/Investor DB

MPM BioImpact

Venture capitaloperating company · company profile

Boston · Pre-Seed–Late Stage · 51 people tracked

Also known as MPM ASSET MANAGEMENT LLC · MPM Capital

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Investment thesis

MPM BioImpact leverages three decades of biotech venture expertise combined with impact investing principles to support companies across all drug development phases. The firm invests in both private and public biotech companies that aim to meaningfully improve patient outcomes and transform treatment of disease, while maintaining commitment to global impact investment standards.

Source: firm website, verified Sep 29, 2026.

Stage
Pre-Seed–Late Stage
Check
$1M – $15M
HQ
Boston, Massachusetts, US
Instruments
Equity
Founded
1992
Last 12 months
5 investments
AUM
$3.6B
Tracked investments
67
Unicorns
2
IPOs
4
Acquisitions
2

Team · 51 people

from the firm's website & curated & public directories
Chris Bardon· Managing Partner

Managing Partner at MPM BioImpact who led the firm's early public investment in argenx.

Michael Ehlers, M.D.· Board Member
Alan Kelly· Director
Nicole Ramroop· Director

13 people who came through MPM BioImpact went on to found or lead other companies.

+ 1 more →

What they invest in

from 56 of 67 portfolio companies

Biotech ×52Healthtech ×23Medical Devices ×14AI & Machine Learning ×6Digital Health ×6Deep Tech ×4Longevity ×3Consumer ×1

HQs:United States×48United Kingdom×1

Who they back

founder profiles across 12 portfolio companies
42%
solo founders
5 of 12 mapped founding teams
45%
repeat founders
of 11 founders with career history
~3 yrs
old at investment
median across 10 dated deals

Founding team size:solo founder×52 founders×44+ founders×3

Where their founders worked beforefrom 11 founders with career history

Longwood Fund ×3Harvard Medical School ×2Maverick Therapeutics ×2Potenza Therapeutics ×2Trieza Therapeutics ×2Vesuvius Pharmaceuticals ×2

Investments · 67 tracked

founders shown can be your intro path

By year:2026 · 32025 · 52024 · 42023 · 22022 · 22021 · 42020 · 52019 · 52018 · 42017 · 42016 · 42015 · 252 dated

Aktis Oncologyaktisoncology.cominNASDAQ: AKTSSeries A · Oct 2024 · $318M

Aktis Oncology discovers and develops targeted radiopharmaceuticals for treating solid tumors.

BiotechHealthtechMedical DevicesBoston, US

Todd Foley(Co-founder and Chairman)inPatrick Baeuerle(Co-founder & Advisor)inShulamit Ron-Bigger(Executive Officer)inKyle D. Kuvalanka(Chief Financial Officer)inAkos Czibere(Chief Medical Officer)inPaul L. Feldman(Chief Scientific Officer)in

Board seatTodd Foley· per SEC Form D

Co-investorsAndreessen HorowitzEcoR1 CapitalMRL Ventures FundPappas CapitalRA CapitalTCG Crossover+5 more

Entrada Therapeutics, Inc.entradatx.cominNASDAQ: TRDAApr 2021

Entrada Therapeutics is a biotech company developing intracellular therapeutics based on its proprietary EEV Platform, aimed at reaching previously inaccessible or undruggable disease-causing targets inside cells.

BiotechHealthtechBoston, US

Natarajan Sethuraman(Executive Officer)inNerissa Kreher(Executive Officer)inKory Wentworth(Executive Officer)inDipal Doshi(Chief Executive Officer)inNatarajan Sethuraman, PhD(President of Research and Development)Nathan J. Dowden(President and Chief Operating Officer)in

Board seatTodd Foley· per SEC Form D

Co-investors5AM VenturesAgent CapitalMRL Ventures FundRoche Venture FundTCG CrossoverWellington Management

Dyne Therapeuticsdyne-tx.comin𝕏NASDAQ: DYNAug 2020

Dyne Therapeutics develops targeted therapies for genetically driven neuromuscular diseases using its proprietary FORCE platform.

