San Francisco · Pre-Seed–Seed · 18 people tracked
Also known as Fifty Years Deep · FIFTY YEARS INDUSTRIES, LLC
Find your way into Fifty Years
2,448 people in our graph share verified history with the Fifty Years team — schools, employers, funds. One of them is your warm intro.
Investment thesis
Fifty Years invests at the pre-seed and seed stages in founders who apply breakthrough science and technology to address humanity's biggest challenges, including climate change, disease, connectivity, and malnutrition. The firm has a strong emphasis on deep tech and scientist-founders, having backed dozens of PhD founders and CEOs, and positions itself as helping world-class scientists become world-class entrepreneurs. Beyond capital, 50Y helps start companies and is backed by a network of founders of billion-dollar technology companies who support the next generation. Its guiding philosophy is to use capitalism as a force for good.
Source: firm website, verified Sep 15, 2026.
Team · 18 people
from the firm's website & curated & public directories
Founder mafia
The Fifty Years mafia →7 people who came through Fifty Years went on to found or lead other companies.
What they invest in
from 144 of 165 portfolio companiesBiotech ×76Deep Tech ×64AI & Machine Learning ×60Healthtech ×40Medical Devices ×19Advanced Manufacturing ×18Climate Tech ×18Digital Health ×16
HQs:United States×75United Kingdom×5Canada×4Germany×2Australia×1Spain×1
Who they back
founder profiles across 109 portfolio companiesFounding team size:solo founder×362 founders×443 founders×174+ founders×12
Where their founders studiedfrom 148 founders with education data
Massachusetts Institute of Technology ×15University of California, Berkeley ×14Harvard University ×8University of Cambridge ×7Stanford University ×5University of Colorado Boulder ×5Technical University of Munich ×4Cornell ×3
What their founders studiedfrom 152 founders with field-of-study data
Engineering ×51Life Sciences ×39Computer Science ×27Business & Management ×13Mathematics & Statistics ×10Chemistry ×9Economics ×6Physics ×6
Where their founders worked beforefrom 156 founders with career history
Stanford University ×21Caltech ×7Harvard Medical School ×5Harvard University ×4Massachusetts Institute of Technology ×4Tesla ×4Freenome ×3Joint BioEnergy Institute ×3
Accelerator rootsportfolio companies that came through a program
81 founders hold a PhD · 4 hold an MBA (of 161 with degree data)
Investments · 165 tracked
founders shown can be your intro pathBy year:2026 · 42025 · 62024 · 42023 · 52022 · 82021 · 72020 · 22019 · 22017 · 139 dated
BillionToOne is a precision diagnostics company that uses molecular counting technology to develop non-invasive prenatal screening and liquid biopsy tests for early disease detection.
BiotechDigital HealthHealthtechMedical DevicesSan Francisco, US
Oguzhan Atay, PhD(Co-Founder, CEO, and Board Chair)inDavid Tsao, PhD(Co-Founder, CTO, and Board Member)Oguzhan Atay(Founder)inDavid Tsao(Founder/CTO)inSukrit Silas(Cofounder)in
Co-investors500 Emerging Europe500 GlobalAsymmetry VenturesCivilization Ventures Management, Llce2vcFriale+15 more
Health Catalyst provides a data platform, analytics applications, and AI-powered insights that help healthcare organizations improve clinical, financial, and operational performance.
AI & Machine LearningData & InfrastructureDigital Health
Benjamin Albert(Chief Executive Officer and Director)Jason Alger(Chief Financial Officer)inLinda Llewelyn(Chief People Officer)in
Co-investorsDecheng CapitalEPIC VENTURESKaiser Permanente VenturesNorwest Venture PartnersOSF VenturesTenaya Capital+2 more
Pediatrix provides physician-led specialized medical care for women, babies, and children, delivered both in person and virtually across the United States.
Digital HealthHealthtechSunrise, US
Roger J. Medel, M.D.(Executive Officer, Director)Joseph M. Calabro(Executive Officer)Vivian Lopez-Blanco(Executive Officer)Dominic Andreano(Executive Officer)Mark S. Ordan(Chief Executive Officer and Chair of the Board)Kasandra H. Rossi(Executive Vice President, Chief Financial Officer and Treasurer)
Co-investorsCity LightCollaborative FundGaingelsGreycroftY Combinator
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Solugen develops a biomanufacturing platform using fermentation and bioprocessing technology to produce specialty chemicals at scale.
Advanced ManufacturingBiotechCleantechClimate TechHealthtechHouston, US
Sean Hunt(Founder/CTO)inGaurab Chakrabarti(Founder)in
Board seatSeth Bannon· per SEC Form D
Co-investorsFounders FundLowercarbon CapitalY CombinatorBaillie GiffordGICKdT Ventures+22 more
Wafer develops performance optimization tools and services across GPU accelerators, architectures, and computing stack layers.
AI & Machine LearningCloud ComputingDeep TechDeveloper ToolsEnterprise SoftwareSan Francisco, US
Emilio Andere(Founder)inSteven Arellano(Founder)in
Co-investorsY CombinatorWing
54Gene conducts genomics research and provides related services to increase the representation of African genetic data in medical research, which aims to advance healthcare solutions globally.
HealthtechWellness & FitnessLagos, NG
Gatumi Aliyu(Founder)inAbasi Ene-Obong(Founder)inOgochukwu Francis Osifo(Founder)in
Co-investorsAdjuvant CapitalEndeavor CatalystThe Raba PartnershipV8 Capital PartnersY Combinator
64x provides a platform and product suite for manufacturing advanced therapeutics, including gene therapies, cell therapies, and biologics.
BiotechDeep TechMedical Devices
Co-investorsBoxGroupFirst Round CapitalFuture VenturesLifeforce CapitalNorthpond VenturesRefactor Capital+1 more
64x develops infrastructure and manufacturing systems for next-generation medicines, focusing on genetic engineering, cell line development, and computational biology to enable scalability of advanced therapies.
AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesSan Francisco, US
Lexi Rovner(Co-founder & CEO)in
Co-investorsFuture VenturesLifeforce CapitalRaptor GroupY CombinatorAlix VenturesBoxGroup+4 more
Aalo develops advanced nuclear reactor technology aimed at producing electricity at under 3 cents per kilowatt-hour.
Climate TechDeep TechEnergyHardware
Matt(Co-founder)inYasir(Co-founder)in
Co-investorsAlumni VenturesBanca Investis — Family OfficeBasecamp FundBlack FlagBrave CapitalCrosscut Ventures+26 more
AcouBatt provides acoustic monitoring and AI-based detection for battery energy storage systems, identifying abnormal cell behavior and safety risks in real time.
Advanced ManufacturingAI & Machine LearningDeep TechEnergyHardwareIoTLondon, GB
Dr. Arthur Fordham(Co-founder)
Co-investorsCreator Fund
Acre is a Bitcoin-focused DeFi protocol offering auto-compounding vaults that let BTC holders earn yield through curated onchain strategies while retaining self-custody of their private keys.
Crypto & Web3Fintech
Co-investorsDraper DragonFlowdeskSilvermine CapitalCollaborative FundFootPrint CoalitionLowercarbon Capital+1 more
Adaption Labs builds adaptive AI systems that continually learn and adjust to specific industries, languages, and use cases, positioning itself against large monolithic, one-size-fits-all models.
AI & Machine LearningDeep Tech
Co-investorsAlpha Intelligence CapitalEmergence Capital PartnersMozilla VenturesThe E14 FundThreshold VenturesZ21 Ventures
Advano manufactures silicon-based anode materials for lithium-ion batteries that improve energy density and reduce costs for electric vehicles.
Advanced ManufacturingCleantechClimate TechNew Orleans, US
Shiva Adireddy(Founder/CTO)inAlexander Girau(Founder)in
Co-investorsAAF Management Ltd.Boot64 VenturesGlobivestInnovation CatalystNew Orleans Startup FundPartech Ventures+3 more
Alpine Bio develops and commercializes functional proteins and bioactive ingredients for food, nutrition, and health applications, targeting formulators who need performance, supply reliability, and clean-label positioning.
