Fundraising Fox

RA Capital

Crossover fundActively deploying

Boston · Seed–Late Stage · 82 people tracked

Also known as RA CAPITAL MANAGEMENT, LP · RA Capital Nexus · RA Capital Nexus International · RA Capital Planetary Health · RA Capital Planetary Health International

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Investment thesis

RA Capital pursues evidence-based, full-lifecycle investing across healthcare, life sciences, and planetary health. It provides multi-stage capital spanning private and public markets, from new company creation and seed-stage incubation through venture rounds, crossover financing, IPO, and later-stage public investing. The firm emphasizes deep landscape research, scientific diligence, and operational company-building support, backed by a team of over 200 people with scientific and operational depth. In healthcare it partners early to shape strategy and define proof points, then provides capital continuity through growth. Its planetary health arm targets near-market, scalable companies advancing resource availability, energy innovation, and industrial productivity. Its Raven platform incubates and co-creates companies to address unmet biomedical needs.

Source: firm website, verified Aug 27, 2026.

Stage
Seed–Late Stage
HQ
Boston, Massachusetts, US
Instruments
Equity
Founded
2004
Last 12 months
24 investments
AUM
$16.4B
Tracked investments
306

Team · 82 people

from the firm's website & curated & public directories
Brigid O’Brien· Managing Partner
Adam Kaye· Senior Managing Director and Partner, Structured Capitalin
Jeremy Lack· Partner
Matt Hammond· Partnerin
Emory Werner· Investment Director, Venturein
Jonathan Pritz· Investment Director, Venturein
Kathryn Meng· Principalin
Laura Tadvalkar· Managing Director, Venturein
Megan Lipcsey· Investment Director
Tess Cameron· Managing Director, Venturein
Adrian Bot· Venture Partner
Anish Suri· Consulting Venture Partner
Bimal Shah· Venture Partner
David Weinstock· Venture Partner
Fanny Cavalié· Venture Partner
Gerald Sewack· Venture Partnerin
Jacob Oppenheim· Venture Partner
Jill Wykosky· Venture Partnerin
Milind Deshpande· Venture Partner
Nithya Desikan· Venture Partner
Paul Rothman· Venture Partner
Robert Nicol· Venture Partner
Abigail Schmitz· Senior Associate, Corporate Developmentin
Albert Kim· Advisor
Alex Miller· Senior Associate, Venturein
Alex Zhang· Vice President, Structured Capitalin
Alison Tisdale· Advisor
Dan Grau· Advisor
David Feltquate· Advisorin
Eric Wei· Associate, Structured Capitalin
Henry Stusnick· Analystin
Jaclyn Henderson· Advisorin
Joel Barrish· Advisor
Julie Gupta· Senior Associate, Corporate Development, Venturein
Justin Waney· Vice President, Structured Capitalin
Kurt Armbrust· Entrepreneur in Residence
Matt Stanton· Advisor
Michael Sherman· Advisor
Mike Cloonan· Advisor
Neil Buckley· Advisor
Pat Schnettler· Senior Associatein
Patrick Trojer· Advisor
Prithviraj Singha Roy· Analystin
Richard Xie· Senior Health Economistin
Sadik Kassim· Advisor
Sophie Papa· Advisor
Tyler Carney· Associate, Structured Capitalin

Founder mafia

4 people who came through RA Capital went on to found or lead other companies.

What they invest in

from 186 of 306 portfolio companies

Biotech ×157Healthtech ×97Medical Devices ×73Deep Tech ×22Digital Health ×21AI & Machine Learning ×16Climate Tech ×5Enterprise Software ×5

HQs:United States×138United Kingdom×4Switzerland×2China×2Canada×1Colombia×1

Who they back

founder profiles across 83 portfolio companies
46%
solo founders
38 of 83 mapped founding teams
30%
repeat founders
of 30 founders with career history
~4 yrs
old at investment
median across 39 dated deals

Founding team size:solo founder×382 founders×253 founders×144+ founders×6

Where their founders studiedfrom 22 founders with education data

Massachusetts Institute of Technology ×5Harvard Business School ×3Harvard University ×2MIT Sloan School of Management ×2University of California, Berkeley ×2

Where their founders worked beforefrom 30 founders with career history

MPM BioImpact ×4Johnson & Johnson ×3Genentech ×2Maverick Therapeutics ×2Potenza Therapeutics ×2Stanford University ×2Trieza Therapeutics ×2University of California, Berkeley ×2

Accelerator rootsportfolio companies that came through a program

Y Combinator ×2

12 founders hold a PhD · 6 hold an MBA (of 26 with degree data)

Investments · 306 tracked

founders shown can be your intro path

By year:2026 · 192025 · 162024 · 112023 · 72022 · 42021 · 92020 · 52019 · 32018 · 22017 · 22016 · 32015 · 690 dated

Freenomefreenome.comin𝕏NASDAQ: FRNMOct 2015✓ verified

Freenome develops early-stage cancer detection technology using blood tests to identify cancer in its earliest, most treatable phases.

AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesLondon

Riley Ennis(Co-Founder and Chief Product Officer)Charles Roberts(Director)inGabriel Otte(Director)in

BoardStuart Lawson(Director)

Co-investorsAME Cloud VenturesAndreessen HorowitzArtis VenturesAsset Management CompanyAverin CapitalBain Capital Life Sciences+8 more

Mineralys Therapeuticsmineralystx.comin𝕏NASDAQ: MLYSJun 2022SEC filingmedium confidence

Mineralys Therapeutics is a clinical-stage pharmaceutical company developing lorundrostat, a treatment targeting dysregulated aldosterone.