BiotechMedical DevicesWaltham, US

Romesh Subramanian, Ph.D.(Executive Officer)Richard Scalzo(Executive Officer)Joshua Brumm(Executive Officer, Director)Jonathan McNeill, M.D.(Executive Officer)inOxana Beskrovnaya, Ph.D.(Executive Officer)John G. Cox(President and Chief Executive Officer)in

Co-investorsAtlas VentureVida VenturesWellington ManagementForbionHercules Capital, Inc.RA Capital

Syndax Pharmaceuticalssyndax.cominNASDAQ: SNDX

Syndax Pharmaceuticals is a commercial-stage biopharmaceutical company that develops and commercializes small-molecule and antibody cancer therapies, including two FDA-approved medicines: revumenib (a menin inhibitor for acute leukemias) and axatilimab (a CSF-1R blocking antibody for graft-versus-host disease and fibrotic diseases), along with clinical-stage programs exploring expanded uses and combinations in oncology.

BiotechWaltham, US

John Pallies(Executive Officer)inArlene Morris(Executive Officer, Director)inMichael A. Metzger(Chief Executive Officer)inKeith A. Goldan(Chief Financial Officer)in

BoardDennis Podlesak(Director)inIvor Royston(Director)

Co-investorsAisling CapitalATEM Capital FundAvoro Capital AdvisorsBioBritDelos CapitalEcoR1 Capital+6 more

Umoja Biopharma, Inc.umoja-biopharma.comin𝕏Series A · Jun 2021 · $53M✓ verified

Umoja Biopharma develops in vivo CAR T cell cancer therapies using its VivoVec platform, which generates chimeric antigen receptor T cells directly inside a patient's body rather than through the traditional ex vivo process.

BiotechHealthtechSeattle, US

Andrew M. Scharenberg(Executive Officer, Director)Philip S. Low(Director)Andrew Scharenberg(Founder)Michael Jensen(Founder)Philip Low(Founder)Ryan Crisman(Founder)

Board seatLuke Evnin· per SEC Form D

Co-investorsDCVC BioQiming Venture Partners USASoftBank GroupK2 HealthVenturesSoftBank Vision FundAlexandria+2 more

Arialysarialysrx.comin𝕏✓ verified

Arialys Therapeutics develops precision medicines designed to block pathogenic autoantibodies that target brain receptors such as the NMDA receptor, aiming to treat neuropsychiatric disorders driven by autoimmune disease.

BiotechHealthtechLa Jolla, US

Peter Flynn, Ph.D.(Executive Officer, Director)

BoardJay Lichter, Ph.D.(Director)Brian Slingsby, M.D., Ph.D., M.P.H.(Director)Ed Hurwitz(Director)inAshish Xavier, Ph.D.(Director)Tighe Reardon(Executive Officer)

Co-investorsAvalon BioVenturesCatalys Pacific

Fablefabletherapeutics.com✓ verified

Fable Therapeutics is a biotech company using protein engineering to develop biologics targeting the activin receptor type II (ActR2) pathway for obesity and related metabolic diseases.

BiotechHealthtechLongevity

Geoff MacKay(President & CEO)David Baker(Chief Scientific Officer)Rhonda Wideman(Chief Business Officer)Zack McNealy(Chief Financial Officer)

Co-investorsVersant VenturesDCVC BioLilly Asia VenturesDCVC (Data Collective)

Photys Therapeutics, Inc.photys.cominSeries A · Sep 2022 · $75M✓ verified

Photys Therapeutics develops bifunctional small-molecule medicines that use induced proximity to recruit kinases and drive targeted protein phosphorylation, aiming to modulate and repair disease-driving proteins.

BiotechHealthtechLongevityWaltham, US

Amit Choudhary(Scientific Founder)David Steinberg(Chairman & Founding CEO)inEdward Holson(Co-founder & CSO)inLizzie Ngo(Co-founder)inBrian Fenton(President & CEO)in

Co-investorsLongwood Fund8VCMRL Ventures FundOno Venture Investment, Inc.

Tizona Therapeutics, Inc.tizonatx.com✓ verified

Tizona Therapeutics is a biotechnology company developing first-in-class immuno-oncology therapeutics, including its lead clinical-stage asset TTX-080, aimed at changing cancer progression and relapse.

