Axial VC
Venture capitalSan Francisco · Pre-Seed–Series A · 2 people tracked
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Investment thesis
Invests in early-stage life sciences companies, often backing founders when they are no more than an idea.
Team · 2 people
from public directoriesWhat they invest in
from 45 of 53 portfolio companiesBiotech ×36AI & Machine Learning ×21Healthtech ×21Deep Tech ×17Medical Devices ×12Digital Health ×8Wellness & Fitness ×6Consumer ×5
HQs:United States×27Australia×1Switzerland×1United Kingdom×1
Investments · 53 tracked
founders shown can be your intro pathBy year:2025 · 12024 · 22022 · 12020 · 22019 · 17 dated
Adaptyv Bio develops technologies for protein engineering that enable the design and testing of new proteins for applications in medicine, industrial enzymes, and functional materials.
AI & Machine LearningBiotechDeep TechHealthtechLausanne, CH
Julian Englert(Founder)inDaniel Nakhaee-Zadeh Gutierrez(Founder)inRobert KapturinGerard AntouninSam Burnsin
Co-investorsHAWKTAILNeer Venture PartnersRheingau FoundersUnruly CapitalY CombinatorACE & Company+2 more
Aperiam Bio uses computer-vision algorithms to identify "hyperfolding" protein variants with improved expression, solubility, and stability, aiming for order-of-magnitude gains in protein performance.
AI & Machine LearningBiotechDeep TechAustin, US
Austin Cole(CEO & Founder)Guillaume Cottarel(Head of Program)inRussell Durrett(Chief Business Officer)
Co-investorsCivilization Ventures Management, LlcOMX VenturesKdT Ventures
Co-investors8VC
Arda Therapeutics is a drug development company that uses single-cell computational biology to identify and eliminate pathogenic cells as a way to treat chronic diseases.
AI & Machine LearningBiotechDigital HealthLongevityMedical Devices
Adam Freund(Founder & Chief Executive Officer)inRemi-Martin Laberge(Founder & Chief Technology Officer)in
Co-investorsGV (Google Ventures)Alumni VenturesGaingelsIndicator VenturesMana VenturesTwo Sigma Ventures+1 more
Attivare develops AI-powered personalized immunotherapy treatments using a proprietary biomaterial scaffold (ATTImmune) that delivers immune agonists directly to tumor microenvironments, aiming to reduce systemic toxicity in cancer and infectious disease treatment.
AI & Machine LearningBiotechMedical DevicesNatick, US
Edward Doherty(Executive Officer)Jessica McDonough(Director)Joaquim Trias(Executive Officer, Director)
BoardZeshan Muhammedi(Director)
Co-investorsMBX CapitalUlu VenturesEmbark Ventures
Big Hat Bio develops therapeutics under development across multiple programs.
AI & Machine LearningBiotechDeep TechSan Francisco, US
Peyton Greenside(Executive Officer, Director)inMark DePristo(Executive Officer, Director)in
BoardFrancisco Gimenez(Director)inSteve Kafka(Director)Vineeta Agarwala(Director)inRobert Chess(Director)
Co-investors8VCAndreessen HorowitzBOLD LongevityFlucas VenturesGRIDS CapitalAME Cloud Ventures+4 more
BluumBio identifies and deploys naturally occurring enzymes from fungi, trees, and bacteria to remove industrial pollutants from soil, air, and water.
BiotechCleantechHealthtechImpact & Social GoodSan Francisco, US
Katherine French(Founder)in
Co-investorsHAWKTAILOlive Tree CapitalOxonian VenturesY Combinator
Bristle provides digital tools and insights to help people assess and improve their oral health, positioning dental care as a preventive step toward overall wellness.
Digital HealthHealthtechWellness & FitnessSan Francisco, US
David Lin(Founder)inBrian Maurer(Founder)inShivam Patel(Founder)in
Co-investorsR/GA VenturesY CombinatorInitialized Capital
Catena develops a conjugation platform for antibody-drug conjugates (ADCs) and multi-payload conjugates used in oncology for solid tumors.
