🦊/Investors

Longitude Capital

Growth equity

Menlo Park · Series A–Late Stage · 78 people tracked

Also known as LONGITUDE CAPITAL MANAGEMENT CO., LLC · Longitude Venture Partners

Find your way into Longitude Capital

598 people in our graph share verified history with the Longitude Capital team — schools, employers, funds. One of them is your warm intro.

Mike Volpiunlockedknows Patrick Enright · together at Stanford University (overlapped)
×5knows the team · via Stanford University
×2knows the team · via Princeton University
knows the team · via Northwestern University - Kellogg School of Management
knows the team · via Rothstein Kass
×2knows the team · via Pequot Capital
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Investment thesis

Invests in mid- to commercial-stage biotech and medtech with clinically de-risked assets, using spin-outs, recapitalizations, PIPEs and other structured transactions, and sources deals via its academic research network.

Source: firm website, verified Sep 15, 2026.

Stage
Series A–Late Stage
Check
$10M – $30M
HQ
Menlo Park, CA, US
Leads rounds
Leads
Instruments
Equity
Founded
2006
Last 12 months
2 investments
AUM
$2.4B
Tracked investments
107
Unicorns
2
IPOs
17
Acquisitions
9

Team · 78 people

from the firm's website & curated & public directories
Irvin Akinseye· Associate

What they invest in

from 92 of 107 portfolio companies

Biotech ×60Healthtech ×58Medical Devices ×38Digital Health ×23Hardware ×8AI & Machine Learning ×7SaaS ×6Deep Tech ×3

HQs:United States×68Canada×1Switzerland×1Ireland×1Netherlands×1

Who they back

founder profiles across 40 portfolio companies
57%
solo founders
23 of 40 mapped founding teams
29%
repeat founders
of 34 founders with career history
~5 yrs
old at investment
median across 18 dated deals

Founding team size:solo founder×232 founders×133 founders×24+ founders×2

Where their founders studiedfrom 32 founders with education data

Harvard Medical School ×4Harvard University ×2The Tuck School of Business at Dartmouth ×2UC Santa Barbara ×2University of New Hampshire ×2University of Wisconsin-Madison ×2

What their founders studiedfrom 28 founders with field-of-study data

Business & Management ×8Life Sciences ×7Medicine ×6Engineering ×4Chemistry ×3Computer Science ×3Finance & Accounting ×2

Where their founders worked beforefrom 34 founders with career history

AnaptysBio ×2Evolve Biosystems ×2Harvard Medical School ×2Johnson & Johnson ×2Kleiner Perkins ×2McKinsey & Company ×2

12 founders hold a PhD · 7 hold an MBA (of 31 with degree data)

Investments · 107 tracked

founders shown can be your intro path

By year:2026 · 22025 · 22024 · 72023 · 22022 · 32021 · 42020 · 32019 · 32018 · 22017 · 52015 · 32014 · 339 dated

Veradermicsveradermics.cominNYSE: MANE✓ verified

Veradermics is developing VDPHL01, an extended-release oral minoxidil tablet intended as a non-hormonal prescription treatment for pattern hair loss in women and men.

BiotechHealthtechWest Hartford, US

Reid Waldman(Chief Executive Officer and Board Member)inTim Durso(Chief Technical Officer)inDominic Carrano(Chief Financial Officer and Treasurer)inMark Neumann(Chief Commercial and Strategy Officer)John W. Childs(Director)Jane Grant-Kels(Director)

Co-investorsConnecticut InnovationsOUP (Osage University Partners)SR One Capital Managementabrdn plcInvusLifeSci Venture Partners

Ceribellceribell.comin𝕏NASDAQ: CBLLSeries C · May 2021 · $53M

Ceribell is a medical technology company that develops products for detecting and monitoring seizures, including EEG-based diagnostic systems.

AI & Machine LearningDigital HealthHealthtechMedical DevicesSunnyvale, US

Josef Parvizi(Director)inXingjuan (Jane) Chao(President, CEO, Co-Founder & Director)inScott Blumberg(Executive Officer)inJoseph Taylor(Director)Raymond Woo(Executive Officer)David Stoffel(Executive Officer)

Board seatJuliet Tammenoms Bakker· per SEC Form D

Co-investorsRA CapitalRed Tree VentureShangBay Capital LLCThe Rise Fund

Aeonbiopharmaaeonbiopharma.cominNYSE: AEON

AEON Biopharma develops botulinum toxin biosimilars and therapeutic neurotoxin treatments for patients with neuromuscular disorders.

BiotechHealthtechMedical Devices

Robert Bancroft(President, Chief Executive Officer and Director)John Bencich(Chief Financial Officer)inChad Oh(Chief Medical Officer)inAlex Wilson(Chief Legal & Strategy Officer; Corporate Secretary)inJennifer Sy(Chief Accounting Officer)in

BioAge Labsbioagelabs.comin𝕏NASDAQ: BIOAFeb 2024

BIOAGE develops therapies targeting the molecular pathways that drive aging to increase healthspan and address age-related chronic diseases.

