Fundraising Fox

Alta Partners

Venture capital

Jackson · Seed–Growth · 9 people tracked

Also known as ALTA PARTNERS INVESTMENT MANAGER, L.P. · ALTA PARTNERS MANAGEMENT COMPANY, L.P. · Alta Partners NextGen

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Investment thesis

Alta Partners believes the healthcare sector has reached an inflection point where technology and innovation enable greater integration among physicians, payers, and patients to deliver better outcomes. The firm holds that healthcare should ultimately serve patients, and it is dedicated to supporting entrepreneurs in building high-impact companies. Its portfolio and outcomes center on life sciences and biotechnology, including cell and gene therapies, precision medicines, and clinical-stage biopharmaceutical companies.

Invests inBiotechDigital HealthHealthtechLongevityMedical DevicesGlobalJacksonSan FranciscoUnited States

Source: firm website, verified Aug 3, 2026.

Stage
Seed–Growth
Check
$1M – $12M
HQ
Jackson, Wyoming, US
Instruments
Equity
Founded
1996
AUM
$2.8B
VC funds
1
Tracked investments
66

Team · 9 people

from the firm's website & public directories
Marino Polestra

Co-founder of Alta Partners in 1996 and a former senior partner of Burr, Egan, Deleage & Co.

What they invest in

from 22 of 66 portfolio companies

Biotech ×13Healthtech ×11Medical Devices ×5Deep Tech ×2Digital Health ×2SaaS ×2AI & Machine Learning ×1B2B Marketplaces ×1

HQs:United States×24

Investments · 66 tracked

founders shown can be your intro path
Krystal BiotechNASDAQ: KRYSSEC filingmedium confidence

BiotechPittsburgh, US

Doug Norby(Director)Dan Janney(Director)Dino Rossi(Director)Suma M. Krishnan(Director)Krish S. Krishnan(Executive Officer, Director)

Board seatDan Janney· per SEC Form D · $11.3M raise · filed Aug 2017

BioventusNASDAQ: BVS

Received FDA 510(k) clearance for its StimRouter pain management device and SonaStar Elite.

TransMedicsNASDAQ: TMDX

HealthtechAndover, US

Edwin M. Kania, Jr.(Director)Waleed H. Hassanein(Executive Officer, Director)James R. Tobin(Director)Kenneth Bate(Director)David Abrams(Director)Joseph S. Lacob(Director)

TYRA Biosciencestyra.bioinNASDAQ: TYRA

BiotechCarlsbad, US

Robert More(Director)Hiroomi Tada, M.D., Ph.D.(Executive Officer)Isan Chen, M.D.(Director)Daniel Bensen(Executive Officer)Nina Kjellson(Director)Alan Fuhrman(Executive Officer)

Vir BiotechnologyNASDAQ: VIR

San Francisco, US

Allakos Incallakos.com

BiotechSan Carlos, US

Nenad Tomasevic(Executive Officer)Farah Champsi(Director)Alejandro Dorenbaum(Executive Officer)Peter Moldt(Director)Christopher Bebbington(Executive Officer, Director)

BoardJohn McKearn(Director)

Board seatDan JanneyFarah Champsi· per SEC Form D

Calthorpe AnalyticsSEC filingmedium confidence

Berkeley, US

Peter Calthorpe(Executive Officer, Director)

Board seatGarrett Gruener· per SEC Form D · $2M raise · filed Jul 2019

Carbylan TherapeuticsSEC filingmedium confidence

HealthtechPalo Alto, US

DAVID CLAPPER(Director)ALBERT CHA(Director)EDWARD W. UNKART(Director)GUY P. NOHRA(Director)MARCEE M. MARONEY(Executive Officer)DAVID GRAVETT(Executive Officer)

Board seatGuy Nohra· per SEC Form D · $4M raise · filed Mar 2015

Kelonia Therapeutics, Inc.SEC filingmedium confidence

Cambridge, US

Board seatBob More· per SEC Form D · $50.3M raise · filed Apr 2022

Progentos Therapeuticsprogentos.com

Progentos develops small-molecule therapeutics to stimulate myelin regeneration in multiple sclerosis patients by activating oligodendrocyte progenitor cells.