AgTechBiotechFoodTechNew Materials
Co-investorsBreakthrough Energy VenturesGermin8 Ventures
Ansa provides an enzymatic DNA synthesis platform that directly synthesizes complex sequences up to 900 bp and delivers constructs up to 50 kb without assembly-based methods.
BiotechDeep TechHealthtechEmeryville, US
Dan Lin-Arlow(Founder)inSebastian Palluk(Founder)inDaniel Lin-Arlow(Executive Officer, Director)inDaniel Hillel Lin-Arlow(Executive Officer, Director)Jason T. Gammack(Executive Officer, Director)in
BoardYanniv Dorone(Director)
Co-investorsCarbon SiliconCerberus VenturesDauntless VenturesMetaplanetY CombinatorFall Line Capital+3 more
Antora manufactures thermal battery systems for long-duration energy storage, serving manufacturers and data centers seeking to tap into low-cost renewable power.
CleantechEnergyEnterprise SoftwareHardwareSunnyvale, US
Andrew Ponec(Chief Executive Officer, co-founder)inDavid BiermaninJustin BriggsinDavid Bierman, Ph.D.(Chief Commercial Officer, co-founder)Justin Briggs, Ph.D.(Chief Operating Officer, co-founder)
BoardChristina Karapataki(Director)in
Co-investorsTemasekCongruent VenturesCreative Destruction Lab (CDL)GS FuturesISVLoup Ventures+14 more
Antora Energy builds factory-made thermal batteries that store intermittent low-cost electricity as heat in carbon blocks and deliver around-the-clock heat and power at scales from megawatts to gigawatts.
CleantechClimate TechEnergySan Jose, US
Andrew Ponec(Founder)in
Co-investorsBlackRockTemasekBreakthrough Energy VenturesISV
Apollo Atomics develops compact nuclear power systems designed for rapid deployment.
Advanced ManufacturingClimate TechDeep TechEnergyBoston, US
Assil Halimi(Founder)inDrew Walker(Co-Founder/COO)in
Co-investorsKima VenturesOrange CollectivePerceptive Ventures Management Company, LlcScribble VenturesTranspose Platform ManagementValia Ventures+1 more
Aralez Bio produces noncanonical amino acids using biocatalysis, including compounds that add rigidity to peptide backbones and increase enzyme resistance.
BiotechCleantechClimate TechDeep TechNew MaterialsBerkeley, US
Tina Boville(Co-founder & CEO)inDavid Romney(Co-founder)inFrances Arnold(Co-founder / Scientific Founder)
Co-investorsAstiaFREEFLOWGood Growth CapitalISVJuniperPaladin Capital Group+1 more
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Arpeggio Bio develops pharmaceutical drugs that target transcription factors using artificial intelligence and RNA-sequencing technology, with lead programs in development for melanoma treatment and rare disease applications.
BiotechHealthtechBoulder, US
Joey Azofeifa(Founder)inLaura Norris(Executive Officer, Director)inTimothy Read(Executive Officer, Director)Eric Martin(Executive Officer)in
BoardAmit Mehta(Director)
Co-investorsFundersClubTau VenturesvenBio PartnersY CombinatorAlamo AngelsBoxOne Ventures+3 more
AssureDrop develops droplet microfluidics-based screening technology that works within standard multiwell plates for pipette-free, high-throughput screening of 3D cell models such as spheroids.
BiotechDeep TechHealthtech
Ankur Chaurasia(Founder)in
Astranis manufactures small, high-powered geosynchronous satellites equipped with advanced digital processing technology for global telecommunications and connectivity services.
Advanced ManufacturingDeep TechHardwareSpace TechSan Francisco, US
John Gedmark(Founder/CEO)inRyan McLinko(Founder/CTO)in
Co-investorsAndreessen HorowitzBlack FlagBoxGroupCantos VenturesCherubic VenturesCommonweal Ventures+39 more
Athelas develops software tools for private practice healthcare providers to reduce administrative burden, improve operational efficiency, and enhance patient scheduling and navigation capabilities.
AI & Machine LearningEnterprise SoftwareHealthtechSaaSSan Francisco, US
Deepika Bodapati(Founder)inTanay Tandon(Founder)in
BoardHemant Taneja(Director)in
Co-investorsAmity VenturesDorm RoomGeneral CatalystHuman CapitalLiquid VenturesY Combinator+5 more
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Atom Computing develops large-scale quantum computers using optically-trapped neutral atoms for on-premises deployment.
Deep TechHardwareQuantum ComputingBerkeley, US
Ben Bloom(Founder & CEO)in
BoardDror Berman(Director)inEthan Batraski(Director)in
Co-investorsAbstract VenturesAlumni VenturesBerkeley FrontierBlue Ivy VenturesBoxGroupCantos Ventures+18 more
Avro Life Sciences develops platform technology for novel drug delivery through passive transdermal administration.
BiotechHealthtechMedical DevicesWaterloo, CA
Shak Lakhani(Founder)inKeean Sarani(Founder)in
Co-investorsCreative Destruction Lab (CDL)Garage CapitalHeuristic Capital PartnersUpHonest CapitalWaterloo Accelerator CentreY Combinator+1 more
Azulene Labs develops physics-powered molecular discovery technology.
AI & Machine LearningBiotechDeep TechNew MaterialsBerkeley, US
Co-investorsEntrada Ventures
Bioqore builds Voyager, an AI-powered closed-loop bioprocess intelligence platform that combines predictive modeling with micro-scale laboratory experiments to recommend and validate optimal process conditions for producing preclinical- and clinic-ready therapeutic candidates.
AI & Machine LearningBiotechDeep Tech
Joshua Hinckley(CEO)inBrendan Dang(COO)in
Co-investorsAdverb VenturesMaC Venture Capital
BioRender is a software tool that enables scientists to create and share professional scientific illustrations and figures.
BiotechEdTechEnterprise SoftwareSaaSToronto, CA
Ryan Marien(Founder)inKatya Shteyn(Founder)inShiz Aoki(CEO and Co-founder)in
Co-investorsY CombinatorFundersClubStandard CapitalRefactor CapitalZeno Ventures
BIOS develops neural digital therapy technology to deliver treatments for neurological conditions.
AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesCambridge, GB
Oliver Armitage(Founder)inEmil Hewage(Founder/Director)in
Co-investorsHeuristic Capital PartnersKern Venture GroupThe Venture CollectiveY CombinatorSelvedge Venture
BloomText provides HIPAA-compliant messaging software built specifically for healthcare organizations.
Digital HealthHealthtechSaaSSeattle, US
Michael Wasser(Founder/CEO)inHeather Milone(Founder/Executive Business Advisor)in
Co-investorsY CombinatorSection 32Slow Ventures
Boltz develops generative AI models for biomolecular design and drug discovery, used by researchers across pharmaceutical, biotech, agricultural, and academic sectors.
AI & Machine LearningBiotechDeep TechLondon, GB
Gabriele Corso(Founder)inSaro Passaro(Founder)in
Co-investorsAmplify PartnersAndreessen HorowitzAmplify Partners CVFactorial CapitalObvious VenturesZetta Venture Partners
Brave Care operates pediatric primary and urgent care clinics designed to treat common acute conditions in children, supplemented by remote consultations delivered by clinicians.
HealthtechPortland, US
Asa Miller(Founder)inDarius "Bubs" Monsef(Founder)inMaryam Taheri(Founder)inCorey Fish, MD(Founder)inGary Gerlacher(Executive Officer, Director)Corey Fish, M.D.(Executive Officer, Director)
Co-investorsAV8 VenturesVentureSouqY CombinatorZillionizeCity LightCollaborative Fund+4 more
Cache develops a platform for reliable long-term storage and access of biomolecules to support precision medicine and fundamental research.
