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Alta Partners

Venture capitaloperating company · company profile

Jackson · Seed–Series A · 10 people tracked

Also known as ALTA PARTNERS INVESTMENT MANAGER, L.P. · ALTA PARTNERS MANAGEMENT COMPANY, L.P.

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Investment thesis

Alta Partners believes the healthcare sector has reached an inflection point where technology and innovation enable greater integration among physicians, payers, and patients to deliver better outcomes. The firm holds that healthcare should ultimately serve patients, and it is dedicated to supporting entrepreneurs in building high-impact companies. Its portfolio and outcomes center on life sciences and biotechnology, including cell and gene therapies, precision medicines, and clinical-stage biopharmaceutical companies.

Source: firm website, verified Sep 29, 2026.

Stage
Seed–Series A
Check
$1M – $12M
HQ
Jackson, Wyoming, US
Instruments
Equity
Founded
1996
Last 12 months
1 investment
AUM
$2.8B
VC funds
1
Tracked investments
74
Unicorns
2
IPOs
3
Acquisitions
7

Team · 10 people

from the firm's website & curated & public directories
Marino Polestra

Co-founder of Alta Partners in 1996 and a former senior partner of Burr, Egan, Deleage & Co.

What they invest in

from 46 of 74 portfolio companies

Healthtech ×31Biotech ×26Medical Devices ×13Digital Health ×10AI & Machine Learning ×5Enterprise Software ×4Fintech ×4SaaS ×4

HQs:United States×41China×1

Who they back

founder profiles across 22 portfolio companies
55%
solo founders
12 of 22 mapped founding teams
40%
repeat founders
of 10 founders with career history
~4 yrs
old at investment
median across 13 dated deals

Founding team size:solo founder×122 founders×63 founders×4

Where their founders worked beforefrom 10 founders with career history

New York Genome Center ×2

Investments · 74 tracked

founders shown can be your intro path

By year:2025 · 52024 · 42023 · 12022 · 22021 · 22019 · 32018 · 22017 · 22016 · 32015 · 32014 · 32012 · 134 dated

TransMedicsNASDAQ: TMDX

TransMedics develops and sells the Organ Care System (OCS), a portable warm perfusion platform for preserving and assessing donor hearts, lungs, and livers outside the body prior to transplantation, along with the National OCS Program, an end-to-end organ procurement and logistics service for transplant centers that includes aircraft and ground transportation.

HealthtechAndover, US

Waleed H. Hassanein(Executive Officer, Director)inStephen Gordon(Executive Officer)

BoardEdwin M. Kania, Jr.(Director)David Abrams(Director)Joseph S. Lacob(Director)Travis Rhodes(Director)

Co-investorsFlagship Pioneering

TYRA Biosciencestyra.bioinNASDAQ: TYRAFeb 2024

Tyra is developing oral dabogratinib, a small-molecule therapy being evaluated in clinical studies for skeletal dysplasia and urologic cancers.

BiotechHealthtechCarlsbad, US

Todd Harris, Ph.D.(Executive Officer, Director)Hiroomi Tada, M.D., Ph.D.(Executive Officer)Daniel Bensen(Executive Officer)inAlan Fuhrman(Executive Officer)inTodd Harris(President, Chief Executive Officer and Director)inBhavesh Ashar(Chief Operating Officer)in

Co-investorsBioBritNextech InvestCanaan PartnersRA Capital

Virvir.bioin𝕏NASDAQ: VIR

Vir Biotechnology develops treatments for infectious diseases and oncology, leveraging immunology-focused scientific capabilities.