BiotechHealthtechRadnor, US

Eric Warren(Chief Commercial Officer)inAlex Gold(Chief Medical Officer)Adam Levy(Executive Officer)Alexander Asam(Director)

BoardBrian Taylor Slingsby(Founder & former CEO / Board Director)Olivier Litzka(Director)in

Board seatDerek DiRocco· per SEC Form D · $118M raise · filed Jun 2022

Co-investorsAndera PartnersSamsara BioCapitalSR One Capital ManagementYsios CapitalBoulder VenturesCatalys Pacific

Spero Therapeuticssperotherapeutics.cominNASDAQ: SPROMar 2017

Spero Therapeutics is a clinical-stage biopharmaceutical company developing medicines for immune-mediated diseases, led by SP001, a third-generation anti-CD40L antibody targeting IgG4-related disease.

BiotechCambridge, US

Ankit Mahadevia(Executive Officer, Director)inStephen Garbacz(Executive Officer)in

BoardJean-Francois Formela(Director)inCasper Breum(Director)Vikas Goyal(Director)

Board seatReza Halse· per SEC Form D

Co-investorsHEALTHCARE ROYALTY PARTNERSMRL Ventures FundOUP (Osage University Partners)AlphabetAtlas Venture

Wave Life Scienceswavelifesciences.comin𝕏NASDAQ: WVEJan 2015

Wave Life Sciences develops RNA-targeting therapeutics using RNA-editing modalities and chemistry to treat rare and common diseases, with a clinical pipeline addressing Alpha-1 antitrypsin deficiency, Duchenne muscular dystrophy, Huntington's disease, and obesity.

BiotechHealthtechLongevitySingapore

Takeshi Wada(Director)inGregory L. Verdine(Director)Paul B. Bolno, M.D.(Executive Officer, Director)in

BoardKen Takanashi(Director)Masaharu Tanaka(Director)

Board seatPeter Kolchinsky· per SEC Form D

Co-investorsForesite Capital

Aclaris Therapeuticsaclaristx.comNASDAQ: ACRS

Aclaris develops investigational monoclonal antibodies and small-molecule inhibitors targeting immune pathways for the treatment of atopic, autoimmune, and respiratory diseases.

BiotechHealthtechMedical DevicesWayne, US

Neal Walker(Executive Officer, Director)Kamil Ali-Jackson(Executive Officer)Stuart D. Shanler(Executive Officer)Joseph Monahan(Executive Officer)Hugh Davis(Executive Officer, Director)James Loerop(Executive Officer)

Co-investorsAisling CapitalAPERTURE Venture PartnersF-Prime CapitalForesite CapitalSofinnova VenturesSofinnova Venture Partners+1 more

Adagio Medicaladagiomedical.comNASDAQ: ADGM

HealthtechLaguna Hills, US

Olav Bergheim(Executive Officer, Director)Andrew Wade(Executive Officer)Hugh Neuharth(Executive Officer)

BoardMichael Zhao(Director)James Cox(Director)

Aeglea BiotherapeuticsinNASDAQ: SYRE

BiotechAustin, US

David G. Lowe(Executive Officer, Director)George Georgiou(Director)Charles N. York(Executive Officer)in

BoardHenry Skinner(Director)Armen Shanafelt(Director)

Agenusagenusbio.comNASDAQ: AGENAug 2026

BiotechHealthtechMedical DevicesLexington, US

Garo Armen(Executive Officer, Director)Ozer Baysal(Executive Officer)Robert Stein(Executive Officer)Christine Klaskin(Executive Officer)Karen Valentine(Executive Officer)

BoardBrian Corvese(Director)

Co-investorsAdvent Life SciencesGrazia Equity GmbHHEALTHCARE ROYALTY PARTNERSOberland CapitalCommodore CapitalInvus+1 more

Aktis Oncologyaktisoncology.cominNASDAQ: AKTSSep 2024 · $318M

Aktis Oncology discovers and develops targeted radiopharmaceuticals for treating solid tumors.

BiotechHealthtechMedical DevicesBoston, US

Todd Foley(Co-founder and Chairman)inPatrick Baeuerle(Co-founder & Advisor)inShulamit Ron-Bigger(Executive Officer)in

BoardHelen S. Kim(Director)Oleg Nodelman(Director)inAndrew Levin(Director)

Co-investorsAndreessen HorowitzEcoR1 CapitalMPM BioImpactMRL Ventures FundTCG CrossoverVida Ventures+2 more

AN2 Therapeuticsan2therapeutics.cominNASDAQ: ANTX

AN2 Therapeutics is a clinical-stage biopharmaceutical company developing small-molecule drugs from its boron chemistry platform, with a pipeline spanning hematologic diseases, infectious diseases, oncology, and bone disorders.

BiotechHealthtechMenlo Park, US

Joseph S. Zakrzewski(Co-Founder & Director)Eric Easom(Co-Founder, President & CEO)inGeorge H. Talbot(Co-Founder & Senior Clinical Advisor)Michael R.K. (Dickon) Alley(Co-Founder, SVP Research Fellow, Head of Biology)Sanjay Chanda(Chief Development Officer)inLucy O. Day(Chief Financial Officer)

Co-investorsAdjuvant CapitalBioRock VenturesFlucas VenturesMountain Group CapitalHatteras Venture Partners

Apogee Therapeuticsapogeetherapeutics.cominNASDAQ: APGE

Apogee Therapeutics develops engineered antibody therapies to treat inflammatory and immune diseases with reduced injection frequency compared to existing treatments.