BiotechDeep TechHealthtech
Co-investorsHAWKTAILJuniperLifeX VenturesTrousdale VenturesValkyrie
Biomemory develops DNA-based data storage systems for data centers, offering an alternative storage tier optimized for long-term archival, density, and energy efficiency.
Climate TechData & InfrastructureDeep Tech
Hyunjun Park(CEO)
Co-investorsCivilization Ventures Management, LlcHemisphere Ventures LLCNew Enterprise Associates (NEA)Prefix CapitalZ Venture CapitalCantos Ventures+3 more
A biotech company associated with immunology and cellular research, listing medical and scientific advisors.
Biotech
Mark Davis(Founder and scientific advisor)Kate Medetgul-Ernar(Founder and COO)Kwat Medetgul-Ernar(Founder and CEO)Pablo Tamayo, PhD(Founder and scientific advisor)
Co-investorsHumba Ventures
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Clippership designs and builds autonomous wind-powered vessels with wing-sails to move cargo across water using wind instead of fuel.
CleantechLogistics & Supply ChainRoboticsRedwood City, US
Kai Matsuka(CTO)inNiccolo Cymbalist(Founder)inNico Cymbalist(CEO)Luca Cymbalist(COO)
Co-investorsBlack FlagFounders Factory
Cofactor Genomics develops predictive diagnostics for cancer immunotherapy using RNA-expression models to characterize tumor microenvironments and predict patient response.
AI & Machine LearningBiotechHealthtechMedical DevicesSt. Louis, US
Dave Messina(Founder/COO)inJarret Glasscock(Founder/CTO)inJarret Glassock(Executive Officer, Director)Jon Armstrong(Director)in
BoardMatthew A. Ocko(Director)inMark Siegel(Director)in
Co-investorsArgonautic VenturesAscension VenturesDCVC (Data Collective)iSelect FundMenlo VenturesY Combinator+1 more
Ultra efficient all-electric passenger aircraft with real range capabilities
Marshall Gusman(Co-founder & CTO)inChristopher Chahine, PhD(Co-founder & CEO)
Co-investorsAera VCCourse Corrected VC Holding IISamurai IncubateSyndicate OnePale Blue DotPossible Ventures
Cover designs and builds modular homes using technological and material innovations to reduce construction waste and improve energy efficiency.
Climate TechConstruction TechPropTechGardena, Los Angeles, US
Alexis Xavier Rivas(Founder)in
Co-investorsEarl Grey CapitalGigafundGreat Oaks Venture CapitalManta Ray VenturesPartners Resolute
Deepcell uses artificial intelligence and high-resolution imaging to analyze cell morphology for biological research and discovery.
AI & Machine LearningBiotechDeep TechMedical DevicesSunnyvale, US
Mahdokht Masaeli(Executive Officer, Director, Promoter)Mahyar Salek(Executive Officer, Director, Promoter)inMaddison Masaeli(Founder)inEuan Ashley(Director, Promoter)
Co-investorsAndreessen HorowitzBow CapitalDCVC (Data Collective)Horizons VenturesLifeX VenturesManta Ray Ventures
Digital Biology (Digit Bio) develops precision biologics and combination therapies for solid tumors, using its M×P (Molecules × Phenotypes) Platform that combines high-resolution imaging, next-generation sequencing, computation, and AI to map the spatial molecular organization of tumor tissues.
AI & Machine LearningBiotechDeep TechHealthtech
Co-investorsA91 PartnersGoldman SachsHSBCMorgan StanleySteadview Capital
Dipole Labs develops photonic (optical) hardware intended to serve as the optical layer for AI and quantum computing infrastructure, aiming to overcome the physical limits of silicon in speed, density, and efficiency.
Advanced ManufacturingAI & Machine LearningDeep TechHardwareQuantum ComputingBoston, US
Gabriele Pasquale(Co-founder & CTO)inDeepankur Thureja(Co-founder & CEO)in
Co-investorsY CombinatorCisco InvestmentsTranspose Platform Management
Earth AI uses AI to locate critical mineral deposits by analyzing geological data, supporting the supply chain for hardware and emerging technologies.
Advanced ManufacturingAI & Machine LearningClimate TechDeep TechNew MaterialsSan Francisco, US
Roman Teslyuk(Founder)in
BoardIan Rountree(Director)inMikhail Taver(Director)inJamie Lee(Director)inIsabella Sykes(Director)Arnoud Balhuizen(Director)
Co-investorsAirTree VenturesAlpaca VCBlackbird VenturesCantos VenturesCorigin VenturesDCVC (Data Collective)+13 more
eFlow extracts lithium from dilute brines in North America using direct lithium extraction technology, serving the clean energy and electric vehicle supply chain.
CleantechEnergyNew MaterialsSan Bruno, US
Eric McShane(CEO and co-founder)Evan Gardner(CTO and co-founder)in
Co-investorsBlack FlagHarpoon VenturesUnion Square Ventures (USV)Voyager Partners
Elicit is an AI-powered research assistant that helps users discover, analyze, and synthesize scientific literature and research findings.
AI & Machine LearningEdTechEnterprise SoftwareSaaSOakland, US
Andreas Stuhlmüller(Cofounder & CEO)inJungwon Byun(Cofounder & COO)inAdam Heneghan(Executive Officer)in
BoardKevin Willer(Director)John Elton(Director)John McGee(Director)
Co-investorsFootworkMythos Ventures Management, LlcPreston-Werner VenturesWinklevoss CapitalBasis Set Ventures
Enoda develops synthetic cytokine receptors, called MIMICs, that link therapeutic "Signal 3" cytokine functions to controllable inputs to engineer cell therapies without systemic toxicity.
BiotechDeep TechLondon
Andrew John Scobie(Executive Officer, Director)Michael Chavez(Co-founder & CEO)inPaul B. Finn(Founder)inJennifer Urquhart(Executive Officer, Director)inJacqueline Elizabeth Porch(Executive Officer, Director)Lindsay James Whitelaw(Executive Officer, Director)
Co-investorsMBX Capital
Ethic offers direct indexing and tax-smart portfolio management, providing customizable passive portfolios engineered for tax efficiency, factor exposures, and values alignment.
FintechImpact & Social GoodPropTechSaaSNew York, US
Doug Scott(CEO & Co-founder)inJay Lipman(Founder)inJohny Mair(Founder)inJohn Mair(Director)inJordan Lipman(Director)
BoardJohn Morris(Director)
Co-investors500 GlobalBetter Tomorrow VenturesBlackhorn VenturesFarvatn VentureKima VenturesNyca+6 more
Externa develops biologics using genetic code expansion, a technology aimed at incorporating synthetic amino acids into proteins of any type and size.
BiotechDeep Tech
Faction develops a hybrid autonomous vehicle platform called DriveLink that combines autonomy with remote human assistance (TeleAssist) for driverless fleet operations.
Advanced ManufacturingAI & Machine LearningLogistics & Supply ChainMobility & TransportationRoboticsSan Francisco, US
Ain McKendrick(Founder)in
Co-investorsKube VCY CombinatorFactionLightspeed FactionTDK Ventures
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Farcast develops advanced satellite communication user terminals with flat panel phased array antennas that electronically track satellite movement for reduced size, weight, power, and cost.
Advanced ManufacturingHardwareSpace TechSan Francisco, US
Siamak Ebadi(Founder)in
BoardDavid Byrd(Director)inGuido Jouret(Director)
Co-investorsBlueYard CapitalGarage CapitalMaC Venture CapitalY CombinatorLockheed Martin VenturesMango Capital+1 more
IGOR is a multi-agent AI platform, or "AI co-scientist," designed to accelerate R&D and experimental discovery by closing the loop between hypothesis and empirical validation.
