Fundraising Fox
Sandbox Industries
Venture capitalChicago · Seed–Growth · 35 people tracked
Also known as 213 MANAGEMENT, LLC · SANDBOX HOLDINGS, LLC · SANDBOX INVESTMENT MANAGEMENT, LLC
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Investment thesis
Sandbox Industries invests in innovation aimed at transforming healthcare and insurance, industries it considers crucial to the future of human livelihood. It blends traditional venture investing with corporate strategic investing by bringing industry leaders in as strategic limited partners, creating ecosystems that connect strategic investors, financial investors, and portfolio companies. Through vehicles such as the Blue Venture Funds—a collaboration with Blue Cross Blue Shield companies and the BCBS Association—it backs venture and growth opportunities in healthcare technology, healthcare services, and clinical sciences. In insurance, it invests in technology transforming insurance and financial services, leveraging relationships with leading insurers.
Source: firm website, verified Sep 29, 2026.
Team · 35 people
from the firm's website & curated & public directories
Founder mafia
5 people who came through Sandbox Industries went on to found or lead other companies.
What they invest in
from 34 of 51 portfolio companiesHealthtech ×16Digital Health ×15AI & Machine Learning ×13Biotech ×8Enterprise Software ×8SaaS ×8Fintech ×6InsurTech ×5
HQs:United States×26United Kingdom×2Ireland×1Mexico×1
Investments · 51 tracked
founders shown can be your intro pathBy year:2026 · 12025 · 62024 · 12022 · 12021 · 12020 · 42019 · 22018 · 22017 · 22016 · 22014 · 32011 · 126 dated
Debut applies AI and biotechnology to discover and formulate cosmetic ingredients and beauty products, decoding skin and hair at the genomic level to create novel actives.
Advanced ManufacturingAI & Machine LearningBiotechConsumerSan Diego, US
Joshua Britton(Founder)in
BoardCain A. McClary(Director)in
Co-investorsGS FuturesMaterial ImpactBreakout VenturesKdT VenturesACVC PartnersBetter Ventures Central Llc+11 more
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Nest Health provides convenient, in-home and virtual healthcare for families, aiming to serve patients regardless of location or insurance status.
Digital HealthFemTechHealthtechImpact & Social GoodNew Orleans, US
Rebekah E. Gee MD MPH(Founder)inRebecca Kavoussi(Co-founder)inRebekah Gee(Chief Executive Officer & Founder)inMichael Meador(Executive Officer)inJanell Wilson(Executive Officer)inKelsie Brandt(Chief Operating Officer)in
Co-investorsAlumni Ventures8VCAmboy Street VenturesGaingelsHopelabImpact America Fund+9 more
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Octave develops blood-based biomarker tests for neurodegenerative diseases including multiple sclerosis, Parkinson's disease, and Alzheimer's disease.
AI & Machine LearningBiotechDigital HealthMedical DevicesMenlo Park, US
William Hagstrom(Founder and Chairman)inDoug Biehn(President and CEO)in
Co-investorsNorthpond VenturesSection 32Blue Venture FundsEcho Health VenturesHikma VenturesMerck Global Health Innovation Fund+3 more
AbleTo provides in-person and virtual mental health care, including therapy, psychiatry, and medication management for adults, children, and teens dealing with concerns such as anxiety, depression, ADHD, and substance use.
Digital HealthHealthtechMental HealthNew York, US
Michael Laskoff(Executive Officer, Director)Trip HoferinPaul Pieper(Executive Officer)Tom Brennan(Executive Officer)Frank Hunt(Executive Officer)Robert Rebak(Executive Officer, Director)
Co-investors.406 VenturesBain Capital VenturesBlue Venture FundsHLM Investment PartnersOptum VenturesValspring Capital+1 more
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Anzen develops thermoelectric heating, cooling, and ventilation technology for residential buildings to reduce carbon emissions cost-effectively.
