Illumina Ventures
Foster City · 23 people tracked
Investment thesis
Illumina Ventures invests in early-stage genomics and precision health companies developing transformative life sciences tools including single-cell analysis, spatial biology, multi-omic profiling, synthetic biology, and molecular characterization. The firm leverages independent management, deep domain expertise from decades in genomics, strong operating experience, and strategic alignment with Illumina to identify and nurture companies positioned to transform healthcare. Through Illumina Ventures Labs, the firm accelerates portfolio companies via capital, sequencing access, mentorship, and fully equipped genomics laboratory capabilities.
Source: firm website, verified Jul 20, 2026.
Team · 23 people
from the firm's website
What they invest in
from 34 of 42 portfolio companiesBiotech ×30Deep Tech ×14Medical Devices ×14AI & Machine Learning ×12Digital Health ×9Healthtech ×5AgTech ×2Climate Tech ×1
HQs:United States×8Sweden×1
Investments · 42 tracked
founders shown can be your intro pathPrecede Biosciences develops a blood-based diagnostic platform that profiles gene expression from cell-free DNA to reveal disease biology at the transcriptional level for drug developers and clinical trials. The platform enables non-invasive patient selection and longitudinal tracking of disease mechanisms in oncology and other therapeutic areas.
AI & Machine LearningBiotechDigital HealthBoston, US
Rehan Verjee(Co-Founder, Chief Executive Officer, Board Director)Sylvan Baca(Co-Founder; Assistant Professor of Medicine, Dana-Farber Cancer Institute)Toni Choueiri(Co-Founder; Director, Lank Center for GU Oncology, Dana-Farber Cancer Institute)Matthew Freedman(Co-Founder; Professor of Medicine, Dana-Farber Cancer Institute)
Actym develops engineered bacterial therapeutics for cancer and fibrotic disease treatment, using a proprietary STACT™ platform based on Salmonella typhimurium as a delivery vehicle for localized therapeutic payloads.
BiotechDigital HealthMedical Devices
Adventris is a biotechnology company developing cancer immunotherapy treatments.
BiotechHealthtechBaltimore, US
Jen Herbach(Founder)inWilliam Collis(Founder)inMark Yarchoan(Founder)
Arima Genomics develops DNA-based cancer diagnostics that combine genomic sequence with structural information to detect cancer-driving mutations and rearrangements. The company delivers clinical testing services (Aventa) for oncologists and partners with biopharma teams to identify therapeutic biomarkers.
BiotechDigital HealthMedical Devices
Attovia develops precision biologics using its ATTOBODY platform for patients with immune-mediated diseases. The company creates novel complex biologic medicines through modular protein design.
BiotechDigital Health
Broken String Bio develops genome-wide on- and off-target analysis software and sequencing technology for gene editing research and development. The platform serves biotech and pharmaceutical companies conducting gene editing discovery, optimization, and characterization across diverse cell types and nuclease systems.
BiotechDeep TechMedical Devices
Bullseye Biosciences discovers drug molecules directly in living cells using directed evolution to target difficult intracellular proteins and protein interactions implicated in cancer and other serious diseases. The platform links molecular activity to biological function from the outset, avoiding the discovery-to-development gap typical of conventional in vitro screening.
AI & Machine LearningBiotechDeep Tech
Castle Biosciences develops genomic tests that provide personalized biological information to inform disease diagnosis, treatment selection, and follow-up care decisions for healthcare providers and patients. The company operates in precision genomics and clinical diagnostics focused on improving patient outcomes.
BiotechDigital HealthMedical Devices
CubaseBio develops spatial biology tools that enable three-dimensional analysis of biological samples at scale, for drug discovery and biological research.
BiotechDeep TechStockholm, SE
DeepSeq uses AI to design biologics by analyzing vast numbers of protein interactions to predict affinity, specificity, immunogenicity, pharmacokinetics, and manufacturability. The platform serves pharmaceutical and biotech companies seeking faster drug development with improved predictability.
AI & Machine LearningBiotechDeep Tech
Encoded develops gene therapies for neurological disorders through an integrated platform approach. The company focuses on translating discoveries from research through clinical development and commercialization.
Biotech
Fluent Bio develops software for analyzing single-cell RNA sequencing data, producing count matrices and diagnostic outputs for researchers using Illumina sequencing libraries. The software is designed for genomics and life science researchers working with single-cell gene expression data.
BiotechDeveloper Tools
Genome Medical provides telehealth-enabled genetic services, including counseling, testing, and clinical trial access, primarily for individuals with rare conditions. The company partners with hospitals, health systems, and life sciences organizations to expand access to expert genetic guidance.
Digital HealthHealthtech
Hepta develops LiquidTransformer, an AI platform for analyzing cell-free DNA fragments in blood to detect chronic disease molecular signals. The platform uses transformer-based models with attention mechanisms to identify disease biomarkers from liquid biopsy samples.
AI & Machine LearningBiotechHealthtech
Infinity Bio develops molecular indexing technology to decode antibody-antigen binding interactions for research and therapeutic applications in the biotech field.
Biotech
Integrated Biosciences develops a platform for small molecule drug discovery targeting age-related diseases by combining optogenetics, chemistry, and AI to probe disease biology with precision and explore chemical space systematically.
AI & Machine LearningBiotechLongevity
Lightcast develops Envisia, a next-generation platform for single-cell functional screening and analysis that enables researchers to study biomolecule secretion, cell-cell interactions, and targeted cell killing at scale. The platform serves biotech and pharmaceutical companies working on therapeutic discovery and development.