BiotechHealthtechLongevityRichmond, US

Kristen Fortney, PhD(Co-Founder, CEO)Eric Morgen, MD(Co-Founder, COO)Kristen Fortney(Executive Officer, Director)inEric Morgen(Director)inDov Goldstein(Executive Officer)in

BoardPatrick Enright(Director)in

Co-investorsAndreessen HorowitzElad GilFelicis VenturesIA Seed VenturesOrbiMedPear VC+5 more

Boston Scientificbostonscientific.cominNYSE: BSXAcquired

Boston Scientific supports external researcher-initiated studies through its Investigator Sponsored Research program, which funds independent investigations addressing disease understanding and treatment gaps of interest to the medical community.

HealthtechMedical Devices

John AbeleinPeter NicholasLance BatesinJonathan R. Monson(Executive Vice President and Chief Financial Officer)Miriam O'Sullivan(Senior Vice President, Chief Human Resources Officer)inMichael F. Mahoney(Chairman of the Board, President and Chief Executive Officer)

Co-investorsAndera PartnersCatalyst Health VenturesCouncilExcelestar VenturesGood Growth CapitalNew Enterprise Associates (NEA)+6 more

CG Oncologycgoncology.comin𝕏NASDAQ: CGON

CG Oncology develops an investigational oncolytic immunotherapy for urologic cancer patients, specifically targeting BCG-unresponsive non-muscle invasive bladder cancer.

BiotechHealthtechMedical Devices

Arthur Kuan(Chairman and Chief Executive Officer)in

Co-investorsDecheng CapitalForesite CapitalPalm Drive CapitalRA CapitalTCG CrossoverACORN BIOVENTURES+2 more

Collegium Pharmaceuticalcollegiumpharma.comin𝕏NASDAQ: COLL

Collegium Pharmaceutical is a biopharmaceutical company developing a portfolio of medications to treat serious medical conditions.

BiotechCanton, US

Michael Heffernan(Executive Officer, Director)inPaul Brannelly(Executive Officer)inVikram Karnani(President and Chief Executive Officer, and Director)in

BoardEran Nadav(Director)John Freund(Director)Patrick Heron(Director)in

Co-investorsAPERTURE Venture PartnersEcoR1 CapitalFrazier Life SciencesBoston Millennia PartnersRA Capital

Corcept Therapeuticscorcept.cominNASDAQ: CORT

Corcept develops cortisol modulators — molecules that regulate cortisol activity at the glucocorticoid receptor — to treat serious diseases across endocrinology, oncology, metabolism, and neurology.

AI & Machine LearningBiotechHealthtechMedical Devices

Joseph K. Belanoff(Chief Executive Officer and President)

Co-investorsMountain Group Capital

CytomXcytomx.comin𝕏NASDAQ: CTMX

CytomX is a clinical-stage biopharmaceutical company developing conditionally activated biologic cancer therapies, including antibody-based treatments designed to target tumors while limiting effects on healthy tissue.

BiotechHealthtechSouth San Francisco, US

Sean McCarthy(Executive Officer, Director)inSean A. McCarthy(Chief Executive Officer and Chairman)inMarcia P. Belvin(SVP, Chief Scientific Officer)inDawn Benson(SVP, Quality and Product Manufacturing)inWayne Chu(Chief Medical Officer)Rachael Lester(SVP, Chief Business Officer)in

Co-investorsCanaan PartnersPfizer Venture InvestmentsOrbiMedThird Rock Ventures

KALA BIOkalarx.cominNASDAQ: KALA

A biopharmaceutical company developing an artificial intelligence infrastructure platform designed for on-premises deployment in biotechnology and pharmaceutical research environments, serving biotech firms and pharma companies seeking secure access to advanced AI capabilities while retaining control over proprietary biological data; the company is also evaluating strategic alternatives for its legacy mesenchymal stem cell secretome assets after discontinuing its lead rare eye disease therapeutic program.

BiotechArlington, US

Justin Hanes(Director)inKevin Pojasek(Executive Officer)inDarius Kharabi(Executive Officer)inTodd Bazemore(Executive Officer)inMark Iwicki(Executive Officer, Director)inMary Reumuth(Executive Officer)in

Co-investorsSR One Capital ManagementYsios CapitalAtlas VentureLux CapitalRA CapitalThird Rock Ventures

Kestra Medical Technologieskestramedical.cominNASDAQ: KMTSJul 2024 · $200M

Kestra Medical Technologies develops wearable medical devices and digital healthcare solutions designed for collaborative care between providers and patients.

Digital HealthHardwareHealthtechMedical Devices

Brian Webster(President, Chief Executive Officer, and Director)inTraci S. Umberger(General Counsel, Chief Administrative Officer, and Director)inVaseem Mahboob(Chief Financial Officer)inAl Ford(Chief Commercial Officer)inTimothy Moran(Chief Business Officer)

Co-investorsAndera PartnersBain Capital Life SciencesBain CapitalBain Capital Venture

MicroTranspondermicrotransponder.comin𝕏NASDAQ: MOBI

Mobia Medical (formerly MicroTransponder) develops Vivistim Paired VNS Therapy, an FDA-approved treatment for stroke survivors with moderate to severe upper extremity impairment.

