Civilization Ventures Management, Llc
Venture capitalTiburon · Pre-Seed–Growth · 6 people tracked
Investment thesis
Civilization Ventures invests in life sciences and health innovation, focusing on genomics and diagnostics, digital health, and synthetic biology (including gene and cell therapies). The firm leads pre-seed and seed rounds, backing founders early and continuing to support them as they scale through an Opportunity Fund. Its track record includes companies that have reached public listings and notable acquisitions across gene therapy, molecular diagnostics, telemedicine, and single-cell analysis.
Source: firm website, verified Aug 3, 2026.
Team · 6 people
from the firm's website & public directories
What they invest in
from 57 of 67 portfolio companiesBiotech ×40Medical Devices ×24AI & Machine Learning ×22Healthtech ×20Digital Health ×17Deep Tech ×12SaaS ×6Wellness & Fitness ×3
HQs:United States×28United Kingdom×2Australia×1Italy×1
Investments · 67 tracked
founders shown can be your intro path
BillionToOne is a precision diagnostics company that uses molecular counting technology to develop non-invasive prenatal screening and liquid biopsy tests for early disease detection.
BiotechDigital HealthHealthtechMedical DevicesSan Francisco, US
Oguzhan Atay, PhD(Co-Founder, CEO, and Board Chair)David Tsao, PhD(Co-Founder, CTO, and Board Member)Oguzhan Atay(Founder)inDavid Tsao(Founder/CTO)inSukrit Silas(Cofounder)
Omada Health provides virtual-first, integrated care programs for chronic disease management, delivered as data-driven solutions for employers, health plans, and healthcare organizations.
Digital HealthHealthtechWellness & FitnessSan Francisco, US
Jonathan Root(Director)Casper De Clercq(Director)Andrew DiMichelle(Executive Officer, Director)Adrian James(Executive Officer, Director)Sean Duffy(Executive Officer, Director)Balaji Srinivasan(Director)
Oxford Cancer Analytics develops a diagnostic platform that combines proteomic measurement with AI to generate evidence-based clinical insights for lung disease management, initially focused on COPD and lung cancer.
AI & Machine LearningDigital HealthMedical DevicesOxford, GB
23andMe operates a research platform that collects genetic data from millions of users to advance genomic research and health discovery.
BiotechDigital HealthDirect to ConsumerHealthtechLongevityMountain View, US
Anne Wojcicki(Co-founder & CEO)Linda Avey(Co-founder)Paul Cheung(Co-founder)Andrew Page(Executive Officer, Director)Esther Dyson(Director)Kathy Hibbs(Executive Officer)
Adyn uses large inclusive datasets and machine learning to advance personalized medicine for historically under-researched health conditions, with initial focus on reproductive disorders.
AI & Machine LearningDigital HealthHealthtechMedical DevicesWellness & FitnessSeattle, US
Elizabeth Ruzzo(Founder, CEO)
Alveo Technologies develops a portable molecular testing platform that delivers rapid pathogen detection in under one hour at the point of need, with initial focus on avian influenza testing for poultry farms and agricultural operations.
AgTechBiotechHealthtechMedical Devices<UNKNOWN>
Isaac Blech(Director)Robin Steele(Director)Michael Aicher(Executive Officer, Director)Ron Chiarello(Executive Officer, Director)Lawrence Blatt(Director)
Antheia manufactures biosynthetic active pharmaceutical ingredients and key starting materials for essential medicines using advanced fermentation-based biosynthesis, replacing traditional agricultural sourcing to improve pharmaceutical supply chain reliability.
Advanced ManufacturingBiotechMedical DevicesMenlo Park, US
Ram Shriram(Director)Catherine Thodey(Director)Christina D. Smolke(Executive Officer, Director)
Aperiam Bio uses computational methods to identify stabilizing mutations in proteins, producing variants with improved expression, solubility, and activity for applications in technical reagents, cosmetics, and pulmonary therapeutics.