BiotechDeep TechMedical DevicesWatertown, US

Aleks Radovic-Moreno(Director)Dmitrij Hristodorov(Director)Dan Janney(Director)Christopher Loose(Executive Officer, Director)Cassidy Blundell(Director)Sanjay Magavi(Executive Officer)

Board seatDan Janney· per SEC Form D

Prolactaprolacta.comin𝕏

Prolacta Bioscience manufactures 100% human milk-based nutritional products and fortifiers for premature and critically ill infants in hospital neonatal intensive care units.

BiotechHealthtechMedical DevicesCity Of Industry, US

Scott Elster(Executive Officer, Director)Frank Foster(Director)Martin Sutter(Director)John Bacich, Jr.(Director)Ernie Strapazon(Director)Ned Brown(Director)

Board seatDan Janney· per SEC Form D

Spiral TherapeuticsSEC filingmedium confidence

BiotechHealthtechSouth San Francisco, US

WARREN THALER(Director)Eugene de Juan(Executive Officer, Director)ANTHONY ADAMIS(Director)FREDERIC GUERARD(Director)JEAN-FREDERIC PAULSEN(Director)Guy Jean Savoir Garcia(Director)

Board seatGuy Nohra· per SEC Form D · $10.9M raise · filed Feb 2023

Usgi MedicalSEC filingmedium confidence

HealthtechSan Clemente, US

Mike Chuisano(Director)Tracy Maahs(Executive Officer)Scott Moonly(Executive Officer, Director)George Abi-Chahine(Director)John Cox(Executive Officer)Guy Nohra(Director)

Board seatGuy Nohra· per SEC Form D · $4M raise · filed Jun 2019

VertiFlexSEC filingmedium confidence

HealthtechSan Clemente, US

Kathy Tune(Director)Peter Justin Klein(Director)Sigrid Van Bladel(Director)Jeff Swiecki(Executive Officer)Earl R. Fender(Executive Officer, Director)Guy P. Nohra(Director)

Board seatGuy Nohra· per SEC Form D · $5M raise · filed Jul 2015

Aeriepharmaaeriepharma.comin

Aerie Pharmaceuticals develops ophthalmic pharmaceutical products including Rocklatan and Rhopressa for glaucoma and ocular hypertension, and AR-15512 for dry eye disease.

BiotechHealthtechMedical Devices

Allakos

Portfolio company that completed a successful 2018 biotech IPO, resulting in a 9x return for RiverVest.

PartnerDan Janney· led

Ally Therapeutics

BiotechCambridge, US

Tina Liu(Executive Officer, Director)David Cordo(Executive Officer)Erica Whittaker(Director)Steve Gillis(Director)

BoardBob More(Director)

Amplitude Therapeutics, Inc.
Amplitude Txamplitude-tx.com
Ark PESarkpes.com

Ark provides a customizable digital platform for venture capital and private equity firms to manage investor communications, performance reporting, and document sharing with their limited partners.

Enterprise SoftwareFintechSaaS

Bebiopharmabebiopharma.com
Bettervetbettervet.com

Boston, US

Dan Adams(Executive Officer, Director)

BoardPete Hudson(Director)Bruce Herzfelder(Director)Mark Prather(Director)

Cellective Therapeuticsacquired by MedImmune

Therapeutics company acquired by MedImmune.

Chimerix

Received FDA approval for TEMBEXA (brincidofovir) to treat smallpox.

CoTherix

Received FDA approval for Tracleer to treat pulmonary arterial hypertension.

PartnerDan Janney· led

Curasencurasen.com
CuraSen Therapeutics, Inc.

BiotechSan Carlos, US

Anthony P. Ford(Executive Officer, Director)Benjamin Potter(Executive Officer)Henry Skinner(Director)Liam Ratcliffe(Director)

BoardRon Hunt(Director)Loretta Tse, Ph.D.(Director)

Cutera

Received FDA approvals for the enlighten and Secret RF microneedling systems for skin conditions.