BiotechHealthtechMedical Devices

Michael Hendersonin

Co-investorsAccess Biotechnology

Arcutis BiotherapeuticsNASDAQ: ARQTOct 2019

BiotechWestlake Village, US

Alexander Asam(Director)Ricky Sun(Director)Todd Franklin Watanabe(Executive Officer, Director)

BoardPatrick Heron(Director)inDaniel Estes(Director)inJonathan Silverstein(Director)

Co-investorsBain Capital Life SciencesFrazier Life Sciences

Arvinas Holding Co. LLCarvinas.comin𝕏NASDAQ: ARVN

Arvinas is a biopharmaceutical company developing PROTAC protein degrader therapies, with a pipeline focused on oncology and neurology.

BiotechHealthtechNew Haven, US

Sean Cassidy(Executive Officer)inManuel Litchman(Executive Officer, Director)in

BoardStephen Squinto(Director)inLiam Ratcliffe(Director)inTim Shannon(Director)inKush Parmar(Director)

Co-investors5AM VenturesAccess BiotechnologyCanaan PartnersConnecticut InnovationsNextech InvestSolasta Ventures+1 more

Atea Pharmaceuticalsateapharma.comNASDAQ: AVIR

Atea is a clinical-stage biopharmaceutical company developing oral direct-acting antiviral therapies for single-stranded RNA viruses, currently focused on a bemnifosbuvir and ruzasvir regimen in Phase 3 development for hepatitis C virus (HCV).

BiotechHealthtechBoston, US

Jean-Pierre Sommadossi, Ph.D.(Executive Officer, Director)

BoardBruno Lucidi(Director)Evgeny Zatsev(Director)Frank Yu(Director)Gerald Chan(Director)Bruce Polsky(Director)

Co-investorsBain Capital Life Sciences

BioAge Labsbioagelabs.comin𝕏NASDAQ: BIOAFeb 2024

BIOAGE develops therapies targeting the molecular pathways that drive aging to increase healthspan and address age-related chronic diseases.

BiotechHealthtechLongevityRichmond, US

Kristen Fortney, PhD(Co-Founder, CEO)Eric Morgen, MD(Co-Founder, COO)Kristen Fortney(Executive Officer, Director)inEric Morgen(Director)inDov Goldstein(Executive Officer)in

BoardPatrick Enright(Director)in

Co-investorsAndreessen HorowitzElad GilFelicis VenturesIA Seed VenturesLongitude CapitalOrbiMed+4 more

Biohavenbiohaven.comin𝕏NYSE: BHVN

Biohaven is a pharmaceutical company that discovers, develops, and commercializes medications for neurological and neuropsychiatric diseases, including epilepsy, pain, mood disorders, OCD, spinocerebellar ataxia, and spinal muscular atrophy.

BiotechHealthtechMedical DevicesConnecticut, US

Vlad Coric, M.D.(Chairman & Chief Executive Officer)

Co-investorsOberland CapitalSixth Street

Black Diamond TherapeuticsNASDAQ: BDTX

Co-investorsVersant Ventures

Bolt Biotherapeuticsboltbio.comin𝕏NASDAQ: BOLT

Bolt Biotherapeutics is a clinical-stage biotech company developing novel immunotherapies that leverage innate immune system mechanisms to treat cancer.

BiotechHealthtechMedical DevicesSan Francisco, US

Dr. Edgar G. Engleman(Founder)

Co-investorsPfizer Venture InvestmentsSamsara BioCapitalSofinnova VenturesVivo CapitalNan Fung Life SciencesNovo Holdings+1 more

Boundless Bioboundlessbio.comin𝕏NASDAQ: BOLD

Boundless Bio develops precision oncology medicines targeting ecDNA-amplified cancers, specifically creating a new category of ecDNA-directed therapies for patients with oncogenic alterations.

BiotechMedical DevicesLa Jolla, US

Zachary D. Hornby(Executive Officer, Director)in

BoardBenjamin Cravatt, Ph.D.(Director)Kristina Burow(Director)inCarolyn Ng, Ph.D.(Director)Jakob Loven, Ph.D.(Director)Ho Sung Cho, Ph.D.(Director)

Co-investorsARCH Venture PartnersNextech Invest

C4 Therapeuticsc4therapeutics.comin𝕏NASDAQ: CCCCDec 2015

C4 Therapeutics develops targeted protein degradation medicines aimed at treating disease.

BiotechCambridge, US

BoardMarc Cohen(Executive Officer, Director)Jason Fisherman(Executive Officer, Director)Miles Stuchin(Director)Bruce Downey(Director)Bihua Chen(Director)William M. Scalzulli(Director)

Co-investors3E Bioventures CapitalBain Capital Life SciencesNextech Invest

Century TherapeuticsNASDAQ: IPSC
Ceribellceribell.comin𝕏NASDAQ: CBLL

Ceribell is a medical technology company that develops products for detecting and monitoring seizures, including EEG-based diagnostic systems.

AI & Machine LearningDigital HealthHealthtechMedical DevicesSunnyvale, US

Josef Parvizi(Director)inXingjuan (Jane) Chao(President, CEO, Co-Founder & Director)inScott Blumberg(Executive Officer)inJoseph Taylor(Director)Raymond Woo(Executive Officer)David Stoffel(Executive Officer)

Co-investorsLongitude CapitalRed Tree VentureShangBay Capital LLC

CG Oncologycgoncology.comin𝕏NASDAQ: CGON

CG Oncology develops an investigational oncolytic immunotherapy for urologic cancer patients, specifically targeting BCG-unresponsive non-muscle invasive bladder cancer.

