Fundraising Fox
Sixty Degree Capital
Venture capitalNorth York · Pre-Seed–Growth · 17 people tracked
Also known as Sixty Degree
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Investment thesis
Sixty Degree Capital invests across healthcare and technology, backing breakthrough opportunities with potential to reshape industries. The firm employs a thesis-driven investment process in which a technical team combines domain expertise, rigorous analysis, and hands-on operational support to identify durable, transformational change. On the healthcare side it targets biotechnology, drug development, diagnostics, digital health, and medical devices; on the technology side it focuses on AI, cybersecurity, digital infrastructure, developer tools, cloud, and SaaS. The firm invests from pre-seed through growth stages and supports founders globally, and dedicates a portion of proceeds to educational institutions, hospitals, and community organizations as part of its giving-back philosophy.
Source: firm website, verified Sep 27, 2026.
Team · 17 people
from the firm's website & curated
What they invest in
from 31 of 41 portfolio companiesHealthtech ×16Biotech ×14AI & Machine Learning ×12Enterprise Software ×9Digital Health ×5Cloud Computing ×4Cybersecurity ×4Data & Infrastructure ×4
HQs:United States×21Germany×2United Kingdom×1Israel×1
Who they back
founder profiles across 13 portfolio companiesFounding team size:solo founder×52 founders×33 founders×5
What their founders studiedfrom 10 founders with field-of-study data
Computer Science ×2Engineering ×2Life Sciences ×2Mathematics & Statistics ×2
Where their founders worked beforefrom 15 founders with career history
Vectura Group plc. ×2
Investments · 41 tracked
founders shown can be your intro pathBy year:2026 · 22025 · 22024 · 22023 · 12022 · 22021 · 32020 · 214 dated
Cyber Fund III portfolio company that completed an initial public offering.
Herndon, US
Christopher Bradley DeMay(Executive Officer)Jaye Alison Alfers(Executive Officer)Simon Mark Davidson(Director)John Sheldon Serafini(Executive Officer, Director)inArthur Lewis Money(Director)David Farnsworth(Director)
Co-investorsAlumni VenturesCenter15 CapitalGula Tech AdventuresHemisphere Ventures LLCIceNineManhattan Venture Partners+16 more
Korro Bio is a biotechnology company developing a new class of RNA-editing therapies guided by human genetics and disease biology.
BiotechHealthtechCambridge, US
Nessan Bermingham(Mr. Bermingham is the Executive Chair of the Issuer.)inJean-François Formela(Director)inOmmer Chohan(Mr. Chohan is the Secretary and Treasurer of the Issuer.)inRam Aiyar(Chief Executive Officer, President and Director)inTodd Chappell(Chief Operating Officer)in
Co-investorsAtlas VentureMC Healthcare VenturesNew Enterprise Associates (NEA)AlexandriaQiming Venture PartnersQiming Venture Partners USA+3 more
Monte Rosa develops molecular glue degrader (MGD) therapeutics using MGD chemistry, artificial intelligence, structural biology, and proteomics to target previously undruggable or inadequately drugged disease targets.
AI & Machine LearningBiotechDeep TechHealthtechBoston, US
Markus Warmuth(M.D., Chief Executive Officer)inSharon Townson(Ph.D., Chief Scientific Officer)inJohn Castle(Ph.D., Chief Data and Information Officer)inFilip Janku(M.D., Ph.D., Chief Medical Officer)inPhil Nickson(Ph.D., J.D., Chief Business and Legal Officer)inMagnus Walter(DPhil, Chief Technology Officer)in
Co-investorsAisling CapitalHBM PartnersNew Enterprise Associates (NEA)Versant VenturesAmzak HealthAvoro Capital Advisors+5 more
Navan is an AI-powered platform for corporate travel and expense management that combines booking, policy management, and real-time reporting for enterprise clients.
Enterprise SoftwareFintechSaaSTravel & HospitalityPalo Alto, US
CohenTwigAriel Cohen(Founder)inAurélien Nolf(Chief Financial Officer)inMichael Sindicich(President)inAriel Cohen Ilan Twig(Founder)
Co-investors01 AdvisorsAkkadian VenturesAlkeon InnovationAndreessen HorowitzBase PartnersCoatue Management+20 more
Helicons develops a peptide-based therapeutic platform designed to target intracellular proteins previously considered undruggable by combining the specificity of antibodies with the cell-penetrating properties of small molecules.
