Connecticut Innovations
Corporate VCConnecticut · Pre-Seed–Growth · 1 people tracked
Investment thesis
Connecticut Innovations focuses on supporting companies from product launch through scaling, offering capital, operational guidance, and connections to strategic talent and world-class investors. The firm prioritizes helping startups build management teams, raise capital, and ultimately grow into successful businesses that create lasting impact and jobs in Connecticut.
Source: firm website, verified Jul 21, 2026.
Team · 1 people
from the firm's websiteMatthew McCooe is the Chief Executive Officer of Connecticut Innovations, leading venture capital funds, loans and programs with over 25 years of experience in venture capital investing and product management. His prior roles include managing director at Columbia University Science and Technology Ventures, founding Eureka Networks (sold for $110M), and senior positions at Chart Venture Partners and Fortune 500 companies Becton Dickinson and MCI.
What they invest in
from 161 of 196 portfolio companiesAI & Machine Learning ×40Biotech ×40Medical Devices ×35Healthtech ×34Enterprise Software ×25SaaS ×22Consumer ×19Digital Health ×17
HQs:United States×33Israel×3Canada×1India×1Netherlands×1
Investments · showing 60 of 196
founders shown can be your intro pathAeromics is a clinical-stage biopharmaceutical company developing AER-271, an aquaporin-4 inhibitor to prevent cerebral edema (brain swelling) in severe acute ischemic stroke patients. The therapy targets molecular water channels to improve survival and recovery outcomes while reducing the need for invasive surgical interventions.
BiotechMedical DevicesNew Haven, US
Dr. Pelletier(Founder)Dr. Boron(Founder)
NourishedRx provides a data-driven nutrition care platform that connects health plans, providers, and government agencies with clinically guided meal plans and health coaching to address chronic diseases and nutrition insecurity. The company delivers evidence-based food and wellness interventions coordinated by registered dietitians and health coaches to improve population health outcomes.
Digital HealthFoodTechHealthtech
OmniCyte develops targeted immunotherapy treatments for cancer patients using a proprietary immuno-oncology platform technology, with initial focus on ovarian cancer and small cell lung cancer.
BiotechMedical DevicesNew York, US
Yuma powers decentralized AI projects built on the Bittensor network, connecting entrepreneurs and developers with resources to build and launch subnets. The platform serves builders focused on areas including computer vision, bandwidth aggregation, AI safety, code security, and synthetic identity generation.
AI & Machine LearningCrypto & Web3Deep Tech
Greg SchveyJeff Schvey
AbbraTech develops a platform technology for discovering and validating antibody therapies targeting disease. The platform enables antibody discovery against drug targets previously inaccessible through conventional methods, particularly for cancer, immune disorders, and viral infections.
BiotechBranford, US
Aceiss detects unauthorized employee access to company systems and monitors user privileges across applications to prevent cyber attacks. It provides visibility and analytics for access control, compliance audits, and zero trust security implementation.
CybersecurityDeveloper ToolsEnterprise Software
Adaptive provides specialty insurance and climate-resilient coverage solutions powered by proprietary data models and advanced technology. The company serves residential customers, commercial businesses, agents, and insurance partners with products like parametric power outage insurance and wind/hail deductible buy-backs.
Climate TechInsurTech
AmpUp develops electric vehicle charging infrastructure solutions for drivers, businesses, and communities. The company builds dependable and accessible charging systems to expand EV adoption and mobility.
Climate TechConsumerEnergyMobility & TransportationSaaSSan Francisco, US
Thomas Sun(Founder)in
Apriligen develops autologous gene therapies for pediatric monogenic diseases, starting with Diamond Blackfan Anemia Syndrome. The company uses lentiviral technology to correct genetic defects by modifying patients' own cells, aiming to provide curative alternatives to traditional transplants.
BiotechHealthtechMedical Devices
Arccos is an AI-powered golf performance analytics platform that tracks player shots and game metrics across 1.5 billion rounds to provide personalized insights and strategy recommendations. The platform serves golfers of all skill levels through hardware and software products including sensors, wearables, and laser rangefinders.
AI & Machine LearningHardwareSports Tech
Arvinas is a clinical-stage biopharmaceutical company developing PROTAC protein degrader therapies for oncology and neurology. The company focuses on discovering and developing novel investigational drugs for patients with limited or ineffective treatment options.
Biotech
Asarasi produces sparkling water made from maple tree sap, sourced sustainably from living trees as a renewable alternative to groundwater-based bottled water. The company serves environmentally conscious consumers and supports maple farming operations.
CleantechConsumerFoodTech
Athletic Brewing produces craft non-alcoholic beer in multiple styles including IPAs, pale ales, radlers, and sours for consumers seeking flavorful beverages without alcohol. The company markets itself as the #1 selling craft non-alcoholic beer brand and holds B-corp certification.
ConsumerFoodTech
Secure Bags provides bookkeeping, accounting, and CFO reporting services combined with funding facilitation for small businesses. The platform integrates with QuickBooks, delivers monthly financial reports, and connects businesses with over 60 lenders to support growth.