BiotechHealthtechMedical Devices

Co-investorsDecheng CapitalForesite CapitalLongitude CapitalPalm Drive CapitalTCG CrossoverACORN BIOVENTURES+2 more

ClimbbioNASDAQ: CLYM
Connect Biopharmaconnectbiopharma.cominNASDAQ: CNTB

Connect Biopharma is a clinical-stage biopharmaceutical company developing antibody-based therapies targeting inflammatory diseases such as atopic dermatitis and asthma.

BiotechHealthtechSan Diego, US

Co-investorsCo-Win Ventures

Design TherapeuticsNASDAQ: DSGN

Co-investorsSR One Capital Management

GH Researchghres.comNASDAQ: GHRS

A pharmaceutical company whose executive team emphasizes innovation and patient care.

BiotechDigital HealthMental Health

Co-investorsForesite Capital

ImaraNASDAQ: ELVN

BiotechCambridge, US

James G. McArthur(Executive Officer, Director)Christoph M. Adams(Executive Officer, Director)

BoardSara Nayeem(Director)Barbara Dalton(Director)David Mott(Director)Robert Hopfner(Director)

Co-investorsBay City CapitalNew Enterprise Associates (NEA)Arix BioscienceOrbiMed

Nateranatera.comin𝕏NASDAQ: NTRA

Natera develops genetic tests and diagnostics using cell-free DNA technology to detect diseases including cancers, genetic disorders, and transplant-related conditions.

BiotechDigital HealthHealthtechMedical Devices

Matthew Rabinowitz(Co-founder & Executive Chairman)Jonathan Sheena(Founder)in

Co-investorsBain Capital Life SciencesCheyenne VenturesClaremont Creek VenturesForesite CapitalHarmony PartnersLightspeed Venture Partners+1 more

nKartaNASDAQ: NKTX
Parabilis Medicinesparabilismed.cominNASDAQ: PBLSJan 2026 · $305M

Helicons develops a peptide-based therapeutic platform designed to target intracellular proteins previously considered undruggable by combining the specificity of antibodies with the cell-penetrating properties of small molecules.

AI & Machine LearningBiotechDeep TechMedical Devices

Mathai Mammen(CEO, President and Chairman)in

Co-investorsARCH Venture PartnersCatalio Capital Management, LPForesite CapitalFrazier Life SciencesGeneral CatalystNextech Invest+5 more

PepGenpepgen.comin𝕏NASDAQ: PEPG

PepGen is a clinical-stage biotech company developing oligonucleotide therapies for neuromuscular and neurological diseases using its Enhanced Delivery Oligonucleotide (EDO) platform to improve tissue penetration and uptake in muscle tissues.

AI & Machine LearningBiotechHealthtechMedical DevicesBoston, US

James McArthur(Executive Officer, Director)in

BoardRamin Farzaneh-Far(Director)Joshua Resnick(Director)Christopher Ashton(Director)Heidi Henson(Director)

Co-investorsOxford Science Enterprises

Precision BioSciencesprecisionbiosciences.comin𝕏NASDAQ: DTIL

Precision BioSciences develops gene-editing medicines using its proprietary ARCUS genome editing platform, which employs sequence-specific nuclease enzymes to insert, remove, or repair DNA in living cells to treat hard-to-treat conditions including rare genetic diseases and hepatitis B (HBV).

BiotechDeep TechHealthtechDurham, US

DEREK JANTZ(Executive Officer, Director)inMATTHEW KANE(Executive Officer, Director)Jeff Smith(Co-founder)inDerek Jantz(Co-founder)inTODD MELBY(Executive Officer)in

BoardROBERT ADELMAN(Director)

Co-investorsage1Aliment CapitalBrace PharmaF-Prime CapitalOCV PartnersOUP (Osage University Partners)+4 more

Pyxis OncologyNASDAQ: PYXS

HealthtechBoston, US

BoardDavid Steinberg(Executive Officer, Director)Christoph Westphal(Director)Geeta Vemuri(Director)Jak Knowles(Director)John Flavin(Director)Lucio Iannone(Director)

Co-investorsLongwood FundAgent Capital

Rani Therapeutics HoldingsNASDAQ: RANI

BiotechSan Jose, US

Talat Imran(Executive Officer, Director)Svai Sanford(Executive Officer)Mir Hashim(Executive Officer)

BoardAbraham Bassan(Director)Vasudev Bailey, M.D.(Director)Mir Imran(Director)

Co-investorsInCube Ventures

Rxsightrxsight.comin𝕏NASDAQ: RXST

RxSight develops the Light Adjustable Lens (LAL), an FDA-approved intraocular lens that surgeons can adjust after cataract surgery to fine-tune a patient's prescription once the eye has healed.

HealthtechMedical DevicesPasadena, US

Robert H. Grubbs(Director)Daniel M. Schwartz(Director)D. Verne Sharma(Executive Officer, Director)Richard Drinkward(Executive Officer)in

BoardJavier Perez-Sala(Director)Jan Bonel(Director)

Co-investorsFlying L PartnersForesite CapitalH.I.G. CapitalH.I.G. HealthBridge PartnersLongitude CapitalVisionary Ventures+1 more

Scribe Therapeuticsscribetx.comin𝕏NASDAQ: SCTXMar 2021

Scribe is a molecular engineering company developing CRISPR-based genetic therapies to treat cardiometabolic disease and other conditions.

BiotechDeep TechHealthtechMedical DevicesBerkeley, US

Benjamin Oakes(Founder & CEO)inJennifer A. Doudna, PhD(Co-founder, Scientific Advisor)Benjamin L. Oakes, PhD(Co-founder, President and CEO)David F. Savage, PhD(Co-founder, Scientific Advisor)Brett Staahl, PhD(Co-founder, VP of External Innovation)

BoardVijay Pande(Director)in

Co-investorsAndreessen HorowitzOrbiMedAvoro Capital AdvisorsMenlo VenturesAvoro Ventures

Seres Therapeuticsserestherapeutics.comin𝕏NASDAQ: MCRB

Seres Therapeutics is a clinical-stage biotechnology company developing therapies composed of rationally selected live bacterial consortia to treat serious diseases through modulation of the human microbiome.

