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Axial VC

Venture capital

San Francisco · Pre-Seed–Series A · 2 people tracked

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Investment thesis

Invests in early-stage life sciences companies, often backing founders when they are no more than an idea.

Stage
Pre-Seed–Series A
Check
$100K – $5M
HQ
San Francisco, California, US
Leads rounds
Follows
Founded
2019
Tracked investments
53

Team · 2 people

from public directories

What they invest in

from 44 of 53 portfolio companies

Biotech ×35AI & Machine Learning ×19Healthtech ×19Deep Tech ×14Medical Devices ×10Digital Health ×7Wellness & Fitness ×5Consumer ×4

HQs:United States×25Australia×1Switzerland×1

Investments · 53 tracked

founders shown can be your intro path

By year:2025 · 12024 · 22020 · 12019 · 15 dated

Adaptyvadaptyvbio.comin𝕏

Adaptyv Bio develops technologies for protein engineering that enable the design and testing of new proteins for applications in medicine, industrial enzymes, and functional materials.

AI & Machine LearningBiotechDeep TechHealthtechLausanne, CH

Julian Englert(Founder)inDaniel Nakhaee-Zadeh Gutierrez(Founder)inRobert KapturGerard AntounSam Burns

Co-investorsHAWKTAILNeer Venture PartnersRheingau FoundersUnruly CapitalY CombinatorACE & Company+2 more

Aperiam Bioaperiambio.comin

Aperiam Bio develops protein engineering services, using algorithms to design and optimize hyper-folding protein variants through mutagenesis, testing, and validation.

AI & Machine LearningBiotechDeep TechAustin, US

Austin Cole(CEO & Founder)Guillaume Cottarel(Head of Program)Russell Durrett(Chief Business Officer)

Co-investorsCivilization Ventures Management, LlcOMX VenturesKdT Ventures

Appiabioappiabio.com

Co-investors8VC

Arda Therapeuticsardatherapeutics.comin𝕏

Arda Therapeutics is a drug development company that uses single-cell computational biology to identify and eliminate pathogenic cells as a way to treat chronic diseases.

AI & Machine LearningBiotechDigital HealthLongevityMedical Devices

Adam Freund(Founder & Chief Executive Officer)Remi-Martin Laberge(Founder & Chief Technology Officer)

Co-investorsGV (Google Ventures)

attivareattivaretx.com

Attivare develops AI-powered personalized immunotherapy treatments using a proprietary biomaterial scaffold (ATTImmune) that delivers immune agonists directly to tumor microenvironments, aiming to reduce systemic toxicity in cancer and infectious disease treatment.

AI & Machine LearningBiotechMedical DevicesNatick, US

Edward Doherty(Executive Officer)Jessica McDonough(Director)Joaquim Trias(Executive Officer, Director)

BoardZeshan Muhammedi(Director)

Co-investorsMBX CapitalUlu VenturesEmbark Ventures

BigHat Biosciencesbighatbio.comin𝕏

Big Hat Bio develops therapeutics under development across multiple programs.

AI & Machine LearningBiotechDeep TechSan Francisco, US

Peyton Greenside(Executive Officer, Director)Mark DePristo(Executive Officer, Director)

BoardFrancisco Gimenez(Director)inSteve Kafka(Director)Vineeta Agarwala(Director)inRobert Chess(Director)

Co-investors8VCAndreessen HorowitzBOLD LongevityFlucas VenturesAME Cloud VenturesSection 32

BLUUMBIObluumbio.comin𝕏

BluumBio identifies and deploys naturally occurring enzymes from fungi, trees, and bacteria to remove industrial pollutants from soil, air, and water.

BiotechCleantechHealthtechImpact & Social GoodSan Francisco, US

Katherine French(Founder)in

Co-investorsOlive Tree CapitalOxonian VenturesY Combinator

Bristlebristlehealth.comin𝕏

Bristle provides digital tools and insights to help people assess and improve their oral health, positioning dental care as a preventive step toward overall wellness.

Digital HealthHealthtechWellness & FitnessSan Francisco, US

David Lin(Founder)inBrian Maurer(Founder)inShivam Patel(Founder)in

Co-investorsR/GA VenturesY CombinatorInitialized Capital

Catena Biosciencescatenabiosciences.comin𝕏

Catena develops a conjugation platform for antibody-drug conjugates (ADCs) and multi-payload conjugates used in oncology for solid tumors.

