Two Sigma Ventures
Venture capitalNew York · Seed–Series B · 16 people tracked
Also known as Two Sigma Ventures Maple
Investment thesis
Originating from a quantitative hedge fund, they use quant models and embed data scientists, engineers, and researchers to tackle ML and data-pipeline challenges for AI, software infrastructure, and hardtech.
Source: firm website, verified Aug 3, 2026.
Team · 16 people
from public directories
What they invest in
from 19 of 25 portfolio companiesEnterprise Software ×8AI & Machine Learning ×7SaaS ×5Biotech ×3Consumer ×3Data & Infrastructure ×3Developer Tools ×3Medical Devices ×3
HQs:United States×22
Investments · 25 tracked
founders shown can be your intro pathEnergySacramento, US
Michael Max Buhler(Director)Carl Stanton(Director)Sunny Trinh(Chief Executive Officer)Jamila Piracci(Director)Wray Thorn(Director)Stephen Kukucha(Director)
Board seatWray Thorn· per SEC Form D · $2M raise · filed Dec 2025
EnergyHouston, US
William Dale Dale(Chief Financial Officer)Carter McCain(Director)Christopher Cooper(Chief Executive Officer)Si-Yeon Kim(Director)Sanford Cockrell(Director)Wray Thorn(Director)
Board seatWray Thorn· per SEC Form D · $10M raise · filed Feb 2026
Flatfile provides a platform for automating data onboarding, mapping, transformation, and validation using AI-guided workflows.
AI & Machine LearningData & InfrastructureEnterprise SoftwareDenver, US
AVERY CHASE(Executive Officer, Director)FRANCES SCHWEIP(Director)David Boskovic(Executive Officer, Director)Eric Crane(Executive Officer, Director)
BoardRORY O'DRISCOLL(Director)
Hyper provides avatar and AI storytelling tools that enable consumers to create their own content and experiences, positioning itself in the creator economy space.
AI & Machine LearningConsumerCreator EconomyMedia & EntertainmentSocialSan Francisco, US
Aaron Ng(Founder/CEO)inLevanJimAndrew Breckenridge(Executive Officer, Director)
Isabl develops whole genome and transcriptome sequencing technology for cancer diagnosis, delivering comprehensive genomic profiling and treatment options to physicians and research teams.
BiotechDigital HealthHealthtechMedical DevicesNew York City, US
Juan Medina(Founder)inAndrew Kung(Founder)inElli Papaemmanuil(Founder)in
Hawthorne, US
Erik Palitsch(Executive Officer, Director, Promoter)Thomas J. Ronacher(Executive Officer, Director)
BoardMohammad Islam(Director)Keith Dunleavy(Director)
Board seatDusan Perovic· per SEC Form D · $67.1M raise · filed Jan 2026
Bee Cave, US
Board seatDusan Perovic· per SEC Form D · $44M raise · filed Aug 2025
Odeko provides software and operational systems for independent food service businesses to compete with chain restaurants through cost optimization and margin improvement.
Enterprise SoftwareFoodTechLogistics & Supply ChainRetail TechSaaSNew York City, US
James Burkhardt(Founder)inDane Atkinson(Chief Executive Officer)Tom Hore(Chief Product Officer)Stephen Mar(Chief Legal & Administrative Officer)Allen Duan(Director)Chris Goulakos(Director)
Board seatDan Abelon· per SEC Form D · $49.5M raise · filed Jan 2022
Boston, US
Board seatWray Thorn· per SEC Form D · $30.2M raise · filed Mar 2018
Newport Beach, US
Arthur R. Schmidt(Executive Officer)Bryan Billings(Executive Officer)Cesar Romero-Aguilar(Executive Officer)Loren M. Dollet(Executive Officer)J. Chandler Martin(Director)Jason Cipriani(Director)
Board seatWray T. Thorn· per SEC Form D · filed Jun 2019
Arda develops therapeutics using single-cell computational biology to target and eliminate pathogenic cells in chronic diseases.
AI & Machine LearningBiotechMedical DevicesAustin, US
Adam Freund(Founder & Chief Executive Officer)Remi-Martin Laberge(Founder and Chief Technology Officer)
BoardVineeta Agarwala(Director)
Seattle, US
Amy McCullough(Director)Greg Gottesman(Director)Brad Feld(Director)Xiao Wang(Executive Officer, Director)
An insurance brokerage offering personalized policy solutions for small businesses across multiple sectors including healthcare providers, attorneys, dentists, and nonprofits.
