Big Brain Holdings

Upexi is a Solana-focused treasury company that acquires, holds, and stakes SOL tokens to give investors digital asset exposure through a publicly traded equity security (UPXI).

Crypto & Web3Fintech

Allan Marshall(Chief Executive Officer)

Co-investorsWhite Star CapitalGSR

CrossCurve is a cross-chain DeFi protocol built around its Cross-chain Data Protocol (CDP), a messaging and transport layer for transferring data and liquidity between blockchains, supporting products such as a cross-chain bridge, liquidity protocol, and DEX.

Crypto & Web3Developer ToolsFintech

Boris Povar(Founder)in

Co-investorsDraper AssociatesFenbushi CapitalGBV CapitalMarshland CapitalBitDAOMantle Network

decent.land builds onchain data infrastructure — an "onchain data center" for storing, verifying, and computing with blockchain data at scale, secured by Arweave and HyperBEAM.

Crypto & Web3Data & InfrastructureDeveloper Tools

Co-investorsForesight VenturesLD CapitalTsingTech Ventures

Eywa provides a MetaLayer and API for building in DeFi, offering a single integration for cross-chain routing, deep liquidity access, and automated on-chain operations across EVM and non-EVM networks with gasless execution.

Crypto & Web3Developer ToolsFintech

Co-investorsFenbushi CapitalGBV CapitalMarshland CapitalAfford.CapitalMulana Capital

Helika builds Helika Evolve, a brand-safe AI character platform that lets IP owners deploy interactive characters trained on their approved content to engage fans in real time across Discord, web, social, and community channels.

AI & Machine LearningGamingMarketing Tech

Anton(Founder & CEO)Ilya(CPO)

Co-investorsDiagramPantera CapitalBuilder CapitalFenbushi CapitalSparkle VenturesFermion

Aethir operates a distributed cloud compute platform providing enterprise-grade GPU resources for AI model training, fine-tuning, inference, and low-latency cloud gaming.

AI & Machine LearningCloud ComputingCrypto & Web3

Co-investorsAndromeda CapitalAnimoca BrandsBuilder CapitalCVP NoLimitImpossible FinanceInception Capital (ex OP Crypto)+8 more

Agility Robotics develops and deploys humanoid robots for warehouse automation and logistics operations.

AI & Machine LearningHardwareLogistics & Supply ChainRoboticsSalem, US

Jonathan Hurst(Co-founder & Chief Robot Officer)inDamion Shelton(Co-Founder & Chairman of the Board)in

BoardBruce Leak(Director)inMatthew Ocko(Director)in

Co-investorsDCVC (Data Collective)HARPER COURT VENTURESManhattan Venture PartnersMFV PartnersNVenturesPlayground Global+5 more

AheadComputing develops high-performance 64-bit RISC-V application processor cores designed to maximize per-core CPU performance for AI, cloud, client, mobile, and edge workloads.

AI & Machine LearningDeep TechSemiconductorsBeaverton, US

Debbie Marr(Founder)inJonathan Pearce(Founder)inSrikanth Srinivasan(Founder)Deborah Marr(Executive Officer, Director)

BoardGreg Reichow(Director)Jim Keller(Director)

Co-investorsCambium CapitalEclipse VenturesMESHTrousdale Ventures

Ritual is a research lab building a blockchain infrastructure for autonomous AI agents, providing native primitives for agent identity, privacy, settlement, scheduling, and coordination.

AI & Machine LearningCrypto & Web3Deep Tech

Co-investorsArchetypeBollinger Investment GroupEdessa CapitalHypersphere VenturesLvna CapitalMH Ventures+1 more

Akave provides an S3-compatible object storage cloud with usage-based pricing, zero egress fees, immutability, and cryptographic access controls, positioned as a lower-cost alternative to hyperscalers like AWS.

AI & Machine LearningCloud ComputingData & Infrastructure

Co-investorsCVP NoLimitNo Limit Holdings (NLH)

Ambient provides verifiable AI inference on an open network, running open models such as Kimi K2.7 Code and GLM 5.2 through OpenAI- and Anthropic-compatible API endpoints.

AI & Machine LearningCloud ComputingDeveloper Tools

Antigma builds Ante, a Rust-based agent runtime that runs AI coding agents locally through a single self-contained binary with built-in llama.cpp integration for offline model inference.

AI & Machine LearningDeep TechDeveloper Tools

Apptronik builds humanoid robots designed to perform repetitive, physically taxing, and dangerous tasks in warehousing and manufacturing environments, aiming to free workers for higher-value activities.

