Two Sigma Ventures

Isabl analyzes complete tumor genomes and transcriptomes to identify cancer-associated mutations and biomarkers for comprehensive cancer diagnosis. The company provides genomic testing services for oncology patients and operates in the precision medicine and cancer diagnostics sector.

BiotechDigital HealthMedical Devices

Isabl develops whole genome and transcriptome sequencing technology for cancer diagnosis, delivering comprehensive genomic profiling and treatment options to physicians and research teams. The company provides rapid cancer diagnostic tests in clinically relevant timeframes to improve outcomes for cancer patients globally.

BiotechDigital HealthHealthtechMedical DevicesNew York City, US

Juan Medina(Founder)inAndrew Kung(Founder)Elli Papaemmanuil(Founder)in

Arda develops therapeutics using single-cell computational biology to target and eliminate pathogenic cells in chronic diseases. The company combines drug development expertise with cellular biology to create new therapeutic approaches.

AI & Machine LearningBiotechMedical DevicesAustin, US

Adam Freund(Founder & Chief Executive Officer)Remi-Martin Laberge(Founder and Chief Technology Officer)

An insurance brokerage offering personalized policy solutions for small businesses across multiple sectors including healthcare providers, attorneys, dentists, and nonprofits.

InsurTech

MonetizeNow provides a unified platform combining configure-price-quote (CPQ), billing, and metering capabilities for SaaS businesses. The platform is designed for SaaS companies to manage subscriptions, consumption-based pricing, and multiple business models through a single product catalog and API-first architecture.

Enterprise SoftwareFintechSaaS

Sandeep(Founder / CEO)

Okteto is a developer platform that enables teams to develop cloud-native applications by moving development and preview environments into the cloud. The company serves software development teams of any size seeking to accelerate their development cycles and innovation.

AI & Machine LearningCloud ComputingData & InfrastructureDeveloper ToolsEnterprise SoftwareSan Francisco, US

Ramiro Berrelleza(Founder)inPablo Chico de Guzman(Founder/CTO)inRamon Lamana(Founder)in

Osmo develops artificial intelligence and computational tools for fragrance creation and ingredient discovery. The company serves perfumers, fragrance houses, and consumer brands by providing an Olfactory Intelligence platform that digitizes and predicts scent from molecular structure.

AI & Machine LearningConsumerDeep TechNew Jersey, US

Alex Wiltschko(Founder and CEO)

Per Diem builds a mobile app builder designed for local restaurant and coffee shop owners to compete with larger chains by turning customers into loyal patrons.

ConsumerEnterprise SoftwareMarketing TechRetail TechSaaSNew York City, US

Tomer Molovinsky(Founder)inDoron Segal(Founder)in

RentHop is an apartment rental marketplace that connects renters with listings ranked by freshness, accuracy, and property manager responsiveness, while providing brokers and property managers a platform to post listings and reach qualified tenants.

MarketplacesPropTechNew York City, US

Lee C. Lin(Founder)Lawrence Zhou(Founder)in

Replicated provides a container-based platform for software vendors to deploy cloud-native applications in customer environments. The platform enables self-hosted software delivery with enhanced security and control.

Cloud ComputingDeveloper ToolsEnterprise Software

GrantMarc

Socure provides an AI-driven platform for digital identity verification, fraud prevention, and risk decisioning, serving enterprises and government agencies across financial services, gaming, healthcare, e-commerce, and other sectors. The platform uses machine learning to achieve high accuracy in identity verification and fraud detection across customer onboarding, authentication, and regulatory compliance workflows.

AI & Machine LearningCybersecurityFintech

Suplari provides procurement intelligence and AI agents for enterprise procurement teams, helping them consolidate fragmented data and automate decision-making and execution without replacing existing systems.

AI & Machine LearningData & InfrastructureEnterprise Software

Text Blaze is a productivity tool that creates text snippets and templates to reduce repetitive typing across web applications. It works as a Chrome extension, macOS app, or Windows app and integrates with Gmail, Google Docs, LinkedIn, Salesforce, and other platforms.

Developer ToolsEnterprise SoftwareFuture of WorkSaaSSan Francisco, US

Dan Barak(Founder)inScott Fortmann-Roe(Founder)in

Freedom Rave Wear operates a branded resale platform for pre-loved rave fashion, enabling peer-to-peer and off-price sales of both customer items and brand-direct inventory. The program supports sustainability and community engagement within the rave wear market.

Circular EconomyClimate TechDirect to ConsumerE-commerceRetail TechSan Francisco, US

Michael Hodgens(Chief AI Officer)in