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The Engine Ventures

Venture capital

Cambridge · Pre-Seed–Series A · 24 people tracked

Also known as FWH MANAGEMENT COMPANY, LLC

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Investment thesis

Engine Ventures focuses on the next generation of Tough Tech founders, investing in companies that unlock large opportunities in foundational industries. Beyond capital, the firm provides operational expertise and access to a network spanning academic, commercial, and governmental institutions to help build and scale these companies.

Source: firm website, verified Aug 11, 2026.

Stage
Pre-Seed–Series A
HQ
Cambridge, Massachusetts, US
Leads rounds
Follows
Instruments
Equity
Founded
2023
Last 12 months
1 investment
AUM
$1.1B
VC funds
10
Tracked investments
80

Team · 24 people

from the firm's website & public directories
Alaina Hartnett· Associatein
Bettina Metais· Vice President of Investor Relations & Operationsin
Ericka Tamayo-Guevara· Analystin
Esha Patel· Financial Analystin
Jen Lichtman· General Counselin
Lena Hansen· Platform Coordinatorin
Lizzie Raymer· Executive Assistantin
Richard Collins· Senior Director of Research & Analyticsin
Sarah Keane· Executive Assistantin
Sophia Cohen· Analystin

What they invest in

from 42 of 80 portfolio companies

Biotech ×18Cleantech ×15Deep Tech ×14Energy ×12AI & Machine Learning ×8Climate Tech ×8Medical Devices ×8New Materials ×8

HQs:United States×33

Investments · 80 tracked

founders shown can be your intro path

By year:2026 · 12024 · 22022 · 22021 · 12019 · 12017 · 18 dated

ISEEisee.aiin𝕏Sep 2017

Cambridge, US

Le Yu(Director)Yibiao Zhao(Executive Officer, Director)

Board seatReed Sturtevant· per SEC Form D

→ Foundation Alloyfoundationalloy.comin𝕏

Foundation Alloy engineers custom metal alloys and components using solid-state processing that avoids melting, enabling microstructures and contaminant control that conventional metallurgy cannot achieve.

Advanced ManufacturingDeep TechNew Materials

Jasper Lienhard(Cofounder)

Addis Energyaddisenergy.comin

Addis Energy develops technology that combines oil and gas engineering expertise with advanced research to access energy and resources from subsurface geology.

CleantechDeep TechEnergy

Amide

Rapid robotic synthesis of valuable peptides and protein structures that can't be manufactured with cells.

Amidetechamidetech.comin

Amide is a peptide synthesis provider that manufactures hard-to-obtain peptides on demand, offering reliable linear synthesis up to 120 amino acids and large full-length proteins via ligation.

Advanced ManufacturingBiotechDeep Tech

Anthologyanthology.bioin

Anthology develops designer and hybrid genomes by decoding genomic "language" to engineer microbes that convert feedstocks such as sugars, plastics, and agricultural waste into products like chemicals, materials, and food ingredients.

BiotechFoodTechNew Materials

Atlantic Qcatlantic-qc.com
Atlantic Quantumatlantic-quantum.comMay 2022

Building scalable quantum computers with reduced complexity and cost to reach error correction at scale.

Cambridge, US

Bharath Kannan(Executive Officer)Simon Gustavsson(Director)

AtmosZeroatmoszero.energyin𝕏
Axiomatic_AIaxiomatic-ai.comin

An MIT spinoff developing AI systems for logical reasoning and prototype development, focusing on semiconductor-based hardware with a goal to achieve tenfold productivity gains by 2030.

Axoftaxoft.usin

Axoft develops soft neural implants and brain-computer interface technology for research and clinical applications.

BiotechDeep TechMedical DevicesCambridge, US

Paul Le Floch(Executive Officer, Director)inRachel Sha(Director)Tianyang Ye(Director)

BoardChia An Lee(Director)Benjamin Pless(Director)

Bexorgbexorg.comin

Bexorg is a biotech platform for CNS drug discovery built on a whole-brain perfusion model that allows manipulation and recording of cellular activity in intact human brains.

