Two Sigma Ventures
Venture capitalNew York · Seed–Series B · 25 people tracked
Also known as Two Sigma Ventures Maple
Find your way into Two Sigma Ventures
1,868 people in our graph share verified history with the Two Sigma Ventures team — schools, employers, funds. One of them is your warm intro.
Investment thesis
Originating from a quantitative hedge fund, they use quant models and embed data scientists, engineers, and researchers to tackle ML and data-pipeline challenges for AI, software infrastructure, and hardtech.
Source: firm website, verified Aug 3, 2026.
Team · 25 people
from public directories
Founder mafia
4 people who came through Two Sigma Ventures went on to found or lead other companies.
What they invest in
from 55 of 69 portfolio companiesAI & Machine Learning ×21Enterprise Software ×19SaaS ×15Developer Tools ×10Fintech ×9Healthtech ×9Biotech ×8Data & Infrastructure ×8
HQs:United States×46Canada×1Finland×1Mexico×1Netherlands×1
Investments · 69 tracked
founders shown can be your intro pathBy year:2026 · 82025 · 62024 · 52023 · 72022 · 42021 · 102020 · 42019 · 22018 · 62017 · 22015 · 12014 · 156 dated
DevvStream develops and manages technology-based sustainability projects that generate environmental assets such as carbon credits and renewable energy certificates for corporations and governments seeking to offset emissions.
EnergySacramento, US
Sunny Trinh(Chief Executive Officer)inChris Merkel(Chief Operating Officer)inDavid Goertz(Chief Financial Officer)
BoardCarl Stanton(Director)Stephen Kukucha(Director)
Board seatWray Thorn· per SEC Form D · $2M raise · filed Dec 2025
XCF is a publicly traded renewable fuels company that produces sustainable aviation fuel and renewable diesel from low-carbon feedstocks such as waste oils, agricultural residues, and distillers corn oil.
CleantechClimate TechEnergyHouston, US
William Dale Dale(Chief Financial Officer)Christopher Cooper(Chief Executive Officer)
BoardCarter McCain(Director)Si-Yeon Kim(Director)Sanford Cockrell(Director)
Board seatWray Thorn· per SEC Form D · $10M raise · filed Feb 2026
Flatfile is an AI-powered data migration platform that lets enterprises collect, map, clean, transform, and validate data from files, APIs, webhooks, databases, and cloud storage.
AI & Machine LearningData & InfrastructureEnterprise SoftwareDenver, US
David Boskovic(Executive Officer, Director)inEric Crane(Executive Officer, Director)AVERY CHASE(Executive Officer, Director)
BoardRORY O'DRISCOLL(Director)inFRANCES SCHWEIP(Director)
Co-investorsAfore CapitalScale Venture PartnersTiger Global ManagementWorkday VenturesDesigner FundGradient Ventures+1 more
.jpeg){kind=logo}
Flatfile provides a platform that automates data onboarding by mapping, transforming, and validating raw customer data with AI assistance.
AI & Machine LearningData & InfrastructureDeveloper ToolsEnterprise SoftwareSaaS
David Boskovic(Co-founder)Eric Crane(Co-founder)
Co-investorsAfore CapitalGradient VenturesScale Venture PartnersTiger Global ManagementWorkday VenturesEssence Venture Capital
Hyper provides avatar and AI storytelling tools that enable consumers to create their own content and experiences, positioning itself in the creator economy space.
AI & Machine LearningConsumerCreator EconomyMedia & EntertainmentSocialSan Francisco, US
Aaron Ng(Founder/CEO)inLevanJimAndrew Breckenridge(Executive Officer, Director)
Co-investorsY CombinatorMakers Fund
Isabl develops whole genome and transcriptome sequencing technology for cancer diagnosis, delivering comprehensive genomic profiling and treatment options to physicians and research teams.
BiotechDigital HealthHealthtechMedical DevicesNew York City, US
Juan Medina(Founder)inAndrew Kung(Founder)inElli Papaemmanuil(Founder)in
Co-investorsY CombinatorBoxOne VenturesEvolution VC PartnersSand Hill Angels
Tive provides real-time location and condition tracking for shipments, helping supply chain teams monitor temperature, humidity, light, and shock throughout transit.
