Catalio Capital Management
New York · 2 people tracked
Not to be confused with Catalio Capital Management, LP (Crossover fund · New York, US)
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Investment thesis
Catalio is a software platform that uses AI to automatically extract and document business logic from legacy and modern systems, creating living specifications that stay current as software evolves.
Source: firm website, verified Aug 6, 2026.
Team · 2 people
from public directoriesWhat they invest in
from 44 of 46 portfolio companiesBiotech ×32Healthtech ×23Medical Devices ×14AI & Machine Learning ×13Digital Health ×10Deep Tech ×7Advanced Manufacturing ×2Consumer ×2
HQs:United States×32Switzerland×1United Kingdom×1Singapore×1
Investments · 46 tracked
founders shown can be your intro pathBy year:2026 · 62025 · 82024 · 42023 · 62022 · 72021 · 42020 · 136 dated
Avalyn Pharma develops inhaled therapies for pulmonary fibrosis, using a nebulization approach that delivers treatment directly to the lungs to reduce the tolerability problems of existing oral therapies.
BiotechHealthtech
Lyn Baranowski(CEO)in
Co-investorsAndera PartnersCatalio Capital Management, LPF-Prime CapitalInVivium CapitalNorwest Venture PartnersPivotal Life Sciences+9 more
Neumora is a clinical research company developing investigational medications, with a focus on conducting clinical trials to obtain regulatory approval and make treatments available to patients.
BiotechDeep TechDigital HealthMedical DevicesWatertown, US
Paul L. Berns(Chairman and Chief Executive Officer)Joshua Pinto(Executive Officer)Tamara Tompkins(Executive Officer)inKari Stefansson(Director)Maykin Ho(Director)Alaa Halawa(Director)
Co-investorsARCH Venture PartnersCatalio Capital Management, LPF-Prime CapitalK2 HealthVenturesMercury FundPremier Partners+12 more
Alentis is a biotech company developing therapies for chronic liver disease, fibrosis, and cancer based on the molecular biology of liver disease.
AI & Machine LearningBiotechHealthtechMedical DevicesBasel, CH
Thomas Baumert(Founder)inMark Pruzanski(Chief Executive Officer)inLuigi Manenti(Chief Medical Officer)inJon Freve(Chief Financial Officer)inBryan Yoon(General Counsel and Chief Administrative Officer)inAditya Venugopal(Chief Business Officer)in
Co-investorsAvego BioScience CapitalBioMedPartnersFrazier Life SciencesJeito CapitalLongitude CapitalNovo Holdings+5 more
Iambic develops AI technologies for drug discovery, using a high-throughput experimental platform to design small-molecule medicines and advance a pipeline of clinical candidates for cancers such as HER2-driven, breast, and ovarian tumors.
AI & Machine LearningBiotechDeep TechSan Diego, US
Tom Miller(Founder)inFred Manby(Founder)inChao Zhang(Executive Officer)inTabbert Teng(Executive Officer)Neil Josephson(Chief Medical Officer)inPete Olson(Chief Scientific Officer)in
Co-investorsAscenta CapitalAbingworthAlumni VenturesCatalio Capital Management, LPCoatue ManagementEisai Innovation, Inc.+7 more
Orasis is a pharmaceutical company developing drugs for the eye, operating in the ophthalmology and eyecare space.
BiotechHealthtechMedical Devices
Co-investorsArboretum VenturesMaverick Ventures IsraelVisionary VenturesJohnson & Johnson Innovation – JJDCLifeSci Venture PartnersSequoia Capital+1 more
Spiral Therapeutics is a clinical-stage pharmaceutical company developing therapies for balance disorders and hearing loss using its Minimally Invasive Cochlear System (MICS) drug delivery platform.
