Two Sigma Ventures
Venture capitalNew York · Seed–Series B · 16 people tracked
Also known as Two Sigma Ventures Maple
Investment thesis
Originating from a quantitative hedge fund, they use quant models and embed data scientists, engineers, and researchers to tackle ML and data-pipeline challenges for AI, software infrastructure, and hardtech.
Source: firm website, verified Aug 3, 2026.
Team · 16 people
from public directories
Founder mafia
2 people who came through Two Sigma Ventures went on to found or lead other companies.
What they invest in
from 40 of 43 portfolio companiesEnterprise Software ×13SaaS ×12AI & Machine Learning ×11Developer Tools ×7Fintech ×7Healthtech ×7Biotech ×6Consumer ×5
HQs:United States×31Canada×1Mexico×1
Investments · 43 tracked
founders shown can be your intro pathBy year:2026 · 52025 · 62024 · 22023 · 32021 · 32019 · 12018 · 12017 · 22015 · 124 dated
EnergySacramento, US
Sunny Trinh(Chief Executive Officer)Chris Merkel(Chief Operating Officer)David Goertz(Chief Financial Officer)
BoardCarl Stanton(Director)Stephen Kukucha(Director)
Board seatWray Thorn· per SEC Form D · $2M raise · filed Dec 2025
EnergyHouston, US
William Dale Dale(Chief Financial Officer)Christopher Cooper(Chief Executive Officer)
BoardCarter McCain(Director)Si-Yeon Kim(Director)Sanford Cockrell(Director)
Board seatWray Thorn· per SEC Form D · $10M raise · filed Feb 2026
Flatfile is an AI-powered data migration platform that lets enterprises collect, map, clean, transform, and validate data from files, APIs, webhooks, databases, and cloud storage.
AI & Machine LearningData & InfrastructureEnterprise SoftwareDenver, US
David Boskovic(Executive Officer, Director)inEric Crane(Executive Officer, Director)AVERY CHASE(Executive Officer, Director)
BoardRORY O'DRISCOLL(Director)FRANCES SCHWEIP(Director)
Co-investorsAfore CapitalScale Venture PartnersTiger Global ManagementWorkday VenturesDesigner FundGradient Ventures
Hyper provides avatar and AI storytelling tools that enable consumers to create their own content and experiences, positioning itself in the creator economy space.
AI & Machine LearningConsumerCreator EconomyMedia & EntertainmentSocialSan Francisco, US
Aaron Ng(Founder/CEO)inLevanJimAndrew Breckenridge(Executive Officer, Director)
Co-investorsY CombinatorMakers Fund
Isabl develops whole genome and transcriptome sequencing technology for cancer diagnosis, delivering comprehensive genomic profiling and treatment options to physicians and research teams.
BiotechDigital HealthHealthtechMedical DevicesNew York City, US
Juan Medina(Founder)inAndrew Kung(Founder)inElli Papaemmanuil(Founder)in
Co-investorsY CombinatorEvolution VC Partners
Isabl develops genomic sequencing technology for cancer diagnosis, enabling whole genome and transcriptome testing in clinically relevant timeframes to provide comprehensive treatment options.
BiotechDigital HealthMedical Devices
Co-investorsBoxOne VenturesY CombinatorEvolution VC Partners
Isabl provides a genomic cancer test that analyzes the entire tumor genome and transcriptome to identify cancer-associated mutations and biomarkers for diagnosis.
BiotechHealthtechMedical Devices
Co-investorsBoxOne Ventures
Freeform develops additive manufacturing (3D printing) technology aimed at bringing this production method to industrial applications across multiple sectors.
Advanced ManufacturingAI & Machine LearningDeep TechHardwareRoboticsHawthorne, US
Thomas J. Ronacher(Executive Officer, Director)Erik Palitsch(CEO)Tasso Lappas(Chief Scientific Officer)
BoardMohammad Islam(Director)Keith Dunleavy(Director)
Board seatDusan Perovic· per SEC Form D
Co-investorsLinse CapitalMVP VenturesThreshold VenturesW ventures10x FoundersFounders Fund+1 more
Gameto develops cell therapy and reproductive technologies to treat infertility and improve women's health outcomes.