Digital HealthHealthtechMedical DevicesAustin, US

Richard John Foust(Executive Officer, Director)Frank McEachern(Executive Officer, Director)in

BoardNelson Bunker Curnes(Executive Officer, Director)Thomas Jordan Curnes II(Executive Officer, Director)Casey Tansey(Director)Dana Mead(Director)

Co-investorsUT Horizon FundGreen Park & Golf VenturesUS Venture Partners

Rxsightrxsight.comin𝕏NASDAQ: RXSTJun 2015 · $52M

RxSight develops the Light Adjustable Lens (LAL), an FDA-approved intraocular lens that surgeons can adjust after cataract surgery to fine-tune a patient's prescription once the eye has healed.

HealthtechMedical DevicesPasadena, US

Robert H. Grubbs(Director)Daniel M. Schwartz(Director)D. Verne Sharma(Executive Officer, Director)Richard Drinkward(Executive Officer)inRon Kurtz(President, Chief Executive Officer & Director)Mark Wilterding(Chief Financial Officer)in

Co-investorsFlying L PartnersForesite CapitalH.I.G. CapitalH.I.G. HealthBridge PartnersRA CapitalVisionary Ventures+2 more

SutroVaxNASDAQ: PCVX

BiotechSouth San Francisco, US

Grant E. Pickering(Chief Executive Officer)Ashish Khanna(Executive Officer)Jeff Fairman(Executive Officer)

BoardTracy Saxton(Director)William Newell(Director)Kurt von Emster(Director)in

Co-investorsAbingworthCTI Life Sciences Fund L.P.Foresite CapitalFrazier Life SciencesJanus Henderson InvestorsMedicxi+4 more

Vaxcytevaxcyte.comNASDAQ: PCVX

Vaxcyte develops broad-spectrum vaccines to prevent bacterial infections, using a cell-free protein synthesis platform and synthetic chemistry techniques.

BiotechHealthtech

Grant Pickering(Founder)inGrant E. Pickering(Chief Executive Officer and Director)in

Co-investorsBioRock VenturesCTI Life Sciences Fund L.P.Foresite CapitalFrazier Life SciencesRA CapitalJanus Henderson Investors+2 more

Veratxveratx.comin𝕏NASDAQ: VERAOct 2020

Vera Therapeutics develops medicines targeting autoimmune-driven kidney diseases, with a focus on reducing the need for dialysis or transplant.

BiotechDigital HealthMedical DevicesSouth San Francisco, US

Marshall Fordyce(Executive Officer, Director)in

BoardBeth Seidenberg(Director)inMaha Katabi(Director)inKurt von Emster(Director)inPatrick Enright(Director)inAndrew Cheng(Director)

Co-investorsKleiner PerkinsSofinnova VenturesAbingworthSofinnova Venture Partners

Zenas Biopharmazenasbio.cominNASDAQ: ZBIO

Zenas BioPharma is a biopharmaceutical company developing therapies for autoimmune diseases, with two late-stage drug candidates: obexelimab, a bifunctional monoclonal antibody targeting CD19 and FcγRIIb to suppress B cell activity, and orelabrutinib, an oral BTK inhibitor.

BiotechHealthtechWaltham, US

LEON O. MOULDER, JR.(Director)Lonnie Moulder(Founder, CEO & Chairman)JOSEPH FARMER(Executive Officer)HUA MU(Executive Officer, Director)in

BoardPATRICK GERALD ENRIGHT(Director)inHONGBO LU(Director)

Co-investorsDelos CapitalNew Enterprise Associates (NEA)Norwest Venture PartnersQuan CapitalSR One Capital ManagementVivo Capital+1 more

Alentisalentis.chin✓ verified

Alentis is a biotech company developing therapies for chronic liver disease, fibrosis, and cancer based on the molecular biology of liver disease.

AI & Machine LearningBiotechHealthtechMedical DevicesBasel, CH

Thomas Baumert(Founder)inMark Pruzanski(Chief Executive Officer)inLuigi Manenti(Chief Medical Officer)inJon Freve(Chief Financial Officer)inBryan Yoon(General Counsel and Chief Administrative Officer)inAditya Venugopal(Chief Business Officer)in

Co-investorsAvego BioScience CapitalBioMedPartnersFrazier Life SciencesJeito CapitalNovo HoldingsOrbiMed+5 more

Avicedarxavicedarx.comin𝕏✓ verified

Aviceda is a company that presents itself as backed by a range of investors, but the page provides no concrete details about its products or business area.

BiotechDigital HealthHealthtechMedical Devices

Mohamed A. Genead(Chairman & CEO)inJeffrey Nau(Chief Executive Officer)inTarek S. Hassan(Chief Development Officer)in

Co-investorsJeito CapitalOrbiMedDigitalis Ventures

Curasencurasen.com✓ verified

CuraSen Therapeutics is a privately funded biopharmaceutical company developing treatments that selectively activate adrenergic receptors in the brain to restore noradrenergic signaling.

