/Investor DB

OrbiMed

Crossover fundoperating company · company profile

New York · Seed–Late Stage · 92 people tracked

Also known as ORBIMED ADVISORS LLC

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Investment thesis

OrbiMed invests globally across the entire healthcare industry, from early-stage private companies to large multinational corporations. Its focus spans biopharmaceuticals, medical devices, digital health, diagnostics, and healthcare services, targeting innovations that improve patient outcomes and address unmet medical needs. With over 25 years of investing experience, the firm deploys capital across both public and private markets worldwide, backed by a team of scientific, medical, and investment professionals. The firm aims to support companies driving healthcare innovation and helping humanity live healthier, longer, and more productive lives.

Source: firm website, verified Sep 29, 2026.

Stage
Seed–Late Stage
Check
$1M – $75M
HQ
New York, NY, US
Leads rounds
Leads
Instruments
Equity · Debt
Founded
1989
Last 12 months
13 investments
AUM
$20.6B
Tracked investments
338
Unicorns
11
IPOs
51
Acquisitions
12

Team · 92 people

from the firm's website & curated & public directories
Sunny Sharma· Partnerin

Partner at OrbiMed holding an M.D.

Dimitri Krainc· Venture Partnerin
Bill Moschella· Venture Partnerin
Michael Eggenberg· Partnerin
Anat Nursella· Venture Partnerin
Brendan Weber· Principalin
Lars Enstrom· Managing Directorin
William Price· Managing Directorin

14 people who came through OrbiMed went on to found or lead other companies.

+ 2 more →

What they invest in

from 279 of 338 portfolio companies

Biotech ×213Healthtech ×179Medical Devices ×91Digital Health ×48AI & Machine Learning ×38Deep Tech ×28Hardware ×17Advanced Manufacturing ×10

HQs:United States×182China×11India×11Switzerland×3United Kingdom×3Australia×1

Who they back

founder profiles across 101 portfolio companies
40%
solo founders
40 of 101 mapped founding teams
26%
repeat founders
of 85 founders with career history
~4 yrs
old at investment
median across 64 dated deals

Founding team size:solo founder×402 founders×343 founders×154+ founders×12

Where their founders studiedfrom 78 founders with education data

Massachusetts Institute of Technology ×5Stanford University ×4Harvard Medical School ×3MIT Sloan School of Management ×3Princeton University ×3Stanford University School of Medicine ×3University of California, Berkeley ×3Ben-Gurion University of the Negev ×2

What their founders studiedfrom 81 founders with field-of-study data

Life Sciences ×27Medicine ×20Engineering ×15Chemistry ×13Business & Management ×12Computer Science ×8Finance & Accounting ×4Physics ×3

Where their founders worked beforefrom 85 founders with career history

Stanford University ×4Atlas Venture ×3Dana-Farber Cancer Institute ×3Harvard Medical School ×3Aisling Capital ×2ARCH Venture Partners ×2GlaxoSmithKline ×2M.D.G Medical Ltd. ×2

Accelerator rootsportfolio companies that came through a program

Y Combinator ×2

46 founders hold a PhD · 12 hold an MBA (of 87 with degree data) · backed the same founder in 2+ companies: 4 founders

Investments · 338 tracked

founders shown can be your intro path

By year:2026 · 102025 · 252024 · 122023 · 92022 · 82021 · 212020 · 112019 · 162018 · 92017 · 72016 · 92015 · 12161 dated

Q32 Bioq32bio.comin𝕏NASDAQ: QTTBSeries A · May 2020 · $46M✓ verified

Q32 Bio is a biotechnology company developing therapies for autoimmune and inflammatory diseases, with a scientific focus on the complement system and immune regulation in conditions such as inflammation, autoimmunity and fibrosis.

BiotechHealthtech

Shelia Violette(Founder & Chief Scientific Officer)inMichael Holers(Co-founder)Jodie Morrison(Chief Executive Officer)inLee Kalowski(President & Chief Financial Officer)Maria Marzilli(Chief Business Officer)inDavid Appugliese(Senior Vice President, Head of People)in

Co-investorsAtlas VentureAgent CapitalCU Healthcare Innovation FundOUP (Osage University Partners)Sanofi Ventures5AM Ventures+2 more

Scribe Therapeuticsscribetx.comin𝕏NASDAQ: SCTXMar 2021✓ verified

Scribe is a molecular engineering company developing CRISPR-based genetic therapies to treat cardiometabolic disease and other conditions.

BiotechDeep TechHealthtechMedical DevicesBerkeley, US

Benjamin Oakes(Founder)inJennifer A. Doudna, PhD(Co-founder, Scientific Advisor)Benjamin L. Oakes, PhD(Co-founder, President and CEO)David F. Savage, PhD(Co-founder, Scientific Advisor)Brett Staahl, PhD(Co-founder, VP of External Innovation)Brett Staahl(Founder)

Co-investorsAndreessen HorowitzAvoro Capital AdvisorsMenlo VenturesRA CapitalWellington Management

Sionna Therapeuticssionnatx.comin𝕏NASDAQ: SIONSeries B · Apr 2022 · $110M✓ verified

Sionna Therapeutics is a biopharmaceutical company founded in 2019 that develops small-molecule therapies for cystic fibrosis by targeting and stabilizing NBD1, the domain of the CFTR protein where the common ΔF508 mutation occurs.

BiotechHealthtechMedical Devices

Greg(Co-founder & Senior Vice President of Discovery Research)Mark(Co-founder & Senior Vice President of Medicinal Chemistry)Mike(President & CEO)Charlotte(Chief Medical Officer)Elena(Chief Financial Officer)Caroline(Chief Business Officer)

Co-investorsAtlas VentureRA CapitalViking Global

Upstream Bioupstreambio.comin𝕏NASDAQ: UPB✓ verified

Upstream Bio is a biotechnology company that sponsors clinical trials to develop products under investigation.

BiotechHealthtechWaltham, US

Rand Sutherland(Chief Executive Officer)inAllison Ambrose(General Counsel)inAaron Deykin(Chief Medical Officer & Head of R&D)inMike Gray(Chief Financial Officer and Chief Operating Officer)Adam Houghton(Chief Business Officer)inStacy Price(Chief Technology Officer)in

Co-investorsAccess IndustriesAccess BiotechnologyBain Capital Life SciencesDecheng CapitalHBM Healthcare InvestmentsHBM Partners+5 more

Aadi Bioscienceaadibio.cominNASDAQ: WHWKMar 2017SEC filingmedium confidence

Aadi Bioscience develops therapies targeting mTOR-driven diseases using precision medicine and albumin-bound nanoparticle technology, applying genomic profiling to identify patients most likely to benefit from mTOR inhibition.

BiotechHealthtechMorristown, US

Scott Giacobello(Executive Officer)inBryan Ball(Executive Officer)Dave Lennon(Executive Officer, Director)inDavid Dornan(Executive Officer)James Murphy(Executive Officer)Stephen Pakola(Executive Officer)

Board seatChau Khuong· per SEC Form D · $41.8M raise · filed Mar 2017

Co-investors3B Future Health FundAlly Bridge GroupDecheng CapitalVivo Capital

Adicet Bioadicetbio.comNASDAQ: ACETAug 2015

Adicet Bio develops allogeneic gamma delta CAR T cell therapies for patients with autoimmune diseases and cancer.