AI & Machine LearningBiotechDeep TechAustin, US
Austin Cole(Executive Officer, Director)
Aspect Bio Systems develops bioprinted tissue therapeutics for regenerative medicine using a platform that combines AI-powered bioprinting, computational design, therapeutic cells, and biomaterials.
AI & Machine LearningBiotechDeep Tech
Axonis Therapeutics develops medicines targeting KCC2 to restore inhibition in the brain, with a focus on treating neurological disorders including epilepsy and pain.
BiotechMedical DevicesBoston, US
Shane Hegarty(Executive Officer)Jeffrey Imbaro(Executive Officer)Joanna Stanicka(Executive Officer, Director)
BoardCorey . Goodman(Director)Jonathan Leff(Director)Raymond J. Kelleher(Director)
Babyscripts provides remote patient monitoring and care management software for obstetric teams to identify maternal health risks during pregnancy and postpartum, serving health systems, private practices, and payers.
Digital HealthFemTechHealthtech
Biomemory develops DNA-based data storage systems for data centers, offering an alternative storage tier optimized for long-term archival, density, and energy efficiency.
Climate TechData & InfrastructureDeep Tech
Catena develops a conjugation platform for antibody-drug conjugates (ADCs) and multi-payload conjugates used in oncology for solid tumors.
BiotechDeep TechHealthtechMedical DevicesSan Francisco, US
Convergent Genomics develops UroAmp, a non-invasive genomic urine test for detecting and monitoring bladder cancer using liquid biopsy and next-generation sequencing technology.
BiotechDigital HealthMedical Devices
Fierce Biotech is a news publication covering the biotechnology, pharmaceutical, and medtech industries, reporting on clinical trials, deals, venture capital, drug development, and research.
BiotechMedia & Entertainment
Curai Health provides virtual medical care through a team of doctors and healthcare experts for diagnosis and treatment of various conditions, available with or without insurance.
Digital HealthHealthtech
Delineate builds AI agents that help pharmaceutical companies design clinical trials more quickly by converting existing trial research into specialized datasets, reducing the time scientists spend on trial preparation.
AI & Machine LearningBiotechDeveloper ToolsEnterprise SoftwareSaaSBoston, US
DermBiont develops SM-030, a topical drug candidate targeting melasma, a skin pigmentation disorder, by inhibiting PKC-beta to address the underlying cause of hyperpigmentation.
BiotechDigital HealthMedical DevicesBoston, US
Karl R. Beutner(Executive Officer, Director)Nichola Eliovits(Executive Officer, Director)Max Dawson(Executive Officer)Jennifer Lee(Director)Robert Brucker(Executive Officer)
BoardWilder Ramsey(Director)
Fluent Bio develops software for analyzing single-cell RNA sequencing data, producing count matrices and diagnostic outputs for researchers using Illumina sequencing libraries.
BiotechDeveloper Tools
Cancer recurrence testing platform acquired by Natera.
Foresight Diagnostics develops ultra-sensitive diagnostic tests using genomics and bioinformatics to detect minimal residual disease in cancer patients, serving clinical and biopharma partners in oncology drug development and patient care.
AI & Machine LearningBiotechMedical Devices<UNKNOWN>
Glyphic Biotechnologies develops ProSE™, a high-throughput de novo protein sequencing technology for analyzing proteomes with single-molecule sensitivity.
BiotechDeep TechBerkeley, US
Joshua Yang(Founder & CEO)Daniel Estandian(Founder)Ed Boyden(Founder)Craig Asher(Director)Jimmy Yun(Director)
Iantrek develops medical devices and technologies for micro-interventional ophthalmic surgery, specifically targeting glaucoma treatment through uveoscleral pathway outflow enhancement for surgeons and ophthalmologists.
BiotechMedical DevicesElkins Park, US
Tsontcho Ianchulev(Executive Officer, Director)Michael Haydin(Executive Officer)Andrew Corley(Director)Stephen Bloch(Director)
BoardJeffry K Weinhuff(Director)Farrell Tyson(Director)
Infinimmune discovers and develops antibody therapeutics using proprietary sequencing technology and AI-powered optimization.
