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Dementia Discovery Fund

Venture capital

London · Seed–Late Stage · 80 people tracked

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Investment thesis

SV Health Investors backs diverse entrepreneurs building breakthrough life sciences companies and treatments, aiming to transform healthcare one investment at a time. Its platform spans all healthcare sectors and stages through three dedicated teams: therapeutics/biotechnology (including a dedicated dementia strategy, the Dementia Discovery Fund), healthcare growth equity, and medtech. With more than 50 investment professionals and operating partners across Boston and London and a roughly 30-year track record, the firm seeks innovative therapeutic breakthroughs, provides growth capital and liquidity to healthcare industry leaders, and supports compelling medtech teams and technologies. It emphasizes diversity, including under-represented founders, as a driver of success.

Source: firm website, verified Sep 26, 2026.

Stage
Seed–Late Stage
HQ
London, GB
Instruments
Equity
AUM
$4B
Tracked investments
44
IPOs
1
Acquisitions
2

Team · 80 people

from the firm's website
A.J. Rossi· Partner
Greg Madden· Managing Partner
Jamil M. Beg· Partner
Kate Bingham· Managing Partner

Managing Partner at SV Health Investors and chair of Alchemab's board of directors.

Michael Balmuth· Managing Partner
Paul LaViolette· Managing Partner
Tom Flynn· Managing Partner
Charles Dunn· Principal
Dirk Landgraf· Principal
Barbara Tate· Venture Partner
Brett Haumann· Venture Partner
Charles Large· Venture Partner
Damian Crowther· Venture Partner
David Guyer· Venture Partner
David Reynolds· Venture Partner
Iain Kilty· Venture Partner
James Summers· Venture Partner
Joanna Wolak· Venture Partner
Kevin Pojasek· Venture Partner
Luke Devey· Venture Partner
Lynne Hughes· Venture Partner
Ravi Rao· Venture Partner
Ray Jupp· Venture Partner
Susan Hill· Venture Partner
Tetsu Maruyama· Venture Partner
Alex Badamchi-Zadeh· Vice President
Ali Jazayeri· Operating Partner
Andrew Cappetta· Vice President
Anne-Marie Garraway· Executive Assistant
Ashley Pulcini· Executive Assistant
Brent Faduski· Chief Financial Officer, Chief Compliance Officer and Partner
Bryce Hewitt· Finance Associate
Celina Lee· Gradiant in Residence
Ceri Davies· DDF SAB Member
Dan Burgess· Operating Partner
Darshi Singh· Head of IT
Eugene Hill· Chairman
Fiona Elwood· DDF SAB Member
Georgina Ewels· Director, Investor Relations
Gloria Lau· Junior Fund Controller
Greg Dulgarian· Controller
Hannah Maunder· Senior Associate, Investor Relations
Inna Walker· Business Support and Office Coordinator
Jean Rivera Irizarry· Associate
Jodie O'Neill· Accountant
John Lyons· DDF SAB Member
Jonathan Mott· Chief Compliance Officer
Kate McCabe· Finance Director
Kelly DeKeyser· Executive in Residence
Kerry Spellman· Executive Assistant
Lennart Spindler· Associate
Luke Johnson· Operating Partner
Maria Carrillo· DDF SAB Member
Michael Heneka· Scientific Advisor
Michael Ugwueke· President & CEO, Methodist Le Bonheur Healthcare (Growth Fund Advisory Board)
Nicole Cox· Executive Assistant
Nikki Hecht· Executive Assistant
Niranjan Bose· DDF SAB Member
Pam Simpkins· Growth Fund Advisory Board
Rana Al-Hallaq· DDF SAB Member
Richard Hargreaves· DDF SAB Member
Roopam Chandaria· Financial Controller
Ruth McKernan· Operating Partner
Stacey Jolin· Executive Assistant
Susan Kohlhaas· DDF SAB Member
Tom Policelli· Executive in Residence
Vineela Kanagala· Senior Associate

What they invest in

from 35 of 44 portfolio companies

Biotech ×29Healthtech ×22Deep Tech ×13Medical Devices ×9AI & Machine Learning ×7Digital Health ×6Data & Infrastructure ×5Longevity ×3

