🦊/Investors

RA Capital

Crossover fundActively deploying

Boston · Seed–Late Stage · 86 people tracked

Also known as RA CAPITAL MANAGEMENT, LP · RA Capital Nexus · RA Capital Nexus International · RA Capital Planetary Health · RA Capital Planetary Health International

Find your way into RA Capital

2,561 people in our graph share verified history with the RA Capital team — schools, employers, funds. One of them is your warm intro.

Kyle Dohertyunlockedknows Jake Simson · together at Massachusetts Institute of Technology (overlapped)
knows the team · via Yale University
×2knows the team · via Harvard University
×2knows the team · via Massachusetts Institute of Technology
×2knows the team · via Cornell
knows the team · via College of the Holy Cross
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Investment thesis

RA Capital pursues evidence-based, full-lifecycle investing across healthcare, life sciences, and planetary health. It provides multi-stage capital spanning private and public markets, from new company creation and seed-stage incubation through venture rounds, crossover financing, IPO, and later-stage public investing. The firm emphasizes deep landscape research, scientific diligence, and operational company-building support, backed by a team of over 200 people with scientific and operational depth. In healthcare it partners early to shape strategy and define proof points, then provides capital continuity through growth. Its planetary health arm targets near-market, scalable companies advancing resource availability, energy innovation, and industrial productivity. Its Raven platform incubates and co-creates companies to address unmet biomedical needs.

Source: firm website, verified Sep 22, 2026.

Stage
Seed–Late Stage
HQ
Boston, Massachusetts, US
Instruments
Equity
Founded
2004
Last 12 months
37 investments
AUM
$16.4B
Tracked investments
353
Unicorns
23
IPOs
67
Acquisitions
35

Team · 86 people

from the firm's website & curated & public directories
Brigid O’Brien· Managing Partner
Brigid O'Brien· General Partnerin
Jeremy Lack· Partner
Matt Hammond· Partnerin
Emory Werner· Investment Director, Venturein
Jonathan Pritz· Investment Director, Venturein
Megan Lipcsey· Investment Director
Tess Cameron· Managing Director, Venturein
Anish Suri· Consulting Venture Partner
Bimal Shah· Venture Partner
David Weinstock· Venture Partner
Fanny Cavalié· Venture Partner
Gerald Sewack· Venture Partnerin
Jacob Oppenheim· Venture Partner
Nithya Desikan· Venture Partner
Paul Rothman· Venture Partner
Robert Nicol· Venture Partner
Albert Kim· Advisor
Alex Miller· Senior Associate, Venturein
Alison Tisdale· Advisor
Dan Grau· Advisor
Eric Wei· Associate, Structured Capitalin
Henry Stusnick· Analystin
Joel Barrish· Advisor
Julie Gupta· Senior Associate, Corporate Development, Venturein
Justin Waney· Vice President, Structured Capitalin
Kurt Armbrust· Entrepreneur in Residence
Matt Stanton· Advisor
Michael Sherman· Advisor
Mike Cloonan· Advisor
Neil Buckley· Advisor
Pat Schnettler· Senior Associatein
Sadik Kassim· Advisor
Sophie Papa· Advisor
Tyler Carney· Associate, Structured Capitalin
Michael Saulnier· Directorin
Sinead Wagner· Director
Tammy Seymour· Director

7 people who came through RA Capital went on to found or lead other companies.

What they invest in

from 257 of 353 portfolio companies

Biotech ×213Healthtech ×131Medical Devices ×83Deep Tech ×28Digital Health ×28AI & Machine Learning ×22Cleantech ×7Climate Tech ×6

HQs:United States×195United Kingdom×4Denmark×3Switzerland×2China×2Germany×2

Who they back

founder profiles across 99 portfolio companies
44%
solo founders
44 of 99 mapped founding teams
32%
repeat founders
of 85 founders with career history
~4 yrs
old at investment
median across 59 dated deals

Founding team size:solo founder×442 founders×363 founders×144+ founders×5

Where their founders studiedfrom 75 founders with education data

Massachusetts Institute of Technology ×9Harvard Business School ×5University of California, Berkeley ×5Stanford University ×4Dartmouth College ×3Harvard University ×3Heidelberg University ×3Stanford University School of Medicine ×3

What their founders studiedfrom 75 founders with field-of-study data

Life Sciences ×35Engineering ×16Business & Management ×12Medicine ×11Chemistry ×10Computer Science ×10Finance & Accounting ×7Physics ×6

Where their founders worked beforefrom 85 founders with career history

MPM BioImpact ×5Harvard Medical School ×4Johnson & Johnson ×4Celsius Therapeutics ×2ClarVista Medical ×2Curie.Bio ×2ETH Zurich ×2iRobot ×2

Accelerator rootsportfolio companies that came through a program

Y Combinator ×2

46 founders hold a PhD · 13 hold an MBA (of 77 with degree data)

Investments · 353 tracked

founders shown can be your intro path

By year:2026 · 272025 · 212024 · 192023 · 72022 · 122021 · 252020 · 132019 · 72018 · 72017 · 42016 · 42015 · 8157 dated

Freenomefreenome.comin𝕏NASDAQ: FRNMSeries B · Oct 2015 · $160M✓ verified

Freenome develops early-stage cancer detection technology using blood tests to identify cancer in its earliest, most treatable phases.

AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesLondon

Riley Ennis(Co-Founder and Chief Product Officer)inCharles Roberts(Director)inGabriel Otte(Director)inAdam Stone(Chief Executive Officer and Director)Michael Altman(Chief Business Officer and Director)Shmuel (Sam) M. Cohn(Chief Financial Officer)

Co-investorsAgent CapitalAME Cloud VenturesAndreessen HorowitzArtis VenturesAsset Management CompanyAverin Capital+9 more

Sionnatxsionnatx.comin𝕏NASDAQ: SION✓ verified

Sionna Therapeutics is a biopharmaceutical company founded in 2019 that develops small-molecule therapies for cystic fibrosis by targeting and stabilizing NBD1, the domain of the CFTR protein where the common ΔF508 mutation occurs.

BiotechHealthtechMedical Devices

Greg(Co-founder & Senior Vice President of Discovery Research)Mark(Co-founder & Senior Vice President of Medicinal Chemistry)Mike(President & CEO)Charlotte(Chief Medical Officer)Elena(Chief Financial Officer)Caroline(Chief Business Officer)

Co-investorsAtlas VentureOrbiMed

Mineralys Therapeuticsmineralystx.comin𝕏NASDAQ: MLYSJun 2022

Mineralys Therapeutics is a clinical-stage pharmaceutical company developing lorundrostat, a treatment targeting dysregulated aldosterone.

BiotechHealthtechRadnor, US

Eric Warren(Chief Commercial Officer)inAlex Gold(Chief Medical Officer)inAdam Levy(Executive Officer)Alexander Asam(Director)

BoardBrian Taylor Slingsby(Founder & former CEO / Board Director)Olivier Litzka(Director)in

Board seatDerek DiRocco· per SEC Form D

Co-investorsAndera PartnersSamsara BioCapitalSR One Capital ManagementYsios CapitalAdams Street PartnersBoulder Ventures+1 more

Spero Therapeuticssperotherapeutics.cominNASDAQ: SPROMar 2017

Spero Therapeutics is a clinical-stage biopharmaceutical company developing medicines for immune-mediated diseases, led by SP001, a third-generation anti-CD40L antibody targeting IgG4-related disease.