AI & Machine LearningBiotechMedical Devices
Insamo develops an automated platform for drug discovery that designs, synthesizes, and tests cyclic peptides at scale using machine learning and proprietary experimental data.
AI & Machine LearningBiotechDeep TechChippendale, AU
Tim Craven(CEO)Toby Passioura(CSO)Glen McIntyre(COO)COREY GOODMAN(Director)TIMOTHY CRAVEN(Executive Officer, Director)MATT HERSHENSON(Director)
Integrated Biosciences develops a platform for small molecule drug discovery targeting age-related diseases by combining optogenetics, chemistry, and AI to probe disease biology with precision and explore chemical space systematically.
AI & Machine LearningBiotechLongevityRedwood City, US
Felix Wong(Executive Officer, Director)Keith Loebner(Director)Themasap Khan(Director)
Invitae provides genetic testing services to patients and clinicians across the United States, offering broad test offerings and genetic counseling to inform health decisions at every stage of life.
BiotechDigital HealthHealthtechMedical DevicesSan Francisco, US
Shelly Guyer(Executive Officer)Eric Aguiar(Director)Sean George(Executive Officer, Director)Christine Gorjanc(Director)Geoffrey Crouse(Director)Lee Bendekgey(Executive Officer)
Kernal Bio is a synthetic biology company developing selective mRNA drugs to treat serious illnesses, with a focus on cancer therapeutics and improving patient outcomes.
AI & Machine LearningBiotechHealthtechMedical DevicesBoston, US
Yusuf Erkul(Founder)inJeff Ozdemir(Founder)inBurak Yilmaz(Founder)inBurak YILMAZ(Founder)inCatherine Moroski(Executive Officer, Director)Oguzhan Yilmas(Director)
Telemedicine pioneer acquired by 23andme for $400M.
Manus develops and manufactures bioalternatives—sustainable ingredients produced using engineered microbes and cell factories—for use in food, flavor, fragrance, and other consumer products.
BiotechCleantechAugusta, US
Richard Goldstein(Director)Jason Whaley(Director)Carsten Boers(Director)Ajikumar Parayil(Executive Officer, Director)Gregory Stephanopoulos(Director)
Outpace Bio develops engineered protein technologies and cell therapies to treat solid tumors, focusing on protein design and T cell engineering to improve cancer treatment efficacy and safety.
BiotechDeep TechMedical DevicesSeattle, US
Marc Lajoie(Co-founder & Chief Executive Officer)Scott Boyken(Co-founder & Chief Technology Officer)Stanley Riddell(Co-Founder and Scientific Advisor)Aaron Foster(Executive Officer)Charity Scripture(Executive Officer)Eric Soller(Executive Officer)
Overt Bio develops cell therapies that link genes to immune functions using genome-scale discovery platforms.
AI & Machine LearningBiotechMedical DevicesNew York, US
Dr. Legut(Co-Founder and CEO)Dr. Sanjana(Co-Founder)Mateusz Legut(Executive Officer, Director)Vasudev Bailey(Director)Sara Choi(Director)Neville Sanjana(Director)
Cision PRWeb is a press release distribution and publicity platform that helps organizations communicate with target audiences through search, social media, and industry-specific partner networks including bloggers and influencers.
Marketing TechSaaS
Prellis develops an AI-enabled platform for antibody discovery using 3D-printed organoids that recapture human immune biology, generating therapeutic antibody candidates for multiple disease areas.
AI & Machine LearningBiotechDeep TechHayward, US
Arvind Gupta(Director)Melanie Matheu(Executive Officer, Director)Noelle Mullin(Executive Officer, Director)Rohit Sharma(Director)
QUiCKR develops rapid genetic modification quantification kits for cell and gene therapy R&D programs, analyzing structural variants, edits, and genome integrity to accelerate development timelines and reduce costs.