HQs:United States×17United Kingdom×5Australia×1

Who they back

founder profiles across 9 portfolio companies
56%
solo founders
5 of 9 mapped founding teams
8%
repeat founders
of 12 founders with career history

Founding team size:solo founder×52 founders×34+ founders×1

Where their founders studiedfrom 11 founders with education data

University of Chicago ×2

What their founders studiedfrom 10 founders with field-of-study data

Life Sciences ×5Computer Science ×2Medicine ×2

Where their founders worked beforefrom 12 founders with career history

Alzheimer's Research UK ×2Pfizer ×2Rigimmune ×2UCL ×2

Investments · 44 tracked

founders shown can be your intro path

By year:2025 · 22024 · 22023 · 72022 · 12021 · 113 dated

Bicyclebicycletherapeutics.comin𝕏NASDAQ: BCYCMay 2024

Bicycle Therapeutics develops precision-guided therapeutics based on its proprietary bicyclic peptide (Bicycle) technology, designed to penetrate deep into tissues and target intractable solid tumor cancers.

BiotechHealthtechCambridge, GB

Gregory Winter(Director)inKEVIN LEE(Executive Officer, Director)inNIGEL CROCKETT(Executive Officer)inNICHOLAS KEEN(Executive Officer)SANTIAGO ARROYO(Executive Officer)inMICHAEL HANNAY(Executive Officer)

Co-investorsAhren Innovation CapitalAstellas Venture Management LLCCambridge Innovation CapitalLongwood FundRidgeback CapitalSR One Capital Management+4 more

Cerevancecerevance.comin𝕏✓ verified

Cerevance develops precision novel therapeutics for central nervous system disorders, particularly neurodegenerative diseases, using its proprietary NETSseq platform and machine learning to identify targets from an extensive collection of human brain tissue samples.

AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesBoston, US

Craig Thompson(Chief Executive Officer)inSagar Vaidya(Chief Medical Officer)inCarrie Ann Cook(Chief Business Officer)Mark Carlton(Chief Scientific Officer)inOttavio V. Vitolo(Chief Medical Officer)in

Co-investorsForesite CapitalGV (Google Ventures)SV Life SciencesDementia DiscoveryDolby Family VenturesLightstone Ventures+3 more

cumulus-neurosciencecumulusneuro.comin✓ verified

NeuLogiq is a research platform for clinical trials that integrates tablet-based cognitive assessments, EEG monitoring, and real-world behavioral data to measure brain function changes.

AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesBelfast, GB

Brian Murphy(Co-Founder & CSO)inTina(CEO)

Co-investorsClarendon Fund Managers Ltd.LifeArc Ventures

Harness Therapeutics Ltdharnesstx.comin✓ verified

Harness Therapeutics develops disease-modifying precision therapies for hard-to-treat neurodegenerative diseases through controlled modulation of CNS targets.

BiotechHealthtech

Jan Thirkettle(CEO Director)in

Co-investorsEpidarex CapitalOno Venture Investment, Inc.SV Health Investors

Dualitas Therapeuticsdualitastx.cominJul 2025SEC filingmedium confidence

Dualitas Therapeutics develops bispecific antibody therapies that pair a proprietary proximity engager arm with an antibody against a therapeutic target, using its DualScreen discovery engine to identify synergistic target combinations.

BiotechDeep TechSouth San Francisco, US

Greg Lazar, Ph.D.(Co-Founder and Chief Scientific Officer)Forbes Huang(Co-Founder, Chief Operating Officer & Chief Business Officer)inGreg Lazar(Co-Founder & Chief Scientific Officer)inRichard Murray(Executive Officer, Director)Karim Dabbagh(Chief Executive Officer, Board Member)inKarim Dabbagh, Ph.D.(Chief Executive Officer, Board Member)in

Board seatNeil Weir· per SEC Form D · $66.6M raise · filed Nov 2025

Co-investorsQiming Venture PartnersSV Health InvestorsVersant VenturesAlexandriaQiming HealthcareQiming Venture Partners USA

Alchemabalchemab.comin𝕏

Alchemab operates a platform that identifies novel drug targets and therapeutics by analyzing patient antibody repertoires using deep B cell sequencing and computational analysis of samples from disease-resilient individuals.