AI & Machine LearningBiotechDeep TechMedical Devices
Mathai Mammen(CEO, President and Chairman)in
Co-investorsARCH Venture PartnersCatalio Capital Management, LPForesite CapitalFrazier Life SciencesGeneral CatalystGV (Google Ventures)+10 more
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Schrödinger develops a physics-based computational platform for discovering and optimizing molecules, used to accelerate drug discovery and materials design.
AI & Machine LearningBiotechDeep TechNew MaterialsNew York, US
Richard A. Friesner(Founder)Ramy Farid(Executive Officer, Director)inRamy Farid, Ph.D.(President and CEO, Board Member)Murco Ringnalda(Executive Officer)William Andrew Goddard III(Founder)William Goddard(Founder)
Co-investorsQiming Venture PartnersBill & Melinda Gates Foundation TrustGV (Google Ventures)
Revolutionizing space technology to make life multi-planetary
Hawthorne, US
Elon Musk(Founder)inBret Johnsen(Executive Officer)inGwynne Shotwell(Executive Officer, Director)Tom Mueller(Founder)
BoardAntonio Gracias(Director)inSteve Jurvetson(Director)in
Co-investors1/1 Capital137 Ventures1802 Ventures2080 Ventures3Spoke Capital4DX Ventures+205 more
Bionyra Pharma is a clinical-stage biopharmaceutical company developing next-generation mono and multispecific antibodies for severe immune-mediated inflammatory diseases, with an initial focus on atopic dermatitis and inflammatory bowel disease.
BiotechHealthtech
Frédéric Marrache(Co-founder & CEO)in
Co-investorsJeito CapitalSanofi VenturesSofinnova PartnersVIVES PartnersApollo Health Ventures
Antios Therapeutics develops antiviral therapies for hepatitis B virus (HBV) and other viral diseases, including its Active Site Polymerase Inhibitor Nucleotide (ASPIN) ATI-2173 and a capsid assembly modulator program.
BiotechHealthtechMendham, US
Gregory Mayes(Executive Officer, Director)Douglas Mayers(Executive Officer)inTamra Adams(Executive Officer)inAbel De La Rosa(Director)
BoardIyona Rajkomar(Director)inBenjamin Rovinski(Director)
Co-investorsAisling CapitalAltium CapitalAvego BioScience CapitalLifeSci Venture PartnersPontifax Venture CapitalAmzak Health+8 more
Arcellx develops CAR T-cell therapies that are individually designed for each patient, using the immune system to target and attack cancer.
BiotechHealthtechGaithersburg, US
Han Lee(Executive Officer)Rami Elghandour(Executive Officer, Director)in
BoardJill Carroll(Director)inAli Behbahani(Director)inDerek Yoon(Director)inTiba Aynechi(Director)in
Co-investorsLG Technology VenturesNew Enterprise Associates (NEA)Quan CapitalSamsara BioCapitalSolasta VenturesSR One Capital Management+5 more
Developing microscale robots to deliver therapies locally to targeted brain disease areas.
Co-investorsAlumni VenturesBlue Ivy VenturesBold Capital PartnersCompoundDeep InsightDolby Family Ventures+6 more
Cato Networks provides a cloud-native SASE platform that converges networking, zero-trust security, and access into a single global service for enterprises.
Cloud ComputingCybersecurityEnterprise SoftwareTel Aviv, IL
Shlomo Kramer(Founder)inGur Shatz(Founder)inTomer Wald(Chief Financial Officer)inAlon Alter(Chief Business Officer)inZehorit Mulshanski(Chief People Officer)Eyal Heiman(Chief Technology Officer)in
Co-investorsAcrew CapitalAdams Street PartnersArcher Capital GroupArcher Venture CapitalAspect VenturesBallistic Ventures+13 more
Clearcover is an insurance company that simplifies auto insurance coverage selection and claims processing through a mobile-first platform, enabling fast claim payouts.