AI & Machine LearningFintechSaaS
BEKhealth provides AI-powered clinical intelligence software that extracts data from electronic health records to enable faster clinical trial recruitment and real-world evidence generation. The platform serves sponsors, contract research organizations (CROs), research site networks, and healthcare organizations seeking to identify eligible patients and leverage clinical data for research.
AI & Machine LearningDigital HealthHealthtech
Better Rhodes is a marketplace for non-alcoholic beverages, offering premium alcohol-free wines and craft NA beers through monthly subscription clubs. The platform serves consumers interested in mindful drinking alternatives.
ConsumerE-commerceMarketplaces
Bexorg is a biotech platform for CNS drug discovery built on a whole-brain perfusion model that allows manipulation and recording of cellular activity in intact human brains. The company serves pharmaceutical researchers developing treatments for brain diseases.
AI & Machine LearningBiotechDigital HealthMedical DevicesNew Haven, US
Zvonimir VrseljaNenad Sestan
Biohaven is a biopharmaceutical company focused on discovering and developing treatments in immunology, obesity, neuroscience, and oncology, including approved migraine medications. The company advances therapeutic programs for diseases with significant unmet medical needs.
BiotechHealthtechMedical Devices
BiologicsMD develops recombinant fusion proteins targeting parathyroid hormone receptors for hair loss, bone disorders, and oncology treatments. The company's technology uses a dual-domain approach to localize therapeutics to disease sites with minimal off-target effects.
BiotechDeep TechMedical Devices
BioWave develops a wearable neurostimulation device that delivers high-frequency electrical stimulation directly to nerves to block pain signals, marketed as a treatment for chronic pain conditions without requiring continuous use.
HealthtechMedical Devices
Bloom provides credit data infrastructure and underwriting technology for financial institutions, fintechs, and credit unions to make lending decisions and build credit. The platform offers consumer credit data validation, Metro2 bureau reporting, dispute management, and tools to enable inclusive lending decisions.
Data & InfrastructureFintech
Bright Feeds develops technology to transform unwanted food into animal feed, helping food companies meet sustainability goals while reducing waste. The company operates in food manufacturing and circular economy by-products.
Circular EconomyFoodTech
Budderfly provides energy management services for businesses, upgrading operational infrastructure with energy-efficient equipment and monitoring systems to reduce energy consumption by up to 30%, operating on a performance-based model where the company is paid from the savings generated.
CleantechEnterprise SoftwareIoT
Al Subbloie(Founder and CEO)
Bullish is a creative agency offering consulting and capital services, positioning itself as focused on consumer insights and market strategy.
Consumer
C2 Ventures is a venture capital firm that invests in AI-powered software solutions for industries with high-risk, repetitive, or hazardous work. The firm focuses on companies that integrate AI as a feature within SaaS platforms to solve specific business problems in these verticals.
AI & Machine LearningEnterprise SoftwareSaaS
Cambium develops technology and marketplace infrastructure for the wood industry, connecting buyers and sellers while offering sustainably sourced wood products made from waste material. The company serves traditional wood industry participants with digital tools to improve transparency and sustainability across the supply chain.
B2B MarketplacesClimate TechLogistics & Supply ChainNew MaterialsCalifornia, US
Canotera provides an AI-powered platform that forecasts insurance claim outcomes, costs, and timelines by analyzing claim documents and comparing cases against historical precedents. The platform helps insurers optimize reserve allocation and case resolution strategies for claims management.
AI & Machine LearningInsurTech
Cape Haven Bio is a venture creation firm focused on translating early-stage academic discoveries into commercially viable biotech companies developing therapeutics. The firm provides strategic planning, lab infrastructure, seed capital, and consulting resources to support the progression from research to investable business.
BiotechDeep TechNew Haven, US
Carbon Built produces ultra-low carbon concrete masonry and hardscapes for construction projects by substituting conventional cement with a proprietary upcycled binder, achieving up to 70% reduction in carbon footprint. The company serves builders and construction firms seeking lower-emission building materials.
CleantechClimate TechConstruction Tech
CaroGen develops immunotherapies for cancer treatment, including the CARG-2020 platform for ovarian and colorectal cancer, and is partnering with the NIH on a universal influenza vaccine.
BiotechHealthtechFarmington, US
CellsBin develops an AI-driven photonic semiconductor platform for detecting, isolating, and characterizing rare cells in biological samples for therapeutic monitoring and precision medicine applications. The company serves researchers and clinicians in drug development, cell therapy monitoring, and clinical diagnostics.
AI & Machine LearningBiotechMedical Devices
CiDRA provides SMARThatch, a real-time measurement system for ready-mix concrete trucks that monitors air content, volume, temperature, and other parameters via acoustic technology. The platform is designed for concrete producers and ready-mix companies to reduce waste, improve quality control, and optimize fleet operations.
Advanced ManufacturingConstruction TechIoT
CiDRA Minerals Processing develops mineral separation and processing technologies for mining operations, including SonarTrac and CycloneTrac solutions that improve mill grinding efficiency and flowsheet design.