AI & Machine LearningBiotechDigital HealthMedical DevicesSan Francisco, US

Marianne De Backer(CEO)inHerbert Virgin(Executive Officer)Howard Horn(Executive Officer)inAlex Bangs(Executive Officer)inMarianne De Backer, M.Sc., Ph.D., MBA(President, Chief Executive Officer and Director)

BoardGeorge Scangos(Executive Officer, Director)

Co-investorsARCH Venture PartnersGV (Google Ventures)SoftBank Vision Fund8VCALTITUDE LIFE SCIENCE VENTURESDCVC (Data Collective)+1 more

CuraSen Therapeuticscurasen.cominOct 2018✓ verified

CuraSen Therapeutics is a privately funded biopharmaceutical company developing treatments that selectively activate adrenergic receptors in the brain to restore noradrenergic signaling.

BiotechHealthtechSan Carlos, US

Anthony Ford(Executive Officer, Director)inBenjamin Potter(Executive Officer)Henry Skinner(Director)Liam Ratcliffe(Director)in

BoardRon Hunt(Director)inLoretta Tse, Ph.D.(Director)

Co-investorsLongitude Capitalabrdn plcIntermediate Capital GroupJohnson & Johnson Innovation – JJDCNew Leaf Venture PartnersPappas Capital+2 more

Allakos Incallakos.comDec 2012 · $10M

Portfolio company that completed a successful 2018 biotech IPO, resulting in a 9x return for RiverVest.

BiotechSan Carlos, US

Nenad Tomasevic(Executive Officer)Christopher Bebbington(Executive Officer, Director)Alejandro Dorenbaum(Executive Officer)

BoardJohn McKearn(Director)inPeter Moldt(Director)

Board seatDan JanneyFarah Champsi· per SEC Form D

Co-investorsLifeSci Venture PartnersNew Enterprise Associates (NEA)RiverVest Venture PartnersSamsara BioCapitalRoche Venture Fund

Calthorpe AnalyticsinSep 2017SEC filingmedium confidence

Berkeley, US

Peter Calthorpe(Executive Officer, Director)in

Board seatGarrett Gruener· per SEC Form D · $2M raise · filed Jul 2019

Krystal Biotechkrystalbio.comin𝕏Aug 2017SEC filingmedium confidence

Krystal Biotech discovers, develops, and commercializes genetic medicines, including gene therapy programs for rare diseases such as dermatological conditions.

BiotechHealthtechMedical DevicesPittsburgh, US

Suma Krishnan(President, Research & Development)inKrish Krishnan(Chairman & CEO)inDoug Norby(Director)Dino Rossi(Director)

Board seatDan Janney· per SEC Form D · $11.3M raise · filed Aug 2017

Co-investorsAvoro Capital AdvisorsFrazier Life Sciences

Progentos Therapeuticsprogentos.comMay 2024 · $65M

Progentos develops small-molecule therapeutics to stimulate myelin regeneration in multiple sclerosis patients by activating oligodendrocyte progenitor cells.

BiotechDeep TechMedical DevicesWatertown, US

Dmitrij Hristodorov(Director)inChristopher Loose(Executive Officer, Director)Sanjay Magavi(Executive Officer)Marc-Olivier Turgeon(Director)in

BoardAleks Radovic-Moreno(Director)in

Board seatDan Janney· per SEC Form D

Co-investorsDolby Family VenturesLongwood FundMission BiocapitalService Provider CapitalForbion

Prolactaprolacta.comin𝕏Nov 2016

Prolacta Bioscience manufactures 100% human milk-based nutritional products and fortifiers for premature and critically ill infants in hospital neonatal intensive care units.

BiotechHealthtechMedical DevicesCity Of Industry, US

Scott Elster(Executive Officer, Director)inJohn M. Shields(Executive Officer)in

BoardFrank Foster(Director)Martin Sutter(Director)David Brailer(Director)

Board seatDan Janney· per SEC Form D

Co-investorsAisling CapitalEssex Woodlands Healthcare PartnersFrontier Venture CapitalPROOF

Spiral Therapeuticsspiraltx.cominDec 2018SEC filingmedium confidence

Spiral Therapeutics is a clinical-stage pharmaceutical company developing therapies for balance disorders and hearing loss using its Minimally Invasive Cochlear System (MICS) drug delivery platform.

