/Investor DB

Longitude Capital

Growth equity

Menlo Park · Series A–Late Stage · 72 people tracked

Also known as LONGITUDE CAPITAL MANAGEMENT CO., LLC · Longitude Venture Partners

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Investment thesis

Longitude Capital pursues a venture growth strategy focused on biotechnology, medical technology, and health solutions companies working to improve clinical outcomes, enhance patient quality of life, and lower the cost of care. It builds a balanced portfolio of clinical-stage and commercial-stage companies with clinically de-risked assets, favorable valuations relative to risk, and expected returns within three to five years of initial investment. The firm invests in both private and public companies using varied structures including traditional venture capital, asset spin-outs, recapitalizations, PIPEs, open market purchases, and royalties. It sources opportunities via industry relationships and proprietary thematic research, then works closely with portfolio companies and syndicate partners to execute strategic plans and pursue liquidity.

Source: firm website, verified Sep 29, 2026.

Stage
Series A–Late Stage
Check
$10M – $30M
HQ
Menlo Park, CA, US
Leads rounds
Leads
Instruments
Equity
Founded
2006
Last 12 months
3 investments
AUM
$2.4B
Tracked investments
152
Unicorns
3
IPOs
20
Acquisitions
11

Team · 72 people

from the firm's website & curated & public directories
Irvin Akinseye· Associate

Founder mafia

2 people who came through Longitude Capital went on to found or lead other companies.

What they invest in

from 106 of 152 portfolio companies

Biotech ×66Healthtech ×65Medical Devices ×43Digital Health ×23AI & Machine Learning ×9Hardware ×9SaaS ×8Deep Tech ×5

HQs:United States×81Canada×1Switzerland×1Ireland×1Netherlands×1

Who they back

founder profiles across 54 portfolio companies
59%
solo founders
32 of 54 mapped founding teams
28%
repeat founders
of 39 founders with career history
~5 yrs
old at investment
median across 28 dated deals

Founding team size:solo founder×322 founders×143 founders×54+ founders×3

Where their founders studiedfrom 36 founders with education data

Harvard Medical School ×5Harvard University ×2UC Santa Barbara ×2University of New Hampshire ×2University of Wisconsin-Madison ×2

What their founders studiedfrom 37 founders with field-of-study data

Business & Management ×10Life Sciences ×10Engineering ×7Medicine ×7Computer Science ×6Chemistry ×3Finance & Accounting ×3Economics ×2

Where their founders worked beforefrom 39 founders with career history

AnaptysBio ×2Axonius ×2Harvard Medical School ×2Johnson & Johnson ×2Kleiner Perkins ×2

13 founders hold a PhD · 10 hold an MBA (of 41 with degree data)

Investments · 152 tracked

founders shown can be your intro path

By year:2026 · 32025 · 22024 · 72023 · 22022 · 42021 · 52020 · 42019 · 32018 · 82017 · 62015 · 32014 · 451 dated

Veradermicsveradermics.cominNYSE: MANE✓ verified

Veradermics is developing VDPHL01, an extended-release oral minoxidil tablet intended as a non-hormonal prescription treatment for pattern hair loss in women and men.

BiotechHealthtechWest Hartford, US

Reid Waldman(Chief Executive Officer and Board Member)inTim Durso(Chief Technical Officer)inDominic Carrano(Chief Financial Officer and Treasurer)inMark Neumann(Chief Commercial and Strategy Officer)John W. Childs(Director)Jane Grant-Kels(Director)

Co-investorsConnecticut InnovationsLifeSci Venture PartnersOUP (Osage University Partners)SR One Capital Managementabrdn plcInvus

Ceribellceribell.comin𝕏NASDAQ: CBLLSeries C · May 2021 · $53M

Ceribell is a medical technology company that develops products for detecting and monitoring seizures, including EEG-based diagnostic systems.

AI & Machine LearningDigital HealthHealthtechMedical DevicesSunnyvale, US

Josef Parvizi(Director)inXingjuan (Jane) Chao(President, CEO, Co-Founder & Director)inScott Blumberg(Executive Officer)inJoseph Taylor(Director)Raymond Woo(Executive Officer)David Stoffel(Executive Officer)

Board seatJuliet Tammenoms Bakker· per SEC Form D

Co-investorsRA CapitalRed Tree VentureShangBay Capital LLCThe Rise Fund

AEON Biopharmaaeonbiopharma.cominNYSE: AEON

AEON Biopharma develops botulinum toxin biosimilars and therapeutic neurotoxin treatments for patients with neuromuscular disorders.

BiotechHealthtechMedical Devices

Robert Bancroft(President, Chief Executive Officer and Director)John Bencich(Chief Financial Officer)inChad Oh(Chief Medical Officer)inAlex Wilson(Chief Legal & Strategy Officer; Corporate Secretary)inJennifer Sy(Chief Accounting Officer)in

BioAge Labsbioagelabs.comin𝕏NASDAQ: BIOAFeb 2024

BIOAGE develops therapies targeting the molecular pathways that drive aging to increase healthspan and address age-related chronic diseases.