BiotechDeep TechHealthtechMedical DevicesSan Francisco, US

Marco Lobba(Founder)inMatthew Francis(Founder)in

Co-investorsCivilization Ventures Management, LlcIaso VenturesY CombinatorLongeVCMBX CapitalSocial Impact Capital

Cellafarmscellafarms.com

Cella Farms develops food products focused on complete protein, reduced sugar, and balanced nutrition.

ConsumerFoodTechWellness & Fitness

Charmtxcharmtx.com

CHARM is a biotech company developing a next-generation menin inhibitor for acute myeloid leukemia (AML), designed to address resistance seen with first-generation approaches.

AI & Machine LearningBiotechHealthtech

Co-investorsF-Prime Capital PartnersOrbiMedNVentures

Colorado Biofactorycoloradobiofactory.comin𝕏Nov 2024

Colorado Springs, US

Thaddaus Huber(Executive Officer, Director)

BoardRik Wehbring(Director)Michael Cantrell(Director)

Concertobioconcertobio.comin𝕏

Concerto develops microbial technologies inspired by microbial ecology, aiming to create products that protect human health, food, and the environment.

AgTechAI & Machine LearningBiotechDeep TechCambridge, US

Jared Kehe(Executive Officer, Director)Cheri Ackerman(Executive Officer, Director)Bernardo Cervantes(Executive Officer, Director)Vera Schroeder(Director)

BoardSarah Luppino(Director)in

Co-investorsExcelestar VenturesGolden SeedsHorizons VenturesISVMassVenturesM Ventures

Deciduous Therapeuticsdeciduoustx.comJun 2019

Deciduous Therapeutics develops small molecule and immunomodulatory therapies targeting senescent cells to treat age-related diseases including Type 1 diabetes, autoimmunity, and metabolic disorders.

BiotechDigital HealthLongevitySan Francisco, US

Robin Mansukhani(CEO and Co-Founder)inAnil Bhushan(Scientific Founder)in

BoardDylan Morris(Director)in

Co-investorsage1Bold Capital PartnersCornucopian Capital ManagementCRV (Charles River Ventures)Owl CapitalquadraScope Venture Fund

Delixdelixtherapeutics.comin

Delix Therapeutics develops third-generation, non-hallucinogenic neuroplastogens for people with neurological conditions, using a discovery platform to identify novel compounds.

BiotechDigital HealthMedical Devices

Co-investorsArtis VenturesCasa Verde CapitalNoeticOMX VenturesPsyMed VenturesRA Capital+3 more

Enable Medicineenablemedicine.comAug 2020

Enable Medicine builds an integrated biological data platform that organizes and links clinical, spatial, cellular, and molecular data from patients and studies into a unified index to accelerate therapeutic discovery and diagnostics for researchers.

AI & Machine LearningBiotechData & InfrastructureMenlo Park, US

Sunil Bodapati(Executive Officer, Director)Aaron Mayer(Director)in

Co-investorsBreyer CapitalInertia Ventures

Eulereuler.bio

Euler Biologics develops antibody-based therapies aimed at preserving and enhancing physical function in older adults to support healthy aging and functional independence.

BiotechHealthtechLongevity

Getrevelagetrevela.com

The site presents Thai-language promotional content for online slot ("สล็อตเว็บตรง") gambling, listing direct-web slot sites with automatic wallet deposits/withdrawals and hundreds of games.

Co-investorsBantam GroupHyphen Capital

Glyphic Biotechnologiesglyphic.bioin𝕏Feb 2024

Glyphic Biotechnologies develops ProSE™, a high-throughput de novo protein sequencing technology for analyzing proteomes with single-molecule sensitivity.

