How many investments has Braidwell made?

Braidwell has 8 tracked investments, 3 of which have exited, including 5 dated in the last 24 months.

What sectors does Braidwell focus on?

Braidwell focuses on Biotech, Digital Health, Healthtech.

Where is Braidwell located?

Braidwell is headquartered in Stamford, US.

Braidwell

Venture studio

Stamford · 9 people tracked

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Zachary Leach71 people can intro you

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Investment thesis

A firm that builds and backs companies focused on transforming human health through investment and operational support.

Invests inBiotech Digital Health Healthtech New York Stamford

Source: firm website, verified Sep 29, 2026.

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Stamford, NY, US

Instruments

Equity

Founded

1998

Last 12 months

4 investments

AUM

$3.6B

Tracked investments

Unicorns

IPOs

Team · 9 people

from the firm's website & curated & public directories

Alex Karnal· Chief Investment Officer· Stamford, Connecticut, United Statesin

Alex Karnal is Co-Founder and Chief Investment Officer at Braidwell, where he leads the investment team, and in 2022 co-founded Braidwell Labs, which conducts due diligence and supports the development of new technologies and medicines. From 2005 to 2021, he was a Partner, Managing Director, and Co-Portfolio Manager at Deerfield Management, and he has held board roles with organizations including the Biotechnology Innovation Organization, the Museum of Science, the Children's Health Fund, and The Institute for Life Changing Medicines, which he co-founded. He holds a B.S. from the Massachusetts Institute of Technology and an M.S. from Johns Hopkins University.

Brian Kreiter· Chief Executive Officer· Stamford, Connecticut, United Statesin

Brian Kreiter is Co-Founder and Chief Executive Officer of Braidwell and, in 2022, co-founded Braidwell Labs, which conducts bench-side due diligence and functions as a discovery and launch engine for new technologies and medicines. He previously served as Chief Operating Officer of Bridgewater Associates, where he was a member of the Board of Directors, Chief of Staff to founder Ray Dalio, and Department Head of both Client Service and Investment Research; he also chaired the board of Elemental Cognition and earlier worked as a consultant at McKinsey & Company. He co-founded the nonprofits LIFT in 1998 and NeighborShare in 2020, holds a B.A. from Yale University and an M.B.A. from Harvard Business School, and received the 2004 National Jefferson Award for Public Service.

Zachary Leach· Co-Founder and Chief Investment Officer· Boston, Massachusetts, United Statesin

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Adam Greene· Partner· New York, New Yorkin

Narendra Nayak· Partner· New York, New Yorkin

Jonathan Lee· Partner· New York, New Yorkin

Alexander Karal· Executive Officer

Colin Bettison· Executive Officer· New York, New York, United Statesin

Manish Mital· Executive Officer

What they invest in

from 7 of 8 portfolio companies

Biotech ×5AI & Machine Learning ×4Healthtech ×4Deep Tech ×2Consumer ×1Gaming ×1Hardware ×1Medical Devices ×1

HQs:United States×6

Investments · 8 tracked

founders shown can be your intro path

By year:2026 · 3 2025 · 2 2022 · 16 dated

Bicara Therapeuticsbicara.com in 𝕏NASDAQ: BCAX

Bicara Therapeutics is a clinical-stage biopharmaceutical company developing bifunctional antibody therapies that combine tumor-targeting with immune-modulating payloads to treat solid tumors.

Ivan Hyep(Chief Financial Officer and Treasurer)inLara Meisner(Chief Legal Officer, Compliance Officer and Corporate Secretary)in David Raben(Chief Medical Officer)in

Co-investorsAisling Capital Eight Roads Ventures F-Prime Capital Foresite Capital Premji Invest RA Capital +5 more

Caris Life Sciencescarislifesciences.com in 𝕏NASDAQ: CAIApr 2025 · $168M

Caris Lifesciences operates a precision oncology platform that analyzes DNA, RNA and proteins across tissue and blood to profile a patient's cancer and match treatments and clinical trials.