BiotechHealthtechLongevityRichmond, US

Kristen Fortney, PhD(Co-Founder, CEO)Eric Morgen, MD(Co-Founder, COO)Kristen Fortney(Founder)inEric Morgen(Founder)inDov Goldstein(Executive Officer)in

BoardPatrick Enright(Director)in

Co-investorsAndreessen HorowitzElad GilFelicis VenturesGreen Sands EquityIA Seed VenturesOrbiMed+20 more

Boston Scientificbostonscientific.cominNYSE: BSXAcquired

Boston Scientific supports external researcher-initiated studies through its Investigator Sponsored Research program, which funds independent investigations addressing disease understanding and treatment gaps of interest to the medical community.

HealthtechMedical Devices

John Abele(Founder)inPeter Nicholas(Founder)Lance BatesinJonathan R. Monson(Executive Vice President and Chief Financial Officer)Miriam O'Sullivan(Senior Vice President, Chief Human Resources Officer)inMichael F. Mahoney(Chairman of the Board, President and Chief Executive Officer)

Co-investorsAndera PartnersCatalyst Health VenturesCouncilExcelestar VenturesGood Growth CapitalKleiner Perkins+8 more

CG Oncologycgoncology.comin𝕏NASDAQ: CGON

CG Oncology develops an investigational oncolytic immunotherapy for urologic cancer patients, specifically targeting BCG-unresponsive non-muscle invasive bladder cancer.

BiotechHealthtechMedical Devices

Arthur Kuan(Chairman and Chief Executive Officer)in

Co-investorsDecheng CapitalForesite CapitalPalm Drive CapitalRA CapitalTCG CrossoverACORN BIOVENTURES+3 more

Collegium Pharmaceuticalcollegiumpharma.comin𝕏NASDAQ: COLL

Collegium Pharmaceutical is a biopharmaceutical company developing a portfolio of medications to treat serious medical conditions.

BiotechCanton, US

Michael Heffernan(Executive Officer, Director)inPaul Brannelly(Executive Officer)inVikram Karnani(President and Chief Executive Officer, and Director)in

BoardEran Nadav(Director)John Freund(Director)Patrick Heron(Director)in

Co-investorsAPERTURE Venture PartnersEcoR1 CapitalFrazier Life SciencesBoston Millennia PartnersRA Capital

Corcept Therapeuticscorcept.cominNASDAQ: CORT

Corcept develops cortisol modulators — molecules that regulate cortisol activity at the glucocorticoid receptor — to treat serious diseases across endocrinology, oncology, metabolism, and neurology.

AI & Machine LearningBiotechHealthtechMedical Devices

Joseph K. Belanoff(Chief Executive Officer and President)

Co-investorsMountain Group CapitalRidgeback Capital

CytomX Therapeuticscytomx.comin𝕏NASDAQ: CTMX

CytomX is a clinical-stage biopharmaceutical company developing conditionally activated biologic cancer therapies, including antibody-based treatments designed to target tumors while limiting effects on healthy tissue.

BiotechHealthtechSouth San Francisco, US

Sean A. McCarthy(Chief Executive Officer and Chairman)inMarcia P. Belvin(SVP, Chief Scientific Officer)inDawn Benson(SVP, Quality and Product Manufacturing)inWayne Chu(Chief Medical Officer)Rachael Lester(SVP, Chief Business Officer)inChris Ogden(Chief Financial Officer)in

Co-investorsATEL VenturesCanaan PartnersPfizer Venture InvestmentsWellington ManagementOrbiMedThird Rock Ventures

KALA BIOkalarx.cominNASDAQ: KALA

A biopharmaceutical company developing an artificial intelligence infrastructure platform designed for on-premises deployment in biotechnology and pharmaceutical research environments, serving biotech firms and pharma companies seeking secure access to advanced AI capabilities while retaining control over proprietary biological data; the company is also evaluating strategic alternatives for its legacy mesenchymal stem cell secretome assets after discontinuing its lead rare eye disease therapeutic program.

BiotechArlington, US

Justin Hanes(Director)inKevin Pojasek(Executive Officer)inDarius Kharabi(Executive Officer)inTodd Bazemore(Executive Officer)inMark Iwicki(Executive Officer, Director)inMary Reumuth(Executive Officer)in

Co-investorsSR One Capital ManagementWellington ManagementYsios CapitalAtlas VentureLux CapitalRA Capital+1 more

Kestra Medical Technologieskestramedical.cominNASDAQ: KMTSJul 2024 · $200M

Kestra Medical Technologies develops wearable medical devices and digital healthcare solutions designed for collaborative care between providers and patients.

Digital HealthHardwareHealthtechMedical Devices

Brian Webster(President, Chief Executive Officer, and Director)inTraci S. Umberger(General Counsel, Chief Administrative Officer, and Director)inVaseem Mahboob(Chief Financial Officer)inAl Ford(Chief Commercial Officer)inTimothy Moran(Chief Business Officer)

Co-investorsAndera PartnersBain Capital Life SciencesStar51 CapitalBain Capital

MicroTranspondermicrotransponder.com𝕏NASDAQ: MOBI

Mobia Medical (formerly MicroTransponder) develops Vivistim Paired VNS Therapy, an FDA-approved treatment for stroke survivors with moderate to severe upper extremity impairment.