BiotechDigital HealthHealthtechMedical DevicesCambridge, US

Matthew Henn(President and Chief Scientific Officer)

Co-investorsFlagship PioneeringSofinnova Ventures

Sionna TherapeuticsNASDAQ: SION
Solid Biosciencessolidbio.comin𝕏NASDAQ: SLDB

Solid Biosciences is a precision genetic medicine company developing a pipeline of gene therapy candidates for rare neuromuscular and cardiac diseases, including Duchenne muscular dystrophy, Friedreich's ataxia, CPVT, and TNNT2-mediated dilated cardiomyopathy.

BiotechHealthtechCharlestown, US

Stephen DiPalma(Executive Officer)Alexander (Bo) Cumbo(Executive Officer, Director)Carl Morris(Executive Officer)inMartin Freed(Director)Paul Herizch(Executive Officer)Robert Huffines(Director)

Co-investorsBain Capital Life SciencesForesite Capital

Spyglass Pharmaspyglasspharma.cominNASDAQ: SGP

SpyGlass Pharma develops a sustained drug delivery platform for treating chronic ophthalmic diseases such as glaucoma, integrating drugs, procedures, and devices for long-term disease control and vision preservation.

BiotechHealthtechMedical DevicesAliso Viejo, US

Glenn Sussman(Co-founder)inMalik Y. Kahook(Co-founder)inPatrick Mooney(CEO)

BoardJake Merrill(Director)Geoff Pardo(Director)Bilal Khan(Director)

Co-investorsNew Enterprise Associates (NEA)Samsara BioCapitalVensana Capital

Vaxcytevaxcyte.comNASDAQ: PCVX

Vaxcyte develops broad-spectrum vaccines to prevent bacterial infections, using a cell-free protein synthesis platform and synthetic chemistry techniques.

BiotechHealthtech

Grant Pickering(Founder)in

Co-investorsBioRock VenturesCTI Life Sciences Fund L.P.Foresite CapitalFrazier Life SciencesLongitude Capital

Vor BiopharmaNASDAQ: VOR

Co-investors5AM VenturesOUP (Osage University Partners)

Xilio Therapeuticsxiliotx.cominNASDAQ: XLO

Xilio Therapeutics is a clinical-stage biotechnology company developing masked immuno-oncology therapies that use protein engineering to remain inactive until activated by tumor-specific proteases within the tumor microenvironment.

BiotechHealthtechWaltham, US

Rene Russo(Executive Officer, Director)inJoseph Farmer(Executive Officer)Timothy Clackson(Executive Officer)Paul Clancy(Director)Daniel Curran(Director)Nancy Hong(Director)

Co-investorsBain Capital Life SciencesBay City CapitalF-Prime CapitalM VenturesMRL Ventures FundRiverVest Venture Partners+4 more

Bambusa Therapeuticsbambusatx.cominFeb 2025✓ verified

Bambusa Therapeutics develops bispecific antibodies for immunological and inflammatory (I&I) disorders, using antibody engineering to target multiple I&I indications.

BiotechHealthtechMedical DevicesAustin, US

Shanshan Xu(Founder & Chief Executive Officer)inHelmut Jeggle(Co-Founder)inThang Ho(Chief Development Officer)inCrystal MacKay(Chief Operating Officer)in

Board seatDerek DiRocco· per SEC Form D

Co-investorsINCE CapitalBiotechnology Value FundJanus Henderson InvestorsREDMILESalvia

Outpace Biooutpacebio.cominJul 2024✓ verified

Outpace Bio develops engineered protein technologies and cell therapies to treat solid tumors, focusing on protein design and T cell engineering to improve cancer treatment efficacy and safety.

BiotechDeep TechMedical DevicesSeattle, US

Marc Lajoie(Co-founder & Chief Executive Officer)inScott Boyken(Co-founder & Chief Technology Officer)inStanley Riddell(Co-Founder and Scientific Advisor)Aaron Foster(Executive Officer)inCharity Scripture(Executive Officer)inEric Soller(Executive Officer)in

Board seatJake Simson· per SEC Form D

Co-investorsArtis VenturesAbstract VenturesAtinum Investment Co. Ltd.Civilization Ventures Management, LlcModi VenturesPlayground Global+1 more

Stipple Biostipple.bioin𝕏Mar 2026 · $100M✓ verified

Stipple Bio develops targeted oncology therapies that act on tumor-specific cell surface epitopes to expand druggable targets and improve therapeutic index for cancer patients.

BiotechHealthtechCambridge, US

Aaron Ring(Co-founder)inAashish Manglik(Co-founder)inJeff Landau(Chief Executive Officer)inRoland Gendron(Chief Business Officer)inMichelle Zhang(Chief Scientific Officer)in

BoardVineeta Agarwala(Director)in

Board seatDerek DiRocco· per SEC Form D

Co-investorsAndreessen HorowitzMagnetic VenturesOMX VenturesAxial VCGV (Google Ventures)LoLa Capital Partners+1 more

Abcuroabcuro.comAug 2026✓ verified

Abcuro develops therapies that target highly cytotoxic T cells for autoimmune diseases, including its lead candidate ulviprubart for inclusion body myositis.