BiotechHealthtechMenlo Park, US

Aya Jakobovits(Executive Officer, Director)Nathan Hubbard(Executive Officer)inChen Schor(President, Chief Executive Officer and Director)in

BoardCarl Gordon(Director)inFlorent Gros(Director)

Board seatJonathan SilversteinCarl L. Gordon· per SEC Form D

Co-investorsForesite CapitalPontifax Venture CapitalQuan CapitalaMoonNovartis Venture FundPureTech Health

Arvinas Holding Co. LLCarvinas.comin𝕏NASDAQ: ARVNOct 2015SEC filingmedium confidence

Arvinas is a biopharmaceutical company developing PROTAC protein degrader therapies, with a pipeline focused on oncology and neurology.

BiotechHealthtechNew Haven, US

Sean Cassidy(Executive Officer)inManuel Litchman(Executive Officer, Director)inRandy Teel(President and Chief Executive Officer; Director)inCraig Crews(Founder)

BoardLiam Ratcliffe(Director)in

Board seatStephen Squinto· per SEC Form D · $55M raise · filed Apr 2018

Co-investors5AM VenturesAccess BiotechnologyCanaan PartnersConnecticut InnovationsNextech InvestRA Capital+2 more

Calcimedicacalcimedica.comin𝕏NASDAQ: CALCJul 2019

CalciMedica is a clinical-stage biopharmaceutical company developing CRAC (calcium release-activated calcium) channel inhibition therapies for serious acute and chronic inflammatory, immunologic, and cardiopulmonary diseases.

BiotechHealthtechLa Jolla, US

Kenneth A. Stauderman(Co-founder)inGonul Velicelebi(Co-founder)Daniel Geffken(Executive Officer)A. Rachel Leheny(Executive Officer, Director)Michael J. Dunn(Executive Officer)inStephen Bardin(Chief Financial Officer)in

Board seatChau Khuong· per SEC Form D

Co-investorsAisling CapitalMESA VERDE VENTURE PARTNERSRevelation PartnersSanderling VenturesClarus Ventures

Compass Therapeuticscompasstherapeutics.comin𝕏NASDAQ: CMPXJun 2020

Compass Therapeutics uses proprietary antibody discovery platforms to generate and screen diverse panels of monoclonal and multispecific antibodies, aiming to identify synergistic therapeutic combinations.

BiotechHealthtechCambridge, US

Schuetz Thomas(Executive Officer, Director)inErrik Anderson(Executive Officer, Director)inThomas J. Schuetz(Executive Officer, Director)inVered Bisker-Leib(Executive Officer)inBarry Shin(Chief Financial Officer)inNeil Lerner(Senior Vice President, Chief Accounting Officer)in

Board seatStephen SquintoCarl L. Gordon· per SEC Form D

Co-investorsAlumni VenturesBioBritF-Prime CapitalForesite CapitalGV (Google Ventures)venBio Partners+3 more

ImaraNASDAQ: ELVNSeries B · Mar 2019 · $63Macquired by Enliven Therapeutics · Feb 2023

Imara is a clinical-stage biopharmaceutical company developing small molecule therapeutics for unmet medical needs, currently advancing ELVN-001, a selective kinase inhibitor designed to treat chronic myeloid leukemia by targeting the BCR-ABL gene fusion.

BiotechCambridge, US

James G. McArthur(Executive Officer, Director)Christoph M. Adams(Executive Officer, Director)Richard Fair(President, Chief Executive Officer, Director)

BoardSara Nayeem(Director)Barbara Dalton(Director)David Mott(Director)

Board seatDavid Bonita· per SEC Form D

Co-investorsBay City CapitalNew Enterprise Associates (NEA)Pfizer Venture InvestmentsRA CapitalAlexandriaArix Bioscience+3 more

Keros Therapeuticskerostx.cominNASDAQ: KROSMar 2020

Keros is a clinical-stage biopharmaceutical company developing product candidates that modulate signaling of the transforming growth factor-beta (TGF-β) family of proteins to treat disorders affecting blood cells and tissues such as bone, muscle, adipose and heart.

BiotechHealthtechLexington, US

Jasbir Seehra(Co-Founder, Chief Executive Officer and Director)in

BoardJulius Knowles(Director)Alon Lazarus(Director)inOhad Hammer(Director)Ran Nussbaum(Director)in

Board seatCarl L. Gordon· per SEC Form D

Co-investorsArkin CapitalForesite CapitalPontifax Venture Capital

Mirna Therapeuticsblogmedicina.com𝕏OTC: SYBXJun 2019SEC filingmedium confidence

A Spanish-language blog that publishes articles on health and medicine topics, such as flu prevention and vaccination recommendations, for general readers.

BiotechMedia & EntertainmentAustin, US

Matthew Winkler(Director)Sinil Kim(Executive Officer)inPaul Lammers(Executive Officer, Director)inJon Irvin(Executive Officer)Casi DeYoung(Executive Officer)

BoardMichael Powell(Director)

Board seatChau Khuong· per SEC Form D · $80M raise · filed Jun 2019

Co-investorsNew Enterprise Associates (NEA)Pfizer Venture InvestmentsCorrelation VenturesOUP (Osage University Partners)Pfizer VenturesSofinnova Ventures

NextCurenextcure.comNASDAQ: NXTCDec 2015

Nextcure is a clinical-stage biopharmaceutical company developing immunotherapies targeting IO pathways, with a focus on oncology applications.

BiotechBeltsville, US

Michael Richman(Executive Officer, Director)Timothy Mayer(Executive Officer)inUdayan Guha(Executive Officer)inSteven P. Cobourn(Executive Officer)inSourav Kundu(Executive Officer)inKevin Shaw(Executive Officer)in

Board seatChau Khuong· per SEC Form D

Co-investorsBay City CapitalCanaan PartnersLAVLilly Asia VenturesPfizer Venture InvestmentsQuan Capital+4 more

Prelude Therapeuticspreludetx.comin𝕏NASDAQ: PRLDJun 2016

Prelude Therapeutics is a precision oncology company developing cancer treatments for areas of high unmet need, with a pipeline including selective KAT6A degraders and mutant-selective JAK2V617F JH2 inhibitors.

BiotechHealthtechNewark, US

Krishna Vaddi(Executive Officer, Director)

BoardPaul Friedman(Director of Issuer)

Board seatDavid Bonita· per SEC Form D

Co-investorsThe Innovation Space

SI-BONEsi-bone.comNASDAQ: SIBNJun 2016SEC filingmedium confidence

SI-BONE develops medical devices for treating sacroiliac (SI) joint dysfunction and chronic low back pain, targeting patients and physicians.

HealthtechMedical DevicesSan Jose, US

Mark Reiley(Director)inJeffrey W. Dunn(Executive Officer, Director)Robert E. Johnson(Executive Officer)Dan Murray(Executive Officer)Laura A. Francis(Chief Executive Officer)

BoardTimothy E. Davis(Director)

Board seatDavid Bonita· per SEC Form D · $21M raise · filed Jun 2016

Co-investorsArboretum VenturesMontreux Equity Partners

Spruce Biosciencessprucebiosciences.comin𝕏NASDAQ: SPRBFeb 2020SEC filingmedium confidence

Spruce Biosciences develops and commercializes therapies for serious neurological and endocrine disorders with unmet medical need, with a lead investigational enzyme replacement therapy (TA-ERT) for Mucopolysaccharidosis Type IIIB (Sanfilippo Syndrome Type B).