AI & Machine LearningBiotechDeep Tech
Dr. Scott C. Riggs(Founder)in
Float builds large rigid-frame autonomous airships as an industrial freight platform, using modern materials, sensing, autonomy, and meteorology for lighter-than-air cargo logistics.
Deep TechLogistics & Supply ChainRoboticsSan Francisco, US
Conor Lenahan(Founder & CEO)inJames Harvey(CTO)in
Garten provides healthy food, meditation, mindfulness and community wellness services for workplace environments.
AI & Machine LearningEnterprise SoftwareFoodTechFuture of WorkWellness & FitnessSan Francisco, US
Michael Heinrich(Founder/CEO)in
Co-investorsBackedBY Venture PartnersFundersClubMontage CapitalY CombinatorACE & Company+1 more
Geltor uses a proprietary biodesign and precision fermentation platform to create and commercially produce novel protein ingredients, including collagens, for beauty and personal care formulators.
BiotechFoodTechNew MaterialsWellness & Fitness
Alexander Lorestani(Founder)inNick Ouzounov(Co-founder)in
Co-investorsAgronomicsAlwyn CapitalArgonautic VenturesBaruch Future VenturesBlue Horizon CorporationCavallo Ventures+14 more
Gordian Biotechnology develops therapies aimed at treating age-related diseases to extend healthy lifespan.
AI & Machine LearningBiotechHealthtechLongevity
Co-investorsage1MetaplanetPrime Movers LabStreamlined VenturesW ventures10x Founders
Gridware provides real-time monitoring and visibility of electrical grid conditions through sensors deployed on power lines, enabling utilities and line workers to detect and respond to problems faster.
Advanced ManufacturingClimate TechEnergyEnterprise SoftwareHardwareIoTSan Francisco, US
Tim Barat(Founder)inOmar B(Founder)inHall Chen(Co-Founder & CTO)in
Co-investorsAiSprouts VCAnorak VenturesConvective CapitalHAWKTAILLOWERCARBONLowercarbon Capital+7 more
HarborSite develops a targeted gene insertion platform that engineers site-specific recombinase enzymes to integrate therapeutic genes into safe genomic sites.
BiotechDeep TechLongevity
Erik Aznauryan, PhD(Founder)in
Co-investorsSciFoundersSmartGateVC
Harmonic Discovery applies medicinal chemistry, cheminformatics, data science and machine learning expertise to advance drug discovery.
AI & Machine LearningBiotechDeep TechHealthtechNew York City, US
Rayees Rahman(Founder CEO)inJ Lee(Founder)inMarcel Patek(Founder)in
Co-investorsFarvatn VentureY CombinatorInnovation Endeavors
HealthLeap builds data-driven safety systems that identify patients in need of clinical care, helping healthcare providers reach patients who might otherwise be missed.
AI & Machine LearningDigital HealthHealthtech
Josiah(Founder, AI-focused entrepreneur)Jemima Meyer, RD(SA)(Founder)in
Co-investorsHummingbird VenturesMotive ForceTranspose Platform Management
Helix Nanotechnologies develops mRNA-based therapeutics for disease treatment and environmental applications, currently advancing a COVID-19 vaccine candidate for immunocompromised patients and testing interventions targeting climate challenges.
AI & Machine LearningBiotechHealthtechBoston, US
Nikolai Eroshenko(Founder/CSO)in
Co-investorsBascom VenturesBeast VenturesChampion Hill VenturesDCVC (Data Collective)HAWKTAILLifeline Ventures+8 more
Huminly uses engineered enzymes to separate mixed poly-cotton textile waste into pure polyester monomer and pure cotton, enabling textile-to-textile recycling.
Circular EconomyCleantechNew Materials
Nikita Khlystov(Founder and CEO)inSean Hunt(Co-founder and CTO)Nikita Khlystov, Ph.D.(Founder)in
Implexis blends pharmaceutical expertise with automation to deliver impact in the life sciences industry.
AI & Machine LearningBiotechDeep TechEnterprise Software
Dr Youssef AbdallaDr Hannah SchedeDr David ShorthouseDr Abhishek RajbanshiDr Michael Cook
Invitae provides genetic testing services to patients and clinicians across the United States, offering broad test offerings and genetic counseling to inform health decisions at every stage of life.
BiotechDigital HealthHealthtechMedical DevicesSan Francisco, US
Sean George(Executive Officer, Director)inRandal Scott(Executive Officer, Director)Shelly Guyer(Executive Officer)inLee Bendekgey(Executive Officer)inGeoffrey Crouse(Director)
BoardEric Aguiar(Director)in
Co-investorsCivilization Ventures Management, LlcDecheng CapitalManta Ray VenturesOberland CapitalPrefix CapitalTech Wildcatters+1 more
Journey Clinical provides ketamine-assisted psychotherapy (KAP) for depression, anxiety, and PTSD, partnering patients with licensed therapists and medical teams while coordinating with major insurance providers.
Digital HealthMedical DevicesMental Health
Jonathan Sabbagh(Co-founder & Executive Chairman of the Board)inMyriam Barthes(Co-founder & CEO)in
Co-investorsAble PartnersAlleyCorpCoalition OperatorsMantis CapitalPROOFPsyMed Ventures+5 more
Kano Therapeutics develops circular single-stranded DNA (cssDNA) as a genetic payload for gene-editing and other DNA-based therapies, offering an alternative to viral vectors and double-stranded DNA.
BiotechDeep TechCambridge, US
Floris Engelhardt(Executive Officer, Director)John Vroom(Director)
BoardAnn DeWitt(Director)in
Co-investorsLaunchpad Venture GroupMetaplanetThe Engine VenturesVsquared VenturesZAKA VC
Kascaid develops immune-monitoring technology that samples interstitial fluid instead of blood to capture more stable, cell-free molecular signals of immune activity.
BiotechDigital HealthMedical Devices
Kavya Swaminathan(Co-Founder & CEO)inAustin B. Hall(Co-Founder & Chief Product Officer)inScott Ferguson(Co-Founder & Chief Scientific Officer)in
Co-investors2048 VenturesDraper AssociatesSpacecadet Ventures
The site is a Vietnamese-language affiliate/review portal that ranks and rates online lottery ("lô đề") betting operators, offering comparisons of payout ratios, licensing, payment methods, and security.
ConsumerHealthtechMedia & EntertainmentMedical DevicesKitchener, CA
Moufeed Kaddoura(Founder/CEO)inEric Blondeel(Founder/| CTO)in
Co-investorsMetaplanetUpslope VenturesY Combinator1517BoxOne VenturesGarage Capital+1 more
Kin Euphorics makes non-alcoholic functional beverages formulated with adaptogens, nootropics, and botanics intended to affect mood, brain function, and immunity.
ConsumerDirect to ConsumerWellness & Fitness
Jen Batchelor(Founder)in
Co-investorsCanaan PartnersMelitas Ventures LlcTrousdale VenturesTwo Culture CapitalFemale FoundersRefactor Capital
KiraGen Bio develops cell-therapy approaches aimed at treating brain cancers, with a focus on therapies designed to remain functional under suppressive tumor conditions.
AI & Machine LearningBiotechDeep TechHealthtech
Aaron Edwards(Co-Founder & Chief Executive Officer)inRyan Murray, PhD(Founder)in
Co-investors2048 VenturesZAKA VC
Klyne develops binding affinity models for molecular prediction and offers a low-cost virtual screening service aimed at hit discovery and hit-to-lead optimization projects in drug discovery labs.
AI & Machine LearningBiotechDeep Tech
Co-investorsFred Ehrsam
Kunin is a US-based vertically integrated ion-exchange technology company that manufactures ion-exchange resins, develops metal recovery processes, and builds co-product plants at operating mines, smelters, and refineries.
CleantechDeep TechNew Materials
Co-investorsBrickyard
Latch builds data infrastructure and software tools for biological computing, enabling researchers to program and automate biological discovery through high-throughput laboratory automation and machine learning.
