Breakout Ventures
Actively deployingSan Francisco · Seed–Series B
Fund manager profile
Breakout Ventures is a venture fund manager based in San Francisco. SEC filings show 2 venture funds on record, most recently Breakout Ventures III-B, L.P. ($12.1M offering) filed March 2026.
Source: SEC EDGAR Form D filings. Firm website data not yet available.
What they invest in
from 8 of 27 portfolio companiesBiotech ×6AI & Machine Learning ×4Deep Tech ×4Healthtech ×3Cleantech ×2Climate Tech ×2Digital Health ×2Medical Devices ×2
HQs:United States×5
Investments · 27 tracked
founders shown can be your intro pathA-Alpha Bio uses synthetic biology and machine learning to measure, predict, and engineer protein-protein interactions for pharmaceutical discovery and development. The company operates experimental (AlphaSeq) and computational (AlphaBind) platforms to accelerate the design of novel therapeutics.
AI & Machine LearningBiotechDeep TechSeattle, US
David Younger, PhD(Chief Executive Officer & Co-Founder)Randolph Lopez, PhD(Chief Technology Officer & Co-Founder)
CellChorus develops a visual AI platform called TIMING that performs high-throughput dynamic analysis of single cells, measuring cell activation, killing, and movement over time for biopharmaceutical research. The company serves biopharmaceutical companies and therapy developers seeking to understand cellular function and phenotype.
AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesHouston, US
Navin Varadarajan(Co-founder)inLaurence Cooper(Co-founder & Board Chair)Daniel Meyer(Chief Executive Officer)Rebecca Berdeaux(Chief Scientific Officer)
Copernic develops catalysts for zero-carbon ammonia and e-fuels that are cost-competitive and compatible with existing industrial infrastructure. The company uses scientific computing to improve heterogeneous catalyst design for the chemical industry.
CleantechClimate TechDeep Tech
Epana Bio develops therapies for autoimmune diseases by leveraging genomics and AI to identify and target cellular origins of disease, with a focus on precision medicine for patient populations.
AI & Machine LearningBiotechDigital Health
Modern Meadow develops animal-free, bio-fabricated leather alternatives using synthetic biology and material science for the fashion, interiors, and automotive industries. Its flagship product, INNOVERA™, is engineered from plant-based proteins, biopolymers, and recycled materials to replicate leather performance while maintaining high renewable carbon content.
BiotechCircular EconomyNew MaterialsPine Brook, US
Parallel Bio develops human immune organoids and computational tools to predict drug efficacy across diverse patient populations, replacing animal testing in drug discovery. The company aims to accelerate pharmaceutical development and reduce clinical trial failure rates through human-first biological prediction models.
AI & Machine LearningBiotechDeep TechHealthtechSan Francisco, US
Robert DiFazio(Founder)inJuliana Hilliard(Founder)inRobertJuliana
Cytovale develops microfluidic deformability cytometry technology for immune response diagnostics, with a focus on early detection and diagnosis in hospital settings. The company serves healthcare systems and clinicians with diagnostic instruments and solutions.
BiotechDigital HealthHealthtechMedical Devices
Ajay Shah(Co-founder & CEO)Henry Tse(Co-founder & Chief Technology Officer)
Frequently asked questions
- What stage does Breakout Ventures invest at?
- Breakout Ventures invests at the Seed, Series A, Series B stages.
- Where is Breakout Ventures located?
- Breakout Ventures is headquartered in San Francisco, US.
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