BiotechHealthtech

Anthony Fordin

Co-investorsAlta Partnersabrdn plcIntermediate Capital GroupJohnson & Johnson Innovation – JJDCNew Leaf Venture PartnersPappas Capital+2 more

OrsoBioorsobio.comin𝕏Nov 2023 · $60M✓ verified

OrsoBio develops therapies to restore energy homeostasis in patients with severe metabolic disorders, drawing on biological research including human liver organoids and insights from metabolic pathways.

BiotechDeep TechMedical DevicesMenlo Park, US

Mani Subramanian(Executive Officer, Director)inGangadhara Ganapati(Executive Officer, Director)Dr. SubramanianDr. Myers

BoardMatthew Young(Director)inSrinivas Akkaraju(Director)

Co-investorsAscenta CapitalSamsara BioCapitalF-Prime Capital

Sydnexissydnexis.comin✓ verified

Sydnexis is a privately held biopharmaceutical company developing SYD-101, a proprietary low-dose atropine formulation in Phase 3 clinical trials to slow the progression of pediatric progressive myopia.

BiotechDigital HealthDel Mar, US

Patrick Johnson(Executive Officer, Promoter)inMary Jaqueline Johnson(Executive Officer)Mary Jacqueline Johnson(Executive Officer)Kevin Johnson(Director)Greg Ostrow(Executive Officer, Director)Kenneth Widder(Executive Officer, Director)

Co-investorsRA CapitalVisionary Ventures

Venus Conceptvenusconcept.comin𝕏Nov 2019 · $10M

Venus develops non-invasive, energy-based medical aesthetic devices for body, face, skin, and hair treatments, integrating robotics, AI, and IoT technologies.

BiotechHardwareHealthtechMedical DevicesToronto, US

Domenic Serafino(Executive Officer, Director)inKirk Gunhus(Executive Officer)inRoss Portaro(Executive Officer)inAnna Georgiadis(Executive Officer)inMelissa Kang(Executive Officer)inMichael Mandarello(Executive Officer)in

Board seatJuliet Bakker· per SEC Form D

Co-investorsAPERTURE Venture PartnersEssex Woodlands Healthcare PartnersClarusHealthQuest Capital

89bio (NASDAQ: ETNB)89bio.comin

A clinical-stage biopharmaceutical company developing investigational therapies for patients with liver and cardiometabolic diseases, with a lead candidate (pegozafermin) being evaluated for metabolic dysfunction-associated steatohepatitis and severe hypertriglyceridemia.

BiotechHealthtechMedical DevicesSan Francisco, US

Rohan Palekar(Founder)in

Co-investorsK2 HealthVentures

Akebia Therapeuticsakebia.comin𝕏

Akebia Therapeutics develops FDA-approved drug therapies for the treatment of kidney disease.

BiotechHealthtechMedical DevicesCambridge, US

John P. Butler(President and Chief Executive Officer)in

Co-investorsCincyTech

Alpha-9 Oncologya9oncology.cominOct 2024

Alpha-9 Oncology develops radiopharmaceuticals for cancer treatment, with a portfolio of molecules in clinical and preclinical development.

BiotechDigital HealthMedical DevicesVancouver, CA

François Bénard(MD)Kuo-Shyan Lin(PhD)David Perrin(PhD)

Co-investorsAndreessen HorowitzAscenta CapitalDelos CapitalGeneral CatalystLightspeed Venture PartnersLumira Ventures+9 more

Amarinamarincorp.comin𝕏

Amarin Corporation is a cardiovascular health pharmaceutical company developing treatments to prevent cardiovascular disease.

BiotechHealthtechMedical Devices

Co-investorsAvoro Capital AdvisorsFountain Healthcare PartnersSignet Healthcare PartnersSofinnova Ventures

Amphoraamphoralogistics.comin

Amphora provides logistics services aimed at supporting business growth and operational efficiency.

E-commerceLogistics & Supply ChainSaaS

Joan Tresserras(Founder)inAdrià Cortés(Founder)in

Co-investorsBStartupBaird CapitalF-Prime CapitalHBM Healthcare Investments

Aptinyxaptinyx.com

BiotechEvanston, US

Joseph R. Moskal(Chief Scientific Officer)Torsten M. Madsen(Chief Marketing Officer)Ashish Khanna(Secretary & Chief Business Officer)Norbert G. Riedel(Chief Executive Officer)

BoardLiam Ratcliffe(Director)Terry P. Gould(Director)

Co-investorsBain Capital Life SciencesFrazier Life SciencesLatterell Venture PartnersOUP (Osage University Partners)Agent CapitalHBM Healthcare Investments+2 more

Aptus Endosystemsin𝕏acquired by Medtronic · Jun 2015 · $110M

Aptus Endosystems developed endovascular devices, including the Heli-FX EndoAnchor systems, that use helical anchors to secure stent-grafts during minimally invasive aortic aneurysm repair.