AI & Machine LearningEdTechIoTLogistics & Supply ChainSector AgnosticSiberia, US
Semyon DukachinIvan Crewkov(CEO and co-founder)Krenar Komoni
Co-investorsBITKRAFT VenturesEducapitalFifth WallGoodwater CapitalPoint72 VenturesQualcomm Ventures+7 more
Freeform develops additive manufacturing (3D printing) technology aimed at bringing this production method to industrial applications across multiple sectors.
Advanced ManufacturingAI & Machine LearningDeep TechHardwareRoboticsHawthorne, US
Thomas J. Ronacher(Executive Officer, Director)inErik Palitsch(CEO)inTasso Lappas(Chief Scientific Officer)in
BoardMohammad Islam(Director)Keith Dunleavy(Director)
Board seatDusan Perovic· per SEC Form D
Co-investorsLinse CapitalMVP VenturesThreshold VenturesW ventures10x FoundersFounders Fund+1 more
Gameto develops cell therapy and reproductive technologies to treat infertility and improve women's health outcomes.
BiotechFemTechHealthtechMedical DevicesAustin, US
Dina Turner(Co-founder & Chief Executive Officer)inMartin Varsavsky(Co-founder & Chairman)inDina Radenkovic(Executive Officer, Director)in
BoardDylan Morris(Director)inMaryanna Saenko(Director)in
Board seatDusan Perovic· per SEC Form D
Co-investorsBold Capital PartnersFuture VenturesIngeborg InvestmentsJazzya InvestmentsKorify CapitalLux Capital+13 more
Odeko provides software and operational systems for independent food service businesses to compete with chain restaurants through cost optimization and margin improvement.
Enterprise SoftwareFoodTechLogistics & Supply ChainRetail TechSaaSNew York City, US
James Burkhardt(Founder)inDane Atkinson(Chief Executive Officer)inTom Hore(Chief Product Officer)inStephen Mar(Chief Legal & Administrative Officer)inTodd Sunsted(Executive Officer)Bernar Bekirov(Executive Officer)in
Board seatDan Abelon· per SEC Form D
Co-investorsB Capital GroupB4 CapitalEmles Venture PartnersMPG FundNotable CapitalPROOF+11 more
.jpeg){kind=logo}
WHOOP is a wearable health monitoring device that provides 24/7 tracking of sleep, strain, stress, and heart health metrics to help users optimize their fitness and wellness.
HealthtechWellness & FitnessBoston, US
Will Ahmed(Founder)in
BoardJeff Fagnan(Director)
Board seatWray Thorn· per SEC Form D · $30.2M raise · filed Mar 2018
Co-investorsAccompliceBose VenturesCAVU Consumer PartnersCollaborative FundDeviation CapitalDrive by DraftKings+10 more
Amper is a production monitoring and intelligence platform that uses IoT sensors to track machines, operators, and jobs in real time, helping manufacturers identify hidden capacity and reduce downtime.
Advanced ManufacturingIoTSaaS
Akshat Thirani(Founder & CEO)in
Co-investorsConvergeCorazon CapitalLewis & Clark VenturesSterling Road1517Advancit Capital+4 more
New York City, US
Andrew H. Silverstein(Executive Officer, Director)in
Co-investorsAdvancit CapitalTechstarsFoundryHorizons VenturesKiwi Venture Partners
Arda develops therapeutics using single-cell computational biology to target and eliminate pathogenic cells in chronic diseases.
AI & Machine LearningBiotechMedical DevicesAustin, US
Adam Freund(Founder & Chief Executive Officer)inRemi-Martin Laberge(Founder and Chief Technology Officer)in
BoardVineeta Agarwala(Director)in
Co-investorsage1Andreessen HorowitzStrawberry Creek VenturesAlumni VenturesGaingelsGV (Google Ventures)+3 more
__Twitter.png)
Arda Therapeutics is a drug development company that uses single-cell computational biology to identify and eliminate pathogenic cells as a way to treat chronic diseases.
AI & Machine LearningBiotechDigital HealthLongevityMedical Devices
Adam Freund(Founder & Chief Executive Officer)inRemi-Martin Laberge(Founder & Chief Technology Officer)in
Co-investorsGV (Google Ventures)Alumni VenturesAxial VCGaingelsIndicator VenturesMana Ventures+1 more
Artemis is an AI-native security operations platform that builds a live model of an organization's environment across identity, cloud, endpoint, and SaaS to detect, investigate, and respond to attacks autonomously.