InsurTechNew York, US
Inaki Berenguer(Executive Officer, Director)
BoardCharles Moldow(Director)John Buttrick(Director)
MonetizeNow provides a unified platform combining configure-price-quote (CPQ), billing, and metering capabilities for SaaS businesses.
Enterprise SoftwareFintechSaaS
Sandeep(Founder / CEO)
Okteto is a developer platform that enables teams to develop cloud-native applications by moving development and preview environments into the cloud.
AI & Machine LearningCloud ComputingData & InfrastructureDeveloper ToolsEnterprise SoftwareSaaSSan Francisco, US
Ramiro Berrelleza(Founder)inPablo Chico de Guzman(Founder/CTO)inRamon Lamana(Founder)inRamiro Antonio Berrelleza Perez(Executive Officer, Director, Promoter)
RentHop is an apartment rental marketplace that connects renters with listings ranked by freshness, accuracy, and property manager responsiveness, while providing brokers and property managers a platform to post listings and reach qualified tenants.
MarketplacesPropTechNew York City, US
Lee C. Lin(Founder)Lawrence Zhou(Founder)in
Replicated provides a container-based platform for software vendors to deploy cloud-native applications in customer environments.
Cloud ComputingDeveloper ToolsEnterprise Software
Socure provides an AI-driven platform for digital identity verification, fraud prevention, and risk decisioning, serving enterprises and government agencies across financial services, gaming, healthcare, e-commerce, and other sectors.
AI & Machine LearningCybersecurityFintechNew York, US
John F. Frankel(Director)Sunil Madhu(Executive Officer, Director)Alessandro Piol(Director)Pavlo Protopapa(Director)John Ayers(Executive Officer, Director)
Suplari provides procurement intelligence and AI agents for enterprise procurement teams, helping them consolidate fragmented data and automate decision-making and execution without replacing existing systems.
AI & Machine LearningData & InfrastructureEnterprise SoftwareSeattle, US
Jeff Gerber(Executive Officer, Director, Promoter)inNikesh Parekh(Executive Officer, Director, Promoter)inBrian White(Executive Officer, Promoter)
BoardMatt McIlwain(Director)
Text Blaze is a productivity tool that creates text snippets and templates to reduce repetitive typing across web applications.
Developer ToolsEnterprise SoftwareFuture of WorkSaaSSan Francisco, US
New York, US
Michael Freedman(Executive Officer, Director, Promoter)Peter Fenton(Director)Ajay Kulkarni(Executive Officer, Director, Promoter)Forest Baskett(Director)
BoardSatish Dharmaraj(Director)
Freedom Rave Wear operates a branded resale platform for pre-loved rave fashion, enabling peer-to-peer and off-price sales of both customer items and brand-direct inventory.
Circular EconomyClimate TechDirect to ConsumerE-commerceRetail TechSan Francisco, US
Michael Hodgens(Chief AI Officer)inJacob Disraeli(Executive Officer, Director)Sonia Yang(Executive Officer, Director)
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Frequently asked questions
- What stage does Two Sigma Ventures invest at?
- Two Sigma Ventures invests at the Seed, Series A, Series B stages.
- What is Two Sigma Ventures's typical check size?
- Two Sigma Ventures typically writes checks of $2M – $15M.
- What sectors does Two Sigma Ventures focus on?
- Two Sigma Ventures focuses on Biotech, Consumer, Data & Infrastructure, EdTech, Enterprise Software, Fintech, Hardware, Healthtech, SaaS, Sector Agnostic.
- Where is Two Sigma Ventures located?
- Two Sigma Ventures is headquartered in New York, US.
- Does Two Sigma Ventures lead rounds?
- Yes, Two Sigma Ventures leads investment rounds.
Media · Podcasts & interviews
featuring the teamInvesting in Disruptive Tech for Manufacturing Industry - Colin Beirne, Two Sigma Ventures #shorts
VentureFizz · Colin Beirne
#125 Frances Schwiep | Partner @ Two Sigma Ventures - WIN/WIN: Women in Innovation | Acast
Frances Schwiep · shows.acast.com
From Intern to Insider
Two Sigma
Co-investors · 126
Tiger Global is a research-driven investment firm that partners with innovative, high-quality companies over the long term across various stages of their lifecycle.
Scale Venture Partners is an early-stage investor that partners with AI companies to help them grow from founder-led growth into a scalable go-to-market operation.
Amplify Partners is an early-stage venture firm that has invested in technical founders — engineers, researchers, and scientists — building applications, AI models, developer tools, and infrastructure since 2012.