BiotechFemTechHealthtechMedical DevicesAustin, US
Dina Turner(Co-founder & Chief Executive Officer)inMartin Varsavsky(Co-founder & Chairman)inDina Radenkovic(Executive Officer, Director)
BoardDylan Morris(Director)Maryanna Saenko(Director)in
Board seatDusan Perovic· per SEC Form D · $44M raise · filed Aug 2025
Co-investorsBold Capital PartnersFuture VenturesIngeborg InvestmentsJazzya InvestmentsKorify CapitalLux Capital+11 more
Odeko provides software and operational systems for independent food service businesses to compete with chain restaurants through cost optimization and margin improvement.
Enterprise SoftwareFoodTechLogistics & Supply ChainRetail TechSaaSNew York City, US
James Burkhardt(Founder)inDane Atkinson(Chief Executive Officer)Tom Hore(Chief Product Officer)Stephen Mar(Chief Legal & Administrative Officer)Todd Sunsted(Executive Officer)Bernar Bekirov(Executive Officer)
Board seatDan Abelon· per SEC Form D · $49.5M raise · filed Jan 2022
Co-investorsB Capital GroupB4 CapitalEmles Venture PartnersMPG FundNotable CapitalPROOF+11 more
WHOOP is a wearable health monitoring device that provides 24/7 tracking of sleep, strain, stress, and heart health metrics to help users optimize their fitness and wellness.
HealthtechWellness & FitnessBoston, US
Will Ahmed(Founder)inWilliam Ahmed(Executive Officer, Director)
BoardJeff Fagnan(Director)
Board seatWray Thorn· per SEC Form D · $30.2M raise · filed Mar 2018
Co-investorsAccompliceBose VenturesCAVU Consumer PartnersCollaborative FundDeviation CapitalDrive by DraftKings+10 more
Newport Beach, US
R. Stephen Hannahs(Executive Officer, Director)Arthur R. Schmidt(Executive Officer)Bryan Billings(Executive Officer)Cesar Romero-Aguilar(Executive Officer)Loren M. Dollet(Executive Officer)J. Chandler Martin(Director)
Board seatWray T. Thorn· per SEC Form D · filed Jun 2019
Amper is a production monitoring and intelligence platform that uses IoT sensors to automatically track machines, operators, and jobs in real time and integrates with ERP and MES systems.
Advanced ManufacturingIoTSaaS
Co-investorsConvergeCorazon CapitalLewis & Clark VenturesSterling Road1517Advancit Capital+4 more
New York City, US
Andrew H. Silverstein(Executive Officer, Director)
Co-investorsAdvancit CapitalTechstarsFoundryHorizons VenturesKiwi Venture Partners
Arda develops therapeutics using single-cell computational biology to target and eliminate pathogenic cells in chronic diseases.
AI & Machine LearningBiotechMedical DevicesAustin, US
Adam Freund(Founder & Chief Executive Officer)Remi-Martin Laberge(Founder and Chief Technology Officer)
BoardVineeta Agarwala(Director)in
Co-investorsage1Andreessen HorowitzStrawberry Creek VenturesAlumni VenturesGaingelsGV (Google Ventures)+3 more
Seattle, US
Xiao Wang(Executive Officer, Director)
BoardAmy McCullough(Director)inGreg Gottesman(Director)inBrad Feld(Director)
Co-investorsFounders' Co-opIndustry VenturesPioneer Square LabsTrilogy Equity Partners
Candu is a no-code UX editor that lets product and growth teams build, launch, and A/B test in-app content such as onboarding flows, banners, and product tours using a drag-and-drop editor and a JavaScript snippet.
Developer ToolsEnterprise SoftwareMarketing TechSaaSLos Altos, US
Jonathan Anderson(Executive Officer, Director)inMichele Riccardo Esposito(Executive Officer, Director)inAnthony Esposito(Executive Officer, Director)Jeffrey L Monda(Executive Officer, Director)Richard Warner(Executive Officer, Director)
BoardGil Dibner(Director)in
Co-investorsAngular VenturesEntrepreneur FirstMaverick SiliconSoftBank Group
Carbon Health operates a chain of clinics offering urgent care, primary care, and chronic condition management, combining technology with in-person care to provide broader access to health services.