BiotechHealthtechSouth San Francisco, US

Samir Gharib(Executive Officer)inRICHARD KING(Executive Officer, Director)inJavier Szwarcberg(Chief Executive Officer)in

BoardSimpson Camilla(Director)Tiba Aynechi(Director)inBali Muralidhar(Director)in

Board seatDina Chaya· per SEC Form D · $53.6M raise · filed Feb 2023

Co-investorsAisling CapitalHealthCapRiverVest Venture PartnersAbingworthNorwest Venture PartnersNovo Holdings+1 more

Synlogicsynlogictx.comin𝕏OTC: SYBXMay 2017SEC filingmedium confidence

Synlogic develops synthetic biology-based biotherapeutics that use engineered living organisms to treat diseases.

BiotechDeep TechMedical DevicesCambridge, US

Bharatt Chowrira(Executive Officer)inMichael Sheahan(Executive Officer)Jose Carlos Gutierrez-Ramos(Executive Officer, Director)inPaul Miller(Executive Officer)inAoife Brennan(Executive Officer)inTodd Shegog(Executive Officer)in

Board seatChau Khuong· per SEC Form D · $42M raise · filed May 2017

Co-investorsAtlas VentureCLI VenturesNew Enterprise Associates (NEA)NSG VenturesPfizer Venture InvestmentsSofinnova Ventures+1 more

Adagio TherapeuticsNASDAQ: IVVDApr 2021 · $336M

Invivyd develops monoclonal antibody therapies to prevent and treat serious viral infections, beginning with COVID-19 and expanding to respiratory syncytial virus and measles.

BiotechWaltham, US

Tillman U. Gerngross(Executive Officer, Director)Lynn Connolly(Executive Officer)Eric Kimble(Executive Officer)inHalley Gilbert(Executive Officer)Rebecca Dabora(Executive Officer)inEllie Hershberger(Executive Officer)

Co-investorsGV (Google Ventures)Fidelity InvestmentsForesite CapitalMithril Capital ManagementOmega FundsPolaris Partners+3 more

Adaptive Biotechnologiesadaptivebiotech.comin𝕏NASDAQ: ADPT

Adaptive Biotechnologies applies the genetics of the adaptive immune system to diagnostics and therapeutics, translating immune-system data into clinical insights for clinicians and biopharma companies.

AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesSeattle, US

Chad Robins(Chief Executive Officer, Co-founder, Chairman of the Board)inHarlan Robins(Co-founder; Chief Scientific Officer until 2026)inKathleen Determann(Executive Officer)inDean Schorno(Executive Officer)inChris Carlson(Executive Officer)Kyle Piskel(Chief Financial Officer)in

Co-investorsDecheng CapitalFMG CapitalForesite CapitalKhosla VenturesViking GlobalCasdin Capital

Alumisalumis.comin𝕏NASDAQ: ALMS

Alumis is a clinical-stage biopharmaceutical company developing a late-stage portfolio of targeted therapies for immune-mediated diseases.

AI & Machine LearningBiotechDigital HealthHealthtechLongevitySouth San Francisco, US

Martin Babler(President, Chief Executive Officer and Chairman of the Board)inMark Bradley(Chief Development Officer)inKolbot By(SVP, Head of Technical Operations)inJack Danilkowicz(Chief Commercial Officer)inJörn Drappa(Chief Medical Officer)inDavid M Goldstein(Chief Scientific Officer)in

Co-investorsForesite CapitalHBM Healthcare InvestmentsHBM PartnersNextech InvestSamsara BioCapitalSR One Capital Management+3 more

Aura Biosciencesaurabiosciences.comin𝕏NASDAQ: AURA

Aura Biosciences develops Virus-Like Drug Conjugates (VDCs), a platform using Virus-Like Particles conjugated with drugs or loaded with nucleic acids to target solid tumors.

BiotechHealthtechMedical DevicesCambridge, US

Elisabet de los Pinos, Ph.D.(Executive Officer, Director)Elisabet de los Pinos(Founder)inMichael Wyzga(Executive Officer)Dale Pfost, Ph.D.(Director)Alan E. Walts, Ph.D.(Director)Lewis Geffen(Executive Officer)

Co-investorsAdvent Life SciencesChiesi VenturesColumbus Venture PartnersDroia VenturesForesite CapitalJazzya Investments+6 more

Avita Medicalavitamedical.comin𝕏NASDAQ: RCELNov 2019

RECELL is an FDA-approved autologous skin cell suspension device for treating burns, trauma, and surgical wounds by harvesting a patient's own skin cells and applying them to accelerate healing and reduce the need for large skin grafts.

BiotechHealthtechMedical DevicesMelbourne, US

Fiona WoodDale A Sander(Executive Officer)inCary Vance(Executive Chairman & Interim Chief Executive Officer)in

BioAge Labsbioagelabs.comin𝕏NASDAQ: BIOAFeb 2024

BIOAGE develops therapies targeting the molecular pathways that drive aging to increase healthspan and address age-related chronic diseases.

BiotechHealthtechLongevityRichmond, US

Kristen Fortney, PhD(Co-Founder, CEO)Eric Morgen, MD(Co-Founder, COO)Kristen Fortney(Founder)inEric Morgen(Founder)inDov Goldstein(Executive Officer)in

BoardPatrick Enright(Director)in

Co-investorsAndreessen HorowitzElad GilFelicis VenturesGreen Sands EquityIA Seed VenturesLongitude Capital+19 more

Biomxbiomx.comin𝕏NYSE: PHGE

BiomX builds a portfolio of defense and security companies through subsidiaries, partnerships, and acquisitions, focusing on detection systems, aerial technologies, and infrastructure security.

AI & Machine LearningBiotechCybersecurityDeep TechDefense TechHardwareNess Ziona

Jonathan Solomon(Chief Executive Officer)inMerav Bassan(Chief Development Officer)inMarina Wolfson(Chief Financial Officer)inJesse Goodman(Director)Alan Moses(Director)Jonathan Leff(Director)

Co-investorsAMR Action FundBaruch Future VenturesNSG VenturesSBI JI Innovation Advisory Ltd.Seventure Partners8VC+2 more

Caris Life Sciencescarislifesciences.comin𝕏NASDAQ: CAIOct 2020 · $240M

Caris Lifesciences operates a precision oncology platform that analyzes DNA, RNA and proteins across tissue and blood to profile a patient's cancer and match treatments and clinical trials.

AI & Machine LearningBiotechHealthtech

David Dean Halbert(Chairman, Founder and CEO)

Co-investorsCoatue ManagementSilver Lake PartnersSixth StreetBraidwellMillennium Management

Crinetics Pharmaceuticalscrinetics.comin𝕏NASDAQ: CRNX

Crinetics is a pharmaceutical company focused on discovering, developing, and commercializing therapies for endocrine diseases and endocrine-related conditions.

BiotechSan Diego, US

Richard Scott Struthers(Executive Officer, Director)Stephen Betz(Chief Scientific Officer)inR. Scott Struthers(President, Chief Executive Officer and Director)inTobin Schilke(Chief Financial Officer)inIsabel Kalofonos(Chief Commercial Officer)inYunFei Zhu(Executive Officer)

Co-investors5AM VenturesForesite CapitalRA CapitalVivo Capital

Cullinan Therapeuticscullinantherapeutics.com𝕏NASDAQ: CGEM

Cullinan Therapeutics is a clinical-stage biotech company developing therapeutic molecules for autoimmune diseases and cancer, with expertise in immune modulation.