BiotechDigital HealthHealthtechMedical DevicesSouth San Francisco, US
Hugo Peris(Founder & CEO)inEugene de Juan(Executive Officer, Director)Lawrence Fritz(Director)
BoardWARREN THALER(Director)JEAN-FREDERIC PAULSEN(Director)Guy Nohra(Director)in
Co-investorsInveready Technology Investment GroupLifelinkStartXAlta PartnersCamden PartnersEsperante Ventures
Nicolas Tilmans(Founder)
Co-investorsAir Street CapitalLux Capital
Cartography develops antibody-based cancer therapies using single-cell sequencing and computational biology to identify precise cellular targets.
AI & Machine LearningBiotechDeep TechMedical DevicesSouth San Francisco, US
Max Mumbach(Founding Scientist, Target Discovery)inJeffrey Verboon(Founding Scientist, Computational Biology)inAnsu Satpathy(Founder)Kevin Parker, PhD(Chief Executive Officer, Board Director; co-founder)Ansuman Satpathy, MD, PhD(Co-founder; Board Director)Howard Chang(Founder)in
Co-investors8VCAndreessen HorowitzArtis VenturesCatalio Capital Management, LPFinchley Healthcare VenturesGlobal BioAccess Fund+9 more
Character Bio is a patient-driven therapeutics company that combines genomics, longitudinal clinical and imaging data, and machine learning to identify genetic drivers of disease progression and develop new treatments, with a focus on polygenic diseases.
AI & Machine LearningBiotechDigital HealthJersey City, US
Cheng Zhang(CEO, Co-Founder)inMarcel van der Brug(Scientific Advisor, Co-Founder)inNick Johnson(Technology Advisor, Co-Founder)inDaniel Elgort(Chief Data and Analytics Officer)inLaura Carter(Chief Scientific Officer)inRobert Kim(Chief Medical Officer)in
Co-investorsaMoonLuma GroupSanofi VenturesInnovation EndeavorsCantos VenturesCatalio Capital Management, LP+5 more
Claris Bio develops biologic therapies for sight-threatening eye diseases, with a current focus on bringing CSB-001, a novel treatment for patients with limbal stem cell deficiency, through clinical development and to market.
BiotechHealthtechMedical DevicesJersey City, US
Clarke Atwell(Co-Founder and Chief Operating Officer)inHenry Rath(Executive Officer)Susan Orr(Executive Officer)inStephen Brady(Executive Officer, Director)Michael Dybbs(Director)Matt Hobson(Director)
Co-investorsCatalio Capital Management, LPRA CapitalSofinnova VenturesNovo HoldingsSamsara BioCapital
Clasp Therapeutics develops off-the-shelf precision T cell engagers (its proprietary pHLАre molecules) that target mutant peptide-HLA complexes displayed on cancer cells, directing T cells to destroy tumors carrying common driver mutations such as KRas.
BiotechHealthtechCambridge, US
Co-investorsCatalio Capital Management, LPCure VenturesVivo CapitalBrightEdgeNovo HoldingsThird Rock Ventures
Cortex Robot builds datasets for embodied AI and robotics, including egocentric video data from real workplaces and robot trajectories for training physical intelligence systems.
Advanced ManufacturingAI & Machine LearningData & InfrastructureRoboticsSan Francisco, US
Lucas Ngoo(Founder)in
Co-investorsPioneerTranspose Platform ManagementY Combinator468 Capital500 GlobalBlast.Club+14 more
Biotechnology company using multiplex gene editing to develop genetically engineered porcine organs for human transplantation.
BiotechBrookline, US
Luhan Yang(President, Secretary and Treasurer)Geoff MacKay(Chief Executive Officer)
BoardGeorge M. Church(Director)
Co-investorsAlta PartnersARCH Venture PartnersCatalio Capital Management, LPHBM Healthcare InvestmentsHBM PartnersKhosla Ventures+12 more
Ensoma is a genomic medicine company developing a platform for in vivo engineering of hematopoietic stem cells (HSCs), combining an off-the-shelf delivery system with a gene engineering toolkit intended to treat diseases with a one-time treatment.
