Overwater Ventures Llc
Palo Alto · Pre-Seed–Seed · 1 people tracked
Investment thesis
Overwater invests in breakthrough technology companies that radically improve global health and well-being. The firm targets innovations in healthcare infrastructure, women and family health, human optimization, next-gen medicine, care delivery, preventive healthcare, and aging/longevity, as well as systems-level transformation in energy, food, materials, manufacturing, and circular economy. The firm seeks founders building the most impactful solutions to create a healthier, more resilient world, often making first institutional investments pre-product or pre-revenue.
Source: firm website, verified Jul 20, 2026.
Team · 1 people
from the firm's website
Kristina Simmons has extensive experience in building, advising, and investing across consumer and technology sectors. She was an early member of lululemon's e-commerce team and led emerging products initiatives, subsequently became a partner at Andreessen Horowitz supporting portfolio company growth, and served as Chief of Staff and investment partner at Khosla Ventures. She founded Overwater Ventures to provide founder-centric venture support.
What they invest in
from 16 of 27 portfolio companiesHealthtech ×11Digital Health ×7AI & Machine Learning ×6Biotech ×4FoodTech ×3Medical Devices ×3AgTech ×2FemTech ×2
HQs:United States×4
Investments · 27 tracked
founders shown can be your intro pathFeanix Autopilot is an AI-powered platform that combines whole-genome sequencing, farm performance data, and economics to provide herd-level breeding and culling recommendations for dairy farmers. The system integrates existing farm management tools and generates ranked, priced decisions to maximize farm profitability.
Advanced ManufacturingAgTechAI & Machine LearningAsheville, US
Certuma builds autonomous clinical infrastructure that combines LLM reasoning with deterministic verification to deliver physician-reviewed clinical decisions at scale, addressing the global physician shortage by validating clinical workflows as infrastructure for remote patient care.
AI & Machine LearningDigital HealthHealthtech
Martin Varsavsky(Chief Executive Officer)Armando Cuesta(Chief Medical Officer)Joe Scanlin(Chief Technology Officer)Jesus Mejia(Chief Legal Officer)
Trial Library is an AI-native platform that integrates clinical trials into routine healthcare by connecting patients, providers, payers, and pharmaceutical sponsors. The platform accelerates patient enrollment and trial access across health systems, clinics, and specialty practices.
AI & Machine LearningDigital HealthHealthtech
Quorum Bio develops genetic engineering tools for precision fermentation, enabling the production of complex natural products using engineered non-model microbes. The company targets the food, beverage, wellness, and agriculture industries with nature-based ingredients and biocontrols to replace synthetic chemicals.
AgTechBiotechFoodTech
Sudharsan Dwarknath, Ph.D(Co-Founder & CEO)Yasuo Yoshikuni, Ph.D(Co-Founder & Advisor)
Fellow provides mail-in semen analysis testing for patients and fertility clinics, with results delivered in under 2 business days from a CLIA-certified laboratory. The service supports vasectomy verification and fertility testing for patients and clinical partners including urologists and reproductive specialists.
Digital HealthHealthtechMedical Devices
Hyfé refines food waste to extract specialty ingredients and chemical compounds for use in food, beverage, personal care, nutraceutical, and biomanufactured products. The company converts glucose from agricultural waste into alternatives to petroleum-derived materials for industrial production.
BiotechCircular EconomyFoodTech
Overstory provides AI-powered vegetation intelligence using satellite and aerial imagery to help electric utilities optimize vegetation management programs and reduce infrastructure risk from trees and encroachment. The company serves utility operators in North America and Europe, enabling data-driven decision-making to improve grid reliability and manage costs.
AI & Machine LearningClimate TechEnergy
Conceive provides 24/7 access to fertility nurses and coaches via text and app for personalized fertility coaching, support, and expert-led guidance for people navigating conception, testing, and fertility treatment.
Digital HealthFemTechHealthtech
<UNKNOWN>(Founder & CEO)
BeSound provides advanced ultrasound imaging for breast cancer screening using AI-powered detection technology that does not require radiation. The company serves women seeking early breast cancer detection, particularly those with dense breast tissue who may be missed by traditional mammography.
AI & Machine LearningDigital HealthHealthtechLos Angeles, US
Bailey Renger(Founder & CEO)
Gameto develops cell therapy and reproductive technologies to treat infertility and improve women's health outcomes. The company uses stem cell biology and in vitro maturation techniques to create innovative solutions for patients seeking family-building options.