BiotechHealthtechMedical Devices

Mary Kay Fenton(Chief Financial Officer)inJeffrey Jones(Chief Medical Officer)Jennifer Michaelson(Chief Scientific Officer)inCorinne Savill(Chief Business Officer)inJacquelyn Sumer(Chief Legal and Compliance Officer and Secretary)inNadim Ahmed(President and Chief Executive Officer)in

Co-investorsForesite CapitalNextech InvestBiotechnology Value Fund

CytomX Therapeuticscytomx.comin𝕏NASDAQ: CTMX

CytomX is a clinical-stage biopharmaceutical company developing conditionally activated biologic cancer therapies, including antibody-based treatments designed to target tumors while limiting effects on healthy tissue.

BiotechHealthtechSouth San Francisco, US

Sean A. McCarthy(Chief Executive Officer and Chairman)inMarcia P. Belvin(SVP, Chief Scientific Officer)inDawn Benson(SVP, Quality and Product Manufacturing)inWayne Chu(Chief Medical Officer)Rachael Lester(SVP, Chief Business Officer)inChris Ogden(Chief Financial Officer)in

Co-investorsATEL VenturesCanaan PartnersLongitude CapitalPfizer Venture InvestmentsWellington ManagementThird Rock Ventures

Damora TherapeuticsNASDAQ: DMRA

Damora Therapeutics is a preclinical-stage biotechnology company that discovers and develops therapeutic candidates, including DMR-001, DMR-002, and DMR-003, with the goal of advancing treatments through investigational drug applications and clinical trials.

BiotechCopenhagen, US

Garrett Winslow(Executive Officer)inLori Firmani(Executive Officer)inHans T. Schambye(Executive Officer, Director)Jennifer Jarrett(President, Chief Executive Officer and Director)inBecker Hewes(Chief Medical Officer)Sherwin Sattarzadeh(Chief Operating Officer)

Co-investorsAccess BiotechnologyViking GlobalAndreessen HorowitzBAM ElevateBay City CapitalCommodore Capital+8 more

DarioHealthdariohealth.comin𝕏NASDAQ: DRIOJun 2022 · $50M

Dario provides digital tools and support to help people manage chronic conditions such as diabetes between provider visits.

BiotechDigital HealthHealthtechMental HealthWellness & FitnessNew York, US

Oren Fuerst, PhD(Director)Erez Raphael(Chief Executive Officer)inZvi Ben David(Chief Financial Officer, Treasurer, and Secretary)inSteven Nelson(Chief Commercial Officer)inGadi Levin(Executive Officer, Director)in

BoardAdam K. Stern(Director)

Co-investorsAgate Medical Investments LPLeo Capital VenturesPitango

Disc Medicinediscmedicine.comin𝕏NASDAQ: IRONSep 2021 · $90M

Disc Medicine is a biopharmaceutical company developing therapies from discovery through clinical development for patients in need.

BiotechHealthtech

John Quisel(Chief Executive Officer)inJean Franchi(Chief Financial Officer)inJonathan Yu(Chief Operating Officer)inWill Savage(Chief Medical Officer)inPamela Stephenson(Chief Commercial Officer)inSteve Caffé(Chief Regulatory Officer)in

Co-investorsAccess BiotechnologyAtlas VentureBain Capital Life SciencesForesite CapitalFrazier Life Sciences5AM Ventures+7 more

Edgewise Therapeuticsedgewisetx.comin𝕏NASDAQ: EWTX

Edgewise Therapeutics discovers and develops small molecule medicines targeting muscle proteins to treat neuromuscular and cardiac diseases, including sevasemten for muscular dystrophies and EDG-7500 for cardiomyopathy, leveraging a proprietary drug discovery platform based on muscle physiology and high-throughput functional assays.

BiotechDigital HealthBoulder, US

Kevin Koch(Executive Officer, Director)inAlan Russell(Director)inBadreddin Edris(Director and Co-Founder)inKenneth Harrison(Director)

BoardPeter Thompson(Director)inJonathan Root(Director)in

Co-investorsBoulder VenturesForesite CapitalUS Venture PartnersViking GlobalWellington ManagementDeerfield Management Company+1 more

Emergent Biosolutionsemergentbiosolutions.comin𝕏NYSE: EBSOct 2018

Emergent BioSolutions is a public health company that develops, manufactures, and supplies medical countermeasures for national security and preparedness, along with commercialized products addressing threats such as the opioid epidemic.

Advanced ManufacturingBiotechHealthtechGaithersburg, US

Fuad El-Hibri(Director, Executive Officer)inRobert G Kramer(Executive Officer)inKatherine Strei(Executive Officer)Adam R Havey(Executive Officer)inDaniel J Abdun-Nabi(Executive Officer, Director)inJoseph C. Papa(President, CEO and Director)

Co-investorsAdvent Life Sciences

Enliven Therapeuticsenliventherapeutics.cominNASDAQ: ELVN

Enliven Therapeutics is a clinical-stage biopharmaceutical company that discovers and develops small molecule therapeutics using a precision medicine approach, with a focus on oncology and hematology.

BiotechHealthtechBoulder, US

Sam Kintz(Co-founder and Head of Pipeline)inJoe Lyssikatos(Co-founder and Research Fellow)Anish Patel(Co-founder and Chief Operating Officer)Rick Fair(Chief Executive Officer and Member of the Board of Directors)inHelen Collins(Chief Medical Officer)inBen Hohl(Chief Financial Officer and Head of Corporate Development)in

Co-investors5AM VenturesPfizer Venture InvestmentsRoche Venture FundARCH Venture PartnersBay City CapitalJanus Henderson Investors+2 more

Forte BiosciencesNASDAQ: FBRX

Forte Biosciences is a clinical-stage biopharmaceutical company developing FB102, an anti-CD122 monoclonal antibody intended to treat autoimmune diseases including celiac disease, vitiligo, alopecia areata, and type 1 diabetes by modulating immune cell activity.

BiotechSherman Oaks, US

Paul A. Wagner(Chairman, President, Chief Executive Officer and Director)inAntony A. Riley(Chief Financial Officer)inTuan Huynh(Director)Lawrence Eichenfield(Director)

Insmedinsmed.comin𝕏NASDAQ: INSM

Insmed is a biopharmaceutical company that provides grants and charitable funding to support healthcare provider education and patient care initiatives focused on nontuberculous mycobacterial lung disease, non-cystic fibrosis bronchiectasis, and other serious lung diseases.

BiotechDigital HealthHealthtechMedical Devices

Will Lewis(Chair and Chief Executive Officer)inGeoffrey AllaninSara Bonstein(Chief Financial Officer)inRoger Adsett(Chief Operating Officer)Martina Flammer(Chief Medical Officer)inS. Nicole Schaeffer(Chief People Strategy Officer)in

Co-investorsBessemer Venture PartnersF-Prime CapitalForesite CapitalHercules Capital, Inc.Prospect Venture PartnersRidgeback Capital+1 more

InspireMDinspiremd.comNASDAQ: NSPRJul 2025 · $58M

InspireMD develops and commercializes medical devices for vascular intervention, including carotid stent systems and embolic protection systems sold through direct sales in the United States and via distributors in international markets.