BiotechDeep TechBerkeley, US

Joshua Yang(Founder & CEO)Daniel Estandian(Founder)Ed Boyden(Founder)

BoardCraig Asher(Director)inJimmy Yun(Director)

Co-investorsArtis VenturesBlack FlagCivilization Ventures Management, LlcFoundersX VenturesLongeVCModi Ventures+3 more

Immulusimmulus.com

Co-investorsBlue Bear Ventures

Inductive Bioinductive.bioin𝕏Mar 2025

Inductive Bio builds AI and machine learning software to accelerate drug discovery for pharmaceutical and biotech researchers, combining computational chemistry with expertise in translating complex drug programs from preclinical to clinical stages.

AI & Machine LearningBiotechDeep TechBrooklyn, US

Josh Haimson(Executive Officer, Director)inBen Birnbaum(Ph.D.)inAlexander Taylor(Ph.D.)in

BoardRohan Ganesh(Director)in

Co-investorsAlleyCorpAndreessen HorowitzCoalition OperatorsLux CapitalObvious VenturesAlley Robotics Ventures+3 more

Infinimmuneinfinimmune.comin

Infinimmune discovers and develops antibody therapeutics using proprietary sequencing technology and AI-powered optimization.

AI & Machine LearningBiotechMedical Devices

Lance Hepler(Founder)in

Co-investorsCivilization Ventures Management, LlcPlayground Global

Insamoinsamo.com

Insamo develops an automated platform for drug discovery that designs, synthesizes, and tests cyclic peptides at scale using machine learning and proprietary experimental data.

AI & Machine LearningBiotechDeep TechChippendale, AU

TIMOTHY CRAVEN(Executive Officer, Director)TOBY PASSIOURA(Executive Officer, Director)Tim Craven(CEO)Toby Passioura(CSO)Glen McIntyre(COO)GLEN MCINTYRE(Executive Officer, Director)

Co-investorsCivilization Ventures Management, LlcMRL Ventures FundPlayground GlobalvenBio PartnersvenBio Global Strategic

Kiwi Biosciencesfodzyme.comin𝕏

FODZYME develops an enzyme powder supplement that breaks down FODMAPs in food, particularly fructans found in garlic, onions, and wheat, for people with digestive sensitivities.

BiotechConsumerFoodTechHealthtechWellness & FitnessBoston, US

Anjie Liu(Founder)inDavid Hachuel Gurska(Founder)in

Co-investorsY Combinator

Laddertxladdertx.com
Latchbiolatchbio.comin𝕏

Latch builds verifiable benchmarks and deploys AI agents for analyzing real-world biological data across areas such as spatial, single-cell, epigenomics, preclinical pharmacology, and biosecurity.

AI & Machine LearningBiotechDeep Tech

Lyelllyell.com

Lyell is a clinical-stage biotech developing next-generation CAR T-cell product candidates intended as one-time treatments for patients with cancer, targeting both hematologic malignancies and solid tumors.

BiotechHealthtech

Co-investorsvenBio Partners8VC

Meliora Therapeuticsmelioratherapeutics.com

Machine learning and data platform for understanding how diseases fight back and resist therapies

Co-investorsHAWKTAILValkyrie

Nexiliconexilico.com

Nexilico is a biotech company that uses an AI-driven discovery platform and proprietary microbiome digital twin technology to engineer the microbiome for precision medicine.

AI & Machine LearningBiotechDigital Health

Nuancedhealthnuancedhealth.comin

Nuanced Health operates a preclinical drug discovery and development platform that humanizes the mouse microbiome to recreate the biological heterogeneity of human populations.

AI & Machine LearningBiotechDeep Tech

Co-investorsFREEFLOWOpen Field Capital

Omicaomica.bio
Options MDoptionsmd.comin

Wellness & FitnessLos Angeles, US

Kyle Pierce(Executive Officer, Director)inMorgan Hewett(Executive Officer, Director)

Co-investorsBread And Butter Ventures, LlcTechstarsBread Butter VenturesBright VenturesCollab CapitalM13+1 more

Papapapa.comin𝕏

Papa is a platform that connects older adults and families with trained companion caregivers for in-home companionship and support services.

ConsumerDigital HealthHealthtechSocialWellness & FitnessMiami, US

Andrew Parker(Founder/CEO)inAlfredo Vaamonde(Co-Founder)inAndrew(CEO)in

Co-investorsComcast VenturesIntegra GroupeMagnify VenturesSoftBank Vision FundThe Chernin Group (TCG Crypto)Y Combinator+2 more

Parallel Bioparallel.bioin𝕏

Parallel Bio develops human immune organoids and computational tools to predict drug efficacy across diverse patient populations, replacing animal testing in drug discovery.