HealthtechMedia & EntertainmentMedical Devices

Co-investorsUS Venture Partners

Assemblybioassemblybio.comin

Assembly Bio is a biopharmaceutical company developing novel therapeutic candidates for viral and liver diseases, including programs targeting herpesviruses, hepatitis delta virus, hepatitis B virus, and cholestatic liver diseases.

BiotechHealthtechMedical Devices

Jason Okazaki(Chief Executive Officer & President)inWilliam Delaney, PhD(Chief Scientific Officer)Anuj Gaggar, MD, PhD(Chief Medical Officer)

Co-investorsAvoro Capital Advisors

Aviceda Therapeuticsin

BiotechCambridge, US

Mohamed Genead(Executive Officer, Director)inMichael Tolentino(Executive Officer, Director)inDavid Callanan(Executive Officer)inTarek Hassan(Executive Officer)inDerek Kunimoto(Executive Officer)in

BoardDavid Guyer(Director)

Co-investorsCatalio Capital Management, LPJeito CapitalAvoro Capital AdvisorsOmega Funds

Axonicsaxonics.comin

Boston Scientific develops medical devices and technologies used by healthcare professionals to treat patients across a range of conditions.

HealthtechMedical Devices

Raymond Cohenin

Co-investorsAdvent Life SciencesAndera Partners

Baronovabaronova.comin

Non-surgical, non-pharmacologic devices to induce weight loss

Co-investorsDelos CapitalArboretum VenturesHighland Capital PartnersSante Ventures

Bina health-beautyin𝕏

BiotechHealthtechMedical Devices

Co-investorsSGH CapitalSunstone Capital

Boltmedboltmed.comin

Bolt Medical develops the Bolt IVL intravascular lithotripsy system, a laser-based balloon catheter platform that fractures arterial calcium using acoustic pressure waves to treat coronary and peripheral artery disease.

HardwareHealthtechMedical DevicesMarlborough, US

Campfieldtxcampfieldtx.comin

cAMPfield is a clinical-stage biopharmaceutical company developing prifemilast, a once-daily oral PDE4B-selective inhibitor for immune-mediated inflammatory diseases, primarily inflammatory bowel disease (ulcerative colitis and Crohn's disease).

BiotechHealthtech

Graham Heap(President, Research and Development)inEzequiel Neimark(Head of Clinical Development)inTaylor Spector(Head of Medical Affairs)inScott Stirn(Head of CMC)in

Co-investorsFrazier Life Sciences

Civitas Therapeuticscivitastherapeutics.comAug 2014

BiotechChelsea, US

RICHARD BATYCKY(Executive Officer)GLENN BATCHELDER(Director)BRYAN STUART(Executive Officer)inMARK IWICKI(Executive Officer, Director)inMARTIN FREED(Executive Officer)in

BoardROB HOPFNER(Director)in

Co-investorsCanaan PartnersSofinnova VenturesBay City CapitalOrbiMedRA Capital

Cohere Healthcoherehealth.cominFeb 2024 · $50M

Cohere Health provides a platform aimed at aligning the interests of patients, physicians, and health plans to support care decisions and improve member outcomes.

AI & Machine LearningDigital HealthEnterprise SoftwareHealthtechSaaSBoston, US

Siva Namasivayam(Executive Officer, Director)inRobert Shepardson(Executive Officer)inKristen Carucci(Executive Officer)inDuncan Reese(Executive Officer)

BoardDavid Barrett(Director)Amir Debourou(Director)

Co-investorsCota CapitalFlare Capital PartnersDeerfield Management CompanyDefine VenturesFlare Capital StrategiesPolaris Partners+1 more

Corticacorticacare.comin

Cortica provides in-home, in-clinic, and telehealth neurological therapies for children with autism and developmental differences, integrating neurological, biomedical, behavioral, speech-language, and sensorimotor treatments.

Digital HealthHealthtechMedical DevicesSan Diego, US

Dr. Suzanne Goh(Founder)Neil Hattangadi(Executive Officer, Director)inBriana Elvaiah(Executive Officer)in

BoardRyan Drant(Director)inStephen Anastos(Director)Justin Brock(Director)in

Co-investors.406 VenturesAIFAPERTURE Venture PartnersCVS Health VenturesEcho Health VenturesOptum Ventures+5 more

Crownwheelpartnerscrownwheelpartners.com

JAN46 is an online gaming platform offering game top-ups (in-game credits/items) with automated delivery, along with esports tournaments featuring live brackets and streaming, and player community tools.

ConsumerGaming

CV Therapeuticsgilead.comin𝕏

Gilead discovers, develops, and delivers innovative therapeutics for people with life-threatening diseases, focusing on virology, oncology, and inflammation across more than 35 countries.