BiotechHealthtechMiami, US

Patrick Verta(Executive Officer)inPete Ligotti(Executive Officer)inMike Lawless(Chief Financial Officer)Shane Gleason(Executive Officer)inMarvin Slosman(President and Chief Executive Officer)inAndrea Tommasoli(Chief Operating Officer)

Intellia Therapeuticsintelliatx.comin𝕏NASDAQ: NTLAAug 2015

Intellia Therapeutics develops in vivo and ex vivo CRISPR/Cas9 gene editing therapies aimed at treating the root causes of severe genetic diseases, with lead candidates for hereditary angioedema and ATTR amyloidosis.

BiotechDeep TechHealthtechCambridge, US

Nessan Bermingham(Founder)inJennifer Doudna(Founder)Jose Rivera(Executive Officer)inJohn Leonard(President and Chief Executive Officer)inJames Basta(Executive Vice President, General Counsel and Corporate Secretary)inEdward Dulac(Executive Vice President, Chief Financial Officer)in

Co-investorsage1Atlas VentureAvoro Capital AdvisorsEcoR1 CapitalForesite CapitalRidgeback Capital+1 more

Invivydinvivyd.comin𝕏NASDAQ: IVVD

Invivyd develops monoclonal antibody medicines for the prevention and treatment of serious viral infectious diseases, starting with COVID-19 and other high-need indications.

BiotechHealthtech

Marc Elia(Founder)in

Co-investorsBain Capital Life SciencesForesite CapitalMRL Ventures FundPremji InvestRA CapitalGV (Google Ventures)+2 more

NeuroPaceneuropace.comin𝕏NASDAQ: NPCEAug 2020

NeuroPace is a commercial-stage medical device company that develops the RNS System, a brain-responsive neurostimulation platform delivering real-time treatment at the seizure source for patients with drug-resistant epilepsy and other brain disorders.

Digital HealthHardwareHealthtechMedical DevicesMountain View, US

Rebecca Kuhn(Executive Officer)inFrank Fischer(Executive Officer, Director)Joel Becker(President, Chief Executive Officer and Director)inVince Burgess(Director)inRenee Ryan(Director)inRay Larkin(Director)

Co-investorsAccelmed PartnersNew Enterprise Associates (NEA)

Oncology InstituteNASDAQ: TOI

The Oncology Institute operates a national network of 65 affiliated physician clinics and contracts with independently-owned oncology and hematology practices to deliver outpatient cancer care through fee-for-service arrangements and value-based contracts that shift financial risk to the company.

HealthtechCerritos, US

Robert Carter(Executive Officer)Jeremy Castle(Executive Officer)Daniel Virnich(Executive Officer, Director)Yale Podnos(Executive Officer)inBrad Hively(Director)Mihir Shah(Executive Officer)in

Onconova TherapeuticsinNASDAQ: TRAW

Traws Pharma (formerly Onconova Therapeutics) develops investigational antiviral agents targeting respiratory viral infections and certain cancers, with four clinical-stage programs including a cap-dependent endonuclease inhibitor for influenza and bird flu, a protease inhibitor for COVID-19, and two kinase inhibitors for solid tumors and blood cancers.

BiotechNewtown, US

Ramesh Kumar, Ph.D(Executive Officer, Director)E. Premkumar Reddy(Director)Manoj Maniar(Executive Officer)inThomas McKearn(Executive Officer)Ajay Bansal(Executive Officer)inSteven Fruchtman(Executive Officer)in

ORIC Pharmaceuticalsoricpharma.cominNASDAQ: ORIC

ORIC Pharmaceuticals is a clinical-stage oncology company developing therapies aimed at overcoming cancer treatment resistance, including innate, acquired, and bypass resistance.

BiotechHealthtechSouth San Francisco, US

Richard Heyman(Chairman, Founder, Scientific Advisory Board)inCharles Sawyers(Founder, Scientific Advisory Board)Scott Lowe(Founder, Scientific Advisory Board)Dominic Piscitelli(Chief Financial Officer)inPratik Multani(Chief Medical Officer)inJacob Chacko(President, Chief Executive Officer and Board Member)in

Co-investorsEcoR1 CapitalNew Enterprise Associates (NEA)Nextech InvestTaiho Ventures, LLCThe Column GroupViking Global

Passage Biopassagebio.comin𝕏NASDAQ: PASGAug 2019 · $110M

Passage Bio is a biotechnology company developing treatments for central nervous system (CNS) diseases, with a focus on neurodegenerative conditions.

BiotechHealthtechPhiladelphia, US

William Chou(Chief Executive Officer)Tadataka Yamada(Executive Officer, Director, Promoter)Stephen Squinto(Executive Officer, Director)in

BoardPatrick Heron(Director)inCarl Gordon(Director)inThomas Street Address 1 Woiwode(Director)

Co-investorsFrazier Life SciencesAccess BiotechnologyFrazier Healthcare PartnersLilly Asia VenturesNew Leaf Venture PartnersSphera Funds Management+2 more

Relmada Therapeuticsrelmada.comNASDAQ: RLMDMar 2026 · $160M

Relmada is a clinical-stage biopharmaceutical company developing therapies including NDV-01, a sustained-release intravesical formulation of gemcitabine and docetaxel for non-muscle invasive bladder cancer, and Sepranolone, a candidate targeting compulsive behaviors via GABAA receptor modulation.

BiotechHealthtechNew York, US

Sergio Traversa(Executive Officer, Director)Paul Kelly(Director)Maged Shenouda(Director)inEliseo O. Salinas(President and Chief Scientific Officer)inDouglas Beck(Chief Financial Officer)Charles Ence(Chief Accounting and Compliance Officer)

Co-investorsBioAdvanceBAM ElevateBraidwellCommodore CapitalJanus Henderson InvestorsRA Capital+2 more

Shattuck Labsshattucklabs.cominNASDAQ: STTK

Shattuck Labs is a biotechnology company developing biologic medicines targeting TNF receptors, including the TL1A/DR3 axis, for patients with cancer and inflammatory or life-altering diseases.

BiotechHealthtechAustin, US

Josiah Hornblower(President/CEO)inTaylor(Co-founder & Chief Executive Officer, Board Member)

BoardWalter Loewenbaum(Director)

Co-investorsEcoR1 CapitalHatteras Venture PartnersRocky Point VenturesREDMILET. Rowe Price

Sonendosonendo.comOTC: SONXJun 2013

Sonendo is a medical technology company that develops and manufactures the GentleWave System, a technology platform for treating tooth decay by cleaning and disinfecting the interior spaces of teeth without removing tooth structure.

HardwareHealthtechMedical DevicesLaguna Hills, US

Bjarne Bergheim(Executive Officer, Director)inJohn McGaugh(Executive Officer)inJohn Bostjancic(Executive Officer)Hugh Neuharth(Executive Officer)Roy T. Chen(Chief Talent Officer)Chris Guo(Interim Chief Financial Officer)in

Co-investorsEssex Woodlands Healthcare PartnersFjord VenturesGeneral AtlanticMeritech Capital PartnersNeomed ManagementPura Vida Investments+1 more

TELA Biotelabio.comin𝕏NASDAQ: TELA

Offers soft tissue repair solutions combining naturally sourced tissue with polymer; lead product OviTex for hernia repair (NASDAQ: TELA), based in Malvern, PA.