BiotechDigital HealthHealthtechMedical DevicesSouth San Francisco, US

Hugo Peris(Founder & CEO)inEugene de Juan(Executive Officer, Director)Lawrence Fritz(Director)

BoardWARREN THALER(Director)JEAN-FREDERIC PAULSEN(Director)

Board seatGuy Nohra· per SEC Form D · $10.9M raise · filed Feb 2023

Co-investorsCatalio Capital ManagementInveready Technology Investment GroupLifelinkStartXCamden PartnersEsperante Ventures

Usgi Medicalusgimedical.cominFeb 2019SEC filingmedium confidence

USGI Medical develops endoluminal medical devices that enable surgical procedures without incisions, targeting healthcare providers and patients seeking less invasive treatment options.

HardwareHealthtechMedical DevicesSan Clemente, US

Tracy Maahs(Executive Officer)inScott Moonly(Executive Officer, Director)inJohn Cox(Executive Officer)in

BoardMike Chuisano(Director)George Abi-Chahine(Director)

Board seatGuy Nohra· per SEC Form D · $4M raise · filed Jun 2019

Aerie Pharmaceuticalsaeriepharma.cominSep 2014

Aerie Pharmaceuticals develops ophthalmic pharmaceutical products including Rocklatan and Rhopressa for glaucoma and ocular hypertension, and AR-15512 for dry eye disease.

BiotechHealthtechMedical DevicesBedminster, US

CASEY KOPCZYNSKI(Executive Officer)inVICENTE ANIDO(Executive Officer, Director)BRIAN LEVY(Executive Officer)RICHARD RUBINO(Executive Officer)THOMAS MITRO(Executive Officer)David Endicott(CEO of Alcon)in

Co-investorsAvoro Capital AdvisorsForesite CapitalOUP (Osage University Partners)Sofinnova Ventures

Amplitude Txamplitude-tx.com

Amplitude Therapeutics is a biotechnology company developing RNA-based medicines.

Biotech

Ark PESarkpes.com

Ark provides a customizable digital platform for venture capital and private equity firms to manage investor communications, performance reporting, and document sharing with their limited partners.

Enterprise SoftwareFintechSaaS

Co-investorsAcies InvestmentsAloft VCAmity VenturesArtis VenturesAsymmetric Capital PartnersAt One Ventures+21 more

Bettervetbettervet.comin

Boston, US

Dan Adams(Executive Officer, Director)

BoardPete Hudson(Director)inBruce Herzfelder(Director)Mark Prather(Director)

Bioventusbioventus.comin𝕏

Bioventus develops and markets medical devices for active healing, including pain management, restorative therapies, and surgical solutions that aim to enhance the body's natural healing processes and reduce the need for invasive procedures.

BiotechDeep TechHealthtechMedical DevicesDurham, US

Robert Claypoole(Chief Executive Officer)

Co-investorsAmpersandEssex Woodlands Healthcare Partners

Calistoga Pharmaceuticalscalistogapharma.comMay 2009 · $30M

Calistoga Pharmaceuticals is a pharmaceutical company.

BiotechHealthtechSeattle, US

Co-investorsFrazier Life SciencesAmgen VenturesFrazier Healthcare Partners

Chimerixchimerix.com𝕏Jul 2019

Chimerix is a biopharmaceutical company developing therapies for rare diseases and cancers, with a focus on advancing treatments through biomarker-driven approaches and precision medicine.

BiotechHealthtechMedical DevicesDurham, US

Mike Sherman(Chief Executive Officer and President)W. Garrett Nichols(Chief Medical Officer)Michael A. Alrutz(Executive Officer)Randall Lanier(Chief Science Officer)Roy W. Ware(Chief Manufacturing and Technology Officer)Heather Knight-Trent(Vice President of Regulatory Affairs)

Co-investorsAisling CapitalAsset Management CompanyCanaan PartnersFrazier Life SciencesPappas CapitalSanderling Ventures

DEM BioPharmadembiopharma.com

DEM BioPharma is a biotechnology company developing cancer therapies by targeting the immune system, drawing on genetic and immuno-oncology research.