BiotechDeep TechHealthtechMedical DevicesSan Francisco, US
Marco Lobba(Founder)inMatthew Francis(Founder)in
Co-investorsCivilization Ventures Management, LlcIaso VenturesY CombinatorLongeVCMBX CapitalSocial Impact Capital
CHARM is a biotech company developing a next-generation menin inhibitor for acute myeloid leukemia (AML), designed to address resistance seen with first-generation approaches.
AI & Machine LearningBiotechHealthtechLondon
Lakshyaditya Singh Aithani(Executive Officer, Director)
BoardRishi Gupta(Director)Nihal Sinha(Director)inMuzammil Mansuri(Director)Gary Glick(Director)
Co-investorsF-Prime CapitalNew Enterprise Associates (NEA)OrbiMedSR One Capital ManagementNVentures
ZymeCO creates enzyme-based bio-solutions that accelerate decomposition of organic matter in soil and turf, serving agriculture and golf course management.
AgTechBiotechImpact & Social GoodColorado Springs, US
Thaddaus Huber(Executive Officer, Director)Mark Slavens(CEO)
BoardRik Wehbring(Director)Michael Cantrell(Director)
Concerto Bio generates large-scale ecological datasets on microbial communities and uses them to develop microbe-based consumer health products for applications such as skincare, chronic disease, and nutrition.
AI & Machine LearningBiotechDeep TechCambridge, US
Jared Kehe(Executive Officer, Director)inCheri Ackerman(Executive Officer, Director)inBernardo Cervantes(Executive Officer, Director)inVera Schroeder(Director)
BoardSarah Luppino(Director)in
Co-investorsExcelestar VenturesGolden SeedsHorizons VenturesISVM VenturesMassVentures
Deciduous Therapeutics develops small molecule and immunomodulatory therapies targeting senescent cells to treat age-related diseases including Type 1 diabetes, autoimmunity, and metabolic disorders.
BiotechDigital HealthLongevitySan Francisco, US
Robin Mansukhani(CEO and Co-Founder)inAnil Bhushan(Scientific Founder)in
BoardDylan Morris(Director)in
Co-investorsage1Bold Capital PartnersCornucopian Capital ManagementCRV (Charles River Ventures)Owl CapitalquadraScope Venture Fund+1 more
Delix Therapeutics develops third-generation, non-hallucinogenic neuroplastogens for people with neurological conditions, using a discovery platform to identify novel compounds.
BiotechDigital HealthMedical Devices
Co-investorsArtis VenturesCasa Verde CapitalNoeticOMX VenturesPsyMed VenturesRA Capital+6 more
Enable Medicine builds an integrated biological data platform that organizes and links clinical, spatial, cellular, and molecular data from patients and studies into a unified index to accelerate therapeutic discovery and diagnostics for researchers.
AI & Machine LearningBiotechData & InfrastructureMenlo Park, US
Sunil Bodapati(Executive Officer, Director)inAaron Mayer(Director)in
Co-investorsBreyer CapitalInertia Ventures
The site presents Thai-language promotional content for online slot ("สล็อตเว็บตรง") gambling, listing direct-web slot sites with automatic wallet deposits/withdrawals and hundreds of games.
Co-investorsBantam GroupHyphen Capital
Glyphic Biotechnologies develops ProSE™, a high-throughput de novo protein sequencing technology for analyzing proteomes with single-molecule sensitivity.
BiotechDeep TechBerkeley, US
Daniel Estandian(Founder)inEd Boyden(Founder)Josh Yang(Founder)in
BoardCraig Asher(Director)inJimmy Yun(Director)
Co-investorsArtis VenturesBlack FlagCivilization Ventures Management, LlcFoundersX VenturesHarpoon VenturesLongeVC+5 more
Vancouver-based computational drug discovery company using physics-based molecular simulation to target hard-to-drug proteins.
Co-investorsAngel ForumCognition FundSwan Venture FundWUTIF CapitalYork Angel Investors Inc.
