Fundraising Fox
Ann Arbor · Seed–Series A · 28 people tracked
Also known as ARBORETUM VENTURES, LLC
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Investment thesis
Arboretum Ventures pursues a strategy of investing in under-ventured geographies and sectors within healthcare, backing early-stage startups that address significant healthcare problems in a capital-efficient manner. The firm targets medical devices, life science tools and diagnostics, tech-enabled care delivery, and pharma adjacencies, seeking teams that are diverse in thought, geography, and demographics. It emphasizes transparency, integrity, and approachability, aiming to improve patient outcomes and reduce healthcare costs while delivering strong returns to investors. Rooted in the Midwest, the firm has operated for over two decades and directs a majority of its portfolio toward under-ventured markets.
Source: firm website, verified Sep 29, 2026.
Team · 28 people
from the firm's website & public directories
Founder mafia
2 people who came through Arboretum Ventures went on to found or lead other companies.
What they invest in
from 47 of 71 portfolio companiesHealthtech ×34Medical Devices ×29Biotech ×20Digital Health ×15Hardware ×11Deep Tech ×7AI & Machine Learning ×5SaaS ×4
HQs:United States×46United Kingdom×1
Who they back
founder profiles across 24 portfolio companiesFounding team size:solo founder×192 founders×23 founders×3
What their founders studiedfrom 10 founders with field-of-study data
Life Sciences ×3Business & Management ×2
Investments · 71 tracked
founders shown can be your intro pathBy year:2026 · 32025 · 32024 · 32022 · 42021 · 42020 · 42019 · 42018 · 42017 · 32016 · 52015 · 52014 · 246 dated
Shoulder Innovations develops InSet® glenoid technology for shoulder joint implants that reduce the rocking horse effect and provide mechanical stability, serving patients with severe shoulder arthritis.
HardwareHealthtechMedical DevicesNorthern California, US
Robert Ball(CEO & Executive Chairman)Matthew Ahearn(Chief Operating Officer)inJeff Points(Executive Officer)inDon Running(Manager and Chief Executive Officer)Jeff Ondrla(Chief Technology Officer)David L. Blue(Chief Customer Experience Officer)in
Co-investorsAlumni VenturesAPERTURE Venture PartnersGenesis Innovation GroupGlobal BrainInvest MichiganLightstone Ventures+3 more
SI-BONE develops medical devices for treating sacroiliac (SI) joint dysfunction and chronic low back pain, targeting patients and physicians.
HealthtechMedical DevicesSan Jose, US
Mark Reiley(Director)inJeffrey W. Dunn(Executive Officer, Director)Robert E. Johnson(Executive Officer)Dan Murray(Executive Officer)Laura A. Francis(Chief Executive Officer)
BoardTimothy E. Davis(Director)
PartnerTim Petersen· led
Co-investorsMontreux Equity PartnersOrbiMed
Convergent Dental is a privately owned dental equipment and technology company whose flagship product, Solea, is a CO2 all-tissue laser cleared by the FDA that offers anesthesia-free, blood-free, and suture-free dental procedures.
Enterprise SoftwareHardwareHealthtechMedical DevicesNatick, US
Nathan P. Monty(Executive Officer, Director)inMichael J. Cataldo(Executive Officer, Director)Rob Gershon(Chief Executive Officer)inMark Collins(Chief Financial Officer)inTodd Hornsby(Chief Commercial Officer)in
BoardBart Doedens(Director)
Board seatTimothy PetersenTimothy B. Petersen· per SEC Form D
Co-investorsLRVHealthTrinity Capital
Boomerang Medical develops a bioelectric neuromodulation device to treat bowel urgency symptoms in patients with ulcerative colitis and other inflammatory bowel disease.
BiotechDigital HealthMedical DevicesMountain View, US
Co-investorsHatteras Venture Partners
Orasis is a pharmaceutical company developing drugs for the eye, operating in the ophthalmology and eyecare space.
BiotechHealthtechMedical Devices
Co-investorsMaverick Ventures IsraelVisionary VenturesCatalio Capital ManagementJohnson & Johnson Innovation – JJDCLifeSci Venture PartnersSequoia Capital+1 more
PAK BioSolutions builds automated systems and single-use flow kits for end-to-end continuous purification of biopharmaceuticals, running four continuous purification stages simultaneously for a stated 4X productivity gain over batch methods.
