7wire Ventures
Venture capitalActively deployingChicago · Seed–Growth · 15 people tracked
Also known as 7WIRE MANAGEMENT, L.P. · 7wire Ventures GO · 7wire Ventures GO 2022
Investment thesis
7wire Ventures backs early-stage, technology-enabled healthcare and digital health companies aiming to 'rewire' the status quo in health and care. Its central thesis centers on creating Informed Connected Health Consumers, supporting founders building consumer-directed technologies across areas such as autoimmune and digestive care, women's health, Medicaid populations, and AI applications in healthcare. Beyond capital, the firm positions itself as a partner of experienced healthcare operators who are personally invested in each company's success, offering deep industry relationships and operational expertise to founders, limited partners, and strategic partners.
Source: firm website, verified Aug 25, 2026.
Team · 15 people
from the firm's website & public directories
Founder mafia
2 people who came through 7wire Ventures went on to found or lead other companies.
What they invest in
from 39 of 45 portfolio companiesHealthtech ×35Digital Health ×27SaaS ×8Wellness & Fitness ×8AI & Machine Learning ×6Medical Devices ×4Biotech ×2Consumer ×2
HQs:United States×33China×1India×1
Who they back
founder profiles across 16 portfolio companiesFounding team size:solo founder×82 founders×63 founders×2
Investments · 45 tracked
founders shown can be your intro pathBy year:2026 · 22025 · 32024 · 32023 · 12021 · 42020 · 12018 · 12017 · 12016 · 117 dated
PayZen provides AI-powered, interest-free patient financing that lets patients pay medical bills over time through personalized payment plans, with pre-built EHR integrations and automated servicing for providers.
AI & Machine LearningDigital HealthFintechHealthtechSan Francisco, US
Tobias Mezger(Executive Officer, Director)inIsaac Cohen(Executive Officer, Director)Ariel Rosenthal(Co-Founder & CTO)inItzik Cohen(Co-Founder & CEO)inAntonio Martino(Executive Officer)
Board seatLee Shapiro· per SEC Form D
Co-investorsSignalFireCorewell Health VenturesHaymaker VenturesLink VenturesLorimer VenturesNew Enterprise Associates (NEA)+3 more
HealthtechChicago, US
David Greenberg(Executive Officer, Director)Tom Main(Director)David Jacobs(Executive Officer, Director)
Board seatGlen TullmanLee Shapiro· per SEC Form D · $6M raise · filed Oct 2018
Click Therapeutics develops, validates, and commercializes software-based prescription medical treatments, including software-enhanced drug products that combine digital therapeutics with pharmacotherapy.
BiotechDigital HealthHealthtechMedical DevicesNew York, US
David B. Klein(Founder and CEO)Randall Stanicky(Executive Officer)David Klein(Executive Officer, Director)
BoardAlex Zisson(Director)Cris De Luca(Director)in
Board seatLee Shapiro· per SEC Form D · $48.6M raise · filed Apr 2025
Co-investorsAccelmed PartnersH.I.G. CapitalH.I.G. HealthBridge PartnersHealth Catalyst CapitalHikma VenturesSanofi Ventures+2 more
BiotechHuntsville, US
James Hudson(Director)David Bick(Executive Officer)Elizabeth Worthey(Executive Officer)Bruce Korf(Executive Officer)Jason Chung(Director)Howard Jacob(Director)
Board seatThomas Main· per SEC Form D · $3M raise · filed Dec 2017
HealthtechDayton, US
Kili Preitauer(Executive Officer, Director)David Shulkin(Executive Officer, Director)Jennifer Shulkin(Executive Officer, Director)
BoardDevin Carty(Director)Reena Pande(Director)
Board seatLee Shapiro· per SEC Form D · $2.5M raise · filed Jun 2026
GroundGame.Health operates a technology platform and hyperlocal operating model that connects health plans, providers, employers, and community-based organizations to address barriers to care and social determinants of health.