Co-investorsBlue Bear Ventures
Inductive Bio builds AI and machine learning software to accelerate drug discovery for pharmaceutical and biotech researchers, combining computational chemistry with expertise in translating complex drug programs from preclinical to clinical stages.
AI & Machine LearningBiotechDeep TechBrooklyn, US
Josh Haimson(Executive Officer, Director)inBen Birnbaum(Ph.D.)inAlexander Taylor(Ph.D.)in
BoardRohan Ganesh(Director)in
Co-investorsAlleyCorpAndreessen HorowitzCoalition OperatorsLux CapitalObvious VenturesAlley Robotics Ventures+3 more
Infinimmune discovers and develops antibody therapeutics using proprietary sequencing technology and AI-powered optimization.
AI & Machine LearningBiotechMedical Devices
Lance Hepler(Founder)inKatie Pfeiffer(Founder)inMichael Gibbons(Founder)inWyatt McDonnell(Founder)indavid jaffe(Founder)in
Co-investorsCivilization Ventures Management, LlcPlayground Global
Insamo develops an automated platform for drug discovery that designs, synthesizes, and tests cyclic peptides at scale using machine learning and proprietary experimental data.
AI & Machine LearningBiotechDeep TechChippendale, AU
Tim Craven(CEO)inToby Passioura(CSO)inGlen McIntyre(COO)
BoardCOREY GOODMAN(Director)inMATT HERSHENSON(Director)in
Co-investorsCivilization Ventures Management, LlcMRL Ventures FundPlayground GlobalvenBio PartnersvenBio Global Strategic
FODZYME develops an enzyme powder supplement that breaks down FODMAPs in food, particularly fructans found in garlic, onions, and wheat, for people with digestive sensitivities.
BiotechConsumerFoodTechHealthtechWellness & FitnessBoston, US
Anjie Liu(Founder)inDavid Hachuel Gurska(Founder)in
Co-investorsY Combinator
Lyell develops CAR T-cell therapies for cancer patients by leveraging deep expertise in T-cell biology and oncology.
BiotechDeep TechHealthtechMedical DevicesBothell, US
Stan Riddell(Executive Officer)Richard Klausner(Executive Officer, Director, Promoter)Stephen Hill(Executive Officer)inHeather Turner(Executive Officer)inRichard Goold(Executive Officer)inMargo Roberts(Executive Officer)
Co-investorsARCH Venture PartnersForesite CapitalvenBio Partners8VC
Machine learning and data platform for understanding how diseases fight back and resist therapies
David Li(Founder)in
Nuanced Health develops healthcare solutions, though the specific product focus is not detailed on this team page.
AI & Machine LearningBiotechDeep TechHealthtechLos Angeles, US
Sarkis Mazmanian(Co-Founder)inYan Yang(Chief Scientific Officer)in
Co-investorsFREEFLOWOpen Field Capital
Wellness & FitnessLos Angeles, US
Kyle Pierce(Executive Officer, Director)inMorgan Hewett(Executive Officer, Director)
Co-investorsBread And Butter Ventures, LlcTechstarsBread Butter VenturesBright VenturesCollab CapitalM13+1 more
Papa is a platform that connects older adults and families with trained companion caregivers for in-home companionship and support services.
ConsumerDigital HealthHealthtechSocialWellness & FitnessMiami, US
Andrew Parker(Founder/CEO)inAlfredo Vaamonde(Co-Founder)inAndrew(CEO)inCharles Hector(Executive Officer)
BoardByron Ling(Director)Fatima Husain(Director)
Co-investorsComcast VenturesIntegra GroupeMagnify VenturesSoftBank Vision FundThe Chernin Group (TCG Crypto)Y Combinator+2 more
Parallel Bio develops human immune organoids and computational tools to predict drug efficacy across diverse patient populations, replacing animal testing in drug discovery.