BiotechCambridge, US

Ankit Mahadevia(Executive Officer, Director)inStephen Garbacz(Executive Officer)inEsther Rajavelu(Director, President, Chief Executive Officer, Chief Financial Officer, Chief Business Officer and Treasurer)in

BoardJean-Francois Formela(Director)inCasper Breum(Director)

Board seatReza Halse· per SEC Form D

Co-investorsHEALTHCARE ROYALTY PARTNERSMRL Ventures FundOUP (Osage University Partners)AlphabetAtlas VentureFidelity Investments

Wave Life Scienceswavelifesciences.comin𝕏NASDAQ: WVEJan 2015

Wave Life Sciences develops RNA-targeting therapeutics using RNA-editing modalities and chemistry to treat rare and common diseases, with a clinical pipeline addressing Alpha-1 antitrypsin deficiency, Duchenne muscular dystrophy, Huntington's disease, and obesity.

BiotechHealthtechLongevitySingapore

Takeshi Wada(Director)inGregory L. Verdine(Director)Paul B. Bolno, M.D.(Executive Officer, Director)in

BoardKen Takanashi(Director)Masaharu Tanaka(Director)

Board seatPeter Kolchinsky· per SEC Form D

Co-investorsForesite Capital

Aclaris Therapeuticsaclaristx.comNASDAQ: ACRS

Aclaris develops investigational monoclonal antibodies and small-molecule inhibitors targeting immune pathways for the treatment of atopic, autoimmune, and respiratory diseases.

BiotechHealthtechMedical DevicesWayne, US

Neal Walker(Executive Officer, Director)Kamil Ali-Jackson(Executive Officer)Stuart D. Shanler(Executive Officer)inJoseph Monahan(Executive Officer)inHugh Davis(Executive Officer, Director)inJames Loerop(Executive Officer)

Co-investorsAisling CapitalAPERTURE Venture PartnersF-Prime CapitalForesite CapitalSofinnova VenturesSofinnova Venture Partners+1 more

Adagio Medicaladagiomedical.comNASDAQ: ADGM

Adagio Medical develops and commercializes catheter-based cardiac ablation devices using proprietary Ultra-Low Temperature Ablation (ULTA) technology to treat ventricular tachycardia and other cardiac arrhythmias.

HealthtechLaguna Hills, US

Olav Bergheim(Executive Officer, Director)Andrew Wade(Executive Officer)Hugh Neuharth(Executive Officer)Todd Usen(Chief Executive Officer and Director)inDeborah Kaster(Chief Financial Officer and Chief Business Officer)in

BoardMichael Zhao(Director)

Adagio Medical HoldingsNASDAQ: ADGMOct 2025

Adagio Medical Holdings develops and commercializes catheter-based ablation devices using proprietary Ultra-Low Temperature Ablation technology to treat ventricular tachycardia, a life-threatening abnormal heart rhythm, primarily in patients with structural heart disease.

HealthtechLaguna Hills, US

Todd Usen(Executive Officer, Director)inDeborah Kaster(Executive Officer)in

BoardKeyvan Mirsaeedi-Farahani(Director)Orly Mishan(Director)James L. Cox(Director)Timothy P. Moran(Director)

Adagio TherapeuticsNASDAQ: IVVDApr 2021 · $336M

Invivyd develops monoclonal antibody therapies to prevent and treat serious viral infections, beginning with COVID-19 and expanding to respiratory syncytial virus and measles.

BiotechWaltham, US

Tillman U. Gerngross(Executive Officer, Director)Lynn Connolly(Executive Officer)Eric Kimble(Executive Officer)inHalley Gilbert(Executive Officer)Rebecca Dabora(Executive Officer)inEllie Hershberger(Executive Officer)

Co-investorsFidelity InvestmentsForesite CapitalGV (Google Ventures)MITHRILMithril Capital ManagementOrbiMed+3 more

Aeglea BiotherapeuticsinNASDAQ: SYREacquired by Spyre Therapeutics · Nov 2023

Spyre Therapeutics develops monoclonal antibodies with extended half-lives targeting inflammatory bowel disease and rheumatic conditions including rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis.

BiotechAustin, US

David G. Lowe(Executive Officer, Director)George Georgiou(Director)Charles N. York(Executive Officer)inCameron Turtle(Chief Executive Officer and Director)

BoardHenry Skinner(Director)Armen Shanafelt(Director)

Agenusagenusbio.comNASDAQ: AGENAug 2026

Agenus is a biotechnology company developing cancer immunotherapies, including its lead investigational combination of botensilimab (an anti-CTLA-4 antibody) and balstilimab (a PD-1 inhibitor), known as BOT+BAL.

BiotechHealthtechLexington, US

Garo Armen(Chairman & CEO, Co-founder)Ozer Baysal(Executive Officer)Robert Stein(Executive Officer)Christine Klaskin(Executive Officer)inKaren Valentine(Executive Officer)Steven O'Day(Chief Medical Officer)in

Co-investorsAdvent Life SciencesGrazia Equity GmbHHEALTHCARE ROYALTY PARTNERSOberland CapitalCommodore CapitalInvus+1 more

Aktis Oncologyaktisoncology.cominNASDAQ: AKTSSep 2024 · $318M

Aktis Oncology discovers and develops targeted radiopharmaceuticals for treating solid tumors.

BiotechHealthtechMedical DevicesBoston, US

Todd Foley(Co-founder and Chairman)inPatrick Baeuerle(Co-founder & Advisor)inShulamit Ron-Bigger(Executive Officer)inKyle D. Kuvalanka(Chief Financial Officer)inAkos Czibere(Chief Medical Officer)inPaul L. Feldman(Chief Scientific Officer)in

Co-investorsAndreessen HorowitzEcoR1 CapitalMPM BioImpactMRL Ventures FundPappas CapitalTCG Crossover+5 more

AN2 Therapeuticsan2therapeutics.cominNASDAQ: ANTXMar 2026

AN2 Therapeutics is a clinical-stage biopharmaceutical company developing small-molecule drugs from its boron chemistry platform, with a pipeline spanning hematologic diseases, infectious diseases, oncology, and bone disorders.

BiotechHealthtechMenlo Park, US

Joseph S. Zakrzewski(Co-Founder & Director)Eric Easom(Co-Founder, President & CEO)inGeorge H. Talbot(Co-Founder & Senior Clinical Advisor)Michael R.K. (Dickon) Alley(Co-Founder, SVP Research Fellow, Head of Biology)Sanjay Chanda(Chief Development Officer)inLucy O. Day(Chief Financial Officer)in

Co-investorsAdjuvant CapitalBioRock VenturesFlucas VenturesMountain Group CapitalBiotechnology Value FundHatteras Venture Partners

Apogee Therapeuticsapogeetherapeutics.cominNASDAQ: APGE

Apogee Therapeutics develops engineered antibody therapies to treat inflammatory and immune diseases with reduced injection frequency compared to existing treatments.

BiotechHealthtechMedical Devices

Michael Henderson(Chief Executive Officer and Director)in

Co-investorsAccess BiotechnologyBlackstone Life SciencesPerceptive Xontogeny VentureRTW Investments L.P.Venrock Healthcare Capital Partners

Arcutisarcutis.comin𝕏NASDAQ: ARQTOct 2019

Arcutis is a biopharmaceutical company focused on dermatology, developing treatments for immune-mediated skin diseases such as plaque psoriasis, atopic dermatitis, seborrheic dermatitis, and scalp psoriasis.