AI & Machine LearningBiotechDeep TechHealthtech

Jane Osbourn(Chief Executive Officer)

Co-investorsRA CapitalSV Health InvestorsDCVC BioLightstone VenturesOno Venture Investment, Inc.British Business Bank+2 more

Amphista Therapeuticsamphista.comin𝕏Dec 2022

Amphista Therapeutics develops next-generation targeted protein degradation (TPD) medicines using its proprietary Targeted Glue technology, which is engineered to selectively trigger the destruction of disease-causing proteins.

BiotechCambridge, GB

Louise Modis(Chief Executive Officer)inMartin Pass(Chief Development Officer)inGiles Brown(Executive VP Drug Discovery)in

Co-investorsAdvent Life SciencesNovartis Venture FundSV Health InvestorsEuropean Investment FundForbionGilde Healthcare+2 more

Artios Pharmaartios.comin𝕏

Artios develops DNA damage response (DDR)-based medicines targeting patients with high unmet need cancers.

BiotechHealthtechMedical Devices

Co-investorsAndera PartnersM VenturesNovartis Venture FundPfizer Venture InvestmentsRA CapitalSofinnova Partners+3 more

AstronauTX Ltdastronautx.bioin

AstronauTx is a biotechnology company focused on drug discovery and development for neurodegenerative and neuroinflammatory diseases, working across small molecules and biologics.

BiotechDeep TechHealthtechLongevityMedical Devices

Jane Rhodes(Chief Executive Officer)inMagnus Ivarsson(Chief Scientific Officer)inHannah Pearce(Chief Operating Officer)inMichelle L. Mellion(Chief Medical Officer)in

Co-investorsMPM BioImpactNovartis Venture FundSV Health InvestorsUCL Technology FundAlbionVC

Carawaycarawaytx.comin𝕏acquired by Merck

Caraway Therapeutics was a preclinical biopharmaceutical company developing small-molecule therapies modulating lysosomal function to treat neurodegenerative and rare diseases.

BiotechHealthtech

Co-investorsEisai Innovation, Inc.McCarthy CapitalMRL Ventures FundSV Health InvestorsAbbVieBridge Investments+9 more

Centauri Health Solutionscentaurihs.comin𝕏

Centauri provides data-driven technology and services for U.S. health plans and health systems, turning fragmented clinical data into analytics used for risk adjustment, care coordination, quality optimization, and clinical data exchange.

Data & InfrastructureDigital HealthHealthtech

Mike McNelis(Founder)in

Co-investorsABRY PartnersSilversmith Capital PartnersSV Health Investors

Cumulus Labscumuluslabs.ioin𝕏

Cumulus Labs provides an inference platform that consolidates production AI infrastructure (routing, caching, observability, evaluation, fine-tuning, and runtime) into a single API.

AI & Machine LearningCloud ComputingData & InfrastructureDeveloper ToolsEnterprise SoftwareSan Francisco, US

Veer Shah(Founder)in

Co-investorsY CombinatorInvesting Women AngelsValor Equity PartnersBatch VenturesFounders FactoryOurCrowd+1 more

Enara Bioenarabio.comin𝕏

Enara Bio discovers and validates Dark Antigens from non-coding genomic regions to identify novel cancer targets, and develops first-in-class bispecific T-cell engagers against these targets through its EnTiCE platform.

BiotechDeep TechMedical Devices

George Kassiotis(Co-founder)Drew Pardoll(Co-founder)Houman Ashrafian(Co-founder)in

Co-investorsRA CapitalSV Health InvestorsPfizer VenturesSamsara BioCapitalM VenturesPfizer Venture Investments

EndLyz Therapeuticsendlyz.comin

Endlyz develops small-molecule disease-modifying therapeutics targeting the ATP13A2 and ATP10B lysosomal transporters to restore endo-lysosomal function and counter neurodegeneration.

