SV Health Investors
Venture capitalBoston · Pre-Seed–Late Stage · 26 people tracked
Also known as SV HEALTH INVESTORS, LLC · SV HEALTH MANAGERS LLP
Investment thesis
SV Health Investors backs diverse entrepreneurs building breakthrough healthcare companies and treatments, aiming to transform healthcare one investment at a time. The firm operates a global private equity and venture capital platform with specialized and diversified healthcare funds spanning all sectors and stages. It runs three dedicated teams focused on biotechnology (including dementia), healthcare growth equity, and medtech. With one of the longest track records among healthcare investment managers, the firm pairs experienced investment professionals with healthcare industry veterans to add value and guide strategic direction, helping portfolio companies attract strategic acquirers and public investors while benefiting patients and growing shareholder value.
Source: firm website, verified Aug 11, 2026.
Team · 26 people
from the firm's website & public directoriesWhat they invest in
from 41 of 206 portfolio companiesHealthtech ×30Biotech ×22Medical Devices ×17Deep Tech ×5Digital Health ×5AI & Machine Learning ×4Data & Infrastructure ×1Enterprise Software ×1
HQs:United States×37Canada×1Ireland×1
Investments · 206 tracked
founders shown can be your intro pathBy year:2026 · 22025 · 22024 · 22020 · 12019 · 12018 · 22017 · 12016 · 52015 · 12014 · 118 dated
Bedford, US
Board seatCharles Warden· per SEC Form D
Alector develops therapies targeting neurodegenerative diseases including Alzheimer's, frontotemporal dementia, and Parkinson's disease through protein removal, replacement, and immune cell restoration.
AI & Machine LearningBiotechHealthtechLongevityMedical DevicesSan Francisco, US
Arnon Rosenthal(Ph.D.)Carl Gordon(Director)Tillman Gerngross(Director)
BoardTerry McGuire(Director)
Enabling telemedicine and digital health
Biotech company that reached IPO
BiotechCambridge
KEVIN LEE(Executive Officer, Director)FELIX J. BAKER(Director)RICHARD N. KENDER(Director)GREGORY WINTER(Director)STEPHEN SANDS(Director)NIGEL CROCKETT(Executive Officer)
Xilio (Xilio Therapeutics) is a clinical-stage biotechnology company developing tumor-selective immunotherapies, including checkpoint inhibitors, T cell engagers and related molecules, for the treatment of cancer.
BiotechHealthtechWaltham, US
Paul Clancy(Director)Daniel Curran(Director)Nancy Hong(Director)Rachel Humphrey(Director)Daniel Lynch(Director)Michael Ross(Director)
Alchemab operates a platform that identifies novel drug targets and therapeutics by analyzing patient antibody repertoires using deep B cell sequencing and computational analysis of samples from disease-resilient individuals.
AI & Machine LearningBiotechDeep TechHealthtech
Jane Osbourn(Chief Executive Officer)
EBT Medical develops neuromodulation technologies targeting the Saphenous nerve to treat pelvic health disorders, particularly overactive bladder.
BiotechMedical Devices
Paul Yoo(Co-founder, President & Chief Scientific Officer)Sasha John(Co-founder and Chief Innovation Officer)Keith R Carlton(Chief Executive Officer)
Mestag Therapeutics is an immunology company developing first-in-class agonist antibody therapies for cancer and inflammatory diseases based on fibroblast biology, and operates a RAFT platform for discovering new drug targets.
AI & Machine LearningBiotechHealthtech
Susan Hill(Founder & Chief Executive Officer)Michael B. Brenner(Founder)Chris Buckley(Founder)Mark Coles(Founder)Soumya Raychaudhuri(Founder)David A. Tuveson(Founder)
Axon Therapies develops the SAVM procedure, an implant-free catheter-based ablation therapy that targets the right greater splanchnic nerve to reduce overactive sympathetic nerve activity in patients with heart failure with preserved ejection fraction (HFpEF).
HealthtechMedical DevicesNew York, US
Howard R. Levin(Executive Officer, Director)Mark Gelfand(Executive Officer)Mitchell S. Bloom(Executive Officer)
Board seatPaul LaViolette· per SEC Form D · $2M raise · filed Apr 2016
Marlborough, US
Bruce Robertson(Director)Lauren Jennings(Executive Officer)Christopher Kroeger(Director)Omar Amirana(Director)Warren Clark(Executive Officer)James Garvey(Director)
Board seatPaul LaViolette· per SEC Form D
BiotechTewksbury, US
George J. Fazio(Executive Officer, Director)Dan B. Curtis(Executive Officer)David S. Celermajer(Director)Uri Geiger(Director)Hemant Taneja(Director)
Board seatPaul LaViolette· per SEC Form D · $11.1M raise · filed Jun 2025
RejuvenAir, developed by CSA Medical, is a bronchoscopic cryosurgical device that sprays metered doses of liquid nitrogen to destroy damaged airway cells and treat the underlying cause of COPD with Chronic Bronchitis.
