Catalio Capital Management, LP
Crossover fundNew York · Seed–Late Stage · 39 people tracked
Investment thesis
Catalio invests in innovative healthcare companies at all stages and sizes, spanning the full capital structure across private, public, and credit markets. The firm leverages a network of 45+ venture partners — world-renowned scientist-entrepreneurs — who provide proprietary deal flow, serve as an expert network for due diligence, advise on emerging and disruptive life sciences trends, and offer early exposure to breakthrough technologies. These partners contribute specialized scientific, technological, and clinical expertise and bring a track record of building companies that have generated significant enterprise value.
Source: firm website, verified Aug 11, 2026.
Team · 39 people
from public directoriesWhat they invest in
from 52 of 106 portfolio companiesBiotech ×37Healthtech ×28Medical Devices ×23AI & Machine Learning ×11Deep Tech ×9Digital Health ×8Longevity ×2Mental Health ×2
HQs:United States×40
Investments · 106 tracked
founders shown can be your intro pathBy year:2026 · 12025 · 12023 · 12022 · 22021 · 12020 · 12018 · 12016 · 12015 · 110 dated
Clinical-stage biopharmaceutical company focused on identifying, developing and commercializing differentiated medicines for cancer patients.
BiotechMedical DevicesNewtown Square, US
Brent Rice(Chief Commercial Officer)Jason Zhang(Director)Cong Xu(Director)Zhengbin (Bing) Yao(Executive Officer, Director)Stuart Lutzker(Director)
AtaiBeckley develops rapid-acting mental health treatments and therapies for patients with difficult-to-treat mental health conditions.
BiotechDeep TechDigital HealthMedical DevicesMental Health
Srinivas Rao(Co-Founder and Chief Executive Officer)Christian Angermayer(Founder and Chairman of the Board)
Avalyn Pharma develops a nebulized inhalation treatment for pulmonary fibrosis designed to improve tolerability compared to existing oral therapies by directly delivering the drug to the lungs.
BiotechMedical Devices
Lyn Baranowski(CEO)in
Fractyl develops therapies for obesity and type 2 diabetes, focusing on non-drug-based approaches rooted in understanding metabolic disease mechanisms.
BiotechHealthtechMedical DevicesLexington, US
ALLAN WILL(Director)STANLEY LAPIDUS(Director)NIMESH SHAH(Director)CHRISTOPHER GABRIELI(Director)HARITH RAJAGOPALAN(Executive Officer, Director)JAY CAPLAN(Executive Officer, Director)
Freenome develops early-stage cancer detection technology using blood tests to identify cancer in its earliest, most treatable phases.
AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesLondon
Riley Ennis(Co-Founder and Chief Product Officer)Stuart Lawson(Director)Charles Roberts(Director)Gabriel Otte(Director)
Neumora is a clinical research company developing investigational medications, with a focus on conducting clinical trials to obtain regulatory approval and make treatments available to patients.
BiotechDeep TechDigital HealthMedical DevicesWatertown, US
Matthew Fust(Director)Kari Stefansson(Director)Joshua Pinto(Executive Officer)Maykin Ho(Director)Alaa Halawa(Director)Tamara Tompkins(Executive Officer)
Helicons develops a peptide-based therapeutic platform designed to target intracellular proteins previously considered undruggable by combining the specificity of antibodies with the cell-penetrating properties of small molecules.
AI & Machine LearningBiotechDeep TechMedical Devices
Mathai Mammen(CEO, President and Chairman)
Abridge builds AI software that converts clinical conversations into structured insights for healthcare providers.
AI & Machine LearningDigital HealthHealthtechPhiladelphia, US
Shiv Rao(Founder & CEO)Julia Chapin(Executive Officer)Sagar Sanghvi(Executive Officer)
BoardAndy Weissman(Director)Sebastian Duesterhoeft(Director)Will Reed(Director)
AdvanCell develops radioisotope-based therapies, using Th-228 sourced through the U.S.
BiotechHealthtechMedical DevicesCambridge, US
Philina Lee(Executive Officer, Director)Aaron Pickett(Executive Officer)Wing Cheong Lam(Director)Nik Economopoulos(Director)Anthony Aiudi(Director)Jamil Beg(Director)
Amalgam develops a modular, AI-powered software-as-a-medical-device (SaMD) platform and EHR-integrated solutions for healthcare providers, health plans, and life sciences companies.