CleantechClimate TechEnergyHardware
Michael Reid(CTO)
BoardSaffa Riffat(President of World Society of Sustainable Energy)
Co-investorsGreen Angel VenturesOne Planet CapitalSustainable VenturesAndreessen HorowitzCreator FundLocalGlobe
Anzen operates USDz, an on-chain stablecoin backed by a diversified portfolio of overcollateralized real-world assets, primarily asset-backed private credit securities.
Crypto & Web3Fintech
Co-investorsArca FundsCircle VenturesKraynos CapitalAndreessen HorowitzBlocktower CapitalCreator Fund+1 more
Nashville-based provider of home and outpatient community-based palliative care for seriously ill patients, acquired by Anthem in 2018.
Digital HealthHealthtechNashville, US
Brad Smith(Executive Officer, Director)Andrew Lasher(Executive Officer)Diane Seloff(Executive Officer)William Anderson(Executive Officer)inWilliam Frist(Director)in
BoardAnn Lamont(Director)in
Co-investorsBlue Venture FundsFrist Cressey VenturesGV (Google Ventures)Lifeforce CapitalMountain Group CapitalOak HC/FT
Big Health develops digital treatments and care programs for mental health conditions, including cognitive behavioral therapy-based solutions for insomnia and other mental health issues.
Digital HealthHealthtechMental Health
Peter Hames(Co-founder)inColin Espie(Co-founder)
Co-investors.406 VenturesAlleyCorpBlue Venture FundsIndex VenturesInnovation Global CapitalKaiser Permanente Ventures+8 more
Minneapolis, US
Patrick Christie(Executive Officer, Director)
BoardRobert Shapiro(Director)inRichard Pavelski(Director)
Co-investorsAliment CapitalCultivian Sandbox VenturesPontifax AgTechMiddleland CapitalPontifax Global Food Agriculture Technology
Co-investorsCultivian Sandbox Ventures
Daymark provides 24/7 in-home and virtual cancer care, offering patients an oncology-specialized team available by phone, text, video, or home visits to coordinate testing, manage symptoms and medications, and handle care logistics.
Digital HealthHealthtechMental HealthPhiladelphia, US
Justin Bekelman(Executive Officer, Director)inJonathan Rhodes(Founder)inPaul Dufault(Executive Officer)Roy Beveridge(Director)
BoardKelsey Maguire(Director)Ambar Bhattacharyya(Director)
Co-investorsBlue Venture FundsHealthier CapitalMaverick VenturesOncology VenturesAlpha PartnersYosemite
Descartes Labs was a Los Alamos-spinoff geospatial analytics company that used AI to process satellite imagery for agriculture, mining, insurance, and government clients.
Santa Fe, US
Mark Johnson(Executive Officer, Director, Promoter)Steven Brumby(Director)Mike Warren(Founder)inSuzanne McBride(Director)Andrew Ziolkowski(Director)James Montgomery(Director)
Co-investorsCorrelation VenturesCrosslink CapitalCultivian Sandbox VenturesDCVC (Data Collective)Hemisphere Ventures LLCIndustrious Ventures+5 more
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Geltor uses a proprietary biodesign and precision fermentation platform to create and commercially produce novel protein ingredients, including collagens, for beauty and personal care formulators.
BiotechFoodTechNew MaterialsWellness & Fitness
Alexander Lorestani(Founder)inNick Ouzounov(Co-founder)in
Co-investorsAgronomicsAlwyn CapitalArgonautic VenturesBaruch Future VenturesBlue Horizon CorporationBoxGroup+16 more
Gradient AI develops underwriting and claims management software for group health, property & casualty, and workers' compensation insurance.
AI & Machine LearningData & InfrastructureDigital HealthEnterprise SoftwareHealthtechInsurTechDurham, US
Stan Smith(Founder & CEO)inOuwen Huang(Executive Officer, Director)inJoshua Miller(Executive Officer, Director)in
BoardShana Barghouti(Director)Satish Tadikonda(Director)inMatt Bailey(Director)
Co-investorsAmerican Family VenturesBoro CapitalMassMutual VenturesMedMountain VenturesSilicon ValleySupernode Ventures+4 more
WellSky operates a network connecting post-acute and social care providers with health plans and government organizations to enable coordinated care management programs.