AI & Machine LearningBiotechDigital HealthMedical DevicesNew Haven, US

BoardZvonimir VrseljainNenad Sestan

Biobot Analyticsbiobot.ioin𝕏

Biobot pioneers wastewater epidemiology, monitoring pathogens and substances in sewage to provide real-time public health surveillance at the community level.

BiotechData & InfrastructureGovTechHealthtechBoston, US

Newsha Ghaeli(Cofounder & President)inMariana Matus(Founder)inMariana Guadalupe Matus Garcia(Executive Officer, Director)

BoardVivek Pattipati(Director)Andrew Perlman(Director)

Blue Energyblueenergy.coin𝕏Apr 2026

Blue Energy develops scalable small modular reactor (SMR) technology to deliver nuclear power at scale.

CleantechClimate TechDeep TechEnergyHardwareWashington, US

JakeTomJacob Jurewicz(Executive Officer, Director)Thomas O'Neill(Executive Officer, Director)

BoardOrin Hoffman(Director)Michael Kearney(Director)

Boston Metalbostonmetal.comin

Boston Metal develops Molten Oxide Electrolysis (MOE), a platform technology for producing high-value and critical metals from inputs such as low-grade ores, mining waste, and industrial waste.

Advanced ManufacturingCleantechNew Materials

Tadeu Carneiro(CEO)in

Celestial AIcelestial.aiin𝕏

The page describes Photonic Fabric, an optical interconnect technology platform for the scale-up interconnect market that enables high-bandwidth, power-efficient links for AI data center infrastructure.

AI & Machine LearningDeep TechSector AgnosticSemiconductorsSanta Clara, US

Preetinder Virk(Chief Operating Officer)David Lazovsky(President and Chief Executive Officer)Kelyn Brannon(Chief Financial Officer)Philip Winterbottom(Chief Technology Officer)Alexis Bjorlin(Director)

BoardLip-Bu Tan(Director)

Cellino

Curing the world's toughest diseases by automating personalized medicine.

Cellino Biocellinobio.comin

Cellineobio develops cell engineering and bioprocess technology platforms.

AI & Machine LearningBiotechDeep TechMedical DevicesCambridge, US

Nabiha Saklayen, PhD(Co-Founder & CEO)inMarinna Madrid, PhD(Co-Founder & Chief Product Officer)Nabiha Saklayen(Executive Officer, Director)Matthias Wagner(Executive Officer, Director)

BoardKatie Rae(Director)

Commonwealth Fusion Systemscfs.energyin𝕏

Commonwealth Fusion Systems develops commercial fusion power plants using high-temperature superconducting magnet technology to provide grid-scale energy.

CleantechClimate TechDeep TechEnergyCambridge, US

Brandon Sorbom(Founder)Robert Mumgaard(Executive Officer, Director)Daniel Brunner(Executive Officer)Massimiliano Pieri(Director)Alan Eustace(Director)

BoardKatie Rae(Director)

Copernic
Copernic Catalystscoperniccatalysts.comin

Copernic develops catalysts for zero-carbon ammonia and e-fuels that are cost-competitive and compatible with existing industrial infrastructure.

CleantechClimate TechDeep TechEnergyCambridge, US

Jacob Ebenstein Grose(Executive Officer, Director)

BoardLindy Fishburne(Director)Michael Kearney(Director)Michael LoCascio(Director)

DBOSdbos.devin𝕏
DG Matrixdgmatrix.comin

DG Matrix develops the Interport platform, a multi-port solid-state transformer solution that enables software-defined, flexible power distribution for AI data centers, commercial/industrial electrification, EV fleet charging, and utility grid environments.

AI & Machine LearningEnergyHardware

Dropletbioscidropletbiosci.comin𝕏

Droplet has developed a platform to collect and profile patient lymph fluid from routine surgical drain fluid, enabling a lymph-based liquid biopsy.

BiotechHealthtechMedical DevicesMelrose, US

Stanley Lapidus(Director)Theresa Tribble(Executive Officer, Director)Aadel Chaudhuri(Executive Officer, Director)Jose Zevallos(Director)

BoardAnn DeWitt(Director)

Emvolonemvolon.com

Startup cofounded by Emmanuel Kasseris.