AI & Machine LearningBiotechHealthtech

Vijay K. Kuchroo(Scientific Co-Founder & Advisory Board Member)Drew Pardoll(Scientific Co-Founder & Advisory Board Member)Dario Vignali(Scientific Co-Founder & Advisory Board Member)Jedd Wolchok(Scientific Co-Founder & Advisory Board Member)Christine O'Brien(Chief Executive Officer & Board Member)inCourtney Beers(Chief Scientific Officer)

Co-investorsCanaan PartnersAbingworthGilead SciencesAstellas Venture Management LLCLightstone Ventures

Trishula Therapeutics, Inc.trishulatx.comin✓ verified

Trishula Therapeutics is a clinical-stage biopharmaceutical company developing TTX-030, a first-in-class anti-CD39 antibody for advanced cancers.

BiotechHealthtech

Anil Singhal(President and CEO)inSiddhartha Mitra(Chief Medical Officer)in

Co-investorsCanaan PartnersAstellas Venture Management LLCLightstone Ventures

Vascular Pharmaceuticalsvascularpharma.comDec 2015✓ verified

Vascular Pharmaceuticals develops VPI-2960B, a therapeutic candidate in clinical development for diabetic nephropathy treatment.

BiotechDigital HealthMedical DevicesChapel Hill, US

Laura Maile(Co-Founder, Director, Research and Development)Richard Shea(Executive Officer, Director)inBonnie Layman(Executive Officer)David Clemmons(Co-Founder, Chief Scientific Officer)

BoardElizabeth Stoner(Director)inRichard Kent(Director)

Chiasmachiasmapharma.comSeries C · Dec 2014 · $44M

BiotechNewton Centre, US

Chaime Orlev(Executive Officer)Roni Mamluk(Executive Officer, Director)

BoardScott Minick(Director)inTodd T. Foley(Director)inVincent Miles(Director)Ansbert K. Gadicke(Director)in

Board seatBard GeesamanDavid StackAnsbert Gadicke· per SEC Form D

Co-investorsHEALTHCARE ROYALTY PARTNERSSofinnova VenturesAbingworthARCH Venture Partners

Clinical inkclinicalink.comin𝕏Dec 2017 · $20M

Clinicalink offers a digital tool designed to improve drug adherence and measure the functional quality of weight loss.

Digital HealthHealthtechSaaSWinston-Salem, US

Douglas E. Pierce, Jr.(Executive Officer, Director, Promoter)Joe Schmidt(Executive Officer)Edward S. Seguine(Executive Officer, Director, Promoter)

BoardMatt King(Director)inBrad Geesaman(Director)

Board seatTony RosenbergTodd FoleyAnsbert Gadicke· per SEC Form D

Co-investorsFCA Venture PartnersMcKesson Ventures

Crossbow Therapeuticscrossbowtx.cominSeries A · Sep 2025 · $77M

Crossbow Therapeutics develops TCR-mimetic antibody therapies designed to target cancer antigens by mimicking T-cell receptors, with a focus on treating solid tumors and hematologic malignancies.

AI & Machine LearningBiotechMedical DevicesCambridge, US

Alexander Nolte(Executive Officer)inDmitri Wiederschain(Executive Officer)in

BoardAlexandra Cantley(Director)inSakae Asanuma(Director)inBriggs Morrison(Executive Officer, Director, Promoter)inIrena Melnikova(Director)in

Board seatTodd Foley· per SEC Form D

Co-investorsLifelinkPfizer Venture InvestmentsBiotechnology Value FundMirae Asset Venture InvestmentPfizer VenturesPolaris Partners+1 more

Frontier Medicinesfrontiermeds.comin𝕏Jun 2021 · $80M

Frontier is a drug discovery company developing small-molecule covalent drugs aimed at previously undruggable protein targets across the proteome.

AI & Machine LearningBiotechSouth San Francisco, US

Chris Varma, Ph.D.(Executive Officer, Director)Chris Varma(Co-founder, Chairman and CEO)inJim Winkler(Executive Officer)Johannes Hermann, Ph.D.(Executive Officer)Kevin Webster(Executive Officer)inGregory Chow(Executive Officer)

Board seatLuke Evnin· per SEC Form D

Co-investorsBerkeley CatalystDCVC (Data Collective)Droia VenturesFelicis VenturesRA CapitalDCVC Bio+2 more

Harpoon Therapeuticsharpoontx.comin𝕏Series B · Nov 2018 · $45M

A research-intensive biopharmaceutical company that develops medicines and vaccines.