BiotechHealthtechMedical DevicesWestlake Village, US

Todd Franklin Watanabe(Executive Officer, Director)Alexander Asam(Director)Ricky Sun(Director)

BoardPatrick Heron(Director)inDaniel Estes(Director)inJonathan Silverstein(Director)

Co-investorsBain Capital Life SciencesFrazier Life Sciences

Arvinas Holding Co. LLCarvinas.comin𝕏NASDAQ: ARVN

Arvinas is a biopharmaceutical company developing PROTAC protein degrader therapies, with a pipeline focused on oncology and neurology.

BiotechHealthtechNew Haven, US

Sean Cassidy(Executive Officer)inManuel Litchman(Executive Officer, Director)inRandy Teel(President and Chief Executive Officer; Director)in

BoardStephen Squinto(Director)inLiam Ratcliffe(Director)inTim Shannon(Director)in

Co-investors5AM VenturesAccess BiotechnologyCanaan PartnersConnecticut InnovationsNextech InvestSolasta Ventures+1 more

Atea Pharmaceuticalsateapharma.comNASDAQ: AVIR

Atea is a clinical-stage biopharmaceutical company developing oral direct-acting antiviral therapies for single-stranded RNA viruses, currently focused on a bemnifosbuvir and ruzasvir regimen in Phase 3 development for hepatitis C virus (HCV).

BiotechHealthtechBoston, US

Jean-Pierre Sommadossi, Ph.D.(Executive Officer, Director)Jean-Pierre Sommadossi(President, CEO and Chairman of the Board)inAndrea Corcoran(Chief Financial Officer, Executive Vice President, Legal, and Secretary)Janet Hammond(Chief Development Officer)inMaria Arantxa Horga(Chief Medical Officer)inJohn Vavricka(Chief Commercial Officer)in

Co-investorsBain Capital Life Sciences

Bicara Therapeuticsbicara.comin𝕏NASDAQ: BCAX

Bicara Therapeutics is a clinical-stage biopharmaceutical company developing bifunctional antibody therapies that combine tumor-targeting with immune-modulating payloads to treat solid tumors.

Ivan Hyep(Chief Financial Officer and Treasurer)inLara Meisner(Chief Legal Officer, Compliance Officer and Corporate Secretary)inDavid Raben(Chief Medical Officer)in

Co-investorsAisling CapitalEight Roads VenturesF-Prime CapitalForesite CapitalPremji InvestRed Tree Venture+5 more

BioAge Labsbioagelabs.comin𝕏NASDAQ: BIOAFeb 2024

BIOAGE develops therapies targeting the molecular pathways that drive aging to increase healthspan and address age-related chronic diseases.

BiotechHealthtechLongevityRichmond, US

Kristen Fortney, PhD(Co-Founder, CEO)Eric Morgen, MD(Co-Founder, COO)Kristen Fortney(Executive Officer, Director)inEric Morgen(Director)inDov Goldstein(Executive Officer)in

BoardPatrick Enright(Director)in

Co-investorsAndreessen HorowitzElad GilFelicis VenturesIA Seed VenturesLongitude CapitalOrbiMed+5 more

Biohavenbiohaven.comin𝕏NYSE: BHVN

Biohaven is a pharmaceutical company that discovers, develops, and commercializes medications for neurological and neuropsychiatric diseases, including epilepsy, pain, mood disorders, OCD, spinocerebellar ataxia, and spinal muscular atrophy.

BiotechHealthtechMedical DevicesConnecticut, US

Vlad Coric, M.D.(Chairman & Chief Executive Officer)in

Co-investorsOberland CapitalSixth StreetBlackRock

Black Diamond Therapeutics, Incblackdiamondtherapeutics.comNASDAQ: BDTX

Black Diamond Therapeutics develops small-molecule kinase inhibitors targeting families of oncogenic mutations across cancer types, including its lead candidate silevertinib for EGFR-mutant lung cancer and glioblastoma.

Elizabeth Buck(Chief Scientific Officer)inBrent Hatzis-Schoch(Chief Operating Officer and General Counsel)inSergey Yurasov(Chief Medical Officer)inMelanie Morrison(Chief Development Officer)

Co-investorsLAVLilly Asia VenturesNew Enterprise Associates (NEA)Nextech InvestNSG VenturesVersant Ventures+3 more

Bolt Biotherapeuticsboltbio.comin𝕏NASDAQ: BOLT

Bolt Biotherapeutics is a clinical-stage biotech company developing novel immunotherapies that leverage innate immune system mechanisms to treat cancer.

BiotechHealthtechMedical DevicesSan Francisco, US

Dr. Edgar G. Engleman(Founder)

Co-investorsPfizer Venture InvestmentsSamsara BioCapitalSofinnova VenturesVivo CapitalNan Fung Life SciencesNovo Holdings+3 more

Boundless Bioboundlessbio.comin𝕏NASDAQ: BOLD

Boundless Bio develops precision oncology medicines targeting ecDNA-amplified cancers, specifically creating a new category of ecDNA-directed therapies for patients with oncogenic alterations.

BiotechMedical DevicesLa Jolla, US

Zachary D. Hornby(Executive Officer, Director)inRobert Doebele(Chief Medical Officer)inChristian Hassig(Chief Scientific Officer)Jessica Oien(Chief Legal Officer and Corporate Secretary)in

BoardBenjamin Cravatt, Ph.D.(Director)Kristina Burow(Director)in

Co-investorsARCH Venture PartnersNextech InvestNEXTECH ONCOLOGY SCSPSignalFire

C4 Therapeuticsc4therapeutics.comin𝕏NASDAQ: CCCCDec 2015

C4 Therapeutics develops targeted protein degradation medicines aimed at treating disease.

BiotechCambridge, US

Kenneth C. Anderson(Director)Andrew J. Hirsch(Director and Chief Executive Officer)in

BoardMarc Cohen(Executive Officer, Director)inJason Fisherman(Executive Officer, Director)Miles Stuchin(Director)Bruce Downey(Director)

Co-investors3E Bioventures CapitalBain Capital Life SciencesNextech InvestCobro Ventures

Century Therapeutics, Inc.centurytx.cominNASDAQ: IPSCFeb 2021

Century Therapeutics develops allogeneic, iPSC-derived cell therapies using gene editing and protein engineering for autoimmune diseases including type 1 diabetes and cancer.

AI & Machine LearningBiotechHealthtechMedical DevicesPhiladelphia, US

Osvaldo Flores, Ph.D.(Executive Officer, Director)Douglas Carr(Executive Officer)inBrent Pfeiffenberger(President and Chief Executive Officer)inGregory Russotti(Chief Technology and Manufacturing Officer)Chad Cowan(Chief Scientific Officer)in

BoardToshikazu Ban(Director)

Co-investorsCasdin CapitalVersant Ventures

Ceribellceribell.comin𝕏NASDAQ: CBLL

Ceribell is a medical technology company that develops products for detecting and monitoring seizures, including EEG-based diagnostic systems.

AI & Machine LearningDigital HealthHealthtechMedical DevicesSunnyvale, US

Josef Parvizi(Director)inXingjuan (Jane) Chao(President, CEO, Co-Founder & Director)inScott Blumberg(Executive Officer)inJoseph Taylor(Director)Raymond Woo(Executive Officer)David Stoffel(Executive Officer)

Co-investorsLongitude CapitalRed Tree VentureShangBay Capital LLCThe Rise Fund

CG Oncologycgoncology.comin𝕏NASDAQ: CGON

CG Oncology develops an investigational oncolytic immunotherapy for urologic cancer patients, specifically targeting BCG-unresponsive non-muscle invasive bladder cancer.