AI & Machine LearningCybersecurityEnterprise Software
Co-investorsBrightmindFirst Round CapitalTheory VenturesFelicis Ventures
Candu is a no-code UX editor that lets product and growth teams build, launch, and A/B test in-app content such as onboarding flows, banners, and product tours using a drag-and-drop editor and a JavaScript snippet.
Developer ToolsEnterprise SoftwareMarketing TechSaaSLos Altos, US
Jonathan Anderson(Executive Officer, Director)inMichele Riccardo Esposito(Executive Officer, Director)inAnthony Esposito(Executive Officer, Director)Jeffrey L Monda(Executive Officer, Director)Richard Warner(Executive Officer, Director)
BoardGil Dibner(Director)in
Co-investorsAngular VenturesEntrepreneur FirstMaverick SiliconSoftBank Group
Carbon Health operates a chain of clinics offering urgent care, primary care, and chronic condition management, combining technology with in-person care to provide broader access to health services.
Digital HealthHealthtechMedia & Entertainment
Eren Bali(Founder)inGreg BurrellinTom Berry
Co-investors500 Emerging Europe500 GlobalAkkadian VenturesAnnex InvestmentsBuilders VCCatalio Capital Management, LP+17 more
Castor provides a clinical trial data platform that combines electronic data capture, AI-assisted source data extraction with human review, and real-world evidence collection for medical device manufacturers, biopharma, diagnostics, and academic research teams.
AI & Machine LearningCloud ComputingData & InfrastructureDigital HealthHealthtechMedical DevicesSaaSAmsterdam, NL
Co-investorsF-Prime CapitalChartered GroupInkef
Cosmos Innovation develops a machine learning platform for optimizing recipe development in semiconductor and solar process engineering.
AI & Machine LearningDeep TechSemiconductors
Vijay Chandrasekhar(Founder)inJoel Li(Founder)in
Co-investorsXoraAIX VenturesInnovation EndeavorsTemasekXora Innovation Pte Ltd
An insurance brokerage offering personalized policy solutions for small businesses across multiple sectors including healthcare providers, attorneys, dentists, and nonprofits.
InsurTechNew York, US
Inaki Berenguer(Executive Officer, Director)in
BoardCharles Moldow(Director)inJohn Buttrick(Director)
Co-investorsFounder CollectiveKibo VenturesKleiner PerkinsR136 VenturesUnion Square Ventures (USV)Foundation Capital+2 more
Facet offers flat-fee financial planning memberships that pair members with CFP professionals for a personalized financial roadmap covering investing, tax planning and filing, retirement, estate, insurance, education, and equity compensation.
ConsumerFintechSaaS
Anders Jones(Founder)inPatrick McKenna(Founder)in
Co-investorsWarburg PincusAccelBasis Set VenturesDurable Capital PartnersGreen Cow Venture CapitalMultiplier Capital+3 more
Facet provides personal financial planning and investment management, using diversified low-cost, tax-efficient ETF portfolios paired with a dedicated CFP professional.
ConsumerFintechBaltimore, US
ANDERSON JONES(Executive Officer, Director, Promoter)PAUL MARTIN(Executive Officer)inSHRUTI JOSHI(Executive Officer)inDARSHAN PATEL(Executive Officer)inCHRIS HUFMAN(Executive Officer)inLISA RAPUANO(Executive Officer)
Co-investorsAccelerator VenturesMultiplier CapitalAccelBasis Set VenturesDurable Capital PartnersGreen Cow Venture Capital+4 more
Hexagon Bio develops novel payload mechanisms for antibody-drug conjugates (ADCs) aimed at overcoming resistance to current cancer treatments and expanding ADC indications.
BiotechDeep TechHealthtechMenlo Park, US
Colin James Bell Harvey(Director)Brian T. Naughton(Director)inMaureen E. Hillenmeyer(Executive Officer, Director)inMaureen Hillenmeyer(CEO & Co-Founder)in
BoardAlex Kolich(Director)
Co-investorsB3 HoldingNextech InvestSoftBank Vision FundThe Column Group8VCCasdin Capital
Highbeam is a financial technology company (not a bank) offering banking services, credit, spend management, and AI agents that automate finance tasks like treasury, reporting, and scenario analysis.
AI & Machine LearningDirect to ConsumerE-commerceFintechNew York, US
Samir Shergill(Co-founder & CEO)inGautam Gupta(Co-founder)in
BoardJohn Gardner(Director)inAmish Jani(Director)inRishi Garg(Director)
Co-investorsAcrew CapitalFirstMark CapitalMayfield FundVesey Ventures
Analytics and forecasting solutions for revenue teams.