BiotechHealthtechSouth San Francisco, US

Luke Nathaniel Walker(Executive Officer)Julie Eastland(Executive Officer, Director)in

BoardRonald Hunt(Director)Mark Chin(Director)Alan Colowick(Director)Jonathan Drachman(Director)

Board seatPatrick BaeuerleLuke EvninPablo CagnoniDan Hicklin· per SEC Form D

Co-investorsK2 HealthVenturesRidgeback CapitalTaiho Ventures, LLCArix BioscienceLilly Asia VenturesNew Leaf Venture Partners+1 more

NextPoint Therapeuticsnextpointtx.comin𝕏Series B · Feb 2024 · $42.5M

NextPoint is a precision therapeutics company developing cancer treatments targeting the B7-H7/HHLA2 axis, including a T-cell engager, an antibody-drug conjugate with proprietary linker technology, and a multi-functional checkpoint inhibitor.

BiotechHealthtechAustin, US

Gordon Freeman(Scientific Founder)XingXing Zang(Scientific Founder)inIvan Cheung(Chief Executive Officer)inLeena Gandhi(Chief Medical Officer)inTatiana Novobrantseva(Chief Scientific Officer)inAxel Hoos(Director)

Board seatDetlev Biniszkiewicz· per SEC Form D

Co-investorsCatalio Capital Management, LPSanofi VenturesCatalio Capital ManagementInvusLeaps by BayerSixty Degree Capital

OncorusinSeries A · Mar 2016 · $57M

Cambridge, US

Christophe Queva(Executive Officer)inTheodore Ashburn(Executive Officer, Director)Alon Lazarus(Director)Cameron Wheeler(Director)in

Board seatMitchell FinerLuke EvninBriggs Morrison· per SEC Form D

Co-investorsAstellas Venture Management LLCCowen Healthcare InvestmentsDeerfield Management CompanyIMM InvestmentK2 HealthVenturesSphera Funds Management

Reunion Neurosciencereunionneuro.comin𝕏Series A · Sep 2025 · $103M

Reunion Neuroscience is a clinical-stage biopharmaceutical company developing serotonergic psychedelic therapies for mental health conditions such as postpartum depression, adjustment disorder, and generalized anxiety disorder.

BiotechDigital HealthMental HealthMorristown, US

Sahil V. Kirpekar(President and CEO)inGregory Mayes(Executive Officer, Director)Ellen Lubman(Director)Mark Pollack(Executive Officer)inNathan Bryson(Executive Officer)inMark Theeuwes(Executive Officer)in

Board seatAnsbert Gadicke· per SEC Form D

Co-investorsFemHealth VenturesMitsui Global InvestmentPalo Santo VCNovo Holdings

Werewolf Therapeuticswerewolftx.cominSeries A · Dec 2020 · $56M

Werewolf Therapeutics is a biotechnology company developing immunotherapy treatments for cancer.

BiotechHealthtechMedical DevicesWatertown, US

Daniel J. Hicklin(Founder, President, Chief Executive Officer, and Board member)Luke Evnin(Co-founder, Board member (Chairman))inDavid Cordo(Executive Officer)Alon Lazarus(Director)

BoardChristoph Westphal(Director)

Board seatLuke EvninBriggs Morrison· per SEC Form D

Co-investorsDC Investment PartnersK2 HealthVenturesLongwood FundRA CapitalTaiho Ventures, LLC

Alestaalestatherapeutics.cominSeries A · Jan 2025 · $67M

Alesta Therapeutics develops therapies for rare diseases, with research focused on genetic diseases and oncology.

BiotechHealthtech

Ilan Ganot(CEO)inBenit Maru(CMO)Matthias Van Woensel(CSO)in

Co-investorsDroia VenturesFrazier Life SciencesNovartis Venture FundRV Invest GmbHFrazier Healthcare PartnersRTW Investments L.P.+1 more

Anokionanokion.comSeries B · Sep 2019 · $40M

Co-investorsVersant VenturesVivo Capital

Antiva Biosciencesantivabio.comin

Antiva Biosciences develops a topical therapeutic for women with high-risk HPV infection and pre-cancerous cervical lesions, utilizing antiviral prodrug chemistry.