AI & Machine LearningBiotechData & InfrastructureDeep Tech
Alfredo Andere(Cofounder)inKyle Giffin(Cofounder)inKenny Workman(Cofounder)in
Co-investorsCoatue ManagementHummingbird VenturesMantis CapitalSwift Ventures
Lazarus builds modular supercritical CO₂ (sCO₂) turbines that ship in a standard container and assemble in weeks, providing onsite power generation for customers such as data centers.
CleantechEnergyHardware
Luke Malcolm(Founder)in
Lively provides AI-powered customer service and support for the benefits administration industry, combining intelligent technology with human representatives to resolve employee and customer inquiries.
AI & Machine LearningEnterprise SoftwareFintechHealthtechHR TechSaaSSan Francisco, US
Alex Cyriac(Founder/CEO)inShobin Uralil(Founder/COO)in
Co-investorsB Capital GroupB4 CapitalCostanoa VenturesFundersClubLobby CapitalOlive Tree Capital+9 more
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Lygos uses genetically engineered microorganisms to produce industrial chemicals from sugar feedstocks, focusing on compounds where fermentation offers cost advantages compared to fossil fuel-based manufacturing.
Climate TechHealthtechSan Francisco, US
Eric Steen(Founder/CSO)inJeffrey A. Dietrich(Executive Officer, Director)inJay D. Keasling(Director)
BoardLeonard Katz(Director)
Co-investorsFundersClubLG Technology VenturesY Combinator10x FoundersFirst Round CapitalIA Ventures+1 more
Powerhouse.bio is a biotechnology company that combines experimental biology with applied machine learning.
AI & Machine LearningBiotechDeep TechLongevity
Mariëlle van Kooten(Co-founder and CEO)inRachel Jacobson(Co-founder and CSO)in
Co-investorsNFX
Manifold Bio combines AI-guided protein design with high-throughput in vivo screening to engineer tissue-targeted biologics and deliver therapeutic payloads to specific organs.
AI & Machine LearningBiotechDeep Tech
Gleb Kuznetsov(Co-Founder & CEO)inPierce Ogden(Co-Founder & CTO)in
Co-investorsPlayground GlobalFPVHorizons VenturesTriatomic Capital
Varda industrializes low Earth orbit by manufacturing pharmaceuticals and other specialized products in space, then returning them to Earth via reusable reentry capsules.
BiotechDeep TechSpace TechEl Segundo, US
Will Bruey(Co-founder)inDelian Asparouhov(Co-founder)in
Co-investorsAlso CapitalCaffeinated CapitalFounders FundKhosla VenturesLux CapitalGeneral Catalyst+25 more
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Meati produces meat alternatives made from mycelium, the root structure of fungi, offering a plant-based protein source with complete amino acids and additional nutritional benefits.
ConsumerFoodTech
Tyler Huggins(Founder)in
Co-investorsBetter Ventures Central LlcBluestein VenturesJoyance PartnersSocial StartsThe March GroupToba Capital+8 more
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Medra builds robotic systems integrated with AI, computer vision, and natural language processing to automate data collection for life science research.
AI & Machine LearningBiotechDeep TechRoboticsSan Francisco, US
Michelle Lee(Co-founder)in
Co-investorsCarbon SiliconFusionHuman CapitalLux CapitalMenlo VenturesMetaplanet+4 more
Merge Labs creates AR/VR learning tools for K-12 education, including the Merge Cube handheld interface and Merge EDU platform, enabling immersive hands-on STEM and science learning in classrooms and educational spaces.
AI & Machine LearningEdTechHardwareSan Antonio, US
Andrew Trickett(Founder)in
Co-investorsGeekdomNew Ground VenturesAccelAdditionBain CapitalInterface Fund+2 more
Merge provides a unified API and integration infrastructure that lets software companies connect their products to hundreds of third-party systems (HRIS, accounting, ticketing, file storage, CRM) and deploy AI agents that take authenticated actions across enterprise tools.
AI & Machine LearningData & InfrastructureDeveloper Tools
Gil Feig(Founder)inShensi Ding(Founder)in
Co-investorsAccelNew Enterprise Associates (NEA)AdditionBain CapitalBain Capital VenturesInterface Fund
Merge Labs is a research lab developing brain-computer interfaces that connect with neurons using molecules instead of electrodes and non-invasive modalities like ultrasound, integrated with AI.
AI & Machine LearningBiotechDeep TechSan Antonio, US
Andrew Trickett(Executive Officer, Director)Franklin Lyons(Executive Officer, Director)
BoardLew Moorman(Director)in
Co-investorsAntiBig Brain HoldingsSciFi VCStarship VenturesBain CapitalBain Capital Ventures+2 more
Metri is a biotech company developing first-in-class, disease-modifying therapeutics for endometriosis and other uterine diseases originating in the endometrium.
BiotechFemTechHealthtech
Ashley Abel(Co-Founder & CEO)inAshley Abel, Ph.D.(Founder)inBerna Sozen, PhD(Academic Co-Founder & SAB Chair)
Co-investorsPace VenturesPillar VC
Microverse is an online education platform that trains people globally for remote work opportunities, with a focus on building collaboration and communication skills needed in distributed teams.
Developer ToolsEdTechFuture of WorkCT, ES
Ariel Camus(Founder)in
Co-investorsAcurio VenturesNorthzoneY CombinatorGeneral CatalystLiquid VenturesSoma Capital
Mindset Health develops digital health programs using hypnotherapy and mind-body medicine to help patients manage gastrointestinal disorders and improve health outcomes.
Digital HealthHealthtechMedical DevicesMental HealthWellness & FitnessMelbourne, AU
Alex Naoumidis(Co-founder & Co-CEO)inChris Naoumidis(Founder)in
Co-investorsAlberts Impact VenturesKing River CapitalPerennial PartnersTenmileY CombinatorAfore Capital+5 more
Molecule operates a blockchain-based platform supporting decentralized science (DeSci), funding research projects and connecting scientists and entrepreneurs.
AI & Machine LearningBiotechCrypto & Web3
Paul Kohlhaas(Founder)in
Co-investorsBackedCompoundInflection.xyzLunar VenturesShine CapitalSignature Ventures+8 more
Molten Industries develops chemical reactor technology that splits natural gas into hydrogen and graphite using electrical resistive heating for battery anode production and industrial hydrogen supply.
Advanced ManufacturingCleantechEnergyNew MaterialsWest Oakland, US
KevininCaleb Boyd(Cofounder)in
Co-investorsBreakthrough Energy VenturesJ4 VenturesMoai CapitalSozo VenturesUnion Square Ventures (USV)UVC Partners
Multiomic Health applies systems biology and data science to omics datasets for drug discovery and development in cardiometabolic and related diseases, working through R&D partnerships with biopharma organizations.
AI & Machine LearningBiotechDigital HealthLondon, GB
Robert Thong(Co-founder & CEO)inAlasdair Thong(Co-founder & Non-Executive Director)inCelia Schell(Chief Clinical Officer & Chief Operating Officer)inMichael Sierra(Chief Scientific Officer)inAriella Cohain(Chief Technology Officer)inEsra Berkol(Chief of Staff)in
Co-investorsHoxton VenturesMMC VenturesVerve VenturesAda Ventures
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Multiply Labs builds robotic systems that automate biologics manufacturing for pharmaceutical companies.
Advanced ManufacturingBiotechDeep TechRoboticsSan Francisco, US
Fred Parietti(Co-Founder & CEO)inAlice Melocchi(Co-Founder & CSO)in
BoardShaun Rodriguez(Director)inMichael Doherty(Director)
Co-investorsGarage CapitalP101 VenturesStrange VenturesY CombinatorZillionizeCasdin Capital+2 more
Nabla is a drug development company that applies design discipline and scientific rigor to the development of new medicines.