Advanced ManufacturingBiotechHardwareBurke, US
Pezzini Joanna(President)inKevin Hill-Byrne(Co-Founder & CTO)in
Co-investorsBroadOak Capital Partners
HealthtechSt Louis, US
Andrea M. Clegg(Executive Officer)Louis Silverman(Executive Officer, Director)
BoardBarbara Lubash(Director)inMichael Mikolajczyk(Director)David N. Schopp(Director)
Board seatTimothy B. Petersen· per SEC Form D · $7.3M raise · filed Jul 2015
Co-investorsVersant Ventures
Allay Therapeutics develops localized pain management technology designed to deliver several weeks of post-surgical pain relief.
BiotechHealthtechMedical DevicesSan Jose, US
Adam Gridley(Executive Officer, Director)inKristen Howells(Executive Officer)inJosh Makower(Director)Tak Cheung(Director)inKarun D. Naga(Executive Officer, Director)
BoardLeighton Read(Director)
Board seatPaul McCreadie· per SEC Form D
Co-investorsLightstone VenturesNew Enterprise Associates (NEA)SGInnovateClavystBioEvonik Venture Capital GmbH
ArborMetrix provides a software platform for healthcare quality improvement that aggregates and analyzes patient data to help providers, payers, and health systems optimize clinical and financial performance, reduce adverse events, and improve outcomes.
Data & InfrastructureEnterprise SoftwareHealthtechAnn Arbor, US
John Birkmeyer, M.D.(Director)Brett Furst(Executive Officer, Director)inChristian Birkmeyer(Executive Officer)Steven Richvalsky(Executive Officer)
BoardPaul McCreadie(Director)inAnthony Grover(Director)
Board seatTimothy Petersen· per SEC Form D
Co-investorsID Ventures
Francis Medical is a medical device company developing minimally invasive urological cancer treatments using water vapor ablation technology, initially focused on prostate cancer with its Vanquish Water Vapor Ablation System.
BiotechDigital HealthHealthtechMedical DevicesMaple Grove, US
Michael Hoey(Founder)inMichael Kujak(Executive Officer, Director)Christopher Dixon(Chief Medical Officer)in
BoardAndrew Cleeland(Director)David Adair(Director)in
Board seatJan Garfinkle· per SEC Form D
Co-investorsSolas BioVentures
Health Scholars (UpSkillAI) provides AI- and XR-based immersive training, using voice-powered VR simulations that let teams practice protocols hands-free.
AI & Machine LearningEdTechFuture of WorkWestminster, US
BRIAN GILLETT(Executive Officer)ROBERT SEHRING(Director)ANGELA MCFARLAND(Executive Officer)SCOTT JOHNSON(Executive Officer, Director)LAURA MEDINA(Executive Officer)RIKARD STEIBER(Director)
Board seatThomas Shehab· per SEC Form D
Co-investorsCapital Midwest FundService Provider CapitalClarevia Ventures
Koya Medical develops wearable compression therapy devices, including its Dayspring system, for treating conditions such as lymphedema, chronic venous insufficiency, and deep vein thrombosis.
HardwareHealthtechMedical DevicesOakland, US
Anand Doraiswamy(Executive Officer, Director)in
BoardJosh Baltzell(Director)in
Board seatJan Garfinkle· per SEC Form D
Co-investorsAphelion CapitalScientific Health DevelopmentZühlke VenturesAsahi Kasei Corporate VenturesCadence Healthcare VenturesOrbiMed
Motif Neurotech develops a therapeutic brain-computer interface using minimally invasive neuromodulation to treat difficult-to-treat mental health conditions such as depression.
BiotechDeep TechDigital HealthHealthtechMedical DevicesHouston, US
Sameer Sheth(Founder)inSunil Sheth(Founder)Nick Halper(Chief Operating Officer)inSteve Goetz(Chief Technology Officer)inAnthony Arnold(Director)inKaiyuan Yang(Founder)
Board seatThomas M. Shehab· per SEC Form D
Co-investorsDivergent CapitalDolby Family VenturesFeatures Capital HoldingsPsyMed VenturesTMC Venture FundXEIA Venture Partners+6 more
Pioneering the development of prescription digital therapeutics.