BiotechDeep TechBoston, US

Joanna Wolak(Executive Officer, Director)inJonathan Behr(Director)John Gustofson(Director)Damian Crowther(Director)Zaven Kaprielian(Executive Officer, Director)

BoardLaurence Barker(Director)

Co-investorsOxford Science Enterprises

Evidation Healthevidation.comin𝕏

Evidation collects and analyzes real-world health data from millions of community members to enable clinical research and health programs across various medical conditions.

BiotechData & InfrastructureDigital HealthHealthtechSan Francisco, US

Christine Lemke(Executive Officer, Director)inDeborah Kilpatrick(Executive Officer, Director)Leslie Oley Wilberforcein

BoardDavid Fleshman(Director)Rowan Chapman(Director)in

Co-investorsAsset Management CompanyB Capital GroupB4 CapitalCross Creek AdvisorsFresco CapitalG Squared+6 more

Leitersleiters.comin

Leiters Health is an FDA-registered 503B outsourcing facility that produces sterile compounded preparations for hospitals, surgery centers, and ophthalmic use.

BiotechHealthtechMedical DevicesDenver, US

Co-investorsCorewell Health VenturesEscalate Capital PartnersFrazier Healthcare PartnersH.I.G. CapitalH.I.G. HealthBridge PartnersKaiser Permanente Ventures+3 more

LoQus23loqus23.cominNov 2021

LoQus23 Therapeutics is a drug discovery company developing treatments for triplet repeat expansion diseases such as Huntington's disease, focused on preclinical CNS and neuroscience research.

BiotechDeep TechCambridge, GB

David Reynolds(Co-founder & CEO)inCaroline Benn(Co-founder & CSO)in

Co-investorsNovartis Venture FundSV Health InvestorsForbion

Montara Therapeuticsmontaratx.comin

Montara is a biotech company developing small-molecule therapeutics focused on neurodegeneration and diseases such as Alzheimer's.

AI & Machine LearningBiotechDeep TechSan Francisco, US

Kevan Shokat(Co-Scientific Founder & Chairman of the SAB)Thomas Südhof(Co-Scientific Founder & SAB Member)Seth Stratton(Director)Dirk Langdorf(Director)Nicholas Hertz(Executive Officer, Director)

Co-investorsBEVCDolby Family VenturesSV Health InvestorsTwo Bear CapitalKdT Ventures

Nimbus Therapeuticsnimbustx.comin

Nimbus Therapeutics is a biotechnology company that designs precision small molecule medicines using a computational, multidisciplinary drug discovery approach.

AI & Machine LearningBiotechDeep TechHealthtech

Co-investorsAccess BiotechnologyAtlas VentureBain Capital Life SciencesGV (Google Ventures)Lightstone VenturesPfizer Venture Investments+4 more

Nitrase Therapeuticsnitrasetx.comin

Nitrase Therapeutics is a clinical-stage biopharmaceutical company using its NITROME platform to develop therapeutics based on nitrases, a class of enzymes it discovered that drive protein nitration.

BiotechHealthtechLongevity

Irene Griswold-Prenner(Founder & Chief Executive Officer)in

Co-investorsMission BiocapitalSofinnova PartnersSV Health InvestorsAbbVieMission Bay Capital

NRG Therapeuticsnrgtherapeutics.cominSep 2025 · $67M

NRG Therapeutics is a biotech company developing small-molecule drugs targeting the mitochondrial permeability transition pore (mPTP) for neurodegenerative diseases such as ALS and Parkinson's.

BiotechHealthtechLongevity

Neil Miller(CEO)inRichard Rutter(CSO)inGrant Hawthorne(COO)inClaus Sundgreen(Chief Medical Officer)inPaul Thompson(CDO)in

BoardJonathan Savidge(Independent Non Executive Chair)

Co-investorsCriteria Bio VenturesNovartis Venture FundSV Health InvestorsBritish Business BankM VenturesOmega Funds

Pulmocidepulmocide.comin

Pulmocide is a biopharmaceutical company developing inhaled therapies for difficult-to-treat respiratory diseases, currently focused on respiratory fungal infections such as pulmonary aspergillosis.