Boston, US
Frederick Shilmover(Executive Officer, Director)Courtland Cunningham(Director)
BoardJeff Fagnan(Director)
Co-investorsTola CapitalAccompliceDraper Fisher Jurvetson (DFJ)NextView Ventures
Kallyope is a biotechnology company founded by neuroscientists that discovers and develops novel therapeutics targeting neural networks, with a lead candidate in pivotal studies for acute migraine treatment and metabolism programs approaching clinical studies.
BiotechHealthtechNew York City, US
Tom Maniatis(Director)Nancy Thornberry(Executive Officer, Director)inKenneth Clark(Executive Officer)
BoardTerry McGuire(Director)inJoshua Wolfe(Director)inTim Kutzkey(Director)in
Co-investorsDns CapitalIllumina VenturesLux CapitalThe Column GroupPolaris Partners
Membrane Labs provides an institutional infrastructure platform for digital asset credit, unifying counterparty discovery, loan workflows, and collateral management with real-time visibility, automated margin enforcement, and multi-custodian connectivity.
Crypto & Web3Enterprise SoftwareFintech
Carson Cook(Founder)in
Co-investorsArca FundsElectric CapitalFourth Revolution Capital (4RC)Lvna CapitalMarin Digital VenturesPoint72 Ventures+7 more
Mio provides interoperability across collaboration platforms, enabling users to send messages, manage identities, share files, and initiate meetings across different systems.
Developer ToolsEnterprise SoftwareSaaSAustin, US
Tom Hadfield(Founder/CEO)inJames Cundle(Founder/CTO)in
Co-investorsCisco InvestmentsEniac VenturesNewtown PartnersY CombinatorCapital FactoryGoldcrest Capital+6 more
.jpeg){kind=logo}
MonetizeNow provides a unified platform combining configure-price-quote (CPQ), billing, and metering capabilities for SaaS businesses.
Enterprise SoftwareFintechSaaSSanta Clara, US
Sandeep Jain(Founder)inJeff Gibson(Founder)in
Co-investorsUncork CapitalGTMfundCategory VenturesNext Frontier Capital
Nelo offers a mobile credit app for consumers in Mexico, letting users get approved for credit and pay in biweekly installments.
ConsumerFintechMexico City, MX
Kyle Miller(Founder)inStephen Hebson(Founder)in
Co-investorsEastward Capital PartnersHomebrewTop Corner CapitalGaingelsMoving CapitalRogue Capital+2 more
NetBox Labs offers NetBox, a platform for documenting, modeling, automating, and securing network and data center infrastructure, including IP address management and a source of truth for physical and virtual assets.
Cloud ComputingData & InfrastructureDeveloper ToolsEnterprise SoftwareNew York, US
Bill Lapcevic(Founder)inKristopher Beevers(Executive Officer, Director)Salil Jani(Executive Officer, Director)inXiao Wei(Executive Officer)in
BoardRaj Dutt(Director)Glenn Solomon(Director)in
Co-investorsEntrée CapitalFlybridge Capital PartnersFounder CollectiveMango CapitalNGP CapitalNotable Capital+2 more
NewtonX runs a B2B market research platform that combines AI with a network of vetted experts to recruit participants, collect survey and interview data, and deliver automated analysis.
AI & Machine LearningData & InfrastructureEnterprise SoftwareMarketing TechNew York, US
Sascha Eder(Founder & CEO)Jeremy Wood(Co-founder)inSascha Hoffman(Founder & CEO)Germain Chastel(Executive Officer, Director, Promoter)Rebecca Minguela(Director)
BoardWes Barton(Director)in
Co-investorsSprint VcStory VenturesThird PrimeXfund
Obvious is an AI agent platform that collaborates with users to generate work artifacts and complete tasks.
AI & Machine LearningEnterprise SoftwareSaaS
David Boskovic(Founder)in
Co-investorsFounder CollectiveDesigner FundGradient VenturesInsight Partners
Okteto is a developer platform that enables teams to develop cloud-native applications by moving development and preview environments into the cloud.