AI & Machine LearningDigital HealthHealthtechMedical DevicesWilmington, US
RYAN A. SYSKO(Executive Officer, Director)
BoardSONNY VU(Director)JEFFREY P. COURTNEY(Director)
BiotechRedwood City, US
Jeffrey Cleland(Manager of Company)Kannan Rangaramanujam(Manager of Company)Sujatha Kannan(Manager of Company)
BoardJustin Hanes(Manager of Company)
ATAI is developing rapid-acting, durable mental health treatments to address unmet needs in psychiatric conditions affecting over one billion people globally.
BiotechHealthtechMental Health
HealthtechNew York, US
Patrick Freuler(Executive Officer, Director)Andre Sequin(Executive Officer)
BiotechCambridge, US
Mohamed Genead(Executive Officer, Director)Michael Tolentino(Executive Officer, Director)David Callanan(Executive Officer)Tarek Hassan(Executive Officer)Derek Kunimoto(Executive Officer)
BoardDavid Guyer(Director)
HealthtechAuburndale, US
Samantha Pulliam(Executive Officer, Director)Vincent Ricci(Executive Officer)Jim O'Connor(Executive Officer)Shacey Petrovic(Executive Officer, Director)Eileen Maus(Executive Officer, Director)
BoardJonathan Dean(Director)
Bayesian Health develops clinical artificial intelligence for real-time patient monitoring and clinical decision support.
AI & Machine LearningDigital HealthHealthtechMedical Devices
Dr. Suchi Saria
Boston, US
Jacob A. Donoghue, M.D., Ph.D.(Executive Officer, Director)Jarrett Revels(Executive Officer)Jacob A. Donoghue(Executive Officer, Director, Promoter)
BoardCaitlin Donovan(Director)Pavel Raifeld(Director)Naveen Rao(Director)
Blackrock Neurotech develops a neurotechnology platform, including brain-computer interface systems, aimed at improving patient lives and treating neurological conditions.
BiotechDeep TechMedical Devices
Florian Solzbacher(Co-Founder & CSO)Marcus Gerhardt(Co-Founder & CEO)Thomas Thiele(CFO)Christian Angermayer(Co-Chairman)Tim Sievers(Co-Chairman)
Cambrian Bio is a clinical-stage biopharmaceutical company developing precision therapeutics targeting metabolic pathways associated with aging, including AMPK and mTOR.
BiotechLongevityMedical DevicesNew York, US
James G. Peyer(Executive Officer, Director)Juliette Han(Executive Officer, Director)Mark Nuttall(Executive Officer)Ruth Thieroff-Ekerdt(Executive Officer)William DeVaul(Executive Officer)Christian Angermeyer(Director)
Combines single-cell RNA analysis technology from the Broad Institute with AI/ML models and large-scale clinical sample collection for novel drug discovery and precision medicine.
HealthtechCambridge, US
Michael Boretti(Executive Officer)Tariq Kassum(Executive Officer, Director)Christoph Lengauer(Executive Officer, Director)
Centenara Labs is a longevity-focused drug discovery company that translates research on the biology of aging into therapies intended to improve healthy aging and extend lifespan.
BiotechHealthtechLongevity
Christian Angermayer(Founder)
Centrexion is a pharmaceutical company developing drugs in two therapeutic areas: non-opioid pain relief and immunology.
BiotechBaltimore, US
Sol Barer(Director)Kerrie L. Brady(Executive Officer)James N. Campbell(Executive Officer, Director)Shengda Zan(Director)Gregg Beloff(Executive Officer)Arnold L. Oronsky(Director)
BiotechJersey City, US
Cheng Zhang(Executive Officer, Director)
BoardVivek Garipalli(Director)Nick Olsen(Director)Peter DiLaura(Director)
Cresilon is a Brooklyn-based medical device company that develops plant-based hydrogel hemostatic products to rapidly stop bleeding.
BiotechHealthtechMedical DevicesBrooklyn, US
Isaac Miller(Co-founder)Joseph Landolina(Executive Officer, Director)Scott Levine(Executive Officer)Joe Landolina(Co-founder)
BiotechBrookline, US
Luhan Yang(President, Secretary and Treasurer)Geoff MacKay(Chief Executive Officer)
BoardGeorge M. Church(Director)
Boston, US
Georgiamune develops targeted immunomodulator drugs designed to regulate immune signaling pathways for treating cancer and autoimmune diseases.
BiotechHealthtech
Hippocratic AI develops generative AI agents designed for healthcare delivery, working with hospital systems, health plans, and life sciences companies to support clinical decision-making and patient care.