BiotechDigital HealthHealthtechMedical DevicesFoster City, US

Lou Lange(Founder)Michael L. Riordan(Founder)inDaniel O'Dayin

Co-investorsAisling CapitalAsset Management CompanyFrazier Life SciencesKleiner PerkinsLumira VenturesMenlo Ventures+5 more

Eargoeargo.comDec 2018 · $82MDefunct

Eargo was a hearing aid company that provided high-quality hearing aids and related care services.

HealthtechMedical DevicesMountain View, US

Raphael Michel(Executive Officer, Director)Christian Gormsen(Executive Officer, Director)William Brownie(Executive Officer)Peter Tuxen Bisgaard(Director)

BoardDavid Wu(Director)inJosh Makower(Director)

Co-investorsBirchmere VenturesMaveronNew Enterprise Associates (NEA)Dolby Family VenturesMontage VenturesPatient Square Capital+1 more

Endeavor Biomedicinesendeavorbiomedicines.comin𝕏

Endeavor BioMedicines is a biopharmaceutical company developing medicines aimed at treating patients with serious, intractable diseases, with the goal of altering disease progression rather than only slowing it.

BiotechSan Diego, US

John Hood(Co-Founder, Chief Executive Officer & Executive Chairman)inWing Cheong Lam(Director)Bernard Davitian(Director)Raghu Saripalli(Executive Officer)Monal Mehta(Director)inMiguel de los Rios(Co-Founder & Chief Scientific Officer)in

Co-investorsFidelity InvestmentsOmega Funds

Endogenexendogenex.comin𝕏Series C · Jun 2024 · $88M

Endogenex is a clinical-stage medical device company developing the pulsENDO system, which applies non-thermal pulsed electric field to reset the body's metabolic signaling and improve function in people with type 2 diabetes.

Digital HealthHealthtechMedical DevicesMinneapolis, US

Stacey Pugh(Leadership (CEO))inChris Sorli, MD, PhD(Chief Medical Officer)inKrissy Wright(Chief Financial Officer)inLian Cunningham, MD, PhD(VP Clinical Affairs)inMelanie Hess(Regulatory Affairs Leadership)inMatt Cambronne(Technical/Engineering Leadership)in

Co-investorsArboretum VenturesIntuitive VenturesLumira Ventures

Epiriumepirium.comDec 2019 · $85M

Epirium Bio develops novel oral therapeutics targeting mitochondrial dysfunction and muscle diseases, particularly muscular dystrophy.

BiotechMedical DevicesSan Diego, US

Pam Taub(M.D., FACC, Founder)Alan Maisel(M.D., Founder)Francisco Villarreal(M.D., Ph.D., Founder)Jonathan Taub(Co-founder and first Chief Executive Officer)Guillermo Ceballos(M.D., Founding Scientist)Pam Taub, M.D., FACC(Co-founder)

Co-investorsBluebird VenturesBroadview VenturesAdams Street PartnersARCH Venture PartnersVertex VenturesVertex Ventures HC

Esperion Therapeuticsesperion.comJun 2014

BiotechAnn Arbor, US

Antonio M. Gotto, Jr.(Director)Tim M. Mayleben(Executive Officer, Director)Gilbert S. Omenn(Director)Daniel Janney(Director)Dov A. Goldstein(Director)Roger S. Newton(Director)

Co-investorsAisling CapitalAlta PartnersArboretum VenturesARCHIMED JapanAsset Management CompanyCanaan Partners+2 more

FIRE1fire1foundry.comin𝕏Jan 2025 · $120M

FIRE1 develops NORM, an implantable sensor placed in the inferior vena cava to directly measure fluid volume in heart failure patients, paired with a self-management platform to help patients engage with their own care.

Digital HealthHardwareMedical DevicesDublin, IE

Co-investorsAndera PartnersLightstone VenturesNew Enterprise Associates (NEA)Gilde HealthcareGimvIreland Strategic Investment Fund+5 more

Generategenerate.comin

Generate Life Sciences was a reproductive, newborn stem cell, and genetic services company offering products and services to help families grow and protect their families.

BiotechDigital HealthHealthtech

Helicorehelicore.comJan 2025

Helicore Bio develops long-acting antibody-peptide conjugate therapies for obesity and cardiometabolic disease, using proprietary GLP-1R agonist and amylin receptor agonist peptide libraries combined with a GIP ligand-binding antibody backbone.

BiotechHealthtechSouthbury, US

Kevin Russ(Chief Executive Officer)inWaters Kellogg(Director)Lucas B. Turner(Director)Joshua Dotson(Director)Holger Koehler(Director)Charles Bridge(Director)

Co-investorsOrbiMedVersant VenturesWellington Management

Helomicshelomics.cominMay 2017acquired by Predictive Oncology

Predictive Oncology (POAI) operates an AI/ML platform powered by a biobank of over 150,000 tumor samples across 137 cancer types to predict tumor-drug response for oncology drug discovery.

