Arboretum Ventures
Venture capitalMilwaukee ยท Pre-SeedโSeries A ยท 11 people tracked
Investment thesis
Arboretum partners with diverse teams in under-ventured geographies and sectors to identify and accelerate early-stage healthcare startups with transformational potential. The firm combines deep healthcare industry expertise and strategic guidance to help portfolio companies achieve capital-efficient growth and deliver superior returns to investors.
Source: firm website, verified Jul 21, 2026.
Team ยท 11 people
from the firm's websiteVenture partner at Arboretum since 2023 who previously spent over 20 years as an investing partner with Domain Associates focused on life science investments. Currently serves as board director at Esperion Therapeutics and brings extensive experience in both public and private biotech investing.
CEO of Fogarty Innovation with 30 years of experience in the medical device industry across private and public sectors. Previously Vice President and General Manager of Medtronic's Transcatheter Mitral Valve business, President and CEO of Twelve Inc. and Ardian Inc., and currently Vice Chairman of The Foundry medical device incubator.
Vice President, Global Head of Corporate and Business Development & Ventures for Medtronic with over 25 years in pharmaceutical, biotech and medical device industries. Has led and closed more than 60 transactions worth approximately $16 billion, and brings experience from Allergan, Watson Pharmaceuticals, Agilent Technologies, and Peregrine Pharmaceuticals.
Cynthia joined Arboretum in 2025 and brings nearly two decades of higher education experience from the University of Michigan, including five years as Executive Assistant to the Chief Health Officer and Associate Vice President for Health & Wellness, as well as coordination roles in public health response initiatives.
Chief Financial Officer at Optum Health responsible for strategic financial direction of value-oriented healthcare delivery businesses. Previously served as Director of Corporate Development at United Health Group leading M&A strategy, and as an investment banker in the Healthcare Group at Goldman Sachs covering biopharmaceutical clients.
Cardiologist, researcher and public health expert currently serving as Director and Global Head of Healthcare and Public Health Partnerships at Google Health and YouTube. Previously served as U.S. Deputy Assistant Secretary for Health in two administrations and held leadership roles at CVS Health, Aetna Foundation, and University of Florida School of Medicine.
Founder and principal of BioAdvisors LLC providing strategic consulting to life science, diagnostics, and genomics companies. Held executive leadership at Illumina from 2002 to 2016 as Senior Vice President and General Manager, and has served as founding CEO of Verogen and board member for multiple life science companies.
Recently retired from Medtronic where he held multiple executive leadership roles including Senior Vice President and Chief Medical and Scientific Officer. Previously founded and served as Chief Scientific Officer of the Harvard Clinical Research Institute, with expertise in clinical trial design and FDA regulatory processes.
Healthcare executive transitioning to executive consultant for the national Trinity Health System with 93 hospitals across 26 states. Previously served as Chief Clinical Officer of Trinity Health Michigan for nearly a decade and held other leadership roles including Governor-appointed board service and presidency of the Michigan Society of Anesthesiologists.
Serial entrepreneur with over 20 years of leadership in novel IVD product development and operations. Most recently served as COO of Strata Oncology; previously President & COO of NeuMoDx Molecular (acquired by QIAGEN in 2020) and co-founder of HandyLab (acquired by BD in 2009).
Nationally recognized health policy leader and former Director of CMS's Coverage and Analysis Group, where she led national coverage policy affecting over 65 million Medicare beneficiaries. Currently focuses on coverage and payment strategy for medical technologies at Rubrum Advising, and was named CMS Executive of the Year in 2022.
What they invest in
from 13 of 32 portfolio companiesHealthtech ร10Medical Devices ร10Digital Health ร5Biotech ร4Deep Tech ร4Enterprise Software ร2Advanced Manufacturing ร1Data & Infrastructure ร1
HQs:United Statesร2
Investments ยท 32 tracked
founders shown can be your intro pathAkadeum manufactures GMP-compliant ancillary materials for cell and gene therapy applications, specializing in microbubble-based negative selection products. The company serves research, clinical trial, and therapeutic manufacturing environments requiring regulated cell separation products.
Advanced ManufacturingBiotechDeep TechHealthtechMedical DevicesAnn Arbor, US
ArborMetrix provides a software platform for healthcare quality improvement that aggregates and analyzes patient data to help providers, payers, and health systems optimize clinical and financial performance, reduce adverse events, and improve outcomes. The platform enables real-time insights and predictive analytics to guide clinical decisions and operational efficiency.
Data & InfrastructureEnterprise SoftwareHealthtech
Avation Medical manufactures the Vivally System, an FDA-cleared wearable device that uses transcutaneous tibial nerve stimulation to treat overactive bladder and urge urinary incontinence in at-home 30-minute sessions. The device is prescribed by healthcare providers for patients seeking a non-invasive alternative to medications, injectables, or surgical implants.