Digital HealthHealthtechImpact & Social GoodSocialTampa, US
Susan Rawlings Molina(Executive Officer, Director, Promoter)inSridhar Akula(Executive Officer, Director)Aimee Dailey(Director)
BoardShantanu Agrawal(Director)Jennifer Jarrell(Director)
Board seatRobert Garber· per SEC Form D
Co-investorsCorewell Health VenturesMagnetic VenturesRaptor Group
Chicago, US
Jeffrey Bennett(Executive Officer, Director)John Collins(Director)William Wrigley, Jr.(Director)Peter Neupert(Director)Leslie Davies(Director)Robert Wah(Director)
Board seatGlen Tullman· per SEC Form D · $32.4M raise · filed Jun 2020
Co-investorsBlueCross BlueShield Venture PartnersFlare Capital Partners
Homethrive offers a caregiving support service that combines digital tools with access to human care experts to help working family caregivers manage care for their loved ones.
Digital HealthHealthtechHR TechSaaSWellness & FitnessNorthbrook, US
David Greenberg(Executive Officer, Director)inDavid Jacobs(Executive Officer, Director)Tom Archipley(Director)
BoardRavit Washa Dor(Director)Ittai Harel(Director)in
Board seatGlen TullmanRobert GarberLee Shapiro· per SEC Form D
Co-investorsCorewell Health VenturesHuman CapitalPitango
HealthtechNew York, US
Kira Wampler(Director)Dennis Yang(Executive Officer, Director)
Board seatLee Shapiro· per SEC Form D · $6.8M raise · filed Mar 2021
Khyaal is a mobile app that serves seniors in India with a community platform offering events (music, games, yoga, meditation), financial products (digital gold and SIPs), curated products through a marketplace, and organized senior-friendly domestic and international tours.
ConsumerFintechWellness & FitnessIndia, IN
Hemanshu Jain(Executive Officer, Director)Raj-Ann R. Gill(Director)
Board seatGlen Tullman· per SEC Form D · $5.4M raise · filed Oct 2023
Co-investorsSupermorpheus
NOCD provides specialized treatment for obsessive-compulsive disorder through live video sessions with OCD-trained therapists and 24/7 in-app support between sessions, using exposure and response prevention (ERP) therapy.
Digital HealthHealthtechMental HealthChicago, US
LARRY TRUSKY(Executive Officer)STEPHEN M. SMITH(Executive Officer, Director)Stephen Smith(Cofounder)
Board seatGlen Tullman· per SEC Form D
Co-investorsChicago VenturesCorewell Health VenturesF-Prime CapitalKaiser Permanente VenturesLongitude CapitalMeridian Street Capital+2 more
HealthtechSan Diego, US
Martyn Gross(Executive Officer, Director)Kathy Scott(Executive Officer)
BoardJohn Buhler(Director)Rex Bright(Director)David Hale(Director)
Board seatRobert Garber· per SEC Form D · $43M raise · filed Oct 2021
Co-investorsSV Health Investors
Washington, US
Shub Debgupta(Executive Officer, Director)David Ehrhardt(Executive Officer)
BoardRobert Proctor(Director)Frank Coliano(Director)Tom Byrd(Director)
Board seatGlen Tullman· per SEC Form D · $2.5M raise · filed May 2016
9amHealth provides virtual care for cardiometabolic conditions, offering weight management, diabetes care, and heart health treatment that combines prescription medication (including GLP-1s), lifestyle coaching, and lab testing.
Digital HealthHealthtechWellness & FitnessEncinitas, US
Frank Westermann(Executive Officer, Director)Anton Kittelberger(Founder)inMichael Hofner(Executive Officer)Avantika Waring(Executive Officer)Paul Geevarghese(Executive Officer)Bernhard Schandl(Executive Officer)
Co-investorsCalm/Storm VCCatalio Capital Management, LPHabitat PartnersHansmann Family OfficePUSH VenturesSemperVirens Venture Capital+1 more
Accolade provides virtual healthcare services including primary care, mental health therapy, and benefits navigation for employees and their families.