AI & Machine LearningBiotechDeep TechHealthtechSan Francisco, US
Robert DiFazio(Founder)inJuliana Hilliard(Founder)in
Co-investorsAIX VenturesBreakout VenturesHumba VenturesImmeasurableJulian CapitalMetaplanet+5 more
Parallel Health offers a skincare product line addressing aging through microbiome science, including peptide creams and cleansers designed to target the hallmarks of skin aging.
BiotechConsumerDigital HealthDirect to ConsumerHealthtechWellness & Fitness
Co-investorsFirst In VenturesHyphen Capital
Potion creates automation and workflow solutions for beauty and personal care companies to reduce time spent on repetitive tasks.
AI & Machine LearningConsumerEnterprise SoftwareMarketing TechSaaSSan Francisco, US
Yahya Syed(Founder)inHejab Malik(Founder)inAlex Stec(Founder)in
Co-investorsHAWKTAILY Combinator
Reference Medicine supplies biological specimens to researchers and diagnostics developers working on cancer diagnostic tools.
AI & Machine LearningB2B MarketplacesBiotechDigital HealthHealthtechMedical Devices
Co-investorsMetaplanet
Replay develops gene therapies for patients with rare genetic diseases.
BiotechHealthtechLongevity
Lachlan MacKinnon(CEO and Founder)Adrian Woolfson(Founder)Robert Coffin(Executive Chairman)Maria Castner-Miller(General Counsel)inRenata Martin(VP & Head of Gene Therapy)inSaurabh Sharma(VP & Head of CMC)
Co-investorsArtis VenturesOMX VenturesSolari Capital
Rubi uses enzymes to capture CO2 and convert it into cellulose, producing textile materials through a carbon-negative process that avoids extraction and biodegrades at end-of-life.
Advanced ManufacturingCleantechClimate TechNew MaterialsAlameda, US
Neeka Mashouf(Executive Officer, Director)inLeila Mashouf(Executive Officer, Director)in
BoardDaria Hosseinyoun(Director)Rohini Finch(Director)
Co-investorsCapitalXClimacticCollaborative FundDarco CapitalNecessary VenturesTalis Capital
Seranova is a biotech company that combines REAP autoantibody profiling with clinically linked patient cohorts to identify naturally occurring protective autoantibodies against specific extracellular targets and translate those protective associations into therapeutic hypotheses.
AI & Machine LearningBiotechDeep TechNew Haven, US
Aaron Ring(Manager)inBeatrice McQueen(Executive Officer)
BoardJim Tananbaum(Manager)
Co-investorsARCH Venture Partners
Simcha is a biotechnology company developing new cancer medicines based on immune biology research.
BiotechHealthtechNew Haven, US
Aaron Ring(Executive Officer, Director)inBeatrice McQueen(Chief Operating Officer)inSanuj Ravindran(Chief Executive Officer)Jeremy Barton(Chief Medical Director)Hirdesh Uppal(Senior Vice President Translational Research and Development Sciences)Joseph Catino(Executive Officer)
Co-investorsConnecticut InnovationsPfizer Venture InvestmentsSR One Capital ManagementBiotechnology Value FundRock Springs CapitalSamsara BioCapital
Stately Bio develops stem cell-derived regenerative and cell therapies using a machine learning platform that measures cell identity, behavior, and maturation directly from live-cell, label-free imaging.
AI & Machine LearningBiotechMedical Devices
Frank Li(Founder & CEO)Christian Elabd, PhD(Head of Biology)
Co-investorsAIX VenturesFoothill VenturesMitsui Global InvestmentBoxOne VenturesCaffeinated CapitalDimension Capital+1 more
Stipple Bio develops targeted oncology therapies that act on tumor-specific cell surface epitopes to expand druggable targets and improve therapeutic index for cancer patients.
BiotechHealthtechCambridge, US
Aaron Ring(Co-founder)inAashish Manglik(Co-founder)inJeff Landau(Chief Executive Officer)inRoland Gendron(Chief Business Officer)inMichelle Zhang(Chief Scientific Officer)in
BoardVineeta Agarwala(Director)in
Co-investorsRA CapitalAndreessen HorowitzMagnetic VenturesOMX VenturesGV (Google Ventures)LoLa Capital Partners+1 more
SynsoryBio develops protein-based drugs that detect their location in the body and activate only at diseased tissue, with applications across cancer and autoimmune conditions.
