OpenSky Ventures
Venture capitalLos Angeles · Pre-Seed–Series A · 3 people tracked
Investment thesis
OpenSky Ventures backs early-stage companies redefining commerce, targeting recession-resistant, disruptive commerce enablement technology firms and consumer brands operating in large or fast-growing markets with high repeat purchase. The team looks for experienced founders with seasoned teams and credible go-to-market strategies, investing at pre-seed, seed, and opportunistically at Series A when there are positive traction signals such as client testimonials, a growing subscription base, and healthy KPIs. As former operators who scaled companies from zero to $100m+, the partners offer hands-on support across fundraising, demand generation, talent, operations, and subject-matter expertise.
Source: firm website, verified Aug 3, 2026.
Team · 3 people
from the firm's websiteWhat they invest in
from 2 of 42 portfolio companiesAI & Machine Learning ×2AdTech ×1Biotech ×1Gaming ×1Medical Devices ×1
HQs:United States×3
Investments · 42 tracked
founders shown can be your intro pathBoston, US
Board seatJoshua Resnick· per SEC Form D · $32M raise · filed Dec 2022
Avilar develops protein degrader drugs targeting extracellular and membrane-bound proteins, using a novel class called ATACs that harness endolysosomal degradation machinery.
AI & Machine LearningBiotechMedical DevicesWaltham, US
THERESA CAMERON(Director)PAULINA HILL(Director)MARTIN FREED(Director)STEPHANIE TOZZO(Executive Officer)PHIL GRAHAM(Executive Officer)MILIND DESHPANDE(Director)
Board seatJoshua Resnick· per SEC Form D · $75.3M raise · filed Feb 2023
Lexington, US
Board seatJoshua Resnick· per SEC Form D · $120.1M raise · filed Dec 2025
Agentic AI code-based visualization tool
The 'Bloomberg Terminal' for retail
Ethically-sourced, premium tinned seafood
Improves brand rankings in AI search
Premium hummus for health conscious consumers
Modern accounting for start-ups
Converting unsold fashion inventory into sales
Customer information enrichment platform
Streamlining the shipping process for e-commerce brands
Smarter, more efficient A/B testing for ecommerce storefronts on Shopify
AI-powered community management platform
Supremely absorbable liposomal supplements powered by avocado oil
Doctor developed, plant powered, Rx alternatives
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Frequently asked questions
- What stage does OpenSky Ventures invest at?
- OpenSky Ventures invests at the Pre-Seed, Seed, Series A stages.
- What sectors does OpenSky Ventures focus on?
- OpenSky Ventures focuses on AI & Machine Learning, Consumer, Direct to Consumer, E-commerce, Fintech, FoodTech, Retail Tech, SaaS.
- Where is OpenSky Ventures located?
- OpenSky Ventures is headquartered in Los Angeles, US.
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