Fundraising FoxCity Hill Ventures
Venture capitalSan Diego · Seed–Series A · 1 people tracked
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Investment thesis
City Hill Ventures began as a healthcare-focused venture firm in San Diego and has expanded into cleantech and media & entertainment. It describes its team as 'venturepreneurs' who Found, Fund and Lead companies — sometimes founding new ventures around promising technologies, investing in companies with strong management, and taking active operational or advisory roles. The firm concentrates its capital and expertise on a small number of portfolio companies at a time, an approach it credits with generating outsized returns. It also makes passive investments alongside strong teams or syndicates, co-investing with leading healthcare investors. It operates two funds: a closed healthcare-only Fund I and an evergreen Fund II targeting industries capable of catalyzing global change.
Source: firm website, verified Aug 3, 2026.
Team · 1 people
from public directoriesWhat they invest in
from 4 of 4 portfolio companiesBiotech ×4Medical Devices ×2AI & Machine Learning ×1Deep Tech ×1Digital Health ×1
HQs:United States×4
Investments · 4 tracked
founders shown can be your intro pathBy year:2021 · 12020 · 12019 · 24 dated
Boundless Bio develops precision oncology medicines targeting ecDNA-amplified cancers, specifically creating a new category of ecDNA-directed therapies for patients with oncogenic alterations.
BiotechMedical DevicesLa Jolla, US
Zachary D. Hornby(Executive Officer, Director)inRobert Doebele(Chief Medical Officer)inChristian Hassig(Chief Scientific Officer)Jessica Oien(Chief Legal Officer and Corporate Secretary)in
BoardBenjamin Cravatt, Ph.D.(Director)Kristina Burow(Director)in
Co-investorsARCH Venture PartnersNextech InvestRA CapitalWellington ManagementAlexandriaNEXTECH ONCOLOGY SCSP+4 more
Erasca is a clinical-stage oncology company developing therapies targeting RAS- and MAPK pathway-driven cancers using a modality-agnostic approach including small molecules, large molecules, and protein degraders.
BiotechDeep TechDigital HealthMedical DevicesSan Diego, US
Jonathan E. Lim, M.D.(Chairman, CEO and Co-founder)Gary Yeung, CFA(Chief Business Officer)in
BoardAlexander W. Casdin(Director)Pratik S. Multani, M.D.(Director)Valerie Harding-Start(Director)James A. Bristol, Ph.D.(Director)
Co-investorsAndreessen HorowitzARCH Venture PartnersColt VenturesEvolution VC PartnersFrazier Life SciencesLifeSci Venture Partners+1 more
Maze Therapeutics develops precision medicines for common diseases with high unmet need, using its Compass platform based on human genetics and variant functionalization.
AI & Machine LearningBiotechSouth San Francisco, US
Charles Homcy(Director)Jason Coloma(Chief Executive Officer)in
Co-investorsAndreessen HorowitzARCH Venture PartnersForesite CapitalFrazier Life SciencesGV (Google Ventures)Hercules Capital, Inc.+9 more
BiotechPhoenix, US
Douglas Grant McFadden, Ph.D.(Director)Steven J. Potts, Ph.D.(President and Chief Executive Officer)Ting Xiao(Director)Jason Rushton(Director)Kanad Das, Ph.D.(Director)Michael G. Wood(Executive Officer)
Co-investorsXeraya CapitalB Capital GroupBoehringer Ingelheim Venture FundDelos CapitalKorea Investment PartnersLumira Ventures+1 more
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Exits · 3
3 IPOsBoundless BioNASDAQ: BOLDErascaNASDAQ: ERASMaze TherapeuticsNASDAQ: MAZE
Frequently asked questions
- What stage does City Hill Ventures invest at?
- City Hill Ventures invests at the Seed, Series A stages.
- What is City Hill Ventures's typical check size?
- City Hill Ventures typically writes checks of $100K – $20M.
- What sectors does City Hill Ventures focus on?
- City Hill Ventures focuses on Biotech, Cleantech, Healthtech, Media & Entertainment, Medical Devices.
- Where is City Hill Ventures located?
- City Hill Ventures is headquartered in San Diego, US.
- Does City Hill Ventures lead rounds?
- Yes, City Hill Ventures leads investment rounds.
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