BiotechHealthtechNewton, US

Steven A. Greenberg(Chief Scientific Advisor & Co-Founder)Steven A. Greenberg, MD(Chief Scientific Advisor & Co-Founder)John Alexander Martin(Executive Officer, Director)Stefano Gulla(Executive Officer)Evan Thompson(Executive Officer)David de Graaf(Executive Officer, Director)

Co-investorsBain Capital Life SciencesNew Enterprise Associates (NEA)Samsara BioCapitalSanofi VenturesMass General Brigham VenturesREDMILE+8 more

Adcytherixadcytherix.comin✓ verified

Adcytherix is a clinical-stage biopharmaceutical company developing next-generation antibody-drug conjugates (ADCs) that use approved cancer drugs as payloads combined with optimized conjugation design to overcome resistance in precision oncology.

BiotechHealthtechMedical Devices

Jack Elands(Founder & CEO)inXavier Preville(Co-founder, VP & Head of Research & Preclinical Development)inJan H.M. Schellens(Chief Medical Officer)inThierry Menguy(VP & Head of CMC Operations)inJaime Arango(Chief Financial Officer)inPaul Jackson(Chief Operating Officer)in

Co-investorsaMoonBpifranceAndera PartnersAngelini VenturesKurma PartnersPontifax Venture Capital+1 more

Alchemab Therapeuticsalchemab.comin𝕏✓ verified

Alchemab operates a platform that identifies novel drug targets and therapeutics by analyzing patient antibody repertoires using deep B cell sequencing and computational analysis of samples from disease-resilient individuals.

AI & Machine LearningBiotechDeep TechHealthtech

Jane Osbourn(Chief Executive Officer)

Co-investorsSV Health InvestorsDCVC BioDementia Discovery FundLightstone VenturesOno Venture Investment, Inc.DCVC (Data Collective)

Alentisalentis.chin✓ verified

Alentis is a biotech company developing therapies for chronic liver disease, fibrosis, and cancer based on the molecular biology of liver disease.

AI & Machine LearningBiotechHealthtechMedical DevicesBasel, CH

Thomas Baumert(Founder)Mark Pruzanski(Chief Executive Officer)Luigi Manenti(Chief Medical Officer)Jon Freve(Chief Financial Officer)Bryan Yoon(General Counsel and Chief Administrative Officer)inAditya Venugopal(Chief Business Officer)in

Co-investorsAvego BioScience CapitalBioMedPartnersFrazier Life SciencesJeito CapitalLongitude CapitalNovo Holdings+5 more

Atavistik Bioatavistikbio.comin✓ verified

Atavistik Bio develops selective allosteric therapeutics using a proprietary discovery platform designed to identify functional pockets across multiple protein classes, with an internal focus on rare hematology.

BiotechHealthtechMedical Devices

Bryan E. Stuart(Chief Executive Officer)inMarion Dorsch(President and Chief Scientific Officer)in

Co-investorsLux CapitalThe Column GroupNextech Invest

Avalanche Energyavalanchefusion.comin𝕏Apr 2026 · $29M✓ verified

Avalanche Energy develops compact fusion technology to generate high-energy neutrons for materials testing, radioisotope production, and advanced nuclear battery systems serving defense, space, and commercial power applications.

Deep TechDefense TechEnergyRichland, US

Robin Langtry(Co-Founder, CEO)inBrian Riordan(Co-Founder, COO)in

Co-investorsCongruent VenturesFounders FundLowercarbon CapitalToyota VenturesAzolla VenturesJuniper+2 more

Biabia.appin𝕏Sep 2023✓ verified

Bia is a technology-driven electricity retailer in Colombia that lets businesses switch their energy provider and replace traditional meters with its proprietary BiaMonitor smart meter.

CleantechEnergyIoTBogota, CO

Sebastian Ruales(Founder)Guillermo Plaza Roche(Director)Leonardo Velazquez Florez(Director)Juan Sebastian Ruales Duque(Director)Jaime E. Zunzunegui(Director)

BoardNicolas Berman(Director)in

Co-investorsBBVA SPARKIDB LabKaszek VenturesMarathon VenturesNazcaNorte Ventures+2 more

Bright Peak Therapeuticsbrightpeaktx.comin✓ verified

Bright Peak Therapeutics is a biotechnology company developing multi-functional PD-1 inhibitors for cancer immunotherapy, based on its EDC protein-engineering platform.

BiotechHealthtechSan Diego, US

Vijaya Pattabiraman(Co-founder & Chief Technology Officer)inJeffrey Bode(Scientific Co-founder)inFredrik Wiklund(Chief Executive Officer)Christine Siu(Director)Michael Rosenzweig(Director)Bertolt Kreft(Executive Officer)

Co-investorsJohnson & Johnson Innovation – JJDCVersant VenturesVenrockFidelity InvestmentsInvusQatar Investment Authority

Capacity Biocapacitybio.cominDec 2022 · $35M✓ verified

Capacity Bio is a biotechnology company developing mitophagy modulators — small molecules, peptides, and nanoparticles that target mitochondrial biology to identify and clear dysfunctional mitochondria.

BiotechDeep TechLongevityPalo Alto, US

Amy Wang(PhD)Kenneth Horne(Executive Officer, Director)inDylan Morris(Director)Cristina Ghenoiu(Director)

BoardTaro Inaba(Director)in

Co-investorsRemiges Ventures, Inc.Insight PartnersAN Venture PartnersRDiscovery

Gracellbiogracellbio.comin✓ verified

Gracell Biotechnologies develops cell therapy manufacturing platforms and treatments, with a focus on CAR-T cell therapies for cancer and autoimmune diseases.