BiotechHealthtechMedical Devices

Arthur Kuan(Chairman and Chief Executive Officer)in

Co-investorsDecheng CapitalForesite CapitalLongitude CapitalPalm Drive CapitalTCG CrossoverACORN BIOVENTURES+2 more

ClimbbioNASDAQ: CLYM

Climbbio is a clinical-stage biotechnology company developing monoclonal antibodies targeting B-cell pathways for immune-mediated diseases including primary membranous nephropathy, immune thrombocytopenia, and systemic lupus erythematosus.

Andrew Levin(Director)Aoife Brennan(President and Chief Executive Officer, Director)

Collegium Pharmaceuticalcollegiumpharma.comin𝕏NASDAQ: COLL

Collegium Pharmaceutical is a biopharmaceutical company developing a portfolio of medications to treat serious medical conditions.

BiotechCanton, US

Michael Heffernan(Executive Officer, Director)inPaul Brannelly(Executive Officer)inVikram Karnani(President and Chief Executive Officer, and Director)in

BoardEran Nadav(Director)John Freund(Director)Patrick Heron(Director)in

Co-investorsAPERTURE Venture PartnersEcoR1 CapitalFrazier Life SciencesLongitude CapitalBoston Millennia Partners

Connect Biopharmaconnectbiopharma.cominNASDAQ: CNTB

Connect Biopharma is a clinical-stage biopharmaceutical company developing antibody-based therapies targeting inflammatory diseases such as atopic dermatitis and asthma.

BiotechHealthtechSan Diego, US

Barry D. Quart(Chief Executive Officer and Director)inDavid Szekeres(President)inKimberly J. Manhard(Executive Vice President, Chief Development Officer)in

Co-investorsCo-Win Ventures

Crineticscrinetics.comin𝕏NASDAQ: CRNX

Crinetics is a pharmaceutical company focused on discovering, developing, and commercializing therapies for endocrine diseases and endocrine-related conditions.

BiotechSan Diego, US

Richard Scott Struthers(Executive Officer, Director)Stephen F. Betz(Executive Officer)inStephen Betz(Chief Scientific Officer)inR. Scott Struthers(President, Chief Executive Officer and Director)inTobin Schilke(Chief Financial Officer)inIsabel Kalofonos(Chief Commercial Officer)in

Co-investors5AM VenturesForesite CapitalOrbiMedVivo Capital

Cytek Biosciencescytekbio.comin𝕏NASDAQ: CTKBOct 2020

Cytek Biosciences develops high-parametric analytical instruments and software that enable scientists at pharmaceutical companies, contract research organizations, and academic institutions to generate and analyze biological datasets.

BiotechDeep TechHardwareHealthtechMedical DevicesBellevue, US

Wenbin Jiang, Ph.D.(CEO and Chairman of the Board)Wenbin Jiang(Executive Officer, Director)inMing Yan, Ph.D.(Chief Technology Officer)Ming Yan(Executive Officer, Director)inJiecheng Zhang(Director)Allen Poirson(Director)

Co-investors3E Bioventures CapitalF-Prime CapitalNorthern Light Venture Capital

Damora TherapeuticsNASDAQ: DMRANov 2025 · $284.9M

Damora Therapeutics is a preclinical-stage biotechnology company that discovers and develops therapeutic candidates, including DMR-001, DMR-002, and DMR-003, with the goal of advancing treatments through investigational drug applications and clinical trials.

BiotechCopenhagen, US

Garrett Winslow(Executive Officer)inLori Firmani(Executive Officer)inHans T. Schambye(Executive Officer, Director)Jennifer Jarrett(President, Chief Executive Officer and Director)inBecker Hewes(Chief Medical Officer)Sherwin Sattarzadeh(Chief Operating Officer)

Co-investorsAccess BiotechnologyBAM ElevateBay City CapitalCommodore CapitalEIR VenturesForbion+6 more

Designtxdesigntx.cominNASDAQ: DSGNJan 2021

Design Therapeutics is a biopharmaceutical company developing small molecule therapeutic candidates for serious genetic diseases through its GeneTAC (Gene Targeted Chimera) platform.

BiotechMedical DevicesSolana Beach, US

Pratik Shah, Ph.D.(Executive Officer, Director)Aseem Z. Ansari, Ph.D.(Director)Sean Jeffries, Ph.D.(Executive Officer)

BoardSimeon George, M.D.(Director)Stella Xu, Ph.D.(Director)Rodney Lappe, Ph.D.(Director)

Co-investorsAvoro Capital AdvisorsQuan CapitalSR One Capital ManagementWestRiver GroupQuan Venture

Diffusion Pharmaceuticalscervomed.cominNASDAQ: CRVO

CervoMed is a clinical-stage biopharmaceutical company developing neflamapimod, an investigational drug for neurodegenerative diseases such as nonfluent variant primary progressive aphasia and frontotemporal dementia.

BiotechHealthtechCharlottesville, US

John L. Gainer(Executive Officer, Director)inDavid G. Kalergis(Executive Officer, Director)inDavid R. Jones(Executive Officer)inBen L. Shealy(Executive Officer)John Moynahan(Executive Officer)Stephen Simes(Executive Officer, Director)

Dyne Therapeuticsdyne-tx.comin𝕏NASDAQ: DYNAug 2020

Dyne Therapeutics develops targeted therapies for genetically driven neuromuscular diseases using its proprietary FORCE platform.

BiotechMedical DevicesWaltham, US

Romesh Subramanian, Ph.D.(Executive Officer)Richard Scalzo(Executive Officer)Joshua Brumm(Executive Officer, Director)Jonathan McNeill, M.D.(Executive Officer)inOxana Beskrovnaya, Ph.D.(Executive Officer)John G. Cox(Chief Executive Officer and President, Director)in

Co-investorsAtlas VentureMPM BioImpactVida VenturesForbionHercules Capital, Inc.

Eliem TherapeuticsNASDAQ: CLYMMay 2021

Eliem Therapeutics is a clinical-stage biotechnology company developing monoclonal antibodies targeting immune-mediated diseases, with budoprutug, an anti-CD19 antibody designed to deplete B cells in conditions including primary membranous nephropathy, immune thrombocytopenia, and systemic lupus erythematosus, and CLYM116, an anti-APRIL antibody for IgA nephropathy and related B-cell mediated diseases.

BiotechWilmington, US

Valerie Morisset(Executive Officer)inErin Lavelle(Executive Officer)inRobert Azelby(Executive Officer, Director)James Bucher(Executive Officer)Leone Patterson(Director)

BoardAdam Rosenberg(Director)

Co-investorsManta Ray VenturesAccess BiotechnologyACORN BIOVENTURES

Enliven Therapeuticsenliventherapeutics.cominNASDAQ: ELVN

Enliven Therapeutics is a clinical-stage biopharmaceutical company that discovers and develops small molecule therapeutics using a precision medicine approach, with a focus on oncology and hematology.

BiotechHealthtechBoulder, US

Sam Kintz(Co-founder and Head of Pipeline)inJoe Lyssikatos(Co-founder and Research Fellow)Anish Patel(Co-founder and Chief Operating Officer)Rick Fair(Chief Executive Officer and Member of the Board of Directors)inHelen Collins(Chief Medical Officer)inBen Hohl(Chief Financial Officer and Head of Corporate Development)in

Co-investors5AM VenturesOrbiMedPfizer Venture InvestmentsRoche Venture FundARCH Venture PartnersBay City Capital+1 more

GH Researchghres.comNASDAQ: GHRS

A pharmaceutical company whose executive team emphasizes innovation and patient care.