BiotechHealthtech

Pete Strong(Co-founder)Garth Rapeport(Co-founder)inKazuhiro Ito(Co-founder)inJohn Murray(Co-founder)inDavid Mantusin

Co-investorsAdjuvant CapitalAsahi Kasei Corporate Venture CapitalF-Prime CapitalJeito CapitalLongwood FundSR One Capital Management+4 more

Quralisquralis.comin𝕏Mar 2023

QurAlis develops precision therapies for amyotrophic lateral sclerosis (ALS) and related neurodegenerative diseases by targeting specific disease-causing genetic drivers and molecular mechanisms.

BiotechDeep TechMedical DevicesCambridge, US

Kevin Eggan(Co-founder)inRoet(Co-founder)Woolf(Co-founder)Kasper Roet(Director, Executive Officer, Promoter)inShafique Virani(Executive Officer)inJason Brown(Mr. Brown is the Chief Financial Officer of the Issuer.)in

Co-investorsDolby Family VenturesDroia VenturesInkefMC Healthcare VenturesMission BiocapitalMitsui Global Investment+7 more

Ribometrixribometrix.com

BiotechGreenville, US

Kevin Weeks(Executive Officer, Director)Katherine Warner(Executive Officer)Joshua Resnick(Director)Michael Solomon(Director)John Gustofson(Director)

BoardMike Dial(Director)in

Co-investorsHatteras Venture PartnersIllumina VenturesM VenturesMC Healthcare VenturesPappas CapitalSV Health Investors+2 more

Rondo Therapeuticsrondotx.comin

Rondo Therapeutics is an immuno-oncology biopharmaceutical company developing bispecific/multispecific antibody therapeutics designed for tumor-selective targeting to treat solid tumors while sparing healthy tissue.

BiotechHealthtech

Shelley Force Aldred(Co-Founder & Chief Executive Officer)inNathan Trinklein(Co-Founder, President & CSO)inKatherine(Chief Development Officer)Thomas(Chief Medical Officer)

Co-investorsCanaan PartnersRed Tree VentureSV Health InvestorsJohnson & Johnson Innovation – JJDCNovo Holdings

Sitryxsitryx.comin𝕏

Sitryx is a biotechnology company, founded in 2018, developing therapeutics with a focus on immunometabolism.

BiotechDeep TechHealthtech

Co-investorsLongwood FundOxford Science EnterprisesSofinnova PartnersSV Health Investors

Sudo Biosudobio.comFeb 2024

Sudo Biosciences develops small molecule therapeutics for neurological and immune-mediated inflammatory conditions.

BiotechHealthtechMedical DevicesMenlo Park, US

Jim Bristol(Director)Daniel Estes(Director)inScott Byrd(Executive Officer, Director)in

Co-investorsFrazier Life SciencesMonograph Capital PartnersPICUS CAPITALSanofi VenturesSV Health InvestorsFrazier Healthcare Partners+2 more

Therini Biotherinibio.cominApr 2023 · $36M

Therini Bio is a biotechnology company developing fibrin-targeting therapeutics to treat neurological and ophthalmological diseases, leveraging scientific discoveries in neurovascular and neuroimmune mechanisms of disease.

BiotechDigital HealthHealthtechMedical DevicesSacramento, US

Katerina Akassoglou(Scientific Founder, Director of the Center for Neurovascular Brain Immunology and Professor of Neurology at UCSF and Gladstone Institutes)inKaterina Akassoglou, PhD(Scientific Founder)Leslie Schulze(Executive Officer)Tara Nickerson(Executive Officer, Director)in

BoardOlga Danilchanka(Director)inLaia Crespo-Martin(Director)

Co-investorsMRL Ventures FundSanofi VenturesSV Health InvestorsAngelini VenturesDolby Family VenturesMitsui Global Investment+2 more

TRexBiotrex.bioin

TRexBio develops biologic medicines targeting inflammation in autoimmune and inflammatory diseases by decoding human tissue biology.