BiotechMalvern, US

Antony Koblish(Founder)inFrancis Conway(Executive Officer)Maarten Persenaire(Executive Officer)Christine Arasin(Executive Officer)

BoardKevin Rakin(Director)inAshley Freidman(Director)

Co-investorsCheckmate Capital Group LLCEssex Woodlands Healthcare PartnersHighCape CapitalSignet Healthcare Partners1315 CapitalRTW Investments L.P.

Trawspharmatrawspharma.comNASDAQ: TRAW

Traws Pharma is a pharmaceutical company developing therapeutics, with a leadership focus spanning oncology, infectious disease, and medical science areas.

BiotechHealthtech

Iain Dukes(Chief Executive Officer)inCharles Parker(Chief Financial Officer)C. David Pauza, PhD(Chief Science Officer)Robert R. Redfield, MD(Chief Medical Officer)Victor Moyo, MD(CMO Oncology)Nikolay Savchuk, PhD(Chief Operating Officer)

Verastemverastem.comin𝕏NASDAQ: VSTM

Verastem Oncology is a biopharmaceutical company that discovers and develops drugs to treat cancer patients.

BiotechMedical DevicesNeedham, US

Robert WeinbergRICHARD ALDRICH(Director)AMY C. CAVERS(Executive Officer)inCATHY CAREW(Executive Officer)inJONATHAN PACHTER(Executive Officer)inROB GAGNON(Executive Officer)in

Co-investorsBessemer Venture PartnersCardinal PartnersForesite CapitalLightstone VenturesLongwood FundOberland Capital+1 more

Verricaverrica.comin𝕏NASDAQ: VRCA

Verrica Pharmaceuticals is a therapeutics company developing and commercializing treatments for dermatological diseases, including molluscum contagiosum, common warts, and skin cancers such as basal cell and squamous cell carcinoma.

BiotechHealthtechMedical DevicesWest Chester, US

Noah Rosenberg(Executive Officer)inJohn Kirby(Executive Officer)Matthew Davidson(Executive Officer, Director)

BoardJayson Rieger(Executive Officer, Director)inPaul B. Manning(Director)inDavid Zawitz(Executive Officer)

Co-investorsPBM Capital

Alpheus Medicalalpheusmedical.cominMay 2025✓ verified

Alpheus is a clinical-stage biotechnology company developing Porphyrin Metabolite Activation (PoMA™), a drug-led oncology approach designed to treat glioblastoma using proprietary low-intensity ultrasound to activate tumor-localized porphyrin metabolites.

BiotechHealthtechMedical DevicesChanhassen, US

Jeremy Ling(Executive Officer)inSteve Weiner(Executive Officer)Vijay Agarwal(Founder, President and CEO)inWilliam Davis(Executive Officer, Director)

BoardImran Eba(Executive Officer)in

Board seatKlaus Veitinger· per SEC Form D

Co-investorsHealthQuest CapitalSamsara BioCapitalSV Health InvestorsAction Potential Venture Capital Ltd.BrightEdge

Perfuse Therapeuticsperfusetherapeutics.cominMar 2019✓ verified

Perfuse Therapeutics develops novel ocular therapies for retinal and glaucoma diseases through drug delivery and formulation platforms.

BiotechHealthtechMedical DevicesSan Francisco, US

Sevgi Gurkan(Founder, Chief Executive Officer, and Member of the Board of Directors)in

BoardChristy Shaffer(Director)

Board seatChau Khuong· per SEC Form D

Co-investorsAccess BiotechnologyCatalio Capital Management, LPHatteras Venture PartnersLAVLilly Asia VenturesHatteras

ADARx Pharmaceuticalsadarx.cominSeries B · Sep 2021 · $75M✓ verified

ADARx is a clinical-stage biotechnology company developing RNA-targeted therapeutics designed to control the expression of disease-driving genes.

BiotechHealthtechMedical DevicesSan Diego, US

Zhen Li(Co-founder, President & CEO)inRui Zhu(Founding Member & Chief Technology Officer)Rob Ackles(Chief People Officer)inRyan Fisk(Chief Financial Officer & Chief Business Officer)inRobert A. MacLeod(Chief Scientific Officer)inChristopher Claeboe(Senior Vice President of Operations)in

Co-investorsBain Capital Life SciencesSR One Capital ManagementLilly Asia VenturesT. Rowe PriceAscenta CapitalTCG Crossover+3 more

Aer Therapeuticsaertherapeutics.comin✓ verified

Aer Therapeutics develops a science-driven therapeutic aimed at eliminating mucus plugs in the lungs to treat muco-obstructive lung diseases such as COPD and asthma.

BiotechHealthtechMedical DevicesRaleigh, US

Thomas Mathers(Executive Officer, Director)inJames Shaffer(Executive Officer, Director)John Fahy(Director)in

BoardChristy Shaffer(Director)inRishi Gupta(Director)inTim Shannon(Director)in

Co-investorsHatteras Venture PartnersCanaan PartnersPappas Capital

Alentis Therapeuticsalentis.chin✓ verified

Alentis is a biotech company developing therapies for chronic liver disease, fibrosis, and cancer based on the molecular biology of liver disease.

AI & Machine LearningBiotechHealthtechMedical DevicesBasel, CH

Thomas Baumert(Founder)inMark Pruzanski(Chief Executive Officer)inLuigi Manenti(Chief Medical Officer)inJon Freve(Chief Financial Officer)inBryan Yoon(General Counsel and Chief Administrative Officer)inAditya Venugopal(Chief Business Officer)in

Co-investorsAvego BioScience CapitalBioMedPartnersFrazier Life SciencesJeito CapitalLongitude CapitalNovo Holdings+5 more

Aspen Neuroscienceaspenneuroscience.comin𝕏Seed · Apr 2020 · $70M✓ verified

Aspen Neuroscience develops iPSC-derived autologous cell therapies for neurological diseases, with a lead product (ANPD001) in Phase 1/2a clinical trials for Parkinson's disease.

BiotechDeep TechDigital HealthMedical DevicesSan Diego, US

Andrés Bratt-Leal(Co-Founder and Senior Vice President, Research & Development)inANDRÉS BRATT-LEAL, Ph.D.(Co-Founder; Senior Vice President, Research & Development)Damien McDevitt(President and Chief Executive Officer)inDAMIEN MCDEVITT, Ph.D.(President and Chief Executive Officer)

Co-investorsARCH Venture PartnersLifeforce CapitalDomain AssociatesEDB InvestmentsSection 32Frazier Life Sciences+9 more

Brenigbrenigther.comin𝕏✓ verified

Brenig Therapeutics is a biotechnology company developing small-molecule therapies for Parkinson's disease and other neurodegenerative disorders, using AI-driven drug discovery.

AI & Machine LearningBiotechHealthtechDover, US

Megan McGill(Chief Executive Officer)inIain Dukes(Chief Business Officer / Chairman of the Board)inNikolay Savchuk(Chief Operating Officer)Tien Dam(Chief Medical Officer)in

Co-investorsNew Enterprise Associates (NEA)BGVTorrey Pines Investment

Congruence Therapeuticscongruencetx.cominSeries A · Feb 2022 · $50M✓ verified

Congruence is a drug discovery company that applies protein dynamics, biophysics, machine learning, and computational chemistry to model proteins in their full dynamic state and predict disease correction in silico.