DEM Bio
DEM BioPharmadembiopharma.com
Dispatch Healthdispatchhealth.comin

DispatchHealth delivers in-home medical care and house call services, offering patients an alternative to emergency rooms and urgent care facilities for acute medical conditions.

Digital HealthHealthtech

Dr. Mark Prather(Founder)Kevin Riddleberger(Founder)Dominic Bagnoli(Director)Pete Hudson(Director)

Edgewood Oncology, Inc.
eGenesisegenesisbio.comin

eGenesis uses gene editing and genome engineering to develop porcine donor animals for cross-species organ transplantation, addressing organ failure treatment and transplant supply constraints.

BiotechDeep TechMedical Devices

Mike Curtis, Ph.D.(President & Chief Executive Officer)

eGenesisegenesis.com

BiotechBrookline, US

Luhan Yang(President, Secretary and Treasurer)George M. Church(Director)Geoff MacKay(Chief Executive Officer)

Esperion Therapeuticsesperion.com

PartnerDan Janney· led

Everside Health
Flamel Technologies

Received FDA approvals for Vazculep and Akovaz to treat anesthesia-related hypotension.

FoldRx Pharmaceuticals

Received FDA approval for Vyndamax and Vyndaqel to treat ATTR-CM cardiomyopathy.

Free Market Healthfreemarkethealth.comin𝕏

Free Market Health operates a care-driven marketplace platform for the specialty pharmacy ecosystem.

B2B MarketplacesHealthtechSaaSPittsburgh, US

Harbor Healthharborhealth.comin𝕏

Harbor Health is a healthcare provider and insurance company operating clinics across Texas that offers primary care, specialty care, and health coaching alongside integrated insurance coverage.

HealthtechInsurTechAustin, US

Pete Hudson(Director)Anthony Miller(Director)Sterling Claiborne Johnston(Chief Medical Officer)Jeffrey Fisher(Chief Financial Officer)Sebastian Caliri(Director)Brian Beutner(Corporate Secretary)

ILEX Oncology

Oncology company that received FDA approval for Campath to treat B-cell chronic lymphocytic leukemia.

PartnerDan Janney· led

ImmuneID
Immuneidrximmuneidrx.com
InterMune Pharmaceuticalsacquired by Roche

Pharma company acquired by Roche; received FDA approval for Esbriet to treat idiopathic pulmonary fibrosis.

Kelonia
Kelonia Therapeutics

Developing in vivo CAR-T cell therapies for cancer treatment

Keloniatxkeloniatx.com
Kite Pharmakitepharma.com
Kosan Biosciencesacquired by Bristol Myers Squibb

Biosciences company acquired by Bristol-Myers Squibb.

Lassen Therapeuticslassentherapeutics.comin
MBrace
Mbracetrxmbracetrx.comin
Novome Biotechnologies, Inc.

Daly City, US

Elizabeth Stanley(Director)Weston Whitaker(Executive Officer, Director, Promoter)Samuel Smits(Director)William DeLoache(Director)

Novomebionovomebio.com
Paladinahealthpaladinahealth.comin
PatientsLikeMepatientslikeme.comin𝕏

HealthtechCambridge, US

Philippe Amouyal(Director)Jonathan White(Director)Justin Barstein(Director)Martin Coulter(Executive Officer, Director)Jay M. Tenenbaum(Director)James Heywood(Director)

Progentos
Qihan Biotechqihanbio.com
Swedish Orphan Biovitrum (Sobi)

Received FDA approval for Elocta to treat Hemophilia A.