BiotechHealthtechMedical DevicesBoston, US
Albert Seymour(Director)
BoardKush Parmar(Executive Officer, Director)inPaula Soteropoulos(Director)Stephen Knight(Director)in
Co-investors5AM VenturesAju IB InvestmentCatalio Capital Management, LPDelos CapitalF-Prime CapitalSolasta Ventures+10 more
Enveda operates a drug-discovery platform that analyzes natural samples—primarily plant-derived molecules—using mass spectrometry, AI foundation models, and automated high-throughput labs to identify their chemical structures and therapeutic properties.
AI & Machine LearningBiotechDeep TechBoulder, US
Viswa Colluru(Founder)inDaniel Wee(Executive Officer)Pieter Dorrestein(Founder)Viswa Colluru Pieter Dorrestein(Founder)
BoardRohit Sharma(Director)Zavain Dar(Director)in
Co-investorsAir Street CapitalBoulder VenturesCatalio Capital Management, LPCox EnterprisesFPVHummingbird Ventures+20 more
Evvy is an AI-powered precision medicine platform using vaginal microbiome testing and analysis to diagnose and treat women's health conditions including vaginal health, fertility, and menopause.
AI & Machine LearningDigital HealthFemTechHealthtech
Priyanka Jain(Founder)inLaine Bruzek(Founder)inPita Navarro(Founder)in
Co-investorsAlumni VenturesAmboy Street VenturesBoxGroupForeground CapitalForerunner VenturesGeneral Catalyst+9 more
Extracellular is a biomanufacturing company that helps cell-based product developers in cultivated meat, plant cell culture, and bioactives accelerate discovery, overcome production challenges, and commercialize their products.
Advanced ManufacturingBiotechFoodTechNew Materials
Will Milligan(CEO & Founder)in
Co-investorsBig Idea VenturesFFFNewland SyndicateUnruly Capital5AM VenturesAgent Capital+8 more
Georgiamune is a biopharmaceutical company developing targeted immunomodulator drugs that activate or down-modulate immune signaling pathways to treat cancer and autoimmune diseases.
BiotechDeep TechHealthtechGaithersburg, US
Samir N. Khleif(Founder & CEO)inRamy Ibrahim(Chief Medical and Strategy Officer)inMikayel Mkrichyan(Senior Vice President of Science and Discovery)Sarah Sharman(Vice President of IP Legal Affairs)
BoardSean Parker(Director)Elena Viboch(Director)in
Co-investorsCatalio Capital Management, LPGeneral CatalystHAWKTAILLauder PartnersPrevail Venture CapitalAlexandria+3 more
Cambridge, MA biotechnology company developing injectable synthetic biomarkers for noninvasive disease staging and treatment monitoring.
BiotechCambridge, US
Gabriel Kwong(Executive Officer)inSangeeta BhatiainRoopom Banerjee(Executive Officer)in
BoardTheresia Gouw(Director)inAmy Schulman(Director)Stan Lapidus(Director)in
Co-investorsGreatPoint VenturesAcrew CapitalARCH Venture PartnersAspect VenturesCRV (Charles River Ventures)Dns Capital+7 more
Imbria Pharmaceuticals develops novel cardiovascular disease treatments that target cardiac energy metabolism, with a lead drug candidate, ninerafaxstat, in clinical trials for non-obstructive hypertrophic cardiomyopathy.
BiotechDigital Health
Alvin Shih(CEO)inAlbert M. Kim(Chief Medical Officer)in
Co-investorsAN Venture PartnersCatalio Capital Management, LPRA CapitalSanofi VenturesSV Health Investors
Chronus is a platform that connects employees for guided, AI-assisted conversations focused on career development, mentoring, community building, and change adoption in enterprise organizations.