Engine Venturesin
EVOLOH

Cheaper, sustainable electrolyzer solution enables hydrogen delivery to the world.

EvolOH +Moreevoloh.comin
Finwavefinwavesemi.comin
Foray BioscienceFeb 2024

Protecting and restoring natural ecosystems, one plant cell at a time.

BiotechCambridge, US

Ashley Beckwith(Executive Officer, Director)

Foraybioforaybio.comin

Foray Bioscience uses single plant cells and AI-powered software (Pando) to direct how plant matter forms, producing plant materials, molecules, and seeds without growing whole plants.

AgTechAI & Machine LearningBiotech

Ashley Beckwith(Founder & CEO)

Form Energyformenergy.comin𝕏

Form Energy develops and manufactures iron-air batteries designed to store energy for up to 100 hours, targeting utility-scale grid reliability and multi-day energy storage.

Advanced ManufacturingCleantechEnergy

Mateo Jaramillo(Founder & CEO)inTed Wiley(Founder)inBilly Woodford(Founder)Yet-Ming Chiang(Founder)inMarco Ferrara(Founder)

Genominesgenomines.comin

Genomines uses biological systems to extract battery-grade nickel from low-grade soils, producing critical metals at lower cost and environmental impact than traditional mining.

BiotechCleantechNew Materials

Dali Rashid(CTO)

Hpcwirehpcwire.com

HPCwire is a news and media outlet covering high performance computing, supercomputing, AI, and related enterprise technology topics for industry professionals.

AI & Machine LearningEnterprise SoftwareMedia & Entertainment

Hyfehyfe.techin

Hyfé refines food waste to extract specialty ingredients and chemical compounds for use in food, beverage, personal care, nutraceutical, and biomanufactured products.

BiotechCircular EconomyFoodTechChicago, US

Michelle Ruiz(Executive Officer, Director)Andrea Schoen(Executive Officer)

Hyfé

Repurposing wastewater into low-cost feedstock to enable biomanufacturing at scale.

Hyfé Foods
HyperLight

Ultra-efficient optical circuits to de-bottleneck data centers and telecom networks.

Hyperlightcorphyperlightcorp.comin
Kano

Enabling precision-genomic editing with single-stranded DNA technology.

Kano Therapeuticskanotherapeutics.comin𝕏May 2024

Kano Therapeutics is a biotech company developing chemical biology platforms aimed at clinical and commercial therapeutic products.

BiotechCambridge, US

Floris Engelhardt(Executive Officer, Director)John Vroom(Director)

BoardAnn DeWitt(Director)

Kytopenkytopen.comin

MIT spin-out offering a customizable multi-solution platform for discovery, development, and manufacturing of cell therapies using non-viral delivery technology.

BiotechCambridge, US

Cullen Buie(Director)Michael Chiu(Director, Executive Officer)Paulo Garcia(Executive Officer, Director, Promoter)

BoardPaxton Major(Director)Ann DeWitt(Director)Paul Wotton(Director)

Lilac Solutionslilacsolutions.comin

Lilac Solutions develops direct lithium extraction technology using ceramic ion exchange media, enabling fast, clean, and affordable lithium production from brines for the electric vehicle and battery industries.

CleantechClimate TechEnergyNew MaterialsOakland, US

David Snydacker(President & Chief Technology Officer)inNicholas Goldberg(Chief Legal Officer of Issuer)Ian Pearce(Director)inDavid Gelinas(Chief Financial Officer of Issuer)inSamuel Romer(Director)Raef Sully(Chief Executive Officer of Issuer)in

Mantelmantelcapture.comin

Mantel Capture, Inc. appears to operate in process engineering and commissioning, with roles referencing boilers, licensing, and research; the page itself provides no explicit statement of the company's product or market.

CleantechClimate TechNew MaterialsCambridge, US

Cameron Halliday(Executive Officer, Director)Danielle Rapson(Executive Officer, Director)Danielle Colson(Cofounder)Sean Robertson(Director)

BoardHooisweng Ow(Director)Michael Kearney(Director)

Matrisome Biomatrisomebio.comin
Morimori.com
Osmosesosmoses.com

Osmoses develops a membrane technology for purifying and separating gas molecules, aimed at making industrial gas separation processes more energy-efficient.