AI & Machine LearningBiotechDeep Tech

Clarissa Desjardins(Founder)in

Co-investorsAlexandriaDIMENSIONAngelini VenturesBDC Thrive Venture Fund for WomenLumira VenturesAmplitude Venture Capital+1 more

Corteria Pharmaceuticalscorteriapharma.comin✓ verified

Corteria Pharma develops interceptive therapies aimed at treating subpopulations of patients with heart failure, sarcopenia, and obesity.

BiotechDigital HealthHealthtechLongevity

Philip JaniakinMarie-Laure OzouxinRégis OlivierinFrancesca C. LawsonMark KowalaEleonore Jouannyin

Co-investorsFountain Healthcare PartnersJeito CapitalKurma PartnersV-Bio VenturesOmnes CapitalInvivo Capital Partners+1 more

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

BELLUS HealthClementia PharmaceuticalsCurevo, Inc.FORE US BioIgenica BiotherapeuticsIkena Oncology, Inc.Prevail TherapeuticsRestora MedicalSpringWorks TherapeuticsSymbiomix TherapeuticsADARxAduro BiotechAige010Aragon PharmaceuticalsAttenuaAvalo TherapeuticsAzura OpthalmicsBailiBiokinBionovapharmaBlossomHill TherapeuticsCreditpharmaDlabsciEddingpharmEthrisEurolifehealthcareForSight VISION6 IncFortebiorxFuturx

Browse all 338 investments with full details →

▶138 more tracked companies

GaushGelesisGenewizGennaoGenocuryGood Doctor Cloud HealthHarpoon TherapeuticsHarvestiroHelicore BiopharmaHysyylIambicIkenaoncologyImmune PathInnovate BiopharmaceuticalsInnvolutionInnvolution Healthcare Private LimitedIntelliaInventisbioIswarya FertilityJanux TherapeuticsJinxin Fuxing EldercareJxfxkyKapivaKartostheraKoya MedicalKumquat BiosciencesLaekna TherapeuticsLattice MedTech Private LimitedLaxmi DentalLaxmidentallealLeal TherapeuticsLexeotxLifecellLogicbioLomondtherLoxoLoxo OncologyLupeng PharmaceuticalLycia TherapeuticsMagenta MedicalMarksans PharmaMBX BiosciencesMDxHealthMedpharmMemeBoxMendraMID LabsMinghuipharmaMinvervaXMiradorMirador TherapeuticsMobileodtMondegobioMyriad GeneticsNanotronicsNerre TherapeuticsNeurelisNewmedNorchem PharmaNucleixNucleusradOdyssey TherapeuticsPath AiPathalysPee SafePic TherapeuticsPinnacle MedicinesPionyr ImmunotherapeuticsPMV PharmaPostmatesPractice FusionPrincipia BiopharmaProlynxProlynxincPropellerProVerumProviva TherapeuticsPulnovo MedicalRadiuspharmRampart BioscienceRAPT TherapeuticsRayTheraReCode TherapeuticsReliabiotechRenasant BioRepare TherapeuticsReparerxReViralSeroba Life SciencesSidewinder TherapeuticsSikkaSikkasoftSilverback TherapeuticsSingulexSitalaSiteOne TherapeuticsSneuroSpectronrxStairmedStar TherapeuticsStarling OncologyStratus TherapeuticsSuraksha DiagnosticSynthorxTandemaiTendfoTerremotobioThe Oncology InstituteTheseusThird Harmonic BioTigerConnectTopaz TxTP TherapeuticsTriSalus Life SciencesTrisaluslifesciTriveniTrunativTurnstone BiologicsTytoTyto CareUnilifeUpper BiotechUrotronicVelosbioVelseraVerdiva BioVerrica PharmaceuticalsVivacta BioVvardisWindward BioYarrowYarrowbioscienceZaiZentera TherapeuticsZenteratxZion PharmaZyloxtb

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

Exits · 63

51 IPOs · 12 acquisitions · showing 56

Q32 BioNASDAQ: QTTBScribe TherapeuticsNASDAQ: SCTXSionna TherapeuticsNASDAQ: SIONUpstream BioNASDAQ: UPBAadi BioscienceNASDAQ: WHWKAdicet BioNASDAQ: ACETArvinas Holding Co. LLCNASDAQ: ARVNCalcimedicaNASDAQ: CALCCompass TherapeuticsNASDAQ: CMPXImaraNASDAQ: ELVNKeros TherapeuticsNASDAQ: KROSMirna TherapeuticsOTC: SYBXNextCureNASDAQ: NXTCPrelude TherapeuticsNASDAQ: PRLDSI-BONENASDAQ: SIBNSpruce BiosciencesNASDAQ: SPRBSynlogicOTC: SYBXAdagio TherapeuticsNASDAQ: IVVDAdaptive BiotechnologiesNASDAQ: ADPTAlumisNASDAQ: ALMSAura BiosciencesNASDAQ: AURAAvita MedicalNASDAQ: RCELBioAge LabsNASDAQ: BIOABiomxNYSE: PHGECaris Life SciencesNASDAQ: CAICrinetics PharmaceuticalsNASDAQ: CRNXCullinan TherapeuticsNASDAQ: CGEMCytomX TherapeuticsNASDAQ: CTMXDamora TherapeuticsNASDAQ: DMRADarioHealthNASDAQ: DRIODisc MedicineNASDAQ: IRONEdgewise TherapeuticsNASDAQ: EWTXEmergent BiosolutionsNYSE: EBSEnliven TherapeuticsNASDAQ: ELVNForte BiosciencesNASDAQ: FBRXInsmedNASDAQ: INSMInspireMDNASDAQ: NSPRIntellia TherapeuticsNASDAQ: NTLAInvivydNASDAQ: IVVDNeuroPaceNASDAQ: NPCEOncology InstituteNASDAQ: TOIOnconova TherapeuticsNASDAQ: TRAWORIC PharmaceuticalsNASDAQ: ORICPassage BioNASDAQ: PASGRelmada TherapeuticsNASDAQ: RLMDShattuck LabsNASDAQ: STTKSonendoOTC: SONXTELA BioNASDAQ: TELATrawspharmaNASDAQ: TRAWVerastemNASDAQ: VSTMVerricaNASDAQ: VRCAAduro Biotechacq. by Chinook TherapeuticsAvedro, Inc.acq. by GlaukosAvitideacq. by RepligenDimension Therapeuticsacq. by Ultragenyx PharmaceuticalForteBioacq. by Pall

Portfolio news

latest coverage across their companies

Fund performance · per public LP disclosures · 10

as of Sep 2025
FundVintageCommittedNet IRRTVPIDPI
OrbiMed Private Investments IX, LPLPs: California State Teachers' Retirement System, New Mexico Educational Retirement Board, Kern County Employees' Retirement Association2022—29.3%1.16x0.21x
OrbiMed Royalty & Credit Opportunities IVLPs: California State Teachers' Retirement System, Sacramento County Employees' Retirement System, Kern County Employees' Retirement Association2022—14.1%1.28x0.25x
OrbiMed Private Investments VIII, L.P.LPs: California State Teachers' Retirement System, New Mexico Educational Retirement Board2020—6.9%1.19x0.30x
OrbiMed Royalty & Credit Opportunities III, LPLPs: California State Teachers' Retirement System, Sacramento County Employees' Retirement System2019—15.1%1.20x0.95x
OrbiMed Private Investments VILPs: Oregon Public Employees Retirement System2015—13.0%1.64x1.18x
OrbiMed Private Investments VLPs: Oregon Public Employees Retirement System, California State Teachers' Retirement System2013—38.2%2.35x2.14x
OrbiMed Private Investments IVLPs: Oregon Public Employees Retirement System, California State Teachers' Retirement System, The Regents of the University of California +1 more2009—31.8%2.73x2.72x
Orbimed Private lnvesuncnts IV, L PLPs: The Regents of the University of California2009—36.2%2.67x0.45x
Orbimed Private Investments III, LPLPs: The Regents of the University of California2006—18.1%2.34x1.48x
Orbimed Private lnvesunents Ill, LPLPs: The Regents of the University of California2006—18.4%2.32x—

Source: public limited-partner disclosures (CalPERS, CalSTRS). Net IRR / TVPI / DPI as reported by the limited partner; a fund's early-year IRR is an interim estimate (J-curve).