BiotechFemTechHealthtechMedical DevicesRedwood City, US

Karl Y. Hostetler(Executive Officer, Director)inGail Maderis(Director)inKristine Ball(President & CEO)inElaine Chien(Executive Officer)inSarah Walter(Executive Officer)inRaju Gadiraju(Executive Officer)in

Co-investorsAdjuvant CapitalAvestria VenturesBrace PharmaCanaan PartnersGV (Google Ventures)HBM Healthcare Investments+6 more

arGEN-Xargenx.com

The company develops therapies for people with severe autoimmune diseases.

BiotechHealthtechMedical Devices

Co-investorsAvoro Capital AdvisorsBioGeneration VenturesHBM Healthcare InvestmentsPMVSeventure PartnersAescap Life Sciences+2 more

AshiBioashibio.comin

āshibio is a biotech company developing novel therapies for rare bone and connective tissue disorders, led by a team of scientists, physicians and drug developers.

BiotechHealthtechBurlingame, US

Pankaj Bhargava(Founder & Chief Executive Officer)inVictoria Smith(Chief Scientific Officer)Deborah Wenkert(Chief Medical Officer)inJoseph Sarret(Acting Chief Operating Officer)Brian Shuster(Acting Chief Business Officer)

Co-investorsAgent Capital

AstronauTX Ltdastronautx.bioin

AstronauTx is a biotechnology company focused on drug discovery and development for neurodegenerative and neuroinflammatory diseases, working across small molecules and biologics.

BiotechDeep TechHealthtechLongevityMedical Devices

Jane Rhodes(Chief Executive Officer)inMagnus Ivarsson(Chief Scientific Officer)inHannah Pearce(Chief Operating Officer)inMichelle L. Mellion(Chief Medical Officer)in

Co-investorsDementia Discovery FundNovartis Venture FundSV Health InvestorsUCL Technology FundAlbionVC

Cullinan Oncologycullinanoncology.comin𝕏

Cullinan Therapeutics develops clinical-stage T cell engager therapies targeting autoimmune diseases and cancer, leveraging immune modulation expertise to advance high-impact therapeutic candidates.

BiotechDigital Health

Co-investorsLAVLilly Asia VenturesSchooner CapitalTaiho Ventures, LLC

Deka Biosciencesdekabiosciences.comSeries B · Sep 2023 · $20M

BiotechGermantown, US

John Mumm(Executive Officer, Director)Vera Mumm(Executive Officer)Pavel Khrimian(Executive Officer, Director)Lucio Iannone(Director)Sally (Yuanheng) Wang(Director)

BoardLu Han(Director)in

Co-investorsATEM Capital FundLumira VenturesPlains VenturesEcho Investment CapitalLeaps by Bayer

elevatebioelevate.bioin𝕏Series A · May 2019 · $150M

ElevateBio is a contract development and manufacturing organization (CDMO) for advanced therapies, offering discovery, process development, analytics, manufacturing, and regulatory support for cell therapies, viral vectors, mRNA therapeutics, and gene editing.

BiotechDeep TechHealthtechWaltham, US

David Hallal(CEO)inMike Paglia(Chief Technology Officer)Ger Brophy(CEO)in

Co-investorsEcoR1 CapitalSamsara BioCapitalSoftBank Vision Fund

Epi Biologicsepibiologics.cominSeries B · Jan 2026 · $110M

Epibiologics develops protein degradation medicines using protein sciences and antibody engineering capabilities.

BiotechMedical DevicesSan Mateo, US

Ann Lee-Karlon(Executive Officer, Director)inMitchell Mutz(Executive Officer, Director)James Wells(Director)

BoardSamuel Bjork(Director)inAlexandra Cantley(Director)inSeiji Miyahara(Director)in

Co-investorsAvego BioScience CapitalGV (Google Ventures)Mission BiocapitalNovartis Venture FundRoche Venture FundSamsara BioCapital+4 more

Fireflyfireflybiologics.comin

Firefly Bio develops antibody-drug conjugates (ADCs) that use novel classes of payloads, drawing on a research team experienced in ADC discovery and development.