Digital HealthHealthtechMedical DevicesAustin, US

Richard John Foust(Executive Officer, Director)Frank McEachern(Executive Officer, Director)in

BoardNelson Bunker Curnes(Executive Officer, Director)Thomas Jordan Curnes II(Executive Officer, Director)Casey Tansey(Director)Dana Mead(Director)

Co-investorsUT Horizon FundGreen Park & Golf VenturesUS Venture Partners

Mirum Pharmaceuticalsmirumpharma.comin𝕏NASDAQ: MIRM

Mirum Pharmaceuticals is a biopharmaceutical company that develops and delivers therapies for people living with rare diseases.

BiotechHealthtechSan Diego, US

Chris Peetz(Co-founder & Chief Executive Officer)inEric Bjerkholt(Executive Officer)inPeter Radovich(Executive Officer)in

BoardPatrick Heron(Director)inMichael Grey(Director)Timothy Walbert(Director)

Co-investorsChiesi VenturesFrazier Life SciencesMESA VERDE VENTURE PARTNERSNew Enterprise Associates (NEA)Pappas CapitalRiverVest Venture Partners+4 more

PROCEPT BioRobotics Corpprocept-biorobotics.comNASDAQ: PRCT

PROCEPT BioRobotics develops robotic-assisted surgical technology for men's health, focused on treating benign prostatic hyperplasia (BPH).

HealthtechMedical DevicesRoboticsRedwood City, US

Nikolai Aljuri, Ph.D.(Executive Officer, Director)Larry L. Wood(President, Chief Executive Officer & Director)Kevin Waters(EVP, Chief Financial Officer)inAlaleh Nouri(EVP, Chief Legal Officer & Corporate Secretary)in

BoardFred Moll(Director)inColby Wood(Director)

Co-investorsSonder CapitalViking GlobalSonder Futures

Rapid Micro BiosystemsNASDAQ: RPID

Rapid Micro Biosystems manufactures automated laboratory testing systems and consumables for pharmaceutical and cell therapy manufacturers to conduct microbiological quality control testing, replacing manual methods with platform-based analysis.

HealthtechLowell, US

Robert Spignesi(Executive Officer, Director)inStephen H. Delity(Executive Officer, Director)Michael J. Mullen(Executive Officer)

BoardDavid Hirsch(Director)Richard S. Kollender(Director)Fred Cohen(Director)

Co-investorsEndeavour VisionKleiner PerkinsXeraya CapitalAlly Bridge Group

Rxsightrxsight.comin𝕏NASDAQ: RXSTJun 2015 · $52M

RxSight develops the Light Adjustable Lens (LAL), an FDA-approved intraocular lens that surgeons can adjust after cataract surgery to fine-tune a patient's prescription once the eye has healed.

HealthtechMedical DevicesPasadena, US

Robert H. Grubbs(Director)Daniel M. Schwartz(Director)D. Verne Sharma(Executive Officer, Director)Richard Drinkward(Executive Officer)inRon Kurtz(President, Chief Executive Officer & Director)Mark Wilterding(Chief Financial Officer)in

Co-investorsFlying L PartnersForesite CapitalH.I.G. CapitalH.I.G. HealthBridge PartnersRA CapitalVisionary Ventures+2 more

SUTROVAX, INC.sutrovax.comNASDAQ: PCVX

Vaxcyte is a biotech company developing vaccines to treat or prevent serious infectious diseases.

BiotechDeep TechHealthtechSouth San Francisco, US

Grant Pickering(Chief Executive Officer, Director and Co-Founder)Jeff Fairman(Vice President of Research and Co-Founder)Ashish Khanna(Executive Officer)

BoardTracy Saxton(Director)William Newell(Director)Kurt von Emster(Director)in

Co-investorsAbingworthCTI Life Sciences Fund L.P.Foresite CapitalFrazier Life SciencesJanus Henderson InvestorsMedicxi+4 more

Vaxcytevaxcyte.comNASDAQ: PCVX

Vaxcyte develops broad-spectrum vaccines to prevent bacterial infections, using a cell-free protein synthesis platform and synthetic chemistry techniques.

BiotechHealthtech

Grant Pickering(Founder)in

Co-investorsBioRock VenturesCTI Life Sciences Fund L.P.Foresite CapitalFrazier Life SciencesPivotal Life SciencesRA Capital+3 more

Veratxveratx.comin𝕏NASDAQ: VERAOct 2020

Vera Therapeutics develops medicines targeting autoimmune-driven kidney diseases, with a focus on reducing the need for dialysis or transplant.

BiotechDigital HealthMedical DevicesSouth San Francisco, US

Marshall Fordyce(Executive Officer, Director)in

BoardBeth Seidenberg(Director)inMaha Katabi(Director)inKurt von Emster(Director)inPatrick Enright(Director)inAndrew Cheng(Director)

Co-investorsKleiner PerkinsSofinnova VenturesAbingworthSofinnova Venture Partners

Zenas Biopharmazenasbio.cominNASDAQ: ZBIO

Zenas BioPharma is a biopharmaceutical company developing therapies for autoimmune diseases, with two late-stage drug candidates: obexelimab, a bifunctional monoclonal antibody targeting CD19 and FcγRIIb to suppress B cell activity, and orelabrutinib, an oral BTK inhibitor.