IPO stake values · per SEC filings · 17

Value of this firm's stake in each portfolio company at its IPO price, from the prospectus principal-stockholder table.

CompanyOwnedIPO priceAt IPOStake value
Prelude Therapeutics28.8%$60.00Jan 2021$935.7M
Passage Bio14.2%$18.00Feb 2020$112.7M
NextCure10.1%$36.75Nov 2019$99.6M
Adagio Therapeutics4.6%$17.00Aug 2021$84.7M
Invivyd4.6%$17.00Aug 2021$84.7M
Upstream Bio9.5%$17.00Oct 2024$82.8M
ORIC Pharmaceuticals8.2%$23.00Nov 2020$67.2M
Adicet Bio15.8%$15.00Jan 2018$64.5M
NeuroPace16.4%$17.00Apr 2021$64.2M
Calcimedica17.9%$16.00Sep 2020$57.6M
Sionna Therapeutics7.4%$18.00Feb 2025$56.8M
Damora Therapeutics13.7%$15.00Oct 2020$50.4M
Intellia Therapeutics6.9%$18.00May 2016$43.4M
Enliven Therapeutics9.6%$16.00Mar 2020$25.5M
Imara9.6%$16.00Mar 2020$25.5M
Verrica5.1%$15.00Jun 2018$19.2M
Scribe Therapeutics2.0%$15.00Jul 2026$5.2M

Source: SEC S-1 / 424B prospectus filings. Stake value = shares beneficially owned × the initial public offering price, as disclosed — a market value at IPO, not a return multiple (the firm's original cost is not disclosed).

Frequently asked questions

How many investments has OrbiMed made?
OrbiMed has 338 tracked investments, 63 of which have exited, including 38 dated in the last 24 months.
What stage does OrbiMed invest at?
OrbiMed invests at the Seed, Series A, Series B, Series C, Growth, Late Stage stages.
What is OrbiMed's typical check size?
OrbiMed typically writes checks of $1M – $75M.
What sectors does OrbiMed focus on?
OrbiMed focuses on AI & Machine Learning, Biotech, Digital Health, Healthtech, Longevity, Medical Devices.
Where is OrbiMed located?
OrbiMed is headquartered in New York, US.
Does OrbiMed lead rounds?
Yes, OrbiMed leads investment rounds.
Who does OrbiMed co-invest with?
OrbiMed most often shares deals with Foresite Capital, RA Capital, Frazier Life Sciences, among 274 tracked co-investors.

Media · Podcasts & interviews

featuring the team

Geoffrey C. Hsu, CFA, General Partner, OrbiMed Advisors LLC

Biotechnology Innovation Organization · Geoffrey C. Hsu

Co-investors · 87

Lilly Asia Ventures

Lilly Asia Ventures (LAV) is a biomedical venture capital firm with offices in Hong Kong, Shanghai, and Palo Alto, backing entrepreneurs building companies focused on breakthrough products that treat disease and improve human health.

Sofinnova Ventures

Sofinnova is an investment firm focused on the life sciences and biotechnology sector, partnering with companies from inception through drug development, regulatory approval, company building, and IPO.

$100K – $15M
$3M – $10M
SR One Capital Management

SR One Capital Management is a life sciences venture capital firm that takes a 'back-and-build' approach, providing entrepreneurs with human, intellectual, and financial resources. It emerged from the legacy SR One team formerly part of GSK.

5AM Ventures

5AM Ventures is a life science venture capital firm founded in 2002 that funds and builds next-generation life sciences companies, focusing on biopharmaceuticals, drug delivery technologies, and life science instruments.

$100K – $4M
Atlas Venture

Atlas Venture is a life sciences venture capital firm with three decades of experience investing in and building biotech and medical innovation companies, including startups launched from its own incubator.

$500K – $1M
OUP (Osage University Partners)

OUP (Osage University Partners) is a venture firm that invests in science-driven startups commercializing deep technology innovations emerging from university and breakthrough research.

$1M – $20M
Pfizer Venture Investments

Pfizer Venture Investments is a strategic venture fund that doesn't require product or technology rights as a condition of investing, giving founders independence while still aiming for future collaboration with Pfizer, and its team blends venture investing with business development and drug discovery expertise to back frontier scientific bets—such as neuroscience, in-vivo cell engineering, dark-genome target discovery, and the blockchain-based longevity accelerator VitaDAO—that many biotech investors avoid. The fund also runs an active China strategy through a locally based venture vehicle and direct investments like OTR Therapeutics, and it has become a channel for strategic deals, with portfolio companies acquired by AbbVie, Ipsen, and Gilead/Kite.

$5M – $20M
▶75 more co-investors

Aisling CapitalVivo CapitalNextech InvestSanofi VenturesAvoro Capital AdvisorsHBM PartnersvenBio PartnersAndreessen HorowitzGV (Google Ventures)Versant VenturesOmega FundsCanaan PartnersUS Venture PartnersForbionDeerfield Management CompanyNew Leaf Venture PartnersRTW Investments L.P.Khosla VenturesKleiner PerkinsThird Rock VenturesAbingworthPivotal Life SciencesSV Health InvestorsAndera PartnersAdvent Life SciencesFounders FundLightspeed Venture PartnersThe Column GroupFrazier Healthcare PartnersVida VenturesWestlake Village BioPartnersJMI EquityBorealis VenturesSequoia CapitalGeneral CatalystMenlo VenturesTiger Global ManagementTrinity VenturesVenrockPolaris PartnersPear VCPitangoSofinnova PartnersMPM BioImpactHatteras Venture PartnersYsios Capital6 Dimensions CapitalLongwood FundBessemer Venture PartnersCRV (Charles River Ventures)General AtlanticEQT Life SciencesDimension CapitalRiverVest Venture PartnersDCVC (Data Collective)Meritech Capital PartnersDomain AssociatesFlagship Pioneering1955 CapitalDFJSeroba Life SciencesAmplitude Venture CapitalAction Potential Venture Capital Ltd.ACORN BIOVENTURESCincyTechDe Novo VenturesSignet Healthcare PartnersWelsh, Carson, Anderson & StoweZetta Venture PartnersWildcat Venture PartnersM12 (Microsoft's Venture Fund)BDC Venture CapitalTencent HoldingsCofounders Capital+ND Capital

Firms observed investing alongside OrbiMed, from public investor directories. Shared companies are the overlap with OrbiMed's recorded portfolio.

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