BiotechHealthtechCambridge, US

Nenad Grmusa(Chief Executive Officer)inJohn McCabe(Chief Financial and Operating Officer)in

Co-investorsAstellas Venture Management LLCDC Investment PartnersLongwood FundPfizer Venture InvestmentsUTokyo Innovation Platform Co. Ltd.Insight Partners+1 more

Dispatch Healthdispatchhealth.comin

DispatchHealth delivers in-home medical care and house call services, offering patients an alternative to emergency rooms and urgent care facilities for acute medical conditions.

Digital HealthHealthtechDenver, US

Dr. Mark Prather(Founder)Kevin Riddleberger(Founder)inDominic Bagnoli(Director)Mark Prather(Founder)

BoardPete Hudson(Director)in

Co-investorsEcho Health VenturesOak HC/FTOptum VenturesQuesta CapitalSINEWAVE VENTURESTiger Global Management

Edgewood Oncology, Inc.edgewoodoncology.comin

Edgewood Oncology is a clinical-stage biotechnology company developing BTX-A51, a first-in-class treatment candidate for hematologic malignancies and genetically-defined solid tumors.

BiotechHealthtechMedical Devices

Yinon Ben-Neriah(Scientific Founder)David N. Cook(Chief Executive Officer)inZung Thai(Chief Medical Officer)in

eGenesisegenesisbio.comin

eGenesis uses gene editing and genome engineering to develop porcine donor animals for cross-species organ transplantation, addressing organ failure treatment and transplant supply constraints.

BiotechDeep TechMedical Devices

Mike Curtis, Ph.D.(President & Chief Executive Officer)George M. Church(Founder)Luhan Yang(Founder)

Co-investorsAltium CapitalEisai Innovation, Inc.Fresenius Medical Care VenturesKhosla VenturesLux CapitalARCH Venture Partners

eGenesisegenesis.comFeb 2021

Biotechnology company using multiplex gene editing to develop genetically engineered porcine organs for human transplantation.

BiotechBrookline, US

Luhan Yang(President, Secretary and Treasurer)Geoff MacKay(Chief Executive Officer)

BoardGeorge M. Church(Director)

Co-investorsARCH Venture PartnersCatalio Capital Management, LPHBM Healthcare InvestmentsHBM PartnersKhosla VenturesLifeSci Venture Partners+12 more

Esperion Therapeuticsesperion.comJun 2014

Biopharma developing HDL-C regulating therapies; listed 2000.

BiotechAnn Arbor, US

Roger S. Newton(Director)inTim M. Mayleben(Executive Officer, Director)

BoardDaniel Janney(Director)Dov A. Goldstein(Director)Nicole Vitullo(Director)inPatrick Enright(Director)in

PartnerDan Janney· led

Co-investorsAisling CapitalArboretum VenturesARCHIMED JapanAsset Management CompanyCanaan PartnersHealthCap+3 more

Eversideeverside.comin

Everside is a venture capital and investment firm that manages portfolios and provides investment operations, analytics, and advisory services.

Enterprise SoftwareFintechSector Agnostic

Moritz Poehl(Founder, Managing Partner)inNate Kirk(Founder, Managing Partner)in

Co-investorsInterplay Ventures Early Stage Management LlcEndeavor CatalystNew Enterprise Associates (NEA)Oak HC/FT

Everside Healthmarathon.healthinJul 2022

Marathon Health provides advanced primary care combined with lifestyle and chronic condition management for employers and health plans, using health coaches and registered dietitians alongside providers.

Digital HealthHealthtechWellness & Fitness

Dr. Jeff Wells(Founder)

Co-investorsHercules Capital, Inc.New Enterprise Associates (NEA)Sixty Degree CapitalEndeavor CatalystOak HC/FT

Free Market Healthfreemarkethealth.comin𝕏Nov 2023 · $20M

Free Market Health operates a care-driven marketplace platform for the specialty pharmacy ecosystem.