BiotechHealthtechWaltham, US

LEON O. MOULDER, JR.(Director)Lonnie Moulder(Founder)JOSEPH FARMER(Executive Officer)HUA MU(Executive Officer, Director)in

BoardPATRICK GERALD ENRIGHT(Director)inHONGBO LU(Director)

Co-investorsDelos CapitalNew Enterprise Associates (NEA)Norwest Venture PartnersPivotal Life SciencesQuan CapitalSR One Capital Management+3 more

Alentis Therapeuticsalentis.chin✓ verified

Alentis is a biotech company developing therapies for chronic liver disease, fibrosis, and cancer based on the molecular biology of liver disease.

AI & Machine LearningBiotechHealthtechMedical DevicesBasel, CH

Thomas Baumert(Founder)inMark Pruzanski(Chief Executive Officer)inLuigi Manenti(Chief Medical Officer)inJon Freve(Chief Financial Officer)inBryan Yoon(General Counsel and Chief Administrative Officer)inAditya Venugopal(Chief Business Officer)in

Co-investorsAvego BioScience CapitalBioMedPartnersFrazier Life SciencesJeito CapitalNovo HoldingsOrbiMed+5 more

Aviceda Therapeuticsavicedarx.comin𝕏✓ verified

Biotechnology company developing immunomodulators using a HALOS nanotechnology platform for chronic inflammation.

BiotechDigital HealthHealthtechMedical DevicesCambridge, US

Michael Tolentino(Executive Officer, Director)inMohamed A. Genead(Chairman & CEO)inDavid Callanan(Executive Officer)inDerek Kunimoto(Executive Officer)inJeffrey Nau(Chief Executive Officer)inTarek S. Hassan(Chief Development Officer)in

Co-investorsJeito CapitalCatalio Capital Management, LPOrbiMedAvoro Capital AdvisorsDigitalis VenturesOmega Funds

CuraSen Therapeuticscurasen.cominOct 2018✓ verified

CuraSen Therapeutics is a privately funded biopharmaceutical company developing treatments that selectively activate adrenergic receptors in the brain to restore noradrenergic signaling.

BiotechHealthtechSan Carlos, US

Anthony Ford(Executive Officer, Director)inBenjamin Potter(Executive Officer)Henry Skinner(Director)Liam Ratcliffe(Director)in

BoardRon Hunt(Director)inLoretta Tse, Ph.D.(Director)

Co-investorsAlta Partnersabrdn plcIntermediate Capital GroupJohnson & Johnson Innovation – JJDCNew Leaf Venture PartnersPappas Capital+2 more

OrsoBioorsobio.comin𝕏Nov 2023 · $60M✓ verified

OrsoBio develops therapies to restore energy homeostasis in patients with severe metabolic disorders, drawing on biological research including human liver organoids and insights from metabolic pathways.

BiotechDeep TechMedical DevicesMenlo Park, US

Mani Subramanian(Executive Officer, Director)inGangadhara Ganapati(Executive Officer, Director)Dr. SubramanianDr. Myers

BoardMatthew Young(Director)inSrinivas Akkaraju(Director)

Co-investorsAscenta CapitalSamsara BioCapitalF-Prime Capital

Sydnexissydnexis.comin✓ verified

Sydnexis is a privately held biopharmaceutical company developing SYD-101, a proprietary low-dose atropine formulation in Phase 3 clinical trials to slow the progression of pediatric progressive myopia.

BiotechDigital HealthDel Mar, US

Patrick Johnson(Executive Officer, Promoter)inMary Jaqueline Johnson(Executive Officer)Mary Jacqueline Johnson(Executive Officer)Kevin Johnson(Director)Greg Ostrow(Executive Officer, Director)Kenneth Widder(Executive Officer, Director)

Co-investorsRA CapitalVisionary Ventures

Axonics Modulation Technologiesaxonics.cominApr 2017 · $20M

Boston Scientific develops medical devices and technologies used by healthcare professionals to treat patients across a range of conditions.

HealthtechMedical DevicesIrvine, US

Michael Williamson(Executive Officer)Dan L. Dearen(Executive Officer)inRaymond Cohen(Executive Officer, Director)in

BoardDarren Cai(Director)Raphael Wisniewski(Director)Erik Amble(Director)

Board seatMs. Bakker· per SEC Form D

Co-investorsAdvent Life SciencesAndera PartnersGilde Healthcare

Venus Conceptvenusconcept.comin𝕏Nov 2019 · $10M

Venus develops non-invasive, energy-based medical aesthetic devices for body, face, skin, and hair treatments, integrating robotics, AI, and IoT technologies.

BiotechHardwareHealthtechMedical DevicesToronto, US

Domenic Serafino(Executive Officer, Director)inKirk Gunhus(Executive Officer)inRoss Portaro(Executive Officer)inAnna Georgiadis(Executive Officer)inMelissa Kang(Executive Officer)inMichael Mandarello(Executive Officer)in

Board seatMs. Bakker· per SEC Form D

Co-investorsAPERTURE Venture PartnersEssex Woodlands Healthcare PartnersClarus VenturesHealthQuest Capital

89bio (NASDAQ: ETNB)89bio.cominacquired by Roche · Sep 2025

A clinical-stage biopharmaceutical company developing investigational therapies for patients with liver and cardiometabolic diseases, with a lead candidate (pegozafermin) being evaluated for metabolic dysfunction-associated steatohepatitis and severe hypertriglyceridemia.