AI & Machine LearningBiotechDeep TechHealthtech

Johnston Erwin(Chief Executive Officer)Ali Zarrin(Chief Scientific Officer)

Co-investorsAvego BioScience CapitalDelos CapitalPfizer Venture InvestmentsSV Health InvestorsAgent CapitalPolaris Partners

Violetvioletlabs.cominMay 2023 · $10.6M

Violet Labs builds software tools for engineers designing and building physical products across industries including aerospace, defense, robotics, and energy.

Data & InfrastructureDeveloper ToolsEnterprise SoftwareHardware

Lucy Hoag(Founder)in

Co-investorsFelicis VenturesMaC Venture CapitalMairs & Power VCV1 VCHopelabNorthwell Holdings+4 more

Violetviolet.org.auMay 2023 · $10.6M

Violet provides free, personalised support for Australian families navigating end-of-life care, combining human connection and technology to offer practical guidance, emotional support, and tools for important conversations.

Digital HealthFintechHealthtechImpact & Social GoodMental HealthHaymarket, AU

BoardKate Carnell(Chairperson)

Co-investorsTechstarsHopelabNorthwell HoldingsOno Venture Investment, Inc.SemperVirens Venture CapitalThe Venture Collective+1 more

Violetjoinviolet.cominMay 2023 · $10.6M

Violet provides healthcare organizations with data analytics and tools to measure and improve their ability to deliver person-centered care that considers patients' individual preferences, identities, and experiences.

Data & InfrastructureDigital HealthHealthtechNew York City, US

Gaurang Choksi(CEO and Founder)inScott Zaloom(Head of Operations)inDr. Kay Nikiforova(Head of Clinical & Research)inEliot Kristan(Head of Engineering)in

Co-investorsSeae VenturesSemperVirens Venture CapitalThe Venture CollectiveW Health Ventures Gp LlcHopelabNorthwell Holdings+2 more

Violetviolet.ioin𝕏May 2023 · $10.6M

Violet provides a unified API for commerce infrastructure that simplifies checkout, catalog management, and order processing for platforms and marketplaces serving multiple merchants.

B2B MarketplacesE-commerceSaaSSeattle, US

Brandon Schulz(Founder)inRhen Zabel(Executive Officer, Director, Promoter)Adam Dreiblatt(Director)

Co-investorsAlumni VenturesSeaChangeHopelabNorthwell HoldingsOno Venture Investment, Inc.Red Sea Ventures+4 more

Violet Therapeutics, Inc.violettx.comMay 2023 · $10.6M

Violet is a therapeutics company developing small molecule treatments for central nervous system diseases, using its proprietary C-to-C Engine platform to identify disease-relevant cell-to-cell interactions.

BiotechDeep TechCambridge, US

Co-investorsDementia DiscoveryOno Venture Investment, Inc.SV Health InvestorsUTEC

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

AeroCare Holdings, Inc.American WellDualitasEyeBioMisonixNitrome BiosciencesNordic Consulting PartnersSchweiger DermatologySpectrum Professional ServicesXimedica

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

Exits · 3

1 IPOs · 2 acquisitions

BicycleNASDAQ: BCYCCarawayacq. by MerckEyeBioacq. by Merck

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has Dementia Discovery Fund made?
Dementia Discovery Fund has 44 tracked investments, 3 of which have exited, including 2 dated in the last 24 months.
What stage does Dementia Discovery Fund invest at?
Dementia Discovery Fund invests at the Seed, Series A, Series B, Series C, Growth, Late Stage stages.
What sectors does Dementia Discovery Fund focus on?
Dementia Discovery Fund focuses on Biotech, Digital Health, Healthtech, IoT, Longevity, Medical Devices.
Where is Dementia Discovery Fund located?
Dementia Discovery Fund is headquartered in London, GB.
Does Dementia Discovery Fund lead rounds?
Dementia Discovery Fund has led 7 of the 12 rounds where its role is on record.
Who does Dementia Discovery Fund co-invest with?
Dementia Discovery Fund most often shares deals with SV Health Investors, Pfizer Venture Investments, RA Capital, among 62 tracked co-investors.

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