BiotechDeep TechMedical Devices
Range Bio develops next-generation diagnostic tools using translational proteomics for clinical and research applications in human health.
BiotechDigital HealthMedical Devices
Brandon Wilson, Ph.D.(Co-founder & CEO)
Gene editing pioneer and founding investment acquired by Intellia for $200M.
Gene editing company, with Civilization as founding investor, acquired by Intellia for $200M.
Rocket Pharmaceuticals develops gene therapies to treat patients with rare genetic diseases, focusing on cardiovascular and hematologic disorders.
BiotechDigital HealthMedical Devices
Gaurav Shah(Co-founder & Chief Executive Officer)Roderick Wong(Director)Naveen Yalamanchi(Director)
R-Zero provides AI software that reduces HVAC energy consumption in buildings by 20-40% using real-time occupancy and air quality data, with no infrastructure changes required.
CleantechEnterprise SoftwareIoTUnknown, US
Sensible Biotechnologies develops a cell-based mRNA design and manufacturing platform that produces pure, low immunogenicity mRNA therapeutics for drug development.
AI & Machine LearningBiotechDeep TechHealthtechOxford, GB
Genetic screening platform for early pregnancy, acquired by Invitae.
HealthtechSan Francisco, US
Eli Casdin(Director)Jones Hywel(Executive Officer, Director)
Siren Biotechnology develops next-generation AAV (adeno-associated virus) platforms for gene therapy applications, including gene repair, gene transfer, and gene editing.
BiotechDigital HealthMedical DevicesSan Francisco, US
Dr. Nicole Paulk(CEO, Founder, and President)Sharon Tetlow(Director)Brad Allen(Director)Nicole Paulk(Executive Officer, Director)
Teiko provides multi-parameter cytometry services for clinical trials, including blood preservation kits (TokuKit), spectral and mass cytometry panels, and data analysis via its Dashboard platform.
BiotechDigital HealthMedical DevicesSalt Lake City, US
Ramji Srinivasan(Executive Officer, Director)inMatthew Spitzer(Director)
BoardVictor Wang(Director)
TenSixty uses machine learning and cell biology expertise to identify novel antibody targets on cancer cells for the development of new cancer therapeutics.
AI & Machine LearningBiotechMedical Devices
Christoph Muus(Director)Dipchand Nishar(Director)Daniel Montoro(Executive Officer, Director)Karthik Jagadeesh(Executive Officer, Director)Sara Choi(Director)
Frequently asked questions
- What stage does Civilization Ventures Management, Llc invest at?
- Civilization Ventures Management, Llc invests at the Pre-Seed, Seed, Growth stages.
- What is Civilization Ventures Management, Llc's typical check size?
- Civilization Ventures Management, Llc typically writes checks of $1M – $10M.
- What sectors does Civilization Ventures Management, Llc focus on?
- Civilization Ventures Management, Llc focuses on AI & Machine Learning, Biotech, Digital Health, Healthtech, Longevity, Medical Devices.
- Where is Civilization Ventures Management, Llc located?
- Civilization Ventures Management, Llc is headquartered in Tiburon, US.
- Does Civilization Ventures Management, Llc lead rounds?
- Yes, Civilization Ventures Management, Llc leads investment rounds.
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Co-investors · 3
Lookout Ventures provides seed-stage funding to enterprise technology companies outside Silicon Valley, with partner expertise in AI, cybersecurity, infrastructure software, and vertical SaaS.
Antler is an early-stage venture capital firm operating across major technology ecosystems worldwide, backing entrepreneurs from company formation onward and supporting a large global portfolio of startups, including many AI companies.
Foresite Capital is a multi-stage investment firm focused on healthcare and life sciences, backing companies across all stages of growth. It applies a data science-driven approach to invest in businesses leveraging biology and big data to transform healthcare.
Firms observed investing alongside Civilization Ventures Management, Llc, from public investor directories. Shared companies are the overlap with Civilization Ventures Management, Llc's recorded portfolio.
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