AI & Machine LearningBiotechDeep TechHealthtechSan Francisco, US

Robert DiFazio(Founder)inJuliana Hilliard(Founder)in

Co-investorsAIX VenturesBreakout VenturesHumba VenturesImmeasurableJulian CapitalMetaplanet+5 more

Parallelhealthparallelhealth.io

Parallel Health is a licensed teledermatology practice offering the MD-03 Protocol, a three-step system combining whole genome microbiome sequencing, 1:1 clinical consultations, and custom phage-based serums.

BiotechDigital HealthDirect to Consumer

Co-investorsFirst In VenturesHyphen Capital

Potionpotion.aiin𝕏

Potion creates automation and workflow solutions for beauty and personal care companies to reduce time spent on repetitive tasks.

AI & Machine LearningConsumerEnterprise SoftwareMarketing TechSaaSSan Francisco, US

Yahya Syed(Founder)inHejab Malik(Founder)inAlex Stec(Founder)in

Co-investorsHAWKTAILY Combinator

Reference Medicinereferencemedicine.comin𝕏

Reference Medicine supplies quality-controlled human oncology specimens to research teams, sourcing samples across cancer indications from IRB/EC-accredited institutions worldwide.

B2B MarketplacesBiotechHealthtech

Co-investorsMetaplanet

Replay Therapeuticsreplay.bio

Replay develops gene therapies for patients with rare genetic diseases.

BiotechHealthtechLongevity

Lachlan MacKinnon(CEO and Founder)Adrian Woolfson(Founder)Robert Coffin(Executive Chairman)Maria Castner-Miller(General Counsel)Renata Martin(VP & Head of Gene Therapy)Saurabh Sharma(VP & Head of CMC)

Co-investorsArtis VenturesOMX VenturesSolari Capital

Rubi Laboratoriesrubilaboratories.comin𝕏

Advanced ManufacturingAlameda, US

Neeka Mashouf(Executive Officer, Director)Leila Mashouf(Executive Officer, Director)

BoardDaria Hosseinyoun(Director)Rohini Finch(Director)

Saniarxsaniarx.comin𝕏

Sania Rx develops precision therapies that target the nervous system to treat prevalent and underserved disorders.

BiotechMedical Devices

Seranova Bioseranovabio.comin

BiotechNew Haven, US

Aaron Ring(Manager)Beatrice McQueen(Executive Officer)

BoardJim Tananbaum(Manager)

Co-investorsARCH Venture Partners

Simcha Therapeuticssimchatx.comin

Simcha Therapeutics is a clinical-stage biotech company developing protein therapeutics, with pipeline programs focused on cytokines and immunotherapies for oncology.

BiotechHealthtechNew Haven, US

Aaron Ring(Executive Officer, Director)Beatrice McQueen(Chief Operating Officer)Sanuj Ravindran(Chief Executive Officer)Jeremy Barton(Chief Medical Director)Hirdesh Uppal(Senior Vice President Translational Research and Development Sciences)Joseph Catino(Executive Officer)

Co-investorsConnecticut InnovationsPfizer Venture InvestmentsSR One Capital Management

Stately Biostatelybio.com

Stately Bio develops stem cell-derived regenerative and cell therapies using a machine learning platform that measures cell identity, behavior, and maturation directly from live-cell, label-free imaging.

AI & Machine LearningBiotechMedical Devices

Co-investorsAIX VenturesFoothill VenturesMitsui Global InvestmentBoxOne VenturesDimension Capital

Stipple Biostipple.bioin𝕏

Stipple Bio develops targeted oncology therapies that act on tumor-specific cell surface epitopes to expand druggable targets and improve therapeutic index for cancer patients.

BiotechHealthtechCambridge, US

Aaron Ring(Co-founder)Aashish Manglik(Co-founder)Jeff Landau(Chief Executive Officer)inRoland Gendron(Chief Business Officer)inMichelle Zhang(Chief Scientific Officer)in

BoardVineeta Agarwala(Director)in

Co-investorsRA CapitalAndreessen HorowitzMagnetic VenturesOMX VenturesGV (Google Ventures)LoLa Capital Partners+1 more

SynsoryBiosynsorybio.comin𝕏

SynsoryBio develops protein-based drugs that detect their location in the body and activate only at diseased tissue, with applications across cancer and autoimmune conditions.