HealthtechBoston, US
Corey McCann(Executive Officer, Director)inAntoun Nabhan(Executive Officer)Christopher Guiffre(Executive Officer)
BoardAndrew Schwab(Director)inZack Lynch(Director)in
Board seatTimothy PetersenTim Petersen· per SEC Form D · $51M raise · filed Jan 2018
Co-investorsJAZZ Venture Partners5AM VenturesGeneral CatalystOCA VenturesSeyen CapitalSoftBank Group+2 more
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Seattle, US
Ronald Seubert(Executive Officer, Director, Promoter)Evan Castiglia(Executive Officer)inJoseph Victor(Executive Officer, Director)Frank Witney(Director)Eric Kaldjian(Executive Officer)
BoardRobert Shepler(Director)in
Board seatJan Garfinkle· per SEC Form D
Co-investors5AM VenturesF-Prime CapitalTelegraph Hill PartnersHealthQuest CapitalSofinnova Ventures
Reprieve Cardiovascular develops a decongestion management system that uses real-time patient data to guide and personalize diuretic therapy for fluid removal in heart failure patients.
Digital HealthHealthtechMedical DevicesMilford, US
Tony Fields(Executive Officer)Adam Bartnik(Executive Officer)inMark Pacyna(Executive Officer, Director)inJim Dillon(Executive Officer, Director)Hanson S. Gifford III(Director)Gregory W Mann(Executive Officer)
Board seatJan Garfinkle· per SEC Form D
Co-investorsLightstone VenturesRex Health VenturesDeerfield Management CompanyGenesis Venture CapitalSante Ventures
Strata Oncology develops precision oncology biomarkers and predictive diagnostic tools for cancer treatment, including treatment response scores for antibody-drug conjugates (ADCs) and an Immunotherapy Response Score for anti-PD-1/PD-L1 therapies.
AI & Machine LearningBiotechDigital HealthMedical DevicesAnn Arbor, US
Daniel Rhodes(Executive Officer, Director)Matthew Martin(Executive Officer)Jeffrey Williams(Executive Officer, Director)
BoardChristopher O'Donnell(Director)inDavid Rubin(Director)inJames Pavlik(Director)in
Board seatJan GarfinkleNicole Walker· per SEC Form D
Co-investorsBaird CapitalMerck Global Health Innovation FundMSD Global Health Innovation FundPfizer Venture InvestmentsWellington ManagementDeerfield Management Company+1 more
SonarMD provides a care management platform for chronic diseases, starting with gastroenterology, that combines AI technology with human support to detect clinical deterioration early and help specialists intervene before emergencies.
AI & Machine LearningDigital HealthHealthtechMedical DevicesSaaSChicago, US
Lawrence R. Kosinski(Founder and Board Member)inBETH HOUCK(Executive Officer, Director)inJohn Starr(Executive Officer)Devin Gross(Executive Officer, Director)
Board seatCharity TarnThomas M ShehabTom Shehab· per SEC Form D
Co-investorsBlue Hour VenturesHypothesisNueterra CapitalTensility Venture PartnersBlueCross BlueShield Venture Partners
ViaLase develops the ViaLase Laser System, a femtosecond laser and HD imaging platform for noninvasive interventional glaucoma treatment that creates apertures through the trabecular meshwork in patients with open-angle glaucoma.
Deep TechHealthtechMedical DevicesAliso Viejo, US
Tibor Juhasz(Executive Officer, Director)inRick Lewis(Executive Officer)Scott Cooper(Executive Officer)Hadi Srass(Executive Officer)inShawn O'Neil(Executive Officer)in
BoardWilliam Link(Director)
Board seatTim Petersen· per SEC Form D
Co-investorsVersant Venture AIV Holdings
Virtual Incision develops a miniaturized robotic-assisted surgery (miniRAS) system called MIRA, designed to fit within hospitals' existing infrastructure.
BiotechHealthtechMedical DevicesRoboticsLincoln, US
Dmitry Oleynikov(Director)Shane Farritor(Executive Officer, Director)John P. Murphy(Executive Officer, Director)inMukund Srinivasan(Executive Officer)inJames M. Alecxih(Executive Officer, Director)Robert Larid(Executive Officer)
Board seatTom Shehab· per SEC Form D
Co-investorsBaird CapitalEndeavour VisionInvest NebraskaInVivium CapitalPrairieGold Venture Partners
410 Medical makes LifeFlow, a hand-operated rapid infuser that lets clinicians quickly deliver blood or fluids to critically ill patients needing volume resuscitation.