Digital HealthHealthtechMedical DevicesValencia, US
BrightSpec develops spectraMRR, a molecular rotational resonance spectroscopy platform for rapid identification and quantitation of molecules in complex mixtures. The platform serves pharmaceutical, chemical, and consumer goods industries for applications including structure validation, residual analysis, and raw material characterization.
BiotechDeep TechMedical Devices
Rick Gordon(CEO)
Convergent Dental manufactures Solea, a CO2 laser system for dental procedures that operates at a novel 9.3-micron wavelength, enabling anesthesia-free and suture-free treatments across soft and hard tissues. The company serves dental practices looking to expand procedural capabilities, improve patient experience, and increase practice efficiency.
Enterprise SoftwareHealthtechMedical Devices
Greg LoPour(DDS)
Endogenex develops the pulsENDO system, an endoscopic medical device that applies pulsed electric field technology to the small intestine to reset metabolic signaling for people with type 2 diabetes. The company, founded in partnership with Mayo Clinic, is currently evaluating the investigational system in clinical trials.
HealthtechMedical Devices
Barham K. Abu Dayyeh(Co-inventor, pulsENDO system)
Francis Medical develops the Vanquish procedure, a medical device treatment for benign prostatic hyperplasia that uses radiofrequency energy to ablate prostate tissue. The device is designed for men seeking non-invasive treatment of enlarged prostate symptoms.
Digital HealthHealthtechMedical Devices
Hicuity delivers telemedicine solutions for clinical, staffing, and operational challenges in acute and critical care venues. The company serves healthcare facilities seeking flexible and scalable remote care delivery capabilities.
Digital HealthHealthtech
Jumpcode Genomics develops programmable endonuclease enzymes for next-generation sequencing and PCR applications. The company's technology enables researchers to remove uninformative sequences and improve data quality for genomics applications including single-cell analysis, microbiome characterization, and infectious disease detection.
BiotechDeep Tech
Koya Medical develops medical devices for lymphedema, chronic venous insufficiency, and deep vein thrombosis treatment. The company serves healthcare professionals and veterans.
HealthtechMedical Devices<UNKNOWN>
Motif Neuro develops neural devices to monitor and regulate mental health and performance, with an initial focus on treatment-resistant depression using bioelectronic implants called DOT that are deployed via outpatient procedure.
BiotechDigital HealthMedical Devices
Pharaoh Neuro develops Neurapheresisโข, a medical device platform for precision management of cerebrospinal fluid to restore balance and protect brain health in neurocritical patients, particularly those with subarachnoid hemorrhage from aneurysms or strokes.
Deep TechHealthtechMedical Devices<UNKNOWN>
Amaza Reitmeier(CEO)
SonarMD is a digital monitoring platform for patients with inflammatory bowel disease that uses validated questionnaires and proprietary algorithms to detect deteriorating gut health between clinical visits. The platform enables physicians and health plans to proactively intervene before disease flares, reducing emergency visits and hospitalizations while improving patient outcomes.
Digital HealthHealthtechMedical Devices
Frequently asked questions
- What stage does Arboretum Ventures invest at?
- Arboretum Ventures invests at the Pre-Seed, Seed, Series A stages.
- What sectors does Arboretum Ventures focus on?
- Arboretum Ventures focuses on Biotech, Digital Health, Healthtech, Medical Devices.
- Where is Arboretum Ventures located?
- Arboretum Ventures is headquartered in Milwaukee, US.
- Does Arboretum Ventures lead rounds?
- Yes, Arboretum Ventures leads investment rounds.
From the blog
visit blog โArboretum Ventures recently highlighted clinical milestones at its portfolio companies, including full enrollment completion at diabetes device firm Endogenex and first patient enrollment at cardiac rhythm management company AtaCor Medical. AI summary
Similar investors
B Capital is a venture capital firm managing over $12 billion in assets with a stage-based fund approach. The firm invests across early to late-stage companies in technology, healthcare, and energy & resilience sectors, with 200+ portfolio companies and 9 global offices.
Breyer Capital is a venture capital firm that invests in high-impact entrepreneurs with a strategic focus on companies leveraging artificial intelligence and machine learning to transform technology sectors globally.
DCVC is a deep tech venture capital firm with over a dozen years of experience backing entrepreneurs using computational approaches to solve trillion-dollar problems across industries including AI, climate, materials science, robotics, space, and biology.
Innovestor is a Finnish investment manager that operates across venture capital, real estate, and energy storage sectors. The firm invests in early-stage technology and life science startups, energy-efficient commercial real estate, and battery storage and solar solutions. Innovestor also provides corporate venturing advisory services.
An early-stage venture capital firm investing in technology founders building solutions across multiple sectors.