AI & Machine LearningCloud ComputingData & InfrastructureDeveloper ToolsEnterprise SoftwareSaaSSan Francisco, US
Ramiro Berrelleza(CEO & Co-founder)inPablo Chico de Guzman(CTO & Co-founder)inRamon Lamana(CPO & Co-founder)inRamiro Antonio Berrelleza Perez(Executive Officer, Director, Promoter)
Co-investorsMAGIC FundRoot Ventures Manager, LlcY CombinatorHaystackRoot VenturesUncorrelated Ventures+1 more
Osmo develops artificial intelligence and computational tools for fragrance creation and ingredient discovery.
AI & Machine LearningConsumerDeep TechNew Jersey, US
Alex Wiltschko(Founder and CEO)inRohinton Mehta(Founder)in
Co-investorsLux CapitalAlumni VenturesCollaborative FundDeviation Capital
Per Diem builds a mobile app builder designed for local restaurant and coffee shop owners to compete with larger chains by turning customers into loyal patrons.
ConsumerEnterprise SoftwareMarketing TechRetail TechSaaSNew York City, US
Tomer Molovinsky(Co-founder & CEO)inDoron Segal(Co-founder & CTO)in
Co-investorsY Combinator
Pryon builds tools for enterprise customers to create and deploy agents powered by OpenAI's language models, focusing on the underlying components and architecture rather than simple assembly-line approaches.
AI & Machine LearningDeveloper ToolsEnterprise SoftwareRaleigh, US
Igor Jablokov(Executive Officer, Director)JD Vance(Director)
Co-investorsGreycroftTech Square VenturesAperture Venture CapitalBootstrapLabsBreyer CapitalDuke Capital Partners+3 more
Raincoat develops climate insurance solutions that interconnect insurance providers, reinsurers, distributors, and end-users by using real-time environmental data and sophisticated models.
AI & Machine LearningClimate TechInsurTech
Co-investorsAnthemis VentureMundi VenturesOpen Opportunity FundR/GA Ventures
Remote helps companies hire, pay, and manage employees internationally by removing barriers to cross-border employment.
Future of WorkHR TechSaaS
Marcelo Lebre(Co-founder & President)inJob van der Voort(Co-founder & CEO)in
Co-investorsAccelB Capital GroupB4 CapitalBase PartnersCategory VenturesDaft Capital+11 more
RentHop is an apartment rental marketplace that connects renters with listings ranked by freshness, accuracy, and property manager responsiveness, while providing brokers and property managers a platform to post listings and reach qualified tenants.
MarketplacesPropTechNew York City, US
Lawrence Zhou(Founder)inLee Lin(Founder)in
Co-investorsY CombinatorSocial Starts
Replicated provides a container-based platform for software vendors to deploy cloud-native applications in customer environments.
Cloud ComputingDeveloper ToolsEnterprise Software
Co-investorsAmplify Partnersboldstart venturesFounder CollectiveHeavybitMucker CapitalPreston-Werner Ventures+4 more
.jpeg)
Rive is a design and animation platform where creators build interactive experiences that run natively across web, mobile apps, games, and devices using an open-source runtime and GPU-accelerated vector graphics engine.
Creator EconomyDeveloper Tools
Guido Rosso(Founder)inCraig Sartor(Founder)in
Co-investorsAbstract VenturesAndreessen HorowitzBMW i VenturesCategory VenturesUnusual VenturesWorklife Ventures
Socure provides an AI-driven platform for digital identity verification, fraud prevention, and risk decisioning, serving enterprises and government agencies across financial services, gaming, healthcare, e-commerce, and other sectors.
AI & Machine LearningCybersecurityFintechNew York, US
John Ayers(Executive Officer, Director)in
BoardJohn F. Frankel(Director)inSunil Madhu(Executive Officer, Director)inAlessandro Piol(Director)Pavlo Protopapa(Director)Philip Eytan(Director)
Co-investorsAccelAlpha PartnersAltaIR CapitalAmity VenturesCommerce VenturesConnectivity Ventures+17 more
Steadily provides landlord insurance policies that protect rental property owners against property damage, liability claims, and lost rental income.
FintechInsurTechPropTechBeaverton, US
Darren Nix(Executive Officer, Director)inDavid Tulig(Director)inDatha Santomieri(Director)in
BoardJake Jolis(Director)
Co-investorsClocktower VenturesMatrixNext Coast VenturesNight CapitalNine Four VenturesVesta Ventures+2 more
Suplari provides procurement intelligence and AI agents for enterprise procurement teams, helping them consolidate fragmented data and automate decision-making and execution without replacing existing systems.