AI & Machine LearningBiotechDeep TechHealthtechBoston, US
Surge Biswas(Founder)inFrances Anastassacos(Founder)in
Co-investorsCantos VenturesPillar VCRadical VenturesY CombinatorZetta Venture PartnersBoom Capital Ventures+1 more
Axoneurotech develops neural engineering technology using a biology-first approach at the intersection of biology and engineering.
BiotechDeep TechMedical Devices
Co-investorsVIVES Partners
Noya converts existing industrial equipment such as cooling towers into carbon dioxide capture systems, lowering the initial investment and deployment time required for direct air capture operations.
Advanced ManufacturingClimate TechSan Francisco, US
Josh Santos(Founder)inDaniel Cavero(Founder)inJoshua Santos-Heard(Co-Founder & CEO (Chief Carbon Removal Officer))Daniel Cavero Rodriguez(Co-Founder & CTO)
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BoardAndrew Clare(Director)inFred Wilson(Director)in
Co-investorsLOWERCARBONLowercarbon CapitalOpen Opportunity FundSur VenturesUnion Square Ventures (USV)Y Combinator+2 more
Nurx provides accessible and affordable medications and tests through a digital health platform designed for everyone.
Digital HealthDirect to ConsumerFemTechHealthtechWellness & FitnessNew York City, US
Edvard Engesaeth(Founder)
Co-investorsComcast VenturesDreamers VCForeground CapitalGarage CapitalKleiner PerkinsY Combinator+2 more
Oatly makes oat-based food and drink products, including oat drinks, chilled oat drinks, cooking products, and oatgurt.
Climate TechConsumerFoodTech
Rickard Öste(Founder)Björn Öste(Founder)
Co-investorsCoefficient CapitalDynabrand VenturesFELIX CAPITALIndustrifondenK2 GlobalOyster Bay Venture Capital+8 more
Octant is a therapeutics company that develops small molecule drugs to treat protein misfolding diseases.
AI & Machine LearningBiotechDeep TechMedical DevicesEmeryville, US
Sri Kosuri(Co-founder)inRamsey Homsany(Founder)in
Co-investorsAndreessen Horowitz+ND Capital8VCCarbon SiliconCatalio Capital Management, LPFlucas Ventures+7 more
Onava is a drug discovery company that combines AI-native protein engineering, autonomous orchestration of model training and experimental feedback, and high-throughput functional assays to develop next-generation therapeutics.
AI & Machine LearningBiotechDeep Tech
Ido Calman(CEO & Co-Founder)inSharrol Bachas(CSO & Co-Founder)inHamed Alishahi(Founding Director of Screening Technologies)Zeynep Onder(Founding VP, Operations & Partnerships)in
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Co-investorsMeron Capital
OnePot is a tool for synthesizing molecules, with end-to-end encryption of users' molecular structures.
AI & Machine LearningBiotechDeep Tech
Co-investorsScript Capital
First Contact builds a high-fidelity tactile sensing glove with 847 pressure-sensing taxels per hand running at 240 Hz, including coverage on the sides and tips of the fingers.
Deep TechHardwareRobotics
Ignite provides solar energy solutions across African markets, from access to productivity, designed for rapid deployment and scaling.
Advanced ManufacturingCleantechClimate TechEnergyDakar, SN
Nilmi Senaratna(Founder/CEO)inDan Rosa(Founder/COO)in
Co-investorsY Combinator
Opentrons develops laboratory robots that automate scientific research tasks for scientists and research institutions.
AI & Machine LearningBiotechHardwareHealthtechMedical DevicesRoboticsNew York City, US
Nicholas Wagner(Founder)inWill Canine(Founder/CPO)inChiu Chau(Founder)inLeslie Mitchell(Director)inJames Atwood(Executive Officer, Director)in
BoardAlex Morgan(Director)in
Co-investorsKhosla VenturesLerer HippeauEQUIAMFuture VenturesMetaplanetMillennium New Horizons+7 more
Origami Robotics develops hardware components, specifically gearboxes, to improve general-purpose robotic manipulation by addressing limitations of high-ratio designs in simulation-to-reality transfer and force feedback.
Advanced ManufacturingDeep TechHardwareRoboticsSan Francisco, US
Quanting(Daniel) xie(Founder)inRyan Xie(Founder)in
Co-investorsBeyond Earth VenturesScript CapitalY CombinatorQuantumlight Capital
Persephone develops a synbiotic supplement for infants that combines probiotics (keystone Bifidobacterium strains) with prebiotics found in human breast milk to replenish gut bacteria linked to digestion, immunity, and development.
BiotechConsumerDigital Health
Stephanie Culler(CEO & Co-Founder)inSteve Van Dien(CTO & Co-Founder)
Co-investorsFirst Bight VenturesPropel Bio PartnersY Combinator
Persephone Biosciences develops a synbiotic (probiotic and prebiotic combination) supplement for infants designed to replenish key beneficial gut bacteria.
BiotechFemTechHealthtechSan Diego, US
Stephanie Culler(Founder/CEO)inStephen Van Dien(Founder/CTO)in
Co-investorsBioBritFirst Bight VenturesHemi Ventures, LlcOcampo CapitalY CombinatorDCVC (Data Collective)+1 more
Phylo is an applied research lab studying agentic AI to accelerate biomedical discoveries for scientists.
AI & Machine LearningBiotechDeep TechSaaSStanford, US
Kexin Huang(Founder)in
Co-investorsAndreessen HorowitzHAWKTAILSilicon GardensMenlo VenturesSV Angel
Planet A Foods develops alternative food ingredients using food technology to reduce climate impact in the food industry.
AgTechBiotechClimate TechConsumerFoodTechMunich, DE
Maximilian Marquart(Co-Founder & Chief Executive Officer)inSara Marquart(Co-Founder & Chief Technology Officer)in
Co-investorsBayern KapitalBurda Principal InvestmentsCherry VenturesNucleus CapitalWorld FundY Combinator+3 more
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Plasmidsaurus provides fast DNA and RNA sequencing services for scientists, including whole plasmid, whole genome, amplicon, microbiome, RNA-Seq, and AAV sequencing, with bioinformatics tools and annotated data delivered overnight.
AI & Machine LearningBiotechDeep Tech
Eric Johnson(Founder)inMark Budde(Founder)inJames Stapleton(Founder)in
PNOĒ offers non-invasive breath-based metabolic testing that measures 23 biomarkers to derive metrics like VO2 Max, RMR, and fat-burn, paired with an AI engine that combines the results with wearable, blood, and biometric data to generate personalized nutrition, training, and lifestyle plans.
AI & Machine LearningDigital HealthSports Tech
Co-investorsSocial Starts
Polyphron is using AI and automation to produce human tissue at scale, providing ground-truth data for AI biology and developing therapeutics based on immune-compatible iPSC-derived grafts.
AI & Machine LearningBiotechDeep Tech
Fabio Boniolo(Founder)in
Co-investorsCompoundHumba Ventures
QMatter builds compression algorithms that use a quantum latent space to reduce industrial-scale problems so they run efficiently on quantum and conventional hardware.
Deep TechEnterprise SoftwareQuantum Computing
Alexis Ralli(Founder)inTim Weaving(Founder)in
Quantstamp provides smart contract and blockchain security audits and verification services for Web3 and Web2 projects.
Crypto & Web3CybersecurityEnterprise SoftwareSan Francisco, US
Richard Ma(Founder/CEO)inSteven Stewart(Executive Officer, Director)in
Co-investorsBloccelerate VCDragonflyLegalTechManhattan Venture PartnersMetaplanetMetastable+11 more
Rad AI develops generative AI models and automation solutions specifically designed for radiology and healthcare workflows.
AI & Machine LearningEnterprise SoftwareHealthtechMedical DevicesSan Francisco, US
Dr. Jeff Chang(Co-founder)inDoktor Gurson(Co-founder)in
BoardStuart Peterson(Director)inBruce Armstrong(Director)in
Co-investorsAlpha PartnersArray Ventures Management LlcArtis VenturesCity LightCorewell Health VenturesGMO VenturePartners+9 more
Range Bio (Range Biotechnologies) develops next-generation diagnostics using translational proteomics for applications in human health.