AI & Machine LearningDigital HealthHealthtech
Munjal Shah(Chief Executive Officer, Co-founder)inDr. Meenesh Bhimani(Chief Medical Officer, co-founder)inVishal Parikh(Chief Product Officer, Co-founder)inSubho Mukherjee(Chief Science Officer, Co-founder)in
Leo Cancer Care develops upright radiotherapy systems, including patient positioning, imaging, and treatment solutions for photon and particle (proton) therapy.
HardwareHealthtechMedical Devices
LifeSprout develops tissue-engineering products for aesthetic and regenerative medicine, designed to restore soft tissue losses caused by aging, cancer, and metabolic disease.
BiotechHealthtechMedical DevicesBaltimore, US
Hai-Quan Mao(Executive Officer, Promoter)Sashank Reddy(Executive Officer, Director, Promoter)Gregory Sieczkiewicz(Executive Officer, Director, Promoter)
Exits · 11
IPOs and acquisitions across the tracked portfolioArriVent BioPharmaNASDAQ: AVBPAtaiBeckleyNASDAQ: ATAIAvalyn Pharma IncNASDAQ: AVLNCompass PathwaysNASDAQ: CMPSFractylNASDAQ: GUTSFreenomeNASDAQ: FRNMKardiganNASDAQ: KARDNeumora TherapeuticsNASDAQ: NMRAParabilis MedicinesNASDAQ: PBLSProtara TherapeuticsNASDAQ: TARACelsius Therapeuticsacq. by AbbVie
Portfolio news
latest coverage across their companiesAdvanCell · intelligence360.news · Aug 4, 2026
Oncusp Therapeutics · techcrunch.com · Jul 30, 2026
NextPoint Therapeutics · nature.com · Jul 22, 2026
Resilience · tectonicdefense.com · Jul 17, 2026
AtaiBeckley · stocktitan.net · Jul 17, 2026
Neumora Therapeutics · dailypolitical.com · Jul 16, 2026
Fractyl · investing.com · Jul 15, 2026
Immunai · thenextweb.com · Jul 15, 2026
Frequently asked questions
- What stage does Catalio Capital Management, LP invest at?
- Catalio Capital Management, LP invests at the Seed, Series A, Series B, Series C, Growth, Late Stage stages.
- What sectors does Catalio Capital Management, LP focus on?
- Catalio Capital Management, LP focuses on Biotech, Digital Health, Healthtech, Longevity, Medical Devices.
- Where is Catalio Capital Management, LP located?
- Catalio Capital Management, LP is headquartered in New York, US.
- Does Catalio Capital Management, LP lead rounds?
- Catalio Capital Management, LP typically participates in rounds rather than leading them.
Images
Co-investors · 12
ARCH Venture Partners is a venture capital firm that backs and helps build transformational companies, with a strong focus on the life sciences and biotech sector.
Andreessen Horowitz's Strategic Partnerships page describes collaborations that connect its portfolio companies with established institutions to help scale and deploy their technology.
Vivo Capital is a global healthcare-focused investment firm operating a multi-strategy platform spanning venture capital, private equity, and public equity. It aims to expand healthcare access and drive innovation through its 'Ecosystem Strategy.'
Sequoia Capital is a venture capital firm that partners with founders to build technology companies, with a strong current focus on artificial intelligence.
Alumni Ventures (AV) is a venture firm that gives accredited individual investors access to professionally managed, diversified venture portfolios by co-investing alongside leading lead VC firms. It offers annual funds, syndicate deal-by-deal investing, and various investor clubs.
Polaris Partners is a venture capital firm that partners with biotech and healthcare entrepreneurs to build transformational companies.
MPM BioImpact combines 30+ years of biotech venture capital expertise with impact investing and public market experience, managing early-stage venture funds, private/public impact funds, and a public equities fund focused on transforming patient outcomes.
Third Rock Ventures is a venture capital firm that discovers, launches, and builds life sciences and biotechnology companies developing novel medicines and therapies.
Abingworth is a life science venture capital firm that backs early-stage biopharma and biotech companies, helping entrepreneurs translate scientific discoveries into new therapeutics.
Hatteras Venture Partners is a venture capital firm focused on early-stage life sciences and healthcare companies, backing therapeutics, diagnostics, and businesses aiming to transform healthcare delivery and innovation.
Nexus Venture Partners invests in early and early growth stage companies operating in India and the United States across multiple sectors. The firm was founded by entrepreneurs with experience building companies.
Catalio is a software platform that uses AI to automatically extract and document business logic from legacy and modern systems, creating living specifications that stay current as software evolves.
Firms observed investing alongside Catalio Capital Management, LP, from public investor directories. Shared companies are the overlap with Catalio Capital Management, LP's recorded portfolio.
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