AI & Machine LearningData & InfrastructureEnterprise SoftwareSeattle, US
Jeff Gerber(Executive Officer, Director, Promoter)inNikesh Parekh(Executive Officer, Director, Promoter)inBrian White(Executive Officer, Promoter)inMark Jancola(Founder)in
BoardMatt McIlwain(Director)
Co-investorsAmplify PartnersMadrona Venture GroupWorkday VenturesShasta Ventures
SWARM is a decision intelligence platform that helps agrifood and manufacturing organizations solve operational challenges by defining problems clearly before deploying agentic AI and optimization algorithms.
Advanced ManufacturingAgTechAI & Machine LearningData & InfrastructureEnterprise Software
Co-investorsS2G InvestmentsMiddleland CapitalVTC VenturesAlumni VenturesChampion Hill VenturesCoatue Management+12 more
Swarm builds uncrewed aerial vehicles (UAVs) designed for swarming, combining on-aircraft autonomy, sensor mesh, and edge compute so small teams can coordinate thousands of air, sea, and ground assets in contested, communications-limited environments.
Defense TechHardwareRobotics
Danny Goodman(Executive Chairman)inOliver Palmer(CRO)inPeter Kalogiannis(CEO)in
Co-investorsCoatue ManagementConstruct CapitalHumba VenturesMaC Venture CapitalAlumni VenturesChampion Hill Ventures+8 more
.jpeg){kind=logo}
Terray is a drug discovery company that combines proprietary hardware, large-scale experimental datasets, and AI through its EMMI platform to design small molecule medicines.
AI & Machine LearningBiotechDeep Tech
Eli Berlin(Founder)in
BoardChris PicardoinDusan PerovicinSid ShenaiinSamuel BjorkinBassil Dahiyat, Ph.D.
Co-investorsDeviation CapitalDigitalis VenturesMadrona Venture GroupSummit Peak InvestmentsKdT VenturesMana Ventures+3 more
Text Blaze is a productivity tool that creates text snippets and templates to reduce repetitive typing across web applications.
Developer ToolsEnterprise SoftwareFuture of WorkSaaSSan Francisco, US
Dan Barak(Founder)inScott Fortmann-Roe(Founder)inDan B(Founder)in
Co-investorsFourth RealmY CombinatorSusa Ventures
PostgreSQL database company behind TimescaleDB, Tiger Cloud and a Postgres search stack for high-ingest time series, operational analytics, machine/physical-world data and AI retrieval workloads.
Developer ToolsEnterprise SoftwareNew York, US
Ajay Kulkarni(Co-founder and Chief Executive Officer)inMichael J. Freedman(Co-founder and Chief Technology Officer)inRahil Sondhi(Founder of acquired PopSQL; joined Timescale in 2024)inKerri Damm(Chief Financial Officer)inRamon Guiu(Vice President, Product)inJose Sahad(Vice President, Engineering)in
Co-investorsBenchmarkIcon VenturesNew Enterprise Associates (NEA)Redpoint VenturesTiger Global Management
Tive provides visibility solutions for supply chain and shipment operations, helping stakeholders track and manage shipments to ensure on-time and complete delivery.
IoTLogistics & Supply ChainBoston, US
Krenar Komoni(CEO & founder)in
Co-investorsBaukunstBroom VenturesBVVCFloating PointHyperplane Venture CapitalOne Way Ventures+12 more
Tive makes NFC-enabled temperature loggers for monitoring temperature-sensitive shipments across the cold chain, including direct-to-consumer deliveries.
HardwareIoTLogistics & Supply ChainSaaS
Krenar Komoni(Founder & CEO)in
Co-investorsNextView VenturesAXA Venture PartnersBroom VenturesFifth WallHyperplane Venture CapitalQualcomm Ventures+5 more
Freedom Rave Wear operates a branded resale platform for pre-loved rave fashion, enabling peer-to-peer and off-price sales of both customer items and brand-direct inventory.
Circular EconomyClimate TechDirect to ConsumerE-commerceRetail TechSan Francisco, US
Jacob Disraeli(Executive Officer, Director)Jake Disraeli(Founder)inMichael Hodgens(Chief AI Officer)inSonia Yang(Executive Officer, Director)
Co-investorsAlante CapitalBAM VenturesBBG VenturesBling CapitalGreen Meadow VenturesInterlace Ventures+4 more
Treet offers a web and mobile platform for remotely using pharmacy services, letting users order products and consult with pharmacists for same-day delivery within hours.