HardwareHealthtechMedical DevicesDurham, US
Mark Donald Piehl(Executive Officer, Director)KYLE CHENET(Executive Officer, Director)in
BoardJEFF TERRELL(Director)inSTANLEY D. LYNALL(Director)FRED GOLDWATER(Director)inMAYANK TANEJA(Director)in
Co-investorsBallad VenturesCU Healthcare Innovation FundDuke Capital PartnersOSF VenturesWellstarWolfpack Investor Network+2 more
Abra provides a digital asset platform for private and institutional clients, offering services across decentralized finance, asset management, and credit with a focus on security and regulatory compliance.
Crypto & Web3FintechSaaS
Bill Barhydt(Founder & CEO)in
Co-investorsAccelerator VenturesAngel Collective Opportunity FundArbor VenturesBitfuryBlockchain CapitalDigital Currency Group+14 more
Akadeum manufactures GMP-compliant ancillary materials for cell and gene therapy applications, specializing in microbubble-based negative selection products.
Advanced ManufacturingBiotechDeep TechHealthtechMedical DevicesAnn Arbor, US
Kalyan Handique(Executive Officer, Director)John Younger(Executive Officer, Director)inJames Militello(Executive Officer)
BoardJeffrey S. Williams(Director)Paul D'Amato(Director)inDan Kidle(Director)in
Co-investorsBeringeaBerkeley CatalystBlueStone Venture PartnersCANTILEVER INVESTORSeLab VenturesHemisphere Ventures LLC+7 more
AtaCor Medical develops extravascular lead systems for cardiac rhythm management, including a novel extravascular defibrillation lead for EV-ICD therapy and an implantable, extracardiac pacemaker.
HardwareHealthtechMedical Devices
Alan(Co-founder & Vice President of Clinical, Regulatory & Quality)
Co-investorsBayMed Venture PartnersBroadview VenturesCatalyst Health VenturesHatteras Venture Partners
Avation Medical manufactures the Vivally System, an FDA-cleared wearable device that uses transcutaneous tibial nerve stimulation to treat overactive bladder and urge urinary incontinence in at-home 30-minute sessions.
Digital HealthHealthtechMedical DevicesValencia, US
Manish Vaishya, PhD(Chief Executive Officer, Co-Founder & Board Member)Jill Schiaparelli(Executive Officer, Director)inKevin Wasserstein(Director)
BoardThomas Shehab, MD(Director)
Co-investorsAngelini VenturesAsahi Kasei Corporate Venture CapitalAvestria VenturesShangBay Capital LLC
Non-surgical, non-pharmacologic devices to induce weight loss
Co-investorsDelos CapitalLongitude CapitalHighland Capital PartnersSante Ventures
Digital HealthHealthtechMedical DevicesSanta Barbara, US
Justin Bellante(Executive Officer, Director, Promoter)Brent Peus(Executive Officer)
BoardBrandon Cady(Director)Jeff Closs(Director)Patrick Cua(Director)Kathleen Shanahan(Director)
PartnerPaul McCreadie· led
Co-investorsHealthQuest Capital
BrightSpec develops molecular rotational resonance (MRR) spectroscopy instruments and software that identify and quantify gas-phase molecules from complex mixtures without front-end separation.
BiotechDeep TechHardwareWaltham, US
Rick Gordon(CEO)inWalter Colsman(Executive Officer, Director)JAFFRAY WOODRIFF(Director)ROBERT LLOYD(Executive Officer, Director)THOMAS JONES(Director)DAVID MCDANIEL(Executive Officer, Director)
Co-investorsGenoa VenturesMedvest Capital
Cardiosense develops wearable sensing hardware and deep-learning algorithms that convert physiological signals into clinical insights for cardiovascular disease detection and management.
AI & Machine LearningDigital HealthHealthtechMedical DevicesChicago, US
Amit Gupta(Co-founder, Advisor)inMozziyar Etemadi(Co-founder, Head of AI)Omer Inan(Co-founder, Chief Scientific Officer)inAndrew Carek(Co-founder, Chief Technical Officer)inEric Meizlish(Chief Executive Officer)inJohn D. Martin(Chief Medical Officer)in
Co-investorsBayMed Venture PartnersBroadview VenturesCross-Border Impact VenturesLaerdal Million Lives FundOSF VenturesPortal Innovations+1 more
ConcertoCare provides coordinated in-home and center-based medical, behavioral, and social care for seniors and adults with complex care needs who have Medicare, Medicare Advantage, or Medicare+Medicaid coverage.