AI & Machine LearningBiotechHealthtechPittsburgh, US

GERALD J. VARDZEL JR.(Executive Officer, Director)DOUGLAS ARMSTRONG(Executive Officer, Director)

BoardROBERT D. KEYSER JR.(Director)RICHARD AULICINO(Director)

Infinant Healthinfinanthealth.comin𝕏May 2026

Infinant Health develops probiotic products based on B. infantis strains that work with breast milk to support the infant gut microbiome, including its INF108 drug strain aimed at preventing necrotizing enterocolitis (NEC) in premature infants.

BiotechDigital HealthFemTechHealthtechWellness & FitnessSacramento, US

J. Bruce German(Co-founder)David Mills(Co-founder)inCarlito Lebrilla(Co-founder)Daniela Barile(Co-founder)Samara Freeman(Co-founder & Director of Intellectual Property and Regulatory Affairs)inMichael Johnson(Executive Officer, Director)

Co-investorsAcre Venture PartnersBow CapitalHorizons VenturesiSelect FundBill & Melinda Gates FoundationSpruce Capital Partners

Inozyme Pharmainozyme.com

BiotechBoston, US

Axel Bolte(Executive Officer, Director)inReinaldo Diaz(Director)Joseph Schlessinger(Executive Officer, Director)

BoardEdward Mathers(Director)Rob Hopfner(Director)inMartin Edwards(Director)

Co-investorsNew Enterprise Associates (NEA)Sanofi VenturesSofinnova VenturesPivotal Life Sciences

Intelycareintelycare.comin𝕏Apr 2022 · $115M

IntelyCare operates a healthcare talent marketplace that connects nurses with care settings including hospitals, clinics, and other healthcare facilities.

B2B MarketplacesFuture of WorkHealthtechHR TechQuincy, US

Ike Nnah(Executive Officer, Director)inDavid Coppins(Executive Officer, Director)inPrince Nnah(Director)

Co-investorsEastward Capital PartnersEndeavour VisionEquitage Ventures, L.L.C.Generator VenturesKaiser Permanente VenturesTRANSFORMATION CAPITAL+3 more

Jazz Pharmaceuticaljazzpharma.comin𝕏

Jazz Pharmaceuticals is a biopharmaceutical company developing treatments for rare diseases and cancers, with a focus on oncology and biomarker-driven therapies such as those targeting HER2-expressing cancers.

BiotechHealthtech

Co-investorsProspect Venture PartnersRex Health VenturesSolas BioVentures

Lassen Therapeuticslassentherapeutics.cominJan 2024 · $85M

Lassen Therapeutics is a biotechnology company developing therapeutics targeting IL-11, with a pipeline focused on immune and fibrotic diseases.

Biotech

David King(Co-Founder & CSO)inMaria Fardis(CEO)inCadmus C. Rich(Chief Medical Officer)inElaine Stracker(General Counsel)in

Co-investorsAlta PartnersCatalio Capital Management, LPDC Investment PartnersLongwood FundBiotechnology Value FundCatalio Capital Management+2 more

Lexeotxlexeotx.comin

Lexeo is a clinical-stage genetic medicine company developing gene therapies that target the genetic causes of cardiovascular diseases.

BiotechDigital HealthHealthtechNew York City, US

Ronald Crystal, MD(Founder & Chief Scientific Adviser)R. Nolan Townsend(Chief Executive Officer)inNarinder Bhalla, MD(Chief Medical Officer)José Manuel Otero, PhD(Chief Operating Officer)Louis Tamayo(Chief Financial Officer)in

Co-investorsOrbiMed

Limflowlimflow.comApr 2022 · $39M

LimFlow develops a medical device system for the treatment of chronic limb-threatening ischemia.

HealthtechMedical Devices

Co-investorsSofinnova Partners

Locus Bioscienceslocus-bio.comin𝕏Feb 2024 · $152M

Locus Biosciences develops engineered bacteriophage therapies for treating bacterial infections and conditions in immunology, oncology, and CNS disorders.

AI & Machine LearningBiotechDeep TechHealthtechRaleigh, US

Paul Garofolo(CEO & Co-founder)NICK TAYLOR(Executive Officer)inNick Conley(Vice President of Technology (Co-founder of EpiBiome, acquired by Locus))in

BoardGEOFFREY GLASS(Director)inDAVID JOHNSTON(Director)BARY BAILEY(Director)

Co-investorsArtis VenturesAbstract VenturesHemisphere Ventures LLCDomain AssociatesStarlight Ventures

Lumena Pharmaceuticalsin𝕏acquired by Shire

Acquired by Shire in 2014 (now part of Takeda).