BiotechHealthtechMedical DevicesSan Francisco, US

Rohan Palekar(Founder)in

Co-investorsK2 HealthVenturesRA Capital

Aimmune Therapeuticsaimmune.comAcquired

Aimmune Therapeutics developed desensitization treatments for life-threatening food allergies, including Palforzia, the first FDA-approved peanut allergy treatment.

Co-investorsAisling CapitalForesite CapitalMenlo Ventures

AirNexis Therapeuticsairnexis.cominJan 2026

Clinical-stage biopharmaceutical company developing novel inhaled therapies for COPD.

BiotechPalo Alto, US

James Li(Executive Officer, Director)Maria Fardis(Executive Officer, Director)in

BoardAnna Chen(Director)Colin Walsh(Director)Evan Caplan(Director)Jill Carroll(Director)in

Co-investorsFrazier Life SciencesOrbiMedSR One Capital Management

Akebia Therapeuticsakebia.comin𝕏

Akebia Therapeutics develops FDA-approved drug therapies for the treatment of kidney disease.

BiotechHealthtechMedical DevicesCambridge, US

John P. Butler(President and Chief Executive Officer)in

Co-investorsCincyTech

Alpha-9 Oncologya9oncology.cominOct 2024

Alpha-9 Oncology develops radiopharmaceuticals for cancer treatment, with a portfolio of molecules in clinical and preclinical development.

BiotechDigital HealthMedical DevicesVancouver, CA

François Bénard(Founder)Kuo-Shyan Lin(Founder)David Perrin(Founder)

Co-investorsAndreessen HorowitzAscenta CapitalDelos CapitalFrazier Life SciencesGeneral CatalystLightspeed Venture Partners+9 more

Alpha-9 Theranostics Inc.alpha9tx.cominApr 2021

Alpha-9 is a clinical-stage radiopharmaceutical company developing a portfolio of targeted molecules to treat cancer cells with precision.

BiotechLongevityMedical Devices

Co-investorsFrazier Life SciencesWUTIF CapitalAscenta CapitalBiotechnology Value FundLightspeed Venture PartnersNextech Invest+1 more

Amarinamarincorp.comin𝕏

Amarin Corporation is a cardiovascular health pharmaceutical company developing treatments to prevent cardiovascular disease.

BiotechHealthtechMedical Devices

Co-investorsAvoro Capital AdvisorsFountain Healthcare PartnersSignet Healthcare PartnersSofinnova Ventures

Amphoraamphoralogistics.cominJul 2017 · $35.5M

Amphora provides logistics services aimed at supporting business growth and operational efficiency.

E-commerceLogistics & Supply ChainSaaS

Joan Tresserras(Founder)inAdrià Cortés(Founder)in

Co-investorsBStartupBaird CapitalF-Prime CapitalHBM Healthcare Investments

Amunix Pharmaceuticalsamunix.comMar 2020 · $73M

Biopharmaceutical company discovering and developing novel biologics, protein, and peptide therapeutics.

South San Francisco, US

Co-investorsBain Capital Life SciencesFrazier Life SciencesViking GlobalBlackRockCasdin CapitalFranklin Templeton+6 more

Aptinyxaptinyx.com

BiotechEvanston, US

Joseph R. Moskal(Chief Scientific Officer)Torsten M. Madsen(Chief Marketing Officer)Ashish Khanna(Secretary & Chief Business Officer)Norbert G. Riedel(Chief Executive Officer)

BoardLiam Ratcliffe(Director)Terry P. Gould(Director)

Co-investorsBain Capital Life SciencesFrazier Life SciencesLatterell Venture PartnersOUP (Osage University Partners)Agent CapitalBain Capital+3 more

Aptus Endosystemsin𝕏acquired by Medtronic · Jun 2015 · $110M

Aptus Endosystems developed endovascular devices, including the Heli-FX EndoAnchor systems, that use helical anchors to secure stent-grafts during minimally invasive aortic aneurysm repair.

HealthtechMedia & EntertainmentMedical Devices

Co-investorsUS Venture Partners

Assembly Biosciencesassemblybio.comin

Assembly Bio is a biopharmaceutical company developing novel therapeutic candidates for viral and liver diseases, including programs targeting herpesviruses, hepatitis delta virus, hepatitis B virus, and cholestatic liver diseases.

BiotechHealthtechMedical Devices

Jason Okazaki(Chief Executive Officer & President)inWilliam Delaney, PhD(Chief Scientific Officer)Anuj Gaggar, MD, PhD(Chief Medical Officer)

Co-investorsAvoro Capital Advisors

Avenge Bioavengebio.comJan 2022 · $45M

Biotechnology company developing the LOCOcyte cell-therapy platform for local dosing of immunotherapeutics.

Co-investorsPappas CapitalPerceptive Xontogeny VentureRock Springs Capital

Axonicsaxonicsmodulation.comin

Axonics Modulation, now part of Boston Scientific, develops medical devices in the field of neuromodulation therapies for patients.