AI & Machine LearningBiotechDeep Tech
Lightcast provides a next-generation single-cell functional analysis platform called Envisia that enables massively parallel profiling of cell-cell interactions and biomolecule secretion at scale. The platform serves researchers and therapeutics developers studying functional biology for applications in antibody discovery, cellular therapies, and immunotherapy development.
BiotechDeep TechMedical Devices
NanoCellect manufactures microfluidic cell sorting systems for laboratory and research applications. The company's WOLF sorters use low-pressure microfluidics technology to sort cells with high viability and minimal damage for stem cell research and cell biology applications.
BiotechMedical Devices
NuCicer develops improved crop varieties through selective breeding, starting with high-protein chickpeas designed for better nutrition. The company uses predictive breeding and genetic diversity to optimize crops for specific nutritional outcomes rather than yield.
AgTechAI & Machine LearningFoodTechDavis, US
Oncko develops machine learning and experimental platforms to discover optimized multi-drug cancer treatment combinations by screening against resistance mechanisms. The company serves oncology drug developers seeking to identify efficacious combination regimens for cancer indications.
AI & Machine LearningBiotechDeep Tech
Atray Dixit(Co-founder, CEO)inBill Grossman(Co-founder, Strategic Advisor)in
Pattern develops rapid diagnostic testing for bacterial infections using single-cell microbiology to identify pathogens and antibiotic susceptibility in hours rather than days. The company serves hospitals and clinical settings to reduce unnecessary antibiotic prescriptions and combat antibiotic resistance.
BiotechDigital HealthMedical Devices
Pluton develops a soil-surface biological nutrient system powered by photosynthetic microbes that delivers nitrogen and improves phosphorus availability for crops while reducing nutrient loss. The company targets conventional agricultural nutrient programs and aims to integrate with existing farming practices.
AgTechClimate TechDeep Tech
Predicta develops a molecular insights platform for blood cancer care that generates genomic and immune profiling from blood samples to guide treatment decisions and monitor disease evolution. The platform combines whole-genome sequencing of circulating tumor cells with single-cell immune profiling to help clinicians and researchers understand disease biology and track treatment response in hematological malignancies.
BiotechDigital HealthMedical DevicesCambridge, US
Protillion is a biotech company that appears to focus on antibody engineering and platform technology for drug development. The company employs scientists, bioinformaticians, and hardware engineers to develop tools and platforms in the life sciences space.
AI & Machine LearningBiotechDeep TechCarlsbad, US
Robert Hollingsworth(Chief Scientific Officer)Curtis Layton(CEO/Co-Founder)David Walt(Co-Founder)Will Greenleaf(Co-Founder)
Redshift Bio develops real-time monitoring technology for biomolecular structure and concentration analysis in biopharmaceutical development and manufacturing. The platform enables pharmaceutical and biotech companies to make earlier decisions by providing direct structural insights during production processes.
BiotechDeep TechEnterprise Software
Serinus Biosciences uses AI and systems biology to design drug combinations that overcome cancer cells' resistance to existing treatments, targeting safer and more effective therapeutic options.
BiotechHealthtechNew York City, US
SonoThera develops a nonviral, ultrasound-mediated gene delivery technology to safely deliver genetic material to targeted sites in the body. The company addresses limitations in existing genetic medicine approaches for patients across various therapeutic applications.
BiotechDeep TechMedical Devices
Syntax Bio develops a discovery platform that accelerates stem cell-derived therapies by using its proprietary Cellgorithm technology to control and direct cell differentiation. The platform enables biopharma companies to speed up cell therapy development, reduce manufacturing costs, and expand their pipeline of potential treatments.
BiotechDeep TechMedical Devices
Medical Devices
Kallyope discovers and develops novel therapeutics targeting previously unexplored neural networks, with lead programs in acute migraine treatment and novel metabolism disorders. The company leverages its proprietary Klarity platform to identify differentiated drug candidates for patients with challenging diseases.
BiotechDeep TechMedical DevicesNew York City, US
Kodikaz develops Zip-Code, a non-viral cell-specific delivery platform for gene therapy applications, particularly focused on oncology and cancer treatments. The company serves oncologists and patients with cancer seeking advanced therapeutic solutions.
AI & Machine LearningBiotechMedical DevicesAtlanta, US
Anthony Johnson(Co-Founder & CEO)Dr. Leon Bernal-Mizrachi(Co-Founder, CSO)
DELFI Diagnostics develops FirstLook Lung, a blood-based laboratory test for lung cancer screening that identifies genome-wide alterations in individuals eligible for screening. The test offers an alternative to low-dose CT imaging for patients meeting USPSTF criteria and is made available to health systems, primary care providers, and lung screening programs.
AI & Machine LearningBiotechDigital HealthHealthtechMedical Devices
iambic.ai develops an AI-driven platform for drug discovery that uses multimodal transformer and co-folding technologies to design novel molecules and optimize compounds for diseases. The company combines computational and experimental approaches to accelerate the development of first-in-class and best-in-class medicines.
AI & Machine LearningBiotechDeep Tech
Frequently asked questions
- What sectors does Illumina Ventures focus on?
- Illumina Ventures focuses on Biotech, Digital Health, Medical Devices.
- Where is Illumina Ventures located?
- Illumina Ventures is headquartered in Foster City, US.
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