Advanced ManufacturingAI & Machine LearningHardwareRoboticsAustin, US

Jeff Cardenas(CEO)inNicholas Arden Paine(Executive Officer, Director)

BoardClarence Gordon Daugherty, IV(Director)Howard Lee Morgan(Director)inGeorge Samuel Rose(Director)

Co-investorsAssembly VenturesAtinum Investment Co. Ltd.B Capital GroupB4 CapitalBaseTwoCapital Factory+22 more

Arch is a Bitcoin-native chain and execution environment (ArchVM) that lets institutions and users borrow, lend, earn yield, swap, and build financial applications that settle directly to Bitcoin without bridging, wrapping, or leaving self-custody.

Crypto & Web3Data & InfrastructureFintech

Amine ElQaraoui(Founder)in

Co-investorsMulticoin CapitalAsymmetric

Argument builds systems for verifiable computing by combining zero-knowledge cryptography, formal verification, and distributed consensus technologies.

Crypto & Web3Deep TechDeveloper ToolsEnterprise SoftwareBoston, US

John Burnham(Founder)inGabriel Barreto(Founder)inSamuel Burnham(Founder)in

Co-investorsSamsung NextVarys CapitalY CombinatorLombardstreet Ventures

Arweave is a decentralized ecosystem that offers grants and investment opportunities through various organizations including non-profits, DAOs, and venture studios to support projects and developers building on its network.

Cloud ComputingCrypto & Web3Data & InfrastructureFintechLondon, GB

Sam Williams(Founder & CEO)

Co-investors1k(x)1kxa16z cryptoAdvanced BlockchainAndreessen HorowitzArrington Capital+22 more

The Avalanche Foundation is a non-profit organization that supports innovation and growth in the Avalanche ecosystem through grants, programs, and strategic support for developers, entrepreneurs, and communities building on the Avalanche blockchain platform.

Crypto & Web3Data & InfrastructureDeveloper ToolsEnterprise SoftwareFintech

Emin Gun Sirer(Founder)in

Co-investorsa16z cryptoAegis VentuesAndreessen HorowitzAndromeda CapitalBaseTwoBig Candle Capital+25 more

Bio Protocol is a decentralized science (DeSci) platform where people can fund, develop and govern tokenized early-stage scientific research from universities, companies and researchers.

AI & Machine LearningBiotechCrypto & Web3

Co-investorsBinance LabsPfizer VenturesPolymorphic CapitalSerafundSMAPE CapitalSora Ventures+2 more

BitRobot is a decentralized network that coordinates researchers, hardware operators, and compute providers to advance embodied AI and robotics R&D.

AI & Machine LearningCrypto & Web3Robotics

Michael Cho

Co-investorsTioga Capital Partners

Bulk is a decentralized trading platform that aims to combine the decentralized custody of a DEX with the execution performance of a centralized exchange.

Crypto & Web3

Co-investors6th Man VenturesChapter OneWintermuteRobot VenturesStride Ventures

Co-investorsMaven 11V3V VenturesVarys Capital

Pump.fun is a platform that lets anyone create and trade coins, with open access to buy and sell from launch.

Crypto & Web3

Co-investors6th Man VenturesD1 VenturesLattice CapitalWintermute

ZAR is a financial app that lets people in countries with volatile local currencies send, hold, and spend US dollars.

ConsumerCrypto & Web3Fintech

Crossmint builds developer tools that let companies, AI agents, and users work with blockchain and stablecoin rails without dealing with the underlying complexity.

Crypto & Web3Developer ToolsFintechSaaSNew York, US

Rodri(Co-founder)Alfonso(Co-founder)Alfonso Gómez-Jordana Mañas(Founder)Rodri Fernández Touza(Founder)in

Co-investors6th Man VenturesAbstract VenturesCommerce VenturesGMO VenturePartnersHash3 CapitalInformed Ventures Advisors, Llc+2 more

Raiku is a lightweight Solana validator client offering Ahead-Of-Time compute reservations and Just-In-Time MEV bundle processing optimized for latency and throughput.

Crypto & Web3Data & Infrastructure

Co-investorsFigmentReciprocal Ventures

Utexo provides Lightning Network infrastructure for payment service providers to process USDT payments with configurable fees and enable BTC-to-USDT settlement and yield.

Crypto & Web3Data & InfrastructureFintech

Co-investorsMaven 11Paper Ventures

Daxo Robotics develops a highly dexterous, tendon-driven robotic hand with 120 tendens and high degrees of freedom, offered with a Python-first API, ROS wrapper, and simulation assets.

Deep TechHardwareRobotics

Co-investorsNextFab Ventures

Dyna develops general-purpose robots powered by foundation models that adapt across environments and learn new skills rapidly, with deployment across a fleet that continuously improves.

