Flagship Ventures
Venture capitalCambridge · 3 people tracked
Also known as Flagship Capital Management Inc
Find your way into Flagship Ventures
11 people in our graph share verified history with the Flagship Ventures team — schools, employers, funds. One of them is your warm intro.
Fund manager profile
Flagship Ventures is a venture fund manager based in Cambridge. SEC filings show 2 venture funds on record, most recently Flagship Ventures Opportunities Fund I, L.P. ($350M offering) filed June 2016.
Source: SEC EDGAR Form D filings. Firm website data not yet available.
Team · 3 people
from public directoriesFounder mafia
4 people who came through Flagship Ventures went on to found or lead other companies.
What they invest in
from 5 of 6 portfolio companiesBiotech ×5Healthtech ×1Medical Devices ×1
HQs:United States×4
Investments · 6 tracked
founders shown can be your intro pathBy year:2022 · 12020 · 12 dated
Agios is a biopharmaceutical company developing therapies for rare diseases, with a primary focus on hemolytic anemias including pyruvate kinase deficiency, thalassemia, and sickle cell disease.
BiotechHealthtechMedical Devices
Lewis C. Cantley, Ph.D.(Founder)Tak Mak, Ph.D.(Founder)Craig B. Thompson, M.D.(Founder)Brian Goff(Chief Executive Officer)in
Co-investorsARCH Venture PartnersThird Rock VenturesSamsara BioCapital
BiotechCambridge, US
Robert Connelly(Executive Officer, Director)Garry Menzel(Executive Officer)Jeff Moore(Executive Officer)
BoardJohn Mendlein(Director)David Berry(Director)inNoubar Afeyan(Director)in
Co-investorsFidelity InvestmentsFlagship Pioneering
BiotechCambridge, US
Torben Straight Nissen(Executive Officer, Director)inJoanne Protano(Executive Officer)inDavid Epstein(Director)Harvey F. Lodish(Director)Michael Rosenblatt(Director)Roger Pomerantz(Director)
Co-investorsFlagship PioneeringKendall Capital Partners
BiotechCambridge, US
HOWARD BERNSTEIN(Executive Officer)HOWARD WEISMAN(Executive Officer, Director)
BoardALAN CRANE(Director)ROBERT LANGER(Director)ANUPENDRA SHARMA(Director)HARRY WILCOX(Director)
Co-investorsFlagship PioneeringNewpath PartnersPolaris Partners
Syros Pharmaceuticals is a Massachusetts gene-control biotech developing small molecules that regulate disease gene expression.
Co-investorsAisling CapitalARCH Venture PartnersQuan CapitalREDMILE
BiotechWatertown, US
Guy Macdonald(Director)inLarry Edwards(Executive Officer, Director)inMaria Stahl(Executive Officer)inChristopher Watt(Executive Officer)
BoardL. Patrick Gage(Director)Keith Maher(Director)
Co-investorsBay City CapitalF-Prime CapitalExcel Venture ManagementMediphase Venture Partners
Exits · 1
IPOs and acquisitions across the tracked portfolioAgios PharmaceuticalsNASDAQ: AGIO
Portfolio news
latest coverage across their companies
Agios Pharmaceuticals · sahmcapital.com · Jul 15, 2026
Syros · ad-hoc-news.de · May 14, 2026
Fund performance · per public LP disclosures · 2
as of Dec 2025| Fund | Vintage | Committed | Net IRR | TVPI | DPI |
|---|---|---|---|---|---|
| Flagship Pioneering – Origination Fund VII, L.P.LPs: Texas Municipal Retirement System, Michigan Municipal Employees' Retirement System | — | — | 12.6% | 1.33x | 0.00x |
| Flagship Pioneering Fund VIII, L.P.LPs: Michigan Municipal Employees' Retirement System, Texas Municipal Retirement System | — | — | 18.1% | 1.17x | 0.00x |
Source: public limited-partner disclosures (CalPERS, CalSTRS). Net IRR / TVPI / DPI as reported by the limited partner; a fund's early-year IRR is an interim estimate (J-curve).
Frequently asked questions
- Where is Flagship Ventures located?
- Flagship Ventures is headquartered in Cambridge, US.