BiotechHealthtechMedical DevicesSuzhou, CN

William Wei Cao

Co-investorsLAVLilly Asia VenturesOrbiMedExome Asset ManagementJanus Henderson InvestorsPivotal Life Sciences+2 more

HYKU Bioscienceshykubiosciences.cominDec 2025✓ verified

Hyku Biosciences develops small molecule therapeutics with novel mechanisms of action designed to covalently bind non-cysteine amino acids and inactivate disease-driving proteins.

BiotechDeep TechMedical DevicesBurlington, US

KLEEM CHAUDHARY(Executive Officer, Director, Promoter)Ku-Lung (Ken) Hsu, PhD(Endowed Associate Professor of Chemistry)Kleem Chaudhary, PhD(President & CEO)

BoardJOHN GUSTOFSON(Director)LAURA BRASS(Director)inLAURA TADVALKAR(Director)

Co-investorsDroia VenturesEisai Innovation, Inc.Novartis Venture Fund

Indapta Therapeuticsindapta.comMay 2025✓ verified

Indapta Therapeutics develops an off-the-shelf, allogeneic FcRγ-deficient natural killer (g-NK) cell therapy derived from healthy donors to treat cancer and autoimmune diseases.

BiotechHealthtechHouston, US

Guy DiPierro(Chief Operating Officer & Co-Founder)inSungjin Kim(Scientific Founder)John Sunwoo(Scientific Founder)Mark W. Frohlich(Chief Executive Officer)Stefanie Mandl-Cashman(Acting Chief Scientific Officer)

BoardLori Hu(Director)

Co-investorsLeaps by BayerVertex Ventures HC

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106 more tracked companies

InozymeInterius BioIO BiotechIvantisJanuxJnana TherapeuticsJunoKalvistaKinnateKinnate BiopharmaKolomaLegend BioLenzLifeMineLumenaLyraMagenta MedicalMarianaMariana OncologyMBXMementoMerusMetagenomiMetseraMineralysMMI MicroModernaNapiGenNavaNavigator MedicinesNexCureNextopNiKang TherapeuticsNimbus TherapeuticsNivalisNorthLinks BioNucleixObsidian TherapeuticsOlemaOllinOptivoltOrchardPAhR TherapeuticsPandionPelotonPhathomPinnacle MedicinesPlantiblePluton BioPMV PharmaPoint BiopharmaPoplar TherapeuticsPrevailProfound BioProtagonistRa PharmaceuticalsRadenceReframe SystemsReframe SystemsRivus PharmaSatsumaSeagenSecretome TherapeuticsSerapha BioShockwaveSidera BioSierra OncologySilverback TherapeuticsSlate MedicinesSomatusSortera TechnologiesSparrow PharmaStar TherapeuticsStokeStylus MedicineSuperluminalSynapticureSynolo TherapeuticsSynthegoSynthekineSynthorxT-KnifeTaris BiomedicalTassoTenayaTerremotobioterrestrialThriveworksTopl (Now Plasma)Torl BioTrace NeuroscienceTriana BioTscanTScan TherapeuticsTypewriter TherapeuticsTyraVentusVentus TherapeuticsVerdiva BioVerve TherapeuticsViacyteVitriVaxVividionVoro MetalsWhiteSwellWindward Bio

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

Exits · 47

IPOs and acquisitions across the tracked portfolio

FreenomeNASDAQ: FRNMMineralys TherapeuticsNASDAQ: MLYSSpero TherapeuticsNASDAQ: SPROWave Life SciencesNASDAQ: WVEAclaris TherapeuticsNASDAQ: ACRSAdagio MedicalNASDAQ: ADGMAeglea BiotherapeuticsNASDAQ: SYREAgenusNASDAQ: AGENAktis OncologyNASDAQ: AKTSAN2 TherapeuticsNASDAQ: ANTXApogee TherapeuticsNASDAQ: APGEArcutis BiotherapeuticsNASDAQ: ARQTArvinas Holding Co. LLCNASDAQ: ARVNAtea PharmaceuticalsNASDAQ: AVIRBicara TherapeuticsNASDAQ: BCAXBioAge LabsNASDAQ: BIOABiohavenNYSE: BHVNBlack Diamond TherapeuticsNASDAQ: BDTXBolt BiotherapeuticsNASDAQ: BOLTBoundless BioNASDAQ: BOLDC4 TherapeuticsNASDAQ: CCCCCentury TherapeuticsNASDAQ: IPSCCeribellNASDAQ: CBLLCG OncologyNASDAQ: CGONClimbbioNASDAQ: CLYMConnect BiopharmaNASDAQ: CNTBDesign TherapeuticsNASDAQ: DSGNGH ResearchNASDAQ: GHRSImaraNASDAQ: ELVNNateraNASDAQ: NTRAnKartaNASDAQ: NKTXParabilis MedicinesNASDAQ: PBLSPepGenNASDAQ: PEPGPrecision BioSciencesNASDAQ: DTILPyxis OncologyNASDAQ: PYXSRani Therapeutics HoldingsNASDAQ: RANIRxsightNASDAQ: RXSTScribe TherapeuticsNASDAQ: SCTXSeres TherapeuticsNASDAQ: MCRBSionna TherapeuticsNASDAQ: SIONSolid BiosciencesNASDAQ: SLDBSpyglass PharmaNASDAQ: SGPVaxcyteNASDAQ: PCVXVor BiopharmaNASDAQ: VORXilio TherapeuticsNASDAQ: XLODTx Pharmaacq. by NovartisHilleVaxacq. by XOMA Royalty

Portfolio news

latest coverage across their companies

Public market activity · per SEC filings

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450 insider ownership filings (Forms 3/4/5)

at Septerna, Inc. (SEPN), Inhibikase Therapeutics, Inc. (IKT), Artiva Biotherapeutics, Inc. (ARTV), Freenome, Inc. (FRNM), Parabilis Medicines, Inc. (PBLS), Vor Biopharma Inc. (VOR), Climb Bio, Inc. (CLYM), ARS Pharmaceuticals, Inc. (SPRY)

From the firm's own SEC EDGAR filings — stakes and insider roles in public companies, typically portfolio companies after an IPO. Not a portfolio list published by the firm.