Andreessen Horowitz's Strategic Partnerships page describes collaborations that connect its portfolio companies with established institutions to help scale and deploy their technology.
Accel is a venture capital firm that partners with exceptional founding teams, positioning itself as a first partner to startups globally.
Techstars is a startup accelerator and early-stage investor that funds ambitious founders and provides capital, mentorship, and access to a global network of investors, operators, and corporate partners.
Index Ventures is a venture capital firm that backs founders across the globe, investing in the people behind ideas from early through later stages.
Alumni Ventures (AV) is a venture firm that gives accredited individual investors access to professionally managed, diversified venture portfolios by co-investing alongside leading lead VC firms. It offers annual funds, syndicate deal-by-deal investing, and various investor clubs.
Redpoint Ventures is a venture capital firm established in 1999 by former partners from leading venture firms, focusing on early-stage technology companies across multiple sectors. The firm leverages its partners' technology investment experience and an extensive network of entrepreneurs and industry contacts to support portfolio company growth.
Founder Collective is an early-stage venture capital firm focused on seed and pre-seed investments across all sectors.
Uncork Capital is a seed-stage venture firm that backs founders at the earliest stage, before their potential is widely recognized.
Notable Capital is an early-stage venture firm that partners closely with founders, providing hands-on operational support through a platform team of experienced operators across hiring, sales, leadership development, storytelling, and engineering.
▶114 more co-investors
BenchmarkFirst Round CapitalSusa VenturesBling CapitalLux CapitalMadrona Venture GroupAfore CapitalPrimary Venture PartnersWork-BenchFikaDesigner FundMPG FundSequoia CapitalGV (Google Ventures)Founders FundKhosla VenturesGreylock PartnersLong Journey VenturesInsight PartnersBoxGroupDCVC (Data Collective)Coatue ManagementTrue VenturesSound VenturesCRV (Charles River Ventures)AtomicoGoat CapitalFirstMarkPartech VenturesFundersClubOak HC/FTFreestyle CapitalInnovation EndeavorsForerunner VenturesCaffeinated CapitalLookout VenturesEmergence Capital PartnersStellar CapitalAdditionSoftBank Vision FundResolute VenturesBowery CapitalSouth Park CommonsF-Prime Capital PartnersElectric CapitalIA VenturesSoma Capital8VCCrosslink CapitalRed Swan VenturesRevolutionTrajectory VenturesFoundry GroupOperator LPFlatiron HealthBase10 PartnersDCM VenturesAccompliceBlockchain CapitalPareto HoldingsHomebrewTribe Capital FirstlookCoinbase VenturesCiti VenturesFuel Venture CapitalAIX VenturesWorklife Ventures23andMeAugust CapitalScribble Ventures468 CapitalICONIQ CapitalARCH Venture PartnersHeavybitBaruch Future Ventures9Yards CapitalFuture Perfect VenturesZ47What If VenturesPresence CapitalRA CapitalConstruct CapitalConvective CapitalRace CapitalOpenView Venture PartnersBootstrapLabsDay One VenturesPortage VenturesAV8 VenturesBasecamp FundThe Column GroupAsset Management VenturesFirsthandVCEight Roads VenturesDigitalis VenturesSignal Peak VenturesA*Brewer Lane VenturesIngeborg InvestmentsEVE AtlasHorizonIndie.vcAudaciousNextech InvestDTCPGood Growth CapitalSTILLMARKUnicorn India VenturesNew Markets Venture PartnersGovtech FundAmerica's Frontier FundBonsal CapitalMetalayerOverwater Ventures Llc
Firms observed investing alongside Two Sigma Ventures, from public investor directories. Shared companies are the overlap with Two Sigma Ventures's recorded portfolio.
Similar investors
OMERS Ventures is the venture capital arm of the OMERS pension plan, investing in early-stage technology founders building solutions across North America and Europe.
SBI Investment Korea is a Korean asset management firm within the SBI Group that operates venture capital and private equity funds, positioning itself as a 'New Industry Creator'.
Good Growth Capital is a venture capital firm based in Charleston, SC, focused on early-stage science and technology startups, often spun out of university research labs.
Alibaba Entrepreneurs Fund is a non-profit organization established by Alibaba Group in 2015 that invests in entrepreneurs and startups based in Hong Kong and Taiwan.
Volcanics Venture invests in companies operating in internet innovation, intelligent technology, and healthcare sectors. The firm provides capital and support services to entrepreneurs in these focus areas.