AI & Machine LearningEnterprise SoftwareFuture of WorkHR TechSaaSNew York, US
Aaron Hurst(Founder)in
Co-investorsEmpire AngelsVoyager CapitalAlly Bridge GroupAmed VenturesAscension VenturesBain Capital Life Sciences+4 more
Insightec develops Exablate Neuro, an MRI-guided focused ultrasound platform that treats Essential Tremor and tremor-dominant Parkinson's Disease through an incision-free outpatient procedure.
HealthtechMedical DevicesTirat Carmel
Roni Karie(Vice President - Finance)Shirel Aroshase(Vice President - Human Resources)inEyal Zadicario(General Manager)inMenashe Frank(Vice President - Legal)inJun (Jim) Tao(Chief Operating Officer)inMaurice R. Ferre(Chairman and Chief Executive Officer)in
Co-investorsCatalio Capital Management, LPExigent CapitalGEOCJazzya InvestmentsKoch Disruptive TechnologiesKrillion Ventures+6 more
Lassen Therapeutics is a biotechnology company developing therapeutics targeting IL-11, with a pipeline focused on immune and fibrotic diseases.
Biotech
David King(Co-Founder & CSO)inMaria Fardis(CEO)inCadmus C. Rich(Chief Medical Officer)inElaine Stracker(General Counsel)in
Co-investorsAlta PartnersCatalio Capital Management, LPDC Investment PartnersFrazier Life SciencesLongitude CapitalLongwood Fund+2 more
Leo Capital is a venture capital firm founded by operators with experience building and scaling category-defining companies, investing across continents with a focus on India and global markets.
AI & Machine LearningEnterprise SoftwareFintechSingapore, SG
Rajul Garg(Founder & Managing Partner)inShwetank Verma(Co-founder & Managing Partner)in
Co-investorsInterplay Ventures Early Stage Management LlcJetty VenturesTesi (Finnish Industry Investment Ltd)Flint CapitalYu Galaxy
Leo Cancer Care develops upright radiotherapy and particle therapy solutions that integrate CT imaging with patient positioning systems.
Deep TechHardwareHealthtechMedical Devices
Stephen Towe(Founder)in
Co-investorsCatalio Capital Management, LPDevice of Tomorrow CapitalSerra VenturesStar51 CapitalYu GalaxyMana Ventures
Muse Capital is an early-stage venture capital firm that invests in consumer technology companies focused on how people care, play, and live.
AI & Machine LearningConsumerDigital Health
Rachel SpringateinAssia Grazioli-Venierin
Co-investorsDarco CapitalAlumni VenturesGeneral CatalystRethink Impact
NextPoint is a precision therapeutics company developing cancer treatments targeting the B7-H7/HHLA2 axis, including a T-cell engager, an antibody-drug conjugate with proprietary linker technology, and a multi-functional checkpoint inhibitor.
BiotechHealthtechAustin, US
Gordon Freeman(Scientific Founder)XingXing Zang(Scientific Founder)inIvan Cheung(Chief Executive Officer)inLeena Gandhi(Chief Medical Officer)inTatiana Novobrantseva(Chief Scientific Officer)inAxel Hoos(Director)
Co-investorsCatalio Capital Management, LPMPM BioImpactSanofi VenturesInvusLeaps by BayerSixty Degree Capital
Noetik builds AI models to identify cancer patients most likely to respond to treatments and to discover new oncology drug targets.
AI & Machine LearningBiotechHealthtechSouth San Francisco, US
Jacob Rinaldi(Founder)inRonald Alfa(Executive Officer, Director, Promoter)Ron Alfa, MD, PhD(Co-Founder, CEO)inRon Alfa(Founder)Ron Alfa Jacob Rinaldi(Founder)
BoardJames Hardiman(Director)in
Co-investors11.2 CapitalBreakout LabsBreakout VenturesCatalio Capital Management, LPEPIC VENTURESIntermountain Health+6 more
Octant is a therapeutics company that develops small molecule drugs to treat protein misfolding diseases.