BiotechDigital HealthMental Health

Co-investorsForesite Capital

Hemab Therapeuticshemab.comin𝕏NASDAQ: COAG

Hemab develops targeted therapies for bleeding and clotting disorders such as Glanzmann thrombasthenia, Factor VII deficiency, Von Willebrand Disease, and heavy menstrual bleeding.

BiotechDigital HealthHealthtechMedical Devices

Co-investorsAccess BiotechnologyAvoro Capital AdvisorsHealthCapNovo HoldingsSofinnova PartnersAvoro Ventures

ImaraNASDAQ: ELVNMar 2019 · $63Macquired by Enliven Therapeutics · Feb 2023

Imara is a clinical-stage biopharmaceutical company developing small molecule therapeutics for unmet medical needs, currently advancing ELVN-001, a selective kinase inhibitor designed to treat chronic myeloid leukemia by targeting the BCR-ABL gene fusion.

BiotechCambridge, US

James G. McArthur(Executive Officer, Director)Christoph M. Adams(Executive Officer, Director)Richard Fair(President, Chief Executive Officer, Director)

BoardSara Nayeem(Director)Barbara Dalton(Director)David Mott(Director)

Co-investorsBay City CapitalNew Enterprise Associates (NEA)AlexandriaArix BioscienceLundbeckfonden VenturesOrbiMed+2 more

Invivydinvivyd.comin𝕏NASDAQ: IVVDSeries C · Apr 2021 · $340M

Invivyd develops monoclonal antibody medicines for the prevention and treatment of serious viral infectious diseases, starting with COVID-19 and other high-need indications.

BiotechHealthtech

Marc Elia(Founder)in

Co-investorsBain Capital Life SciencesForesite CapitalMRL Ventures FundPremji InvestGV (Google Ventures)MITHRIL+3 more

KALA BIOkalarx.cominNASDAQ: KALA

A biopharmaceutical company developing an artificial intelligence infrastructure platform designed for on-premises deployment in biotechnology and pharmaceutical research environments, serving biotech firms and pharma companies seeking secure access to advanced AI capabilities while retaining control over proprietary biological data; the company is also evaluating strategic alternatives for its legacy mesenchymal stem cell secretome assets after discontinuing its lead rare eye disease therapeutic program.

BiotechArlington, US

Justin Hanes(Director)inKevin Pojasek(Executive Officer)inDarius Kharabi(Executive Officer)inTodd Bazemore(Executive Officer)inMark Iwicki(Executive Officer, Director)inMary Reumuth(Executive Officer)in

Co-investorsLongitude CapitalSR One Capital ManagementYsios CapitalAtlas VentureLux CapitalThird Rock Ventures

Monopar Therapeuticsmonopartx.comNASDAQ: MNPRDec 2024 · $40M

Monopar Therapeutics is a clinical-stage biotechnology company developing radiopharmaceuticals for oncology imaging and treatment of advanced solid tumors, along with ALXN1840, a late-stage investigational treatment for Wilson Disease, a rare genetic disorder.

BiotechHealthtechMedical DevicesLake Forest, US

Chandler D. Robinson(Executive Officer, Director, Promoter)inChristopher M. Starr(Executive Officer, Director)Andrew P. Mazar(Executive Officer, Director)

BoardMichael J. Brown(Director)

Co-investorsJanus Henderson Investors

Nateranatera.comin𝕏NASDAQ: NTRA

Natera develops genetic tests and diagnostics using cell-free DNA technology to detect diseases including cancers, genetic disorders, and transplant-related conditions.

BiotechDigital HealthHealthtechMedical Devices

Matthew Rabinowitz(Co-founder & Executive Chairman)inJonathan Sheena(Founder)inSteven Chapman(Chief Executive Officer & President)

Co-investorsBain Capital Life SciencesCheyenne VenturesClaremont Creek VenturesForesite CapitalHarmony PartnersLightspeed Venture Partners+2 more

Nkarta, Inc.nkartatx.cominNASDAQ: NKTXAug 2019

Nkarta is a biotech company developing allogeneic CAR NK cell therapies for autoimmune diseases, aiming to offer safer and more accessible alternatives to autologous CAR-T treatments.

BiotechHealthtechSouth San Francisco, US

Paul Hastings(Executive Officer, Director)inPaul H.inMatthew Plunkett(Executive Officer)inPaul J. Hastings(Chief Executive Officer)in

BoardMichael Dybbs(Director)Jill Carroll(Director)in

Co-investorsNew Enterprise Associates (NEA)Samsara BioCapitalSR One Capital ManagementAmgen VenturesLogosNorwest Venture Partners+1 more

Olemaolema.comin𝕏NASDAQ: OLMA

Olema is a clinical-stage biopharmaceutical company developing novel therapies for metastatic breast cancer and other endocrine-driven cancers, targeting nuclear receptors and mechanisms of acquired resistance.

BiotechHealthtechSan Francisco, US

Cyrus L. Harmon, Ph.D.(Director)Cyrus Harmon(Executive Officer, Director)inCyrus L. Harmon(Director)inDavid C. Myles, Ph.D.(Executive Officer)Sean Bohen, M.D., Ph.D.(Executive Officer, Director)Naseem Zojwalla, M.D.(Executive Officer)in

Co-investorsAvoro Capital AdvisorsBain Capital Life SciencesForesite CapitalLightspeed Venture PartnersBiotechnology Value FundLogos+1 more

Parabilis Medicinesparabilismed.cominNASDAQ: PBLSJan 2026 · $305M

Helicons develops a peptide-based therapeutic platform designed to target intracellular proteins previously considered undruggable by combining the specificity of antibodies with the cell-penetrating properties of small molecules.

AI & Machine LearningBiotechDeep TechMedical Devices

Mathai Mammen(CEO, President and Chairman)in

Co-investorsARCH Venture PartnersCatalio Capital Management, LPForesite CapitalFrazier Life SciencesGeneral CatalystNextech Invest+7 more

PepGenpepgen.comin𝕏NASDAQ: PEPG

PepGen is a clinical-stage biotech company developing oligonucleotide therapies for neuromuscular and neurological diseases using its Enhanced Delivery Oligonucleotide (EDO) platform to improve tissue penetration and uptake in muscle tissues.

AI & Machine LearningBiotechHealthtechMedical DevicesBoston, US

James McArthur(Executive Officer, Director)inNoel P. Donnelly(Chief Financial Officer)inJoseph D. Vittiglio(Chief Business & Legal Officer and Secretary)inKasra Kasraian(Chief Technical Officer)in

BoardRamin Farzaneh-Far(Director)inJoshua Resnick(Director)

Co-investorsOxford Science Enterprises

Precision BioSciencesprecisionbiosciences.comin𝕏NASDAQ: DTIL

Precision BioSciences develops gene-editing medicines using its proprietary ARCUS genome editing platform, which employs sequence-specific nuclease enzymes to insert, remove, or repair DNA in living cells to treat hard-to-treat conditions including rare genetic diseases and hepatitis B (HBV).

BiotechDeep TechHealthtechDurham, US

DEREK JANTZ(Executive Officer, Director)inMATTHEW KANE(Executive Officer, Director)Jeff Smith(Co-founder)inDerek Jantz(Co-founder)inTODD MELBY(Executive Officer)inMichael Amoroso(President, Chief Executive Officer)in

Co-investorsage1Agent CapitalAliment CapitalBrace PharmaF-Prime CapitalOCV Partners+4 more

Protagonist Therapeuticsprotagonist-inc.comin𝕏NASDAQ: PTGXJul 2015

Protagonist is a company that emphasizes a diverse and inclusive corporate culture as central to its innovation, with stated goals of creating wins for its organization and for patients.