BiotechFemTechHealthtechMedical DevicesAustin, US
Dina Turner(Co-founder & Chief Executive Officer)Martin Varsavsky(Co-founder & Chairman)
Adaptyx develops a minimally-invasive wearable patch that continuously monitors biomarkers in interstitial fluid to support clinical decision-making and prevent complications and readmissions. The technology targets healthcare providers and clinicians seeking continuous patient monitoring beyond traditional lab draws and periodic clinic visits.
Deep TechHealthtechMedical Devices
Tiny Health provides microbiome testing kits and personalized health reports for families from pregnancy through adulthood, focusing on gut health optimization to address conditions like eczema, allergies, IBS, and constipation. The company emphasizes early testing during a child's first 1,000 days of life and offers diet, supplement, and lifestyle recommendations based on test results from CLIA-certified laboratory analysis.
Digital HealthHealthtechWellness & Fitness
Olio Labs develops drug combination therapies using machine learning to identify treatments that target multiple interacting proteins simultaneously, with initial candidates focused on obesity treatment. The company aims to create pharmaceutical solutions that achieve greater efficacy and lower side effect profiles than existing single-target medications.
BiotechHealthtech
RTHM combines artificial intelligence with clinical expertise to help patients with complex and unexplained illnesses find faster paths to diagnosis and treatment. The platform serves patients and healthcare providers within the digital health and diagnostics industry.
AI & Machine LearningDigital HealthHealthtechSan Francisco, US
Ryan Kellogg(CEO and Cofounder)inJennifer Curtin(Chief Medical Officer and Cofounder)inMichael Snyder(Scientific Cofounder)Eduardo Bohrer(COO/CFO and Cofounder)
tendercare is a free platform for family caregivers that organizes information, coordinates care, and connects users to vetted professional services for elder and adult care. The company generates revenue through memberships of vetted eldercare service providers in its Trusted Network directory.
HealthtechImpact & Social GoodWellness & Fitness
Shauna Sweeney(Founder & CEO)
Zero Acre Farms produces cooking oils optimized for chefs and restaurants, using organic fera fruit oil as an alternative to seed oils with superior heat stability, cleaner taste, and healthier fat profiles.
FoodTechImpact & Social Good
Frequently asked questions
- What stage does Overwater Ventures Llc invest at?
- Overwater Ventures Llc invests at the Pre-Seed, Seed stages.
- What is Overwater Ventures Llc's typical check size?
- Overwater Ventures Llc typically writes checks of $500K – $2M.
- What sectors does Overwater Ventures Llc focus on?
- Overwater Ventures Llc focuses on AI & Machine Learning, Biotech, Circular Economy, Climate Tech, Digital Health, Energy, FemTech, FoodTech, Healthtech, Longevity, New Materials, Sector Agnostic.
- Where is Overwater Ventures Llc located?
- Overwater Ventures Llc is headquartered in Palo Alto, US.
- Does Overwater Ventures Llc lead rounds?
- Yes, Overwater Ventures Llc leads investment rounds.
Similar investors
Everywhere Ventures is an early-stage venture capital firm backing founders across diverse sectors and geographies. The firm provides pre-seed and seed capital, actively supports portfolio companies through its founder community, and has demonstrated success in introducing investments to subsequent funding rounds.
Data Collective identifies and supports ambitious company founders developing technology-driven solutions. The firm focuses on companies using innovation to restore predictability in an unstable world, with demonstrated expertise across clean energy, gene therapy, sustainable agriculture, and machine learning applications in healthcare.
Innovestor is a Nordic investment group active across early-stage platforms including Angel CoFund, Life Science Fund, and Growth Fund III. The firm completed 74 investments in 2025 (23 initial and 51 follow-on rounds) and achieved a €24 million real estate exit. Innovestor also operates Energy Storage and Corporate Venturing investment platforms.
Snatched Ventures is an emerging manager focused on deep technology investments, leveraging blue-chip venture and corporate networks alongside extensive investing experience.
ICI Fund is a US-based venture capital firm that invests in Israeli founders developing deep technology and enterprise software solutions powered by artificial intelligence. The firm focuses on B2B pre-seed and seed stage companies, leads rounds, and actively supports portfolio company growth in the US market through its network of business executives.