BiotechHealthtechBoston, US
Elliot Tague(Founder)inNathan Tague(Founder)in
Co-investorsY Combinator
Talus is a drug discovery company with a proprietary platform that measures and modulates the regulome — the transcription factors, cofactors, and splicing regulators controlling gene expression — in live cells using functional proteomics and AI models.
AI & Machine LearningBiotechDeep Tech
Alex Federation(Ph.D.)Christopher Joyce(MBA)Lindsay Pino(Ph.D.)Michelle BriscoeWill Fondrie(Ph.D.)
Think Bioscience develops new medicines for diseases with limited treatment options through synthetic biology and computational chemistry.
BiotechDeep Tech
Co-investorsAV8 VenturesBuff Gold VenturesCU Healthcare Innovation FundWireframe Ventures
Tilda Research provides AI-powered teammates designed to streamline clinical trial operations for sponsors, contract research organizations, and research sites by automating data management and workflow processes.
AI & Machine LearningHealthtechMedical Devices
Ram Yalamanchili(Founder/CEO)in
Co-investors8VCOptum VenturesStorm Ventures
Trestle Biotherapeutics develops bioengineered implantable tissues designed to treat end-stage renal disease, aiming to get patients off dialysis and eventually provide replacement organs.
BiotechDeep TechHealthtechMedical DevicesSan Diego, US
Ben Shepherd(Founder)inAlice Chen(Founder)inAlice Chen, PhD(Co-founder and Chief Scientific Officer)inBen Shepherd, PhD(Co-Founder and Chief Executive Officer)
Co-investorsY CombinatorDraper Associates
Zeit Medical develops a wearable headband with AI-powered sensors that detects strokes in real time and automatically alerts emergency services, targeting patients at high risk for stroke who may be asleep or unable to call for help themselves.
HealthtechMedical DevicesSan Francisco, US
Orestis Vardoulis(Founder)inUrs Naber(Founder)in
Co-investorsCitta CapitalFoundersY CombinatorGaingelsSeedToBTamar Capital
Portfolio news
latest coverage across their companiesLyell · investing.com · Aug 9, 2026
Papa · simplywall.st · Jul 18, 2026
Stipple Bio · bioxconomy.com · Apr 10, 2026
Parallel Bio · genengnews.com · Apr 2, 2026
Rubi Laboratories · bizjournals.com · Mar 17, 2026
Adaptyv · ggba.swiss · Oct 27, 2025
Arda Therapeutics · nasdaqprivatemarket.com · Oct 21, 2025
Delix · ucdavis.edu · Sep 10, 2025
Frequently asked questions
- What stage does Axial VC invest at?
- Axial VC invests at the Pre-Seed, Seed, Series A stages.
- What is Axial VC's typical check size?
- Axial VC typically writes checks of $100K – $5M.
- What sectors does Axial VC focus on?
- Axial VC focuses on AgTech, AI & Machine Learning, Biotech, FoodTech, Healthtech, Medical Devices.
- Where is Axial VC located?
- Axial VC is headquartered in San Francisco, US.
- Does Axial VC lead rounds?
- Axial VC typically participates in rounds rather than leading them.
Co-investors · 4
Susa Ventures operates two early-stage technology funds that invest in companies leveraging data, network effects, and economies of scale.
UpHonest Capital is a Silicon Valley-based investment firm founded in 2017 that supports cross-border entrepreneurship and investment between China and the United States, and runs media, scout, and incubation programs.
Pioneer Fund is a venture capital firm investing in the top Y Combinator startups.
Fifty Years (50Y) is a pre-seed and seed-focused venture capital firm that backs founders using technology to solve major global problems, and also helps start companies.
Firms observed investing alongside Axial VC, from public investor directories. Shared companies are the overlap with Axial VC's recorded portfolio.
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