CleantechClimate TechDeep TechNew MaterialsBoston, US

Francesco Benedetti(Co-Founder & CEO)Katherine Mizrahi Rodriguez(Co-Founder & Chief Implementation Officer)Zachary P. Smith(Co-Founder / Associate Professor, MIT)

Ososemiososemi.comin

Oso Semiconductor develops power-efficient, high-performance beamforming chipsets for wireless systems using phased-array (electrically steered) antennas, based on ultra-low-loss beamforming IP.

Defense TechHardwareSemiconductors

Overview EnergySep 2022

Space-based solar power providing 24/7 clean energy

Covina, US

Andrew Cantino(Executive Officer, Director)Marc Berte(Executive Officer, Director)

BoardAnton Brevde(Director)

Pascal

A materials breakthrough to eliminate the climate impact of cooling.

Pascaltechnologypascaltechnology.comin

Pascal develops solid refrigerants for heating, ventilation, and air conditioning systems with zero global warming potential.

Advanced ManufacturingCleantechClimate Tech

Predicta

Using molecular diagnostics to transform the patient experience and unlock novel therapies.

Predictabiosciencespredictabiosciences.comin𝕏

Predicta develops a molecular insights platform for blood cancer care that generates genomic and immune profiling from blood samples to guide treatment decisions and monitor disease evolution.

BiotechDigital HealthMedical DevicesCambridge, US

Pulse2pulse2.comin𝕏
Quaise

Universal access to geothermal energy through disruptive millimeter wave drilling technology.

Quaise Energyquaise.energy

Quaise Energy develops superhot geothermal drilling technology using millimeter-wave powered drilling to access deep geothermal energy sources at unprecedented depths and temperatures for large-scale clean power generation globally.

CleantechDeep TechEnergyHouston, US

Carlos Araque(Executive Officer, Director)Vinod Khosla(Director)William Restrepo(Director)Frohman Anderson(Director)Ali Azad(Director)

BoardColleen Calhoun(Director)

RADLANin𝕏

Marvell designs custom silicon and provides interconnect and network switch products for AI data center infrastructure, serving hyperscalers, enterprises, and telecom carriers.

AI & Machine LearningData & InfrastructureSemiconductors

Resonant Linkresonant-link.comDec 2021

Resonant Link Inc. developed wireless power technology and is no longer operating as an active business, now managing and licensing its patent portfolio for non-medical wireless power.

Deep TechEnergyHardwareMedical DevicesShelburne, US

Grayson Zulauf(Executive Officer, Director)Aaron Stein(Director)Orin Hoffman(Director)

BoardShilpi Kumar(Director)

ReynKo

Applying a fundamental mathematical insight to the problem of turbulence.

Rise Roboticsriserobotics.comin𝕏

RISE Robotics develops RISE® Cylinder, a fluid-free electro-mechanical alternative to hydraulic cylinders for heavy equipment and machinery that uses belt technology to deliver hydraulic-like forces with significantly greater energy efficiency.

Advanced ManufacturingCleantechDeep TechHardwareRoboticsBoston, US

Arron Acosta(Co-Founder, VP of Business Development)Blake Sessions(Co-Founder & Chief Technology Officer)Toomas Sepp(Co-Founder & Chief Engineer)Kyle Dell'Aquila(Co-Founder & Head of Industrial Design & Customer Experience)Hiten Sonpal(Chief Executive Officer)

Portfolio news

latest coverage across their companies

Frequently asked questions

What stage does The Engine Ventures invest at?
The Engine Ventures invests at the Pre-Seed, Seed, Series A stages.
What sectors does The Engine Ventures focus on?
The Engine Ventures focuses on Advanced Manufacturing, AgTech, Biotech, Cleantech, Climate Tech, Consumer, Data & Infrastructure, Deep Tech, Energy, Enterprise Software, FoodTech, Hardware, New Materials, SaaS, Semiconductors.
Where is The Engine Ventures located?
The Engine Ventures is headquartered in Cambridge, US.
Does The Engine Ventures lead rounds?
The Engine Ventures typically participates in rounds rather than leading them.

Images

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