Digital HealthHealthtechMedia & Entertainment
Eren Bali(Founder)Greg BurrellTom Berry
Co-investors500 Emerging Europe500 GlobalAkkadian VenturesAnnex InvestmentsBuilders VCDCVC (Data Collective)+13 more
Castor provides an electronic data capture (EDC) platform for clinical trials and real-world evidence studies, combining eCOA/ePRO, eConsent, and clinical data management with AI-based extraction of source data into eCRFs.
AI & Machine LearningHealthtechSaaS
Co-investorsF-Prime CapitalChartered GroupInkef
An insurance brokerage offering personalized policy solutions for small businesses across multiple sectors including healthcare providers, attorneys, dentists, and nonprofits.
InsurTechNew York, US
Inaki Berenguer(Executive Officer, Director)
BoardCharles Moldow(Director)inJohn Buttrick(Director)
Co-investorsFounder CollectiveKibo VenturesKleiner PerkinsR136 VenturesUnion Square Ventures (USV)Foundation Capital+2 more
Hexagon Bio develops novel payload mechanisms for antibody-drug conjugates (ADCs) aimed at overcoming resistance to current cancer treatments and expanding ADC indications.
BiotechDeep TechHealthtechMenlo Park, US
Colin James Bell Harvey(Director)Brian T. Naughton(Director)Maureen E. Hillenmeyer(Executive Officer, Director)Maureen Hillenmeyer(CEO & Co-Founder)in
BoardAlex Kolich(Director)
Co-investorsB3 HoldingNextech InvestSoftBank Vision FundThe Column Group8VCCasdin Capital
Highbeam is a financial technology company (not a bank) offering banking services, credit, spend management, and AI agents that automate finance tasks like treasury, reporting, and scenario analysis.
AI & Machine LearningDirect to ConsumerE-commerceFintechNew York, US
Samir Shergill(Co-founder & CEO)inGautam Gupta(Co-founder)in
BoardJohn Gardner(Director)inAmish Jani(Director)inRishi Garg(Director)
Co-investorsAcrew CapitalFirstMark CapitalMayfield FundVesey Ventures
Membrane Labs provides an institutional infrastructure platform for digital asset credit, unifying counterparty discovery, loan workflows, and collateral management with real-time visibility, automated margin enforcement, and multi-custodian connectivity.
Crypto & Web3Enterprise SoftwareFintech
Carson Cook(Founder)in
Co-investorsArca FundsElectric CapitalFourth Revolution Capital (4RC)Lvna CapitalMarin Digital VenturesPoint72 Ventures+7 more
Membrane builds an AI-powered integration platform that enables software products to automatically connect with and adapt to other applications.
AI & Machine LearningDeveloper ToolsEnterprise SoftwareSaaS
Daniil Bratchenko(Founder)
Co-investorsBrevan Howard DigitalElectric CapitalFlow TradersFramework VenturesJump CryptoPoint72 Ventures+1 more
MonetizeNow provides a unified platform combining configure-price-quote (CPQ), billing, and metering capabilities for SaaS businesses.
Enterprise SoftwareFintechSaaSSanta Clara, US
Sandeep(Founder / CEO)Sandeep Jain(Founder)inJeff Gibson(Founder)
Co-investorsUncork CapitalGTMfundCategory VenturesNext Frontier Capital
Nelo offers a mobile credit app for consumers in Mexico, letting users get approved for credit and pay in biweekly installments.
ConsumerFintechMexico City, MX
Kyle Miller(Founder)inStephen Hebson(Founder)in
Co-investorsEastward Capital PartnersHomebrewTop Corner CapitalGaingelsMoving CapitalSusa Ventures
NetBox Labs offers NetBox, a platform for documenting, modeling, automating, and securing network and data center infrastructure, including IP address management and a source of truth for physical and virtual assets.
