(Executive Team)inAlan P. Watt(Executive Team)inJyothis George(Chief Medical Officer)inNick Clarke(Executive Team)in

Co-investors5AM VenturesF-Prime CapitalSanofi VenturesSofinnova Partners

Ryme Medicalrymemedical.com

Ryme Medical develops a catheter-based therapy to treat chronic obstructive pulmonary disease (COPD) by reducing airway inflammation and improving patient outcomes.

BiotechHealthtechMedical DevicesMountain View, US

Co-investorsSeroba Life Sciences

Topas Therapeuticstopas-therapeutics.comin

Topas Therapeutics develops nanoparticle-based therapies to induce immune tolerance for autoimmune and immune-mediated diseases.

BiotechHealthtech

Hugo Fry(Chief Executive Officer)inChristian Schröter(Chief Operating Officer)Cristina de Min(Chief Medical Officer)Anne Burger(Chief Financial Officer)Alex Marshall(Chief Business Officer)in

Co-investorsEMBL VenturesGimvBoehringer Ingelheim Venture FundBioMedPartners

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

Harpoon Medical, Inc.AdorxAdoRx TherapeuticsCaldan TherapeuticsClyde BiosciencesEdinimageHarnessKodikaz Therapeutic SolutionsKynos TherapeuticsKynostxLario TherapeuticsMolecular ImagingNodTheraSIRAKOSSSyntheon 2.0

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

Exits · 5

5 acquisitions

CONFLUENCE LIFE SCIENCES, INC.acq. by Aclaris TherapeuticsHarpoon Medical, Inc.acq. by Edwards LifesciencesApellis Pharmaceuticalsacq. by BiogenKynos Therapeuticsacq. by Dr. Falk Pharma GmbHSIRAKOSSacq. by OssDsign

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has Epidarex Capital made?
Epidarex Capital has 41 tracked investments, 5 of which have exited, including 1 dated in the last 24 months.
What stage does Epidarex Capital invest at?
Epidarex Capital invests at the Seed, Series A stages.
What is Epidarex Capital's typical check size?
Epidarex Capital typically writes checks of $2.5M – $6.3M.
What sectors does Epidarex Capital focus on?
Epidarex Capital focuses on Biotech, Digital Health, Healthtech, Medical Devices.
Where is Epidarex Capital located?
Epidarex Capital is headquartered in Bethesda, US.
Does Epidarex Capital lead rounds?
Yes, Epidarex Capital leads investment rounds.
Who does Epidarex Capital co-invest with?
Epidarex Capital most often shares deals with BioGeneration Ventures, Broadview Ventures, F-Prime Capital, among 37 tracked co-investors.

Media · Podcasts & interviews

featuring the team

Dr Peter Finan, BIA Board Member, Partner, Epidarex Capital on SVB collapse

BioIndustry Association - BIA · Peter Finan

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