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AbbVie

Venture capitaloperating company · company profile

Cambridge · Seed–Late Stage · 13 people tracked

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Investment thesis

Very early discovery and preclinical therapeutics company-creation partner tightly integrated with AbbVie R&D, offering founders direct in-house expertise in oncology, immunology, neuroscience and development/commercial infrastructure.

Stage
Seed–Late Stage
Check
$300K – $3M
HQ
Cambridge, Massachusetts, US
Leads rounds
Follows
Instruments
Equity
Founded
2009
Last 12 months
1 investment
Tracked investments
17
IPOs
2
Acquisitions
1

Team · 13 people

from curated & public directories

17 people who came through AbbVie went on to found or lead other companies.

+ 5 more →

What they invest in

from 16 of 17 portfolio companies

Biotech ×16Healthtech ×5Medical Devices ×3AI & Machine Learning ×2Longevity ×2Deep Tech ×1Digital Health ×1

HQs:United States×9Italy×1

Investments · 17 tracked

founders shown can be your intro path

By year:2026 · 12025 · 12024 · 12020 · 22018 · 32017 · 311 dated

Enanta Pharmaceuticalsenanta.comin𝕏NASDAQ: ENTA

Enanta Pharmaceuticals is a biotechnology company that discovers and develops small-molecule therapeutics using chemistry-based research to treat diseases with high unmet medical need.

Biotech

Jay R. Luly(President, Director and Chief Executive Officer)Yat Sun Or(Chief Scientific Officer)Scott T. Rottinghaus(Chief Medical Officer)inMatthew P. Kowalsky(Chief Legal Officer and Corporate Secretary)Tara L. Kieffer(Chief Product Strategy Officer)inBrendan Luu(Chief Business Officer)in

Co-investorsSaints CapitalSofinnova Ventures

ExicureinNASDAQ: XCUR

Exicure is a publicly-traded holding company that previously developed nucleic acid therapies and has since divested its historical biotechnology assets; it is now pursuing growth through acquisitions and partnerships, including a recent investment in GPCR Therapeutics USA, which is developing small molecule therapies for blood cancers and multiple myeloma.

BiotechSkokie, US

Chad A. Mirkin(Director)C. Shad Thaxton(Director)David A. Giljohann(Chief Executive Officer)inDavid S. Snyder(Chief Financial Officer)inPercy Van Crocker, Jr.(Vice President, Commercial Development)

BoardJay Venkatesan(Director)

Co-investorsInnovation EndeavorsPurple Arch VenturesRockPort Capital Partners

Lighthorsetxlighthorsetx.com✓ verified

Light Horse Therapeutics is a drug discovery company applying scientific expertise and innovation to advance healthcare through collaborative development.

AI & Machine LearningBiotechMedical Devices

Co-investorsTaiho Ventures, LLCMubadala CapitalVersant Ventures

Aquinnah Pharmaceuticalsaquinnahpharma.comApr 2017 · $10M

Aquinnah Pharmaceuticals develops oral small-molecule therapeutics targeting pathologic biomolecular condensates, such as stress granules formed by RNA-binding proteins, to slow neurodegenerative diseases including ALS and Alzheimer's disease.

BiotechHealthtechLongevity

Benjamin Wolozin(CSO & Co-founder)

Co-investorsPfizer Venture Investments

Carawaycarawaytx.comin𝕏Series A · Nov 2018 · $23Macquired by Merck

Caraway Therapeutics was a preclinical biopharmaceutical company developing small-molecule therapies modulating lysosomal function to treat neurodegenerative and rare diseases.

BiotechHealthtech

Co-investorsDementia Discovery FundEisai Innovation, Inc.McCarthy CapitalMRL Ventures FundSV Health InvestorsBridge Investments+9 more

Carisma Therapeuticscarismatx.comSeed · Jun 2017

CAR-Macrophage cellular therapeutics with initial oncology focus (NASDAQ: CARM).

BiotechPhiladelphia, US

Steven Kelly(Executive Officer, Director)in

BoardMargarita Chavez(Director)inEran Nadav(Director)Althea Stillman(Director)Jacob Gunterberg(Director)Regina Hodits(Director)in

Co-investorsAgent CapitalAju IB Invesment CorporationAnzu PartnersGrazia Equity GmbHHealthCapMRL Ventures Fund+3 more

Entheraentherapharmaceuticals.cominSeries A · Jul 2020 · $33M

Enthera Srl is a privately held pharmaceutical company founded in 2016 and based in Milan, Italy.

BiotechHealthtechMilan, IT

Co-investorsSofinnova PartnersIndaco Venture PartnersRoche Venture FundJDRF T1D Fund

Leal Therapeuticslealtx.comSeries A · Oct 2024 · $45M

Leal Therapeutics is a company focused on CNS (central nervous system) disorders, drawing on academic and drug-development experience in neurology and neurodegenerative disease.

BiotechHealthtechMedical DevicesWorcester, US

Asa Abeliovich(CEO & Founder, Director)

Co-investorsOrbiMedSV Health InvestorsNewpath Partners

Nitrase Therapeuticsnitrasetx.cominSeries A · Apr 2020 · $38M

Nitrase Therapeutics is a clinical-stage biopharmaceutical company using its NITROME platform to develop therapeutics based on nitrases, a class of enzymes it discovered that drive protein nitration.