BiotechHealthtechMilpitas, US

Dinesh V. Patel, PhD(Executive Officer, Director)Dinesh Patel(President & Chief Executive Officer)

BoardAsish K. Xavier, Ph.D.(Director)Michael Panaccio, Ph.D.(Director)Armen Shanafelt, Ph.D.(Director)Paul F. Truex(Director)

Co-investorsAisling CapitalCanaan PartnersJJDCJohnson & Johnson Innovation – JJDCLilly VenturesStarfish Ventures

Prothenaprothena.comin𝕏NASDAQ: PRTAMar 2018

Prothena is a clinical-stage biotechnology company developing investigational therapies for neurodegenerative and rare peripheral amyloid diseases by targeting misfolded proteins.

BiotechDun Laoghaire, Co. Dublin, US

Tran B. Nguyen(Executive Officer)Arthur W. Homan(Executive Officer)Karin L. Walker(Executive Officer)inTara Nickerson, Ph.D.(Executive Officer)Wagner M. Zago, Ph.D.(Executive Officer)Carol D. Karp(Executive Officer)in

Co-investorsSofinnova VenturesInvescoWellington Management

Pyxis OncologyNASDAQ: PYXS

Pyxis Oncology is a clinical-stage biotech company developing antibody-drug conjugates for solid tumors, with its lead candidate targeting a fibronectin variant found in tumor tissue but not healthy tissue.

HealthtechBoston, US

Thomas Civik(Interim Chief Executive Officer, Director)

BoardDavid Steinberg(Executive Officer, Director)inChristoph Westphal(Director)Geeta Vemuri(Director)inJak Knowles(Director)John Flavin(Director)

Co-investorsAgent CapitalLongwood FundRTW Investments L.P.

Rani Therapeuticsranitherapeutics.cominNASDAQ: RANI

Rani Therapeutics develops oral drug delivery technology using robotic capsules to replace injectable biotherapeutics, addressing the challenge of delivering biologics through the gastrointestinal tract without needles.

BiotechDigital HealthHealthtechMedical DevicesSan Jose, US

Mir Hashim(Executive Officer, Director)inTalat Imran(Chief Executive Officer)in

BoardMir Imran(Founder)Andrew Farquharson(Director)in

Co-investorsInCube VenturesVHM

Rani Therapeutics HoldingsNASDAQ: RANIOct 2025

Rani Therapeutics is a clinical-stage biopharmaceutical company developing oral delivery technologies for biologics and drugs, primarily through its proprietary RaniPill capsule platform, which comes in two configurations (RaniPill GO for up to 3 mg microtablet doses and RaniPill HC for up to 200µL liquid doses).

BiotechSan Jose, US

Talat Imran(Executive Officer, Director)inSvai Sanford(Executive Officer)inMir Hashim(Executive Officer)in

BoardAbraham Bassan(Director)Vasudev Bailey, M.D.(Director)Mir Imran(Director)

Co-investorsInCube Ventures

Relmada Therapeuticsrelmada.comNASDAQ: RLMDMar 2026 · $160M

Relmada is a clinical-stage biopharmaceutical company developing therapies including NDV-01, a sustained-release intravesical formulation of gemcitabine and docetaxel for non-muscle invasive bladder cancer, and Sepranolone, a candidate targeting compulsive behaviors via GABAA receptor modulation.

BiotechHealthtechNew York, US

Sergio Traversa(Executive Officer, Director)Paul Kelly(Director)Maged Shenouda(Director)inEliseo O. Salinas(President and Chief Scientific Officer)inDouglas Beck(Chief Financial Officer)Charles Ence(Chief Accounting and Compliance Officer)

Co-investorsBioAdvanceBAM ElevateBraidwellCommodore CapitalJanus Henderson InvestorsOrbiMed+2 more

Rxsightrxsight.comin𝕏NASDAQ: RXST

RxSight develops the Light Adjustable Lens (LAL), an FDA-approved intraocular lens that surgeons can adjust after cataract surgery to fine-tune a patient's prescription once the eye has healed.

HealthtechMedical DevicesPasadena, US

Robert H. Grubbs(Director)Daniel M. Schwartz(Director)D. Verne Sharma(Executive Officer, Director)Richard Drinkward(Executive Officer)inRon Kurtz(President, Chief Executive Officer & Director)Mark Wilterding(Chief Financial Officer)in

Co-investorsFlying L PartnersForesite CapitalH.I.G. CapitalH.I.G. HealthBridge PartnersLongitude CapitalVisionary Ventures+2 more

Scribe Therapeuticsscribetx.comin𝕏NASDAQ: SCTXMar 2021

Scribe is a molecular engineering company developing CRISPR-based genetic therapies to treat cardiometabolic disease and other conditions.

BiotechDeep TechHealthtechMedical DevicesBerkeley, US

Benjamin Oakes(Founder & CEO)inJennifer A. Doudna, PhD(Co-founder, Scientific Advisor)Benjamin L. Oakes, PhD(Co-founder, President and CEO)David F. Savage, PhD(Co-founder, Scientific Advisor)Brett Staahl, PhD(Co-founder, VP of External Innovation)

BoardVijay Pande(Director)in

Co-investorsAndreessen HorowitzOrbiMedAvoro Capital AdvisorsMenlo VenturesAvoro Ventures

Scynexisscynexis.comin𝕏NASDAQ: SCYX

SCYNEXIS develops fungerp-based antifungal therapies, including SCY-247, for treating and preventing severe, progressive, and often fatal fungal diseases and antimicrobial-resistant infections.

BiotechDurham, US

Yves J. Ribeill(Executive Officer, Director)inCharles F. Osborne, Jr.(Executive Officer)Brian Schwab(Executive Officer)inDavid Angulo(Chief Executive Officer, President and Director)in

BoardLaurent Arthaud(Director)Mounia Chaoui(Director)

Co-investorsDecheng CapitalForesite CapitalDeerfield Management Company

Seres Therapeuticsserestherapeutics.comin𝕏NASDAQ: MCRB

Seres Therapeutics is a clinical-stage biotechnology company developing therapies composed of rationally selected live bacterial consortia to treat serious diseases through modulation of the human microbiome.