Digital HealthHealthtechSaaSPlymouth Meeting, US
Thomas K Spann(Executive Officer, Director)Steve Barnes(Executive Officer)Rajeev Singh(Chief Executive Officer)Debbie Cohen(Executive Officer)John Rollins(Executive Officer)Jeff Smith(Executive Officer)
Co-investorsAccretive, LLCAlumni VenturesAndreessen HorowitzBasecamp FundBlue Ivy VenturesCarrick Capital Partners+7 more
Allumia helps utilities design and manage energy efficiency programs from launch through measured results, and helps small and medium-sized businesses cut energy use through lighting, HVAC, and refrigeration upgrades.
CleantechClimate TechEnergyIoTSeattle, US
Aaron Block(Executive Officer, Director)Eyal Levy(Director)
Co-investorsCapital InnovatorsK Street CapitalSkyview VenturesAllumia Ventures
AVIA operates a network and advisory platform for health systems, providing benchmarking, market intelligence, and peer collaboration to support their digital transformation and AI adoption.
Digital HealthHealthtechSaaS
Linda Finkelin
Co-investorsOSF VenturesFirst Trust Capital Partners
Brightline provides mental health care for children, teens, and families, combining clinical care with technology.
Digital HealthHealthtechMental HealthBrooklyn, US
Naomi Allen(Co-founder & CEO)in
Co-investorsCity LightCorewell Health VenturesOak HC/FTOptum VenturesSemperVirens Venture CapitalThreshold Ventures
A women's+ digital company providing integrated mental, reproductive, and physical healthcare
Co-investorsCorewell Health VenturesGV (Google Ventures)MaveronThe Venture CollectiveIngeborg InvestmentsOMERS Ventures
Carebox builds AI-driven clinical trial matching technology (Carebox Connect) that indexes trial eligibility criteria to match patients' clinical and genomic profiles with relevant studies.
AI & Machine LearningDigital HealthHealthtechSaaS
Co-investorsCorewell Health VenturesH.I.G. CapitalH.I.G. Growth Partners
Co-investorsDrive Capital
CirrusMD offers a virtual primary care platform where patients connect with a physician via chat in under 60 seconds for diagnosis, treatment, and guidance to benefits and next steps in care.
Digital HealthHealthtechSaaSDenver, US
Andrew Altorfer(Chief Executive Officer)Wallace Blake McKinney(Director)Blake McKinney(Co-founder)JAMIE HALL(Executive Officer, Director, Promoter)JENNIFER PEARCE(Executive Officer)SCOTT REICH(Executive Officer)
Co-investorsBlue Venture FundsBootstrap Venture PartnersCorewell Health VenturesDrive CapitalRockies Venture Club
Cylinder Health is a data-driven digestive health organization that develops value-based care programs, products, and payment models in the gastrointestinal space.
Digital HealthHealthtech
Co-investorsBig Pi VenturesCorewell Health VenturesDistributed VenturesFCA Venture PartnersHealth Catalyst CapitalSemperVirens Venture Capital+3 more
FOLX is a digital healthcare platform designed for LGBTQIA+ adults, providing inclusive and affirming medical care.
Digital HealthHealthtechBoston, US
A.G. Breitenstein(Founder)inLena Ballantine(Executive Officer)Liana M Guzman Weis(Executive Officer, Director)
BoardLynne Chou O'Keefe(Director)inMorgan Cheatham(Director)inLee Shapiro(Director)in
Co-investorsBessemer Venture PartnersCorewell Health VenturesDefine VenturesHabitat PartnersSeae VenturesBreyer Capital+2 more
Higi is a consumer health engagement platform that enables individuals to measure, track, and act on their health data through a network of self-screening kiosks, home devices, and digital tools.
Digital HealthHealthtechWellness & Fitness
Co-investorsCorewell Health VenturesFlare Capital PartnersBlueCross BlueShield Venture Partners
Jasper provides one-on-one virtual supportive care guidance for cancer patients, delivered by oncology-trained counselors to help manage treatment side effects and survivorship challenges.