Digital HealthEnterprise SoftwareHealthtechSaaS
Co-investorsBlue Venture FundsKapor CapitalActivate Venture PartnersPrimary Venture Partners
Indico provides an intake and orchestration platform for insurance carriers that processes unstructured data such as claims, submissions, and reports to modernize how work enters and moves through insurance operations.
AI & Machine LearningEnterprise SoftwareInsurTechSaaSBoston, US
Madison May(Founder & CTO)inDiana Yuan(Co-founder, SVP People & Operations)inAlec Radford(Co-founder and Advisor)inSlater Victoroff(Executive Officer, Director)in
Co-investors.406 VenturesBoston Seed CapitalHyperplane Venture CapitalOsage Venture PartnersTechstarsAviva Ventures
IngredientWerks is a molecular farming company that engineers plants to produce plant-based proteins and ingredients for the alternative protein market.
AgTechBiotechFoodTechWoburn, US
Matt Plavan(Chief Executive Officer)inMichael Raab(R&D Lead)Jeremy Schley-Johnson(Vice President)inSteve Snyder(Director)James Schultz(Director)
BoardClinton Bybee(Director)in
Co-investorsARCH Venture PartnersOpen PrairieCultivian Sandbox Ventures
Intellivo provides health plan subrogation services for employers and health plans, helping recover costs and protect plans while maintaining member experience.
AI & Machine LearningEnterprise SoftwareFintechHealthtechInsurTechSaaS
Co-investorsThompson Street Capital Partners
Lumeris uses AI combined with human-centered design to address the U.S. primary care shortage, co-creating an AI tool called Tom with physicians and patients to deliver Primary Care as a Service.
AI & Machine LearningDigital HealthHealthtechSt. Louis, US
W. Michael Long(Chairman & Chief Executive Officer, Lumeris Group Holdings Corporation)
Co-investorsBlue Venture FundsHavencrest Capital ManagementKleiner PerkinsBlueCross BlueShield Venture PartnersDeerfield Management Company
San Mateo, US
Aditya Damle(Executive Officer, Director)David Kim(Executive Officer, Director)in
BoardLarry Leisure(Director)Matt Downs(Director)Euan Thomson(Director)
Co-investorsAlumni VenturesALLEGISNL CAPITALBlueCross BlueShield Venture PartnersKhosla Ventures
Nuritas uses a proprietary AI platform, the Nuritas Magnifier, to discover and clinically validate bioactive peptide ingredients derived from natural sources.
AI & Machine LearningBiotechFoodTechDublin, IE
Dr. Nora Khaldi(Founder & CEO)inJohn Casey(Chief Manufacturing & Supply Chain Officer)inConor Walshe(Chief Financial Officer)inAlison Anderson(Chief People Officer)in
Co-investorsCleveland AvenueMcWin Capital PartnersMarc BenioffEuropean Circular Bioeconomy FundKeiretsu ForumCultivian Sandbox Ventures
Perspectum develops digital medical technology and diagnostics using multiparametric MRI to assess and diagnose chronic systemic diseases including liver disease, long COVID, diabetes, and cancer for clinicians and patients.
AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesOxford, GB
Rajarshi Banerjee(CEO)in
Co-investorsBlue Venture FundsOxford Science EnterprisesBritish Patient CapitalHealthQuest Capital
Technology identifying supply chain sources using the environmental microbiome.
Co-investorsDolby Family VenturesGolden SeedsJ-VenturesWorking Capital FundAgFunderBlackhorn Ventures+4 more
PinkDx is a diagnostics company developing tests, led by a leadership team spanning scientific, medical, and business functions.
BiotechDigital HealthFemTechIndianapolis, US
Richard T. Kloos(Chief Medical Officer)inTimothy McMeekan(Co-Founder, Chief Financial Officer, and Chief Business Officer)Giulia Kennedy(Co-Founder and Chief Scientific Officer)Isaac Ro(Director)inRisa Stack(Director)inEric Wang(Executive Officer)
Co-investorsBEVCBlue Venture FundsCatalio Capital Management, LPMountain Group Capital
Prove offers a business onboarding and verification solution that reduces manual input by validating business entities, EIN/TIN, and documents while connecting an individual applicant to a business through mobile device and phone number authentication.