Digital HealthHealthtechLongevity
Co-investorsAtento CapitalObvious VenturesSteelSky VenturesAddeparDeerfield Management CompanyVast Ventures+1 more
Endogenex is a clinical-stage medical device company developing the pulsENDO system, which applies non-thermal pulsed electric field to reset the body's metabolic signaling and improve function in people with type 2 diabetes.
Digital HealthHealthtechMedical DevicesMinneapolis, US
Stacey Pugh(Leadership (CEO))inChris Sorli, MD, PhD(Chief Medical Officer)inKrissy Wright(Chief Financial Officer)inLian Cunningham, MD, PhD(VP Clinical Affairs)inMelanie Hess(Regulatory Affairs Leadership)inMatt Cambronne(Technical/Engineering Leadership)in
Co-investorsHatteras Venture PartnersIntuitive VenturesLongitude CapitalLumira VenturesSoutheast Minnesota Capital Fund
Enumera Molecular develops technology and a platform for simplified, lower-cost workflows that enable liquid biopsy and high-dimensional omics assays for laboratories.
BiotechDeep TechHealthtechMedical DevicesAnn Arbor, US
Matthew Cooper(CEO & Co-founder)inElaine Heron(Director)
BoardDan Kidle(Director)inSundaresh Brahmasandra(Director)
Co-investorsStartX
EQRx was a Cambridge, MA biopharma that aimed to sell lower-priced novel drugs; it was acquired by Revolution Medicines in 2023.
Alexis Borisy(Founder)
Co-investorsAndreessen HorowitzARCH Venture PartnersGV (Google Ventures)Nextech InvestBain CapitalCasdin Capital+1 more
Biopharma developing HDL-C regulating therapies; listed 2000.
BiotechAnn Arbor, US
Roger S. Newton(Director)inTim M. Mayleben(Executive Officer, Director)
BoardDaniel Janney(Director)Dov A. Goldstein(Director)Nicole Vitullo(Director)inPatrick Enright(Director)in
Co-investorsAisling CapitalAlta PartnersARCHIMED JapanAsset Management CompanyCanaan PartnersHealthCap+3 more
Software that detects subtle vital-sign changes to warn medical professionals of post-operative patient deterioration risk.
Jen Baird, NACD.DC(Founder)inMark Salamango(Founder)in
Co-investorsInvest MichiganWMU Biosciences Research & Commercialization CenterCultivation Capital
Flosonics Medical makes FloPatch, a wireless wearable Doppler ultrasound device that assesses a patient's carotid arterial pulse in real time to give clinicians hemodynamic data for fluid resuscitation decisions.
Digital HealthHardwareMedical Devices
Joe Eibl(Founder)in
Co-investorsAmplify CapitalGenesys CapitaliGan PartnersNew Leaf Venture PartnersRBCx
Hicuity Health is an independent provider of acute and critical care telemedicine services, including tele-ICU, in-patient telemetry monitoring, virtual nursing, virtual sitter, and smart device monitoring.
Digital HealthHealthtechMedical DevicesSt. Louis, US
Isabelle Kopec(Co-founder)Lou Silverman(Chairman & CEO)inAndrea Clegg(CFO & Compliance Officer)inJason Kressel(Chief Operating Officer)inSergio Piñon(Head of Enterprise Clinical Applications)inCorey Danko(Head of IT Infrastructure)in
PartnerTim Petersen· led
Co-investorsCorewell Health Ventures
HistoSonics develops histotripsy technology, a non-invasive method that uses focused sound energy to destroy targeted tissue, offered as a medical device for physicians and their patients.
BiotechHardwareHealthtechMedical DevicesAnn Arbor, GB
Thomas Davison(Executive Officer, Director)inM. Christine Gibbons(Executive Officer, Director)inWen Chen(Director)Tom Tefft(Director)Michael Blue(Executive Officer, Director)Fred Lee(Director)
Co-investorsAlpha Wave GlobalAmzak HealthEarly Stage Partners, LPHealthQuest CapitalK5 GlobalLumira Ventures+7 more
Inogen is a global medical technology company that develops, manufactures, and markets portable oxygen concentrators and other respiratory therapy devices for home use.
Digital HealthHardwareHealthtechMedical Devices
Ali Bauerlein(Founder)in
Intellicyt (now part of Sartorius) develops the iQue high-throughput screening (HTS) flow cytometry platform, which combines sampling hardware and analysis software to generate multiplexed cell phenotype and function data from 96- or 384-well plates.