AI & Machine LearningDeep TechRobotics

Lindon Gao(Founder)Jason Ma(Founder)inYork Yang(Founder)in

Co-investorsCRV (Charles River Ventures)HCVCINCE CapitalLG Technology VenturesSamsung NextSancus Ventures+4 more

Enhanced offers clinician-prescribed peptides, prescriptions, and supplements sourced from licensed US pharmacies, with lab monitoring, delivered via a telehealth model.

ConsumerDigital HealthWellness & Fitness

Exabits provides AI compute infrastructure by refining GPU assets (such as GB200s, H100s, H200s, and RTX5090s) from leading manufacturers to support AI workloads.

AI & Machine LearningCloud ComputingData & Infrastructure

Co-investorsBloccelerate VCEdessa CapitalFOMO VenturesGenerative VenturesLBANK LabsMoonhill Capital+4 more

exo connects Macs and workstations into a single local inference cluster, automatically discovering devices, mapping network topology, and splitting AI models across device memory to run frontier models on-premises.

AI & Machine LearningDeep TechDeveloper Tools

Co-investorsArchetypeBreedPragma VenturesRobot Ventures

Flashbots is a research and development organization that mitigates negative externalities from Maximal Extractable Value (MEV) on blockchains, primarily Ethereum, through infrastructure and tools for block building, transaction protection, and MEV distribution.

Crypto & Web3Data & InfrastructureDeveloper Tools

Co-investorsBlueYard CapitalDragonflyEthereal Ventures Management Ltd.Fabric VenturesFactionFenbushi Capital+12 more

Fortytwo operates a sovereign, participant-owned AI network that uses swarm inference to combine heterogeneous AI models into a single networked intelligence.

AI & Machine LearningCloud ComputingDeep Tech

Alex Firsov(Founder)in

Co-investorsEv3 Ventures Llc

FrodoBots turns tele-operation of robots into a game, using gamers' actions as training data to develop embodied foundational AI models.

AI & Machine LearningGamingRobotics

GLIF provides DeFi and liquid staking infrastructure for the Filecoin network, including staking pools and a loyalty rewards program tied to its $GLF token.

Crypto & Web3Data & InfrastructureFintech

Jonathan Schwartz(Founder)

Co-investorsMulticoin CapitalZee Prime CapitalStruck CapitalAndreessen HorowitzFinTech CollectiveProtocol Labs

Grass operates a network that lets users share their unused internet bandwidth with verified institutions in exchange for rewards paid as points, Grass Tokens, or USDC.

ConsumerCrypto & Web3Data & Infrastructure

Co-investorsChronos VenturesCogitent VenturesCVP NoLimitLattice CapitalNo Limit Holdings (NLH)Hack VC

GTE is a decentralized exchange platform that enables trading of stocks, crypto, and commodities from a single account on a blockchain-based system, offering centralized-exchange-level speed and performance with decentralized properties.

Crypto & Web3FintechNew York City, US

Matteo Lunghi(Founder)

Co-investorsParadigmRobot VenturesMaven 11MITONMitonCWintermute

Haiku is a legal AI assistant for lawyers, legal professionals, and regulated professions, offering natural-language search across internal documents and French and European law, multi-document analysis, drafting/production (including a Word add-in), and reusable workflow "skills".

AI & Machine LearningLegalTechSaaS

Co-investorsNewfund Capital

Helius is Solana's leading infrastructure provider offering high-performance RPC nodes, transaction sending services, and data streaming tools for developers, traders, and applications.

Crypto & Web3Data & InfrastructureDeveloper ToolsToronto, CA

Nicolas Pennie(Founder)inLiam Vovk(Founder)inMert M(Founder)

BoardAnatoly Yakovenko

Co-investorsHaun VenturesFoundation CapitalFounders Fund6th Man VenturesChapter OnePropel Venture Partners+12 more

Hemi is a DeFi infrastructure layer that combines Bitcoin security with EVM programmability, letting institutions deploy native BTC into compliant yield strategies while retaining custody.

Crypto & Web3Data & InfrastructureFintech

Co-investorsImpossible FinanceTRGCWeb3com Ventures

Hyperbolic provides on-demand, reserved, and private cloud access to high-performance GPUs (such as H100, H200, and B200) through a global network of compute providers.

AI & Machine LearningCloud ComputingData & Infrastructure

Co-investorsAmbush CapitalFactionGSRLongHash VenturesSamsung NextVariant Fund+4 more

Ika is a decentralized MPC network on Solana that introduces "dWallets," a primitive splitting signing authority between users and Solana programs to control native assets on other blockchains without bridges or centralized custody.

AI & Machine LearningCrypto & Web3Data & Infrastructure

Co-investorsCollider VenturesCVP NoLimitFlowdeskLvna CapitalNo Limit Holdings (NLH)Node Capital+3 more

Inco provides a confidentiality layer that integrates with existing blockchains, using isolated hardware environments and cryptography to protect address and transaction details.