HealthtechMedical Devices

Raymond Cohenin

Co-investorsAPERTURE Venture PartnersGilde Healthcare

BAROnova, Inc.baronova.comin

Non-surgical, non-pharmacologic devices to induce weight loss

Co-investorsDelos CapitalArboretum VenturesHighland Capital PartnersSante Ventures

Bina health-beautyin𝕏

BiotechHealthtechMedical Devices

Co-investorsSGH CapitalSunstone Capital

Bolt Medicalboltmed.comin

Bolt Medical develops the Bolt IVL intravascular lithotripsy system, a laser-based balloon catheter platform that fractures arterial calcium using acoustic pressure waves to treat coronary and peripheral artery disease.

HardwareHealthtechMedical DevicesMarlborough, US

Co-investorsBeyond Next Ventures

Campfieldtxcampfieldtx.comin

cAMPfield is a clinical-stage biopharmaceutical company developing prifemilast, a once-daily oral PDE4B-selective inhibitor for immune-mediated inflammatory diseases, primarily inflammatory bowel disease (ulcerative colitis and Crohn's disease).

BiotechHealthtech

Graham Heap(President, Research and Development)inEzequiel Neimark(Head of Clinical Development)inTaylor Spector(Head of Medical Affairs)inScott Stirn(Head of CMC)in

Co-investorsFrazier Life Sciences

Cardiodxin

Molecular diagnostics company commercializing tools for diagnosing cardiovascular disease.

BiotechRedwood City, US

Mark Monane(Executive Officer)Gwen R. Carscadden(Executive Officer)David L. Levison(Executive Officer, Director)Deborah L. Kilpatrick(Executive Officer)inRobert F. Werner(Executive Officer)Douglas T. Ross(Executive Officer)

Co-investorsPappas Capital

Checkmate Pharmaceuticalscheckmatepharma.comAcquired

Activating the immune system to recognize and destroy tumor cells.

BiotechCambridge, US

Art Krieg(Executive Officer, Director)Barry Labinger(Executive Officer, Director)Chuck Abdalian(Executive Officer)David Mauro(Executive Officer)Karen Brennan(Executive Officer)Charles Yon(Executive Officer)

Co-investorsDecheng CapitalF-Prime CapitalSofinnova VenturesNovo HoldingsvenBio Partners

Civitas Therapeuticscivitastherapeutics.comAug 2014 · $20M

BiotechChelsea, US

RICHARD BATYCKY(Executive Officer)GLENN BATCHELDER(Director)BRYAN STUART(Executive Officer)inMARK IWICKI(Executive Officer, Director)inMARTIN FREED(Executive Officer)in

BoardROB HOPFNER(Director)in

Co-investorsCanaan PartnersSofinnova VenturesBay City CapitalFountain Healthcare PartnersOrbiMedRA Capital

Cohere Healthcoherehealth.cominFeb 2024 · $50M

Cohere Health provides a platform aimed at aligning the interests of patients, physicians, and health plans to support care decisions and improve member outcomes.

AI & Machine LearningDigital HealthEnterprise SoftwareHealthtechSaaSBoston, US

Siva Namasivayam(Executive Officer, Director)inRobert Shepardson(Executive Officer)inKristen Carucci(Executive Officer)inDuncan Reese(Executive Officer)

BoardDavid Barrett(Director)Amir Debourou(Director)

Co-investorsCota CapitalFlare Capital PartnersDeerfield Management CompanyDefine VenturesFlare Capital StrategiesPolaris Partners+1 more

Cohere Technologiescohere-technologies.comin𝕏

Cohere Technologies develops software for mobile and wireless networks, including its Universal Spectrum Multiplier (USM) for 4G and 5G and Pulsone technology based on the Zak-OTFS waveform, aimed at Mobile Network Operators.

AI & Machine LearningCloud ComputingDeep TechDefense TechEnterprise SoftwareHardwareSanta Clara, US

Shlomo Rakib(Executive Officer, Director)in

BoardRon Bernal(Director)inKrishna Kolluri(Director)Chris Schaepe(Director)

Co-investorsLightspeed Venture PartnersNew Enterprise Associates (NEA)Bell VenturesIntel CapitalJuniperKoch Disruptive Technologies+3 more

Corticacorticacare.comin

Cortica provides in-home, in-clinic, and telehealth neurological therapies for children with autism and developmental differences, integrating neurological, biomedical, behavioral, speech-language, and sensorimotor treatments.

Digital HealthHealthtechMedical DevicesSan Diego, US

Dr. Suzanne Goh(Founder)Neil Hattangadi(Founder)inBriana Elvaiah(Executive Officer)inSuzanne Goh-Hattangadi(Founder)

BoardRyan Drant(Director)inStephen Anastos(Director)

Co-investors.406 VenturesAIFAPERTURE Venture PartnersCVS Health VenturesEcho Health VenturesOptum Ventures+6 more

CrownWheel Partners, LLCcrownwheelpartners.com

JAN46 is an online gaming platform offering game top-ups (in-game credits/items) with automated delivery, along with esports tournaments featuring live brackets and streaming, and player community tools.