Digital HealthHealthtech
Co-investorsCorewell Health VenturesDeclaration PartnersHuman CapitalW Health Ventures Gp Llc
Lightbeam offers an AI-enabled population health platform along with actuarial and clinical advisory services to help hospitals and providers manage CMS value-based care models such as TEAM, ACCESS, and LEAD.
AI & Machine LearningDigital HealthHealthtechSaaS
Pat Cline(Executive Chairman & Founder)
Co-investorsBlue Hour VenturesNueterra CapitalVertex Ventures8VCVillage Global
Livongo offers a chronic condition management program combining connected health-monitoring devices (blood glucose meters, blood pressure monitors, scales), certified health coaches, and clinical support to help members manage diabetes, hypertension, and weight, including GLP-1 medication access.
Digital HealthHealthtechWellness & FitnessMountain View, US
JOSEPH E. CAREY(Executive Officer)BRIAN VANDENBERG(Executive Officer)MARIO CHRISTOPHER(Executive Officer)
BoardBETH SEIDENBERG(Board Director (Kleiner Perkins))inLEE SHAPIRO(Director)inHEMANT TANEJA(Director)in
Co-investorsCorewell Health VenturesGeneral CatalystHuman CapitalKleiner PerkinsSapphire VenturesSlow Ventures+4 more
MedArrive provides software for scheduling, routing, and real-time tracking of in-home care delivery teams.
HealthtechLogistics & Supply ChainSaaSNew York, US
Inna Plumb(Executive Officer)Daniel Trigub(Executive Officer, Director)
BoardWilliam Sullivan(Director)Annie Case(Director)inAndy Harrison(Director)Agneta Breitenstein(Director)in
Co-investorsCobalt VenturesCorewell Health VenturesDeclaration PartnersKleiner PerkinsDefine VenturesSection 32
Medisafe is a medication engagement platform that helps pharmaceutical companies connect with patients beyond the prescription and improve treatment adherence.
Digital HealthHealthtechMedical DevicesBoston, US
Rotem Shor(Founder)
Co-investorsALIVE Israel HealthTech FundCorewell Health VenturesLool VenturesM VenturesQualcomm VenturesSanofi Ventures+2 more
OM1 develops AI-powered analytics and data infrastructure for healthcare organizations to measure patient outcomes, predict health trajectories, and accelerate medical research using real-world clinical data.
AI & Machine LearningData & InfrastructureHealthtechMedical DevicesBoston, US
Richard Gliklich, MD(Founder)Richard E. Gliklich(Executive Officer, Director)
BoardRory O'Driscoll(Director)Larry Bohn(Director)David Barrett(Director)Gary Gottlieb(Director)
Co-investorsBreyer CapitalCorewell Health VenturesM33 GrowthScale Venture Partners
Override provides virtual, interdisciplinary chronic pain treatment that combines pain medicine, behavioral health, physical therapy, and coaching into one coordinated care team.
Digital HealthHealthtechWellness & Fitness
Co-investorsCorewell Health VenturesMartin Ventures
Parsley Health delivers evidence-based, whole-body functional medicine care through board-certified clinicians trained in functional medicine.
Digital HealthHealthtechWellness & FitnessNew York, US
Robin Berzin(Founder & CEO)Robin Berzin MD(Founder)in
Co-investorsAdvance Venture PartnersAlpha EdisonAmplo VenturesCorewell Health VenturesEvolution VC PartnersFirstMark Capital+10 more
Digital HealthHealthtechImpact & Social Good
Co-investorsCorewell Health VenturesMagnetic VenturesRaptor Group
SchoolCare provides a healthcare platform focused on improving health services for children, serving schools, parents, and payers.
Digital HealthEdTechHealthtechSaaSNew York, US
Co-investorsCorewell Health Ventures
Summer Health provides text-based, on-demand pediatric care that connects parents with doctors within minutes for their children's non-scheduled health needs.
ConsumerDigital HealthHealthtech
Co-investorsCoalition OperatorsCorewell Health VenturesIngeborg InvestmentsLux CapitalSequoia CapitalShrug Capital+5 more
TailorCare provides personalized specialty care for patients with musculoskeletal (MSK) conditions such as joint, back, and muscle pain, guiding them toward appropriate treatment plans.