HealthtechMedical DevicesLutherville, US
Vincent Owens(Director)Ellen Sheets(Executive Officer, Director)Richard Kent(Director)Thomas Snead(Director)Ian J. Vawter(Executive Officer)
BoardTracy Marshbanks(Director)
Board seatPaul LaViolette· per SEC Form D
HealthtechSanta Rosa, US
Yuval Binur(Director)Dan Rose(Executive Officer)Gordon Bishop(Executive Officer, Director)George Fazio(Director)David Boyle(Executive Officer)Dan T. Lemaitre(Executive Officer, Director)
Board seatPaul LaViolette· per SEC Form D
Endotronix develops the Cordella PA Sensor and Heart Failure System, an FDA-approved implantable pulmonary artery sensor and remote monitoring platform for managing NYHA class III heart failure.
Digital HealthHealthtechMedical DevicesWoodridge, US
Jonathan Jonas(Director)Harry Rowland(Executive Officer, Director)Raymond S. Barrett, Jr.(Director)Anthony I Nunez(Executive Officer, Director)Sam R. Leno(Director)Leslie A. Saxon(Director)
Board seatPaul LaViolette· per SEC Form D
HealthtechMinneapolis, US
Howard Levin(Director)Mark Christopherson(Executive Officer, Director)
BoardDavid Neustaedter(Director)Michael Hurley(Director)
Board seatPaul LaViolette· per SEC Form D
HealthtechSan Diego, US
John Buhler(Director)Rex Bright(Director)Martyn Gross(Executive Officer, Director)Kathy Scott(Executive Officer)David Hale(Director)
Board seatPaul LaViolette· per SEC Form D · $43M raise · filed Oct 2021
SpectraWave develops imaging and physiology technologies for coronary care, combining deep optical coherence tomography, near-infrared spectroscopy, and wire-free FFR measurements on a single platform to support percutaneous coronary intervention planning in catheterization laboratories.
AI & Machine LearningHealthtechMedical DevicesBedford, US
Eman Namati(Executive Officer, Director)Eric Swanson(Director)Martin Seifert(Executive Officer, Director)Steven Hochberg(Director)Guillermo Tearney(Director)
Board seatPaul LaViolette· per SEC Form D
BiotechPompano Beach, US
Virginia Sullivan(Executive Officer)Marc Loev(Director)Richard Chen Mao(Director)Gary Perryman(Director)Scott Sidwell(Executive Officer)Laura Tyler Perryman(Director)
Board seatPaul LaViolette· per SEC Form D · $8M raise · filed Sep 2020
Asensus Surgical (formerly TransEnterix) develops surgical robotics, advanced visualization, and instrumentation technology for surgeons.
HealthtechMedical DevicesRoboticsMorrisville, US
Anthony Fernando(Executive Officer)Paul A LaViolette(Director)Jane H Hsiao(Director)William N Kelley(Director)Andrea Biffi(Director)William, Jr. N Starling(Director)
Board seatPaul LaViolette· per SEC Form D
BiotechMaple Grove, US
MARY LINCOLN CAMPBELL(Director)MITCHELL DANN(Director)JON PATRICK ST. GERMAIN(Executive Officer)DAVID KRENN(Executive Officer)PAUL A. LAVIOLETTE(Director)JOHANN NEISZ(Executive Officer, Director)
Board seatPaul LaViolette· per SEC Form D
AdvanCell develops radioisotope-based therapies, using Th-228 sourced through the U.S.
BiotechHealthtechMedical DevicesCambridge, US
Philina Lee(Executive Officer, Director)Aaron Pickett(Executive Officer)Wing Cheong Lam(Director)Nik Economopoulos(Director)Anthony Aiudi(Director)Jamil Beg(Director)
HealthtechCalabasas, US
Michael Balmuth(Became Director as of July 8, 2016)Nitin Nanda, M.D.(Executive Officer, Director)John Eugene Hill(Became Director as of July 8, 2016)Deepak Chopra(Director)Vikram Marla(Resigned as director July 8, 2016)John Tadich(Became Director as of July 8, 2016)
Clinical-stage company developing novel treatment for recurrent high-grade gliomas
HealthtechChanhassen, US
Jeremy Ling(Executive Officer)Steve Weiner(Executive Officer)Vijay Agarwal(Executive Officer, Director)William Davis(Executive Officer, Director)
BoardKlaus Veitinger(Director)Imran Eba(Executive Officer)
BiotechLebanon, US
Kevin Isett(Executive Officer, Director)Claudio Nessi(Director)Warren Kett(Executive Officer)Jon Sheller(Executive Officer)Michael Ross(Director)Philip Ferneau(Director)
BardyDx develops the Carnation Ambulatory Monitor (CAM), a lightweight cardiac patch monitor designed for extended-wear ambulatory ECG monitoring that emphasizes P-wave signal clarity.
Digital HealthHealthtechMedical DevicesSeattle, US
Mark Querry(Executive Officer)Kevin Nelson, III(Executive Officer)Rik Vandevenne(Director)Gust H. Bardy(Executive Officer, Director, Promoter)Alan Levy(Director)Mark Handfelt(Executive Officer, Promoter)
Injectable Neural Ice™ for pain relief in osteoarthritis and hip pain
A pharmaceutical company that develops medicines and vaccines, with research, clinical trials, and a drug pipeline.