ConsumerGaming

CV Therapeuticsgilead.comin𝕏

Gilead discovers, develops, and delivers innovative therapeutics for people with life-threatening diseases, focusing on virology, oncology, and inflammation across more than 35 countries.

BiotechDigital HealthHealthtechMedical DevicesFoster City, US

Lou Lange(Founder)Michael L. Riordan(Founder)inDaniel O'Dayin

Co-investorsAisling CapitalAsset Management CompanyFrazier Life SciencesKleiner PerkinsLumira VenturesMenlo Ventures+5 more

Eargoeargo.comDec 2018 · $82MDefunct

Eargo was a hearing aid company that provided high-quality hearing aids and related care services.

HealthtechMedical DevicesMountain View, US

Raphael Michel(Founder)Christian Gormsen(Executive Officer, Director)William Brownie(Executive Officer)Peter Tuxen Bisgaard(Director)Daniel Shen(Founder)Florent Michel(Founder)

Co-investorsBirchmere VenturesDolby Family VenturesMaveronNew Enterprise Associates (NEA)Peterson VenturesCrosslink Capital+4 more

Endeavor Biomedicinesendeavorbiomedicines.comin𝕏

Endeavor BioMedicines is a biopharmaceutical company developing medicines aimed at treating patients with serious, intractable diseases, with the goal of altering disease progression rather than only slowing it.

BiotechSan Diego, US

John Hood(Co-Founder, Chief Executive Officer & Executive Chairman)inWing Cheong Lam(Director)Bernard Davitian(Director)Raghu Saripalli(Executive Officer)Monal Mehta(Director)inMiguel de los Rios(Co-Founder & Chief Scientific Officer)in

Co-investorsFidelity InvestmentsOmega Funds

Endogenexendogenex.comin𝕏Series C · Jun 2024 · $88M

Endogenex is a clinical-stage medical device company developing the pulsENDO system, which applies non-thermal pulsed electric field to reset the body's metabolic signaling and improve function in people with type 2 diabetes.

Digital HealthHealthtechMedical DevicesMinneapolis, US

Stacey Pugh(Leadership (CEO))inChris Sorli, MD, PhD(Chief Medical Officer)inKrissy Wright(Chief Financial Officer)inLian Cunningham, MD, PhD(VP Clinical Affairs)inMelanie Hess(Regulatory Affairs Leadership)inMatt Cambronne(Technical/Engineering Leadership)in

Co-investorsArboretum VenturesHatteras Venture PartnersIntuitive VenturesLumira VenturesSoutheast Minnesota Capital Fund

Epirium Bioepirium.comDec 2019 · $85M

Epirium Bio develops novel oral therapeutics targeting mitochondrial dysfunction and muscle diseases, particularly muscular dystrophy.

BiotechMedical DevicesSan Diego, US

Pam Taub(M.D., FACC, Founder)Alan Maisel(M.D., Founder)Francisco Villarreal(M.D., Ph.D., Founder)Jonathan Taub(Co-founder and first Chief Executive Officer)Guillermo Ceballos(M.D., Founding Scientist)Pam Taub, M.D., FACC(Co-founder)

Co-investorsBluebird VenturesBroadview VenturesAdams Street PartnersARCH Venture PartnersVertex VenturesVertex Ventures HC

Esperion Therapeuticsesperion.comJun 2014

Biopharma developing HDL-C regulating therapies; listed 2000.

BiotechAnn Arbor, US

Roger S. Newton(Director)inTim M. Mayleben(Executive Officer, Director)

BoardDaniel Janney(Director)Dov A. Goldstein(Director)Nicole Vitullo(Director)inPatrick Enright(Director)in

Co-investorsAisling CapitalAlta PartnersArboretum VenturesARCHIMED JapanAsset Management CompanyCanaan Partners+3 more

FIRE1fire1foundry.comin𝕏Jan 2025 · $120M

FIRE1 develops NORM, an implantable sensor placed in the inferior vena cava to directly measure fluid volume in heart failure patients, paired with a self-management platform to help patients engage with their own care.

Digital HealthHardwareMedical DevicesDublin, IE

Co-investorsAndera PartnersGimvIreland Strategic Investment FundLightstone VenturesNew Enterprise Associates (NEA)Seventure Partners+5 more

Generate Life Sciencesgenerate.comin

Generate Life Sciences was a reproductive, newborn stem cell, and genetic services company offering products and services to help families grow and protect their families.

BiotechDigital HealthHealthtech

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

Alphaeon89BioAimmuneAllergen ResearchAmphora MedicalAqueSysCadenceCadence PharmaceuticalscAMPfieldcAMPfield TherapeuticsCardero TherapeuticsCivitasCohereCollegiumCorceptCydanCydan DevelopmentCydan IIDascenaEncore DermatologyEsperionGcs WebInfaCareInfacare PharmaceuticalInflazomeKaNDyKaNDy TherapeuticsKestra Medical TechnologyLexeo TherapeuticsNeuranaNeurana PharmaceuticalsNxStageOn BelayOrbusPixelOpticsPoseidaPrecision DermatologyPrecision TherapeuticsRapidmicrobioRenewSoltaSublimity TherapeuticsSymparaTwelveVelomedixVera TherapeuticsXanodyneXeris Biopharma