AgTech
Cleancult produces cleaning products in recyclable, paper-based refillable bottles with transparent, non-toxic formulas. The company targets consumers seeking sustainable household cleaners as an alternative to conventional plastic-packaged products.
Circular EconomyCleantechConsumer
Ryan
Cloud9 Online develops medical-grade meditation technology that combines mindfulness with machine learning and mobile apps. The company licenses its MediGrade meditations to medical providers and employers seeking clinical-grade mindfulness solutions for their users, with data analytics linked to wellness outcomes and institutional KPIs.
AI & Machine LearningDigital HealthWellness & FitnessHartford, US
Coheso is an AI-powered legal intake platform that consolidates legal requests from email, Teams, and Slack into a single queue, automating routine legal questions and triaging complex matters for attorney review. The platform serves in-house legal teams at regulated and high-growth companies by reducing response times and attorney workload through AI-powered self-service and intelligent routing.
AI & Machine LearningEnterprise SoftwareLegalTech
Ned Gannon(CEO)
Coinbax provides a control layer for stablecoin and tokenized deposit payments, enabling banks and financial institutions to settle transactions instantly while maintaining institutional-grade approvals, limits, and reversibility. The platform integrates with existing banking infrastructure to add compliance, fraud detection, and multi-party approval workflows to blockchain-based payments.
Crypto & Web3Enterprise SoftwareFintech
Corechain provides a B2B payments platform that streamlines paperless payments and supply chain financing to help suppliers unlock working capital from unpaid invoices.
Enterprise SoftwareFintechSaaS
Corisma develops a fully implanted transcatheter mechanical circulatory support system for advanced heart failure patients, designed to bridge acute and chronic care with improved quality of life. The device eliminates the driveline and uses wireless, catheter-based technology to replace current standard-of-care treatment options.
Deep TechHealthtechMedical Devices
R. William Vogel(Chief Executive Officer)Kaushik Mandal(Chairman)
CREW provides process intensification technology for wastewater treatment facilities using calcium carbonate dosing to enhance treatment efficiency, reduce operating costs, and remove greenhouse gases. The solution integrates into existing infrastructure and generates verified carbon removal credits for buyers.
Circular EconomyCleantechClimate TechNew Haven, US
Curacity VISTA helps hotels, resorts, cruise lines, and destinations drive bookings through editorial media placements that increase visibility in AI-powered travel recommendation systems. The platform leverages AI and editorial content strategy to capture higher-margin demand from travelers who discover properties through trusted media outlets and generative AI.
AI & Machine LearningMarketing TechTravel & Hospitality
Cybrexa Therapeutics develops a tumor-targeting platform called alphalex that enables targeted delivery of anticancer drugs directly to tumor cells independent of surface antigens. The company focuses on oncology and aims to provide new treatment options for cancer patients.
BiotechMedical Devices
D-ID develops an AI video creation platform that produces professional avatar videos and interactive visual agents for enterprise communication and customer experience. The platform serves organizations across industries for training, marketing, customer support, and brand messaging.
AI & Machine LearningCybersecurityEnterprise SoftwareMarketing TechSaaSTel Aviv-Yafo, IL
Sella Blondheim(Founder)inEliran Kuta(Founder/CTO)inOfer Ben-NoonNot specified on this page
D2B3 develops proprietary drug delivery technology that temporarily relaxes the blood-brain barrier to enable therapeutic targeting of central nervous system diseases. The platform is designed to work across multiple drug classes for treating brain-related disorders.
BiotechDeep TechMedical DevicesNew Haven, US
Davra provides an IoT platform designed for equipment manufacturers to develop and deploy connected device solutions with multi-vendor support, AI capabilities, and enterprise-grade security.
Advanced ManufacturingEnterprise SoftwareIoT
DebtWise provides debt management tools and products for financial institutions, universities, and fintech platforms to help consumers understand loans, manage payments, and build budgets. The company serves $260 million in loans across its customer base.
Fintech
Direct Color Systems manufactures industrial-grade negative pressure ink delivery systems for printers. The company serves print operations and offers technology designed to enable smaller-format printers to perform with capabilities comparable to larger industrial equipment.
Advanced ManufacturingHardware
Dream Payments provides embedded payment APIs and in-context payment solutions enabling banks, insurers, and software platforms to integrate inbound and outbound payment capabilities directly into customer workflows.
FintechSaaS
Driver Technologies develops dash cam software and hardware products for vehicle drivers. The company provides mobile app and accessory support for daily driving safety and recording.
HardwareIoT
Frequently asked questions
- What stage does Connecticut Innovations invest at?
- Connecticut Innovations invests at the Pre-Seed, Seed, Series A, Series B, Growth stages.
- What sectors does Connecticut Innovations focus on?
- Connecticut Innovations focuses on AI & Machine Learning, Biotech, Climate Tech, Consumer, IoT, Quantum Computing, Sector Agnostic.
- Where is Connecticut Innovations located?
- Connecticut Innovations is headquartered in Connecticut, US.
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