CybersecurityFintechSaaS
Co-investorsMassMutual VenturesOak HC/FTRealization Capital PartnersRelay VenturesRRE VenturesStack Capital
Solera operates a digital health delivery network and matching platform that guides health plan members and employees to virtual condition-management programs from over 30 digital providers.
AI & Machine LearningB2B MarketplacesDigital HealthHealthtechSaaSPhoenix, US
Brenda Schmidt(Executive Officer, Director)in
Co-investorsBlue Venture FundsCobalt VenturesSJF VenturesAdams Street PartnersAlliance Healthcare FoundationHorizon Blue Cross Blue Shield of New Jersey
AgTechEmeryville, US
Eric Davidson(Director)inTravis Bayer(Director)inPaul Beck(Executive Officer)inDave Vosburg(Executive Officer)Adam Litle(Executive Officer, Director)inDerek Norman(Director)in
Co-investorsCavallo VenturesCultivian Sandbox VenturesFall Line CapitalS2G InvestmentsFootPrint CoalitionLeaps by Bayer+2 more
Supergut makes fiber-based food and supplement products aimed at supporting gut microbiome health for consumers.
Direct to ConsumerFoodTechWellness & Fitness
Marc Washington(Founder)in
Co-investorsAcre Venture PartnersAlpha EdisonAOKI LABSAssembled BrandsGreat Circle VenturesThe Family Fund+3 more
SwipeSense is a healthcare technology company that provides a hospital safety platform with applications for electronic hand hygiene monitoring, real-time asset tracking, automated contact tracing, and nursing insights.
AI & Machine LearningDigital HealthEnterprise SoftwareHealthtechIoTChicago, US
Mert Iseri(Executive Officer, Director)inYuri Malina(Executive Officer, Director)inAndrew Berthusen(Chief Executive Officer)
BoardLior Susan(Director)inRandall Crowder(Director)inDaniel Phillips(Director)
Co-investorsBlue Venture FundsNat TurnerNew Ground VenturesTEXO VenturesEclipse Ventures
Swoop provides a privacy-safe, AI-driven commercial intelligence and marketing platform that uses de-identified real-world patient and HCP data to coordinate targeted engagement across channels like display, connected TV, social, and point-of-care.
AdTechAI & Machine LearningDigital HealthHealthtech
Co-investorsArcher Capital GroupUS Venture Partners
FeeFighters is a fee-reduction service for small and medium businesses that audits and negotiates credit card processing fees to lower merchant costs, without requiring companies to switch processors.
FintechMountainside, US
Joshua KrallSteve HarperSean Harper(Founder)in
Co-investors500 GlobalHyde Park AngelsOCA Ventures
Verituity provides a payouts platform that delivers verified, on-time payments with payment choice for businesses and their payees, aiming to reduce payout complexity, risk, and cost.
Enterprise SoftwareFintechSaaSMclean, US
Ben Turner(Chief Executive Officer & President)inChris Smith(Chief Operating Officer)inAnthony Renzette(Chief Product Officer)inAndy Brooks(Chief Financial Officer)in
BoardDonald Dixon(Director)inPhilip Bronner(Director)in
Co-investorsArdent VentureForgePoint CapitalMTECH CAPITAL
Vestaron develops peptide-based insecticides derived from naturally-occurring peptides such as those found in spider venom, produced through fermentation, offering new modes of action for crop protection.
AgTechBiotechCleantechClimate TechNew MaterialsKalamazoo, US
Glenn King(Founder)inJuan Estupinan(Executive Officer, Director)inDawn de los Santos(Executive Officer)inRobert Kennedy(Executive Officer)Nancy Newman(Executive Officer)inJohn C. Sorenson(Executive Officer, Director)
Co-investorsArgonautic VenturesCavallo VenturesCultivian Sandbox VenturesEndeavor8iSelect FundMichigan Capital Network+4 more
ZeOmega provides healthcare enterprise management software for health plans and other risk-bearing organizations, offering integrated care management, prior authorization, and workflow solutions.