BiotechDigital HealthHealthtechMedical DevicesCambridge, US

Matthew Henn(President and Chief Scientific Officer)inJohn Aunins(Executive Officer)inEric D. Shaff(Executive Officer)inDavid Cook(Executive Officer)inRoger J. Pomerantz(Executive Officer, Director)inRichard N. Kender(Executive Chair and Interim Chief Executive Officer)

Co-investorsFlagship PioneeringSofinnova VenturesFidelity Investments

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

ADRxAerovate TherapeuticsAntera TherapeuticsCalimmuneConvergent TherapeuticsDiCE Molecules HoldingsFreenome HoldingsLantos TechnologiesLonestar MedicinesMemento MedicinesNanoMosaicNature's ToolboxSojournixSolstice OncologySuperluminal MedicinesTypewriter TherapeuticsVaxess Technologies, Inc.89BioAavantiBioAcumen PharmaceuticalsAdagio TxAlchemabAliada TherapeuticsAmbros TherapeuticsAmplifier TherapeuticsAperion LabsArtiosAset TherapeuticsAveXisBellicum PharmaceuticalsBraeburn PharmaceuticalscAMPfield TherapeuticsCanbridge PharmaceuticalsCarmot TherapeuticsCerebral TherapeuticsClementiaClementiapharmaCoherusCollegiumConvergent TxConveyor TherapeuticsCortica CareCorxelCytekDay OneDiagonal TherapeuticsDiceDicernaDimensionEdgewiseEidos TherapeuticsElektrofi

Browse all 353 investments with full details →

153 more tracked companies

Element BiosciencesEmergence TherapeuticsEmpaticaEnara BioEverest MedicinesEvodia BioEvodiaBioExpansion TherapeuticsExpedition TherapeuticsEyconisFamiliarmachinesFarcastForge BiologicsFormaForward TherapeuticsFrontier MedicinesGaleraGametoGentiBioGIVAXGlobal Blood TherapeuticsHaldaHalda TherapeuticsHemaBHilleVaxIDRxIDRXILiAD BiotechnologiesImbriaImbria PharmaceuticalsInfinimmuneInflaRxInhibikase TherapeuticsInhibrxInnoventricInozymeInterius BioInterius BioTherapeuticsIO BiotechiTeos TherapeuticsIvantis IncJanuxJnana TherapeuticsJunoKalvistaKaryopharmKinnateKinnate BiopharmaKolomaLegend BioLenzLifeMineLumenaLusaris TherapeuticsLyraMagenta MedicalMarianaMariana OncologyMBXMementoMerusMetagenomiMetseraMineralysMMI MicroModernaNapiGenNavaNavigator MedicinesNew Equilibrium BiosciencesNexCureNextopNiKang TherapeuticsNimbusNimbusNimbus TherapeuticsNivalisNorthLinks BioNucleixObsidian TherapeuticsOcelot BioOllinOncologyOptivoltOrchardPAhR TherapeuticsPandionPelotonPharmaPhathomPinnacle MedicinesPlantiblePluton BioPMV PharmaPoint BiopharmaPoplar TherapeuticsPrevailPrevail TherapeuticsProfound BioProtagonistQuellis BiosciencesRa PharmaceuticalsRadenceReframe SystemsRivus PharmaSatsumaSatsuma PharmaceuticalsSeagenSecretome TherapeuticsSeLux Diagnostics, Inc.Serapha BioShockwaveSidera BioSierra OncologySilverback TherapeuticsSlate MedicinesSomatusSortera TechnologiesSparrow PharmaStar TherapeuticsStokeStylus MedicineSummation BioSuperluminalSynapticureSynthegoSynthekineSynthorxT-KnifeT2 BiosystemsTaris BiomedicalTassoTenayaTeraPore TechnologiesTerremotobioterrestrialThriveworksTopl (Now Plasma)Torl BioTrace NeuroscienceTscanTScan TherapeuticsTyraVentusVentus TherapeuticsVerdiva BioVerve TherapeuticsViaCyteVitriVaxVividionWhiteSwellWindwardWindward Bio

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

Exits · 102

67 IPOs · 35 acquisitions · showing 79

FreenomeNASDAQ: FRNMSionnatxNASDAQ: SIONMineralys TherapeuticsNASDAQ: MLYSSpero TherapeuticsNASDAQ: SPROWave Life SciencesNASDAQ: WVEAclaris TherapeuticsNASDAQ: ACRSAdagio MedicalNASDAQ: ADGMAdagio Medical HoldingsNASDAQ: ADGMAdagio TherapeuticsNASDAQ: IVVDAeglea BiotherapeuticsNASDAQ: SYREAgenusNASDAQ: AGENAktis OncologyNASDAQ: AKTSAN2 TherapeuticsNASDAQ: ANTXApogee TherapeuticsNASDAQ: APGEArcutisNASDAQ: ARQTArvinas Holding Co. LLCNASDAQ: ARVNAtea PharmaceuticalsNASDAQ: AVIRBicara TherapeuticsNASDAQ: BCAXBioAge LabsNASDAQ: BIOABiohavenNYSE: BHVNBlack Diamond Therapeutics, IncNASDAQ: BDTXBolt BiotherapeuticsNASDAQ: BOLTBoundless BioNASDAQ: BOLDC4 TherapeuticsNASDAQ: CCCCCentury Therapeutics, Inc.NASDAQ: IPSCCeribellNASDAQ: CBLLCG OncologyNASDAQ: CGONClimbbioNASDAQ: CLYMCollegium PharmaceuticalNASDAQ: COLLConnect BiopharmaNASDAQ: CNTBCrineticsNASDAQ: CRNXCytek BiosciencesNASDAQ: CTKBDamora TherapeuticsNASDAQ: DMRADesigntxNASDAQ: DSGNDiffusion PharmaceuticalsNASDAQ: CRVODyne TherapeuticsNASDAQ: DYNEliem TherapeuticsNASDAQ: CLYMEnliven TherapeuticsNASDAQ: ELVNGH ResearchNASDAQ: GHRSHemab TherapeuticsNASDAQ: COAGImaraNASDAQ: ELVNInvivydNASDAQ: IVVDKALA BIONASDAQ: KALAMonopar TherapeuticsNASDAQ: MNPRNateraNASDAQ: NTRANkarta, Inc.NASDAQ: NKTXOlemaNASDAQ: OLMAParabilis MedicinesNASDAQ: PBLSPepGenNASDAQ: PEPGPrecision BioSciencesNASDAQ: DTILProtagonist TherapeuticsNASDAQ: PTGXProthenaNASDAQ: PRTAPyxis OncologyNASDAQ: PYXSRani TherapeuticsNASDAQ: RANIRani Therapeutics HoldingsNASDAQ: RANIRelmada TherapeuticsNASDAQ: RLMDRxsightNASDAQ: RXSTScribe TherapeuticsNASDAQ: SCTXScynexisNASDAQ: SCYXSeres TherapeuticsNASDAQ: MCRBSolid BiosciencesNASDAQ: SLDBSpyglass PharmaNASDAQ: SGPSutroVaxNASDAQ: PCVXTYRA BiosciencesNASDAQ: TYRAVaxcyteNASDAQ: PCVXVor BiopharmaNASDAQ: VORXilio TherapeuticsNASDAQ: XLOAerovate Therapeuticsacq. by Jade BiosciencesCalimmuneacq. by CSL Behring89Bioacq. by RocheAliada Therapeuticsacq. by AbbVieAmbros Therapeuticsacq. by Werewolf TherapeuticsBellicum Pharmaceuticalsacq. by The University of Texas MD Anderson Cancer CenterBluejay Therapeuticsacq. by Mirum PharmaceuticalsDay Oneacq. by ServierDicernaacq. by Novo NordiskDTx Pharmaacq. by NovartisEidos Therapeuticsacq. by BridgeBio PharmaElektrofiacq. by Halozyme Therapeutics

Portfolio news

latest coverage across their companies

IPO stake values · per SEC filings · 25

Value of this firm's stake in each portfolio company at its IPO price, from the prospectus principal-stockholder table.