BiotechHealthtech
Browse all 206 investments with full details →
▶6 more tracked companies
VersicorVibrato MedicalViolet Therapeutics, Inc.Vitalize Consulting SolutionsXimedicaZerigo Health
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Exits · 10
IPOs and acquisitions across the tracked portfolioOcular TherapeutixNASDAQ: OCULAdaptHealthNASDAQ: AHCOAlectorNASDAQ: ALECAmerican WellNYSE: AMWLBicycle TherapeuticsNASDAQ: BCYCBioAgeNASDAQ: BIOACytomed TherapeuticsNASDAQ: GDTCInsuletNASDAQ: PODDXilio TherapeuticsNASDAQ: XLOCarawayacq. by Merck
Portfolio news
latest coverage across their companiesAdvanCell · intelligence360.news · Aug 4, 2026
Alector · dailypolitical.com · Jul 17, 2026
Quralis · nasdaqprivatemarket.com · Apr 3, 2026
Leiters · reuters.com · Oct 17, 2025
Fund performance · per public LP disclosures
as of Jun 2025| Fund | Vintage | Committed | Net IRR | TVPI | DPI |
|---|---|---|---|---|---|
| SV Health Investors Growth Fund VII bLPs: New Mexico Educational Retirement Board | 2024 | — | 0.0% | 0.00x | 0.00x |
Source: public limited-partner disclosures (CalPERS, CalSTRS). Net IRR / TVPI / DPI as reported by the limited partner; a fund's early-year IRR is an interim estimate (J-curve).
Frequently asked questions
- What stage does SV Health Investors invest at?
- SV Health Investors invests at the Pre-Seed, Seed, Series A, Series B, Series C, Growth, Late Stage stages.
- What is SV Health Investors's typical check size?
- SV Health Investors typically writes checks of $1M – $20M.
- What sectors does SV Health Investors focus on?
- SV Health Investors focuses on Biotech, Digital Health, Healthtech, Longevity, Medical Devices.
- Where is SV Health Investors located?
- SV Health Investors is headquartered in Boston, US.
- Does SV Health Investors lead rounds?
- Yes, SV Health Investors leads investment rounds.
Media · Podcasts & interviews
featuring the teamMedtech Venture Capital Insights with Paul LaViolette of SV Health Investors
State of MedTech · Paul LaViolette
Co-investors · 28
RA Capital invests in public and private healthcare and life science companies developing pharmaceuticals, medical devices, and diagnostic tools. The firm operates as a crossover fund across multiple investment stages.
Sanofi Ventures is the corporate venture capital arm of Sanofi, investing in early-stage biotech and digital health companies focused on improving human health. It serves as Sanofi's entry point into the innovation ecosystem.
Polaris Partners is a venture capital firm that partners with biotech and healthcare entrepreneurs to build transformational companies.
Ascension Ventures manages capital and presents itself as an investor connected to a large health system network, referencing hundreds of acute care hospitals and a substantial employee base.
Dolby Family Ventures is an investment firm focused on life sciences, backing companies across precision neuroscience and life sciences platforms.
Lightstone Ventures is a life sciences venture firm founded in 2012 that invests in biotech and medtech companies, backing founders translating scientific breakthroughs into therapies and medical technologies.
M Ventures is the corporate venture arm of Merck KGaA based in Darmstadt, Germany, operating from offices in Amsterdam, the US, and Israel. The firm invests globally across early-stage companies and spin-offs in areas aligned with Merck's core business, taking active roles in portfolio company development.
OrbiMed is a global healthcare-focused investment firm providing financing and operational support to companies across biopharmaceuticals, medical devices, digital health, diagnostics, and healthcare services.
B Capital Group is a global venture capital firm that backs founders from early to late stage, with dedicated stage-based funds and a portfolio spanning technology, healthcare, and energy and resilience sectors.
Atlas Venture is a life sciences venture capital firm with three decades of experience investing in and building biotech and medical innovation companies, including startups launched from its own incubator.
Summit Partners is a growth investing firm that backs category-leading companies across technology, healthcare and life sciences, and growth products and services, providing capital and resources to support their expansion.
Sofinnova Partners is a life sciences venture capital firm investing across the value chain from seed to later stage, with a focus on healthcare and sustainability. It backs companies in biopharma, medtech, digital medicine, agriculture and industrial processes.
▶16 more co-investors
Third Rock VenturesAbingworth7wire VenturesAisling CapitalSilversmith Capital PartnersMcKesson VenturesBain Capital VenturesSOSVUS Venture PartnersS32Pivotal Life SciencesSandbox IndustriesOmega FundsNew Leaf Venture PartnersBorealis VenturesJUXTAPOSE VENTURES
Firms observed investing alongside SV Health Investors, from public investor directories. Shared companies are the overlap with SV Health Investors's recorded portfolio.
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