AI & Machine LearningCloud ComputingDigital HealthEnterprise SoftwareHealthtechSaaSPlano, US
Co-investorsBlue Venture FundsBlueCross BlueShield Venture PartnersBregal Sagemount
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Advanced Animal DiagnosticsAxial HealthcareCopper Cow CoffeeCulture BiosciencesData WorldLeafNovihumPayfoneReinRollickVerata Health (Now Part of Olive)Yard Stick
Exits · 4
4 acquisitions · showing 2Aspire Healthacq. by CareMore Health (Anthem)Healthifyacq. by WellSky
Portfolio news
latest coverage across their companiesNest Health · finsmes.com · Nov 24, 2025
SwipeSense · swipesense.com · Oct 30, 2025
Indico Data · finsmes.com · Oct 28, 2025
Geltor · geltor.com · Oct 13, 2025
Octave · finsmes.com · Sep 5, 2025
Daymark Health · prnewswire.com · Apr 3, 2025
Frequently asked questions
- How many investments has Sandbox Industries made?
- Sandbox Industries has 51 tracked investments, 4 of which have exited, including 7 dated in the last 24 months.
- What stage does Sandbox Industries invest at?
- Sandbox Industries invests at the Seed, Series A, Series B, Series C, Growth stages.
- What sectors does Sandbox Industries focus on?
- Sandbox Industries focuses on Biotech, Digital Health, Fintech, Healthtech, InsurTech, Medical Devices.
- Where is Sandbox Industries located?
- Sandbox Industries is headquartered in Chicago, US.
- Does Sandbox Industries lead rounds?
- Sandbox Industries typically participates in rounds rather than leading them.
Media · Podcasts & interviews
featuring the teamSandbox Industries' Nick Rosa: On Entrepreneurship
ExcelerateLabs · Nick Rosa
Images
Co-investors · 32
.406 Ventures is an early-stage venture capital firm that partners with founders building companies in healthcare, data and AI, and cybersecurity.
Oak HC/FT is a growth equity firm that partners with founders building companies in healthcare and financial services, leveraging sector expertise and networks.
Northpond Ventures is a venture capital firm based in Bethesda, Maryland that invests in life sciences, technology, and related sectors.
RRE Ventures is a boutique early-stage venture capital firm that backs founders across sectors, combining decades of experience with AI-driven analysis throughout the investment lifecycle.
GV (Google Ventures) is a venture capital firm that has invested in AI and machine learning since its early days, backing more than 100 AI companies across infrastructure, life sciences, and applications.
Khosla Ventures is a venture capital firm that backs bold, early-stage, technology-driven companies across deep tech and other sectors, providing hands-on 'venture assistance' to help founders build category-defining businesses.
Mayfield is a venture capital firm that invests in early-stage consumer and marketplace companies, backing founders from inception through IPO.
NextGen Venture Partners (NGVP) is an early-stage venture firm that leads seed investments in B2B startups, backing companies from seed to scale.
Relay Ventures is an early-stage venture capital firm that backs founders from pre-seed and seed through later financing stages, focusing on companies solving major pain points in large, high-growth markets.
ForgePoint Capital is a thesis-driven venture firm investing in early-stage companies in cybersecurity, AI, and infrastructure software.
HealthQuest Capital is a healthcare-focused investment firm that backs transformative healthcare companies, primarily at the commercial stage, through Growth Equity and Tactical Opportunities strategies.
▶20 more co-investors
Craft VenturesBessemer Venture PartnersSOSVAccompliceInitialized CapitalCoinbase VenturesSilverton PartnersNext Coast VenturesAZ-VCAsset Management VenturesSV Health InvestorsMeridian Street CapitalTencent HoldingsRpm Ventures Iii Management, L.L.C.CVS Health VenturesFlyover CapitalAction Potential Venture Capital Ltd.Saltagen Venturesmark vcGermin8 Ventures
Firms observed investing alongside Sandbox Industries, from public investor directories. Shared companies are the overlap with Sandbox Industries's recorded portfolio.
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