InsurTechChicago, US
Kyle Nakatsuji(Founder)inDerek Brigham(Founder)inJennifer Kemp(Executive Officer)Jennifer Crutchfield(Executive Officer)Norman Smagley(Executive Officer)in
BoardCynthia Hardy(Director)
Co-investors500 GlobalAmerican Family VenturesBetter Tomorrow VenturesGeodesic CapitalIA Capital GroupLightbank+7 more
DataGrail provides a software platform that helps companies build and scale comprehensive privacy programs to manage personal data across multiple systems.
AI & Machine LearningCybersecurityData & InfrastructureEnterprise SoftwareSaaS
Daniel Barber(Founder)inIgnacio Zendejas(Founder)inEarl Hathaway(Founder)
Co-investorsBasis Set VenturesFelicis VenturesOperator CollectiveThird Point VenturesThomson Reuters VenturesCloud Apps Capital Partners+7 more
Eclypsium provides hardware and firmware security solutions for enterprises to identify and address vulnerabilities in chips, low-level code, and digital supply chains.
CybersecurityDefense TechEnterprise SoftwareHardwarePortland, US
Yuriy Bulygin(Founder)inAlex Bazhaniuk(Founder)inAlex B(Founder)John Ewert(Executive Officer)in
BoardAlex Doll(Director)inTimothy Porter(Director)in
Co-investorsAlumni VenturesAndreessen HorowitzAV8 VenturesaVentureBasecamp FundDnipro+13 more
Empirical Security builds data-driven models for vulnerability exposure management that predict which CVEs are likely to be exploited in a given organization's environment.
AI & Machine LearningCybersecuritySaaSChicago, US
Edward Bellis(Executive Officer, Director)Michael Roytman(Director)inJason Jacobs(Executive Officer)Stephen Ward(Director)
BoardJohn Cowgill(Director)in
Co-investorsCostanoa VenturesHyde Park AngelsInner Loop CapitalInsight Partners
Everlywell offers at-home lab testing kits and virtual healthcare services across multiple wellness categories including daily health screening, digestive analysis, sexual health testing, and hormone monitoring.
ConsumerDigital HealthHealthtechWellness & Fitness
Julia Cheek(Founder & CEO)in
Co-investorsAnsa CapitalBreyer CapitalCerity Partners VenturesForesite CapitalHalogen Ventures Management Company LlcLux Capital+12 more
Marathon Health provides advanced primary care combined with lifestyle and chronic condition management for employers and health plans, using health coaches and registered dietitians alongside providers.
Digital HealthHealthtechWellness & Fitness
Dr. Jeff Wells(Founder)
Co-investorsAlta PartnersHercules Capital, Inc.New Enterprise Associates (NEA)Endeavor CatalystOak HC/FT
Extracellular is a biomanufacturing company that helps cell-based product developers in cultivated meat, plant cell culture, and bioactives accelerate discovery, overcome production challenges, and commercialize their products.
Advanced ManufacturingBiotechFoodTechNew Materials
Will Milligan(CEO & Founder)in
Co-investorsBig Idea VenturesFFFNewland SyndicateUnruly Capital5AM VenturesAgent Capital+8 more
GlycoEra develops glycan-based therapeutics, applying glycoengineering technology to create biologic drugs.
BiotechHealthtechNewton, US
Ganesh V. Kaundinya(President & CEO)in
Co-investors5AM VenturesCatalio Capital Management, LPLifeArc VenturesRoche Venture FundSofinnova PartnersAgent Capital+1 more
Kinaset Therapeutics is a drug developer working on KN-002, a therapeutic candidate for treating severe asthma across patients regardless of the underlying cause of inflammation.
BiotechHealthtechMedfield, US
Roger Heerman(Chief Business/Operating Officer / Co-Founder)inFrazer Morgan(Chief Development Officer / Co-Founder)inRobert Clarke(Chief Executive Officer / Board Member / Co-Founder)Christopher O’Brien(Chief Medical Officer)
BoardJamil Beg(Director of the Issuer)inTom King(Director of the Issuer)
Co-investors5AM VenturesAtlas VentureRA CapitalEQT Life SciencesGimvVivo Capital+3 more
KnownWell provides virtual and in-person weight-inclusive healthcare for patients with overweight and obesity.
Digital HealthHealthtechWellness & FitnessNeedham, US
Ben Wanamaker(Director)Angela Fitch(Founder)inBrooke Boyarsky Pratt(Founder)in
BoardVineeta Agarwala(Director)inIan Chiang(Director)in
Co-investorsAndreessen HorowitzCVS Health VenturesFlare Capital Partners
Kraken 360 Investments provides capital and launch infrastructure to blockchain protocols in pre-token and early post-token phases, offering custody, staking, treasury, and liquidity services alongside fundraising support.