BiotechHealthtechMedical Devices
Brandon Wilson, Ph.D.(Co-founder & CEO)Brandon Wilson(Co-founder & CEO)in
Co-investorsArtis VenturesCivilization Ventures Management, LlcHAWKTAILPage One VenturesPear VCPillar
Rebellyous develops plant-based chicken nuggets and proprietary manufacturing systems designed to enable efficient, clean food production with improved working conditions.
Advanced ManufacturingClimate TechFoodTechHealthtechImpact & Social GoodSeattle, US
Christie Lagally(Founder/CEO)in
Co-investorsAgronomicsBlue Horizon CorporationClear Current CapitalPortfoliaSinai Capital PartnersThe Venture Collective+6 more
Red Queen Bio builds an AI-powered biodefense system that rapidly designs and manufactures countermeasures against emerging biological threats, enabling faster defensive responses to evolving pathogenic risks.
AI & Machine LearningBiotechDefense Tech
Hannu Rajaniemi(Executive Director)inNikolai Eroshenko(CEO)in
Co-investorsCompoundLongeVCThe Venture CollectiveCerberus Ventures
ResistanceBio develops treatments to address drug resistance in cancer patients.
BiotechHealthtechSan Francisco, US
Nicholas Goldner(CEO/Founder)inChristopher Bulow(Founder)inKYLE LAPHAM(Executive Officer, Director)
BoardOMRI AMIRAV-DRORY(Director)in
Co-investorsY CombinatorNFX
Science Corporation develops brain-computer interface and neural engineering technology to restore vision, cognition, and mobility to patients with debilitating conditions.
AI & Machine LearningBiotechDeep TechDigital HealthMedical DevicesAlameda, US
Max Hodak(Chief Executive Officer)
Co-investorsage1Artis VenturesAvalanche VCBeyond CapitalConversion CapitalDuke Capital Partners+9 more
Sift Biosciences develops T-cell immunotherapies for cancer and autoimmune diseases, using an AI-driven discovery platform combined with metagenomics and high-throughput cellular screening to identify microbially derived molecules that activate memory T cells.
AI & Machine LearningBiotechHealthtechSan Carlos, US
Yue Clare Lou(Co-Founder & CEO)in
BoardKevin Barrett(Director)inAltar Munis(Director)
Co-investorsEisai Innovation, Inc.SBI HoldingsFREEFLOW
Substack is a publishing platform that allows writers to create newsletters, cultivate audiences, and earn revenue through reader subscriptions.
Enterprise SoftwareMarketing TechMarketplacesSan Francisco, US
Chris Best(Founder/CEO)inJairaj Sethi(Founder)inHamish McKenzie(Founder/COO)in
BoardAndrew Chen(Director)in
Co-investorsConnetic VenturesFundersClubJ17 CapitalWisdom VenturesWonder VenturesY Combinator+4 more
Talus develops a proprietary platform that measures and modulates the regulome—the body's gene expression control system—in native cellular contexts.
AI & Machine LearningBiotechDeep TechHealthtechSeattle, US
Alex Federation(Founder)inLindsay Pino(Founder)inAlex Federation, Ph.D.(Chief Executive Officer & Co-Founder)Lindsay Pino, Ph.D.(Chief Technology Officer & Co-Founder)
BoardOmri Amirav-Drory(Director)inJ. Seth Strattan(Director)in
Co-investorsFarvatn VentureFundersClubNFXTwo Bear CapitalY CombinatorBoxOne Ventures
Tangible provides AI-powered quantity extraction from architectural drawings and building models to give preconstruction teams live materials data for cost and carbon impact analysis.
AI & Machine LearningClimate TechConstruction Tech
Co-investorsFlybridge Capital PartnersFoundamentalFuture Positive CapitalPi LabsSuffolk TechnologiesPale Blue Dot
A later venture from the Cruise founding team that Spark partnered on again.
Kyle Vogt(Founder)inParil Jain(Founder)in
Co-investorsDaft CapitalFactorial FundsMaven VenturesMVP VenturesSpark CapitalSV Angel+3 more
Tierra Biosciences develops high-performance protein design technology, serving biotechnology and pharmaceutical industries.
Biotech
Co-investorsBeresford VenturesCreative VenturesFREEFLOWMaterial ImpactHumboldtKdT Ventures+1 more
Tipply develops causal world models and AI systems that control flight systems, enabling aircraft to make autonomous, dynamics-driven decisions.
AI & Machine LearningDeep TechRobotics
TwoStep Therapeutics is a Stanford spinout developing targeted cancer therapies, including peptide-based drug conjugates and radioligand programs built on a tumor-targeting peptide platform.
BiotechHealthtechSan Carlos, US
Caitlyn Miller(CEO & Co-Founder)inJennifer Cochran(Co-Founder)Carolyn Bertozzi(Co-Founder)Ronald Levy(Co-Founder)
BoardOmri Amirav-Drory(Director)inJohn Prufeta(Director)in
Co-investors2048 VenturesMedical Excellence CapitalNFX
Type III, Inc. designs and manufactures hardware products such as its Rugged Mini Mount, offering rapid prototyping, low-volume production, and specialized hardware builds.
Advanced ManufacturingHardwareHuntington Beach, US
Daniel Moore(Executive Officer, Director)
Co-investorsBlack FlagHarpoon Ventures
Ukama provides tools and infrastructure that enable organizations to design and deploy their own cellular networks without requiring telecommunications expertise.
Enterprise SoftwareHardwareSaaSSan Francisco, US
Kashif Ali(Founder)in
Co-investorsWayfinder VenturesY Combinator
Unspun develops 3D weaving technology and software for apparel and textile manufacturing, enabling fast, automated, and low-waste garment production for brands and manufacturers.
Advanced ManufacturingCleantechClimate TechEmeryville, US
Walden Hoi Ming Lam(Executive Officer, Director)Beth Esponnette(Founder)inKevin Martin(Founder)inARNE ARENS(Executive Officer, Director)in
BoardMilo Werner(Director)inShuo Yang(Director)in
Co-investorsCity LightDCVC (Data Collective)E12 Venture Capital, LlcEvolution VenturesKyber Knight CapitalLOWERCARBON+9 more
Upside Foods produces cultivated meat using cell-based technology.
BiotechFoodTechSan Francisco, US
Uma Valeti(Founder & CEO)in
Co-investorsAlwyn CapitalCPT CapitalDentsu VenturesFuture VenturesJoyance PartnersMcWin Capital Partners+10 more
Using few-shot learning to design better drug candidates, faster
AI & Machine LearningBiotechData & InfrastructureDeep TechHealthtechMontréal, CA
Daniel Cohen(Founder)in
Co-investorsAir Street CapitalAmplify CapitalBrightspark VenturesFounderFuelFront Row VenturesPanache Ventures+3 more
Valence Labs is an AI research engine that develops computational models to predict cellular responses to genetic and chemical interventions for drug discovery.
AI & Machine LearningBiotechDeep Tech
Co-investorsConvergent Ventures
Vcreate uses machine learning and single-cell sequencing screening assays to engineer human T-cell receptors (TCRs) for TCR-based therapies that target disease-specific antigens, including rare cancer mutations.
AI & Machine LearningBiotechDeep Tech
Ethan Fast(Founder)in
Velocity Bio is developing a biophysical assay platform designed to generate larger-scale, higher-quality data for early-stage drug discovery.
AI & Machine LearningBiotechDeep Tech
Co-investorsPear VC
Vercept built AI software that runs locally on personal computers to understand user screens and workflows, enabling direct interaction with user intent.