Frequently asked questions

How many investments has RA Capital made?
RA Capital has 265 tracked investments, 10 of which have exited via acquisition or IPO, including 22 dated in the last 24 months.
What stage does RA Capital invest at?
RA Capital invests at the Seed, Series A, Series B, Series C, Growth, Late Stage stages.
What sectors does RA Capital focus on?
RA Capital focuses on Biotech, Climate Tech, Digital Health, Healthtech, Medical Devices.
Where is RA Capital located?
RA Capital is headquartered in Boston, US.
Does RA Capital lead rounds?
RA Capital has led 6 of the 24 rounds where its role is on record.
Who does RA Capital co-invest with?
RA Capital most often shares deals with Foresite Capital, OrbiMed, Bain Capital Life Sciences, among 237 tracked co-investors.
What size deals does RA Capital back?
Across 13 deals with disclosed amounts, RA Capital has joined rounds of $20M – $318M (median $103M).

Media · Podcasts & interviews

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The Investor's Paradox with Peter Kolchinsky, RA Capital

Incubate Coalition · Peter Kolchinsky

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Co-investors · 71

Nextech Invest

Nextech Invest is a Zurich-based investment firm focused on emerging biotechnology companies, backing transformative cancer medicines and precision medicine advances worldwide.

$648K – $3.2M
Bain Capital Life Sciences

Bain Capital Life Sciences, founded in 2016, invests in biopharmaceutical, medical device, diagnostic, and life science tool companies globally, focusing on companies addressing unmet medical needs and driving medical innovation.

Andreessen Horowitz

Andreessen Horowitz (a16z) is a venture capital firm founded in 2009 by Marc Andreessen and Ben Horowitz, known for pioneering the platform model with a large team of operators supporting founders across stages.

$500K – $50M
Samsara BioCapital

Samsara BioCapital is an investment firm backing the development of transformative therapeutics for patients, bringing together scientists, physicians, drug developers, and business leaders to support next-generation therapeutic breakthroughs.

Sanofi Ventures

Sanofi Ventures is the corporate venture capital arm of Sanofi, investing in early-stage biotech and digital health companies focused on improving human health. It serves as Sanofi's entry point into the innovation ecosystem.

$5M
Vivo Capital

Vivo Capital is a global healthcare-focused investment firm operating a multi-strategy platform spanning venture capital, private equity, and public equity. It aims to expand healthcare access and drive innovation through its 'Ecosystem Strategy.'

$10M – $50M
GV (Google Ventures)

GV (Google Ventures) is a venture capital firm that has invested in artificial intelligence and machine learning since its early days, building a global portfolio of more than 100 AI companies across infrastructure, life sciences, and applications.

$250K – $50M
Canaan Partners

Canaan Partners is a venture capital firm with over 30 years of history, backing companies across technology and healthcare sectors through close, hands-on partnerships with founders.

$500K – $20M
Pfizer Venture Investments

Pfizer Venture Investments is a strategic venture fund that doesn't require product or technology rights as a condition of investing, giving founders independence while still aiming for future collaboration with Pfizer, and its team blends venture investing with business development and drug discovery expertise to back frontier scientific bets—such as neuroscience, in-vivo cell engineering, dark-genome target discovery, and the blockchain-based longevity accelerator VitaDAO—that many biotech investors avoid. The fund also runs an active China strategy through a locally based venture vehicle and direct investments like OTR Therapeutics, and it has become a channel for strategic deals, with portfolio companies acquired by AbbVie, Ipsen, and Gilead/Kite.

Both backed · 8
Bolt BiotherapeuticsArtios PharmaCapstan TherapeuticsMerusEnara BioJnana TherapeuticsNimbus Therapeuticsvisit www.trianabio.com
$5M – $20M
New Enterprise Associates (NEA)

New Enterprise Associates (NEA) is a venture capital firm that invests in and provides long-term support to founders building new companies.

$200K – $40M
59 more co-investors

F-Prime CapitalAtlas Venture5AM VenturesvenBio PartnersSV Health InvestorsVersant VenturesAndera PartnersMRL Ventures FundARCH Venture PartnersThird Rock VenturesAisling CapitalSR One Capital ManagementForbionPivotal Life SciencesNovartis Venture FundRTW Investments L.P.General CatalystInsight PartnersVenrockArtis VenturesMPM BioImpactThe Column GroupRed Tree VentureUS Venture PartnersEQT Life SciencesHatteras Venture PartnersNew Leaf Venture PartnersVertex Ventures HCHumboldtPolaris PartnersTwo Sigma VenturesPlayground GlobalJohnson & Johnson Innovation – JJDCYsios CapitalRoche Venture FundQiming Venture PartnersAnzu PartnersMedical Excellence CapitalHealthCapPsyMed VenturesOverwater Ventures LlcUnknown VenturesKleiner PerkinsCoatue ManagementAtomicoSignalFire23andMeXtripe AngelsBaruch Future VenturesMithril Capital ManagementXSeed CapitalAccess IndustriesOmega FundsTencent HoldingsCofounders CapitalAbbVieDe Novo VenturesQiming Venture Partners USANegev Capital

Firms observed investing alongside RA Capital, from public investor directories. Shared companies are the overlap with RA Capital's recorded portfolio.

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