Digital HealthHealthtech
Rachel Winokur(Chief Executive Officer)inJohn Petito(Chief Strategy Officer)Steve Tutewohl(Chief Operating Officer)Julie Sumrack(Chief People Officer)Kara Rios(Chief Financial Officer)Lucas Richie(Chief Medical Officer)
Co-investorsCorewell Health Ventures
Transcarent operates a generative AI-powered health and care platform that combines medical, pharmacy, and point solutions into a single member experience, helping people navigate the healthcare system and access on-demand care.
AI & Machine LearningDigital HealthHealthtechDenver, US
Co-investorsCorewell Health VenturesGeneral CatalystGeodesic CapitalGreatPoint VenturesHuman CapitalKinnevik+5 more
Advances digestive care; raised a $31M Series B.
Digital health company advancing digestive care.
HealthtechHouston, US
Sally Welborn(Director)William Snyder(Executive Officer, Director)Marco Veremis(Director)Shawn Ellis(Director)Sanford Duncan(Director)Andrew Bouldin(Director)
Zerigo Health develops technology-driven digital therapeutics and care solutions for individuals living with chronic skin conditions.
Digital HealthHealthtechMedical Devices
Co-investorsCorewell Health VenturesH.I.G. CapitalH.I.G. HealthBridge PartnersSV Health InvestorsAccelGeneral Catalyst+3 more
Welltheory offers evidence-based nutrition and lifestyle coaching for people with autoimmune conditions, including 1-1 coaching, unlimited messaging, personalized whole-body care plans, and access to testing and a patient community.
Digital HealthHealthtechWellness & FitnessSan Francisco, US
Ellen Rudolph(Cofounder)inWallace Torres(Founder)inZac Prutzman(Executive Officer)Claire Rudolph(Executive Officer, Director)Dan Rudolph(Executive Officer, Director)
BoardCandace Richardson(Director)
Co-investorsAccelCoalition OperatorsCorewell Health VenturesIngeborg InvestmentsSamsung NextScribble Ventures+2 more
When provides post-employment health coverage support, guiding departing employees, retirees, and dependents to COBRA alternatives such as ACA plans through an AI-powered plan navigator and concierge service.
AI & Machine LearningFuture of WorkHealthtechHR TechInsurTechChicago, US
Andrew Hamilton(Founder)Andy Hamilton(Founder & CEO)inDan Wertheimer(Founder & CSO)inBrook West(Chief Revenue Officer)inPatrick Koeller(CTO)in
Co-investorsB Capital GroupB4 CapitalChicago Early Growth Ventures (CEGV)Corewell Health VenturesManchesterStory Group, LLC
A Chinese electrical equipment manufacturer founded in 2004 in Jiangshan, Zhejiang, specializing in power/transmission and distribution equipment such as transformers.
Advanced ManufacturingEnergyHardwareJiangshan, CN
Wang Rong(Chairman)王荣(Chairman (董事长))
Co-investorsH.I.G. CapitalSV Health Investors
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Exits · 1
IPOs and acquisitions across the tracked portfolioSameskyacq. by GroundGame.Health
Portfolio news
latest coverage across their companies
Brightline · wptv.com · Aug 20, 2026
Override · thereadingobserver.com · Aug 14, 2026
When · yahoo.com · Aug 12, 2026
Cylinder · fiercehealthcare.com · Aug 5, 2026
Summer Health · mobihealthnews.com · Jul 29, 2026
Allumia · hitconsultant.net · Jul 23, 2026
Accolade · pulse2.com · Jul 19, 2026
Frequently asked questions
- How many investments has 7wire Ventures made?
- 7wire Ventures has 32 tracked investments, 1 of which have exited via acquisition or IPO, including 3 dated in the last 24 months.
- What stage does 7wire Ventures invest at?
- 7wire Ventures invests at the Seed, Series A, Series B, Growth stages.
- What is 7wire Ventures's typical check size?