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

Fund performance · per public LP disclosures · 7

as of Sep 2024
FundVintageCommittedNet IRRTVPIDPI
Alta Partners VIIILPs: Employees' Retirement System of Rhode Island, Hawaii Employees' Retirement System200616.3%2.47x2.47x
Alta BioPharma Partners IIILPs: Employees' Retirement System of Rhode Island20035.8%1.50x1.42x
Alta BioPharma Partners II, L.P.LPs: California Public Employees' Retirement System20003.2%1.18x0.96x
Alta Subordinated Debt Partners IIILPs: The Regents of the University of California199328.8%3.40x3.40x
Alta Subordinated Debt Partners IILPs: The Regents of the University of California198812.1%2.12x2.12x
Alta Subordinated Debt PartnersLPs: The Regents of the University of California19868.6%1.88x1.88x
Alta Co PartnersLPs: The Regents of the University of California198013.6%2.22x2.22x

Source: public limited-partner disclosures (CalPERS, CalSTRS). Net IRR / TVPI / DPI as reported by the limited partner; a fund's early-year IRR is an interim estimate (J-curve).

Frequently asked questions

What stage does Alta Partners invest at?
Alta Partners invests at the Seed, Series A, Series B, Series C, Growth stages.
What is Alta Partners's typical check size?
Alta Partners typically writes checks of $1M – $12M.
What sectors does Alta Partners focus on?
Alta Partners focuses on Biotech, Digital Health, Healthtech, Longevity, Medical Devices.
Where is Alta Partners located?
Alta Partners is headquartered in Jackson, US.

Media · Podcasts & interviews

featuring the team

Pete Hudson, Alta Partners & Transcarent Investor, Part 1

The Health Care Blog's Channel · Pete Hudson

Images

Alta Partners photo

Co-investors · 17

Longwood Fund

Longwood Fund is a Boston-based venture firm focused on discovering and building science-based companies, with a team spanning doctors, scientists, entrepreneurs, and investors.

Both backed · 5
Progentos TherapeuticsBE BiopharmaBebiopharmaDEM BioPharmaLassen Therapeutics
General Catalyst

General Catalyst is a venture capital and investment firm that backs founders across industries, with a strong focus on AI-driven transformation, fintech, healthcare, and other sectors.

$30M
Canaan Partners

Canaan is an early-stage venture capital firm backing founders with transformative ideas across technology and healthcare.

Both backed · 2
TYRA BiosciencesEsperion Therapeutics
$500K – $20M
Aisling Capital

Aisling Capital is an investment firm focused on companies developing and commercializing innovative healthcare products, services, and technologies.

Both backed · 2
ProlactaEsperion Therapeutics
Questa Capital

Questa Capital is a venture capital firm that partners with teams building next-generation healthcare companies focused on improving patient outcomes and reducing costs.

$15M – $40M
RiverVest Venture Partners

RiverVest Venture Partners is a life sciences venture capital firm that invests in biotechnology and medical companies, working with entrepreneurs to advance therapeutic and medical innovations.

Both backed · 2
Allakos IncAllakos
$500K – $3M
Astellas Venture Management LLC

Astellas Venture Management (AVM) is the wholly-owned corporate venture arm of Astellas, providing equity investments to private, early-stage biotechnology companies developing therapeutic programs and platform technologies for drug discovery.

Both backed · 1
DEM BioPharma
$200K – $5M
Insight Partners

Insight Partners is a venture and growth-stage software investor featuring a large portfolio of technology companies across multiple sectors and regions.

$120M – $350M
Unknown Ventures

Unknown is an investment firm focused on emerging market opportunities in live entertainment, biosciences, technology startups, and real estate, with a portfolio spanning music festivals, artist platforms, creator financial services, and event infrastructure.

DCVC (Data Collective)

DCVC (Data Collective) is a venture capital firm that backs founders building companies which apply technology to major challenges across areas such as energy, biotech, agriculture, and machine learning.

$5M – $25M
Polaris Partners

Polaris Partners is a venture capital firm that partners with biotech and healthcare entrepreneurs to build transformational companies.

$500K – $5M
S32

S32 is a high-conviction venture firm that concentrates on a small set of core relationships, committing deeply and supporting founders over the long term.

5 more co-investors

Forbion5AM VenturesDomain AssociatesAsset Management VenturesFrazier Healthcare Partners

Firms observed investing alongside Alta Partners, from public investor directories. Shared companies are the overlap with Alta Partners's recorded portfolio.

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