BiotechHealthtechLongevity

Irene Griswold-Prenner(Founder & Chief Executive Officer)in

Co-investorsDementia Discovery FundMission BiocapitalSofinnova PartnersSV Health InvestorsMission Bay Capital

Ribometrixribometrix.comSeed · Oct 2017 · $8M

BiotechGreenville, US

Kevin Weeks(Executive Officer, Director)Katherine Warner(Executive Officer)Joshua Resnick(Director)Michael Solomon(Director)John Gustofson(Director)

BoardMike Dial(Director)in

Co-investorsHatteras Venture PartnersIllumina VenturesM VenturesMC Healthcare VenturesPappas CapitalSV Health Investors+2 more

Ribon Therapeuticsribontx.comin

BiotechLexington, US

Victoria M. Richon(Executive Officer, Director)in

BoardCameron Wheeler(Director)Jonathan Root(Director)Laurence Lasky(Director)

Co-investorsAvego BioScience CapitalOUP (Osage University Partners)Peregrine VenturesDeerfield Management CompanyJJDCNovartis Venture Fund+4 more

Stylus Medicinestylusmedicine.cominSeries A · May 2025 · $85M

Stylus Medicine develops in vivo genetic medicines using engineered recombinases, with initial focus on creating CAR-T therapies delivered via lipid nanoparticles for oncology, autoimmune, and genetic diseases.

BiotechDigital HealthMedical Devices

Michael C. Bassik, Ph.D.(Scientific Founder)Emile Nuwaysir, Ph.D.(Chairman & Chief Executive Officer)inJason Fontenot, Ph.D.(Chief Scientific Officer)

Co-investorsBrainstorm VenturesCALIFORNIA INNOVATIONKhosla VenturesNeva Sgr.RA CapitalTachyon Ventures

Ten63 Therapeuticsten63tx.cominFeb 2026

Ten63 develops drug-discovery technology that combines generative chemistry with quantum-accurate molecular simulation, including BEYOND (a large quantum chemistry model) and Sentinel (a virtual CSO for target selection), to design therapeutics against previously undruggable targets.

AI & Machine LearningBiotechDeep TechDurham, US

Mark A. Hallen(Executive Officer, Director)inMarcel Frenkel(Executive Officer, Director)Damien Petty(Director)inJia Wei Xu(Director)

Co-investorsCape Fear BioCapitalDFJ DragonFundDraper AssociatesDuke Capital PartnersHatteras Venture PartnersAlexandria+4 more

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

Lodo TherapeuticsMagnolia NeurosciencesParagen BioPetra Pharma

Exits · 3

2 IPOs · 1 acquisitions

Enanta PharmaceuticalsNASDAQ: ENTAExicureNASDAQ: XCURCarawayacq. by Merck

Portfolio news

latest coverage across their companies

IPO stake values · per SEC filings · 2

Value of this firm's stake in each portfolio company at its IPO price, from the prospectus principal-stockholder table.

CompanyOwnedIPO priceAt IPOStake value
Enanta Pharmaceuticals6.4%$14.00Mar 2013$15M
Exicure—$3.00Jan 2018$5.8M

Source: SEC S-1 / 424B prospectus filings. Stake value = shares beneficially owned × the initial public offering price, as disclosed — a market value at IPO, not a return multiple (the firm's original cost is not disclosed).

Frequently asked questions

How many investments has AbbVie made?
AbbVie has 17 tracked investments, 3 of which have exited, including 3 dated in the last 24 months.
What stage does AbbVie invest at?
AbbVie invests at the Seed, Series A, Late Stage stages.
What is AbbVie's typical check size?
AbbVie typically writes checks of $300K – $3M.
What sectors does AbbVie focus on?
AbbVie focuses on Biotech.
Where is AbbVie located?
AbbVie is headquartered in Cambridge, US.
Does AbbVie lead rounds?
AbbVie typically participates in rounds rather than leading them.

Co-investors · 6

Sofinnova Partners

Sofinnova Partners is a life sciences venture capital firm investing across the value chain from seed to later stage, with a focus on healthcare and sustainability. It backs companies in biopharma, medtech, digital medicine, agriculture and industrial processes.

$540K – $27M
Hatteras Venture Partners

Hatteras Venture Partners is a venture capital firm focused on early-stage life sciences and healthcare companies, backing therapeutics, diagnostics, and businesses aiming to transform healthcare delivery and innovation.

$500K – $4M
M Ventures

M Ventures is the corporate venture arm of Merck KGaA based in Darmstadt, Germany, operating from offices in Amsterdam, the US, and Israel. The firm invests globally across early-stage companies and spin-offs in areas aligned with Merck's core business, taking active roles in portfolio company development.

$10.8M
RA Capital

RA Capital Management is a healthcare and planetary health investment firm that founds, funds, and scales companies using scientific diligence, multi-stage capital, and hands-on operational support.

Both backed · 1
Morpheus Ventures

Morpheus Ventures is a venture capital fund that backs early-stage companies and supports founders through the challenges of scaling toward hyper-growth.

Both backed · 1
$1M – $10M
Agent Capital

Agent Capital is a healthcare venture capital firm that makes direct equity investments in novel, differentiated therapeutics and treatments addressing unmet patient needs, from preclinical through commercial stages.

Both backed · 1

Firms observed investing alongside AbbVie, from public investor directories. Shared companies are the overlap with AbbVie's recorded portfolio.

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