Digital HealthE-commerceHealthtech
Co-investorsNostetta VenturesAlante CapitalBAM VenturesBBG VenturesBling CapitalFirst Round Capital+4 more
Wealthsimple is a Canadian financial services company offering investing, stock and crypto trading, saving and spending accounts, and tax filing through a simplified consumer platform.
ConsumerCrypto & Web3FintechSaaSToronto, CA
Michael Katchen(Co-founder & CEO)inBrett Huneycutt(Co-founder & CPO)inRudy Adler(Co-founder (formerly CMO))inRadhika Kakkar(Chief Operating Officer)inDiederik van Liere(Chief Technology Officer)inLeen Li(Former CFO; CEO, Wealthsimple Foundation)in
Co-investorsAlkeon InnovationAllianz XDiagramDragoneer Investment GroupDST GlobalGIC+15 more
Engineers microbes that make useful molecules for everyday materials (acquired by Ginkgo Bioworks).
Emeryville, US
Erik (Jed) Dean(Executive Officer)Zachariah Serber(Executive Officer, Director)Josh Hoffman(Founder)inEnakshi Singh(Executive Officer)Aaron Kimball(Executive Officer)
Co-investorsAME Cloud VenturesCota CapitalDCVC (Data Collective)Hemisphere Ventures LLCKindred VenturesMission Biocapital+6 more
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Wings Capital PartnersAnkiAnsel HealthBark TechnologiesBoundless ImmigrationDistributionalPer Diem Subscriptions, Inc.Rethink RoboticsSmall MoleculesSpellWalden RoboticsXilis, Inc.
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Exits · 4
2 IPOs · 2 acquisitionsDevvStreamOTC: DEVSFXCF GlobalNASDAQ: SAFXCoverWalletacq. by AonInsightSquaredacq. by Mediafly
Portfolio news
latest coverage across their companiesFacet · finsmes.com · Aug 28, 2026
XCF Global · stocktitan.net · Aug 27, 2026
Walden Robotics · assemblymag.com · Aug 24, 2026
Wealthsimple · investmentexecutive.com · Aug 21, 2026
Swarm Aero · defence-blog.com · Aug 11, 2026
Remote · defensedaily.com · Aug 3, 2026
Zymergen · claimdepot.com · Jul 27, 2026
Osmo · venturecapitaltracker.com · Jul 25, 2026
Frequently asked questions
- How many investments has Two Sigma Ventures made?
- Two Sigma Ventures has 69 tracked investments, 4 of which have exited, including 17 dated in the last 24 months.
- What stage does Two Sigma Ventures invest at?
- Two Sigma Ventures invests at the Seed, Series A, Series B stages.
- What is Two Sigma Ventures's typical check size?
- Two Sigma Ventures typically writes checks of $2M – $15M.
- What sectors does Two Sigma Ventures focus on?
- Two Sigma Ventures focuses on Biotech, Consumer, Data & Infrastructure, EdTech, Enterprise Software, Fintech, Hardware, Healthtech, SaaS, Sector Agnostic.
- Where is Two Sigma Ventures located?
- Two Sigma Ventures is headquartered in New York, US.
- Does Two Sigma Ventures lead rounds?
- Yes, Two Sigma Ventures leads investment rounds.
- Who does Two Sigma Ventures co-invest with?
- Two Sigma Ventures most often shares deals with DST Global, Greylock Partners, ICONIQ, among 16 tracked co-investors.
Media · Podcasts & interviews
featuring the teamInvesting in Disruptive Tech for Manufacturing Industry - Colin Beirne, Two Sigma Ventures #shorts
VentureFizz · Colin Beirne
#125 Frances Schwiep | Partner @ Two Sigma Ventures - WIN/WIN: Women in Innovation | Acast
Frances Schwiep · shows.acast.com
The People of Two Sigma | Jin, Quantitative Researcher
Two Sigma
From Intern to Insider
Two Sigma
Co-investors · 127
Founder Collective is a seed and pre-seed stage venture capital firm that invests across sectors, describing itself as sector agnostic and anti-thematic.
Andreessen Horowitz (a16z) is a venture capital firm founded in 2009 by Marc Andreessen and Ben Horowitz, known for pioneering the platform model with a large team of operators supporting founders across stages.