BiotechMedical Devices

Co-investorsFrazier Life SciencesOberland CapitalRiverVest Venture Partners

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

AlphaeonAxonics Modulation TechnologiesAimmuneAirNexisAllergen ResearchAmphora MedicalAmunixAqueSysAvengebioCheckmate PharmaceuticalsCheckmatepharmaCydan IIDascenaGcs WebInflazomeNabrivaNeurana PharmaceuticalsOpna BioRapidmicrobioTalaris TherapeuticsTalaristxTourmaline BioVelicept Therapeutics

Exits · 26

17 IPOs · 9 acquisitions · showing 25

VeradermicsNYSE: MANECeribellNASDAQ: CBLLAeonbiopharmaNYSE: AEONBioAge LabsNASDAQ: BIOABoston ScientificNYSE: BSXCG OncologyNASDAQ: CGONCollegium PharmaceuticalNASDAQ: COLLCorcept TherapeuticsNASDAQ: CORTCytomXNASDAQ: CTMXKALA BIONASDAQ: KALAKestra Medical TechnologiesNASDAQ: KMTSMicroTransponderNASDAQ: MOBIRxsightNASDAQ: RXSTSutroVaxNASDAQ: PCVXVaxcyteNASDAQ: PCVXVeratxNASDAQ: VERAZenas BiopharmaNASDAQ: ZBIOAmphora Medicalacq. by HologicAptus Endosystemsacq. by MedtronicCheckmate Pharmaceuticalsacq. by Regeneron PharmaceuticalsHelomicsacq. by Predictive OncologyLumena Pharmaceuticalsacq. by ShireNxStage Medicalacq. by Fresenius Medical CarePentec Health Celebrates 35th Anniversaryacq. by Wellspring Capital ManagementThumbnail for Constellation Pharmaceuticalsacq. by Morphosys

Portfolio news

latest coverage across their companies

Fund performance · per public LP disclosures

as of Jun 2025
FundVintageCommittedNet IRRTVPIDPI
Longitude Venture Partners IIILPs: Los Angeles City Employees' Retirement System, Maryland State Retirement and Pension System201616.8%1.68x0.96x

Source: public limited-partner disclosures (CalPERS, CalSTRS). Net IRR / TVPI / DPI as reported by the limited partner; a fund's early-year IRR is an interim estimate (J-curve).

IPO stake values · per SEC filings · 7

Value of this firm's stake in each portfolio company at its IPO price, from the prospectus principal-stockholder table.

CompanyOwnedIPO priceAt IPOStake value
Veradermics11.3%$100.00Apr 2026$465.4M
CG Oncology6.2%$28.00Dec 2024$130.5M
Veratx11.9%$15.00Feb 2022$46.4M
Ceribell7.3%$17.00Oct 2024$42.1M
Zenas Biopharma5.2%$17.00Sep 2024$35.1M
KALA BIO8.8%$15.00Jul 2017$30.8M
BioAge Labs3.8%$18.00Sep 2024$23.6M

Source: SEC S-1 / 424B prospectus filings. Stake value = shares beneficially owned × the initial public offering price, as disclosed — a market value at IPO, not a return multiple (the firm's original cost is not disclosed).

Public market activity · per SEC filings

what is this? ⓘ

2 insider ownership filings (Forms 3/4/5)

at Veradermics, Inc (MANE)

From the firm's own SEC EDGAR filings — stakes and insider roles in public companies, typically portfolio companies after an IPO. Not a portfolio list published by the firm.

Frequently asked questions

How many investments has Longitude Capital made?
Longitude Capital has 107 tracked investments, 26 of which have exited, including 5 dated in the last 24 months.
What stage does Longitude Capital invest at?
Longitude Capital invests at the Series A, Series B, Series C, Growth, Late Stage stages.
What is Longitude Capital's typical check size?
Longitude Capital typically writes checks of $10M – $30M.
What sectors does Longitude Capital focus on?
Longitude Capital focuses on Biotech, Digital Health, Healthtech, Longevity, Medical Devices.
Where is Longitude Capital located?
Longitude Capital is headquartered in Menlo Park, US.
Does Longitude Capital lead rounds?
Yes, Longitude Capital leads investment rounds.
Who does Longitude Capital co-invest with?
Longitude Capital most often shares deals with RA Capital, Frazier Life Sciences, New Enterprise Associates (NEA), among 162 tracked co-investors.

Co-investors · 6

Pivotal Life Sciences

Pivotal Life Sciences is an investment platform focused on funding innovative companies developing therapeutic products and technologies aimed at major unmet medical needs.

Menlo Ventures

Menlo Ventures is a venture capital firm that invests in transformative, early-stage AI companies across every layer of the modern AI stack, from applications and middleware to data infrastructure and foundation models.

Both backed · 2
$1M – $20M
Vensana Capital

Vensana Capital is a venture capital and growth equity investment firm focused on partnering with entrepreneurs building breakthrough medical technology innovations to transform healthcare.

Bain Capital Venture

Bain Capital is a global private investment firm operating across private equity, growth and venture capital, credit, capital solutions, and real assets, with offices in North America, Europe, and Asia-Pacific. The firm invests across industries and business life cycles, from seed-stage venture investments through buyouts, and integrates sustainability commitments into its portfolio governance.

Longwood Fund

Longwood Fund is a venture capital firm that creates and invests in novel healthcare companies developing new treatments for patients, drawing on its partners' company-building and operating experience.

Both backed · 1

Firms observed investing alongside Longitude Capital, from public investor directories. Shared companies are the overlap with Longitude Capital's recorded portfolio.

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