BiotechHealthtechMedical Devices

Scott Hirsch(CEO)inDan Kaplan(CSO)

Co-investorsDecheng Capital

ForteBiofortebio.comSep 2008 · $25Macquired by Pall

Developed biotech research instruments for measuring molecular binding; acquired by Pall Corporation for $159M.

Co-investorsLatterell Venture PartnersOrbiMedThe Vertical GroupVersant Ventures

Immunitas Therapeuticsimmunitastx.cominSeries A · Nov 2019 · $39M

Immunitas discovers and develops therapeutic antibodies for cancer and autoimmune diseases, with its lead program targeting CD161 for solid tumors and hematological malignancies.

BiotechDigital HealthMedical DevicesWaltham, US

Amanda Wagner(Executive Officer)Dan Matloff(Executive Officer)Jiaping Gu(Director)Jeffrey Goldberg(Executive Officer, Director)

BoardLaura Brass(Director)inKai Wucherpfennig(Director)

Co-investorsAgent CapitalDC Investment PartnersLifelinkLongwood FundMedical Excellence CapitalNovartis Venture Fund+5 more

K2k2tx.com

K2 Therapeutics is a biotech company that identifies innovative drug assets and develops them into medicines using a hub-and-spoke model with cross-regional clinical trials.

BiotechHealthtech

Co-investorsAlpine Space VenturesAltimeter CapitalCapitalGICONIQKleiner PerkinsLightspeed Venture Partners+4 more

K2 Spacek2space.ioin𝕏Aug 2026 · $50M

The page is an online gambling/betting operator ("OK9") targeting Vietnamese players, offering sports betting, online casino, slots, fish-shooting games, lottery, and card games.

Deep TechHardwareSpace TechWest Hollywood, US

Neeldev Kunjur(Executive Officer, Director)Karandev Kunjur(Executive Officer, Director)Karan Kunjur(Founder)inNeel Kunjur(Founder)in

Co-investorsAlpine Space VenturesAlso CapitalAsymmetric Capital PartnersCapitalGEarthrise VenturesFirst Round Capital+21 more

Ornaornatx.cominSeed · Jan 2020 · $20M

Orna Therapeutics develops RNA and lipid nanoparticle (LNP) based therapies for treating diseases including oncology and cell therapy applications.

AI & Machine LearningBiotechMedical Devices

Joe Bolen(Chief Executive Officer)Joe Bolen, Ph.D.(Chief Executive Officer)Hope D'Oyley-Gay, JD(Chief Legal Officer)Ciaran Lawlor, Ph.D.(Chief Operating Officer)Frank Neumann, M.D., Ph.D.(Chief Medical Officer)Siva Sakhamuri(Chief Technology Officer)in

Co-investorsAstellas Venture Management LLCTaiho Ventures, LLC

Protego Biopharmaprotegobio.cominDec 2025 · $130M

Protego Bio is a biotech company developing first-in-class therapies for protein misfolding diseases, including its lead candidate PROT-001 for AL amyloidosis, based on research into pharmacological chaperones.

AI & Machine LearningBiotechDeep TechDigital HealthHealthtechSan Diego, US

Brent J. Warner(Executive Officer, Director)inXIN JIANG(President & CEO)inHANK MICHAEL PETRASSI(Executive Officer)JEFFERY KELLY(Director)

BoardTIM LOHOFF(Director)Edward Hurwitz(Director)

Co-investorsDroia VenturesNovartis Venture FundDigitalis VenturesForbionLightspeed Venture PartnersVida Ventures+1 more

ReCode Therapeuticsrecodetx.comin𝕏

ReCode develops mRNA and gene correction therapeutics for genetic diseases, using proprietary lipid nanoparticle technology to deliver treatments to specific organs.