BiotechHardwareMedical Devices
Co-investorsProlog VenturesSaba Investments
Jumpcode Genomics develops CRISPRclean, a next-generation sequencing technology that removes abundant, uninformative sequences to improve sensitivity, lower costs, and simplify workflows for researchers.
AI & Machine LearningBiotechDeep TechHealthtechSan Diego, US
David Michael Salter(Executive Officer, Director)Mike Salter(CEO/President)inEugene Chen(Director)Keith Brown(Executive Officer, Director)Joel Rotroff(Director)
BoardCourt Turner(Director)
Co-investorsBaird CapitalGlobal Health Investment CorporationLYZZ Capital
LoanStreet operates an online platform for loan trading, syndication, and portfolio management serving credit unions, banks, and direct lenders.
B2B MarketplacesEnterprise SoftwareFintechSaaSNew York, US
Christopher Wu(Executive Officer, Director)Thaddeus Pitney(Executive Officer)Ian Lampl
Co-investorsArbor VenturesCurql Collective, LLCNext Level VenturesPortage VenturesRosecliff VenturesThird Prime
Exit: Acquired by Experian Health, August 2019.
Nashville, US
Lance Fusacchia(Executive Officer)inThomas Cox(Executive Officer, Director)Susan Brownie(Executive Officer)in
BoardJay C. Mason(Director)Timothy Petersen(Director)David Jones, Jr.(Director)in
Co-investorsChrysalis Ventures
HealthStream's Nursegrid Unlimited CE is a subscription service offering nurses unlimited access to continuing education courses that meet state-specific regulatory requirements for nursing practice compliance.
ConsumerDigital HealthEdTechFuture of WorkHealthtechHR TechSaaS
Co-investorsExcelerate Health VenturesHatteras Venture PartnersPortland Seed FundToba CapitalHEALTHBOX
Pharaoh Neuro is a neurotechnology company focused on protecting and restoring brain health, with an emphasis on the fluids surrounding the brain such as cerebrospinal fluid.
BiotechDeep TechHealthtechMedical Devices
Mark Wagner(Founder, Investor, & Director in Pharaoh)inDr. Nandan Lad(Chief Medical Officer & Co-Founder)Rich Nazarian(Founder, Investor, & Director in Pharaoh)inAmaza Reitmeier(Chief Executive Officer, Director)in
Co-investorsHatteras Venture PartnersIAG Capital PartnersLaerdal Million Lives Fund
Uptake Medical is a medical device company developing Bronchoscopic Thermal Vapor Ablation, a non-surgical, non-implant therapy that applies heated water vapor to ablate diseased lung tissue.
BiotechHealthtechMedical DevicesTustin, US
Robert Barry(Executive Officer, Promoter)Krista Mann(Executive Officer)R. King Nelson(Executive Officer, Director)in
BoardCarl Simpson(Director)David Singer(Director)inGeoff Brooke(Director)
Co-investorsGBS Venture Partners Ltd.Maverick CapitalMaverick VenturesWRF Capital
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Aira TechCervilenzConcerto HealthcareNvision MedicalNxthera IncTangent Medical TechnologiesTrove AnalyticsAccuri CytometersAkulaku GroupAtacorDelphinus Medical TechnologiesDropworksGlobaliDHandyLabHealthMediaLucina HealthMarkable Creators(Markable AI)NeuMoDxQuanChengReprieve MedicalRethinkSonitus MedicalSwift BiosciencesVasoNova
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Exits · 7
2 IPOs · 5 acquisitions · showing 4Shoulder InnovationsNYSE: SISI-BONENASDAQ: SIBNBioIQacq. by LetsGetCheckedIntelliCytacq. by Sartorius
Portfolio news
latest coverage across their companiesSI-BONE · finance.yahoo.com · Aug 3, 2026
Pharaoh Neuro · pharaohneuro.com · Jul 23, 2026
410 Medical · finsmes.com · Jul 14, 2026
Esperion Therapeutics · stocktitan.net · Jun 8, 2026
Shoulder Innovations · prnewswire.com · May 13, 2026
Koya Medical · biospace.com · May 12, 2026
Endogenex · endogenex.com · Mar 26, 2026
Reprieve Cardiovascular · finance.yahoo.com · Aug 14, 2025
IPO stake values · per SEC filings · 2
Value of this firm's stake in each portfolio company at its IPO price, from the prospectus principal-stockholder table.
| Company | Owned | IPO price | At IPO | Stake value |
|---|---|---|---|---|
| SI-BONE | 7.4% | $15.00 | Oct 2018 | $25.4M |
| Shoulder Innovations | 4.9% | $15.00 | Aug 2025 | $15M |
Source: SEC S-1 / 424B prospectus filings. Stake value = shares beneficially owned × the initial public offering price, as disclosed — a market value at IPO, not a return multiple (the firm's original cost is not disclosed).
