Synapticure

Synapticure is a specialty telehealth clinic focused on neurodegenerative disease. It pairs each patient and caregiver with a dedicated care team and a subspecialty neurologist seen over video, then produces a personalized care plan with 24/7 support and coordination with the patient's existing local physicians. Clinical scope spans three categories: cognitive conditions (Alzheimer's disease, other dementias, mild cognitive impairment, Lewy body dementia, frontotemporal dementia), neuromuscular conditions (ALS, primary lateral sclerosis, progressive muscular atrophy, progressive bulbar palsy and other motor neuron diseases), and movement disorders (Parkinson's disease, Huntington's disease, essential tremor, ataxias, atypical parkinsonism, progressive supranuclear palsy, multiple system atrophy, corticobasal degeneration). It also offers behavioral and mental health services for patients and caregivers, including individual and group therapy, psychiatric support and counseling [0][2][3].

The care team includes care coordinators (LCSWs and RNs), specialized neurologists, geriatricians, psychiatrists, psychologists, speech-language therapists/pathologists, nurse practitioners, genetic counselors and insurance navigators. Services extend to care coordination, genetic testing and counseling, speech and language therapy, insurance guidance, and access to emerging treatments and clinical trials, including in-home research capacity operated as a single standardized clinical operation across 50 states [3][4][5][6].

The company states its medical practice is licensed in all 50 states and Washington, D.C., and it has been selected as a provider under the CMS GUIDE (Guiding an Improved Dementia Experience) model in all 50 states [3][5][6].

Founding story

Co-founders Brian Wallach (patient) and Sandra Abrevaya (caregiver, CEO) started the company after Brian's ALS diagnosis, drawing on backgrounds in healthcare and policy and on their advocacy work documented in the film No Ordinary Campaign. The Series A release lists founders as Sandra Abrevaya, Brian Wallach, Peter Wallach, Jason Langheier and Jonathan Hirsch. The name combines "synapse," the site of communication in the brain, with "cure." One third-party profile instead lists 2019 founders as Peter Wallach, Martina de Majo and Brian Wallach [4][5][6][7].

Business model

Synapticure operates a national virtual medical group rather than a subscription or concierge service; it bills patients' health plans after appointments in the manner of an in-person physician office, and partners with accountable care organizations, health systems and health plans, as well as participating in the CMS GUIDE dementia care model [3][5][6].

Fee-for-service reimbursement billed to health insurers, with no subscription or membership fee; the company states most in-network visits cost patients $0-40 out of pocket. Additional revenue relationships come from partnerships with ACOs, health systems, payers and the CMS GUIDE model [3][5][6].

Traction

Several thousand patients served across the United States as of November 2024, licensed in all 50 states and Washington, D.C., selection as a CMS GUIDE dementia model provider in all 50 states, and $25 million Series A financing from a syndicate of strategic and venture investors [3][5][6].

Latest developments

In November 2024 the company closed a $25 million Series A led by B Capital, with proceeds earmarked for expanding provider and payer partnerships, investing in its technology platform and AI-enabled analytics, accelerating clinical research and trial access, and scaling its national medical group. Its website prominently promotes its role as a CMS GUIDE partner for dementia support [0][5][6].