PureTech Health
Venture studioBoston · 15 people tracked
Find your way into PureTech Health
1,404 people in our graph share verified history with the PureTech Health team — schools, employers, funds. One of them is your warm intro.
Investment thesis
PureTech Health builds and develops novel medicines by identifying patient needs where an existing therapeutic approach has demonstrated human efficacy but is held back by limitations such as off-target effects, low bioavailability, or poor tolerability. Its R&D model rests on three principles: validated efficacy, clear patient benefit, and an efficient, de-risked path to new classes of medicine. Programs are advanced through Founded Entities, exemplified by KarXT (Cobenfy) for schizophrenia, developed in Karuna Therapeutics and later acquired by Bristol Myers Squibb. Other programs include deupirfenidone for idiopathic pulmonary fibrosis and GlyphAllo, an oral allopregnanolone prodrug using its Glyph technology for mental health indications.
Source: firm website, verified Aug 7, 2026.
Team · 15 people
from the firm's website & curatedFounder mafia
The PureTech Health mafia →7 people who came through PureTech Health went on to found or lead other companies.
What they invest in
from 5 of 9 portfolio companiesBiotech ×4Healthtech ×3Medical Devices ×1Mental Health ×1
HQs:United States×4
Investments · 9 tracked
founders shown can be your intro pathBy year:2026 · 12024 · 12 dated
Adicet Bio develops allogeneic gamma delta CAR T cell therapies for patients with autoimmune diseases and cancer.
BiotechHealthtechMenlo Park, US
Aya Jakobovits(Executive Officer, Director)Nathan Hubbard(Executive Officer)inChen Schor(President, Chief Executive Officer and Director)
BoardJonathan Silverstein(Director)inCarl Gordon(Director)inFlorent Gros(Director)
Co-investorsForesite CapitalOrbiMedPontifax Venture CapitalQuan CapitalaMoonNovartis Venture Fund
Seaport Therapeutics develops therapeutics and medicines.
BiotechMental HealthBoston, US
Daphne Zohar(Founder, CEO and Board Member)inMichael Chen(Executive Officer)inLana Gladstein(Executive Officer)inAntony Loebel(Executive Officer)inEric Green(Executive Officer)in
BoardJames I. Healy(Director)
Co-investorsARCH Venture PartnersForesite CapitalHAWKTAILSofinnova VenturesThird Rock Ventures
Vor Biopharma is a biopharmaceutical company.
BiotechCambridge, US
Nathan Jorgensen(Executive Officer)Amy Mendel(Executive Officer)Robert Ang(Executive Officer, Director)Jean-Paul Kress(President, Chief Executive Officer and Chairman of the Board)
BoardKush Parmar(Director)inJoshua Resnick(Director)
Co-investors5AM VenturesOUP (Osage University Partners)RA Capital
Celea develops deupirfenidone, a pulmonary therapeutic targeting idiopathic pulmonary fibrosis in partnership with physicians and patient advocacy organizations.
BiotechHealthtechMedical Devices
Co-investorsRA CapitalLeaps by Bayer
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Akili Interactive LabsGallop OncologyKarunaKaruna Therapeutics
Exits · 3
IPOs and acquisitions across the tracked portfolioAdicet BioNASDAQ: ACETSeaport TherapeuticsNASDAQ: SPTXVor BiopharmaNASDAQ: VOR
Portfolio news
latest coverage across their companiesVor Biopharma · defenseworld.net · Sep 3, 2026
Adicet Bio · stocktitan.net · Aug 14, 2026

Celea Therapeutics · kalkine.co.uk · Aug 10, 2026
IPO stake values · per SEC filings · 2
Value of this firm's stake in each portfolio company at its IPO price, from the prospectus principal-stockholder table.
| Company | Owned | IPO price | At IPO | Stake value |
|---|---|---|---|---|
| Adicet Bio | 35.2% | $15.00 | Jan 2018 | $143.5M |
| Vor Biopharma | 9.0% | $18.00 | Feb 2021 | $57.7M |
Source: SEC S-1 / 424B prospectus filings. Stake value = shares beneficially owned × the initial public offering price, as disclosed — a market value at IPO, not a return multiple (the firm's original cost is not disclosed).
Frequently asked questions
- How many investments has PureTech Health made?
- PureTech Health has 5 tracked investments, 1 of which have exited via acquisition or IPO, including 1 dated in the last 24 months.
- What sectors does PureTech Health focus on?
- PureTech Health focuses on Biotech, Digital Health, Healthtech, Medical Devices.
- Where is PureTech Health located?
- PureTech Health is headquartered in Boston, US.
- Does PureTech Health lead rounds?
- PureTech Health typically participates in rounds rather than leading them.
- Who does PureTech Health co-invest with?
- PureTech Health most often shares deals with Sofinnova Ventures, ARCH Venture Partners, Foresite Capital, among 4 tracked co-investors.
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