B2B MarketplacesHealthtechSaaSPittsburgh, US

Joe Cardosi(Founder)in

Co-investorsQuesta Capital

Harborrunharbor.comin𝕏Sep 2025 · $130M

Harbor provides electronic data capture (EDC) software for clinical trial teams, designed to reduce data entry time and enable remote monitoring to improve data quality and accelerate trial timelines.

HealthtechMedical DevicesSaaSSan Francisco, US

Albert Cai(CEO)inNathan H. Leung(CTO)inArisa Amano(Founder)Bob Remeika(Founder)

Co-investors8VCCore Venture CapitalY CombinatorCommit CapitalDFOFuture Perfect Ventures+5 more

Harborharborplan.cominSep 2025 · $130M

Harbor Plan provides automation software for independent professionals to manage their practices.

AI & Machine LearningFintechSaaSSales TechSan Francisco, US

Clinton A.(Managing Director)inRob Carrington(Head of Engineering)in

Co-investorsTechstarsTinySeed8VCDFOGeneral Catalyst

Harborharbor.com𝕏Sep 2025 · $130Macquired by BitGo

Crypto & Web3Enterprise SoftwareFintechSioux Falls, US

Co-investorsAndreessen HorowitzFuture Perfect VenturesKindred VenturesPantera CapitalSignia Venture Partners8VC+3 more

Harborharbor.co𝕏Sep 2025 · $130M

Harbor provides sleep training and infant care services for parents and families seeking better sleep and wellness support.

AI & Machine LearningConsumerHardwareHealthtechIoTWellness & Fitness

Kelly Brown(Director of Nursing)Lindsey Sullivan(Chief Marketing Officer)

Co-investorsCarnrite Ventures8VCDFOGeneral CatalystTrust Ventures

Harbor Healthharborhealth.comin𝕏Nov 2025 · $130M

Harbor Health is a healthcare provider and insurance company operating clinics across Texas that offers primary care, specialty care, and health coaching alongside integrated insurance coverage.

HealthtechInsurTechAustin, US

Sterling Claiborne Johnston(Chief Medical Officer)Jeffrey Fisher(Chief Financial Officer)Eric Scott(Vice President)inKara Rios(Chief Financial Officer)inClay Johnston(Founder)Tony Miller(Founder)

Co-investors8VCCubit CapitalGeneral CatalystHealth2047 Capital Partners LLCLemhi VenturesMartin Ventures+2 more

Immune Designimmunedesign.com𝕏Jul 2010 · $32MAcquired

Immunotherapy oncology company engineering technologies to activate the immune system; acquired by Merck in February 2019 for $0.3B.

BiotechHealthtechMedical DevicesSeattle, US

David Baltimore(Director)Carlos V. Paya(Executive Officer, Director)Stephen R. Brady(Executive Officer)inJan Henrik ter Meulen(Executive Officer)Paul Rickey(Executive Officer)inWayne Gombotz(Executive Officer)in

Co-investorsAisling CapitalAtlas VentureHM Venture PartnersOUP (Osage University Partners)Sanderling VenturesSanofi Ventures+4 more

Intarcia Therapeuticsintarcia.comMar 2007 · $50M

Biopharmaceutical company developing innovative therapies for chronic diseases using proprietary drug delivery systems.

BiotechBoston, US

James Ahlers(Executive Officer)John Yee(Executive Officer)Sunita Zalani(Executive Officer)Raymond T. Keane(Executive Officer)Thomas Alessi(Executive Officer)Owen Hughes, Jr.(Executive Officer)

Co-investorsBay City CapitalCloudStone CapitalCycad Group LLCForesite CapitalMarkerNXT Ventures+3 more

Keloniatxkeloniatx.com

Kelonia is a biotechnology company developing next-generation genetic medicines, with a focus on cell and gene therapy programs including in vivo approaches and oncology applications.