AI & Machine LearningBiotechHealthtechMedical DevicesMenlo Park, US

Dr. Daniel J. SiegwartArthur E Johnson(Executive Officer, Director)

Co-investorsAju IB InvestmentEcoR1 CapitalEvolution VC PartnersOrbiMedOUP (Osage University Partners)Pfizer Venture Investments+6 more

Selexys Pharmaceuticalsin

BiotechOklahoma City, US

Scott Rollins, Ph.D.(Executive Officer, Director)David Falconer(Executive Officer)inRichard Alvarez(Executive Officer)inRussell Rother(Executive Officer)inRodger McEver, M.D.(Director)

BoardPhilip Jones, M.D.(Director)

Semma Therapeuticssemma-tx.comNov 2017 · $114Macquired by Vertex Pharmaceuticals · Sep 2019 · $950M

Cambridge, MA biotech developing stem cell-derived islet therapy plus an immune-protective device for type 1 diabetes; acquired by Vertex for $950M.

BiotechCambridge, US

Robert Millman(Executive Officer, Director)

BoardTodd Foley(Executive Officer, Director)inMitch Finer(Director)Stephen Knight(Director)inJim Scopa(Director)William Sahlman(Director)

Co-investorsARCH Venture PartnersF-Prime CapitalJDRF T1D FundORI CapitalSlater Technology Fund6 Dimensions Capital+4 more

SiO2 Medical Productssio2ms.comNov 2019

SiO2 Materials Science develops precision molded polymer containers with thin glass-like barrier coatings for pharmaceutical and biopharmaceutical applications.

BiotechMedical DevicesNew MaterialsAuburn, US

Robert S. Abrams(Executive Officer, Director)inRobert Pangborn(Director)John Belfance(Director)Jean-Marie Painvin(Director)Thomas Strungmann(Director)Jared Morris(Director)

Valeritasvaleritas.cominJun 2014

An Italian-language affiliate guide that reviews and ranks non-AAMS online casinos (foreign-licensed gambling sites) accessible to Italian players, comparing bonuses, game catalogs, payment methods, and licensing.

ConsumerGamingMedia & EntertainmentBridgewater, US

William Duke(Executive Officer)inKristine Peterson(Executive Officer, Director)

BoardDaniel Pelak(Director)Sean Traynor(Director)Ittai Harel(Director)inPaul Queally(Director)

Co-investorsAgate Medical Investments LPHLM Investment PartnersKaiser Permanente VenturesAbingworthPitangoWelsh, Carson, Anderson & Stowe

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

Amphivena TherapeuticsBioInterveneBlade TherapeuticsFirefly Bio, Inc.HotKnot Therapeutics, Inc.Maverick TherapeuticsMoat BiotechnologyPotenza TherapeuticsRedona Therapeutics, Inc.Rekindle TherapeuticsTetherex Pharmaceuticals CorpTrieza TherapeuticsVesuvius PharmaceuticalsāshibioCoDa TherapeuticsIconic TherapeuticsIdun PharmaceuticalsiTeos TherapeuticsK2 TherapeuticsNeoVistaProtegoRadius HealthReNAgade TherapeuticsReunionTCR2

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

Exits · 6

4 IPOs · 2 acquisitions

Aktis OncologyNASDAQ: AKTSEntrada Therapeutics, Inc.NASDAQ: TRDADyne TherapeuticsNASDAQ: DYNSyndax PharmaceuticalsNASDAQ: SNDXForteBioacq. by PallSemma Therapeuticsacq. by Vertex Pharmaceuticals

Portfolio news

latest coverage across their companies

IPO stake values · per SEC filings · 3

Value of this firm's stake in each portfolio company at its IPO price, from the prospectus principal-stockholder table.

CompanyOwnedIPO priceAt IPOStake value
Aktis Oncology17.4%$18.00Jan 2026$164.7M
Entrada Therapeutics, Inc.14.4%$20.00Nov 2021$86.5M
Syndax Pharmaceuticals12.5%$12.00Mar 2016$26M

Source: SEC S-1 / 424B prospectus filings. Stake value = shares beneficially owned × the initial public offering price, as disclosed — a market value at IPO, not a return multiple (the firm's original cost is not disclosed).