BiotechHealthtechBoston, US

Elliot Tague(Founder)inNathan Tague(Founder)in

Co-investorsY Combinator

Talusbiosciencetalusbioscience.comin

Talus is a drug discovery company with a proprietary platform that measures and modulates the regulome — the transcription factors, cofactors, and splicing regulators controlling gene expression — in live cells using functional proteomics and AI models.

AI & Machine LearningBiotechDeep Tech

Alex Federation(Ph.D.)Christopher Joyce(MBA)Lindsay Pino(Ph.D.)Michelle BriscoeWill Fondrie(Ph.D.)

Thatchhealththatchhealth.comin𝕏

Thatch is an all-in-one health benefits platform that uses an ICHRA model, letting employers set a tax-free healthcare budget while employees choose their own insurance plans and spend the allowance on health and wellness services via a marketplace and a Thatch Visa debit card.

FintechHealthtechInsurTech

Think Biosciencethinkbioscience.comin

ThinkBioscience develops small-molecule drugs aimed at historically difficult drug targets, using synthetic biology to identify novel mechanisms of biomolecular engagement.

BiotechDeep Tech

Co-investorsAV8 VenturesBuff Gold VenturesCU Healthcare Innovation FundWireframe Ventures

Tilda Researchtilda.bioin

Tilda Research provides AI-powered teammates designed to streamline clinical trial operations for sponsors, contract research organizations, and research sites by automating data management and workflow processes.

AI & Machine LearningHealthtechMedical Devices

Ram Yalamanchili(Founder/CEO)

Co-investors8VCOptum VenturesStorm Ventures

Trestle Biotherapeuticstrestlebio.comin𝕏

Trestle Biotherapeutics develops bioengineered implantable tissues designed to treat end-stage renal disease, aiming to get patients off dialysis and eventually provide replacement organs.

BiotechDeep TechHealthtechMedical DevicesSan Diego, US

Ben Shepherd(Founder)inAlice Chen(Founder)inAlice Chen, PhDBen Shepherd, PhD(CEO)

Co-investorsY Combinator

Trymindedtryminded.com
Zeit Medicalzeitmedical.comin𝕏

Zeit Medical develops a wearable headband with AI-powered sensors that detects strokes in real time and automatically alerts emergency services, targeting patients at high risk for stroke who may be asleep or unable to call for help themselves.

HealthtechMedical DevicesSan Francisco, US

Orestis Vardoulis(Founder)inUrs Naber(Founder)in

Co-investorsCitta CapitalY CombinatorGaingelsSeedToB

Portfolio news

latest coverage across their companies

Frequently asked questions

What stage does Axial VC invest at?
Axial VC invests at the Pre-Seed, Seed, Series A stages.
What is Axial VC's typical check size?
Axial VC typically writes checks of $100K – $5M.
What sectors does Axial VC focus on?
Axial VC focuses on AgTech, AI & Machine Learning, Biotech, FoodTech, Healthtech, Medical Devices.
Where is Axial VC located?
Axial VC is headquartered in San Francisco, US.
Does Axial VC lead rounds?
Axial VC typically participates in rounds rather than leading them.

Co-investors · 4

Susa Ventures

Susa Ventures operates two early-stage technology funds that invest in companies leveraging data, network effects, and economies of scale.

$1M – $5M
UpHonest Capital

UpHonest Capital is a Silicon Valley-based investment firm founded in 2017 that supports cross-border entrepreneurship and investment between China and the United States, and runs media, scout, and incubation programs.

$50K – $1M
Pioneer

Pioneer Fund is a venture capital firm investing in the top Y Combinator startups.

Fifty Years

Fifty Years is a pre-seed and seed focused venture capital firm that backs founders using technology to solve major global problems, and also helps start companies.

$250K – $2M

Firms observed investing alongside Axial VC, from public investor directories. Shared companies are the overlap with Axial VC's recorded portfolio.

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