Cloud ComputingData & InfrastructureDeveloper ToolsEnterprise SoftwareNew York, US
Bill Lapcevic(Founder)inRaj Dutt(Director)Salil Jani(Executive Officer, Director)Kristopher Beevers(Executive Officer, Director)Xiao Wei(Executive Officer)
BoardGlenn Solomon(Director)
Co-investorsEntrée CapitalFlybridge Capital PartnersFounder CollectiveMango CapitalNGP CapitalNotable Capital+2 more
Okteto is a developer platform that enables teams to develop cloud-native applications by moving development and preview environments into the cloud.
AI & Machine LearningCloud ComputingData & InfrastructureDeveloper ToolsEnterprise SoftwareSaaSSan Francisco, US
Ramiro Berrelleza(Founder)inPablo Chico de Guzman(Founder/CTO)inRamon Lamana(Founder)inRamiro Antonio Berrelleza Perez(Executive Officer, Director, Promoter)
Co-investorsRoot Ventures Manager, LlcY CombinatorHaystackMAGIC Fund
Osmo develops artificial intelligence and computational tools for fragrance creation and ingredient discovery.
AI & Machine LearningConsumerDeep TechNew Jersey, US
Alex Wiltschko(Founder and CEO)inRohinton Mehta(Founder)
Co-investorsLux CapitalAlumni VenturesCollaborative FundDeviation Capital
Per Diem builds a mobile app builder designed for local restaurant and coffee shop owners to compete with larger chains by turning customers into loyal patrons.
ConsumerEnterprise SoftwareMarketing TechRetail TechSaaSNew York City, US
Tomer Molovinsky(Founder)inDoron Segal(Founder)in
Co-investorsY Combinator
Remote helps companies hire, pay, and manage employees internationally by removing barriers to cross-border employment.
Future of WorkHR TechSaaS
Marcelo Lebre(Co-founder & President)inJob van der Voort(Co-founder & CEO)in
Co-investorsAccelB Capital GroupB4 CapitalBase PartnersCategory VenturesDaft Capital+10 more
RentHop is an apartment rental marketplace that connects renters with listings ranked by freshness, accuracy, and property manager responsiveness, while providing brokers and property managers a platform to post listings and reach qualified tenants.
MarketplacesPropTechNew York City, US
Lee C. Lin(Founder)Lawrence Zhou(Founder)inLee Lin(Founder)in
Co-investorsY CombinatorSocial Starts
Replicated provides a container-based platform for software vendors to deploy cloud-native applications in customer environments.
Cloud ComputingDeveloper ToolsEnterprise Software
Co-investorsAmplify Partnersboldstart venturesFounder CollectiveHeavybitMucker CapitalPreston-Werner Ventures+4 more
Socure provides an AI-driven platform for digital identity verification, fraud prevention, and risk decisioning, serving enterprises and government agencies across financial services, gaming, healthcare, e-commerce, and other sectors.
AI & Machine LearningCybersecurityFintechNew York, US
John Ayers(Executive Officer, Director)in
BoardJohn F. Frankel(Director)inSunil Madhu(Executive Officer, Director)inAlessandro Piol(Director)Pavlo Protopapa(Director)Philip Eytan(Director)
Co-investorsAccelAlpha PartnersAltaIR CapitalAmity VenturesCommerce VenturesConnectivity Ventures+15 more
Steadily provides landlord insurance policies that protect rental property owners against property damage, liability claims, and lost rental income.
FintechInsurTechPropTechBeaverton, US
Darren Nix(Executive Officer, Director)David Tulig(Director)inDatha Santomieri(Director)
BoardJake Jolis(Director)
Co-investorsClocktower VenturesMatrixNext Coast VenturesNight CapitalVesta VenturesZigg Capital+2 more
Suplari provides procurement intelligence and AI agents for enterprise procurement teams, helping them consolidate fragmented data and automate decision-making and execution without replacing existing systems.
AI & Machine LearningData & InfrastructureEnterprise SoftwareSeattle, US
Jeff Gerber(Executive Officer, Director, Promoter)inNikesh Parekh(Executive Officer, Director, Promoter)inBrian White(Executive Officer, Promoter)Mark Jancola(Founder)in
BoardMatt McIlwain(Director)
Co-investorsAmplify PartnersMadrona Venture GroupWorkday VenturesShasta Ventures
Swarm builds uncrewed aerial vehicles (UAVs) designed for swarming, combining on-aircraft autonomy, sensor mesh, and edge compute so small teams can coordinate thousands of air, sea, and ground assets in contested, communications-limited environments.
