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Septerna

South San Francisco, US · Founded 2019 · 5 known investors

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Septerna is a biotechnology company that uses its proprietary Native Complex Platform to discover and develop oral small molecule therapies targeting GPCRs for endocrinology, immunology and inflammation, and metabolic diseases.

AI & Machine LearningBiotechDeep Tech

Founders & leadership

Septerna was founded in 2019 by Robert Lefkowitz, Arthur Christopoulos, and Patrick Sexton.

RL
Robert LefkowitzFounder
AC
Arthur ChristopoulosFounder
PS
Patrick SextonFounder
RXRan Xiao
Ran XiaoVP, Finance and Business OperationsRan Xiao is an Executive Officer at Septerna, a biotechnology company developing oral small molecule therapies targeting GPCRs. He brings over 20 years of corporate finance experience in life sciences, with expertise in accounting, financial planning, treasury, and regulatory reporting, and has led administrative and financial functions at a venture-backed company through its IPO.
EB
Elizabeth BhattExecutive
SSSamira Shaikhly
Samira ShaikhlyChief People OfficerSamira Shaikhly is Chief HR Officer at Septerna, a biotechnology company developing oral small molecule therapies for endocrinology, immunology, inflammation, and metabolic diseases. She has prior experience in talent management and organizational strategy.

Board

AEAlan Ezekowitz
Alan EzekowitzBoard directorInvestor at Third Rock Ventures
JTJeffrey Tong
Jeffrey TongBoard directorPartner at Third Rock Ventures
JSJake Simson
Jake SimsonBoard directorPartner at RA Capital
AB
Abraham BassanBoard director
JFJeffrey Finer
Jeffrey FinerCEO and Co-FounderVenture Partner at Third Rock Ventures

Investors · 5

RA Capitallisted by RA CapitalBostonvia Jake Simson · board

How we know: RA Capital's portfolio page · board seat on SEC Form D · open dataset · 5k.vc investor directory · Not right? Tell us

Samsara BioCapitallisted by Samsara BioCapitalMenlo Park

How we know: Samsara BioCapital's portfolio page · a partner's Signal profile · Not right? Tell us

Vertex Ventures HClisted by Vertex Ventures HCSingapore · $500K – $10M
Third Rock VenturesreportedBoston · $100K – $5Mvia Jeffrey Tong · board

How we know: a partner's Signal profile · board seat on SEC Form D · open dataset · 5k.vc investor directory · Not right? Tell us

Funding

SEC filings, press & company announcements

$73.5M disclosed across 1 of 3 rounds · 2022–2024

▶$73.5MraisedJul 2023 · 30 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Alan EzekowitzDirector
  • Ran XiaoExecutive Officer
  • Elizabeth BhattExecutive Officer
  • Jeffrey TongDirector
  • Jake SimsonDirector
  • Abraham BassanDirector
  • Jeffrey FinerExecutive Officer, Director
  • Samira ShaikhlyExecutive Officer
Offering amount
$150M
Amount sold
$73.5M
First sale
Jun 2023
Incorporated
Corporation, Delaware, 2019
Federal exemptions
06b
Full filing on SEC EDGAR ↗

Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.

Frequently asked questions

What does Septerna do?
Septerna is a biotechnology company that uses its proprietary Native Complex Platform to discover and develop oral small molecule therapies targeting GPCRs for endocrinology, immunology and inflammation, and metabolic diseases.
Who founded Septerna?
Septerna was founded by Robert Lefkowitz, Arthur Christopoulos, Patrick Sexton in 2019.
Who are Septerna's investors?
Septerna's investors include Catalio Capital Management, LP, RA Capital, Samsara BioCapital, Vertex Ventures HC, Third Rock Ventures.
How much funding has Septerna raised?
Septerna has disclosed $73.5M raised across 1 of its 3 known rounds.
Where is Septerna headquartered?
Septerna is headquartered in South San Francisco, US.