BiotechHealthtech

Kevin Friedman(Founder & Chief Executive Officer)in

Co-investorsHorizons Ventures

Kite Pharmakitepharma.cominApr 2014

Kite develops CAR T-cell therapies that engineer a patient's own immune cells to target and destroy cancer cells.

BiotechHealthtechSanta Monica, US

Arie S. Belldegrun(Executive Officer, Director)inMargo R. Roberts(Executive Officer)Cynthia Butitta(Executive Officer)inMarc Better(Executive Officer)inRizwana Sproule(Executive Officer)inArie Belldegrun(Founder)

Co-investorsPontifax Venture CapitalVida Ventures

Lassen Therapeuticslassentherapeutics.cominJan 2024 · $85M

Lassen Therapeutics is a biotechnology company developing therapeutics targeting IL-11, with a pipeline focused on immune and fibrotic diseases.

Biotech

David King(Co-Founder & CSO)inMaria Fardis(CEO)inCadmus C. Rich(Chief Medical Officer)inElaine Stracker(General Counsel)in

Co-investorsCatalio Capital Management, LPDC Investment PartnersFrazier Life SciencesLongitude CapitalLongwood FundBiotechnology Value Fund+2 more

Marathon Healthmarathon-health.comin

Marathon Health provides an advanced primary care model to employers through onsite, nearsite, network, and virtual health centers, aiming to improve employee health and lower healthcare costs.

Digital HealthHealthtechWellness & Fitness

Jerry Ford(Founder)Rick Ennis(Founder)

Co-investorsGeneral AtlanticNew Enterprise Associates (NEA)Oak HC/FTPotentum PartnersSixty Degree Capital

Mbracetrxmbracetrx.comin

mBrace Therapeutics is a therapeutics company focused on drug development, led by executives with backgrounds in oncology and pharmaceutical business development.

BiotechHealthtech

Jay(Executive (former VP, Head of BD&A at AbbVie))Isan Chen(Founder)Renata Pasqualini(Founder)Wadih Arap(Founder)

Co-investorsVenrock

Novome Biotechnologiesnovomebio.comNov 2016 · $33M

South San Francisco biotech engineering commensal gut bacteria into controllable live therapeutics for chronic diseases.

Daly City, US

Weston Whitaker(Executive Officer, Director, Promoter)William DeLoache(Director)Samuel Smits(Director)

BoardElizabeth Stanley(Director)

Co-investorsCerity Partners VenturesColorcon Ventures5AM VenturesAlexandriaDCVC (Data Collective)DCVC Bio+2 more

Paladinahealthpaladinahealth.cominacquired by Marathon Health

Digital HealthHealthtechWellness & Fitness

PatientsLikeMepatientslikeme.comin𝕏May 2015

PatientsLikeMe is a digital health platform where over 850,000 members with various health conditions share experiences and insights to help each other manage their health.

Digital HealthHealthtechSocialCambridge, US

Philippe Amouyal(Director)Jonathan White(Director)Justin Barstein(Director)Martin Coulter(Executive Officer, Director)Jay M. Tenenbaum(Director)Stephen Heywood

Co-investorsOptum Ventures

Qihan Biotechqihanbio.com

Hangzhou-based gene-editing biotech developing immune-privileged cell therapies and xenogeneic organs for transplant and cancer.

Hangzhou, CN

Luhan Yang, PhD(Co-Founder and Chief Executive Officer)George Church, PhD(Co-founder and Co-Chair of Qihan scientific advisory groups)

Co-investorsARCH Venture PartnersLAVSequoia Capital

ROME Therapeuticsrometx.comSep 2021

Boston-based biotech developing drugs against the 'dark genome'/repeatome for autoimmune disease, cancer and neurodegeneration.