Frequently asked questions

How many investments has MPM BioImpact made?
MPM BioImpact has 67 tracked investments, 6 of which have exited, including 8 dated in the last 24 months.
What stage does MPM BioImpact invest at?
MPM BioImpact invests at the Pre-Seed, Seed, Series A, Series B, Series C, Growth, Late Stage stages.
What is MPM BioImpact's typical check size?
MPM BioImpact typically writes checks of $1M – $15M.
What sectors does MPM BioImpact focus on?
MPM BioImpact focuses on Biotech, Healthtech, Impact & Social Good, Longevity, Mental Health.
Where is MPM BioImpact located?
MPM BioImpact is headquartered in Boston, US.
Does MPM BioImpact lead rounds?
MPM BioImpact has led 5 of the 14 rounds where its role is on record.
Who does MPM BioImpact co-invest with?
MPM BioImpact most often shares deals with Vida Ventures, Astellas Venture Management LLC, Canaan Partners, among 61 tracked co-investors.

Co-investors · 39

Novartis Venture Fund

The Novartis Venture Fund invests in innovative life science companies, primarily in biotechnology and biopharmaceuticals, at various stages of development across North America and Europe.

$5M – $25M
RA Capital

RA Capital Management is a healthcare and planetary health investment firm that founds, funds, and scales companies using scientific diligence, multi-stage capital, and hands-on operational support.

Versant Ventures

Versant Ventures operates in-house Discovery Engines staffed by multidisciplinary scientists in dedicated laboratory facilities to help launch new biotechnology companies alongside academic founders.

$250K – $5M
OUP (Osage University Partners)

OUP (Osage University Partners) is a venture firm that invests in science-driven startups commercializing deep technology innovations emerging from university and breakthrough research.

$1M – $20M
OrbiMed

OrbiMed is a healthcare-focused investment firm providing tailored financing solutions and global resources to build world-class healthcare companies across biopharmaceuticals, medical devices, digital health, diagnostics, and healthcare services.

$1M – $75M
Deerfield Management Company

Deerfield Management is a healthcare-focused investment firm that supports companies across the healthcare ecosystem through flexible funding, market intelligence, and philanthropic initiatives.

Abingworth

Abingworth is a life science venture capital firm that backs early-stage biopharma and biotech companies, helping entrepreneurs translate scientific discoveries into new therapeutics.

$15M – $30M
Pfizer Venture Investments

Pfizer Venture Investments is a strategic venture fund that doesn't require product or technology rights as a condition of investing, giving founders independence while still aiming for future collaboration with Pfizer, and its team blends venture investing with business development and drug discovery expertise to back frontier scientific bets—such as neuroscience, in-vivo cell engineering, dark-genome target discovery, and the blockchain-based longevity accelerator VitaDAO—that many biotech investors avoid. The fund also runs an active China strategy through a locally based venture vehicle and direct investments like OTR Therapeutics, and it has become a channel for strategic deals, with portfolio companies acquired by AbbVie, Ipsen, and Gilead/Kite.

$5M – $20M
Longwood Fund

Longwood Fund is a venture capital firm that creates and invests in novel healthcare companies developing new treatments for patients, drawing on its partners' company-building and operating experience.

Agent Capital

Agent Capital is a healthcare venture capital firm that makes direct equity investments in novel, differentiated therapeutics and treatments addressing unmet patient needs, from preclinical through commercial stages.

MRL Ventures Fund

MRL Ventures Fund (MRLV) is the therapeutics-focused corporate venture group of MSD (Merck & Co.), investing globally in early-stage, preclinical therapeutics companies and providing capital, board partnership and access to MSD's R&D domain expertise.

$25M
▶27 more co-investors

GV (Google Ventures)Kleiner PerkinsPolaris PartnersARCH Venture PartnersDigitalis VenturesVivo Capital6 Dimensions CapitalAndreessen Horowitz8VCAtlas VentureFrazier Healthcare PartnersQiming Venture PartnersMedical Excellence CapitalNovo HoldingsCatalio Capital Management, LPBessemer Venture PartnersNorwest Venture PartnersDraper Fisher Jurvetson (DFJ)Third Point VenturesEarlybird Venture CapitalSofinnova PartnersSR One Capital ManagementThe Column GroupTencent HoldingsCofounders CapitalPureos BioventuresJMI Equity

Firms observed investing alongside MPM BioImpact, from public investor directories. Shared companies are the overlap with MPM BioImpact's recorded portfolio.

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