AI & Machine LearningBiotechDeep TechMedical DevicesEmeryville, US
Sri Kosuri(Founder)inRamsey Homsany(Founder)inRobert Andrade(Executive Officer, Director, Promoter)Maurice J. Costantini(Executive Officer, Director, Promoter)
Co-investorsAndreessen Horowitz+ND Capital8VCCarbon SiliconCatalio Capital Management, LPExplorer Investments+9 more
Pheast Therapeutics develops immunotherapies targeting cancer, building on foundational research from Stanford's stem cell research institute.
BiotechHealthtechMedical DevicesRedwood City, US
Irv Weissman(Cofounder, Scientific Advisor, Board Director)Ravi Majeti(Cofounder, Scientific Advisor, Board Observer)Amira Barkal(Principal Founder, Scientific Advisor, Board Director)inRoy Maute(Cofounder & Chief Executive Officer)in
BoardJacob Vogelstein(Director)Steven Gillis(Director)in
Co-investorsARCH Venture PartnersCatalio Capital Management, LPAlexandria
ProSomnus offers oral appliance devices for treating obstructive sleep apnea and snoring, positioned as an alternative to CPAP machines.
Digital HealthHealthtechMedical DevicesWellness & FitnessPleasanton, US
Leonard Liptak(Executive Officer, Director)Sung Kim(Executive Officer)Jason Orchard(Director)Steven Pacelli(Director)Heather Rider(Director)Laing Rikkers(Executive Officer, Director)
Co-investorsCatalio Capital Management, LPSpring Mountain Capital
Ratio Therapeutics develops radiopharmaceuticals for oncology, working on targeted radiochemistry, discovery, and preclinical and clinical development.
BiotechHealthtechMedical DevicesBoston, US
John Babich(Director, President & Chief Scientific Officer)inJack Hoppin(Chairman & Chief Executive Officer)inJack Hoppin, Ph.D.(Chairman, Chief Executive Officer)William Cupelo(Chief Business Officer)Matthias Friebe(Chief Technology Officer)inScott Holbrook(Chief Commercial and Manufacturing Officer)in
Rhapsogen is developing a precision biologic therapy aimed at treating autoimmune diseases, focused on efficacy, safety, and durability.
BiotechHealthtech
Co-investorsCatalio Capital Management, LP
HealthtechCambridge, US
Rahul Dhanda(Executive Officer, Director)inJames Collins(Director)David Walt(Director)in
BoardIssi Rozen(Director)in
Co-investorsCatalio Capital Management, LPIllumina VenturesGood VenturesGV (Google Ventures)Northpond VenturesNovalis LifeSciences
Somethings connects teenagers with peer mentorship support to address gaps in mental health access in the United States.
Digital HealthHealthtechMental HealthWellness & Fitness
Patrick Gilligan(Founder)in
Co-investorsCatalio Capital Management, LPCoalition OperatorsGeneral CatalystMana VenturesTau VenturesBehind Genius Ventures+4 more
Star Therapeutics develops treatments aimed at addressing real-world patient needs.
BiotechSouth San Francisco, US
Adam Rosenthal(Founder & CEO)inNancy Stagliano(Director)inMichelle Carpenter(Executive Officer)Sandip Panicker(Executive Officer)Scott Robertson(Executive Officer)inGary Patou(Executive Officer)in
Co-investorsFrazier Life SciencesOrbiMedRA CapitalSanofi VenturesSofinnova VenturesViking Global+11 more
Syndeio Biosciences is a synapse-focused biotech developing precision neurotherapeutics for neuropsychiatric, mental health, and cognitive disorders such as depression and Alzheimer's.
AI & Machine LearningBiotechDigital Health
Co-investorsEvolution VC PartnersPalo Santo VCTenmile
Visby offers an FDA-authorized at-home PCR test kit for women's sexual health that detects chlamydia, gonorrhea, and trichomoniasis from a single swab, delivering private results via a mobile app in about 30 minutes with included same-day telehealth for positive results.