AI & Machine LearningDeveloper Tools
Kiana EhsaniinLuca Weihs(Founder)inRoss Girshick
Co-investorsAllen Institute for AI (AI2) IncubatorAllen Institute for Artificial Intelligence Incubator (AI2)Madrona Venture GroupPoint Nine
Watney Labs develops a foundation model (GracE) that integrates plant genetics and environmental data into a platform for plant breeders and seed companies to simulate how crop varieties will perform in new locations and seasons.
AgTechAI & Machine LearningDeep Tech
WattAir is a company applying scientific research and development to water-related challenges across water-intensive sectors.
Cleantech
Joseph Mooney(Cofounder)in
Waypoint Bio uses artificial intelligence, computer vision, and pooled screening to conduct deep phenotyping across thousands of cell therapy designs, enabling the discovery and optimization of superior cell therapy candidates for development.
AI & Machine LearningBiotechDeep Tech
Xinchen Wang, Ph.D.(Co-founder & CEO)David Phizicky, Ph.D.(Co-founder & CSO)Xinchen Wang(Founder)in
Co-investorsAmplify PartnersHummingbird VenturesMBX CapitalMitsui Global InvestmentRecode VenturesAmplify Partners CV+2 more
WorkEQ provides executive function coaching, workplace onboarding training, and workshops that teach skills such as critical thinking, organization, time management, and emotional intelligence.
EdTechFuture of WorkHR Tech
Jodi Roth-Saks(Founder)in
World is a decentralized protocol providing universal proof of human identity for the internet, along with financial infrastructure and a native token called WLD, operated through the World App and World Chain blockchain.
Crypto & Web3FintechSector AgnosticSan Francisco, US
Sam Altman(Co-founder & Chairman, Tools for Humanity)Alex Blania(Co-founder & CEO, Tools for Humanity)inMax Novendstern(Co-founder, Tools for Humanity)in
Co-investorsAndreessen HorowitzBain Capital CryptoBlockchain CapitalKhosla Ventures1confirmationCoinFund+6 more
Yuri develops in-house space labs and ground simulators that use microgravity for life sciences research, supporting drug development and cell-based therapies.
BiotechDeep TechSpace TechMeckenbeuren, DE
Christian Bruderrek(Founder)in
Co-investorsAPEX VenturesNucleus CapitalThe Venture Collective
Zero Acre Farms produces cooking oils optimized for chefs and restaurants, using organic fera fruit oil as an alternative to seed oils with superior heat stability, cleaner taste, and healthier fat profiles.
AgTechFoodTechImpact & Social GoodSan Francisco, US
Jeff Nobbs(Founder & CEO)in
Co-investorsCollaborative FundCornucopian Capital ManagementDesigner FundHabitat PartnersHyperguapJuniper+8 more
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Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Advancing reproductive medicineAirwattBirdwoodBlueprint Bryan JohnsonBrightseed, Inc.Cypher AIDeck BioDevonian SystemsKlona BiotechMemphis MeatsMetalafNeela BiotechSculptaSeattle Food TechSerova BioTera
Exits · 8
4 IPOs · 4 acquisitions · showing 4BillionToOneNASDAQ: BLLNHealth CatalystNASDAQ: HCATMednaxNYSE: MDValence Discoveryacq. by Recursion
Portfolio news
latest coverage across their companiesSubstack · en.wikipedia.org · Aug 26, 2026
Digit · seekingalpha.com · Aug 22, 2026
Oatly · greenqueen.com.hk · Aug 19, 2026
Antora Energy · intelligence360.news · Aug 17, 2026
Zero Acre Farms · zeroacre.com · Aug 14, 2026
Merge Labs · tradeflockasia.com · Aug 13, 2026
Dipole Labs · ycombinator.com · Aug 13, 2026
Frequently asked questions
- How many investments has Fifty Years made?
- Fifty Years has 165 tracked investments, 8 of which have exited, including 11 dated in the last 24 months.
- What stage does Fifty Years invest at?
- Fifty Years invests at the Pre-Seed, Seed stages.
- What is Fifty Years's typical check size?
- Fifty Years typically writes checks of $250K – $2M.
- What sectors does Fifty Years focus on?
- Fifty Years focuses on AgTech, AI & Machine Learning, Biotech, Climate Tech, Deep Tech.
- Where is Fifty Years located?
- Fifty Years is headquartered in San Francisco, US.
- Does Fifty Years lead rounds?
- Fifty Years typically participates in rounds rather than leading them.
- Who does Fifty Years co-invest with?
- Fifty Years most often shares deals with Y Combinator, Metaplanet, FundersClub, among 439 tracked co-investors.
Media · Podcasts & interviews
featuring the teamHow to Spinout from Academic Labs with Alex Teng of Fifty Years
The Climate Vine · Alex Teng
Mr. and Mrs: Fifty Years: Sneak Peek Into The Life of Ela Madej and Seth Bannon I Slush 2021
Slush · Ela Madej
Sean Hunt (Solugen) & Seth Bannon (Fifty Years): From Academia to Entrepreneurship | Slush 2021
Slush · Seth Bannon
Impact Investing 🌟 w/ Seth Bannon - Founding Partner @ Fifty Years | BIOS
BIOS · Seth Bannon
New Type of Therapeutic Unicorns 🎉 w/ Seth Bannon - Founding Partner @ Fifty Years | BIOS
BIOS · Seth Bannon
What Will Biotech Look Like in 2050? ✨ w/ Seth Bannon - Founding Partner @ Fifty Years | BIOS
BIOS · Seth Bannon
Co-investors · 54
Refactor is a seed-stage venture firm run as a solo capitalist by Zal, backing founders building hard tech companies that address real-world problems.
SV Angel is a firm that has backed startup founders since the 1990s, leveraging a large network of founders, industry leaders, and regulators to support portfolio companies.
Liquid 2 is an early- and growth-stage venture capital firm that invests in founders across all sectors of technology, providing capital along with support from a network of operators.
Union Square Ventures is a venture capital firm based in New York City that invests at the edge of large markets undergoing transformation from technological and societal pressures.
Lux Capital is a venture capital firm that backs founders building transformative deep technologies, having been among the first investors in category-defining companies across AI, robotics, biotech, defense, and infrastructure.
Preston-Werner Ventures is a venture capital firm associated with Tom Preston-Werner, cofounder of GitHub, who has moved into venture investing.
Sequoia Capital is a venture capital firm that partners with founders to build technology companies.
UpHonest Capital is a Silicon Valley-based investment firm founded in 2017 that supports cross-border entrepreneurship and investment between China and the United States, and runs media, scout, and incubation programs.
Amplify Partners is a venture capital firm that backs technical founders — engineers, researchers, and scientists — building companies across AI/ML, data infrastructure, developer tools, and life sciences.
Winklevoss Capital is an investment firm that backs founders working on hard problems in critical, frontier technology domains.
Founders Fund is a venture capital firm that backs technology companies building transformative products.
BCV Labs is the platform and hands-on support arm of Bain Capital Ventures, providing portfolio founders with go-to-market strategy, brand development, hiring assistance, and customer introductions.
▶42 more co-investors
Avalanche VCBlueYard CapitalCraft VenturesSusa VenturesOffline VenturesLowercase CapitalThrive CapitalM13Uncorrelated VenturesArray Ventures Management LlcAnorak VenturesMango CapitalPlayground GlobalHelium-3 VenturesHighbury HoldingsFoundamentalNIVAir Street CapitalPi LabsCambridge Angels groupInflection.xyzKrakenPioneerBuckley Ventures Management Company LlcHack VCLightbankHaun VenturesDawn CapitalNotation CapitalSweet CapitalStealth CapitalAmbush Capital8090 IndustriesEvolve VC FundsGemini Israel VenturesAmino CollectivePTC PolymarketCloudflare, Inc.Cerulean VenturesPalo Santo VCMystic VenturesAxial VC
Firms observed investing alongside Fifty Years, from public investor directories. Shared companies are the overlap with Fifty Years's recorded portfolio.
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