CompanyOwnedIPO priceAt IPOStake value
Sionnatx21.9%$18.00Feb 2025$167.8M
Climbbio51.9%$12.50Aug 2021$164.4M
Eliem Therapeutics51.9%$12.50Aug 2021$164.4M
Parabilis Medicines6.5%$20.00Jun 2026$154.9M
Vor Biopharma22.2%$18.00Feb 2021$142.2M
Apogee Therapeutics3.4%$62.00Mar 2024$122.6M
Cytek Biosciences5.1%$17.00Jul 2021$113.2M
TYRA Biosciences14.6%$16.00Sep 2021$95.8M
Bicara Therapeutics9.9%$18.00Sep 2024$92.2M
Hemab Therapeutics10.9%$18.00May 2026$87.1M
Wave Life Sciences24.9%$16.00Nov 2015$83.4M
Adagio Therapeutics4.4%$17.00Aug 2021$81.6M
Invivyd4.4%$17.00Aug 2021$81.6M
Dyne Therapeutics5.5%$28.00Jan 2021$78.5M
Spyglass Pharma13.6%$16.00Feb 2026$69.3M
AN2 Therapeutics19.6%$15.00Mar 2022$55M
Vaxcyte6.2%$16.00Jun 2020$47.8M
SutroVax6.2%$16.00Jun 2020$47.8M
Bolt Biotherapeutics6.9%$20.00Feb 2021$47.6M
Solid Biosciences7.8%$16.00Jan 2018$43M
Prothena7.8%$22.00Oct 2013$36.3M
Olema4.5%$19.00Nov 2020$32.8M
Collegium Pharmaceutical6.6%$20.00Jan 2016$30.9M
Mineralys Therapeutics4.9%$16.00Feb 2023$30.9M
Black Diamond Therapeutics, Inc4.6%$19.00Jan 2020$30.2M

Source: SEC S-1 / 424B prospectus filings. Stake value = shares beneficially owned × the initial public offering price, as disclosed — a market value at IPO, not a return multiple (the firm's original cost is not disclosed).

Public market activity · per SEC filings

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SC 13D/A filingSC 13D/A

Disclosed stake · filed Dec 2018

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SC 13G/A filingSC 13G/A

Disclosed stake · filed Feb 2017

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Disclosed stake · filed Feb 2017

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Disclosed stake · filed Feb 2017

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Disclosed stake · filed Feb 2017

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Disclosed stake · filed Feb 2017

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Disclosed stake · filed Feb 2017

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Disclosed stake · filed Feb 2017

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Disclosed stake · filed Feb 2017

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450 insider ownership filings (Forms 3/4/5)

at Septerna, Inc. (SEPN), Inhibikase Therapeutics, Inc. (IKT), Artiva Biotherapeutics, Inc. (ARTV), Freenome, Inc. (FRNM), Parabilis Medicines, Inc. (PBLS), Vor Biopharma Inc. (VOR), Climb Bio, Inc. (CLYM), ARS Pharmaceuticals, Inc. (SPRY)

From the firm's own SEC EDGAR filings — stakes and insider roles in public companies, typically portfolio companies after an IPO. Not a portfolio list published by the firm.

Frequently asked questions

How many investments has RA Capital made?
RA Capital has 353 tracked investments, 102 of which have exited, including 53 dated in the last 24 months.
What stage does RA Capital invest at?
RA Capital invests at the Seed, Series A, Series B, Series C, Growth, Late Stage stages.
What sectors does RA Capital focus on?
RA Capital focuses on Biotech, Climate Tech, Digital Health, Healthtech, Medical Devices.
Where is RA Capital located?
RA Capital is headquartered in Boston, US.
Does RA Capital lead rounds?
RA Capital has led 24 of the 65 rounds where its role is on record.
Who does RA Capital co-invest with?
RA Capital most often shares deals with Foresite Capital, OrbiMed, Bain Capital Life Sciences, among 256 tracked co-investors.
What size deals does RA Capital back?
Across 27 deals with disclosed amounts, RA Capital has joined rounds of $7.9M – $325M (median $100M).

Media · Podcasts & interviews

featuring the team

The Investor's Paradox with Peter Kolchinsky, RA Capital

Incubate Coalition · Peter Kolchinsky

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Co-investors · 71

Bain Capital Life Sciences

Bain Capital Life Sciences, founded in 2016, invests in biopharmaceutical, medical device, diagnostic, and life science tool companies globally, focusing on companies addressing unmet medical needs and driving medical innovation.

Vivo Capital

Vivo Capital is a global healthcare-focused investment firm operating a multi-strategy platform spanning venture capital, private equity, and public equity. It aims to expand healthcare access and drive innovation through its 'Ecosystem Strategy.'

$10M – $50M
Atlas Venture

Atlas Venture is a life sciences venture capital firm with three decades of experience investing in and building biotech and medical innovation companies, including startups launched from its own incubator.

$500K – $1M
Samsara BioCapital

Samsara BioCapital is an investment firm backing the development of transformative therapeutics for patients, bringing together scientists, physicians, drug developers, and business leaders to support next-generation therapeutic breakthroughs.

Andreessen Horowitz

Andreessen Horowitz (a16z) is a venture capital firm founded in 2009 by Marc Andreessen and Ben Horowitz, known for pioneering the platform model with a large team of operators supporting founders across stages.

$500K – $50M
GV (Google Ventures)

GV (Google Ventures) is a venture capital firm that has invested in artificial intelligence and machine learning since its early days, building a global portfolio of more than 100 AI companies across infrastructure, life sciences, and applications.

$250K – $50M
New Enterprise Associates (NEA)

New Enterprise Associates (NEA) is a venture capital firm that invests in and provides long-term support to founders building new companies.

$200K – $40M
Sanofi Ventures

Sanofi Ventures is the corporate venture capital arm of Sanofi, investing in early-stage biotech and digital health companies focused on improving human health. It serves as Sanofi's entry point into the innovation ecosystem.

$5M
Pfizer Venture Investments

Pfizer Venture Investments is a strategic venture fund that doesn't require product or technology rights as a condition of investing, giving founders independence while still aiming for future collaboration with Pfizer, and its team blends venture investing with business development and drug discovery expertise to back frontier scientific bets—such as neuroscience, in-vivo cell engineering, dark-genome target discovery, and the blockchain-based longevity accelerator VitaDAO—that many biotech investors avoid. The fund also runs an active China strategy through a locally based venture vehicle and direct investments like OTR Therapeutics, and it has become a channel for strategic deals, with portfolio companies acquired by AbbVie, Ipsen, and Gilead/Kite.

Both backed · 12
$5M – $20M
59 more co-investors

Canaan PartnersForbion5AM VenturesSV Health InvestorsVersant VenturesThird Rock VenturesPivotal Life SciencesAisling CapitalRTW Investments L.P.F-Prime CapitalVenrockSR One Capital ManagementARCH Venture PartnersvenBio PartnersMRL Ventures FundPolaris PartnersAndera PartnersMPM BioImpactThe Column GroupNovartis Venture FundRed Tree VentureInsight PartnersArtis VenturesEQT Life SciencesJohnson & Johnson Innovation – JJDCRoche Venture FundGeneral CatalystKleiner PerkinsNew Leaf Venture PartnersAnzu PartnersVertex Ventures HCUS Venture PartnersMithril Capital ManagementAccess IndustriesHatteras Venture PartnersYsios CapitalQiming Venture PartnersHealthCapHumboldtCoatue ManagementSignalFireTwo Sigma Ventures23andMeBaruch Future VenturesPlayground GlobalOmega FundsMedical Excellence CapitalPsyMed VenturesAbbVieDe Novo VenturesNegev CapitalOverwater Ventures LlcUnknown VenturesAtomicoXtripe AngelsXSeed CapitalTencent HoldingsCofounders CapitalQiming Venture Partners USA

Firms observed investing alongside RA Capital, from public investor directories. Shared companies are the overlap with RA Capital's recorded portfolio.

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