City Hill Ventures
Venture capitalSan Diego · Seed–Series A · 1 people tracked
Investment thesis
City Hill Ventures began as a healthcare-focused venture firm in San Diego and has expanded into cleantech and media & entertainment. It describes its team as 'venturepreneurs' who Found, Fund and Lead companies — sometimes founding new ventures around promising technologies, investing in companies with strong management, and taking active operational or advisory roles. The firm concentrates its capital and expertise on a small number of portfolio companies at a time, an approach it credits with generating outsized returns. It also makes passive investments alongside strong teams or syndicates, co-investing with leading healthcare investors. It operates two funds: a closed healthcare-only Fund I and an evergreen Fund II targeting industries capable of catalyzing global change.
Source: firm website, verified Aug 3, 2026.
Team · 1 people
from public directoriesWhat they invest in
from 1 of 1 portfolio companiesBiotech ×1Deep Tech ×1Digital Health ×1Medical Devices ×1
HQs:United States×1
Investments · 1 tracked
founders shown can be your intro path
Erasca is a clinical-stage oncology company developing therapies targeting RAS- and MAPK pathway-driven cancers using a modality-agnostic approach including small molecules, large molecules, and protein degraders.
BiotechDeep TechDigital HealthMedical DevicesSan Diego, US
Jonathan E. Lim, M.D.(Chairman, CEO and Co-founder)Gary Yeung, CFA(Chief Business Officer)
BoardAlexander W. Casdin(Director)Pratik S. Multani, M.D.(Director)Valerie Harding-Start(Director)James A. Bristol, Ph.D.(Director)
Co-investorsAndreessen HorowitzARCH Venture PartnersEvolution VC PartnersFrazier Life SciencesColt VenturesLifeSci Venture Partners
Exits · 1
IPOs and acquisitions across the tracked portfolioErascaNASDAQ: ERAS
Portfolio news
latest coverage across their companies
Frequently asked questions
- What stage does City Hill Ventures invest at?
- City Hill Ventures invests at the Seed, Series A stages.
- What is City Hill Ventures's typical check size?
- City Hill Ventures typically writes checks of $100K – $20M.
- What sectors does City Hill Ventures focus on?
- City Hill Ventures focuses on Biotech, Cleantech, Healthtech, Media & Entertainment, Medical Devices.
- Where is City Hill Ventures located?
- City Hill Ventures is headquartered in San Diego, US.
- Does City Hill Ventures lead rounds?
- Yes, City Hill Ventures leads investment rounds.
Similar investors
Amadeus Capital Partners is a technology investment firm that backs founders building complex, science-led and deep tech businesses, supporting them over the long term as they scale internationally.
EDBI is the investment platform of Singapore's Economic Development Board and Enterprise Singapore, focusing on high-growth technology companies expanding into Singapore and Asia.
Khosla Ventures is a venture capital firm that invests in early-stage companies focused on technology, mobile, and clean energy sectors, including biotechnology applications. The firm provides capital and strategic support to entrepreneurs developing breakthrough technologies across multiple markets.
Mohr Davidow Ventures is a venture capital firm that backs entrepreneurs pursuing large market opportunities and capable of attracting top-tier talent.
GO Capital is a French investment firm founded in 2003 that backs high-growth companies in digital, health, and industry-of-the-future sectors, with a focus on sustainable innovation across regional territories.