Crypto & Web3CybersecurityDeveloper Tools

Co-investorsCoinbase VenturesGSRSymbolic CapitalZero Knowledge Validator (ZKV)1kxScript Capital+1 more

Inference Labs develops cryptographic verification systems for autonomous AI agents, robots, and other autonomous systems, enabling auditable and trustworthy decision-making through zero-knowledge proofs and verifiable computing.

AI & Machine LearningCrypto & Web3Deep Tech

Co-investorsEdessa CapitalLvna Capital

Initia provides blockchain infrastructure that connects full-stack applications through integrated protocols and aligned economic incentives.

Crypto & Web3Data & Infrastructure

Co-investorsA.Capital VenturesFigmentHack VCNascentTheory Ventures

Kash operates a mobile payment system that processes transactions directly from bank accounts to merchants, bypassing credit card networks and intermediaries to reduce transaction fees.

FintechSan Francisco, US

Geoff Flarity(Founder/COO)in

Co-investorsY CombinatorCoinbase VenturesFabric VCKosmos VenturesMoonrock Capital

Kash is a social-native prediction market that turns social media posts into tradable markets, letting users predict on sports, crypto prices, and other events by reposting and tagging its bot on X.

AI & Machine LearningConsumerCrypto & Web3

Legend is a social trading platform where users copy trades from other traders, follow live alerts, and trade with up to 50x leverage.

Crypto & Web3FintechSocial

Co-investorsElectric CapitalMitonC

Mach Industries designs and manufactures defense systems including unmanned aerial systems, precision munitions, high-altitude surveillance platforms, and propulsion testing capabilities for military applications.

Defense TechHardwareHuntington Beach, US

Ethan Thornton(Executive Officer, Director)Brendan Cooney(Executive Officer)

BoardKeith Rabois(Director)inGeoff Lewis(Director)inLewis Geoff(Director)

Co-investorsAloft VCBedrockChampion Hill VenturesCoalitionDefense AngelsGreycroft+7 more

Magna is an all-in-one platform for crypto companies to launch, manage, and scale tokens, offering token operations, treasury management, stablecoin management, and distribution across a global web3 ecosystem.

Crypto & Web3Developer ToolsEnterprise SoftwareFintechSaaSNew York City, US

Bruno Faviero(Founder)inArun Kirubarajan(Founder)in

Co-investorsBehind Genius VenturesDorm RoomMarin Digital VenturesOlive Tree CapitalY CombinatorAsymmetric+2 more

MeanFi provides DeFi infrastructure and a treasury toolkit for businesses and individuals to manage crypto assets on the Solana blockchain, offering features such as multisig wallets, real-time token streaming, payroll, vesting, lending, and payment collection.

Crypto & Web3Data & InfrastructureFintech

Co-investorsOpen Opportunity FundSolar Eco FundDeFiance CapitalGerstenbrot CapitalSkyVision Capital

MegaETH is a high-performance blockchain that settles on Ethereum, offering over 100,000 transactions per second and sub-10-millisecond block times.

Crypto & Web3Data & InfrastructureFintech

Co-investorsFigmentMitonCRobot Ventures

Merge Labs is a research lab developing brain-computer interfaces that connect with neurons using molecules instead of electrodes and non-invasive modalities like ultrasound, integrated with AI.

AI & Machine LearningBiotechDeep Tech

Co-investorsAntiSciFi VC

Monad is a high-performance EVM-compatible blockchain designed for fast, low-cost transactions.

Cloud ComputingCrypto & Web3Data & Infrastructure

Keone Hon(Founder & CEO)in

Co-investorsAlphaLab CapitalAmbush CapitalArchetypeBankless VenturesBloccelerate VCBODL+23 more

Mysten Labs builds infrastructure and tools for web3, focusing on making decentralized systems secure, reliable, and ready for mass adoption.

Cloud ComputingCrypto & Web3Deep TechDeveloper ToolsPalo Alto, US

Adeniyi Abiodun(Founder)inKostas Kryptos Chalkias(Founder)Sam Blackshear(Founder)Evan Cheng(Founder)in

Co-investorsa16z cryptoAlumni VenturesAndreessen HorowitzArrington CapitalBasecamp FundChamaeleon+21 more

NEAR is an open blockchain infrastructure powering the agent economy, providing cross-chain execution, confidential settlement, and private inference capabilities.

AI & Machine LearningCloud ComputingCrypto & Web3Miami, US

Illia Polosukhin(Co-Founder)

Co-investorsA.Capital Venturesa16z cryptoAccompliceAdvanced BlockchainAmbush CapitalAmplify Partners+36 more