Defense TechHardwareRobotics
Danny Goodman(Executive Chairman)inOliver Palmer(CRO)inPeter Kalogiannis(CEO)in
Co-investorsCoatue ManagementConstruct CapitalHumba VenturesMaC Venture CapitalAlumni VenturesChampion Hill Ventures+6 more
Text Blaze is a productivity tool that creates text snippets and templates to reduce repetitive typing across web applications.
Developer ToolsEnterprise SoftwareFuture of WorkSaaSSan Francisco, US
Dan Barak(Founder)inScott Fortmann-Roe(Founder)inDan B(Founder)in
Co-investorsFourth RealmY CombinatorSusa Ventures
PostgreSQL database company behind TimescaleDB, Tiger Cloud and a Postgres search stack for high-ingest time series, operational analytics, machine/physical-world data and AI retrieval workloads.
Developer ToolsEnterprise SoftwareNew York, US
Ajay Kulkarni(Co-founder and Chief Executive Officer)Michael J. Freedman(Co-founder and Chief Technology Officer)Rahil Sondhi(Founder of acquired PopSQL; joined Timescale in 2024)Kerri Damm(Chief Financial Officer)Ramon Guiu(Vice President, Product)Jose Sahad(Vice President, Engineering)
Co-investorsBenchmarkIcon VenturesNew Enterprise Associates (NEA)Redpoint VenturesTiger Global Management
Tive provides visibility solutions for supply chain and shipment operations, helping stakeholders track and manage shipments to ensure on-time and complete delivery.
IoTLogistics & Supply ChainBoston, US
Krenar Komoni(Founder & CEO)in
Co-investorsBaukunstBroom VenturesBVVCFloating PointOne Way VenturesQualcomm Ventures+10 more
Tive makes NFC-enabled temperature loggers for monitoring temperature-sensitive shipments across the cold chain, including direct-to-consumer deliveries.
HardwareIoTLogistics & Supply ChainSaaS
Co-investorsNextView VenturesAXA Venture PartnersFifth WallHyperplane Venture CapitalQualcomm VenturesRRE Ventures+3 more
Freedom Rave Wear operates a branded resale platform for pre-loved rave fashion, enabling peer-to-peer and off-price sales of both customer items and brand-direct inventory.
Circular EconomyClimate TechDirect to ConsumerE-commerceRetail TechSan Francisco, US
Jacob Disraeli(Executive Officer, Director)Jake Disraeli(Founder)inMichael Hodgens(Chief AI Officer)inSonia Yang(Executive Officer, Director)
Co-investorsAlante CapitalBAM VenturesBling CapitalGreen Meadow VenturesInterlace VenturesTechstars+2 more
Wealthsimple is a Canadian financial services company offering investing, stock and crypto trading, saving and spending accounts, and tax filing through a simplified consumer platform.
ConsumerCrypto & Web3FintechSaaSToronto, CA
Michael Katchen(Co-founder & CEO)inBrett Huneycutt(Co-founder & CPO)inRudy Adler(Co-founder (formerly CMO))Radhika Kakkar(Chief Operating Officer)Diederik van Liere(Chief Technology Officer)Leen Li(Former CFO; CEO, Wealthsimple Foundation)
Co-investorsAlkeon InnovationAllianz XDiagramDragoneer Investment GroupDST GlobalGIC+12 more
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Exits · 3
IPOs and acquisitions across the tracked portfolioDevvStreamOTC: DEVSFXCF GlobalNASDAQ: SAFXCoverWalletacq. by Aon
Portfolio news
latest coverage across their companiesWealthsimple · investmentexecutive.com · Aug 21, 2026
Swarm Aero · defence-blog.com · Aug 11, 2026
Remote · defensedaily.com · Aug 3, 2026
Gameto · smartcompany.com.au · Jul 17, 2026
Per Diem · bpfund.com · Jul 10, 2026
Steadily · steadily.com · Jun 28, 2026
Candu · theglobeandmail.com · Jun 23, 2026
DevvStream · intellectia.ai · May 30, 2026
Frequently asked questions
- What stage does Two Sigma Ventures invest at?