Crypto & Web3Fintech
Jesse Powell(Founder)inMichael Gronager(Founder)inThanh Luu(Founder)David RipleyinArjun Sethiin
Co-investors1/1 Capital10T Fundalphabet angelsAltari VenturesAweh VenturesBlockchain Capital+49 more
Marathon Health provides an advanced primary care model to employers through onsite, nearsite, network, and virtual health centers, aiming to improve employee health and lower healthcare costs.
Digital HealthHealthtechWellness & Fitness
Jerry Ford(Founder)Rick Ennis(Founder)
Co-investorsGeneral AtlanticNew Enterprise Associates (NEA)Oak HC/FTPotentum PartnersAlta Partners
Nested Therapeutics is a precision oncology company developing small-molecule cancer therapeutics by identifying overlooked driver mutations and novel binding pockets through a drug discovery platform combining genomics, computational biophysics, machine learning, and chemical biology.
AI & Machine LearningBiotechHealthtech
Arvin Dar(Co-founder & Board Observer)inKevan Shokat(Scientific Co-founder)Klaus Hoeflich(Co-founder & former Chief Scientific Officer)inDarrin Miles(Chief Executive Officer)inPhilip Komarnitsky(Chief Medical Officer)inTanja Weber(Chief Business Officer)in
Co-investorsVersant VenturesForesite CapitalCowen Healthcare InvestmentsGoldman SachsSection 32
NextPoint is a precision therapeutics company developing cancer treatments targeting the B7-H7/HHLA2 axis, including a T-cell engager, an antibody-drug conjugate with proprietary linker technology, and a multi-functional checkpoint inhibitor.
BiotechHealthtechAustin, US
Gordon Freeman(Scientific Founder)XingXing Zang(Scientific Founder)inIvan Cheung(Chief Executive Officer)inLeena Gandhi(Chief Medical Officer)inTatiana Novobrantseva(Chief Scientific Officer)inAxel Hoos(Director)
Co-investorsCatalio Capital Management, LPMPM BioImpactSanofi VenturesCatalio Capital ManagementInvusLeaps by Bayer
PandasAI is an open-source library that lets users query data stored in dataframes, databases, or data lakes using natural language to perform analysis and generate visualizations without writing code.
AI & Machine LearningData & InfrastructureEnterprise SoftwareMunich, DE
Gabriele Venturi(Founder)in
Co-investorsEpisode1Runa CapitalY CombinatorVento
Paperspace provided cloud GPU infrastructure and a machine learning development platform, Gradient, for training and deploying AI models.
AI & Machine LearningCloud ComputingDeveloper ToolsDigital HealthEnterprise SoftwareMedical DevicesNew York City, US
Dillon Erb(Founder)inDaniel Kobran(Founder)inOuwen Huang(CEO)
Co-investorsAmino CapitalBoxGroupDCVC (Data Collective)DG Ventures, Inc.FusionInitialized Capital+22 more
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Pelica Health builds an AI operating system for value-based care, helping healthcare organizations close care gaps and manage operations across multiple vendor systems.
AI & Machine LearningEnterprise SoftwareHealthtechSaaSSan Francisco, US
Lalit Kundu(Founder)inCatherine Zhao(Founder)in
Co-investorsY CombinatorDentsu VenturesAndreessen HorowitzLlama venturesMatador FundProgressive Ventures+2 more
Rafay builds infrastructure orchestration and workflow automation software for self-service compute consumption across GPU and CPU environments.
AI & Machine LearningCloud ComputingDeveloper ToolsEnterprise Software
Hanumantha Kavuluru(Founder)Haseeb Budhani(Founder)
Co-investorsFloodgateForgePoint CapitalMoment Ventures, LlcNTT DOCOMO VenturesRidge VenturesCostanoa Ventures+1 more
RedRidge Bio discovers and develops biparatopic antibodies (antibodies that bind two sites on a single protein), including biparatopic antibody-drug conjugates, as therapeutics for oncology and autoimmune diseases.