ConsumerDigital HealthFemTechHealthtechMedical DevicesTokyo, US
Adam de la Zerda(Founder)in
Co-investors+ND Capital1809 CapitalAmplify PartnersArtiman VenturesG Vision CapitalJ-Ventures+6 more
Volastra Therapeutics is a drug discovery and development company working on novel cancer therapies.
BiotechHealthtechNew York, US
Samuel Bakhoum(Co-Founder & Chief Scientific Officer)inLewis Cantley(Founder and Chair of Scientific Advisory Committee)Olivier Elemento(Founder and Scientific Advisor)David P. Southwell(Chief Executive Officer)in
BoardRobert Mittendorff(Director)inJill Goldstein(Director)in
Co-investorsDroia VenturesARCH Venture PartnersB Capital GroupB4 CapitalVida VenturesPolaris Partners
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
AvavaHaystack OncologyImbria PharmaceuticalsManaT BioPerceive BiotherapeuticsSensei BiotherapeuticsXilis, Inc.
Exits · 3
2 IPOs · 1 acquisitions · showing 2Avalyn Pharma IncNASDAQ: AVLNNeumora TherapeuticsNASDAQ: NMRA
Portfolio news
latest coverage across their companiesEvvy · citybiz.co · Sep 16, 2026
Ratio Therapeutics · finsmes.com · Aug 3, 2026
Enveda Biosciences · enveda.com · Jul 8, 2026
Cartography Biosciences · finsmes.com · May 7, 2026
Spiral Therapeutics · finsmes.com · Apr 14, 2026
ProSomnus · finsmes.com · Feb 19, 2026
Somethings · prnewswire.com · Feb 10, 2026
Frequently asked questions
- How many investments has Catalio Capital Management made?
- Catalio Capital Management has 46 tracked investments, 3 of which have exited, including 14 dated in the last 24 months.
- What sectors does Catalio Capital Management focus on?
- Catalio Capital Management focuses on Developer Tools, Enterprise Software.
- Where is Catalio Capital Management located?
- Catalio Capital Management is headquartered in New York, US.
Images
Co-investors · 12
Catalio is a New York-based investment firm focused on innovative healthcare, investing across the full lifecycle through private, public, and credit markets.
ARCH Venture Partners is a venture capital firm that invests in and helps build transformational companies, with a strong focus on the life sciences and biotechnology sector.
Andreessen Horowitz (a16z) is a venture capital firm founded in 2009 by Marc Andreessen and Ben Horowitz, known for pioneering the platform model with a large team of operators supporting founders across stages.
Third Rock Ventures is a venture capital firm that discovers, launches, and builds life sciences and biotechnology companies developing novel medicines and therapies.
Vivo Capital is a global healthcare-focused investment firm operating a multi-strategy platform spanning venture capital, private equity, and public equity. It aims to expand healthcare access and drive innovation through its 'Ecosystem Strategy.'
Illumina Ventures is a venture investor focused on genomics and precision health, aiming to advance innovation and impact in human health.
EQT Life Sciences (formerly LSP) is one of Europe's largest and most experienced life sciences investors, backing companies developing therapeutics, medical devices, diagnostics and healthtech globally.
Dimension is a multistage investment firm that partners with companies working at the intersection of science and compute.
Inveready is a Spanish alternative investment firm founded in 2008, offering investment solutions and wealth management services across the small and mid-market segment in Spain.
What If Ventures is a venture capital firm investing in transformative technology, with a focus on healthcare/mental health and defense technology.
Presight Capital is a venture capital firm that invests across stages in science- and technology-driven companies, including biotech, mental health therapeutics, fusion energy, robotics, and healthcare.
Kurma Partners is a European healthcare-focused investment firm that co-founds and finances biotech and healthcare companies, working closely with research centers to translate scientific discoveries into high-tech companies.
Firms observed investing alongside Catalio Capital Management, from public investor directories. Shared companies are the overlap with Catalio Capital Management's recorded portfolio.
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