AI & Machine LearningBiotechHealthtech

David Dean Halbert(Chairman, Founder and CEO)

Co-investorsCoatue Management Silver Lake Partners Sixth Street Millennium Management OrbiMed

Relmada Therapeuticsrelmada.comNASDAQ: RLMDMar 2026

Relmada is a clinical-stage biopharmaceutical company developing therapies including NDV-01, a sustained-release intravesical formulation of gemcitabine and docetaxel for non-muscle invasive bladder cancer, and Sepranolone, a candidate targeting compulsive behaviors via GABAA receptor modulation.

BiotechHealthtechNew York, US

Sergio Traversa(Executive Officer, Director)Paul Kelly(Director)Maged Shenouda(Director)in Eliseo O. Salinas(President and Chief Scientific Officer)inDouglas Beck(Chief Financial Officer)Charles Ence(Chief Accounting and Compliance Officer)

Co-investorsBioAdvance BAM Elevate Commodore Capital Janus Henderson Investors OrbiMed RA Capital +2 more

Impulse Dynamicsimpulse-dynamics.com in 𝕏Dec 2025 · $158M

Impulse Dynamics develops implantable medical device technology for cardiac care, with a background in biomedical research and implantable cardiac electronics.

BiotechHardwareHealthtechMedical DevicesDublin 2, US

Shlomo Ben-Haim(Director)Jason Spees(Chief Executive Officer)in Paul Bae(Chief Administrative Officer and General Counsel)in David Prutchi(Executive Vice President, Chief Technology Officer)inRichard J. Buchholz(Chief Financial Officer)Anthony Hong(Chief Science and Strategy Officer)in

Co-investorsAmzak Health Alger Essex Woodlands Healthcare Partners REDMILE Sands Capital Ventures Signet Healthcare Partners

Nabla Bionabla.bio in 𝕏Series B

Nabla is a drug development company that applies design discipline and scientific rigor to the development of new medicines.

AI & Machine LearningBiotechDeep TechHealthtechBoston, US

Surge Biswas(Founder)in Frances Anastassacos(Founder)in

Co-investorsCantos Ventures Fifty Years Petri Pillar VC Radical Ventures Y Combinator +5 more

Prompt AIpromptai.coJan 2026 · $80M

Prompt is an Ambient AI product and research company that develops human-centered AI products designed to sense the physical environment.

AI & Machine LearningConsumerDeep TechSan Francisco, US

Tete Xiao(Founder)in

Co-investorsAbstract Ventures AIX Ventures DCVC (Data Collective)Neotribe Ventures Alexandria CDP Venture Capital +4 more

Proximaproxima.ggJan 2026 · $80M

Proxima develops AI-powered gaming experiences and infrastructure, with a focus on embodied AI agents and applied AI systems for interactive entertainment.

AI & Machine LearningGamingSan Francisco, US

Ran Mo(Founder)in

Co-investorsKonvoy Ventures Progression AIX Ventures Alexandria Balderton Capital Bayern Kapital +9 more

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

Perceive Biotherapeutics

Exits · 3

3 IPOs

Bicara TherapeuticsNASDAQ: BCAXCaris Life SciencesNASDAQ: CAIRelmada TherapeuticsNASDAQ: RLMD

Portfolio news

latest coverage across their companies

Caris Life Sciences Launches New National Commercial Featuring Kevin Costner to Raise Awareness of Early Cancer Detection and Caris Detect

Caris Life Sciences · finance.yahoo.com · Sep 8, 2026

Impulse Dynamics Completes $158M Financing Round

Impulse Dynamics · globenewswire.com · Dec 10, 2025

Frequently asked questions

How many investments has Braidwell made?: Braidwell has 8 tracked investments, 3 of which have exited, including 5 dated in the last 24 months.
What sectors does Braidwell focus on?: Braidwell focuses on Biotech, Digital Health, Healthtech.
Where is Braidwell located?: Braidwell is headquartered in Stamford, US.

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