- Two Sigma Ventures invests at the Seed, Series A, Series B stages.
- What is Two Sigma Ventures's typical check size?
- Two Sigma Ventures typically writes checks of $2M – $15M.
- What sectors does Two Sigma Ventures focus on?
- Two Sigma Ventures focuses on Biotech, Consumer, Data & Infrastructure, EdTech, Enterprise Software, Fintech, Hardware, Healthtech, SaaS, Sector Agnostic.
- Where is Two Sigma Ventures located?
- Two Sigma Ventures is headquartered in New York, US.
- Does Two Sigma Ventures lead rounds?
- Yes, Two Sigma Ventures leads investment rounds.
- Who does Two Sigma Ventures co-invest with?
- Two Sigma Ventures most often shares deals with DST Global, Greylock Partners, ICONIQ, among 16 tracked co-investors.
Media · Podcasts & interviews
featuring the teamInvesting in Disruptive Tech for Manufacturing Industry - Colin Beirne, Two Sigma Ventures #shorts
VentureFizz · Colin Beirne
#125 Frances Schwiep | Partner @ Two Sigma Ventures - WIN/WIN: Women in Innovation | Acast
Frances Schwiep · shows.acast.com
The People of Two Sigma | Jin, Quantitative Researcher
Two Sigma
From Intern to Insider
Two Sigma
Co-investors · 127
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Accel is a venture capital firm that partners with exceptional teams, positioning itself as a first partner to founders globally.
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Redpoint Ventures is a venture capital firm established in 1999 by former partners from leading venture firms, focusing on early-stage technology companies across multiple sectors. The firm leverages its partners' technology investment experience and an extensive network of entrepreneurs and industry contacts to support portfolio company growth.
▶115 more co-investors
Notable CapitalFirst Round CapitalSusa VenturesScale Venture PartnersAmplify PartnersHomebrewScribble VenturesInkefAndreessen HorowitzGV (Google Ventures)Khosla VenturesGreylock PartnersUncork CapitalBenchmarkDCVC (Data Collective)Coatue ManagementGradient VenturesFirstMark CapitalBling CapitalMadrona Venture GroupAfore CapitalResolute VenturesF-Prime CapitalElectric Capital8VCAccomplicePrimary Venture PartnersICONIQ CapitalWork-BenchHeavybitFika9Yards CapitalRA CapitalConstruct CapitalDay One VenturesThe Column GroupIngeborg InvestmentsDesigner FundNextech InvestMPG FundOverwater Ventures LlcLong Journey VenturesInsight PartnersBoxGroupTrue VenturesSound VenturesCRV (Charles River Ventures)AtomicoGoat CapitalPartech VenturesFundersClubOak HC/FTFreestyle CapitalInnovation EndeavorsForerunner VenturesCaffeinated CapitalLookout VenturesEmergence Capital PartnersStellar CapitalAdditionBowery CapitalSouth Park CommonsIA VenturesSoma CapitalCrosslink CapitalRed Swan VenturesRevolutionTrajectory VenturesOperator LPBase10 PartnersDCM VenturesBlockchain CapitalPareto HoldingsTribe Capital FirstlookCoinbase VenturesCiti VenturesFuel CapitalAIX VenturesWorklife Ventures23andMeAugust Capital468 CapitalARCH Venture PartnersBaruch Future VenturesFuture Perfect VenturesZ47What If VenturesPresence CapitalConvective CapitalRace CapitalOpenView Venture PartnersBootstrapLabsPortage VenturesAV8 VenturesBasecamp FundAsset Management VenturesFirsthandVCEight Roads VenturesDigitalis VenturesSignal Peak VenturesA*Brewer Lane VenturesEVE AtlasHorizonIndie.vcAudaciousDTCPGood Growth CapitalSTILLMARKUnicorn India VenturesNew Markets Venture PartnersGovtech FundAmerica's Frontier FundBonsal CapitalMetalayer
Firms observed investing alongside Two Sigma Ventures, from public investor directories. Shared companies are the overlap with Two Sigma Ventures's recorded portfolio.
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