BiotechHealthtech
Bill Sellers(Scientific Founder and Director Cancer Program, Broad Institute)Stephen Yoder(President & CEO)in
Co-investorsNew Enterprise Associates (NEA)Versant VenturesIDG Capital
Skyvern automates browser-based workflows using AI and computer vision, handling tasks like logging into portals, filling forms, and extracting data without APIs or custom scripts.
AI & Machine LearningData & InfrastructureDeveloper ToolsEnterprise SoftwareSan Francisco, US
Suchintan Singh(Founder)inShuchang Zheng(Founder)inSuchintan Singh Shuchang Zheng(Founder)
Co-investorsY CombinatorCapitalize VCGeneral CatalystKube VCRecursion VenturesSunstone Dream+1 more
Starcloud is a deep-tech company building large-scale data center infrastructure designed to operate in space.
Advanced ManufacturingAI & Machine LearningClimate TechCloud ComputingData & InfrastructureDeep TechSemiconductorsSpace TechRedmond, US
Philip Johnston(Founder)inEzra Feilden(Founder)inAdi Oltean(Founder)inPaul Adrian Oltean(Executive Officer, Director)Philip Johnston Ezra Feilden(Founder)
BoardMorgan Beller(Director)in
Co-investorsAb Capital Holding BVAmbush CapitalCisco InvestmentsDnx VenturesDragon CapitalFUSE+57 more
T-knife Therapeutics is a biopharmaceutical company developing T cell therapies to treat cancer, with an initial focus on solid tumors.
BiotechHealthtechBerlin, DE
Elisa Kieback(Co-founder & Chief Technology Officer)inThomas Blankenstein(Scientific Founder)Thomas Soloway(Chief Executive Officer)Camille Landis(Chief Business Officer / Chief Financial Officer)inPeggy Sotiropoulou(Chief Scientific Officer)in
Co-investorsAndera PartnersVersant VenturesEQT Life SciencesRA CapitalFidelity Investments
Marwan Forzley(Founder)inAldo Carrascoso(Founder)
Co-investorsAB Ventures (Arab Bank)Alumni VenturesBY Venture PartnersDASH VenturesDigital Currency GroupElectric Feel Ventures Llc+7 more
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
AavantgardeAlveusCinCor PharmaCrossbowSeawolfSeawolf Therapeutics
Exits · 8
7 IPOs · 1 acquisitionsHawkEye 360NYSE: HAWKKorro BioNASDAQ: KRROMonte Rosa TherapeuticsNASDAQ: GLUENavanNASDAQ: NAVNParabilis MedicinesNASDAQ: PBLSSchrodingerNASDAQ: SDGRSpaceXNASDAQ: SPCXPaperspaceacq. by DigitalOcean
Portfolio news
latest coverage across their companies
Everly Health · forgeglobal.com · Sep 7, 2026
Starcloud · techcrunch.com · Aug 21, 2026
Cato Networks · Cato Networks · Aug 3, 2026
Empirical Security · fintech.global · Jul 21, 2026
Skyvern · ycombinator.com · Jul 15, 2026
Pelica · ycombinator.com · Jun 25, 2026
Bionyra · finsmes.com · Jun 22, 2026
Eclypsium · securityweek.com · Mar 20, 2026
Frequently asked questions
- How many investments has Sixty Degree Capital made?
- Sixty Degree Capital has 41 tracked investments, 8 of which have exited, including 5 dated in the last 24 months.
- What stage does Sixty Degree Capital invest at?
- Sixty Degree Capital invests at the Pre-Seed, Seed, Series A, Series B, Series C, Growth stages.
- What sectors does Sixty Degree Capital focus on?
- Sixty Degree Capital focuses on AI & Machine Learning, Biotech, Cloud Computing, Cybersecurity, Data & Infrastructure, Developer Tools, Digital Health, Enterprise Software, Fintech, Healthtech, Medical Devices, SaaS.
- Where is Sixty Degree Capital located?
- Sixty Degree Capital is headquartered in North York, CA.
- Does Sixty Degree Capital lead rounds?
- Sixty Degree Capital typically participates in rounds rather than leading them.
- Who does Sixty Degree Capital co-invest with?
- Sixty Degree Capital most often shares deals with New Enterprise Associates (NEA), Alumni Ventures, RA Capital, among 145 tracked co-investors.
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