Frequently asked questions
- How many investments has Arboretum Ventures made?
- Arboretum Ventures has 71 tracked investments, 7 of which have exited, including 6 dated in the last 24 months.
- What stage does Arboretum Ventures invest at?
- Arboretum Ventures invests at the Seed, Series A stages.
- What is Arboretum Ventures's typical check size?
- Arboretum Ventures typically writes checks of $5M – $15M.
- What sectors does Arboretum Ventures focus on?
- Arboretum Ventures focuses on Biotech, Digital Health, Healthtech, Medical Devices.
- Where is Arboretum Ventures located?
- Arboretum Ventures is headquartered in Ann Arbor, US.
- Does Arboretum Ventures lead rounds?
- Yes, Arboretum Ventures leads investment rounds.
- Who does Arboretum Ventures co-invest with?
- Arboretum Ventures most often shares deals with Hatteras Venture Partners, Western Technology Investment, Baird Capital, among 97 tracked co-investors.
From the blog
visit blog ↗Arboretum Ventures recently highlighted clinical milestones at its portfolio companies, including full enrollment completion at diabetes device firm Endogenex and first patient enrollment at cardiac rhythm management company AtaCor Medical. AI summary
Media · Podcasts & interviews
featuring the teamJan Garfinkle – Arboretum Ventures (Manager Meetings, EP.09)
Capital Allocators with Ted Seides · Jan Garfinkle
Co-investors · 33
Hatteras Venture Partners is a venture capital firm focused on early-stage life sciences and healthcare companies, backing therapeutics, diagnostics, and businesses aiming to transform healthcare delivery and innovation.
Lightstone Ventures is a life sciences venture firm founded in 2012 that invests in biotech and medtech companies, backing founders translating scientific breakthroughs into therapies and medical technologies.
HealthQuest Capital is a healthcare-focused investment firm that backs transformative healthcare companies, primarily at the commercial stage, through Growth Equity and Tactical Opportunities strategies.
F-Prime Capital is an early-stage-focused investment firm backing companies across life sciences, technology, healthtech and services, and crypto.
5AM Ventures is a life science venture capital firm founded in 2002 that funds and builds next-generation life sciences companies, focusing on biopharmaceuticals, drug delivery technologies, and life science instruments.
Broadview Ventures is an impact investor focused on accelerating the development of technology for the diagnosis and treatment of cardiovascular disease and stroke through targeted investments.
Santé is a healthcare-focused investment firm that manages over $1 billion across venture and public-market strategies. Through Santé Ventures it backs private healthcare startups, and through Santé Capital it runs a liquid hedge fund strategy using proprietary data-science software.
Beringea is a transatlantic venture capital firm that partners with entrepreneurs to scale high-growth businesses, drawing on funds and networks in both the U.S. and the U.K.
Sequoia Capital is a venture capital firm that partners with founders to build technology companies.
GV (Google Ventures) is a venture capital firm that has invested in AI and machine learning since its early days, backing more than 100 AI companies across infrastructure, life sciences, and applications.
New Enterprise Associates (NEA) is a venture capital firm that invests in and provides long-term support to founders building new companies.
RRE Ventures is a boutique early-stage venture capital firm that backs founders across sectors, combining decades of experience with AI-driven analysis throughout the investment lifecycle.
▶21 more co-investors
US Venture PartnersBlockchain CapitalDigital Currency GroupAccelerator VenturesFuture Perfect VenturesIGNIAJungle VenturesParallax VenturesSolas BioVenturesB Capital GroupLiquid VenturesGoodwater CapitalAltaIR CapitalCompany CapitalAmerican Express Ventures (Amex)305 VenturesPitbull VenturesGSR VenturesNKM CapitalArcus VenturesPerseverance Capital
Firms observed investing alongside Arboretum Ventures, from public investor directories. Shared companies are the overlap with Arboretum Ventures's recorded portfolio.
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