Exits · 31

20 IPOs · 11 acquisitions · showing 28

VeradermicsNYSE: MANECeribellNASDAQ: CBLLAEON BiopharmaNYSE: AEONBioAge LabsNASDAQ: BIOABoston ScientificNYSE: BSXCG OncologyNASDAQ: CGONCollegium PharmaceuticalNASDAQ: COLLCorcept TherapeuticsNASDAQ: CORTCytomX TherapeuticsNASDAQ: CTMXKALA BIONASDAQ: KALAKestra Medical TechnologiesNASDAQ: KMTSMicroTransponderNASDAQ: MOBIMirum PharmaceuticalsNASDAQ: MIRMPROCEPT BioRobotics CorpNASDAQ: PRCTRapid Micro BiosystemsNASDAQ: RPIDRxsightNASDAQ: RXSTSUTROVAX, INC.NASDAQ: PCVXVaxcyteNASDAQ: PCVXVeratxNASDAQ: VERAZenas BiopharmaNASDAQ: ZBIO89bio (NASDAQ: ETNB)acq. by RocheAmphora Medicalacq. by HologicAptus Endosystemsacq. by MedtronicHelomicsacq. by Predictive OncologyLumena Pharmaceuticalsacq. by ShireNxStage Medicalacq. by Fresenius Medical CarePentec Health Celebrates 35th Anniversaryacq. by Wellspring Capital ManagementThumbnail for Constellation Pharmaceuticalsacq. by MorphoSys

Portfolio news

latest coverage across their companies

Fund performance · per public LP disclosures

as of Jun 2025
FundVintageCommittedNet IRRTVPIDPI
Longitude Venture Partners IIILPs: Los Angeles City Employees' Retirement System, Maryland State Retirement and Pension System2016—16.8%1.68x0.96x

Source: public limited-partner disclosures (CalPERS, CalSTRS). Net IRR / TVPI / DPI as reported by the limited partner; a fund's early-year IRR is an interim estimate (J-curve).

IPO stake values · per SEC filings · 7

Value of this firm's stake in each portfolio company at its IPO price, from the prospectus principal-stockholder table.

CompanyOwnedIPO priceAt IPOStake value
Veradermics11.3%$100.00Apr 2026$465.4M
CG Oncology6.2%$28.00Dec 2024$130.5M
Veratx11.9%$15.00Feb 2022$46.4M
Ceribell7.3%$17.00Oct 2024$42.1M
Zenas Biopharma5.2%$17.00Sep 2024$35.1M
KALA BIO8.8%$15.00Jul 2017$30.8M
BioAge Labs3.8%$18.00Sep 2024$23.6M

Source: SEC S-1 / 424B prospectus filings. Stake value = shares beneficially owned × the initial public offering price, as disclosed — a market value at IPO, not a return multiple (the firm's original cost is not disclosed).

Public market activity · per SEC filings

what is this? ⓘ

2 insider ownership filings (Forms 3/4/5)

at Veradermics, Inc (MANE)

From the firm's own SEC EDGAR filings — stakes and insider roles in public companies, typically portfolio companies after an IPO. Not a portfolio list published by the firm.

Frequently asked questions

How many investments has Longitude Capital made?
Longitude Capital has 152 tracked investments, 31 of which have exited, including 6 dated in the last 24 months.
What stage does Longitude Capital invest at?
Longitude Capital invests at the Series A, Series B, Series C, Growth, Late Stage stages.
What is Longitude Capital's typical check size?
Longitude Capital typically writes checks of $10M – $30M.
What sectors does Longitude Capital focus on?
Longitude Capital focuses on Biotech, Digital Health, Healthtech, Longevity, Medical Devices.
Where is Longitude Capital located?
Longitude Capital is headquartered in Menlo Park, US.
Does Longitude Capital lead rounds?
Yes, Longitude Capital leads investment rounds.
Who does Longitude Capital co-invest with?
Longitude Capital most often shares deals with Frazier Life Sciences, RA Capital, New Enterprise Associates (NEA), among 211 tracked co-investors.

Co-investors · 6

Pivotal Life Sciences

Pivotal Life Sciences is a global healthcare investment firm backing companies developing high-impact therapeutics for major unmet medical needs, operating across venture capital, venture building, and public equity strategies.

Menlo Ventures

Menlo Ventures is an early-stage venture capital firm backing transformative technology companies, with a strong current emphasis on artificial intelligence across enterprise, healthcare, and consumer markets.

Both backed · 3
$1M – $20M
Bain Capital

Bain Capital is a global private investment firm operating across private equity, growth and venture, credit, real assets, and capital solutions, partnering with companies to create value across sectors and regions.

Vensana Capital

Vensana Capital is a venture capital and growth equity investment firm focused on partnering with entrepreneurs building breakthrough medical technology innovations to transform healthcare.

Longwood Fund

Longwood Fund is a venture capital firm that creates and invests in novel healthcare companies developing new treatments for patients, drawing on its partners' company-building and operating experience.

Both backed · 1

Firms observed investing alongside Longitude Capital, from public investor directories. Shared companies are the overlap with Longitude Capital's recorded portfolio.

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