- 7wire Ventures typically writes checks of $100K – $5M.
- What sectors does 7wire Ventures focus on?
- 7wire Ventures focuses on AI & Machine Learning, Digital Health, FemTech, Healthtech.
- Where is 7wire Ventures located?
- 7wire Ventures is headquartered in Chicago, US.
- Does 7wire Ventures lead rounds?
- Yes, 7wire Ventures leads investment rounds.
- Who does 7wire Ventures co-invest with?
- 7wire Ventures most often shares deals with Corewell Health Ventures, Human Capital, SemperVirens Venture Capital, among 100 tracked co-investors.
From the blog
visit blog ↗7wire Ventures recently featured perspectives on digital pediatric mental health delivery and the behavioral health sector's evolution from access-focused to outcome-accountable models. The firm is actively investing in early-stage healthcare companies, welcoming a new principal with experience in digital health and strategy roles. AI summary
Media · Podcasts & interviews
featuring the teamWhat's Next In Digital Health? Lee Shapiro of 7wire Ventures and the American Heart Association
Get Real with Jim Weiss · Lee Shapiro
Glen Tullman on Building What Works: Lessons from Transcarent, 7wire Ventures, and StartUp Health
StartUp Health · Glen Tullman
Lee Shapiro on 7wire Ventures | Building Informed & Connected Health Consumers
Analyzing Healthcare by SCALE Community · Lee Shapiro
Lee Shapiro | How 7wire Ventures Invests in Accessible & Affordable Healthcare
Analyzing Healthcare by SCALE Community · Lee Shapiro
Collaborative Innovations: Navigating Digital Health Fundraising with Lee Shapiro of 7wire Ventures
StartUp Health · Lee Shapiro
Interview in Action @ HLTH '22 - Lee Shapiro, Managing Partner at 7wire Ventures
This Week Health · Lee Shapiro
Images
Co-investors · 32
Define Ventures is an early-stage venture firm focused on health technology companies, partnering with founders building at the intersection of healthcare and technology.
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General Catalyst is a venture capital firm operating as a partnership focused on company building and accelerating the growth of the businesses it backs.
Threshold Ventures is a venture capital firm that partners with founder-led companies at inflection points of breakout growth, engaging early and providing hands-on advice during moments of market transformation.
SV Health Investors is a healthcare-focused investment firm that invests across multiple stages, geographies and healthcare sectors.
Ingeborg invests directly in early-stage, women-led startups with a focus on innovations improving motherhood, career, financial security, women's health, and living conditions. The firm also makes select investments in later-stage companies and women-led venture or private equity funds.
Sequoia Capital is a venture capital firm that partners with founders to build technology companies.
GV (Google Ventures) is a venture capital firm that has invested in artificial intelligence and machine learning since its early days, building a global portfolio of more than 100 AI companies across infrastructure, life sciences, and applications.
New Enterprise Associates (NEA) is a venture capital firm that invests in and provides long-term support to founders building new companies.
Alumni Ventures (AV) is a venture capital firm that co-invests alongside lead VCs in startups, backing founders with capital and access to a large investor and operator community.
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B Capital is a global investment firm backing early to late-stage technology innovators across technology, healthcare, and energy & resilience sectors.
Oak HC/FT is a growth equity firm that partners with founders building companies in healthcare and financial services, leveraging sector expertise and networks.
Lux Capital is a venture capital firm that backs founders building transformative deep technologies, having been among the first investors in category-defining companies across AI, robotics, biotech, defense, and infrastructure.
▶20 more co-investors
SignalFirePICUS CAPITALF-Prime CapitalMaveronViola VenturesOMERS VenturesPitangoOptum VenturesFounders FundEverywhere VenturesACME CapitalLatitud VenturesARCH Venture Partnersxfactor venturesS32Cherubic VenturesInventus Capital PartnersDigitalis VenturesTown Hall VenturesMercato Partners
Firms observed investing alongside 7wire Ventures, from public investor directories. Shared companies are the overlap with 7wire Ventures's recorded portfolio.
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