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5AM Ventures

Venture capital

Boston · Seed–Late Stage · 40 people tracked

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Investment thesis

5AM invests in diversified advanced life science technologies across biopharmaceutical, drug delivery, and research instrument sectors. The firm focuses on innovative platform technologies, corporate spin-offs, and products with shorter development cycles, with investments spanning multiple therapeutic areas within healthcare.

Invests inBiotechDigital HealthHealthtechMedical DevicesBostonMenlo ParkSan Francisco

Source: firm website, verified Jul 21, 2026.

Stage
Seed–Late Stage
HQ
Boston, US
Instruments
Equity
Founded
2002
AUM
$1.1B
Tracked investments
89

Team · 40 people

from the firm's website
Andy J. Schwab· Managing Partner
John D. Diekman· Founding Partner
Kush M Parmar· Managing Partner
Scott M. Rocklage· Founding Partner
Anna Yaeger· Chief Investment Officer and Partner
Deborah Palestrant· Partner, Executive Chair, 4:59 Initiative
John Kelly· Partner, Chief Financial Officer & Chief Operating Officer
Michael Calore· Partner, Head of Investor Relations
Katie Bodner Spielberg· Principal
Max Farina· Principal
Arthur Tzianabos· Venture Partner
Brian Daniels· Venture Partner
Elliott Levy· Venture Partner
Joe Loscalzo· Venture Advisor
Jonathan Weissman· Venture Advisor
Joseph J. Victor· Venture Advisor
Joshua Grass· Venture Partner
Mason Freeman· Venture Partner
Paula Soteropoulos· Venture Advisor
Peter S. Kim· Venture Advisor
Steve Hitchcock· Venture Partner
Vamsi Mootha· Venture Advisor
Alex Wareham· Management Company Controller
Aniqa Tasnim· Senior Associate
Bella Nittolo· Administrative Assistant and Office Manager
Britt Inga Emerson· Associate Director, Investor Relations
Caroline Chamales· Senior Executive Assistant
Jami Wiegand· Senior Manager, Information Technology
Jane Johnstone· Director, Legal
Jennifer Kozub· Operations Manager and Executive Assistant
Jennifer Zimmermann· Marketing Manager & Executive Assistant
Julia Jones· Senior Fund Accountant
Katie Wolfe· Executive Assistant
Kori Rahaim· Senior Vice President, Head of People and 4:59 Initiative Business Operations
Lauren Daniel· Chief Compliance Officer and General Counsel
Lidia Liu· Senior Research Analyst
Luke Serra· Assistant Controller
Paul A. Stone· Legal Advisor
Travis Fleming· Analyst
Zoë Rubin· Director of Compliance

What they invest in

from 4 of 89 portfolio companies

Biotech ×3AI & Machine Learning ×2Deep Tech ×2Digital Health ×1Enterprise Software ×1Healthtech ×1Medical Devices ×1SaaS ×1

HQs:United States×5

Investments · showing 60 of 89

founders shown can be your intro path
Lifordi Immunotherapeuticslifordi.com✓ verified

Lifordi Immunotherapeutics develops treatments for immunology and rare diseases through discovery, clinical development, and commercialization. The company serves patients with immunological disorders and rare genetic conditions.

BiotechDeep TechHealthtech

Arthur O. Tzianabos, Ph.D.(President and CEO)Naina Bhasin, Ph.D.(Chief Business Officer)

Precedeprecede.bio✓ verified

Precede Biosciences develops a blood-based diagnostic platform that profiles gene expression from cell-free DNA to reveal disease biology at the transcriptional level for drug developers and clinical trials. The platform enables non-invasive patient selection and longitudinal tracking of disease mechanisms in oncology and other therapeutic areas.

AI & Machine LearningBiotechDigital HealthBoston, US

Rehan Verjee(Co-Founder, Chief Executive Officer, Board Director)Sylvan Baca(Co-Founder; Assistant Professor of Medicine, Dana-Farber Cancer Institute)Toni Choueiri(Co-Founder; Director, Lank Center for GU Oncology, Dana-Farber Cancer Institute)Matthew Freedman(Co-Founder; Professor of Medicine, Dana-Farber Cancer Institute)

Achaogen
Akouos
Alexza
Ambrx
Aprea
Artiva Biotherapeutics
Arvinas
Audentes
Bellerophon
Biozbioz.com

Bioz provides AI-powered widgets for suppliers that display scientific publication data to build trust and improve sales conversion.

AI & Machine LearningEnterprise SoftwareSaaS

Bioz
Bird Rock Bio
Cabaletta Bio
Calibrium
Camp4
Cellular Research
Ceterix
Chrono
Cidara
CinCor
Crinetics
Deverra
Dianthus Therapeutics
DVS
Enliven Therapeutics
Ensoma
Entrada
Envoy
Epirus
Escient Pharmaceuticals
Expansion Therapeutics
Faraday
Flexion
GlycoEra
Halio, Inc.
Homology Medicines, Inc.
Ideaya Biosciences
Igenica
Ikaria
Ilypsa
Impel Neuropharma
Incline
Inipharm
KaloBios
Karius
Kinaset Therapeutics
Latigo
Lifordi
Magnetic Insight
Marcadia
Mendra
Miikana
Millendo
nChroma Bionchromabio.com

nChroma Bio develops in vivo targeted delivery and genetic engineering technologies for genetic medicine applications. The company works with academic founders and institutional investors focused on advancing gene therapy treatments.

BiotechDeep TechMedical Devices

Luke Gilbert, PhDKeith Joung, MD, PhDDavid Liu, PhDAngelo Lombardo, PhD

nChroma Bio
Neurogastrx
Nido Bio
NodThera

Board seats · per SEC filings · 4

what is this? ⓘ
Rallybio CorpSEC filing

$6.6M raise · filed Apr 2024 · via Kush M. Parmar, Paula M. Soteropoulos

Ensoma, Inc.SEC filing

$129M raise · filed May 2023 · via Kush M Parmar, Paula Soteropoulos

Entrada Therapeutics, Inc.SEC filing

$116.2M raise · filed Apr 2021 · via Kush M. Parmar

Purigen Biosystems, Inc.SEC filing

$34.4M raise · filed Apr 2021 · via Joseph J. Victor

Inferred from directors named on each company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

Frequently asked questions

What stage does 5AM Ventures invest at?
5AM Ventures invests at the Seed, Series A, Growth, Late Stage stages.
What sectors does 5AM Ventures focus on?
5AM Ventures focuses on Biotech, Digital Health, Healthtech, Medical Devices.
Where is 5AM Ventures located?
5AM Ventures is headquartered in Boston, US.

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