Alumni Ventures (AV) is a venture capital firm that co-invests alongside lead VCs in startups, backing founders with capital and access to a large investor and operator community.
Tiger Global Management operates public equity strategies (long/short, long-focused and crossover) and a private equity business investing in early- through late-stage growth companies across new and existing industries.
Lux Capital is a venture capital firm that backs founders building transformative deep technologies, having been among the first investors in category-defining companies across AI, robotics, biotech, defense, and infrastructure.
Foundry invests in early-stage startups and venture funds across multiple sectors. The firm builds a portfolio-based network connecting portfolio companies with other investors and entrepreneurs.
Founders Fund is a venture capital firm that backs technology companies building transformative products.
Accel is a venture capital firm that partners with exceptional teams, positioning itself as a first partner to founders globally.
Techstars is a startup accelerator and early-stage investor that funds ambitious founders and provides capital, mentorship, and access to a global network of investors, operators, and corporate partners.
Index Ventures is a multi-stage venture capital firm that backs companies from Seed to IPO and beyond, including through its dedicated seed fund Index Origin.
First Round Capital is an early-stage venture firm that backs companies at their earliest moments, often before they are named, across enterprise, AI, consumer, healthcare, fintech and hardware sectors.
▶115 more co-investors
DCVC (Data Collective)SoftBank Vision FundScribble VenturesThe Column GroupSequoia CapitalRedpoint VenturesNotable CapitalCoatue ManagementGradient VenturesSusa VenturesMadrona Venture GroupScale Venture PartnersAmplify Partners8VCAccompliceHomebrewConstruct CapitalDesigner FundInkefGV (Google Ventures)Greylock PartnersUncork CapitalInsight PartnersBenchmarkTrue VenturesCRV (Charles River Ventures)FirstMark CapitalBling CapitalInnovation EndeavorsAfore CapitalResolute VenturesSouth Park CommonsF-Prime CapitalElectric CapitalPrimary Venture PartnersAIX VenturesWorklife Ventures23andMeICONIQ CapitalWork-BenchHeavybitBaruch Future VenturesFika9Yards CapitalWhat If VenturesRA CapitalBootstrapLabsDay One VenturesDigitalis VenturesBrewer Lane VenturesIngeborg InvestmentsNextech InvestMPG FundGood Growth CapitalGovtech FundOverwater Ventures LlcLong Journey VenturesBoxGroupSound VenturesAtomicoGoat CapitalPartech VenturesFundersClubOak HC/FTFreestyle CapitalForerunner VenturesCaffeinated CapitalLookout VenturesEmergence Capital PartnersStellar CapitalAdditionBowery CapitalIA VenturesSoma CapitalCrosslink CapitalRed Swan VenturesRevolutionTrajectory VenturesOperator LPBase10 PartnersDCM VenturesBlockchain CapitalPareto HoldingsTribe Capital FirstlookCoinbase VenturesCiti VenturesFuel CapitalAugust Capital468 CapitalARCH Venture PartnersFuture Perfect VenturesZ47Presence CapitalConvective CapitalRace CapitalOpenView Venture PartnersPortage VenturesAV8 VenturesBasecamp FundAsset Management VenturesFirsthandVCEight Roads VenturesSignal Peak VenturesA*EVE AtlasHorizonIndie.vcAudaciousDTCPSTILLMARKUnicorn India VenturesNew Markets Venture PartnersAmerica's Frontier FundBonsal CapitalMetalayer
Firms observed investing alongside Two Sigma Ventures, from public investor directories. Shared companies are the overlap with Two Sigma Ventures's recorded portfolio.
Similar investors
OMERS Ventures is a venture capital firm that invests in founders globally, with investment teams based in New York, Palo Alto, and Toronto.
The Alibaba Entrepreneurs Fund is a not-for-profit initiative of Alibaba Group that provides investment capital and strategic guidance to entrepreneurs and young people, focusing on Hong Kong and Taiwan-nexus startups.
SBI Investment Korea is a Korean asset management firm within the SBI Group that operates venture capital and private equity funds, positioning itself as a 'New Industry Creator'.
Good Growth Capital is a venture firm that invests exclusively in impact sectors aligned with the UN Sustainable Development Goals, pursuing strong financial returns while meeting diversity and UNDP impact metrics across its portfolio.
Volcanics Venture invests in companies operating in internet innovation, intelligent technology, and healthcare sectors. The firm provides capital and support services to entrepreneurs in these focus areas.