Benjamin Greenbaum(Founder)David Ting(Founder)Rosana Kapeller(Founder)

Co-investorsAndreessen HorowitzARCH Venture PartnersGV (Google Ventures)Luma GroupSanofi VenturesAbingworth+11 more

SciTherascithera.bio

Brendan Eckelman(Founder)

Co-investorsVenrock

Transcarenttranscarent.cominMay 2024 · $126M

Transcarent operates a generative AI-powered health and care platform that combines medical, pharmacy, and point solutions into a single member experience, helping people navigate the healthcare system and access on-demand care.

AI & Machine LearningDigital HealthHealthtechDenver, US

Glen Tullman(Founder)in

Co-investors7wire VenturesCorewell Health VenturesGeneral CatalystGeodesic CapitalGreatPoint VenturesHuman Capital+9 more

United Musculoskeletal Partnersumpartners.comin𝕏

UMP is a musculoskeletal (MSK) managed service organization that partners with independent physicians to handle administrative operations while preserving clinical autonomy.

Digital HealthEnterprise SoftwareHealthtechAtlanta, US

Raj Bholé(Founding Physician Director)

Co-investorsWCAS

Variant Biovariantbio.comin𝕏

Variant Bio is a therapeutics company that uses human genomics to guide drug development, drawing on expertise across genetics, molecular biology, therapeutics, anthropology, and ethics.

AI & Machine LearningBiotechDigital HealthNew York, US

Kaja Wasik(Founder)inAndrew Farnum(Founder)inStephane Castel(Founder)inCraig Basson(Chief Medical Officer, President of R&D)inHolly Vance(Chief Operating Officer)in

BoardJulie Sunderland(Director)

Co-investorsGeneral CatalystLux CapitalSoftBank Vision FundDimension Capital

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

Carbylan TherapeuticsKelonia TherapeuticsVertiFlexAlly TherapeuticsAmplitude Therapeutics, Inc.BE BiopharmaBebiopharmaCellective TherapeuticsCoTherixCuteraDEM BioFlamel TechnologiesFoldRx PharmaceuticalsGenePeeksILEX OncologyImmuneIDImmuneidrxInterMune PharmaceuticalsKeloniaKosan BiosciencesMBraceProgentosSwedish Orphan Biovitrum (Sobi)U3 PharmaUnited Musculoskeletal Partners HoldingsVirobay

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

Exits · 10

3 IPOs · 7 acquisitions · showing 9

TransMedicsNASDAQ: TMDXTYRA BiosciencesNASDAQ: TYRAVirNASDAQ: VIRCellective Therapeuticsacq. by MedImmuneHarboracq. by BitGoInterMune Pharmaceuticalsacq. by RocheKosan Biosciencesacq. by Bristol Myers SquibbPaladinahealthacq. by Marathon HealthU3 Pharmaacq. by Daiichi Sankyo

Portfolio news

latest coverage across their companies

Fund performance · per public LP disclosures · 7

as of Sep 2024
FundVintageCommittedNet IRRTVPIDPI
Alta Partners VIIILPs: Employees' Retirement System of Rhode Island, Hawaii Employees' Retirement System2006—16.3%2.47x2.47x
Alta BioPharma Partners IIILPs: Employees' Retirement System of Rhode Island2003—5.8%1.50x1.42x
Alta BioPharma Partners II, L.P.LPs: California Public Employees' Retirement System2000—3.2%1.18x0.96x
Alta Subordinated Debt Partners IIILPs: The Regents of the University of California1993—28.8%3.40x3.40x
Alta Subordinated Debt Partners IILPs: The Regents of the University of California1988—12.1%2.12x2.12x
Alta Subordinated Debt PartnersLPs: The Regents of the University of California1986—8.6%1.88x1.88x
Alta Co PartnersLPs: The Regents of the University of California1980—13.6%2.22x2.22x

Source: public limited-partner disclosures (CalPERS, CalSTRS). Net IRR / TVPI / DPI as reported by the limited partner; a fund's early-year IRR is an interim estimate (J-curve).

IPO stake values · per SEC filings

Value of this firm's stake in each portfolio company at its IPO price, from the prospectus principal-stockholder table.

CompanyOwnedIPO priceAt IPOStake value
TYRA Biosciences9.6%$16.00Sep 2021$62.8M

Source: SEC S-1 / 424B prospectus filings. Stake value = shares beneficially owned × the initial public offering price, as disclosed — a market value at IPO, not a return multiple (the firm's original cost is not disclosed).

Frequently asked questions

How many investments has Alta Partners made?
Alta Partners has 74 tracked investments, 10 of which have exited, including 5 dated in the last 24 months.
What stage does Alta Partners invest at?
Alta Partners invests at the Seed, Series A stages.
What is Alta Partners's typical check size?
Alta Partners typically writes checks of $1M – $12M.
What sectors does Alta Partners focus on?
Alta Partners focuses on Biotech, Digital Health, Healthtech, Longevity, Medical Devices.
Where is Alta Partners located?
Alta Partners is headquartered in Jackson, US.
Who does Alta Partners co-invest with?
Alta Partners most often shares deals with Longwood Fund, ARCH Venture Partners, Frazier Life Sciences, among 101 tracked co-investors.

Media · Podcasts & interviews

featuring the team

Pete Hudson, Alta Partners & Transcarent Investor, Part 1

The Health Care Blog's Channel · Pete Hudson

Jean Deleage - Alta Partners 2 5 2000

FRENCH AMERICAN TV ARCHIVES · Jean Deleage · youtube.com

Images

Alta Partners photo

Co-investors · 17

Longwood Fund

Longwood Fund is a venture capital firm that creates and invests in novel healthcare companies developing new treatments for patients, drawing on its partners' company-building and operating experience.

General Catalyst

General Catalyst is a venture capital firm operating as a partnership focused on company building and accelerating the growth of the businesses it backs.

$30M
Aisling Capital

Aisling Capital is an investment firm focused on companies developing and commercializing innovative healthcare products, services, and technologies.

Canaan Partners

Canaan Partners is a venture capital firm with over 30 years of history, backing companies across technology and healthcare sectors through close, hands-on partnerships with founders.

$500K – $20M
Frazier Healthcare Partners

Frazier Healthcare Partners is a healthcare-focused private equity firm that partners with profitable, growing healthcare companies to drive scale and long-term value, pairing high-conviction investment themes with experienced executives.

$50M – $400M
DCVC (Data Collective)

DCVC (Data Collective) is a deep tech venture capital firm that backs entrepreneurs using computational approaches to solve large-scale real-world problems across many industries.

$5M – $25M
S32

S32 is a venture capital firm investing at the frontiers of technology, backing exceptional founders with conviction-based investing led by experienced partners.

Both backed · 2
5AM Ventures

5AM Ventures is a life science venture capital firm founded in 2002 that funds and builds next-generation life sciences companies, focusing on biopharmaceuticals, drug delivery technologies, and life science instruments.

$100K – $4M
Questa Capital

Questa Capital is a healthcare-focused investment firm that partners with medical device, healthcare technology, and healthcare services companies to help them build transformative businesses and drive change in healthcare.

$15M – $40M
Insight Partners

Insight Partners is an investment firm focused on accelerating revenue and profit growth in software companies, providing capital and operational support through its Insight Onsite team.

Both backed · 1
$120M – $350M
Forbion

Forbion is a global venture capital firm focused on advancing biotech innovations and other sustainable solutions aimed at improving human and planetary health.

Both backed · 1
RiverVest Venture Partners

RiverVest Venture Partners is a life sciences venture capital firm that invests in biotechnology and medical companies, working with entrepreneurs to advance therapeutic and medical innovations.

Both backed · 1
$500K – $3M
▶5 more co-investors

Astellas Venture Management LLCUnknown VenturesPolaris PartnersDomain AssociatesAsset Management Ventures

Firms observed investing alongside Alta Partners, from public investor directories. Shared companies are the overlap with Alta Partners's recorded portfolio.

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